Detailed information for compound 223832

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 385.813 | Formula: C18H20ClF2N2O3-
  • H donors: 2 H acceptors: 3 LogP: 1.88 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCNCc1c(F)cc2c(c1F)n(cc(c2=O)C(=O)O)C1CC1.[Cl-]
  • InChi: 1S/C18H20F2N2O3.ClH/c1-2-3-6-21-8-12-14(19)7-11-16(15(12)20)22(10-4-5-10)9-13(17(11)23)18(24)25;/h7,9-10,21H,2-6,8H2,1H3,(H,24,25);1H/p-1
  • InChiKey: UBVATLPLQANJPG-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0018 0.0018
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0167 0.036 0.036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0328 0.0729 0.0729
Trypanosoma brucei PAB1-binding protein , putative 0.0016 0.0016 0.0016
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0379 0.0845 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0023 0.0023
Schistosoma mansoni carbonic anhydrase-related 0.206 0.4686 0.4686
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0425 0.0951 0.0951
Brugia malayi EGF-like domain containing protein 0.0033 0.0055 0.0055
Brugia malayi neuropeptide F receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0023 0.0023
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.021
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0048 0.0089 0.0706
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0425 0.0951 0.0951
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0308 0.0683 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) acetylcholine receptor protein 0.0012 0.0005 0.0005
Brugia malayi G-protein coupled receptor 0.0425 0.0951 0.0951
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0001 0.0001
Echinococcus granulosus zinc finger protein 0.0023 0.0033 0.0033
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0052 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0086 0.0175 0.0175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0045 0.0083 0.0083
Loa Loa (eye worm) G protein alpha subunit 3 0.0009 0.0001 0.0001
Schistosoma mansoni microtubule-associated protein tau 0.1712 0.3892 0.3892
Schistosoma mansoni integrin alpha-ps 0.017 0.0368 0.0368
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0048 0.0089 0.0706
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.004 0.007 0.007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0072 0.0573
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0033 0.0251
Onchocerca volvulus 0.0012 0.0005 0.0038
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.4385 1 1
Onchocerca volvulus 0.0063 0.0124 0.0984
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0025 0.0036 0.0036
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0009 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0155 0.0334 0.0334
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.4385 1 1
Leishmania major hypothetical protein, conserved 0.0045 0.0083 0.0083
Brugia malayi AKH receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0023 0.0179
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.017 0.0368 0.0368
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0002
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0033 0.0055 0.029
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0024 0.0033 0.0381
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Brugia malayi nuclear receptor NHR-67 0.0019 0.0023 0.0023
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0009 0.0001 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0425 0.0951 0.0951
Brugia malayi beta-lactamase family protein 0.0045 0.0083 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0095 0.0095
Brugia malayi hypothetical protein 0.0016 0.0016 0.0016
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0023
Echinococcus multilocularis lamin 0.0063 0.0124 0.0124
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0028 0.0028
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0062 0.0121 0.0121
Echinococcus multilocularis multidrug resistance associated protein 7 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Brugia malayi hypothetical protein 0.0505 0.1134 0.1134
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0072 0.0072
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0005 0.0005
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0023 0.0023
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.0437 0.3493
Entamoeba histolytica hypothetical protein 0.004 0.0071 0.0824
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.206 0.4686 0.4686
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0083 0.0083
Onchocerca volvulus 0.0025 0.0036 0.0284
Schistosoma mansoni hypothetical protein 0.004 0.007 0.007
Brugia malayi follicle stimulating hormone receptor 0.0425 0.0951 0.0951
Brugia malayi MH1 domain containing protein 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0025 0.0036 0.0284
Onchocerca volvulus Cathepsin F homolog 0.001 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0014 0.0012 0.0012
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0034 0.0056 0.0056
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0072 0.0072
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.206 0.4686 0.4686
Brugia malayi Cytochrome P450 family protein 0.0048 0.0089 0.0089
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0014 0.0014
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0052 0.0098 0.0098
Mycobacterium tuberculosis Probable hydrolase 0.0045 0.0083 0.1289
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0045 0.0083 0.1289
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0044 0.0079 0.0626
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0072 0.0072
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0425 0.0951 0.0951
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0379 0.0845 0.1804
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0031 0.0031
Brugia malayi Death domain containing protein 0.0016 0.0016 0.0016
Giardia lamblia Multidrug resistance-associated protein 1 0.0034 0.0056 0.0298
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0048 0.0089 0.1386
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni cpg binding protein 0.0032 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0034 0.0056 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0016 0.0016
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0425 0.0951 0.0951
Brugia malayi Cation transporter family protein 0.0025 0.0036 0.0036
Onchocerca volvulus 0.0425 0.0951 0.7601
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0425 0.0951 0.0951
Brugia malayi intermediate filament protein 0.0063 0.0124 0.0124
Echinococcus granulosus neuropeptide FF receptor 2 0.0425 0.0951 0.0951
Brugia malayi Dopamine receptor protein 1 0.0425 0.0951 0.0951
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0023 0.0023
Echinococcus granulosus sex peptide receptor 0.0425 0.0951 0.0951
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0024
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0028 0.0028
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0072 0.0072
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0379 0.0845 0.0845
Onchocerca volvulus 0.001 0.0001 0.0001
Echinococcus granulosus Ankyrin 0.0016 0.0016 0.0016
Schistosoma mansoni neuropeptide receptor 0.0425 0.0951 0.0951
Brugia malayi Dopamine receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis neuropeptide s receptor 0.0958 0.2169 0.2169
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0045 0.0083 0.0083
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Brugia malayi Tachykinin-like peptides receptor 99D 0.0425 0.0951 0.0951
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0031 0.0357
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0024 0.0024
Onchocerca volvulus 0.0425 0.0951 0.7601
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0005 0.0005
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.007 0.0806
Plasmodium falciparum carbonic anhydrase 0.206 0.4686 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Entamoeba histolytica ATP-binding cassette protein, putative 0.0034 0.0056 0.0647
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0072 0.0072
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0023
Loa Loa (eye worm) GABA receptor subunit 0.0013 0.001 0.001
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0385 0.0859 1
Schistosoma mansoni hypothetical protein 0.004 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0489 0.1097 0.1097
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) fibroinase 0.001 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.004 0.0071 0.0824
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0425 0.0951 0.0951
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Echinococcus granulosus orexin receptor type 2 0.0425 0.0951 0.0951
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0009 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0473
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0023
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0009 0.0001 0.0001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.206 0.4686 0.4686
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0048 0.0089 0.1386
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0473
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0023 0.0023
Brugia malayi Cytochrome P450 family protein 0.0069 0.0136 0.0136
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0031 0.0226
Echinococcus granulosus cpg binding protein 0.0032 0.0053 0.0053
Brugia malayi tailless protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.001 0.0001 0.0001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0047 0.0086 0.0086
Trichomonas vaginalis hypothetical protein 0.0033 0.0055 0.0432
Brugia malayi G-protein alpha subunit 0.0009 0.0001 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Brugia malayi Dopamine receptor protein 2 0.0425 0.0951 0.0951
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0167 0.036 0.036
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0028 0.0028
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.004 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.0089 0.0089
Mycobacterium ulcerans esterase/lipase LipP 0.0045 0.0083 0.063
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.022 0.0483 0.0483
Brugia malayi conserved hypotetical protein 0.0019 0.0023 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0072 0.0072
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0001 0.0001
Onchocerca volvulus 0.0012 0.0005 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0048 0.0089 0.1386
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.206 0.4686 0.4686
Schistosoma mansoni hypothetical protein 0.0081 0.0165 0.0165
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0031 0.0031
Echinococcus granulosus nAChR subunit 0.0025 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0024 0.0024
Plasmodium falciparum cysteine proteinase falcipain 2b 0.001 0.0001 0.0002
Brugia malayi Cytochrome P450 family protein 0.0069 0.0136 0.0136
Echinococcus multilocularis g protein coupled receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi hypothetical protein 0.0012 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0425 0.0951 0.0951
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0033 0.0071
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0425 0.0951 0.0951
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0087 0.0177 0.0177
Schistosoma mansoni cathepsin F (C01 family) 0.001 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0425 0.0951 0.0951
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0048 0.0089 0.0706
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0045 0.0045
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.0311 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0024 0.0034 0.0034
Loa Loa (eye worm) intermediate filament protein 0.0063 0.0124 0.0124
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi hypothetical protein 0.0022 0.0028 0.0028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0033 0.0055 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0005 0.0005
Schistosoma mansoni immunophilin 0.0385 0.0859 0.0859
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0034 0.0056 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Conserved protein 0.0101 0.0209 0.3266
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0025 0.0036 0.0036
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Echinococcus multilocularis muscleblind protein 1 0.0308 0.0683 0.0683
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0002
Trichomonas vaginalis fk506-binding protein, putative 0.0052 0.0098 0.0781
Trypanosoma brucei carbonic anhydrase-like protein 0.4385 1 1
Brugia malayi MH2 domain containing protein 0.0017 0.0018 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.022 0.0483 0.0483
Mycobacterium tuberculosis Conserved protein 0.0045 0.0083 0.1289
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0009 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.0023 0.0031 0.0031
Mycobacterium tuberculosis Possible toxin MazF5 0.0101 0.0209 0.3266
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0072 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0425 0.0951 0.0951
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0379 0.0845 0.0845
Schistosoma mansoni neurotransmitter gated ion channel 0.0012 0.0005 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0425 0.0951 0.0951
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0023 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0086 0.0175 0.0175
Loa Loa (eye worm) integrin beta-2 0.0978 0.2214 0.2214
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi larval opioid receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0023 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0425 0.0951 0.0951
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.206 0.4686 0.4686
Giardia lamblia Neurogenic locus notch-like protein 0.0033 0.0055 0.0287
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0048 0.0089 0.0089
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis allatostatin A receptor 0.0425 0.0951 0.0951
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0072 0.0072
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Echinococcus granulosus neuropeptide s receptor 0.0958 0.2169 0.2169
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0005 0.0005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.001 0.001
Brugia malayi G protein-coupled receptor F59B2.13 0.0425 0.0951 0.0951
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0024 0.0034 0.0034
Echinococcus granulosus multidrug resistance associated protein 7 0.0034 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0037 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0308 0.0683 0.0683
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0034 0.0056 0.0056
Echinococcus granulosus beta LACTamase domain containing family member 0.0045 0.0083 0.0083
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0052 0.0098 0.1029
Leishmania major fk506-binding protein 1-like protein 0.0379 0.0845 0.0845
Echinococcus granulosus fibrillin 1 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.004 0.007 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0001 0.0001
Echinococcus granulosus adam 0.0033 0.0055 0.0055
Trypanosoma brucei multidrug resistance protein E 0.0034 0.0056 0.0056
Schistosoma mansoni neuropeptide receptor 0.0425 0.0951 0.0951
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0055 0.0434
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0425 0.0951 0.0951
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0018
Loa Loa (eye worm) Smad1 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0045 0.0083 0.0655
Loa Loa (eye worm) acetyltransferase 0.015 0.0321 0.0321
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0142 0.0142
Mycobacterium tuberculosis Possible toxin MazF1 0.0101 0.0209 0.3266
Giardia lamblia Multidrug resistance-associated protein 1 0.0034 0.0056 0.0306
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0072 0.0072
Loa Loa (eye worm) TYRA-2 protein 0.0425 0.0951 0.0951
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.206 0.4686 0.4686
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0033 0.0055 0.0434
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0015 0.0015
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0033 0.0055 0.0432
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.017 0.0368 0.0368
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0072 0.0072
Schistosoma mansoni acetylcholine receptor subunit beta 0.0012 0.0005 0.0005
Brugia malayi PHD-finger family protein 0.0028 0.0044 0.0044
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Leishmania major carbonic anhydrase-like protein 0.4385 1 1
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0023
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0048 0.0089 0.1386
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Toxin MazF9 0.0101 0.0209 0.3266
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0098 0.0781
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0034 0.0056 0.012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0001 0.0001
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0009 0.0001 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0025 0.0036 0.0036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0031 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.022 0.0483 0.0483
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0425 0.0951 0.0951
Entamoeba histolytica ATP-binding cassette protein, putative 0.0034 0.0056 0.0647
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0052 0.0098 0.0098
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0052 0.0098 0.0098
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0052 0.0098 0.0822
Schistosoma mansoni rab6-interacting 0.002 0.0024 0.0024
Brugia malayi jmjC domain containing protein 0.0036 0.0061 0.0061
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0034 0.0056 0.0056
Schistosoma mansoni lamin 0.0063 0.0124 0.0124
Echinococcus multilocularis integrin alpha ps 0.017 0.0368 0.0368
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0052 0.0098 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0061 0.0061
Onchocerca volvulus 0.001 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0016 0.0016 0.0016
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0012 0.0005 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0031 0.0245
Brugia malayi putative neuropeptide receptor NPR1 0.0425 0.0951 0.0951
Brugia malayi Melatonin receptor type 1A 0.0425 0.0951 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Echinococcus multilocularis serotonin receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0025 0.0036 0.0036
Echinococcus granulosus cytochrome P450 2K1 0.0048 0.0089 0.0089
Brugia malayi nuclear hormone receptor 0.0041 0.0072 0.0072
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0287 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0033 0.0053 0.0053
Echinococcus multilocularis neuropeptide Y receptor 0.0425 0.0951 0.0951
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0071 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0141 0.0141
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0005 0.0005
Brugia malayi hypothetical protein 0.0012 0.0005 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0024 0.0024
Schistosoma mansoni aldehyde dehydrogenase 0.0037 0.0064 0.0064
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0136 0.0136
Entamoeba histolytica ATP-binding cassette protein, putative 0.0034 0.0056 0.0647
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0023 0.0023
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0018 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0038 0.0038
Brugia malayi Intermediate filament tail domain containing protein 0.0063 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0045 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Loa Loa (eye worm) beta-lactamase 0.0045 0.0083 0.0083
Onchocerca volvulus 0.0019 0.0023 0.0179
Echinococcus granulosus RUN 0.002 0.0024 0.0024
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0009 0.0001 0.0001
Echinococcus granulosus expressed protein 0.0377 0.084 0.084
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Mycobacterium ulcerans beta-lactamase 0.0045 0.0083 0.063
Brugia malayi ecdysone receptor 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.029 0.0641 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.001 0.0001 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0005 0.0036
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0012 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0048 0.0089 0.1386
Onchocerca volvulus 0.0063 0.0124 0.0984
Brugia malayi Pre-SET motif family protein 0.0071 0.0141 0.0141
Schistosoma mansoni opsin-like receptor 0.0425 0.0951 0.0951
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0071 0.0071
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0134 0.0286 0.2279
Brugia malayi Doublecortin family protein 0.002 0.0024 0.0024
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0023
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0048 0.0089 0.0706
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0024 0.0024
Giardia lamblia Tenascin-X 0.0033 0.0055 0.0287
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Schistosoma mansoni cathepsin F (C01 family) 0.001 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.001 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.0023 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0048 0.0089 0.1386
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0033 0.0055 0.0055
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0033 0.0025
Echinococcus granulosus lamin 0.0063 0.0124 0.0124
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0033 0.0055 0.0055
Brugia malayi EGF-like domain containing protein 0.0033 0.0055 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Echinococcus multilocularis geminin 0.0358 0.0797 0.0797
Echinococcus granulosus integrin alpha 3 0.0291 0.0643 0.0643
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0058 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Trypanosoma brucei ISWI complex protein 0.0014 0.0012 0.0012
Brugia malayi MH1 domain containing protein 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0013 0.001 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0064 0.0398
Onchocerca volvulus Serine\/threonine kinase homolog 0.0071 0.0142 0.1131
Schistosoma mansoni hypothetical protein 0.0358 0.0797 0.0797
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.4385 1 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0052 0.0098 0.0098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0072 0.0072
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0009 0.0001 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0001 0.0001
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0024 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0425 0.0951 0.0951
Onchocerca volvulus 0.0167 0.036 0.2877
Onchocerca volvulus 0.0041 0.0072 0.0573
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0034 0.0056 0.0056
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0048 0.0089 0.1386
Schistosoma mansoni multidrug resistance protein 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0023 0.0023
Echinococcus multilocularis muscleblind protein 0.0308 0.0683 0.0683
Brugia malayi putative neuropeptide receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0014 0.0014
Giardia lamblia High cysteine protein 0.0033 0.0055 0.0287
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0023 0.0023
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0055 0.0055
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.022 0.0483 0.0483
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0311 0.3434
Brugia malayi cytochrome P450 0.0048 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0018 0.0018
Entamoeba histolytica multidrug resistance protein, putative 0.0034 0.0056 0.0647
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0009 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Schistosoma mansoni hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni immunophilin 0.0385 0.0859 0.0859
Brugia malayi Pre-SET motif family protein 0.0489 0.1097 0.1097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0072 0.0072
Trypanosoma brucei p-glycoprotein 0.0034 0.0056 0.0056
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0012
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0321 0.0321
Echinococcus multilocularis lamin dm0 0.0063 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0156 0.0336 0.0336
Onchocerca volvulus 0.0013 0.001 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0025 0.0036 0.0036
Echinococcus granulosus cathepsin l1 0.001 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.004 0.007 0.007
Loa Loa (eye worm) neuropeptide F receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0025 0.0036 0.0036
Mycobacterium tuberculosis Conserved protein 0.0045 0.0083 0.1289
Brugia malayi hypothetical protein 0.0019 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0072 0.0072
Echinococcus granulosus carbonic anhydrase 0.206 0.4686 0.4686
Echinococcus multilocularis serotonin receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0009 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0086 0.0175 0.0175
Echinococcus granulosus g protein coupled receptor 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0045 0.0083 0.1289
Brugia malayi EGF-like domain containing protein 0.0033 0.0055 0.0055
Leishmania major cysteine peptidase A (CPA) 0.001 0.0001 0.0001
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0025 0.0036 0.0036
Onchocerca volvulus 0.001 0.0001 0.0001
Entamoeba histolytica hypothetical protein, conserved 0.0168 0.0363 0.4222
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0072 0.0072
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0379 0.0845 0.0845
Loa Loa (eye worm) melatonin receptor type 1A 0.0425 0.0951 0.0951
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0425 0.0951 0.0951
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0103 0.0215 0.1711
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0052 0.0098 0.0098
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0168 0.0363 0.0363
Brugia malayi hypothetical protein 0.001 0.0003 0.0003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0031 0.0489
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0023 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0425 0.0951 0.0951
Brugia malayi nuclear receptor NHR-88 0.0019 0.0023 0.0023
Toxoplasma gondii hypothetical protein 0.0033 0.0055 0.0117
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0048 0.0089 0.0706
Echinococcus granulosus GPCR family 2 0.004 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0056
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0034 0.0056 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Entamoeba histolytica hypothetical protein 0.0019 0.0023 0.0263
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0023 0.0023
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0072 0.0573
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.007
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0024 0.0024
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Trypanosoma cruzi ISWI complex protein 0.0014 0.0012 0.0012
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0379 0.0845 0.0845
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0125 0.0265 0.0265
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.0546 0.0546
Onchocerca volvulus 0.0425 0.0951 0.7601
Echinococcus granulosus fibrillin 2 0.0033 0.0055 0.0055
Brugia malayi GnHR receptor homolog 0.0425 0.0951 0.0951
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0072 0.0072
Echinococcus multilocularis nAChR subunit 0.0025 0.0036 0.0036
Echinococcus multilocularis fibrillin 1 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0425 0.0951 0.0951
Schistosoma mansoni hypothetical protein 0.0061 0.0119 0.0119
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0014 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0024 0.0024
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni biogenic amine (5HT) receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0025 0.0036 0.0036
Echinococcus granulosus microtubule associated protein 2 0.1712 0.3892 0.3892
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0055 0.0055
Mycobacterium tuberculosis Toxin MazF2 0.0101 0.0209 0.3266
Brugia malayi nuclear receptor NHR-88 0.0041 0.0072 0.0072
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Echinococcus granulosus biogenic amine 5HT receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis neuropeptide receptor 0.0425 0.0951 0.0951
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0067 0.0133 0.0133
Brugia malayi hypothetical protein 0.0019 0.0023 0.0023
Schistosoma mansoni cpg binding protein 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.206 0.4686 0.4686
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0072 0.0072
Schistosoma mansoni zinc finger protein 0.0023 0.0033 0.0033
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni opsin-like receptor 0.0425 0.0951 0.0951
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0168 0.0363 0.0363
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0023
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.0414 0.3305
Echinococcus multilocularis protein jagged 2 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0074
Toxoplasma gondii cytochrome p450 superfamily protein 0.0048 0.0089 0.0189
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0048 0.0089 0.1386
Echinococcus multilocularis 0.0052 0.0098 0.0098
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0168 0.0363 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.001 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0024 0.0024
Onchocerca volvulus 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0001 0.0001
Echinococcus multilocularis glycine receptor subunit beta 0.0025 0.0036 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0072 0.0072
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0072 0.0072
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0012 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0048 0.0089 0.0706
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0048 0.0089 0.1386
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0385 0.0859 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0052 0.0098 0.0098
Echinococcus granulosus expressed protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0048 0.0089 0.1386
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0168 0.0363 0.0363
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0379 0.0845 0.0845
Brugia malayi hypothetical protein 0.0012 0.0005 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0063 0.0124 0.0124
Trichomonas vaginalis immunophilin, putative 0.0379 0.0845 0.6758
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0425 0.0951 0.0951
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0038 0.0038
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0168 0.0363 0.0363
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0083 0.066
Leishmania major pentamidine resistance protein 1 0.0034 0.0056 0.0056
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0016 0.0016
Echinococcus multilocularis ubiquitin specific protease 41 0.0033 0.0055 0.0055
Brugia malayi PXA domain containing protein 0.0019 0.0023 0.0023
Schistosoma mansoni biogenic amine (5HT) receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0172 0.0172
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0023 0.0179
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0379 0.0845 0.6758
Trichomonas vaginalis esterase, putative 0.0045 0.0083 0.0655
Echinococcus granulosus neuropeptide receptor A26 0.0958 0.2169 0.2169
Onchocerca volvulus 0.0025 0.0036 0.0284
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0071 0.0071
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0048 0.0089 0.0706
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0156 0.0336 0.0336
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0048 0.0089 0.1386
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0385 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0026
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0425 0.0951 0.0951
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0018 0.0018
Mycobacterium tuberculosis Toxin MazF6 0.0101 0.0209 0.3266
Onchocerca volvulus Cathepsin L homolog 0.001 0.0001 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0425 0.0951 0.0951
Toxoplasma gondii cathepsin CPL 0.001 0.0001 0.0002
Schistosoma mansoni adenoreceptor 0.0425 0.0951 0.0951
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0177 0.0177
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0425 0.0951 0.0951
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0072 0.0072
Echinococcus multilocularis neuropeptide receptor 0.0425 0.0951 0.0951
Schistosoma mansoni opsin-like receptor 0.0425 0.0951 0.0951
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0033 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.0437 0.3493
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0024
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Echinococcus granulosus tachykinin peptides receptor 99D 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) integrin alpha pat-2 0.0585 0.1315 0.1315
Echinococcus multilocularis smad 0.0017 0.0018 0.0018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0025 0.0025
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0306 0.0306
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0072 0.0573
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0001 0.0001
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0168 0.0168
Onchocerca volvulus 0.001 0.0001 0.0001
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0379 0.0845 0.0845
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0048 0.0089 0.0706
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0024 0.0024
Giardia lamblia Neurogenic locus Notch protein precursor 0.0033 0.0055 0.0287
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0016 0.0016
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0018 0.0018
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0033 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0025 0.0036 0.0036
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0012 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.022 0.0483 0.0483
Schistosoma mansoni acetylcholine receptor-related 0.0012 0.0005 0.0005
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0024 0.0034 0.0034
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0136 0.0136
Schistosoma mansoni neuropeptide F-like receptor 0.0425 0.0951 0.0951
Echinococcus granulosus neuropeptides capa receptor 0.0425 0.0951 0.0951
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi Kelch motif family protein 0.0156 0.0336 0.0336
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0072 0.0072
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0045 0.0083 0.063
Schistosoma mansoni amine GPCR 0.0425 0.0951 0.0951
Echinococcus multilocularis fmrfamide receptor 0.0425 0.0951 0.0951
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0379 0.0845 0.0845
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0038 0.0038
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0298 0.0659 0.0659
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0072 0.0072
Echinococcus granulosus allatostatin A receptor 0.0425 0.0951 0.0951
Schistosoma mansoni survival motor neuron protein 0.0103 0.0215 0.0215
Onchocerca volvulus Huntingtin homolog 0.011 0.023 0.1838
Schistosoma mansoni histamine h1 receptor 0.0425 0.0951 0.0951
Brugia malayi RE15519p 0.0425 0.0951 0.0951
Echinococcus granulosus cathepsin l cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Echinococcus granulosus glycine receptor subunit beta 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.023
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0025 0.0036 0.0036
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0052 0.0098 0.0241
Onchocerca volvulus 0.0045 0.0083 0.0655
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0009 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0071 0.0141 0.03
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor 0.0425 0.0951 0.0951
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0062 0.0062
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0032 0.0053 0.0053
Echinococcus granulosus histone lysine methyltransferase setb 0.0087 0.0177 0.0177
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0118 0.0118
Brugia malayi G-protein coupled receptor 0.0425 0.0951 0.0951
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.007 0.0149
Schistosoma mansoni hypothetical protein 0.0016 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0045 0.0083 0.1289
Echinococcus granulosus peptide allatostatin:somatostatin 0.0425 0.0951 0.0951
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Schistosoma mansoni neuropeptide receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0413 0.0922 0.0922
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0177 0.0177
Echinococcus multilocularis survival motor neuron protein 1 0.0505 0.1134 0.1134
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0072 0.0072
Schistosoma mansoni neurotransmitter gated ion channel 0.0013 0.001 0.001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0083 0.066
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0052 0.0098 0.0822
Brugia malayi ABC transporter transmembrane region family protein 0.0034 0.0056 0.0056
Giardia lamblia Hypothetical protein 0.0052 0.0098 0.0822
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0083 0.0083
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0016 0.0016
Toxoplasma gondii hypothetical protein 0.0027 0.0042 0.0089
Brugia malayi steroid hormone receptor 0.0041 0.0072 0.0072
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0136 0.0136
Schistosoma mansoni aldehyde dehydrogenase 0.0037 0.0064 0.0064
Leishmania major peptidylprolyl isomerase-like protein 0.0379 0.0845 0.0845
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0136 0.0136
Onchocerca volvulus 0.002 0.0024 0.0191
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.4385 1 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0033 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0033 0.0055 0.0434
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0085 0.0172 0.0172
Onchocerca volvulus 0.0425 0.0951 0.7601
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Echinococcus multilocularis glycine receptor subunit beta 0.0025 0.0036 0.0036
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0072 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0125 0.0265 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0033 0.0521
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Schistosoma mansoni Smad4 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0125 0.0265 0.0265
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0072 0.0072
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.023
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0168 0.0363 0.0363
Echinococcus multilocularis carbonic anhydrase II 0.4385 1 1
Echinococcus multilocularis RUN 0.002 0.0024 0.0024
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0013 0.001 0.001
Schistosoma mansoni fk506 binding protein 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.004 0.007 0.007
Brugia malayi ORL1-like opioid receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0031 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.4385 1 1
Echinococcus multilocularis carbonic anhydrase 0.206 0.4686 0.4686
Onchocerca volvulus 0.0425 0.0951 0.7601
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0024 0.0034 0.0034
Brugia malayi excitatory GABA receptor EXP-1A 0.0025 0.0036 0.0036
Leishmania major cathepsin L-like protease 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Onchocerca volvulus 0.0557 0.1251 1
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0014 0.0014
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0052 0.0098 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.038 0.0848 0.0848
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni immunophilin 0.0333 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0072 0.0072
Schistosoma mansoni netrin receptor unc5 0.0016 0.0016 0.0016
Brugia malayi hypothetical protein 0.011 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0071 0.0142 0.0142
Brugia malayi EGF-like domain containing protein 0.0033 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0168 0.0363 0.0363
Onchocerca volvulus Neuropeptide F receptor homolog 0.0425 0.0951 0.7601
Echinococcus granulosus glycine receptor subunit beta 0.0025 0.0036 0.0036
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0018 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0072 0.0072
Brugia malayi hypothetical protein 0.002 0.0024 0.0024
Loa Loa (eye worm) doublecortin family protein 0.002 0.0024 0.0024
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0106 0.0106
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0001 0.0001
Echinococcus granulosus FK506 binding protein 2 0.0052 0.0098 0.0098
Schistosoma mansoni multidrug resistance protein 0.0034 0.0056 0.0056
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Schistosoma mansoni smad 0.0017 0.0018 0.0018
Schistosoma mansoni neuropeptide f receptor 76f 0.0425 0.0951 0.0951
Loa Loa (eye worm) cytochrome P450 family protein 0.0153 0.033 0.033
Echinococcus granulosus carbonic anhydrase 0.206 0.4686 0.4686
Trypanosoma cruzi ISWI complex protein 0.0014 0.0012 0.0012
Echinococcus granulosus somatostatin receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0015 0.0015
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0172 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi Muscleblind-like protein 0.0308 0.0683 0.0683
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0025 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Onchocerca volvulus 0.0425 0.0951 0.7601
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0379 0.0845 0.0845
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0052 0.0098 0.021
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0168 0.0363 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.0363 0.29
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.0089 0.1996
Schistosoma mansoni nAChR subunit 0.0012 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0061 0.0061
Mycobacterium tuberculosis Possible toxin MazF7 0.0101 0.0209 0.3266
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0033 0.0055 0.0055
Trypanosoma cruzi hypothetical protein 0.0026 0.0038 0.0038
Echinococcus multilocularis GPCR, family 2 0.004 0.007 0.007
Onchocerca volvulus Putative nachr subunit 0.0025 0.0036 0.0284
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0005 0.0005
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0024 0.029
Echinococcus multilocularis fibrillin 2 0.0033 0.0055 0.0055
Schistosoma mansoni rab6-interacting 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Schistosoma mansoni polycystin 1-related 0.0129 0.0273 0.0273
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0016 0.0122
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0018
Echinococcus granulosus tm gpcr rhodopsin 0.0425 0.0951 0.0951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Echinococcus multilocularis Ankyrin 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0379 0.0845 1
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0033 0.0033
Mycobacterium ulcerans hypothetical protein 0.009 0.0184 0.1873
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0072 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.004 0.007 0.007
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.1162
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0072 0.0072
Onchocerca volvulus 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0168 0.0363 0.0363
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0005 0.0005
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0083 0.0983
Loa Loa (eye worm) hypothetical protein 0.206 0.4686 0.4686
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Echinococcus multilocularis dro:myosuppressin receptor 0.0425 0.0951 0.0951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0072 0.0072
Mycobacterium ulcerans hypothetical protein 0.0045 0.0083 0.063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0005 0.0005
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0009 0.0009
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0168 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Trichomonas vaginalis fk506 binding protein, putative 0.0052 0.0098 0.0781
Onchocerca volvulus 0.0052 0.0098 0.0781
Echinococcus granulosus g protein coupled receptor 0.0425 0.0951 0.0951
Brugia malayi cytoplasmic intermediate filament protein 0.0034 0.0056 0.0056
Echinococcus multilocularis sex peptide receptor 0.0425 0.0951 0.0951
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Echinococcus multilocularis orexin receptor type 2 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0052 0.0098 0.0098
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0071 0.0141 0.0141
Brugia malayi Bromodomain containing protein 0.0075 0.015 0.015
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0172 0.0172
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0048 0.0089 0.1386
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0041 0.0072 0.0072
Trichomonas vaginalis penicillin-binding protein, putative 0.0045 0.0083 0.0655
Onchocerca volvulus 0.0012 0.0005 0.0038
Brugia malayi Cation transporter family protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0052 0.0098 0.0098
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0425 0.0951 0.0951
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0425 0.0951 0.0951
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0036 0.0036
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0045 0.0083 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis Smad4 0.0017 0.0018 0.0018
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0052 0.0098 0.1534
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0047 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0049 0.0049
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0071 0.0142 0.0142
Brugia malayi Smad1 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0038 0.0038
Brugia malayi CXXC zinc finger family protein 0.0029 0.0045 0.0045
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0023 0.0023
Echinococcus multilocularis cpg binding protein 0.0032 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Brugia malayi hypothetical protein 0.0019 0.0023 0.0023
Brugia malayi Cation transporter family protein 0.0167 0.036 0.036
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0048 0.0089 0.0706
Onchocerca volvulus 0.0425 0.0951 0.7601
Echinococcus multilocularis fmrfamide receptor 0.0425 0.0951 0.0951
Schistosoma mansoni multidrug resistance protein 0.0034 0.0056 0.0056
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0425 0.0951 0.0951
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.0658 0.766
Echinococcus multilocularis zinc finger protein 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0001 0.0001
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0007 0.0007
Mycobacterium ulcerans lipase LipD 0.0045 0.0083 0.063
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0016 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0028 0.0028
Schistosoma mansoni carbonic anhydrase 0.206 0.4686 0.4686
Brugia malayi Latrophilin receptor protein 2 0.004 0.007 0.007
Trypanosoma cruzi cruzipain precursor, putative 0.0036 0.0062 0.0062
Brugia malayi sulfakinin receptor protein 0.0425 0.0951 0.0951
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) cysteine protease 0.001 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0072 0.0072
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0425 0.0951 0.0951
Echinococcus granulosus geminin 0.0358 0.0797 0.0797
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0005 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0425 0.0951 0.0951
Loa Loa (eye worm) FKBP5 protein 0.0379 0.0845 0.0845
Echinococcus granulosus dro:myosuppressin receptor 0.0425 0.0951 0.0951
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0071 0.0142 0.0142
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0009 0.0001 0.0001
Giardia lamblia Kinase, PLK 0.0071 0.0142 0.136
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0048 0.0089 0.0706
Treponema pallidum fructose-bisphosphate aldolase 0.0297 0.0658 0.7754
Trypanosoma brucei polo-like protein kinase 0.0071 0.0142 0.0142
Echinococcus granulosus fmrfamide receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0036 0.0036
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0025 0.0036 0.0036
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Echinococcus multilocularis musashi 0.0063 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Brugia malayi Cytochrome P450 family protein 0.0153 0.033 0.033
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0012 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0016 0.0016
Schistosoma mansoni amine GPCR 0.0425 0.0951 0.0951
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0081 0.0163 0.0163
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0005 0.0005
Leishmania major p-glycoprotein e 0.0034 0.0056 0.0056
Trichomonas vaginalis penicillin-binding protein, putative 0.0045 0.0083 0.0655
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0072 0.0072
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0037 0.0064 0.0064
Echinococcus multilocularis 0.0048 0.0089 0.0089
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0044 0.0079 0.0626
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0033 0.0395
Brugia malayi Uncoordinated protein 44 0.0016 0.0016 0.0016
Brugia malayi serine/threonine-protein kinase plk-2 0.0071 0.0142 0.0142
Onchocerca volvulus Huntingtin homolog 0.011 0.023 0.1838
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Echinococcus multilocularis neuropeptide Y receptor 0.0425 0.0951 0.0951
Brugia malayi Putative carbonic anhydrase 5 precursor 0.4385 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0031 0.0371
Onchocerca volvulus 0.0167 0.036 0.2877
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Echinococcus granulosus nAChR subunit 0.0013 0.001 0.001
Onchocerca volvulus 0.001 0.0001 0.0001
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0385 0.0859 0.0859
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0048 0.0089 0.1386
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Onchocerca volvulus 0.0029 0.0045 0.0357
Echinococcus granulosus carbonic anhydrase II 0.4385 1 1
Mycobacterium leprae Probable lipase LipE 0.0045 0.0083 0.1773
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0033 0.0055 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0045 0.0083 0.0655
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0025 0.0036 0.0036
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0016
Giardia lamblia Multidrug resistance-associated protein 1 0.0034 0.0056 0.0306
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Loa Loa (eye worm) G-protein coupled receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Echinococcus multilocularis integrin alpha 3 0.0291 0.0643 0.0643
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0023 0.0023
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0031 0.0049 0.0049
Echinococcus granulosus g-protein coupled receptor 0.0425 0.0951 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0015 0.0015
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0072 0.0072
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0023 0.0023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0425 0.0951 0.0951
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0062 0.0062
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0072 0.0072
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0031 0.0031
Echinococcus multilocularis g-protein coupled receptor 0.0425 0.0951 0.0951
Giardia lamblia hypothetical protein 0.0033 0.0055 0.0287
Echinococcus granulosus carbonic anhydrase 0.206 0.4686 0.4686
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.007 0.0473
Brugia malayi multidrug resistance related protein 1 0.0034 0.0056 0.0056
Schistosoma mansoni integrin beta subunit 0.0605 0.1361 0.1361
Schistosoma mansoni bromodomain containing protein 0.0064 0.0126 0.0126
Entamoeba histolytica hypothetical protein 0.0019 0.0023 0.0263
Echinococcus granulosus lamin dm0 0.0063 0.0124 0.0124
Echinococcus multilocularis adam 0.0033 0.0055 0.0055
Echinococcus granulosus alpha 1A adrenergic receptor 0.0425 0.0951 0.0951
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0012 0.0005 0.0005
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.0642 0.5129
Onchocerca volvulus 0.002 0.0024 0.0191
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.1238 0.2807 1
Schistosoma mansoni amine GPCR 0.0425 0.0951 0.0951
Leishmania major cathepsin L-like protease 0.001 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0048 0.0089 0.0706
Loa Loa (eye worm) hypothetical protein 0.0063 0.0124 0.0124
Schistosoma mansoni biogenic amine receptor 0.0425 0.0951 0.0951
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0025 0.0036 0.0036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0072 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0425 0.0951 0.0951
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) G-protein coupled receptor 0.0425 0.0951 0.0951
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0037 0.0064 0.0064
Echinococcus multilocularis cysteine protease 0.001 0.0001 0.0001
Onchocerca volvulus 0.0053 0.0101 0.0803
Loa Loa (eye worm) ACC-1 protein 0.0025 0.0036 0.0036
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0321 0.0321
Brugia malayi G protein-coupled receptor 0.0425 0.0951 0.0951
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Loa Loa (eye worm) carbonic anhydrase 3 0.4385 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Brugia malayi Bromodomain containing protein 0.0039 0.0069 0.0069
Brugia malayi Serotonin receptor 0.0425 0.0951 0.0951
Echinococcus granulosus neuropeptide receptor 0.0425 0.0951 0.0951
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0048 0.0089 0.1386
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0022 0.0028 0.0028
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0072 0.0072
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0031 0.0031
Schistosoma mansoni zinc finger protein 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0019 0.0023 0.0023
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0425 0.0951 0.0951
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0071 0.0142 0.0142
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0425 0.0951 0.0951
Brugia malayi Calcitonin receptor-like protein seb-1 0.0125 0.0265 0.0265
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.0658 0.766
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0379 0.0845 0.6758
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Onchocerca volvulus 0.0425 0.0951 0.7601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0023 0.0023
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0124 0.0264
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0025 0.0036 0.0036
Echinococcus multilocularis cysteine protease 0.001 0.0001 0.0001
Echinococcus multilocularis integrin beta 2 0.0761 0.1718 0.1718
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0083 0.0977
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0005 0.0005
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.206 0.4686 0.4686
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0425 0.0951 0.0951
Toxoplasma gondii hypothetical protein 0.206 0.4686 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0425 0.0951 0.0951
Toxoplasma gondii exonuclease III APE 0.0023 0.0031 0.0067
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0005 0.0005
Echinococcus granulosus g protein coupled receptor 0.0425 0.0951 0.0951
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0333 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0048 0.0089 0.0706
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0001 0.0001
Echinococcus multilocularis integrin alpha ps 0.017 0.0368 0.0368
Schistosoma mansoni cytochrome P450 0.0048 0.0089 0.0089
Mycobacterium leprae putative cytochrome p450 0.0048 0.0089 0.1996
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0012 0.0005 0.0005
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Trichomonas vaginalis set domain proteins, putative 0.0556 0.1251 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0297 0.0658 0.7702
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.0016 0.0016
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0168 0.0363 0.0363
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0425 0.0951 0.0951
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Brugia malayi nuclear receptor RXR 0.0019 0.0023 0.0023
Schistosoma mansoni multidrug resistance protein 0.0034 0.0056 0.0056
Plasmodium vivax SET domain protein, putative 0.0071 0.0141 0.1662
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0023 0.0023
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0072 0.0072
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Schistosoma mansoni hypothetical protein 0.002 0.0024 0.0024
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0086 0.0086
Giardia lamblia Tenascin-like 0.0033 0.0055 0.0287
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.029 0.0642 0.0642
Echinococcus multilocularis neuropeptide receptor A26 0.0958 0.2169 0.2169
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0379 0.0845 0.0845
Echinococcus multilocularis carbonic anhydrase 0.206 0.4686 0.4686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni integrin alpha-ps 0.0089 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0089 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0425 0.0951 0.0951
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0036 0.0036
Schistosoma mansoni myosin xvIII 0.0425 0.0951 0.0951
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.001 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0072 0.0072
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0031 0.0031
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0045 0.0083 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Trichomonas vaginalis fk506-binding protein, putative 0.0379 0.0845 0.6758
Loa Loa (eye worm) papain family cysteine protease containing protein 0.001 0.0001 0.0001
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0333 0.074 0.074
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0072 0.0072
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0025 0.0036 0.0036
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0061 0.0061
Schistosoma mansoni lipoxygenase 0.0056 0.0106 0.0106
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0005 0.0005
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.029 0.0642 0.0642
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0034 0.0056 0.0056
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.0016 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0072 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.0425 0.0951 0.0951
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0055 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0125 0.0125
Leishmania major cathepsin L-like protease 0.0036 0.0062 0.0062
Loa Loa (eye worm) cytochrome P450 0.0048 0.0089 0.0089
Onchocerca volvulus Cathepsin L homolog 0.001 0.0001 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0072 0.0072
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Brugia malayi Integrin beta pat-3 precursor 0.0978 0.2214 0.2214
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0136 0.1283
Onchocerca volvulus 0.0425 0.0951 0.7601
Mycobacterium tuberculosis Probable lipase LipE 0.0045 0.0083 0.1289
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0052 0.0098 0.021
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0379 0.0845 0.0845
Echinococcus multilocularis somatostatin receptor 0.0425 0.0951 0.0951
Echinococcus granulosus dnaJ subfamily B 0.0413 0.0922 0.0922
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0052 0.0098 0.1137
Plasmodium vivax vivapain-2 0.001 0.0001 0.001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0033 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0425 0.0951 0.0951
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0014 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.004 0.007 0.007
Entamoeba histolytica hypothetical protein 0.004 0.0071 0.0824
Schistosoma mansoni hypothetical protein 0.0052 0.0098 0.0098
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0028 0.0028
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0009 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0019 0.0023 0.0263
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0033 0.0071
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0038 0.0038
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0033 0.0007
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0425 0.0951 0.0951
Leishmania major ABC-thiol transporter 0.0034 0.0056 0.0056
Giardia lamblia Tenascin-37 0.0033 0.0055 0.0287
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Schistosoma mansoni GTP-binding protein alpha subunit 0.0009 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.206 0.4686 0.4686
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0024 0.0024
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0321 0.0321
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0045 0.0083 0.0655
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Giardia lamblia ABC transporter, putative 0.0034 0.0056 0.0306
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0072 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Loa Loa (eye worm) ctsf protein 0.001 0.0001 0.0001
Schistosoma mansoni lipoxygenase 0.002 0.0024 0.0024
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0083 0.0177
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0025 0.0036 0.0036
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0072 0.0072
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0005 0.0005
Entamoeba histolytica DNA repair and recombination protein, putative 0.0168 0.0363 0.4222
Schistosoma mansoni loxhd1 0.002 0.0024 0.0024
Echinococcus multilocularis integrin alpha ps 0.0081 0.0165 0.0165
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Schistosoma mansoni amine GPCR 0.0425 0.0951 0.0951
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0379 0.0845 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Echinococcus multilocularis multidrug resistance associated protein 4 0.0026 0.0038 0.0038
Brugia malayi beta-lactamase 0.0045 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0167 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0052 0.0098 0.0241
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0001 0.0001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.0089 0.0089
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0045 0.0083 0.1289
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0031 0.0031
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0055 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0064 0.0398
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0005 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0016 0.0016 0.0184
Onchocerca volvulus 0.0019 0.0023 0.0179
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0311 0.4853
Echinococcus granulosus integrin beta 2 0.0761 0.1718 0.1718
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Echinococcus granulosus ubiquitin specific protease 41 0.0033 0.0055 0.0055
Brugia malayi jmjC domain containing protein 0.0033 0.0053 0.0053
Echinococcus granulosus 7TM GPCR rhodopsin 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0037 0.0064 0.0994
Plasmodium vivax vivapain-2 0.001 0.0001 0.001
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.0038 0.0038
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0033 0.0025
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0005 0.0005
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0013 0.001 0.001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0425 0.0951 0.0951
Brugia malayi ecdysteroid receptor 0.0041 0.0072 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0033 0.0055 0.0632
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0048 0.0089 0.1386
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.004 0.007 0.007
Leishmania major hypothetical protein, conserved 0.0016 0.0016 0.0016
Brugia malayi neuropeptide F receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0134 0.0286 0.0286
Entamoeba histolytica ATP-binding cassette protein, putative 0.0034 0.0056 0.0647
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0023 0.0023
Echinococcus granulosus serotonin receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.022 0.0483 0.0483
Echinococcus multilocularis fk506 binding protein 0.0379 0.0845 0.0845
Brugia malayi hypothetical protein 0.0156 0.0336 0.0336
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0425 0.0951 0.0951
Echinococcus granulosus integrin alpha ps 0.017 0.0368 0.0368
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0033 0.0055 0.0055
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0001 0.0001
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0005 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0118 0.0118
Onchocerca volvulus 0.0425 0.0951 0.7601
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0025 0.0036 0.0036
Echinococcus granulosus Smad4 0.0017 0.0018 0.0018
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0025 0.0036 0.0036
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0009 0.0001 0.0001
Echinococcus granulosus smad 0.0017 0.0018 0.0018
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0081 0.0163 0.0163
Onchocerca volvulus 0.0045 0.0083 0.0655
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0023
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Echinococcus granulosus intermediate filament protein 0.0063 0.0124 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Echinococcus granulosus survival motor neuron protein 1 0.0505 0.1134 0.1134
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0024 0.0052
Brugia malayi MH2 domain containing protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0209 0.0457 0.0457
Echinococcus granulosus death domain containing protein 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0083 0.0083
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0009 0.0001 0.0001
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi hypothetical protein 0.004 0.0071 0.0071
Onchocerca volvulus 0.0425 0.0951 0.7601
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Possible toxin MazF4 0.0101 0.0209 0.3266
Onchocerca volvulus 0.0425 0.0951 0.7601
Schistosoma mansoni amine GPCR 0.0425 0.0951 0.0951
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1519 0.3451 0.3451
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0048 0.0089 0.1386
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0048 0.0089 0.0706
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0031 0.0067
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Echinococcus multilocularis nAChR subunit 0.0013 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.022 0.0483 0.0483
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0505 0.1134 0.1134
Echinococcus multilocularis g protein coupled receptor 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0048 0.0089 0.1386
Brugia malayi hypothetical protein 0.002 0.0024 0.0024
Onchocerca volvulus 0.0167 0.036 0.2877
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0425 0.0951 0.0951
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0052 0.0098 0.0822
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0048 0.0089 0.1386
Entamoeba histolytica ABC transporter, putative 0.0034 0.0056 0.0647
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0072 0.0072
Entamoeba histolytica hypothetical protein 0.004 0.0071 0.0824
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0061 0.0061
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0009 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0083
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0379 0.0845 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Plasmodium falciparum cysteine proteinase falcipain 2a 0.001 0.0001 0.0002
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0034 0.0056 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0083 0.0083
Schistosoma mansoni growth hormone secretagogue receptor 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0095 0.0095
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.022 0.0483 0.0483
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0024 0.0024
Echinococcus granulosus muscleblind protein 0.0308 0.0683 0.0683
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.0546 0.0546
Brugia malayi MH2 domain containing protein 0.0248 0.0546 0.0546
Echinococcus multilocularis expressed protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) ACC-1 protein 0.0025 0.0036 0.0036
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0055 0.0055
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0005 0.0005
Echinococcus multilocularis multidrug resistance associated protein 1 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0028 0.0028
Loa Loa (eye worm) LGC-31 protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0425 0.0951 0.0951
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0106 0.0106
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0379 0.0845 1
Trypanosoma brucei hypothetical protein, conserved 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Echinococcus multilocularis carbonic anhydrase 0.206 0.4686 0.4686
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0034 0.0056 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable lipase LipD 0.0045 0.0083 0.1289
Toxoplasma gondii ABC1 family protein 0.0045 0.0083 0.0176
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0425 0.0951 0.0951
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0023 0.0181
Schistosoma mansoni hypothetical protein 0.0103 0.0215 0.0215
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0025 0.0036 0.0036
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0425 0.0951 0.7601
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.0038 0.0038
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0033 0.0055 0.0055
Leishmania major cytochrome p450-like protein 0.0048 0.0089 0.0089
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0005 0.0005
Leishmania major cytochrome p450-like protein 0.0069 0.0136 0.0136
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0072 0.0072
Echinococcus multilocularis G protein coupled receptor 139 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0048 0.0089 0.1386
Leishmania major cathepsin L-like protease 0.0036 0.0062 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0425 0.0951 0.0951
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.004 0.007 0.007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0081 0.0165 0.0165
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0052 0.0098 0.021
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0005 0.0005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Echinococcus multilocularis expressed protein 0.0377 0.084 0.084
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0025 0.0036 0.0036
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0048 0.0089 0.0089
Brugia malayi beta-lactamase family protein 0.0045 0.0083 0.0083
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0009 0.0001 0.0001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0052 0.0098 0.2338
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0036 0.0036
Echinococcus granulosus integrin alpha ps 0.0081 0.0165 0.0165
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.001
Leishmania major cathepsin L-like protease 0.0036 0.0062 0.0062
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0052 0.0098 0.0098
Schistosoma mansoni intermediate filament proteins 0.0063 0.0124 0.0124
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni nuclear receptor 0.0019 0.0023 0.0023
Echinococcus granulosus multidrug resistance associated protein 1 0.0034 0.0056 0.0056
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0033 0.0071
Schistosoma mansoni neuropeptide receptor 0.0425 0.0951 0.0951
Onchocerca volvulus 0.0071 0.0141 0.1119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.022 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Giardia lamblia MRP-like ABC transporter 0.0034 0.0056 0.0306
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0658 0.5262
Schistosoma mansoni carbonic anhydrase-related 0.206 0.4686 0.4686
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0009 0.0001 0.0001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0007 0.0007
Brugia malayi hypothetical protein 0.0009 0.0001 0.0001
Trypanosoma brucei mitochondrial DNA polymerase beta 0.017 0.0368 0.0368
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0023 0.0023
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0015 0.0015
Echinococcus granulosus G protein coupled receptor 139 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) DR-78 0.0019 0.0023 0.0023
Echinococcus granulosus hypothetical protein 0.0425 0.0951 0.0951
Toxoplasma gondii aldehyde dehydrogenase 0.0037 0.0064 0.0136
Giardia lamblia Tenascin precursor 0.0033 0.0055 0.0287
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0287 0.0635 0.0635
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0048 0.0089 0.1386
Leishmania major cytochrome p450-like protein 0.0048 0.0089 0.0089
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0025 0.0036 0.0036
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0048 0.0089 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0072 0.0072
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0036 0.0036
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0025 0.0036 0.0036
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0048 0.0089 0.0706
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0052 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0167 0.036 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni carbonic anhydrase-related 0.206 0.4686 0.4686
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0013 0.0013
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0036 0.0036
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0005 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0045 0.0083 0.0655
Schistosoma mansoni nAChR subunit 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0034 0.0056 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Trypanosoma cruzi multidrug resistance protein E, putative 0.0034 0.0056 0.0056
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0036 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.009 0.0184 0.2869
Mycobacterium ulcerans hypothetical protein 0.0101 0.0209 0.2186
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0414 0.3306
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0072 0.0072
Toxoplasma gondii LsmAD domain-containing protein 0.0016 0.0016 0.0033
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0009 0.0001 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0136 0.0136
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0048 0.0089 0.0706
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0048 0.0089 0.0706
Entamoeba histolytica serine/threonine protein kinase, putative 0.0071 0.0142 0.1647
Schistosoma mansoni nuclear receptor 0.0019 0.0023 0.0023
Giardia lamblia Rrm3p helicase 0.0168 0.0363 0.4076
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0086 0.0086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0425 0.0951 0.0951
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0033 0.0053 0.0053
Echinococcus granulosus cathepsin L cysteine proteinase 0.001 0.0001 0.0001
Mycobacterium leprae conserved hypothetical protein 0.0045 0.0083 0.1773
Echinococcus granulosus multidrug resistance associated protein 4 0.0026 0.0038 0.0038
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0023
Trichomonas vaginalis fk506-binding protein, putative 0.0052 0.0098 0.0781
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0425 0.0951 0.0951
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0048 0.0089 0.0706
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0425 0.0951 0.0951
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0098 0.1137
Echinococcus granulosus rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Echinococcus multilocularis rhodopsin orphan GPCR 0.0425 0.0951 0.0951
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0142 0.1131
Leishmania major mitochondrial DNA polymerase beta 0.017 0.0368 0.0368
Brugia malayi Serotonin receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Giardia lamblia High cysteine protein 0.0033 0.0055 0.0287
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0048 0.0089 0.0706
Brugia malayi hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0358 0.0797 0.0797
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0048 0.0089 0.0706
Loa Loa (eye worm) multidrug resistance-associated protein 0.0026 0.0039 0.0039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0064 0.0398
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0048 0.0089 0.0706
Brugia malayi PXA domain containing protein 0.0019 0.0023 0.0023
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0052 0.0098 0.0822
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0425 0.0951 0.0951
Brugia malayi nuclear hormone receptor 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0025 0.0036 0.0036
Brugia malayi N-terminal motif family protein 0.0134 0.0286 0.0286
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0023 0.0023
Schistosoma mansoni integrin alpha 0.0379 0.0846 0.0846
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0023 0.0023
Brugia malayi nuclear receptor RXR 0.0022 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0013 0.001 0.0106
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0083 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0031 0.0245
Loa Loa (eye worm) hypothetical protein 0.0425 0.0951 0.0951
Schistosoma mansoni kinase 0.0036 0.0062 0.0062
Brugia malayi Integrin alpha pat-2 precursor 0.0379 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0072
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0031 0.0031
Mycobacterium tuberculosis Probable esterase LipL 0.0045 0.0083 0.1289
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0181
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0081 0.0163 0.0163
Echinococcus granulosus 7tm_1 domain containing protein 0.0425 0.0951 0.0951
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0087 0.0177 0.0177
Leishmania major cathepsin L-like protease 0.001 0.0001 0.0001
Schistosoma mansoni neurotransmitter gated ion channel 0.0012 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0098 0.0781
Echinococcus multilocularis beta LACTamase domain containing family member 0.0045 0.0083 0.0083
Echinococcus multilocularis neuropeptides capa receptor 0.0425 0.0951 0.0951
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0025 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0019 0.0023 0.0023
Echinococcus multilocularis microtubule associated protein 2 0.1712 0.3892 0.3892
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0053 0.0053
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0425 0.0951 0.0951
Brugia malayi hypothetical protein 0.0425 0.0951 0.0951
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0036 0.0062 0.0062
Brugia malayi Cathepsin L-like precursor 0.001 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0005 0.0005
Schistosoma mansoni zinc finger protein 0.0014 0.0012 0.0012
Onchocerca volvulus 0.0033 0.0055 0.0432
Schistosoma mansoni lamin 0.0063 0.0124 0.0124
Mycobacterium tuberculosis Toxin MazF3 0.0101 0.0209 0.3266
Onchocerca volvulus 0.0085 0.0172 0.1373
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0425 0.0951 0.0951

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) <= 0.049 ug ml-1 In vitro antibacterial activity against gram-negative K. pneumoniae ChEMBL. 14698166
MIC (functional) = 0.098 ug ml-1 In vitro antibacterial activity against gram-negative Citrobacter freundii ChEMBL. 14698166
MIC (functional) = 0.39 ug ml-1 In vitro antibacterial activity against gram-negative S. boydii ChEMBL. 14698166
MIC (functional) = 3.13 ug ml-1 In vitro antibacterial activity against gram-positive S. pneumoniae ChEMBL. 14698166
MIC (functional) > 6.25 ug ml-1 In vitro antibacterial activity against gram-positive S. aureus ChEMBL. 14698166
MIC (functional) > 6.25 ug ml-1 In vitro antibacterial activity against gram-positive S. epidermidis ChEMBL. 14698166

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.