Detailed information for compound 30590

Basic information

Technical information
  • TDR Targets ID: 30590
  • Name: phenethylcarbamoylphosphonic acid
  • MW: 229.17 | Formula: C9H12NO4P
  • H donors: 3 H acceptors: 4 LogP: -0.03 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(P(=O)(O)O)NCCc1ccccc1
  • InChi: 1S/C9H12NO4P/c11-9(15(12,13)14)10-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,11)(H2,12,13,14)
  • InChiKey: GHFCXEYUGIXTHN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [oxo-(phenethylamino)methyl]phosphonic acid
  • 2-phenylethylcarbamoylphosphonic acid
  • [oxo-(2-phenylethylamino)methyl]phosphonic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References
Homo sapiens carbonic anhydrase XII Starlite/ChEMBL References
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Trypanosoma cruzi carbonic anhydrase-like protein, putative carbonic anhydrase XII 354 aa 295 aa 23.1 %
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, putative 0.1696 0.3519 0.4357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Loa Loa (eye worm) hypothetical protein 0.0134 0.0234 0.029
Giardia lamblia Hypothetical protein 0.0069 0.0096 0.0303
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0062 0.0083 0.0102
Plasmodium vivax vivapain-2 0.1363 0.2817 1
Echinococcus multilocularis cathepsin b 0.3859 0.8067 0.8067
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0015 0.0015
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0026 0.0007 0.0009
Leishmania major kinesin, putative 0.0802 0.1638 0.4646
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.011 0.011
Trypanosoma cruzi cysteine proteinase, putative 0.0755 0.1538 0.19
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0076 0.011 0.0137
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.0042 0.0052
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Leishmania major DNA polymerase eta, putative 0.0048 0.0052 0.0129
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0139 0.0243 0.08
Schistosoma mansoni peroxidasin 0.0107 0.0177 0.0219
Schistosoma mansoni thyroid hormone receptor 0.0165 0.0299 0.037
Plasmodium vivax serine-repeat antigen (SERA), putative 0.034 0.0667 0.2348
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0076 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Onchocerca volvulus 0.02 0.0372 0.0997
Brugia malayi proteasome subunit beta type 1 0.012 0.0204 0.0253
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.011 0.0137
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1363 0.2817 1
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0019 0.0033
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0114 0.0191 0.019
Loa Loa (eye worm) carbonic anhydrase 3 0.0248 0.0473 0.0586
Plasmodium falciparum carbonic anhydrase 0.0134 0.0234 0.0807
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.1363 0.2817 0.3491
Brugia malayi cathepsin L precursor 0.034 0.0667 0.0827
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3286 0.6861 0.8504
Loa Loa (eye worm) acetyltransferase 0.0142 0.025 0.031
Brugia malayi Protein kinase domain containing protein 0.0066 0.009 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Treponema pallidum NADH oxidase 0.0035 0.0026 0.5
Onchocerca volvulus Matrilysin homolog 0.0051 0.0059 0.0159
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0022 0.0041
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0026 0.0007 0.0009
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0755 0.1538 0.4361
Echinococcus multilocularis calcyphosin protein 0.0034 0.0024 0.0023
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0015 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0032 0.004
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0019 0.0043
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.028 0.0539 0.1516
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.028 0.0339
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0015 0.0015
Schistosoma mansoni biogenic amine receptor 0.0076 0.011 0.0137
Leishmania major protein kinase, putative 0.02 0.0372 0.1039
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Giardia lamblia Calmodulin 0.0034 0.0024 0.0056
Plasmodium falciparum plasmepsin VII 0.0051 0.0059 0.0185
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1289 0.2662 0.3294
Brugia malayi KE2 family protein 0.0065 0.0088 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.149 0.3086 0.8766
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0156 0.028 0.0778
Entamoeba histolytica grainin 2 0.0234 0.0444 0.1555
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.0469 0.9447
Echinococcus granulosus Transglutaminase 0.0069 0.0096 0.0096
Schistosoma mansoni amine GPCR 0.0076 0.011 0.0137
Entamoeba histolytica cysteine proteinase, putative 0.1363 0.2817 1
Brugia malayi calpain D 0.0487 0.0975 0.1208
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0086 0.0085
Onchocerca volvulus 0.0031 0.0016 0.0043
Onchocerca volvulus 0.0031 0.0016 0.0043
Loa Loa (eye worm) animal heme peroxidase 0.0107 0.0177 0.0219
Brugia malayi Animal haem peroxidase family protein 0.0107 0.0177 0.0219
Trichomonas vaginalis centrin, putative 0.0034 0.0024 0.0056
Brugia malayi Blistered cuticle protein 3 0.0107 0.0177 0.0219
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0233 0.0442 0.8882
Brugia malayi fibroinase precursor 0.034 0.0667 0.0827
Mycobacterium tuberculosis Probable oxidoreductase 0.0259 0.0496 1
Loa Loa (eye worm) hypothetical protein 0.3859 0.8067 1
Echinococcus granulosus tar DNA binding protein 0.0064 0.0086 0.0085
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Loa Loa (eye worm) hypothetical protein 0.0162 0.0293 0.0363
Onchocerca volvulus Cathepsin L homolog 0.1363 0.2817 0.7551
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0243 0.08
Trypanosoma brucei metacaspase MCA2 0.0043 0.0042 0.0099
Trypanosoma cruzi cysteine protease, putative 0.0755 0.1538 0.19
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Schistosoma mansoni cpg binding protein 0.0087 0.0133 0.0165
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3286 0.6861 0.8504
Onchocerca volvulus 0.0031 0.0016 0.0043
Plasmodium falciparum cysteine proteinase falcipain 3 0.1363 0.2817 1
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0231 0.0438 0.0437
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0026 0.0054
Toxoplasma gondii aspartyl protease ASP1 0.0162 0.0293 0.0774
Echinococcus multilocularis neuropeptide receptor 0.0076 0.011 0.011
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0019 0.0018
Schistosoma mansoni hypothetical protein 0.02 0.0372 0.0461
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0006 0.0008
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Leishmania major cytochrome p450-like protein 0.0049 0.0054 0.0133
Schistosoma mansoni hypothetical protein 0.008 0.0121 0.0149
Echinococcus granulosus cathepsin L cysteine proteinase 0.1363 0.2817 0.2816
Trypanosoma cruzi kinesin, putative 0.0802 0.1638 0.2024
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.011 0.011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1568 0.325 0.4023
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0204 0.0381 0.0472
Trichomonas vaginalis calpain, putative 0.0487 0.0975 0.3282
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.034 0.0667 0.2238
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0692
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0166 0.0166
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0076 0.011 0.0137
Brugia malayi hypothetical protein 0.0051 0.0059 0.0073
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0014 0.0017
Leishmania major cathepsin L-like protease 0.1363 0.2817 0.8
Loa Loa (eye worm) hypothetical protein 0.0067 0.0093 0.0115
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0032 0.004
Leishmania major hypothetical protein, conserved 0.0357 0.0703 0.1982
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0051 0.0059 0.0073
Echinococcus multilocularis caspase 8 0.0043 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Schistosoma mansoni hypothetical protein 0.0682 0.1386 0.1719
Toxoplasma gondii calcium-dependent protein kinase 0.0204 0.0381 0.1012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.034 0.0667 0.2238
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0032 0.052
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.02 0.0372 0.1237
Brugia malayi Cell death protein 3 precursor 0.0083 0.0126 0.0156
Echinococcus multilocularis transmembrane protease serine 3 0.008 0.0121 0.012
Plasmodium falciparum cysteine repeat modular protein 1 0.0066 0.009 0.0295
Leishmania major cathepsin L-like protease 0.1363 0.2817 0.8
Echinococcus multilocularis allatostatin A receptor 0.0076 0.011 0.011
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0044 0.0044 0.0055
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.02 0.0372 0.0371
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.011 0.0137
Echinococcus multilocularis neuropeptide s receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0024 0.0029
Trypanosoma brucei conserved protein 0.023 0.0435 0.1219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Toxoplasma gondii calcium binding egf domain-containing protein 0.0044 0.0044 0.0101
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0044
Echinococcus granulosus proteasome prosome macropain 0.0156 0.028 0.0279
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0015 0.0019
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Trypanosoma brucei calmodulin, putative 0.02 0.0372 0.1039
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0117 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.034 0.0667 0.2238
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0215 0.0258
Trypanosoma cruzi prefoldin subunit, putative 0.0065 0.0088 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.0703 0.0863
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0356 0.0441
Echinococcus multilocularis hypothetical protein 0.1289 0.2662 0.2661
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.0149
Onchocerca volvulus 0.0076 0.011 0.0296
Brugia malayi proteasome subunit alpha type 4 0.0026 0.0007 0.0009
Leishmania major silent information regulator 2, putative 0.0125 0.0215 0.0592
Trichomonas vaginalis chromobox protein, putative 0.0042 0.004 0.0113
Onchocerca volvulus Peroxidasin homolog 0.0107 0.0177 0.0474
Trichomonas vaginalis calcium binding protein, putative 0.02 0.0372 0.1237
Echinococcus granulosus calcium uptake protein 1 0.0204 0.0381 0.038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1568 0.325 0.9233
Trypanosoma brucei carbonic anhydrase-like protein 0.0248 0.0473 0.1326
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.034 0.0667 0.2238
Giardia lamblia Cathepsin B precursor 0.1429 0.2956 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Brugia malayi sulfakinin receptor protein 0.0076 0.011 0.0137
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0015 0.0041
Mycobacterium leprae PROBABLE HYDROLASE 0.0028 0.0011 0.0074
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.011 0.011
Echinococcus granulosus programmed cell death protein 0.0234 0.0444 0.0443
Onchocerca volvulus Peroxidasin homolog 0.0107 0.0177 0.0474
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0476 0.059
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0052 0.0065
Loa Loa (eye worm) matrixin family protein 0.0051 0.0059 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.034 0.0667 0.0827
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma brucei I/6 autoantigen 0.02 0.0372 0.1039
Echinococcus multilocularis dna polymerase eta 0.0048 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis proteasome subunit beta type 7 0.0026 0.0007 0.0006
Trypanosoma cruzi I/6 autoantigen, putative 0.02 0.0372 0.0453
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0011
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.02 0.0372 0.1039
Loa Loa (eye worm) hypothetical protein 0.0134 0.0234 0.029
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0076 0.0095
Loa Loa (eye worm) glutathione reductase 0.0102 0.0166 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.0667 0.2238
Echinococcus granulosus serotonin receptor 0.0076 0.011 0.011
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0215 0.074
Brugia malayi EF hand family protein 0.0204 0.0381 0.0472
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0019 0.0018
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0079 0.0118 0.0117
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0707 0.1438 0.1776
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0156 0.028 0.0347
Loa Loa (eye worm) ctsf protein 0.1363 0.2817 0.3491
Echinococcus granulosus neuropeptide receptor 0.0076 0.011 0.011
Trypanosoma brucei calpain-like protein, putative 0.1289 0.2662 0.7559
Echinococcus granulosus Tolloid protein 1 0.0137 0.024 0.0239
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0039 0.0109
Schistosoma mansoni chromobox protein 0.007 0.0099 0.0122
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0707 0.1438 0.1776
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0076 0.011 0.0137
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0071 0.0088
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.034 0.0667 0.0827
Onchocerca volvulus 0.0076 0.011 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0948 0.1945 0.6573
Onchocerca volvulus 0.1363 0.2817 0.7551
Echinococcus granulosus 7tm_1 domain containing protein 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0019 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.011 0.011
Echinococcus multilocularis programmed cell death protein 0.0234 0.0444 0.0443
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0231 0.0438 0.0437
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0166 0.3256
Trichomonas vaginalis centrin, putative 0.0034 0.0024 0.0056
Loa Loa (eye worm) proteasome subunit beta type 2 0.0049 0.0055 0.0068
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.034 0.0667 0.2348
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0032 0.0032
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0017 0.0021
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.011 0.0137
Schistosoma mansoni hypothetical protein 0.0066 0.009 0.0112
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0054 0.0058
Brugia malayi Pre-SET motif family protein 0.0094 0.0149 0.0185
Loa Loa (eye worm) hypothetical protein 0.0051 0.0059 0.0073
Onchocerca volvulus Matrix metalloproteinase homolog 0.0051 0.0059 0.0159
Echinococcus granulosus peptide allatostatin:somatostatin 0.0076 0.011 0.011
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0019 0.0445
Onchocerca volvulus 0.008 0.0121 0.0323
Schistosoma mansoni egf-like domain protein 0.004 0.0035 0.0043
Leishmania major small myristoylated protein-2 0.0693 0.141 0.3994
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0026 0.0007 0.0009
Schistosoma mansoni neuronal calcium sensor 0.02 0.0372 0.0461
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0156 0.028 0.558
Brugia malayi cathepsin L-like precursor 0.0948 0.1945 0.2411
Echinococcus multilocularis tumor protein p63 0.0328 0.0641 0.064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0019 0.0043
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0221 0.0415 0.1163
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0032
Plasmodium vivax aspartyl protease, putative 0.0051 0.0059 0.0185
Giardia lamblia Cathepsin B precursor 0.034 0.0667 0.2238
Loa Loa (eye worm) hypothetical protein 0.0304 0.059 0.0732
Giardia lamblia Cysteine protease 0.034 0.0667 0.2238
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0156 0.028 0.0972
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.011 0.011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0017 0.0021
Trypanosoma brucei small myristoylated protein 1-2 0.0381 0.0752 0.212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0015 0.0019
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.008 0.0121 0.012
Echinococcus granulosus caspase 2 0.0083 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis proteasome (prosome, macropain) 0.0156 0.028 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0215 0.0214
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0016 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.2599 0.5417 0.6715
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0079 0.0118 0.03
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0042 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.009 0.0103
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1568 0.325 0.9233
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0026 0.0007 0.0009
Entamoeba histolytica grainin, putative 0.0204 0.0381 0.1331
Onchocerca volvulus 0.0076 0.011 0.0296
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0079 0.0118 0.03
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Plasmodium falciparum serine repeat antigen 5 0.034 0.0667 0.2348
Giardia lamblia Cysteine protease 0.034 0.0667 0.2238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Onchocerca volvulus 0.0076 0.011 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0755 0.1538 0.5194
Trypanosoma brucei hypothetical protein, conserved 0.0357 0.0703 0.1982
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1289 0.2662 0.3294
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.0042 0.0052
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.011 0.0137
Brugia malayi larval opioid receptor 0.0076 0.011 0.0137
Onchocerca volvulus 0.0031 0.0016 0.0043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1289 0.2662 0.3294
Brugia malayi hypothetical protein 0.0034 0.0022 0.0028
Schistosoma mansoni cpg binding protein 0.0091 0.0144 0.0178
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma cruzi centrin, putative 0.0234 0.0444 0.0542
Trichomonas vaginalis hypothetical protein 0.0487 0.0975 0.3282
Mycobacterium ulcerans lipase LipD 0.0039 0.0032 0.0933
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0156 0.028 0.0926
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0019 0.0024
Trypanosoma cruzi metacaspase, putative 0.0043 0.0042 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.011 0.011
Brugia malayi Animal haem peroxidase family protein 0.0107 0.0177 0.0219
Toxoplasma gondii cathepsin CPC2 0.034 0.0667 0.1785
Schistosoma mansoni biogenic amine receptor 0.0076 0.011 0.0137
Trichomonas vaginalis chromobox protein, putative 0.007 0.0099 0.0311
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.034 0.0667 0.2348
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0156 0.028 0.558
Onchocerca volvulus 0.0031 0.0016 0.0043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3859 0.8067 1
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.02 0.0372 0.0461
Trypanosoma cruzi 20S proteasome subunit 0.0049 0.0055 0.006
Brugia malayi Dopamine receptor 0.0076 0.011 0.0137
Brugia malayi programmed cell death protein 6 0.02 0.0372 0.0461
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0032 0.0032
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0271 0.027
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus lamin 0.0057 0.0071 0.007
Onchocerca volvulus 0.0031 0.0016 0.0043
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0026 0.0007 0.0009
Echinococcus multilocularis fmrfamide receptor 0.0076 0.011 0.011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Schistosoma mansoni carbonic anhydrase-related 0.0134 0.0234 0.029
Brugia malayi RE15519p 0.0076 0.011 0.0137
Plasmodium falciparum calpain 0.0487 0.0975 0.3444
Trichomonas vaginalis calcium binding proteins, putative 0.02 0.0372 0.1237
Schistosoma mansoni ef hand domain family member A2 0.02 0.0372 0.0461
Brugia malayi proteasome subunit beta type 3 0.0026 0.0007 0.0009
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0221 0.0415 0.1163
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0582 0.1175 0.1449
Plasmodium vivax proteasome subunit beta type-1, putative 0.012 0.0204 0.0702
Brugia malayi proteasome subunit beta type 2 0.0049 0.0055 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0054
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0707 0.1438 0.1776
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0015 0.0019
Leishmania major trypanothione reductase 0.0102 0.0166 0.0454
Loa Loa (eye worm) hypothetical protein 0.0106 0.0175 0.0217
Trichomonas vaginalis peptide N-glycanase, putative 0.0069 0.0096 0.0303
Brugia malayi Tachykinin-like peptides receptor 99D 0.0076 0.011 0.0137
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.02 0.0372 0.0453
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0052 0.0056
Plasmodium vivax aspartyl protease, putative 0.0051 0.0059 0.0185
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0044 0.0044 0.0055
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Schistosoma mansoni intermediate filament proteins 0.0057 0.0071 0.0088
Trypanosoma brucei Calpain-like protein 2 0.0842 0.1721 0.4881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0034 0.0092
Echinococcus multilocularis Myosin regulatory light chain 0.0034 0.0024 0.0023
Brugia malayi Probable myosin regulatory light chain 0.0039 0.0033 0.0041
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0166 0.0166
Plasmodium vivax serine-repeat antigen (SERA) 0.034 0.0667 0.2348
Brugia malayi G protein-coupled receptor F59B2.13 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0026 0.0007 0.0009
Schistosoma mansoni calmodulin related calcium binding protein 0.02 0.0372 0.0461
Trypanosoma brucei trypanothione reductase 0.0102 0.0166 0.0454
Schistosoma mansoni nuclear hormone receptor 0.003 0.0015 0.0019
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0015 0.0019
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.0026 0.5
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0015 0.0019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) fibroinase 0.1363 0.2817 0.3491
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0861 0.1761 0.2176
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0054
Schistosoma mansoni hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0025
Loa Loa (eye worm) trypsin family protein 0.008 0.0121 0.0149
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0215 0.0214
Loa Loa (eye worm) myosin regulatory light chain 1 0.0034 0.0024 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Onchocerca volvulus Peroxidase homolog 0.0107 0.0177 0.0474
Echinococcus multilocularis EF HAND 1, calcium binding site 0.02 0.0372 0.0371
Plasmodium vivax serine-repeat antigen (SERA) 0.034 0.0667 0.2348
Onchocerca volvulus 0.008 0.0121 0.0323
Loa Loa (eye worm) hypothetical protein 0.02 0.0372 0.0461
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0066 0.009 0.0295
Entamoeba histolytica cysteine proteinase, putative 0.0948 0.1945 0.6898
Trypanosoma brucei hypothetical protein 0.0766 0.1563 0.443
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Schistosoma mansoni opsin-like receptor 0.0076 0.011 0.0137
Brugia malayi G-protein coupled receptor 0.0076 0.011 0.0137
Trypanosoma brucei Metacaspase-4 0.0043 0.0042 0.0099
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0259 0.0496 1
Brugia malayi cathepsin L-like cysteine proteinase 0.034 0.0667 0.0827
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0414 0.0823 0.102
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0076 0.011 0.0137
Plasmodium falciparum serine repeat antigen 2 0.034 0.0667 0.2348
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Giardia lamblia Cathepsin B precursor 0.034 0.0667 0.2238
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Onchocerca volvulus 0.0051 0.0059 0.0158
Trichomonas vaginalis chromobox protein, putative 0.007 0.0099 0.0311
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.02 0.0372 0.0461
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1568 0.325 0.4023
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0159 0.0197
Schistosoma mansoni calmodulin-related 0.0034 0.0024 0.0029
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0645 0.1308 0.1621
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0049 0.0055 0.0054
Mycobacterium ulcerans hypothetical protein 0.0039 0.0032 0.0933
Echinococcus granulosus 7TM GPCR rhodopsin 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0061 0.0068
Trichomonas vaginalis esterase, putative 0.0039 0.0032 0.0086
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0076 0.011 0.0137
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.02 0.0372 0.1237
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0826 0.1689 0.2087
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0015 0.0015
Toxoplasma gondii calmodulin CAM2 0.0034 0.0024 0.0045
Onchocerca volvulus 0.0076 0.011 0.0296
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Leishmania major hypothetical protein, conserved 0.0066 0.009 0.0236
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3859 0.8067 1
Loa Loa (eye worm) hypothetical protein 0.0231 0.0438 0.0543
Leishmania major hypothetical protein, conserved 0.0204 0.0381 0.1065
Echinococcus granulosus sex peptide receptor 0.0076 0.011 0.011
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0019 0.0024
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Onchocerca volvulus 0.02 0.0372 0.0997
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Entamoeba histolytica proteasome subunit beta type 1, putative 0.012 0.0204 0.0702
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1022 0.2101 0.5964
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0016 0.0019
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0049 0.0055 0.0054
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0707 0.1438 0.4076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Echinococcus granulosus neurocalcin 0.02 0.0372 0.0371
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.0667 0.2238
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0032 0.004
Brugia malayi calpain family protein 1 0.3086 0.644 0.7983
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.149 0.3086 0.3819
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0959 0.1969 0.5587
Brugia malayi Papain family cysteine protease containing protein 0.1363 0.2817 0.3491
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Plasmodium vivax aspartyl proteinase, putative 0.0051 0.0059 0.0185
Entamoeba histolytica calpain family cysteine protease, putative 0.0487 0.0975 0.3444
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0022 0.0019
Schistosoma mansoni calmodulin 0.02 0.0372 0.0461
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0076 0.0188
Giardia lamblia Proteasome subunit beta type 1 0.012 0.0204 0.0669
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Trypanosoma cruzi caltractin, putative 0.02 0.0372 0.0453
Leishmania major sir2-family protein-like protein 0.0032 0.0019 0.0035
Onchocerca volvulus 0.0096 0.0153 0.0409
Brugia malayi proteasome subunit alpha type 2 0.0026 0.0007 0.0009
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0134 0.0234 0.029
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0166 0.0198
Echinococcus multilocularis calpain 5 0.1289 0.2662 0.2661
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0021
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0076 0.011 0.0137
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Giardia lamblia Dipeptidyl-peptidase I precursor 0.034 0.0667 0.2238
Echinococcus multilocularis sex peptide receptor 0.0076 0.011 0.011
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.025 0.0249
Schistosoma mansoni hypothetical protein 0.0487 0.0975 0.1208
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0042 0.0094
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.624
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus proteasome subunit beta type 7 0.0026 0.0007 0.0006
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.025 0.031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.012 0.0204 0.0669
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1398 0.3962
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Plasmodium vivax SET domain protein, putative 0.0094 0.0149 0.0507
Brugia malayi calpain family protein 1 0.3086 0.644 0.7983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0019 0.0035
Onchocerca volvulus 0.0087 0.0133 0.0358
Echinococcus granulosus g-protein coupled receptor 0.0076 0.011 0.011
Toxoplasma gondii microneme protein, putative 0.0031 0.0016 0.0025
Schistosoma mansoni caspase-7 (C14 family) 0.0114 0.0191 0.0236
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0707 0.1438 0.1776
Onchocerca volvulus Notchless protein homolog 0.0026 0.0007 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma brucei kinesin, putative 0.0802 0.1638 0.4646
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0076 0.011 0.011
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0025
Toxoplasma gondii aspartyl protease 0.0051 0.0059 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.02 0.0372 0.1237
Echinococcus multilocularis neuronal calcium sensor 0.02 0.0372 0.0371
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0019 0.0035
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0049 0.0055 0.006
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0039 0.0087
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0076 0.011 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0015 0.0019
Echinococcus multilocularis laminin 0.0044 0.0044 0.0044
Onchocerca volvulus 0.0304 0.059 0.1582
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0015 0.0041
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0021
Trypanosoma brucei Calpain-like protein CALP1.3 0.0707 0.1438 0.4076
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0076 0.011 0.0137
Trypanosoma brucei calmodulin, putative 0.0204 0.0381 0.1065
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0015 0.0019
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0133 0.0165
Loa Loa (eye worm) hypothetical protein 0.0414 0.0823 0.102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Trypanosoma cruzi metacaspase, putative 0.0043 0.0042 0.0043
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0139 0.0243 0.0242
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Schistosoma mansoni alpha-1 adrenergic receptor 0.0076 0.011 0.0137
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.02 0.0372 0.1298
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1363 0.2817 0.9529
Schistosoma mansoni peptidylglycine monooxygenase 0.0123 0.021 0.026
Brugia malayi Pre-SET motif family protein 0.0645 0.1308 0.1621
Leishmania major calmodulin-like protein 0.02 0.0372 0.1039
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0076 0.011 0.011
Loa Loa (eye worm) TYRA-2 protein 0.0076 0.011 0.0137
Brugia malayi Papain family cysteine protease containing protein 0.034 0.0667 0.0827
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1429 0.2956 0.8396
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Onchocerca volvulus 0.1363 0.2817 0.7551
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0134 0.0234 0.029
Entamoeba histolytica grainin 2 0.0034 0.0024 0.0059
Echinococcus multilocularis cysteine protease 0.1363 0.2817 0.2816
Trichomonas vaginalis caltractin, putative 0.0034 0.0024 0.0056
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3859 0.8067 1
Brugia malayi Papain family cysteine protease containing protein 0.0755 0.1538 0.1907
Echinococcus multilocularis muscleblind protein 0.0152 0.0271 0.027
Mycobacterium tuberculosis Probable dehydrogenase 0.0233 0.0442 0.8882
Echinococcus multilocularis calbindin 32 0.0204 0.0381 0.038
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0159 0.0197
Plasmodium falciparum proteasome subunit beta type-5 0.0156 0.028 0.0972
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0026 0.0064
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0487 0.0976 0.2758
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0049 0.0055 0.0163
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Brugia malayi hypothetical protein 0.0469 0.0938 0.1163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.001
Schistosoma mansoni hypothetical protein 0.0096 0.0153 0.0189
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0015 0.0019
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.011 0.0137
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0026 0.0051
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.02 0.0372 0.0453
Echinococcus granulosus survival motor neuron protein 1 0.0469 0.0938 0.0937
Echinococcus multilocularis calpain 0.1289 0.2662 0.2661
Brugia malayi Cathepsin L-like cysteine proteinase 0.0948 0.1945 0.2411
Toxoplasma gondii histone lysine methyltransferase SET1 0.0171 0.0311 0.0822
Echinococcus multilocularis proteasome subunit alpha type 2 0.0026 0.0007 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.2719
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0755 0.1538 0.1907
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.034 0.0667 0.2348
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0117 0.0116
Leishmania major centrin, putative 0.02 0.0372 0.1039
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.008 0.0121 0.012
Giardia lamblia Proteasome subunit beta type 2 0.0049 0.0055 0.0163
Brugia malayi Matrixin family protein 0.0056 0.0069 0.0085
Giardia lamblia Sirtuin type 2 0.0032 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0132 0.0228 0.0283
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.0356 0.0441
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.034 0.0667 0.0827
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1665 0.3453 0.3453
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Brugia malayi cahepsin L-like non-peptiedase homolog 0.034 0.0667 0.0827
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0039 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.02 0.0372 0.1237
Brugia malayi Trypsin family protein 0.008 0.0121 0.0149
Loa Loa (eye worm) animal heme peroxidase 0.0107 0.0177 0.0219
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Mycobacterium ulcerans putative transglutaminase-like protein 0.0069 0.0096 0.3274
Toxoplasma gondii proteasome subunit beta type, putative 0.0156 0.028 0.0739
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1289 0.2662 0.7559
Loa Loa (eye worm) calpain D 0.0487 0.0975 0.1208
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Leishmania major calmodulin-like protein 0.02 0.0372 0.1039
Schistosoma mansoni calmodulin 0.02 0.0372 0.0461
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.034 0.0667 0.2348
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0017 0.0016
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3859 0.8067 1
Schistosoma mansoni hypothetical protein 0.008 0.0121 0.0149
Entamoeba histolytica protein kinase, putative 0.0802 0.1638 0.5807
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0248 0.0473 0.0586
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0026 0.0007 0.0006
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0076 0.011 0.011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Brugia malayi GnHR receptor homolog 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0215 0.0214
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0028 0.0011 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Trypanosoma cruzi calmodulin, putative 0.02 0.0372 0.0453
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0026 0.0067
Plasmodium vivax plasmepsin IV, putative 0.0162 0.0293 0.1018
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0088 0.0275
Brugia malayi Cathepsin L-like precursor 0.0948 0.1945 0.2411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Echinococcus multilocularis carbonic anhydrase 0.0134 0.0234 0.0233
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0026 1
Entamoeba histolytica calcium-binding protein, putative 0.02 0.0372 0.1298
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0766 0.1563 0.443
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0017 0.0033
Toxoplasma gondii ABC1 family protein 0.0039 0.0032 0.0069
Onchocerca volvulus 0.0076 0.011 0.0296
Schistosoma mansoni reticulocalbin 0.0204 0.0381 0.0472
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0076 0.011 0.011
Trypanosoma cruzi conserved protein 0.0717 0.1458 0.1801
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.009 0.0112
Echinococcus multilocularis musashi 0.0057 0.0071 0.007
Plasmodium vivax glutathione reductase, putative 0.0102 0.0166 0.0567
Onchocerca volvulus 0.0076 0.011 0.0296
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Echinococcus granulosus neuropeptide receptor 0.0076 0.011 0.011
Trypanosoma brucei mitochondrial calcium uptake 1 0.02 0.0372 0.1039
Plasmodium falciparum centrin-4 0.0034 0.0024 0.0059
Loa Loa (eye worm) hypothetical protein 0.0099 0.0159 0.0197
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0248 0.0473 0.0586
Schistosoma mansoni neuropeptide receptor 0.0076 0.011 0.0137
Giardia lamblia Cysteine protease 0.034 0.0667 0.2238
Plasmodium falciparum serine repeat antigen 9 0.034 0.0667 0.2348
Schistosoma mansoni hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Onchocerca volvulus 0.008 0.0121 0.0323
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Echinococcus granulosus cathepsin L cysteine protease 0.0755 0.1538 0.1538
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0026 0.0386
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.02 0.0372 0.1298
Giardia lamblia Cathepsin B precursor 0.034 0.0667 0.2238
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.011 0.011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0026 0.0692
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1282 0.2647 0.3276
Echinococcus granulosus FTZ F1 alpha 0.003 0.0015 0.0015
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0076 0.011 0.0137
Leishmania major phospholipase c-like protein 0.02 0.0372 0.1039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0015 0.0019
Echinococcus granulosus geminin 0.0682 0.1386 0.1386
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0017 0.0016
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3859 0.8067 1
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0248 0.0473 0.0586
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0015 0.0019
Schistosoma mansoni amine GPCR 0.0076 0.011 0.0137
Echinococcus granulosus peroxidasin 0.0107 0.0177 0.0176
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0414 0.0823 0.102
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0071 0.0088
Echinococcus granulosus proteasome subunit alpha type 6 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0035 0.0043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0629 0.0772
Echinococcus granulosus centrin 2 0.02 0.0372 0.0371
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Trypanosoma brucei calpain-like protein, putative 0.1289 0.2662 0.7559
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0032 0.0091
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0052
Leishmania major hypothetical protein, conserved 0.0039 0.0032 0.0073
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0215 0.0266
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0049 0.0055 0.0163
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1363 0.2817 0.3491
Loa Loa (eye worm) hypothetical protein 0.0056 0.0069 0.0085
Entamoeba histolytica calmodulin, putative 0.02 0.0372 0.1298
Echinococcus granulosus calumenin 0.0204 0.0381 0.038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0015 0.0019
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3286 0.6861 0.686
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.011 0.011
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0215 0.0705
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0017 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0086 0.0106
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.012 0.0204 0.0253
Schistosoma mansoni cpg binding protein 0.0091 0.0144 0.0178
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0026 0.0064
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0056 0.0069 0.0085
Brugia malayi Cathepsin L-like precursor 0.0414 0.0823 0.102
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0076 0.011 0.0137
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0629 0.0772
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0054 0.0058
Trypanosoma brucei calpain-like protein, putative 0.1289 0.2662 0.7559
Schistosoma mansoni adenoreceptor 0.0076 0.011 0.0137
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1022 0.2101 0.5964
Echinococcus multilocularis peroxidasin 0.0107 0.0177 0.0176
Echinococcus multilocularis programmed cell death protein 0.0234 0.0444 0.0443
Brugia malayi hypothetical protein 0.004 0.0035 0.0044
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0156 0.028 0.0926
Onchocerca volvulus Putative cubilin 0.0031 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0015 0.0019
Plasmodium falciparum plasmepsin V 0.0051 0.0059 0.0185
Brugia malayi proteasome subunit alpha type 3 0.0026 0.0007 0.0009
Trichomonas vaginalis calpain, putative 0.0487 0.0975 0.3282
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0356 0.0355
Brugia malayi aspartic protease BmAsp-1, identical 0.0051 0.0059 0.0073
Echinococcus multilocularis GPCR, family 2 0.0031 0.0017 0.0016
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0755 0.1538 0.19
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0061 0.0194
Trypanosoma brucei cysteine peptidase, putative 0.0707 0.1438 0.4076
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.011 0.0137
Trypanosoma cruzi metacaspase, putative 0.0043 0.0042 0.0043
Echinococcus multilocularis cathepsin b 0.3859 0.8067 0.8067
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0159 0.0197
Giardia lamblia Programmed cell death protein-like protein 0.0034 0.0024 0.0056
Trypanosoma cruzi calmodulin, putative 0.02 0.0372 0.0453
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0162 0.0293 0.0292
Schistosoma mansoni caspase-3 (C14 family) 0.0114 0.0191 0.0236
Onchocerca volvulus 0.0057 0.0071 0.0191
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.011 0.011
Loa Loa (eye worm) calpain family protein 1 0.3086 0.644 0.7983
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Loa Loa (eye worm) hypothetical protein 0.0083 0.0126 0.0156
Echinococcus multilocularis Calcium binding protein 0.0034 0.0024 0.0023
Brugia malayi calpain 5 0.0802 0.1638 0.2031
Plasmodium falciparum plasmepsin IV 0.0162 0.0293 0.1018
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.034 0.0667 0.2348
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0233 0.0442 0.8882
Brugia malayi cathepsin Z-like cysteine proteinase 0.034 0.0667 0.0827
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0039 0.0087
Brugia malayi intermediate filament protein 0.0057 0.0071 0.0088
Onchocerca volvulus 0.1363 0.2817 0.7551
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Brugia malayi putative neuropeptide receptor 0.0076 0.011 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0703 0.236
Leishmania major receptor-type adenylate cyclase a-like protein 0.0221 0.0415 0.1163
Trichomonas vaginalis chromobox protein, putative 0.0042 0.004 0.0113
Onchocerca volvulus 0.0039 0.0032 0.0087
Trichomonas vaginalis calmodulin, putative 0.0204 0.0381 0.1268
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0042 0.0094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1429 0.2956 0.3664
Toxoplasma gondii calmodulin CAM1 0.0204 0.0381 0.1012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0096 0.1827
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Trypanosoma brucei protein I/6 0.02 0.0372 0.1039
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0134 0.0234 0.029
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0026 0.0007 0.0006
Trypanosoma cruzi calmodulin, putative 0.02 0.0372 0.0453
Onchocerca volvulus 0.0076 0.011 0.0296
Brugia malayi putative neuropeptide receptor NPR1 0.0076 0.011 0.0137
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0162 0.0293 0.0292
Brugia malayi aspartic protease BmAsp-2, identical 0.0051 0.0059 0.0073
Echinococcus multilocularis prefoldin subunit 6 0.0065 0.0088 0.0087
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Brugia malayi Thioredoxin reductase 0.0102 0.0166 0.0206
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0015 0.0019
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Trypanosoma brucei small myristoylated protein 1-1 0.0381 0.0752 0.212
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0469 0.0938 0.1163
Echinococcus multilocularis proteasome subunit beta type 6 0.0026 0.0007 0.0006
Toxoplasma gondii EFHC1, putative 0.02 0.0372 0.0987
Schistosoma mansoni neuropeptide receptor 0.0076 0.011 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.1163
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Brugia malayi cathepsin F-like cysteine proteinase 0.0414 0.0823 0.102
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0052 0.0129
Echinococcus multilocularis calmodulin 0.02 0.0372 0.0371
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Schistosoma mansoni centrin 0.02 0.0372 0.0461
Onchocerca volvulus 0.0031 0.0016 0.0043
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Echinococcus granulosus programmed cell death protein 6 0.0039 0.0033 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1363 0.2817 0.9529
Echinococcus granulosus neuropeptide FF receptor 2 0.0076 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0015 0.0019
Echinococcus granulosus carbonic anhydrase 0.0134 0.0234 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0415 0.0507
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.034 0.0667 0.0827
Echinococcus multilocularis geminin 0.0682 0.1386 0.1386
Brugia malayi beta-lactamase 0.0039 0.0032 0.004
Echinococcus multilocularis Mastin 0.008 0.0121 0.012
Trypanosoma cruzi cysteine peptidase, putative 0.1696 0.3519 0.4357
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0707 0.1438 0.1776
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0137 0.024 0.0297
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0079 0.0118 0.0117
Entamoeba histolytica cysteine proteinase, putative 0.0755 0.1538 0.545
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0034 0.0024 0.0063
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Echinococcus multilocularis chromobox protein 1 0.007 0.0099 0.0098
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0156 0.028 0.0347
Trichomonas vaginalis centrin, putative 0.02 0.0372 0.1237
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0032 0.0031
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0032 0.052
Echinococcus granulosus g protein coupled receptor 0.0076 0.011 0.011
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0034 0.0024 0.0063
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0019 0.0015
Plasmodium falciparum plasmepsin VI 0.0162 0.0293 0.1018
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0134 0.0234 0.029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0861 0.1761 0.2176
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0026 0.0051
Echinococcus granulosus cathepsin L 0.034 0.0667 0.0666
Onchocerca volvulus 0.0031 0.0016 0.0043
Schistosoma mansoni biogenic amine receptor 0.0076 0.011 0.0137
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0026 0.0007 0.0006
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Trypanosoma brucei Component of motile flagella 41 0.02 0.0372 0.1039
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0076 0.0095
Plasmodium falciparum serine repeat antigen 4 0.034 0.0667 0.2348
Trichomonas vaginalis calcineurin B subunit, putative 0.0204 0.0381 0.1268
Leishmania major DNA polymerase eta, putative 0.0034 0.0022 0.0043
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Onchocerca volvulus 0.0039 0.0032 0.0087
Entamoeba histolytica cysteine proteinase 2 0.0755 0.1538 0.545
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0016 0.002
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Mycobacterium tuberculosis Long conserved protein 0.0069 0.0096 0.1827
Echinococcus multilocularis g-protein coupled receptor 0.0076 0.011 0.011
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0032 0.052
Schistosoma mansoni hypothetical protein 0.0135 0.0235 0.0291
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.034 0.0667 0.0827
Entamoeba histolytica hypothetical protein, conserved 0.0204 0.0381 0.1331
Toxoplasma gondii calmodulin, putative 0.0034 0.0024 0.0045
Brugia malayi Trypsin family protein 0.008 0.0121 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1398 0.3962
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Trypanosoma cruzi unspecified product 0.0381 0.0752 0.0924
Echinococcus granulosus g protein coupled receptor 0.0076 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.034 0.0667 0.2238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Loa Loa (eye worm) myosin Light Chain family member 0.0039 0.0033 0.0041
Toxoplasma gondii centrin, putative 0.02 0.0372 0.0987
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0079 0.0118 0.0316
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0086 0.0106
Onchocerca volvulus 0.0034 0.0024 0.0063
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0026 0.0007 0.0006
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0049 0.0055 0.0068
Leishmania major hypothetical protein, unknown function 0.0487 0.0975 0.2755
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0061 0.0194
Schistosoma mansoni amine GPCR 0.0076 0.011 0.0137
Echinococcus granulosus proteasome subunit beta t family 0.0026 0.0007 0.0006
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0539 0.1516
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0019 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Leishmania major calcineurin B subunit, putative 0.02 0.0372 0.1039
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus calmodulin 0.02 0.0372 0.0371
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0076 0.011 0.0137
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0487 0.0975 0.2618
Echinococcus granulosus calpain A 0.1289 0.2662 0.2661
Brugia malayi Trypsin family protein 0.008 0.0121 0.0149
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0026 0.0064
Plasmodium falciparum plasmepsin X 0.0051 0.0059 0.0185
Toxoplasma gondii calcium binding egf domain-containing protein 0.0044 0.0044 0.0101
Echinococcus multilocularis g protein coupled receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0134 0.0234 0.029
Schistosoma mansoni cathepsin F (C01 family) 0.0948 0.1945 0.2411
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0076 0.011 0.011
Giardia lamblia Hypothetical protein 0.0204 0.0381 0.1268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0755 0.1538 0.4361
Echinococcus multilocularis Transglutaminase 0.0069 0.0096 0.0096
Trypanosoma brucei calpain, putative 0.0487 0.0975 0.2755
Echinococcus multilocularis fibrillin 1 0.0044 0.0044 0.0044
Plasmodium vivax proteasome subunit beta type-5, putative 0.0156 0.028 0.0972
Echinococcus multilocularis neurocalcin 0.02 0.0372 0.0371
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0076 0.011 0.0137
Loa Loa (eye worm) EF hand family protein 0.02 0.0372 0.0461
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0356 0.0441
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0109
Echinococcus granulosus G protein coupled receptor 139 0.0076 0.011 0.011
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0076 0.011 0.0137
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0016 0.0025
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0032 0.0089
Echinococcus granulosus dro:myosuppressin receptor 0.0076 0.011 0.011
Echinococcus multilocularis Tolloid protein 1 0.0137 0.024 0.0239
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Trypanosoma cruzi small myristoylated protein 1-1 0.0381 0.0752 0.0924
Echinococcus granulosus prefoldin subunit 6 0.0065 0.0088 0.0087
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0707 0.1438 0.1776
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0026 0.0007 0.0006
Mycobacterium ulcerans beta-lactamase 0.0039 0.0032 0.0933
Trichomonas vaginalis centrin, putative 0.0034 0.0024 0.0056
Brugia malayi Cytochrome P450 family protein 0.0049 0.0054 0.0067
Brugia malayi RNA binding protein 0.0064 0.0086 0.0106
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.02 0.0372 0.0453
Brugia malayi hypothetical protein 0.0052 0.0061 0.0076
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0221 0.0415 0.1163
Giardia lamblia Cathepsin B precursor 0.034 0.0667 0.2238
Schistosoma mansoni neuropeptide f receptor 76f 0.0076 0.011 0.0137
Brugia malayi Proteasome subunit alpha type 7-1 0.0026 0.0007 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0204 0.0381 0.1331
Loa Loa (eye worm) calpain family protein 1 0.2283 0.4753 0.5892
Leishmania major cathepsin L-like protease 0.1696 0.3519 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.1363 0.2817 0.2816
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0026 0.0007 0.0009
Echinococcus granulosus hypothetical protein 0.0076 0.011 0.011
Trypanosoma brucei metacaspase MCA3 0.0043 0.0042 0.0099
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0026 0.0692
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0076 0.0076
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0215 0.0266
Schistosoma mansoni rab 0.02 0.0372 0.0461
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Brugia malayi AKH receptor 0.0076 0.011 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0015 0.0019
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0476 0.059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0061 0.0079 0.0098
Brugia malayi RasGEF domain containing protein 0.0034 0.0024 0.0029
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0707 0.1438 0.4076
Onchocerca volvulus 0.0076 0.011 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0015 0.0019
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.052
Loa Loa (eye worm) hypothetical protein 0.0048 0.0052 0.0065
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0032 0.004
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0026 0.0007 0.0009
Echinococcus multilocularis dro:myosuppressin receptor 0.0076 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Echinococcus granulosus caspase 3 0.0071 0.01 0.01
Trichomonas vaginalis caltractin, putative 0.0034 0.0024 0.0056
Echinococcus multilocularis calmodulin 0.02 0.0372 0.0371
Brugia malayi proteasome subunit alpha type 1 0.0026 0.0007 0.0009
Plasmodium falciparum thioredoxin reductase 0.0102 0.0166 0.0567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Brugia malayi beta-lactamase family protein 0.0039 0.0032 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0026
Onchocerca volvulus 0.0031 0.0016 0.0043
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0671 0.1362 0.1688
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0015 0.0015
Loa Loa (eye worm) beta-lactamase 0.0039 0.0032 0.004
Echinococcus granulosus expressed protein 0.0362 0.0713 0.0713
Loa Loa (eye worm) hypothetical protein 0.0152 0.0271 0.0336
Toxoplasma gondii centrin family protein 0.0034 0.0024 0.0045
Brugia malayi Muscleblind-like protein 0.0152 0.0271 0.0336
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0016 0.0025
Trypanosoma cruzi centrin, putative 0.0234 0.0444 0.0542
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.011 0.0137
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0034 0.0024 0.0056
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0026 0.0067
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.011 0.011
Schistosoma mansoni amine GPCR 0.0076 0.011 0.0137
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0034 0.0024 0.0059
Schistosoma mansoni mitochondrial solute carrier 0.02 0.0372 0.0461
Toxoplasma gondii EF hand domain-containing protein 0.0034 0.0024 0.0045
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0013
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0026 0.0007 0.0006
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Toxoplasma gondii centrin 0.02 0.0372 0.0987
Trichomonas vaginalis calpain, putative 0.0487 0.0975 0.3282
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.011 0.011
Giardia lamblia Cathepsin B precursor 0.1429 0.2956 1
Echinococcus granulosus cathepsin L 0.0755 0.1538 0.1538
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0604 0.1221 0.1514
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0032 0.0086
Loa Loa (eye worm) RNA binding protein 0.0064 0.0086 0.0106
Schistosoma mansoni DNA polymerase eta 0.0048 0.0052 0.0065
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0248 0.0473 0.0578
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0019 0.0018
Echinococcus multilocularis cysteine protease 0.1363 0.2817 0.2816
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0026 0.0007 0.0009
Trichomonas vaginalis calmodulin, putative 0.02 0.0372 0.1237
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0076 0.142
Loa Loa (eye worm) hypothetical protein 0.0152 0.0271 0.0336
Leishmania major centrin, putative 0.02 0.0372 0.1039
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Mycobacterium ulcerans hydrolase 0.0028 0.0011 0.0132
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Schistosoma mansoni survival motor neuron protein 0.0096 0.0153 0.0189
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0076 0.011 0.011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0026 0.0054
Schistosoma mansoni calpain-7 (C02 family) 0.1289 0.2662 0.3299
Trypanosoma brucei cysteine peptidase C (CPC) 0.1429 0.2956 0.8396
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0248 0.0473 0.0586
Onchocerca volvulus Neuropeptide F receptor homolog 0.0076 0.011 0.0296
Echinococcus multilocularis dnaJ subfamily B 0.0807 0.1649 0.1648
Brugia malayi Kringle domain containing protein 0.0066 0.009 0.0112
Plasmodium falciparum prefoldin subunit 6, putative 0.0065 0.0088 0.0289
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0106 0.0173 0.0215
Echinococcus granulosus tissue type plasminogen activator 0.0066 0.009 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Loa Loa (eye worm) histone methyltransferase 0.003 0.0015 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1398 0.1726
Echinococcus granulosus glycoprotein Antigen 5 0.008 0.0121 0.012
Trichomonas vaginalis kakapo, putative 0.0034 0.0024 0.0056
Onchocerca volvulus 0.0066 0.009 0.0241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Echinococcus multilocularis lamin dm0 0.0057 0.0071 0.007
Plasmodium vivax unspecified product 0.034 0.0667 0.2348
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Echinococcus multilocularis carbonic anhydrase II 0.0248 0.0473 0.0472
Giardia lamblia Cysteine protease 0.034 0.0667 0.2238
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus granulosus cathepsin b 0.3859 0.8067 0.8067
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma cruzi cruzipain precursor, putative 0.1696 0.3519 0.4357
Brugia malayi Proteasome subunit alpha type 1 0.0026 0.0007 0.0009
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.149 0.3086 0.3819
Echinococcus granulosus cathepsin l1 0.1363 0.2817 0.2816
Echinococcus multilocularis calpain 7 (C02 family) 0.1289 0.2662 0.2661
Mycobacterium leprae Conserved hypothetical protein 0.0069 0.0096 0.1827
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Schistosoma mansoni hypothetical protein 0.0807 0.1649 0.2044
Brugia malayi Papain family cysteine protease containing protein 0.0755 0.1538 0.1907
Onchocerca volvulus 0.024 0.0456 0.1223
Echinococcus multilocularis programmed cell death protein 6 0.0039 0.0033 0.0032
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3086 0.644 0.7983
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0049 0.0055 0.013
Entamoeba histolytica cysteine proteinase, putative 0.0755 0.1538 0.545
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0093 0.0115
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0243 0.08
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0026 0.0007 0.0006
Onchocerca volvulus Cell death protein 3 homolog 0.0083 0.0126 0.0337
Schistosoma mansoni neuropeptide receptor 0.0076 0.011 0.0137
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.008 0.0121 0.0149
Leishmania major centrin, putative,caltractin, putative 0.02 0.0372 0.1039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0015 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.624
Brugia malayi EF hand family protein 0.02 0.0372 0.0461
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0032 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1363 0.2817 0.2816
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0026 0.0023
Schistosoma mansoni growth hormone secretagogue receptor 0.0076 0.011 0.0137
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0079 0.0118 0.0146
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0707 0.1438 0.1776
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0015 0.0019
Brugia malayi Heterochromatin protein 1 0.007 0.0099 0.0122
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1568 0.325 0.4023
Echinococcus granulosus Calcium binding protein 0.0034 0.0024 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0415 0.0507
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0015 0.0019
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0086 0.0106
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0231 0.0438 0.0543
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0086 0.0106
Schistosoma mansoni neuronal calcium sensor 0.02 0.0372 0.0461
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0487 0.0975 0.2755
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0026 1
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Brugia malayi Cathepsin L-like precursor 0.0948 0.1945 0.2411
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0826 0.1689 0.2087
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0084 0.0128 0.0127
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0235 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.011 0.011
Leishmania major cathepsin L-like protease 0.1363 0.2817 0.8
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0415 0.0507
Schistosoma mansoni centrin-related 0.02 0.0372 0.0461
Onchocerca volvulus 0.008 0.0121 0.0323
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0086 0.0106
Trypanosoma brucei antigen, putative 0.1289 0.2662 0.7559
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0039 0.0038
Plasmodium vivax unspecified product 0.0414 0.0823 0.2904
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.004 0.0108
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.0507
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0204 0.0381 0.0464
Mycobacterium ulcerans hypothetical protein 0.008 0.0121 0.416
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.034 0.0667 0.2238
Brugia malayi G-protein coupled receptor 0.0076 0.011 0.0137
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.034 0.0667 0.2348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Leishmania major hypothetical protein, conserved 0.0079 0.0118 0.0316
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Brugia malayi Fibulin-1 precursor 0.0044 0.0044 0.0055
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0149 0.0149
Leishmania major calpain protease-like protein 0.0487 0.0975 0.2755
Onchocerca volvulus 0.1797 0.373 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.2719
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.0149
Brugia malayi Serotonin receptor 0.0076 0.011 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.034 0.0667 0.2238
Leishmania major hypothetical protein, unknown function 0.0079 0.0118 0.0316
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.011 0.011
Schistosoma mansoni lamin 0.0057 0.0071 0.0088
Echinococcus granulosus neuronal calcium sensor 0.02 0.0372 0.0371
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis calcium binding protein, putative 0.0234 0.0444 0.1482
Onchocerca volvulus 0.008 0.0121 0.0323
Schistosoma mansoni caspase-7 (C14 family) 0.0083 0.0126 0.0156
Plasmodium vivax vivapain-3 0.0755 0.1538 0.545
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Loa Loa (eye worm) calpain 5 0.0802 0.1638 0.2031
Schistosoma mansoni chromatin regulatory protein sir2 0.0139 0.0243 0.0301
Echinococcus granulosus g protein coupled receptor 0.0076 0.011 0.011
Plasmodium falciparum serine repeat antigen 7 0.034 0.0667 0.2348
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0215 0.0214
Mycobacterium tuberculosis Conserved protein 0.0069 0.0096 0.1827
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.011 0.0137
Brugia malayi Dopamine receptor protein 1 0.0076 0.011 0.0137
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0707 0.1438 0.1776
Echinococcus granulosus dnaJ subfamily B 0.0807 0.1649 0.1648
Plasmodium vivax plasmepsin V, putative 0.0051 0.0059 0.0185
Brugia malayi hypothetical protein 0.008 0.0121 0.0149
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0162 0.0293 0.0774
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0019 0.0043
Echinococcus multilocularis glycoprotein Antigen 5 0.008 0.0121 0.012
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1568 0.325 0.9233
Trypanosoma brucei hypothetical protein, conserved 0.02 0.0372 0.1039
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0055 0.0068 0.0084
Plasmodium vivax vivapain-2 0.1363 0.2817 1
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Brugia malayi Serotonin receptor 0.0076 0.011 0.0137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0861 0.1761 0.4995
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0061 0.0194
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Echinococcus multilocularis caspase 3 0.0071 0.01 0.01
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0086
Brugia malayi hypothetical protein 0.0304 0.059 0.0732
Echinococcus multilocularis enteropeptidase 0.008 0.0121 0.012
Trypanosoma cruzi cruzipain precursor, putative 0.0414 0.0823 0.1012
Brugia malayi Trypsin-like protease protein 5 0.008 0.0121 0.0149
Brugia malayi neuropeptide F receptor 0.0076 0.011 0.0137
Onchocerca volvulus 0.0079 0.0118 0.0316
Loa Loa (eye worm) melatonin receptor type 1A 0.0076 0.011 0.0137
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0166 0.0567
Echinococcus granulosus orexin receptor type 2 0.0076 0.011 0.011
Plasmodium falciparum plasmepsin I 0.0162 0.0293 0.1018
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0039 0.0109
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.034 0.0667 0.0827
Trypanosoma brucei Calpain-like protein 1.2 0.0861 0.1761 0.4995
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1398 0.3962
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1022 0.2101 0.5964
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0114 0.0191 0.019
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.004 0.0035 0.0043
Brugia malayi Dopamine receptor protein 2 0.0076 0.011 0.0137
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1069 0.2198 0.2719
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0076 0.2545
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0061 0.0155
Entamoeba histolytica calmodulin, putative 0.02 0.0372 0.1298
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Loa Loa (eye worm) hypothetical protein 0.0123 0.021 0.026
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0215 0.0258
Echinococcus multilocularis calumenin 0.0204 0.0381 0.038
Leishmania major cathepsin L-like protease 0.1363 0.2817 0.8
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0019 0.0018
Giardia lamblia Transglutaminase/protease, putative 0.0069 0.0096 0.0303
Loa Loa (eye worm) hypothetical protein 0.004 0.0035 0.0043
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Onchocerca volvulus 0.0051 0.0059 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0215 0.0592
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.034 0.0667 0.2348
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0086 0.0106
Brugia malayi Peroxidasin 0.0107 0.0177 0.0219
Brugia malayi G protein-coupled receptor 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Onchocerca volvulus 0.0076 0.011 0.0296
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0019 0.0041
Trypanosoma brucei metacaspase 0.0043 0.0042 0.0099
Brugia malayi MH2 domain containing protein 0.0249 0.0476 0.059
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0054 0.0067
Entamoeba histolytica hypothetical protein 0.034 0.0667 0.2348
Loa Loa (eye worm) hypothetical protein 0.0039 0.0034 0.0042
Toxoplasma gondii hypothetical protein 0.0031 0.0016 0.0025
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0017 0.0021
Entamoeba histolytica prefoldin subunit 6, putative 0.0065 0.0088 0.0289
Onchocerca volvulus Cathepsin F homolog 0.1363 0.2817 0.7551
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0086 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0629 0.1772
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.034 0.0667 0.2348
Schistosoma mansoni myosin xvIII 0.0076 0.011 0.0137
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0004 0.0003
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0019 0.0248
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0099 0.0122
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0019 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0015 0.0019
Plasmodium falciparum glutathione reductase 0.0102 0.0166 0.0567
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Echinococcus multilocularis g protein coupled receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0094 0.0149 0.0185
Leishmania major calmodulin, putative 0.02 0.0372 0.1039
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.001
Echinococcus granulosus proteasome subunit beta type 6 0.0026 0.0007 0.0006
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0032 0.0032
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1568 0.325 0.4023
Onchocerca volvulus 0.0031 0.0016 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.1363 0.2817 0.3486
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0015 0.0015
Mycobacterium ulcerans hypothetical protein 0.0069 0.0096 0.3274
Loa Loa (eye worm) hypothetical protein 0.0051 0.0059 0.0073
Schistosoma mansoni hypothetical protein 0.0069 0.0096 0.012
Schistosoma mansoni calpain-2 (C02 family) 0.0487 0.0975 0.1208
Mycobacterium leprae Probable lipase LipE 0.0039 0.0032 0.052
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.011 0.011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0842 0.1721 0.4881
Mycobacterium ulcerans proteasome PrcB 0.0156 0.028 1
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.011 0.0137
Onchocerca volvulus 0.0076 0.011 0.0296
Brugia malayi ORL1-like opioid receptor 0.0076 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Schistosoma mansoni hypothetical protein 0.0134 0.0234 0.029
Loa Loa (eye worm) hypothetical protein 0.004 0.0035 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Schistosoma mansoni hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0034 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0086 0.0106
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0032 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.011 0.0137
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.034 0.0667 0.2348
Echinococcus granulosus subfamily T1A non peptidase ue 0.0026 0.0007 0.0006
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0049 0.0055 0.0068
Leishmania major metacaspase, putative 0.0043 0.0042 0.0099
Echinococcus granulosus Mastin 0.008 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0066 0.009 0.0112
Plasmodium falciparum plasmepsin III 0.0051 0.0059 0.0185
Brugia malayi neuropeptide F receptor 0.0076 0.011 0.0137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.624
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.3689 0.7709 0.9556
Schistosoma mansoni opsin-like receptor 0.0076 0.011 0.0137
Leishmania major cathepsin L-like protease 0.1363 0.2817 0.8
Echinococcus granulosus muscleblind protein 0.0152 0.0271 0.027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0356 0.0355
Brugia malayi Papain family cysteine protease containing protein 0.034 0.0667 0.0827
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.034 0.0667 0.0827
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0015 0.0019
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0015 0.0015
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.034 0.0667 0.2348
Leishmania major small myristoylated protein 4, putative 0.06 0.1213 0.3433
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0015 0.0019
Schistosoma mansoni cathepsin C 0.034 0.0667 0.0827
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0015 0.0019
Plasmodium falciparum metacaspase-like protein 0.0043 0.0042 0.0124
Echinococcus granulosus Proteasome subunit alpha beta 0.0026 0.0007 0.0006
Echinococcus multilocularis caspase 0.0114 0.0191 0.019
Schistosoma mansoni hypothetical protein 0.0076 0.011 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0015 0.0019
Plasmodium falciparum plasmepsin IX 0.0051 0.0059 0.0185
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.052
Trichomonas vaginalis calmodulin-2, putative 0.02 0.0372 0.1237
Brugia malayi Cytochrome P450 family protein 0.006 0.0078 0.0096
Schistosoma mansoni carbonic anhydrase 0.0134 0.0234 0.029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0149 0.0185
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.011 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis thyroid hormone receptor alpha 0.0165 0.0299 0.0298
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.02 0.0372 0.1298
Toxoplasma gondii cathepsin CPC1 0.034 0.0667 0.1785
Plasmodium falciparum centrin-1 0.02 0.0372 0.1298
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Echinococcus multilocularis tissue type plasminogen activator 0.0066 0.009 0.0089
Brugia malayi Animal haem peroxidase family protein 0.0107 0.0177 0.0219
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0826 0.1689 0.479
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0153 0.0189
Toxoplasma gondii preprocathepsin c precursor, putative 0.034 0.0667 0.1785
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0162 0.0293 0.0363
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0026 0.0007 0.0006
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0026 0.0067
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0032 0.052
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0015 0.0015
Trypanosoma cruzi centrin-3 0.0234 0.0444 0.0542
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Onchocerca volvulus 0.0034 0.0024 0.0063
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0019 0.0041
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0054 0.0067
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0019 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0032 0.0933
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0026 0.0007 0.0009
Brugia malayi Trypsin family protein 0.008 0.0121 0.0149
Schistosoma mansoni cathepsin D (A01 family) 0.0446 0.089 0.1103
Trypanosoma brucei caltractin, putative 0.0234 0.0444 0.1244
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0026 0.0067
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.034 0.0667 0.0827
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Echinococcus granulosus dna polymerase eta 0.0048 0.0052 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Brugia malayi cathepsin Z-like cysteine proteinase 0.034 0.0667 0.0827
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0015 0.0019
Onchocerca volvulus 0.0948 0.1945 0.5215
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0019 0.0043
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Loa Loa (eye worm) cathepsin B 0.1429 0.2956 0.3664
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Leishmania major cathepsin L-like protease 0.1696 0.3519 1
Onchocerca volvulus 0.1363 0.2817 0.7551
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0061 0.0068
Brugia malayi Proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0948 0.1945 0.2411
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0054 0.1714
Loa Loa (eye worm) hypothetical protein 0.0948 0.1945 0.2411
Brugia malayi follicle stimulating hormone receptor 0.0076 0.011 0.0137
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0078 0.0096
Trichomonas vaginalis calmodulin, putative 0.0234 0.0444 0.1482
Echinococcus granulosus cpg binding protein 0.0091 0.0144 0.0143
Echinococcus multilocularis G-protein coupled receptor, putative 0.0076 0.011 0.011
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.012 0.0204 0.0562
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0259 0.0496 1
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0079 0.0118 0.03
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0026 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.034 0.0667 0.2238
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0079 0.0118 0.03
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.2283 0.4753 0.5892
Loa Loa (eye worm) hypothetical protein 0.0034 0.0024 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0356 0.0355
Brugia malayi proteasome subunit alpha type 6 0.0026 0.0007 0.0009
Brugia malayi Eukaryotic aspartyl protease family protein 0.0051 0.0059 0.0073
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0026 0.0007 0.0009
Toxoplasma gondii thioredoxin reductase 0.0102 0.0166 0.0431
Echinococcus granulosus cysteine protease 0.0755 0.1538 0.1538
Plasmodium vivax proteasome subunit beta type-2, putative 0.0049 0.0055 0.0171
Schistosoma mansoni cathepsin B (C01 family) 0.034 0.0667 0.0827
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0079 0.0118 0.0138
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0032 0.0086
Brugia malayi Thioredoxin family protein 0.0069 0.0096 0.012
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0019 0.0033
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0134 0.0234 0.029
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.012 0.0204 0.0204
Echinococcus granulosus alpha 1A adrenergic receptor 0.0076 0.011 0.011
Onchocerca volvulus 0.0048 0.0052 0.014
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.008 0.0121 0.012
Plasmodium falciparum metacaspase 1 0.0043 0.0042 0.0124
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0009 0.0008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0145 0.018
Plasmodium falciparum proteasome subunit beta type-1, putative 0.012 0.0204 0.0702
Schistosoma mansoni calpain-7 (C02 family) 0.1289 0.2662 0.3299
Brugia malayi Cytochrome P450 family protein 0.0049 0.0054 0.0067
Echinococcus multilocularis g protein coupled receptor 0.0076 0.011 0.011
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0061 0.0147
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0015 0.0019
Brugia malayi hypothetical protein 0.0051 0.0059 0.0073
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Leishmania major proteasome beta 5 subunit, putative 0.0156 0.028 0.0778
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0051 0.0059 0.0141
Leishmania major hypothetical protein, conserved 0.02 0.0372 0.1039
Trypanosoma brucei calpain-like protein, putative 0.1568 0.325 0.9233
Leishmania major hypothetical protein, conserved 0.0052 0.0061 0.0155
Toxoplasma gondii EF hand domain-containing protein 0.02 0.0372 0.0987
Trypanosoma brucei proteasome beta 6 subunit 0.012 0.0204 0.0562
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0076 0.011 0.0137
Loa Loa (eye worm) AStacin protease 0.0086 0.0132 0.0163
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.034 0.0667 0.2238
Echinococcus granulosus tumor protein p63 0.0328 0.0641 0.064
Trypanosoma cruzi I/6 autoantigen, putative 0.02 0.0372 0.0453
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Schistosoma mansoni hypothetical protein 0.0065 0.0088 0.0109
Toxoplasma gondii cathepsin CPL 0.1363 0.2817 0.7603
Schistosoma mansoni opsin-like receptor 0.0076 0.011 0.0137
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0071 0.0088
Loa Loa (eye worm) proteasome subunit beta type 3 0.0026 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1429 0.2956 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0162 0.0293 0.0363
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.1784 0.3703 1
Echinococcus granulosus carbonic anhydrase 0.0134 0.0234 0.0233
Toxoplasma gondii hypothetical protein 0.0134 0.0234 0.0613
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.011 0.011
Brugia malayi TAR-binding protein 0.0064 0.0086 0.0106
Schistosoma mansoni cathepsin S (C01 family) 0.034 0.0667 0.0827
Brugia malayi Calmodulin-like protein 0.02 0.0372 0.0461
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0123 0.021 0.026
Trichomonas vaginalis conserved hypothetical protein 0.034 0.0667 0.2238
Echinococcus multilocularis calpain A 0.329 0.687 0.687
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0137 0.024 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0015 0.0019
Trypanosoma cruzi kinesin, putative 0.0802 0.1638 0.2024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0054
Echinococcus granulosus chromobox protein 1 0.007 0.0099 0.0098
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0019 0.0024
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.008 0.0121 0.0149
Giardia lamblia Cathepsin L-like protease 0.034 0.0667 0.2238
Loa Loa (eye worm) hypothetical protein 0.3086 0.644 0.7983
Entamoeba histolytica cysteine proteinase 1, putative 0.0755 0.1538 0.545
Echinococcus multilocularis cathepsin L cysteine protease 0.1363 0.2817 0.2816
Onchocerca volvulus 0.008 0.0121 0.0323
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0076 0.011 0.011
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Loa Loa (eye worm) proteasome subunit beta type 1 0.012 0.0204 0.0253
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0487 0.0975 0.3282
Echinococcus multilocularis lamin 0.0057 0.0071 0.007
Echinococcus granulosus fmrfamide receptor 0.0076 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0487 0.0975 0.3282
Echinococcus granulosus neuropeptide s receptor 0.0076 0.011 0.011
Onchocerca volvulus 0.0076 0.011 0.0296
Mycobacterium tuberculosis Hypothetical protein 0.0069 0.0096 0.1827
Trypanosoma brucei prefoldin subunit, putative 0.0065 0.0088 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.034 0.0667 0.2238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0015 0.0019
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0049 0.0055 0.0171
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0015 0.0019
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0539 0.1516
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0026 0.0007 0.0006
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.034 0.0667 0.2238
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0235 0.0234
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0233 0.0442 0.8882
Schistosoma mansoni calpain (C02 family) 0.1289 0.2662 0.3299
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0134 0.0234 0.029
Loa Loa (eye worm) hypothetical protein 0.0048 0.0052 0.0065
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Loa Loa (eye worm) PAS-3 protein 0.0026 0.0007 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0415 0.0507
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0707 0.1438 0.4076
Echinococcus granulosus lamin dm0 0.0057 0.0071 0.007
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0076 0.2545
Mycobacterium tuberculosis Conserved protein 0.0039 0.0032 0.052
Schistosoma mansoni neuropeptide receptor 0.0076 0.011 0.0137
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) calpain 0.1289 0.2662 0.3299
Echinococcus granulosus GPCR family 2 0.0031 0.0017 0.0016
Trypanosoma cruzi metacaspase, putative 0.0043 0.0042 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0149 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0149 0.0185
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.1163
Onchocerca volvulus 0.0031 0.0016 0.0043
Brugia malayi Papain family cysteine protease containing protein 0.034 0.0667 0.0827
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1069 0.2198 0.624
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0755 0.1538 0.1907
Brugia malayi hypothetical protein 0.0107 0.0177 0.0219
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0079 0.0118 0.0138
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0032 0.0032
Echinococcus granulosus calcyphosin protein 0.0034 0.0024 0.0023
Onchocerca volvulus 0.0107 0.0177 0.0474
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0248 0.0473 0.0586
Trypanosoma cruzi major cysteine proteinase, putative 0.0674 0.1369 0.169
Trypanosoma cruzi major cysteine proteinase, putative 0.034 0.0667 0.0819
Echinococcus multilocularis neuropeptide receptor A26 0.0076 0.011 0.011
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0629 0.1772
Echinococcus multilocularis caspase 2 0.0083 0.0126 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.011 0.011
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0015 0.0041
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0016 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Echinococcus multilocularis orexin receptor type 2 0.0076 0.011 0.011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1398 0.1726
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0015 0.0019
Echinococcus multilocularis G protein coupled receptor 139 0.0076 0.011 0.011
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0026 0.0007 0.0009
Brugia malayi calpain 7 0.1289 0.2662 0.3299
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0032 0.052
Brugia malayi Hemopexin family protein 0.0033 0.002 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0096 0.1827
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Brugia malayi Proteasome A-type and B-type family protein 0.0156 0.028 0.0347
Plasmodium falciparum glutathione reductase 0.0035 0.0026 0.0067
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0016 0.002
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Mycobacterium ulcerans transglutaminase family protein 0.0069 0.0096 0.3274
Trypanosoma brucei centrin-3 0.0234 0.0444 0.1244
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0034 0.0091
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0755 0.1538 0.1907
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Loa Loa (eye worm) hypothetical protein 0.034 0.0666 0.0825
Echinococcus granulosus Myosin regulatory light chain 0.0034 0.0024 0.0023
Onchocerca volvulus 0.0107 0.0177 0.0474
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0032 0.052
Echinococcus multilocularis neuropeptide receptor 0.0076 0.011 0.011
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0215 0.0705
Echinococcus multilocularis neuropeptide FF receptor 2 0.0076 0.011 0.011
Echinococcus multilocularis survival motor neuron protein 1 0.0469 0.0938 0.0937
Onchocerca volvulus 0.0107 0.0177 0.0474
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0215 0.0266
Echinococcus granulosus EF HAND 1 calcium binding site 0.02 0.0372 0.0371
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0019 0.0041
Brugia malayi beta-lactamase family protein 0.0039 0.0032 0.004
Onchocerca volvulus 0.004 0.0035 0.0095
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.034 0.0667 0.0827
Echinococcus granulosus cathepsin b 0.3859 0.8067 0.8067
Schistosoma mansoni neuronal calcium sensor 0.02 0.0372 0.0461
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.0149
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0021
Schistosoma mansoni calpain C (C02 family) 0.1289 0.2662 0.3299
Leishmania major calmodulin, putative 0.02 0.0372 0.1039
Plasmodium vivax unspecified product 0.0755 0.1538 0.545
Schistosoma mansoni cathepsin s 0.0414 0.0823 0.102
Toxoplasma gondii hypothetical protein 0.0031 0.0016 0.0025
Trypanosoma cruzi cysteine proteinase, putative 0.0755 0.1538 0.19
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis proteasome subunit alpha type 6 0.0026 0.0007 0.0006
Brugia malayi steroid hormone receptor 0.003 0.0015 0.0019
Echinococcus granulosus neuropeptide receptor A26 0.0076 0.011 0.011
Toxoplasma gondii cathepsin B 0.1429 0.2956 0.7979
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0259 0.0496 1
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0042 0.0043
Leishmania major proteasome beta 2 subunit, putative 0.0049 0.0055 0.0137
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0076 0.011 0.0137
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0059 0.0073
Echinococcus granulosus allatostatin A receptor 0.0076 0.011 0.011
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0026 0.0007 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0356 0.0355
Leishmania major META domain containing protein 0.0221 0.0415 0.1163
Entamoeba histolytica papain family cysteine protease domain containing protein 0.034 0.0667 0.2348
Loa Loa (eye worm) hypothetical protein 0.1797 0.373 0.4624
Toxoplasma gondii troponin c, isotype gamma, putative 0.02 0.0372 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118
Giardia lamblia Dipeptidyl-peptidase I precursor 0.034 0.0667 0.2238
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.0507
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.02 0.0372 0.0453
Trichomonas vaginalis calcium binding protein, putative 0.0034 0.0024 0.0056
Onchocerca volvulus Arrow homolog 0.004 0.0035 0.0094
Brugia malayi 20S proteasome alpha5 subunit 0.0026 0.0007 0.0009
Leishmania major i/6 autoantigen-like protein 0.02 0.0372 0.1039
Leishmania major cysteine peptidase A (CPA) 0.1363 0.2817 0.8
Giardia lamblia Hypothetical protein 0.0065 0.0088 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.0703 0.0863
Schistosoma mansoni hypothetical protein 0.0682 0.1386 0.1719
Leishmania major calpain family cysteine protease-like protein 0.0707 0.1438 0.4076
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Echinococcus multilocularis expressed protein 0.0362 0.0713 0.0713
Leishmania major hypothetical protein, conserved 0.0717 0.1458 0.4133
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.1163
Brugia malayi NAD-dependent deacetylase SIRT1 0.0139 0.0243 0.0301
Giardia lamblia Cathepsin B precursor 0.1429 0.2956 1
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0019 0.0043
Trichomonas vaginalis calmodulin, putative 0.0034 0.0024 0.0056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0621 0.1257 0.1551
Echinococcus multilocularis chromobox protein 1 0.007 0.0099 0.0098
Brugia malayi Proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Leishmania major small myristoylated protein-1 0.0381 0.0752 0.212
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0004 0.0003
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0166 0.0206
Trypanosoma brucei unspecified product 0.0221 0.0415 0.1163
Echinococcus granulosus carbonic anhydrase 0.0134 0.0234 0.0233
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.034 0.0667 0.2348
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0015 0.0019
Loa Loa (eye worm) sirtuin 4 0.0032 0.0019 0.0024
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.011 0.0137
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1429 0.2956 0.3658
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1363 0.2817 1
Trichomonas vaginalis calcium binding protein, putative 0.02 0.0372 0.1237
Leishmania major cathepsin L-like protease 0.1696 0.3519 1
Entamoeba histolytica cysteine protease, putative 0.1363 0.2817 1
Plasmodium falciparum thioredoxin reductase 0.0035 0.0026 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0755 0.1538 0.5194
Brugia malayi Animal haem peroxidase family protein 0.0107 0.0177 0.0219
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Echinococcus multilocularis serotonin receptor 0.0076 0.011 0.011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.0356 0.0441
Plasmodium falciparum cysteine proteinase falcipain 1 0.0755 0.1538 0.545
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.0149
Onchocerca volvulus 0.0057 0.0071 0.0191
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0026 0.0054
Echinococcus granulosus calpain 0.1289 0.2662 0.2661
Echinococcus granulosus proteasome subunit alpha type 2 0.0026 0.0007 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.1363 0.2817 0.3491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0038 0.0032 0.0071
Echinococcus granulosus calpain A 0.329 0.687 0.687
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0026 0.0007 0.0009
Echinococcus multilocularis cathepsin L 0.034 0.0667 0.0666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.012 0.0204 0.0245
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1363 0.2817 0.9529
Schistosoma mansoni coup transcription factor 0.003 0.0015 0.0019
Echinococcus multilocularis centrin 2 0.02 0.0372 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0024 0.0056
Echinococcus granulosus transmembrane protease serine 3 0.008 0.0121 0.012
Echinococcus multilocularis cathepsin L 0.0755 0.1538 0.1538
Echinococcus multilocularis EF hand domain containing family member A2 0.02 0.0372 0.0371
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1363 0.2817 0.3491
Brugia malayi ecdysteroid receptor 0.003 0.0015 0.0019
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1363 0.2817 0.2816
Entamoeba histolytica calpain large subunit domain III containing protein 0.0802 0.1638 0.5807
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0026 0.0023
Entamoeba histolytica papain family cysteine protease domain containing protein 0.034 0.0667 0.2348
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Onchocerca volvulus 0.0076 0.011 0.0296
Schistosoma mansoni reticulocalbin 0.02 0.0372 0.0461
Loa Loa (eye worm) blistered cuticle protein 3 0.0107 0.0177 0.0219
Schistosoma mansoni myosin light chain 0.0034 0.0024 0.0029
Trichomonas vaginalis myosin light chain 1, putative 0.02 0.0372 0.1237
Onchocerca volvulus Peroxidase homolog 0.0107 0.0177 0.0474
Echinococcus multilocularis tachykinin peptides receptor 99D 0.4778 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.011 0.011
Loa Loa (eye worm) DEAH box polypeptide 35 0.0033 0.0021 0.0026
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0026 0.0007 0.0009
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0766 0.1563 0.443
Brugia malayi glutathione reductase 0.0102 0.0166 0.0206
Loa Loa (eye worm) hypothetical protein 0.0052 0.0061 0.0076
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0149 0.0149
Onchocerca volvulus 0.0204 0.0381 0.1021
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0015 0.0019
Schistosoma mansoni cathepsin D (A01 family) 0.0446 0.089 0.1103
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0032 0.0933
Echinococcus granulosus chromobox protein 1 0.007 0.0099 0.0098
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Plasmodium vivax aspartyl proteinase, putative 0.0162 0.0293 0.1018
Onchocerca volvulus 0.1363 0.2817 0.7551
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.034 0.0667 0.0827
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0054 0.0133
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0017 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0054 0.0067
Onchocerca volvulus 0.0076 0.011 0.0296
Entamoeba histolytica cysteine proteinase, putative 0.0755 0.1538 0.545
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0049 0.0055 0.0137
Loa Loa (eye worm) calmodulin-like protein 0.02 0.0372 0.0461
Trypanosoma brucei centrin, putative 0.02 0.0372 0.1039
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0248 0.0473 0.0578
Onchocerca volvulus 0.0031 0.0016 0.0043
Toxoplasma gondii calcium binding protein precursor, putative 0.0034 0.0024 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0004 0.0003
Toxoplasma gondii kringle domain-containing protein 0.0066 0.009 0.0225
Onchocerca volvulus 0.1363 0.2817 0.7551
Schistosoma mansoni hypothetical protein 0.02 0.0372 0.0461
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Brugia malayi CXXC zinc finger family protein 0.0087 0.0133 0.0165
Echinococcus multilocularis carbonic anhydrase 0.0134 0.0234 0.0233
Trypanosoma brucei calpain, putative 0.0766 0.1563 0.443
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0049 0.0055 0.0171
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Echinococcus multilocularis cpg binding protein 0.0091 0.0144 0.0143
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0076 0.0198
Schistosoma mansoni histamine h1 receptor 0.0076 0.011 0.0137
Echinococcus multilocularis fmrfamide receptor 0.0076 0.011 0.011
Echinococcus multilocularis calpain family protein 1, d 0.2283 0.4753 0.4753
Echinococcus multilocularis sodium channel protein 0.0038 0.0032 0.0031
Onchocerca volvulus 0.0076 0.011 0.0296
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1289 0.2662 0.3294
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0032 0.052
Loa Loa (eye worm) hypothetical protein 0.008 0.0121 0.0149
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0231 0.0438 0.0543
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0006 0.0008
Schistosoma mansoni peroxidasin 0.0107 0.0177 0.0219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0009
Echinococcus granulosus calpain 7 C02 family 0.1289 0.2662 0.2661
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0026 0.0007 0.0006
Loa Loa (eye worm) matrixin family protein 0.0056 0.0069 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.034 0.0667 0.0827
Brugia malayi cathepsin F-like cysteine proteinase 0.034 0.0667 0.0827
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0629 0.0772
Trichomonas vaginalis set domain proteins, putative 0.0734 0.1495 0.5046
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0032 0.0084
Loa Loa (eye worm) hypothetical protein 0.0948 0.1945 0.2411
Giardia lamblia Cathepsin B precursor 0.034 0.0667 0.2238
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Onchocerca volvulus 0.0076 0.011 0.0296
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.0345 0.0427
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.012 0.0204 0.0245
Echinococcus multilocularis somatostatin receptor 0.0076 0.011 0.011
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0028 0.0011 0.0013
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0015 0.0014
Trypanosoma cruzi prefoldin subunit, putative 0.0065 0.0088 0.0101
Onchocerca volvulus 0.1363 0.2817 0.7551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.011 0.0137
Plasmodium falciparum plasmepsin VIII, putative 0.0051 0.0059 0.0185
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.028 0.0339
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.034 0.0667 0.2238
Echinococcus multilocularis cathepsin L cysteine protease 0.1363 0.2817 0.2816
Echinococcus granulosus sodium channel protein 0.0038 0.0032 0.0031
Loa Loa (eye worm) cysteine protease 0.1363 0.2817 0.3491
Entamoeba histolytica cysteine protease, putative 0.0755 0.1538 0.545
Brugia malayi Cathepsin L-like precursor 0.1363 0.2817 0.3491
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0042 0.0118
Giardia lamblia Cathepsin L-like protease 0.034 0.0667 0.2238
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0026 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Brugia malayi Neuronal calcium sensor family protein 1 0.0034 0.0024 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1696 0.3519 1
Echinococcus granulosus calbindin 32 0.0204 0.0381 0.038
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0019 0.0445
Schistosoma mansoni carbonic anhydrase-related 0.0134 0.0234 0.029
Loa Loa (eye worm) hypothetical protein 0.0414 0.0823 0.102
Giardia lamblia Hypothetical protein 0.0125 0.0215 0.0705
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118
Echinococcus granulosus somatostatin receptor 0.0076 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0017 0.0033
Schistosoma mansoni chromobox protein 0.007 0.0099 0.0122
Brugia malayi Animal haem peroxidase family protein 0.0107 0.0177 0.0219
Plasmodium falciparum serine repeat antigen 6 0.034 0.0667 0.2348
Trypanosoma cruzi cysteine peptidase, putative 0.0414 0.0823 0.1012
Entamoeba histolytica cysteine protease, putative 0.034 0.0667 0.2348
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0084 0.0128 0.0127
Mycobacterium leprae Conserved hypothetical protein 0.0069 0.0096 0.1827
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0024 0.0021
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.011 0.011
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0215 0.074
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Leishmania major carbonic anhydrase-like protein 0.0248 0.0473 0.1326
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0026 0.0007 0.0009
Echinococcus granulosus carbonic anhydrase II 0.0248 0.0473 0.0472
Plasmodium vivax metacaspase 1, putative 0.0043 0.0042 0.0124
Onchocerca volvulus 0.0033 0.002 0.0054
Toxoplasma gondii subtilisin SUB12 0.0031 0.0016 0.0025
Brugia malayi hypothetical protein 0.0076 0.011 0.0137
Giardia lamblia Encystation-specific protease 0.034 0.0667 0.2238
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0149 0.0385
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0356 0.0441
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.004 0.0035 0.0043
Loa Loa (eye worm) aspartyl protease 6 0.0051 0.0059 0.0073
Brugia malayi Calcium binding EGF domain containing protein 0.0044 0.0044 0.0055
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0233 0.0442 0.8882
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.001
Echinococcus multilocularis serotonin receptor 0.0076 0.011 0.011
Leishmania major programmed cell death 6 protein-like protein 0.02 0.0372 0.1039
Brugia malayi Calcium binding EGF domain containing protein 0.0031 0.0017 0.0021
Echinococcus multilocularis carbonic anhydrase 0.0134 0.0234 0.0233
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0076 0.011 0.011
Schistosoma mansoni Mername-AA248 (C02 family) 0.1289 0.2662 0.3299
Onchocerca volvulus 0.0106 0.0173 0.0465
Brugia malayi Pepsin A precursor 0.0051 0.0059 0.0073
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0076 0.011 0.0296
Brugia malayi Proteasome A-type and B-type family protein 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Onchocerca volvulus Dual oxidase homolog 0.0107 0.0177 0.0474
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.0149
Loa Loa (eye worm) animal heme peroxidase 0.0107 0.0177 0.0219
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0026 0.0032
Toxoplasma gondii prefoldin subunit 6, putative 0.0065 0.0088 0.022
Trypanosoma brucei metacaspase 5, putative 0.0043 0.0042 0.0099
Brugia malayi PAN domain containing protein 0.0031 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Schistosoma mansoni thyroid hormone receptor 0.0165 0.0299 0.037
Schistosoma mansoni carbonic anhydrase-related 0.0134 0.0234 0.029
Schistosoma mansoni neuronal calcium sensor 0.02 0.0372 0.0461
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0092 0.0145 0.018
Entamoeba histolytica cysteine proteinase, putative 0.0755 0.1538 0.545
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0019 0.0043
Mycobacterium ulcerans hypothetical protein 0.0069 0.0096 0.3274
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0015 0.0019
Brugia malayi calpain 5 0.0487 0.0975 0.1208
Onchocerca volvulus 0.0734 0.1496 0.401
Schistosoma mansoni hypothetical protein 0.0023 0.0001 0.0001
Entamoeba histolytica calcium binding family protein 0.02 0.0372 0.1298
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0042 0.0094
Schistosoma mansoni cercarial elastase (S01 family) 0.008 0.0121 0.0149
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0076 0.011 0.0137
Schistosoma mansoni amine GPCR 0.0076 0.011 0.0137
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0026 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.034 0.0667 0.2238
Plasmodium falciparum serine repeat antigen 1 0.034 0.0667 0.2348
Toxoplasma gondii hypothetical protein 0.0487 0.0975 0.2618
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0026 0.0007 0.0009
Trichomonas vaginalis calcineurin B subunit, putative 0.02 0.0372 0.1237
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Onchocerca volvulus 0.034 0.0667 0.1788
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0016 0.0025
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.028 0.0539 0.0661
Loa Loa (eye worm) programmed cell death protein 6 0.0204 0.0381 0.0472
Schistosoma mansoni memapsin-2 (A01 family) 0.0452 0.0902 0.1118
Echinococcus granulosus laminin 0.0044 0.0044 0.0044
Echinococcus granulosus EF hand domain containing family member A2 0.0204 0.0381 0.038
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0021
Toxoplasma gondii aspartyl protease ASP3 0.0051 0.0059 0.0141
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.025 0.031
Plasmodium falciparum serine repeat antigen 3 0.034 0.0667 0.2348
Entamoeba histolytica cysteine proteinase, putative 0.1363 0.2817 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0086
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0221 0.0415 0.0507
Entamoeba histolytica calmodulin, putative 0.0034 0.0024 0.0059
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0035 0.0035
Giardia lamblia Cathepsin L precursor 0.034 0.0667 0.2238
Loa Loa (eye worm) papain family cysteine protease containing protein 0.034 0.0667 0.0827
Giardia lamblia Hypothetical protein 0.034 0.0667 0.2238
Loa Loa (eye worm) animal heme peroxidase 0.0107 0.0177 0.0219
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0243 0.08
Loa Loa (eye worm) hypothetical protein 0.0057 0.0071 0.0088
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0414 0.0823 0.102
Onchocerca volvulus 0.0076 0.011 0.0296
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0026 0.0007 0.0009
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0415 0.1163
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3286 0.6861 0.686
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.02 0.0372 0.1039
Leishmania major hypothetical protein, conserved 0.0221 0.0415 0.1163
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0042 0.0124
Echinococcus granulosus intermediate filament protein 0.0057 0.0071 0.007
Echinococcus multilocularis EF hand domain containing family member A2 0.0204 0.0381 0.038
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0015 0.0015
Plasmodium vivax centrin-1, putative 0.02 0.0372 0.1298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0948 0.1945 0.6573
Leishmania major prefoldin subunit, putative 0.0065 0.0088 0.0231
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0026 0.0007 0.0009
Brugia malayi nuclear receptor NHR-88 0.003 0.0015 0.0019
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.008 0.0121 0.012
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0149 0.0149
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0019 0.0035
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0019 0.0024
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0243 0.08
Plasmodium vivax prefoldin subunit 6, putative 0.0065 0.0088 0.0289
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0016 0.0019
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0233 0.0442 0.8882
Loa Loa (eye worm) hypothetical protein 0.034 0.0667 0.0827
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118
Brugia malayi chromobox protein homolog 3 0.0039 0.0034 0.0042
Plasmodium vivax vivapain-1 0.0755 0.1538 0.545
Trypanosoma brucei Calpain-like protein 1.1 0.1069 0.2198 0.624
Schistosoma mansoni myosin regulatory light chain 0.0034 0.0024 0.0029
Trichomonas vaginalis calcium binding protein, putative 0.02 0.0372 0.1237
Loa Loa (eye worm) hypothetical protein 0.0107 0.0177 0.0219
Trypanosoma cruzi small myristoylated protein 1-2 0.0381 0.0752 0.0924
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0026 0.0054
Echinococcus granulosus caspase 0.0114 0.0191 0.019
Onchocerca volvulus Chorion peroxidase homolog 0.0107 0.0177 0.0474
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0052 0.0065
Brugia malayi nuclear hormone receptor 0.003 0.0015 0.0019
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0215 0.0266
Echinococcus granulosus sarcoplasmic calcium binding protein 0.02 0.0372 0.0371
Onchocerca volvulus 0.003 0.0015 0.0041
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0079 0.0118 0.0146
Brugia malayi calcium-binding protein 0.02 0.0372 0.0461
Plasmodium falciparum serine repeat antigen 8 0.034 0.0667 0.2348
Brugia malayi Melatonin receptor type 1A 0.0076 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118
Onchocerca volvulus Cathepsin L homolog 0.1363 0.2817 0.7551
Echinococcus granulosus cathepsin l1 0.0948 0.1945 0.1944
Trypanosoma cruzi cysteine peptidase, putative 0.0755 0.1538 0.19
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.02 0.0372 0.0453
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.011 0.0137
Plasmodium vivax aspartyl protease, putative 0.0051 0.0059 0.0185
Brugia malayi cathepsin B-like cysteine proteinase 0.3859 0.8067 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0026 0.0023
Toxoplasma gondii proteasome subunit beta type 1, putative 0.012 0.0204 0.0534
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0019
Echinococcus granulosus caspase 8 0.0043 0.0042 0.0041
Schistosoma mansoni dopamine-beta-monooxygenase 0.0123 0.021 0.026
Brugia malayi Probable ATP-dependent helicase DHX35 0.0033 0.0021 0.0026
Schistosoma mansoni myosin regulatory light chain 0.0034 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.0139 0.0243 0.0301
Loa Loa (eye worm) hypothetical protein 0.0039 0.0032 0.004
Brugia malayi hypothetical protein 0.013 0.0226 0.028
Echinococcus granulosus proteasome prosome macropain subunit beta 0.012 0.0204 0.0204
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0162 0.0293 0.097
Giardia lamblia Hypothetical protein 0.034 0.0667 0.2238
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Onchocerca volvulus 0.0039 0.0032 0.0087
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.06 0.1213 0.1496
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0079 0.0118 0.0146
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0076 0.2545
Loa Loa (eye worm) hypothetical protein 0.0076 0.011 0.0137
Brugia malayi prolyl 4-hydroxylase 0.0079 0.0118 0.0146
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0215 0.0266
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0032 0.052
Plasmodium vivax serine-repeat antigen (SERA), putative 0.034 0.0667 0.2348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trypanosoma cruzi cysteine peptidase, putative 0.1696 0.3519 0.4357
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.028 0.0539 0.1516
Mycobacterium tuberculosis Probable reductase 0.0233 0.0442 0.8882
Loa Loa (eye worm) hypothetical protein 0.0487 0.0975 0.1208
Schistosoma mansoni lamin 0.0057 0.0071 0.0088
Schistosoma mansoni cathepsin F (C01 family) 0.1363 0.2817 0.3491
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0242 0.0241
Onchocerca volvulus Cathepsin L homolog 0.034 0.0667 0.1788
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0139 0.0243 0.0242
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0959 0.1969 0.5587
Plasmodium vivax calpain, putative 0.1289 0.2662 0.9448
Brugia malayi Myosin regulatory light chain 1 0.0034 0.0024 0.0029
Echinococcus granulosus EF hand domain containing family member A2 0.02 0.0372 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1363 0.2817 0.9529
Trichomonas vaginalis centrin, putative 0.02 0.0372 0.1237
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0019 0.0043
Leishmania major small myristoylated protein-3, putative 0.0322 0.0629 0.1772
Schistosoma mansoni hypothetical protein 0.0067 0.0093 0.0115
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0539 0.1516
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0016 0.002
Echinococcus multilocularis calcium uptake protein 1 0.0204 0.0381 0.038
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0032 0.0086
Plasmodium falciparum plasmepsin II 0.0162 0.0293 0.1018
Trypanosoma brucei centrin, putative 0.02 0.0372 0.1039
Schistosoma mansoni hypothetical protein 0.0033 0.002 0.0025
Echinococcus granulosus Proteasome subunit alpha type 7 0.0026 0.0007 0.0006
Echinococcus granulosus calpain 5 0.1289 0.2662 0.2661
Toxoplasma gondii microneme protein MIC4 0.0031 0.0016 0.0025
Echinococcus granulosus enteropeptidase 0.008 0.0121 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0042 0.0118

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 5 mM The compound was evaluated for its binding affinity towards phosphotyrosine binding pocket of Src protein tryrosine kinase SH2 domain ChEMBL. 11965374
IC50 (binding) > 5 mM The compound was evaluated for its binding affinity towards phosphotyrosine binding pocket of Src protein tryrosine kinase SH2 domain ChEMBL. 11965374
IC50 (binding) = 5.44 uM Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow method ChEMBL. 22894736
IC50 (binding) = 6.08 uM Inhibition of human Carbonic anhydrase 9-mediated CO2 hydration by stopped-flow method ChEMBL. 22894736
IC50 (binding) = 7.68 uM Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method ChEMBL. 22894736
IC50 (binding) = 8 uM Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method ChEMBL. 22894736
IC50 (binding) = 20 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-2 was determined ChEMBL. 15139760
IC50 (binding) = 20 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-2 was determined ChEMBL. 15139760
IC50 (binding) = 20 uM Inhibition of MMP2 ChEMBL. 22894736
IC50 (binding) = 80 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-1 was determined ChEMBL. 15139760
IC50 (binding) = 80 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-1 was determined ChEMBL. 15139760
IC50 (binding) = 90 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-3 was determined ChEMBL. 15139760
IC50 (binding) = 90 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-3 was determined ChEMBL. 15139760
IC50 (binding) > 100 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-8 was determined ChEMBL. 15139760
IC50 (binding) > 100 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-9 was determined ChEMBL. 15139760
IC50 (binding) > 100 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-8 was determined ChEMBL. 15139760
IC50 (binding) > 100 uM In vitro inhibitory activity against recombinant matrix metalloproteinase-9 was determined ChEMBL. 15139760
Inhibition (functional) = 0 % In vitro inhibition of invasion of NIH 3T3 cells across the reconstituted basement membrane by the compound at 50 microM concentration in Boyden chamber chemoinvasion assay; Inactive ChEMBL. 15139760
Inhibition (functional) 0 % In vitro inhibition of endothelial capillary tube formation by the compound at 50 microM concentration; ND = No data ChEMBL. 15139760
Inhibition (functional) 0 % Inhibition of lung metastasis formation after 3 weeks treatment with 50 mg/kg of compound in mice injected with 50000 B16F10 tumor cells into the tail vein; ND = No data ChEMBL. 15139760

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.