Detailed information for compound 375863

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 394.457 | Formula: C19H21F3N4S
  • H donors: 3 H acceptors: 0 LogP: 4.7 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1c(C)[nH]c2c1/C(=N/NC(=S)Nc1ccc(cc1)C(F)(F)F)/CCC2
  • InChi: 1S/C19H21F3N4S/c1-3-14-11(2)23-15-5-4-6-16(17(14)15)25-26-18(27)24-13-9-7-12(8-10-13)19(20,21)22/h7-10,23H,3-6H2,1-2H3,(H2,24,26,27)/b25-16+
  • InChiKey: VYPSPAWIPXQIKG-PCLIKHOPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Niemann-Pick C1 protein precursor 0.0077 0.0211 0.0283
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0015 0.0009 0.0012
Onchocerca volvulus 0.0015 0.0009 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0043 0.0135
Leishmania major short chain dehydrogenase-like protein 0.0015 0.0009 0.0012
Plasmodium vivax telomerase reverse transcriptase, putative 0.084 0.2702 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.007 0.0133
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Brugia malayi Pre-SET motif family protein 0.0424 0.1345 0.1847
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.005 0.0122 0.0431
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Echinococcus granulosus o acyltransferase membrane bound domain 0.0158 0.0476 0.0907
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0029 0.0055 0.018
Echinococcus granulosus thyrotropin releasing hormone receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Leishmania major pteridine reductase 1 0.0015 0.0009 0.0012
Brugia malayi gonadotropin-releasing hormone receptor 2 0.003 0.0058 0.0073
Echinococcus multilocularis sterol O acyltransferase 1 0.1621 0.5252 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0113
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0015 0.0009 0.0007
Schistosoma mansoni thyroid hormone receptor 0.0034 0.007 0.0133
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0009 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0091 0.0238
Echinococcus granulosus heat shock protein 90 0.0029 0.0053 0.01
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0015 0.0009 0.0007
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0691
Schistosoma mansoni amine GPCR 0.003 0.0058 0.0111
Brugia malayi major facilitator superfamily protein 0.0014 0.0006 0.0001
Trypanosoma cruzi glycerol uptake protein, putative 0.0158 0.0476 0.1745
Echinococcus granulosus dro:myosuppressin receptor 0.003 0.0058 0.0111
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Loa Loa (eye worm) hypothetical protein 0.0195 0.0595 0.1132
Echinococcus granulosus dna polymerase kappa 0.004 0.0091 0.0173
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0107
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0015 0.0007 0.0014
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.007 0.0133
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0015 0.0009 0.0009
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0015 0.0009 0.0012
Echinococcus multilocularis transcription factor eb 0.0119 0.0348 0.0664
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0041 0.0133
Trypanosoma cruzi glycerol uptake protein, putative 0.0158 0.0476 0.1745
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0041 0.0099
Schistosoma mansoni biogenic amine (5HT) receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0041 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0041 0.0101
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0041 0.0133
Echinococcus granulosus g protein coupled receptor 0.003 0.0058 0.0111
Brugia malayi hypothetical protein 0.0443 0.1405 0.193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0011 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.007 0.0239
Schistosoma mansoni hypothetical protein 0.0025 0.0041 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0476 0.3071
Loa Loa (eye worm) RecQ helicase 0.0086 0.0239 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.007 0.0088
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0041 0.0101
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.003 0.0058 0.011
Onchocerca volvulus 0.003 0.0056 0.005
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0018 0.0033
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0015 0.0009 0.0012
Trichomonas vaginalis DNA helicase recq1, putative 0.0086 0.0239 0.1524
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0043 0.0137
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma brucei glycerol uptake protein, putative 0.0158 0.0476 0.1745
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Schistosoma mansoni carbonyl reductase 0.0015 0.0009 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0011 0.0022
Echinococcus granulosus heat shock protein 0.0036 0.0076 0.0146
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0062 0.0206
Brugia malayi hypothetical protein 0.0016 0.0011 0.0008
Entamoeba histolytica vacuolar protein sorting 26 0.0158 0.0476 0.3898
Trypanosoma brucei short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Echinococcus multilocularis protein dispatched 1 0.0064 0.0169 0.0322
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0015 0.0009 0.0007
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Echinococcus granulosus alpha 1A adrenergic receptor 0.003 0.0058 0.0111
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0077
Loa Loa (eye worm) hypothetical protein 0.0028 0.005 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0033
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.007 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0015 0.0009 0.0009
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0015 0.0009 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.005 0.0163
Loa Loa (eye worm) endoplasmin 0.0036 0.0076 0.0145
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0015 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.006 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0015 0.0009 0.0009
Schistosoma mansoni retinal dehydrogenase 0.0015 0.0009 0.0017
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0015 0.0009 0.0017
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.003 0.0058 0.011
Plasmodium vivax heat shock protein, putative 0.0015 0.0007 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.1621 0.5252 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0076 0.026
Schistosoma mansoni hypothetical protein 0.0049 0.012 0.0228
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.007 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Trypanosoma cruzi heat shock protein 90, putative 0.0029 0.0053 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0059 0.0197
Echinococcus granulosus sex peptide receptor 0.003 0.0058 0.0111
Echinococcus granulosus orexin receptor type 2 0.003 0.0058 0.0111
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0091 0.0316
Schistosoma mansoni zinc finger protein 0.0016 0.0011 0.0022
Echinococcus multilocularis g protein coupled receptor 0.003 0.0058 0.0111
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0015 0.0009 0.0017
Plasmodium vivax heat shock protein 90, putative 0.0015 0.0007 0.0004
Brugia malayi Sugar transporter family protein 0.0014 0.0006 0.0001
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0006 0.0012
Schistosoma mansoni peptide (allatostatin)-like receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0041 0.0101
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0041 0.0133
Loa Loa (eye worm) sugar transporter 0.0103 0.0294 0.0559
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0063 0.0213
Loa Loa (eye worm) G-protein coupled receptor 0.003 0.0058 0.011
Echinococcus granulosus g-protein coupled receptor 0.003 0.0058 0.0111
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0016 0.0031
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.012 0.0227
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0012
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0006 0.0012
Onchocerca volvulus 0.003 0.0058 0.0052
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0158 0.0476 0.0907
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0034 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Brugia malayi nuclear receptor RXR 0.0018 0.0018 0.0016
Trypanosoma cruzi Heat shock protein 83, putative 0.0036 0.0076 0.0263
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.007 0.0133
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.007 0.0133
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Brugia malayi Sugar transporter family protein 0.0014 0.0006 0.0001
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.0467 0.0636
Echinococcus multilocularis protein patched 0.0056 0.0143 0.0273
Brugia malayi heat shock protein 90 0.0036 0.0076 0.0098
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Schistosoma mansoni heat shock protein 0.0036 0.0076 0.0146
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0011 0.0022
Entamoeba histolytica hypothetical protein 0.0015 0.0009 0.0026
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0011 0.0008
Brugia malayi G protein-coupled receptor 0.003 0.0058 0.0073
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0896 0.33
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0016 0.0031
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus multilocularis geminin 0.0519 0.1654 0.315
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Brugia malayi Retinol dehydrogenase 12 0.0015 0.0009 0.0004
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0041 0.0099
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.0467 0.0636
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0025
Mycobacterium tuberculosis Possible oxidoreductase 0.0015 0.0009 0.0009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.003 0.0058 0.0111
Schistosoma mansoni neuropeptide F-like receptor 0.003 0.0058 0.0111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Brugia malayi dehydrogenases, short chain protein 2 0.0015 0.0009 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0006 0.0012
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0015 0.0009 0.0012
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.007 0.0063
Echinococcus granulosus retinol dehydrogenase 11 0.0015 0.0009 0.0017
Schistosoma mansoni glucose transporter 0.0014 0.0006 0.0012
Echinococcus multilocularis solute carrier family 22 0.0014 0.0006 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0049 0.012 0.0228
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.003 0.0058 0.0111
Echinococcus granulosus transcription factor eb 0.0119 0.0348 0.0664
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0158 0.0476 0.0906
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0011 0.0008
Echinococcus granulosus GPCR family 2 0.0049 0.012 0.0228
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Onchocerca volvulus 0.003 0.0058 0.0052
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Schistosoma mansoni cytochrome P450 0.0025 0.0041 0.0079
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Echinococcus multilocularis musashi 0.003 0.0056 0.0108
Leishmania major short chain dehydrogenase/reductase, putative 0.0015 0.0009 0.0012
Leishmania major 3-keto-dihydrosphingosine reductase 0.0015 0.0009 0.0012
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0158 0.0476 0.0907
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.028 0.0379
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0015 0.0009 0.0026
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.007 0.0063
Echinococcus multilocularis oxidoreductase 0.0015 0.0009 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0006 0.0011
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0041 0.0099
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Leishmania major cytochrome p450-like protein 0.0034 0.007 0.0239
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Leishmania major cytochrome p450-like protein 0.0025 0.0041 0.0133
Trypanosoma brucei short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.007 0.0133
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0062 0.0117
Entamoeba histolytica protein kinase, putative 0.0031 0.0062 0.0465
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.007 0.0133
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0112 0.0396
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0158 0.0476 0.3898
Schistosoma mansoni sugar transporter 0.0014 0.0006 0.0012
Toxoplasma gondii heat shock protein HSP90 0.0036 0.0076 0.026
Echinococcus granulosus ATP dependent DNA helicase Q5 0.006 0.0154 0.0294
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Leishmania major glycerol uptake protein, putative 0.0158 0.0476 0.1745
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0006 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Toxoplasma gondii heat shock protein 75, putative 0.0015 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0384 0.1213 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0059 0.0197
Schistosoma mansoni heat shock protein 0.0015 0.0007 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Trypanosoma brucei glycerol uptake protein, putative 0.0158 0.0476 0.1745
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0016 0.0039
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0034 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Entamoeba histolytica hypothetical protein 0.0109 0.0316 0.257
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0023 0.0342
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0076 0.026
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.003 0.0058 0.0111
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.007 0.0133
Brugia malayi nuclear hormone receptor 0.0016 0.0011 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0006 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0062 0.0208
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0041 0.0101
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Leishmania major short chain dehydrogenase/reductase, putative 0.0015 0.0009 0.0012
Echinococcus granulosus o acyltransferase membrane bound domain 0.0158 0.0476 0.0907
Giardia lamblia DNA repair protein RAD52 0.0384 0.1213 0.4477
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0011 0.0022
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0166 0.05 0.1833
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.007 0.0133
Leishmania major protein kinase, putative 0.0031 0.0062 0.0208
Echinococcus granulosus hypothetical protein 0.003 0.0058 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Brugia malayi GnHR receptor homolog 0.003 0.0058 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0041 0.0101
Echinococcus multilocularis neuropeptide Y receptor 0.003 0.0058 0.0111
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0062 0.0206
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.006 0.0114
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Mycobacterium ulcerans short-chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0156 0.047 0.0894
Onchocerca volvulus 0.0015 0.0009 0.0002
Schistosoma mansoni alpha-1 adrenergic receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus multilocularis neuropeptide receptor A26 0.1428 0.4623 0.8803
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0063 0.0371
Entamoeba histolytica protein kinase, putative 0.0031 0.0062 0.0465
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Giardia lamblia Sgs1 DNA helicase, putative 0.006 0.0154 0.0549
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0055 0.0106
Echinococcus multilocularis heat shock protein 90 0.0029 0.0053 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.005 0.0163
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0089 0.0169
Toxoplasma gondii hypothetical protein 0.0158 0.0476 0.1743
Trypanosoma brucei oxidoreductase-like protein 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Entamoeba histolytica short chain dehydrogenase family protein 0.0015 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.006 0.0114
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0498 0.0948
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0041 0.0101
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.084 0.2702 1
Echinococcus granulosus carbonyl reductase 1 0.0015 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0061 0.0158 0.03
Echinococcus multilocularis fmrfamide receptor 0.003 0.0058 0.0111
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0158 0.0476 0.0907
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni DNA polymerase eta 0.0014 0.0006 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) cytochrome P450 0.0025 0.0041 0.0078
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.007 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Trypanosoma brucei heat shock protein 90, putative 0.0036 0.0076 0.0263
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0015 0.0009 0.0012
Echinococcus multilocularis expressed conserved protein 0.0069 0.0185 0.0351
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0034 0.0078
Brugia malayi MBOAT family protein 0.0158 0.0476 0.0649
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0006 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0069 0.0185 0.0351
Brugia malayi MBOAT family protein 0.0158 0.0476 0.0649
Mycobacterium ulcerans short chain dehydrogenase 0.1099 0.355 1
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Echinococcus multilocularis g-protein coupled receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0015 0.0009 0.0009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0896 0.7372
Echinococcus granulosus steroid dehydrogenase 0.0015 0.0009 0.0017
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0158 0.0476 0.1743
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0029 0.0053 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) CYP4Cod1 0.0034 0.007 0.0133
Onchocerca volvulus 0.0016 0.0011 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.005 0.0165
Echinococcus multilocularis allatostatin A receptor 0.003 0.0058 0.0111
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0006 0.0011
Echinococcus granulosus neuropeptide Y receptor 0.003 0.0058 0.0111
Schistosoma mansoni nuclear receptor 0.0016 0.0011 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0158 0.0301
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0015 0.0009 0.0017
Leishmania major telomerase reverse transcriptase, putative 0.084 0.2702 1
Loa Loa (eye worm) neuropeptide F receptor 0.003 0.0058 0.011
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Entamoeba histolytica heat shock protein 90, putative 0.0036 0.0076 0.0587
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0476 0.3071
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0062 0.0206
Echinococcus multilocularis biogenic amine (5HT) receptor 0.003 0.0058 0.0111
Giardia lamblia Grp94/Hsp90 0.0029 0.0053 0.0172
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0063 0.0371
Schistosoma mansoni zinc finger protein 0.0158 0.0476 0.0907
Trypanosoma brucei short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0124 0.0164
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.007 0.0133
Echinococcus granulosus dna polymerase eta 0.0014 0.0006 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Onchocerca volvulus 0.0015 0.0009 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.003 0.0058 0.0111
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.012 0.0228
Mycobacterium ulcerans short-chain type oxidoreductase 0.0015 0.0009 0.0007
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0076 0.0263
Echinococcus multilocularis neuropeptide receptor 0.003 0.0058 0.0111
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0018 0.0033
Onchocerca volvulus 0.003 0.0058 0.0052
Echinococcus granulosus neuropeptide receptor 0.003 0.0058 0.0111
Trypanosoma cruzi short chain dehydrogenase, putative 0.0015 0.0009 0.0012
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0015 0.0009 0.0017
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.1048 0.3868
Trichomonas vaginalis set domain proteins, putative 0.0483 0.1536 1
Brugia malayi Hhat protein 0.0158 0.0476 0.0649
Brugia malayi neuropeptide F receptor 0.003 0.0058 0.0073
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0015 0.0009 0.0009
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Plasmodium falciparum steroid dehydrogenase, putative 0.0015 0.0009 0.0009
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.007 0.0132
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Echinococcus multilocularis solute carrier family 22 0.0014 0.0006 0.0012
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0015 0.0009 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0124 0.0236
Mycobacterium ulcerans dehydrogenase/reductase 0.0015 0.0009 0.0007
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0062 0.0206
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0076 0.0262
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0091 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.007 0.0132
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0041 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0059 0.0197
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0158 0.0476 0.0907
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0007 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0076 0.0263
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.012 0.0227
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0034 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.007 0.0088
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Echinococcus multilocularis neuropeptides capa receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Echinococcus granulosus carbonyl reductase 1 0.0015 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.006 0.0154 0.0293
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus multilocularis retinol dehydrogenase 13 0.0015 0.0009 0.0017
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Schistosoma mansoni endoplasmin 0.0036 0.0076 0.0146
Schistosoma mansoni growth hormone secretagogue receptor 0.003 0.0058 0.0111
Schistosoma mansoni carbonyl reductase 0.0015 0.0009 0.0017
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0063 0.0371
Onchocerca volvulus 0.0015 0.0009 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Brugia malayi hypothetical protein 0.004 0.0089 0.0115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Mycobacterium ulcerans short-chain dehydrogenase 0.0015 0.0009 0.0007
Schistosoma mansoni sugar transporter 0.0014 0.0006 0.0012
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0031
Schistosoma mansoni amine GPCR 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Echinococcus granulosus carbonyl reductase 1 0.0015 0.0009 0.0017
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0009
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0015 0.0009 0.0017
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.003 0.0058 0.0111
Schistosoma mansoni flap endonuclease-1 0.0023 0.0035 0.0066
Onchocerca volvulus 0.0015 0.0009 0.0002
Brugia malayi MH2 domain containing protein 0.0132 0.039 0.053
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0691
Trypanosoma brucei short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Brugia malayi Dehydrogenases, short chain protein 2 0.0015 0.0009 0.0004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.003 0.0058 0.0111
Echinococcus granulosus g protein coupled receptor 0.003 0.0058 0.0111
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0011 0.0005
Brugia malayi polk-prov protein 0.003 0.0059 0.0073
Trypanosoma cruzi heat shock protein, putative 0.0015 0.0007 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus granulosus G protein coupled receptor 139 0.003 0.0058 0.0111
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Treponema pallidum ATP-dependent DNA helicase 0.003 0.0059 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0076 0.0262
Toxoplasma gondii hypothetical protein 0.0054 0.0135 0.0477
Brugia malayi AKH receptor 0.003 0.0058 0.0073
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0006 0.0002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Giardia lamblia Hypothetical protein 0.0015 0.0009 0.0009
Schistosoma mansoni lamin 0.003 0.0056 0.0108
Loa Loa (eye worm) hypothetical protein 0.0443 0.1405 0.2675
Brugia malayi Hsp90 protein 0.0015 0.0007 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.003 0.0058 0.0111
Schistosoma mansoni neuropeptide F-like receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Brugia malayi G protein-coupled receptor F59B2.13 0.003 0.0058 0.0073
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0015 0.0009 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.007 0.0133
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.0009 0.0009
Schistosoma mansoni opsin-like receptor 0.003 0.0058 0.0111
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Trypanosoma cruzi heat shock protein 90, putative 0.0036 0.0076 0.0263
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.007 0.0133
Brugia malayi cytochrome P450 0.0025 0.0041 0.0049
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Echinococcus granulosus Protein patched homolog 1 0.0056 0.0143 0.0273
Schistosoma mansoni hypothetical protein 0.0049 0.012 0.0228
Echinococcus multilocularis somatostatin receptor 0.003 0.0058 0.0111
Toxoplasma gondii protein kinase, putative 0.029 0.0905 0.3335
Brugia malayi ecdysone receptor 0.0016 0.0011 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.007 0.0088
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0039
Brugia malayi putative neuropeptide receptor 0.003 0.0058 0.0073
Loa Loa (eye worm) DR-78 0.0016 0.0011 0.0021
Echinococcus multilocularis serotonin receptor 0.003 0.0058 0.0111
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0015 0.0009 0.0012
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0158 0.0476 0.0907
Plasmodium falciparum endoplasmin, putative 0.0022 0.0031 0.0092
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0043 0.0137
Schistosoma mansoni adenoreceptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0015 0.0009 0.0009
Schistosoma mansoni patched 1 0.0056 0.0143 0.0273
Brugia malayi Cytochrome P450 family protein 0.0034 0.007 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Trichomonas vaginalis DNA helicase recq, putative 0.0086 0.0239 0.1524
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus granulosus allatostatin A receptor 0.003 0.0058 0.0111
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) dehydrogenase 0.0015 0.0009 0.0016
Toxoplasma gondii oxidoreductase, putative 0.0015 0.0009 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.003 0.0058 0.011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0041 0.0101
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Trypanosoma brucei short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Leishmania major short chain dehydrogenase, putative 0.0015 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0106 0.0306 0.0583
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0091 0.0238
Onchocerca volvulus 0.0015 0.0009 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0158 0.0301
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0691
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.007 0.0133
Onchocerca volvulus 0.0015 0.0009 0.0002
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0065 0.0172 0.0616
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0034 0.0103
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0089 0.0169
Schistosoma mansoni hypothetical protein 0.0519 0.1654 0.315
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0015 0.0009 0.0017
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0015 0.0009 0.0009
Giardia lamblia Heat shock protein HSP 90-alpha 0.0029 0.0053 0.0172
Schistosoma mansoni neuropeptide receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0041 0.0099
Mycobacterium tuberculosis Probable oxidoreductase 0.1099 0.355 1
Trypanosoma brucei heat shock protein 84, putative 0.0015 0.0007 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0124 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.003 0.0058 0.0111
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Brugia malayi larval opioid receptor 0.003 0.0058 0.0073
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0166 0.05 0.1833
Brugia malayi G-protein coupled receptor 0.003 0.0058 0.0073
Plasmodium vivax endoplasmin, putative 0.0036 0.0076 0.026
Brugia malayi Melatonin receptor type 1A 0.003 0.0058 0.0073
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0011 0.0022
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0158 0.0476 0.0907
Echinococcus multilocularis carbonyl reductase 1 0.0015 0.0009 0.0017
Entamoeba histolytica heat shock protein 90, putative 0.0036 0.0076 0.0587
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0062 0.0206
Trypanosoma brucei cytochrome P450, putative 0.0034 0.007 0.0239
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.006 0.1248
Schistosoma mansoni sterol O-acyltransferase 1 0.1621 0.5252 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0112 0.0396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.0106 0.0306 0.0582
Schistosoma mansoni coup transcription factor 0.0034 0.007 0.0133
Echinococcus granulosus tm gpcr rhodopsin 0.003 0.0058 0.0111
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Echinococcus granulosus ATP dependent DNA helicase Q1 0.006 0.0154 0.0294
Brugia malayi G-protein coupled receptor 0.003 0.0058 0.0073
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0041 0.0101
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0158 0.0476 0.0907
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0015 0.0009 0.0017
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Brugia malayi hypothetical protein 0.0028 0.005 0.0061
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0007 0.0004
Toxoplasma gondii RNA-directed DNA polymerase 0.084 0.2702 1
Echinococcus granulosus neuropeptide receptor 0.003 0.0058 0.0111
Brugia malayi Dopamine receptor protein 1 0.003 0.0058 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.003 0.0058 0.0111
Onchocerca volvulus 0.0015 0.0009 0.0002
Trichomonas vaginalis porcupine, putative 0.0158 0.0476 0.3071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0033
Onchocerca volvulus 0.003 0.0058 0.0052
Onchocerca volvulus 0.0016 0.0011 0.0005
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0015 0.0009 0.0002
Echinococcus multilocularis 0.0025 0.0041 0.0079
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0029 0.0053 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0015 0.0009 0.0007
Onchocerca volvulus 0.003 0.0058 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Entamoeba histolytica hypothetical protein, conserved 0.0158 0.0476 0.3898
Onchocerca volvulus 0.003 0.0058 0.0052
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Schistosoma mansoni sugar transporter 0.0014 0.0006 0.0012
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0015 0.0009 0.0017
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.006 0.0075
Brugia malayi ORL1-like opioid receptor 0.003 0.0058 0.0073
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0065 0.0172 0.0616
Brugia malayi hypothetical protein 0.0018 0.0018 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.1345 0.256
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni biogenic amine receptor 0.003 0.0058 0.0111
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0158 0.0476 0.0907
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0012
Giardia lamblia Short-chain dehydrogenase, putative 0.0015 0.0009 0.0009
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.0041 0.0801
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.0009 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0124 0.0236
Echinococcus granulosus hypothetical protein 0.0015 0.0009 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Brugia malayi Dopamine receptor protein 2 0.003 0.0058 0.0073
Giardia lamblia Reductase, putative 0.0015 0.0009 0.0009
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0158 0.0563
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Echinococcus granulosus biogenic amine 5HT receptor 0.003 0.0058 0.0111
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0016 0.0037
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0016 0.0037
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0007 0.0004
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0011 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0062 0.0206
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0041 0.0099
Schistosoma mansoni neuropeptide receptor 0.003 0.0058 0.0111
Echinococcus granulosus neuropeptide s receptor 0.1428 0.4623 0.8803
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0158 0.0301
Loa Loa (eye worm) hypothetical protein 0.0158 0.0476 0.0906
Echinococcus multilocularis lamin 0.003 0.0056 0.0108
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0158 0.0476 0.0907
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.0533 0.1488
Giardia lamblia Heat shock protein HSP 90-alpha 0.0036 0.0076 0.026
Toxoplasma gondii oxidoreductase, putative 0.0015 0.0009 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Schistosoma mansoni biogenic amine receptor 0.003 0.0058 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Onchocerca volvulus 0.003 0.0058 0.0052
Treponema pallidum alginate O-acetylation protein (algI) 0.0158 0.0476 0.5024
Schistosoma mansoni biogenic amine (5HT) receptor 0.003 0.0058 0.0111
Schistosoma mansoni glucose transport protein 0.0103 0.0294 0.056
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0296 0.0562
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0109 0.0316 0.257
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Schistosoma mansoni biogenic amine receptor 0.003 0.0058 0.0111
Brugia malayi Dehydrogenases, short chain protein 30 0.0015 0.0009 0.0004
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0041 0.0099
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi hypothetical protein 0.0015 0.0009 0.0004
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0041 0.0099
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0056 0.007
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0113
Echinococcus granulosus flap endonuclease 1 0.0026 0.0043 0.0081
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0034 0.0065
Toxoplasma gondii carbonyl reductase 1, putative 0.0015 0.0009 0.0009
Echinococcus granulosus neuropeptide Y receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.007 0.0132
Echinococcus granulosus heat shock protein 90 0.0036 0.0076 0.0146
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0896 0.7372
Brugia malayi nuclear receptor NHR-88 0.0034 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) ATP-dependent DNA helicase 0.006 0.0154 0.0293
Echinococcus multilocularis tachykinin peptides receptor 99D 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.0009 0.0009
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.003 0.0058 0.0111
Brugia malayi conserved hypotetical protein 0.0016 0.0011 0.0008
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0056 0.0143 0.0272
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0154 0.0549
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.1462 0.4735 0.9016
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.007 0.0239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Echinococcus multilocularis dna polymerase kappa 0.004 0.0091 0.0173
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.003 0.0058 0.0111
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Onchocerca volvulus 0.0158 0.0476 0.047
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Giardia lamblia Telomerase catalytic subunit 0.084 0.2702 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0041 0.0099
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.012 0.0228
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0029 0.0053 0.01
Loa Loa (eye worm) intermediate filament protein 0.003 0.0056 0.0107
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0015 0.0009 0.0004
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0294 0.1068
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Echinococcus granulosus expressed conserved protein 0.0069 0.0185 0.0351
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.007 0.0238
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0158 0.0476 0.0907
Schistosoma mansoni hypothetical protein 0.0049 0.012 0.0228
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0025 0.0121
Entamoeba histolytica recQ family helicase, putative 0.0029 0.0055 0.0408
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0012
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0034 0.0103
Echinococcus granulosus o acyltransferase membrane bound domain 0.0158 0.0476 0.0907
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Brugia malayi dehydrogenases, short chain protein 9 0.0015 0.0009 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus granulosus sterol regulatory element binding protein 0.0056 0.0143 0.0273
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Echinococcus granulosus neuropeptides capa receptor 0.003 0.0058 0.0111
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0006 0.0003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0015 0.0009 0.0009
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0011 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0041 0.0101
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Brugia malayi sulfakinin receptor protein 0.003 0.0058 0.0073
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0124 0.0236
Echinococcus granulosus geminin 0.0519 0.1654 0.315
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.007 0.0132
Entamoeba histolytica hypothetical protein 0.0023 0.0034 0.0235
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Entamoeba histolytica hypothetical protein 0.0158 0.0476 0.3898
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0065 0.0172 0.0616
Echinococcus multilocularis dro:myosuppressin receptor 0.003 0.0058 0.0111
Trypanosoma brucei telomerase reverse transcriptase 0.084 0.2702 1
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0091 0.0552
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Mycobacterium tuberculosis Possible oxidoreductase 0.0015 0.0009 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0091 0.0552
Echinococcus granulosus endoplasmin 0.0029 0.0053 0.01
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Loa Loa (eye worm) runx1 0.0056 0.0141 0.0267
Loa Loa (eye worm) MBOAT family protein 0.0158 0.0476 0.0906
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0006 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0063 0.0371
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.007 0.018
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0015 0.0009 0.0026
Echinococcus multilocularis carbonyl reductase 1 0.0015 0.0009 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0124 0.0236
Brugia malayi neuropeptide F receptor 0.003 0.0058 0.0073
Plasmodium vivax CDK-related protein kinase 6, putative 0.0435 0.138 0.5098
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0063 0.0213
Echinococcus multilocularis solute carrier family 22 0.0014 0.0006 0.0012
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0133 0.0394 0.0751
Echinococcus multilocularis g protein coupled receptor 0.003 0.0058 0.0111
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.006 0.0448
Echinococcus multilocularis g protein coupled receptor 0.003 0.0058 0.0111
Trypanosoma brucei unspecified product 0.0034 0.007 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0143 0.0894
Brugia malayi steroid hormone receptor 0.0034 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0031
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0006 0.0011
Schistosoma mansoni DNA helicase recq1 0.006 0.0154 0.0294
Mycobacterium leprae putative cytochrome p450 0.0025 0.0041 0.0801
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0006 0.0003
Loa Loa (eye worm) melatonin receptor type 1A 0.003 0.0058 0.011
Onchocerca volvulus 0.0483 0.1536 0.1531
Brugia malayi nuclear receptor NHR-88 0.0016 0.0011 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.007 0.0133
Onchocerca volvulus 0.0015 0.0009 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0133 0.0394 0.0751
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Onchocerca volvulus 0.003 0.0058 0.0052
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0041 0.0099
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0018 0.0033
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0015 0.0009 0.0012
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0055 0.0106
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.003 0.0058 0.0111
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0063 0.0213
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.003 0.0058 0.0111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.007 0.0133
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0034 0.0105
Brugia malayi CHE-14 protein 0.0056 0.0143 0.019
Onchocerca volvulus 0.003 0.0058 0.0052
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0111
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0015 0.0009 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Brugia malayi major facilitator superfamily protein 0.0014 0.0006 0.0001
Schistosoma mansoni myosin xvIII 0.003 0.0058 0.0111
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0006 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.003 0.0058 0.011
Leishmania major hypothetical protein, conserved 0.0014 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Brugia malayi Cytochrome P450 family protein 0.0034 0.007 0.0089
Onchocerca volvulus 0.003 0.0058 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0015 0.0009 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Echinococcus multilocularis survival motor neuron protein 1 0.0482 0.1533 0.292
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Plasmodium falciparum flap endonuclease 1 0.0026 0.0043 0.0135
Loa Loa (eye worm) hypothetical protein 0.0165 0.0498 0.0947
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.003 0.0058 0.011
Echinococcus multilocularis transient receptor potential cation channel 0.0015 0.0009 0.0017
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0011 0.0022
Trypanosoma cruzi glycerol uptake protein, putative 0.0158 0.0476 0.1745
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0028 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Schistosoma mansoni lozenge 0.0056 0.0141 0.0268
Schistosoma mansoni protein kinase 0.0031 0.0062 0.0118
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0006 0.0012
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0158 0.0476 0.0907
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.007 0.0088
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.006 0.0114
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0034 0.0103
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Echinococcus granulosus General substrate transporter 0.0088 0.0247 0.047
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0015 0.0007 0.0001
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0076 0.026
Leishmania major mitochondrial DNA polymerase beta 0.0334 0.1048 0.3868
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0158 0.0476 0.0906
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.007 0.0133
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0165 0.0498 0.0947
Echinococcus multilocularis General substrate transporter 0.0088 0.0247 0.047
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0076 0.0458
Schistosoma mansoni hypothetical protein 0.0158 0.0476 0.0907
Brugia malayi hypothetical protein 0.0014 0.0006 0.0001
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0011 0.0008
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0062 0.0206
Onchocerca volvulus 0.003 0.0058 0.0052
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0041 0.0101
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0062 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0011 0.0022
Schistosoma mansoni survival motor neuron protein 0.0098 0.028 0.0534
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.001
Mycobacterium ulcerans ketoacyl reductase 0.0015 0.0009 0.0007
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0031 0.0162
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Leishmania major DNA polymerase kappa, putative 0.0021 0.0027 0.0078
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.003 0.0058 0.0111
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0158 0.0476 0.3898
Brugia malayi tailless protein 0.0016 0.0011 0.0008
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0015 0.0009 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) follicle stimulating hormone receptor 0.003 0.0058 0.011
Leishmania major glycerol uptake protein, putative 0.0158 0.0476 0.1745
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0015 0.0009 0.0009
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0895 0.2884 0.5491
Plasmodium vivax hexose transporter 0.0103 0.0294 0.1068
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Onchocerca volvulus 0.0015 0.0009 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0018 0.0016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0006 0.001
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0011 0.0022
Echinococcus multilocularis heat shock protein 0.0036 0.0076 0.0146
Onchocerca volvulus Sepiapterin reductase homolog 0.0015 0.0009 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0015 0.0009 0.0009
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0053 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.007 0.0088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.007 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.007 0.0088
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.003 0.0058 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.007 0.0088
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0041 0.0099
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.008 0.0222 0.08
Trypanosoma cruzi GUP1, putative 0.0158 0.0476 0.1745
Mycobacterium ulcerans heat shock protein 90 0.0029 0.0053 0.0131
Mycobacterium ulcerans carveol-like dehydrogenase 0.0015 0.0009 0.0007
Schistosoma mansoni intermediate filament proteins 0.003 0.0056 0.0108
Loa Loa (eye worm) heat shock protein 90 0.0036 0.0076 0.0145
Echinococcus granulosus serotonin receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0015 0.0009 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus granulosus WW domain containing oxidoreductase 0.0015 0.0009 0.0017
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0041 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.003 0.0058 0.0111
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Leishmania major hypothetical protein, conserved 0.0028 0.005 0.0165
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Brugia malayi ecdysteroid receptor 0.0034 0.007 0.0088
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0043 0.0238
Echinococcus multilocularis orexin receptor type 2 0.003 0.0058 0.0111
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0015 0.0009 0.0012
Echinococcus granulosus solute carrier family 22 0.0014 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Trypanosoma cruzi GUP1, putative 0.0158 0.0476 0.1745
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0475 0.174
Brugia malayi Serotonin receptor 0.003 0.0058 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Onchocerca volvulus 0.003 0.0058 0.0052
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0043 0.0135
Echinococcus granulosus peptide allatostatin:somatostatin 0.003 0.0058 0.0111
Onchocerca volvulus 0.0015 0.0009 0.0002
Schistosoma mansoni glucose transport protein 0.0103 0.0294 0.056
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0015 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0053 0.0302
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0015 0.0009 0.0009
Echinococcus multilocularis heat shock protein 90 0.0036 0.0076 0.0146
Trypanosoma cruzi hexose transporter 0.0032 0.0063 0.0213
Mycobacterium ulcerans ketoacyl reductase 0.0015 0.0009 0.0007
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0158 0.0476 0.0907
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0062 0.0206
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0015 0.0009 0.0026
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0011 0.0021
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0011 0.0008
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0111
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0015 0.0009 0.0017
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0041 0.0099
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.007 0.0133
Leishmania major cytochrome p450-like protein 0.0025 0.0041 0.0133
Echinococcus multilocularis bloom syndrome protein 0.0086 0.0239 0.0456
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0015 0.0009 0.0012
Entamoeba histolytica hypothetical protein 0.004 0.0089 0.0691
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Echinococcus granulosus solute carrier family 22 0.0014 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0475 0.174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Onchocerca volvulus 0.003 0.0058 0.0052
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0023 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Trichomonas vaginalis DNA helicase recq, putative 0.0065 0.0172 0.1082
Plasmodium vivax heat shock protein 86, putative 0.0036 0.0076 0.026
Leishmania major short chain dehydrogenase, putative 0.0015 0.0009 0.0012
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0158 0.0476 0.1743
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.006 0.0154 0.0549
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0034 0.0618
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0016 0.0015
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0011 0.0021
Echinococcus multilocularis retinol dehydrogenase 11 0.0015 0.0009 0.0017
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.003 0.0058 0.0111
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0146 0.052
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0016 0.003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.005 0.0163
Trichomonas vaginalis endoplasmin, putative 0.0022 0.0031 0.0162
Loa Loa (eye worm) hypothetical protein 0.0482 0.1533 0.2919
Schistosoma mansoni glucose transport protein 0.0103 0.0294 0.056
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi hypothetical protein 0.0018 0.0018 0.0017
Echinococcus granulosus bloom syndrome protein 0.0086 0.0239 0.0456
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Brugia malayi MBOAT family protein 0.0158 0.0476 0.0649
Onchocerca volvulus 0.0015 0.0009 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.003 0.0058 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0016 0.0039
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0064
Brugia malayi hypothetical protein 0.0014 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0211 0.04
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.012 0.0157
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0015 0.0009 0.0012
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0016 0.0039
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0034 0.0078
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0015 0.0009 0.0012
Trichomonas vaginalis steroid dehydrogenase, putative 0.0015 0.0009 0.0016
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0015 0.0009 0.0532
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0015 0.0009 0.0002
Schistosoma mansoni hypothetical protein 0.0103 0.0294 0.056
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.012 0.0228
Brugia malayi Bloom's syndrome protein homolog 0.0086 0.0239 0.0323
Brugia malayi nuclear hormone receptor 0.0034 0.007 0.0088
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0015 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Leishmania major oxidoreductase-like protein 0.0015 0.0009 0.0012
Brugia malayi oxidoreductase 0.0015 0.0009 0.0004
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0041 0.013
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0011 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0011 0.0022
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0034 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Brugia malayi Cytochrome P450 family protein 0.0103 0.0296 0.04
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.003 0.0058 0.0111
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0018 0.0016
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0015 0.0009 0.0009
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0034 0.0065
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.003 0.0058 0.0111
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0151 0.0287
Loa Loa (eye worm) dehydrogenase 0.0015 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0519 0.1654 0.315
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0062 0.0118
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0158 0.0301
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0062 0.0117
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0896 0.5813
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.012 0.0228
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Brugia malayi nuclear receptor RXR 0.0016 0.0011 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0011 0.0022
Loa Loa (eye worm) MBOAT family protein 0.0158 0.0476 0.0906
Brugia malayi isocitrate dehydrogenase 0.0017 0.0016 0.0015
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0119 0.0347 0.0659
Mycobacterium ulcerans oxidoreductase 0.0015 0.0009 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Leishmania major glycerol uptake protein, putative 0.0158 0.0476 0.1745
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Echinococcus multilocularis lamin dm0 0.003 0.0056 0.0108
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0034 0.0105
Echinococcus granulosus Niemann Pick C1 protein 0.0077 0.0211 0.0401
Schistosoma mansoni thyroid hormone receptor 0.0034 0.007 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0294 0.1881
Echinococcus granulosus 7tm_1 domain containing protein 0.003 0.0058 0.0111
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0091 0.0316
Toxoplasma gondii Hsp90 domain-containing protein 0.0015 0.0007 0.0004
Mycobacterium ulcerans oxidoreductase 0.0015 0.0009 0.0007
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0041 0.0099
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0158 0.0476 0.0907
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.007 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.007 0.0132
Brugia malayi hypothetical protein 0.0016 0.0011 0.0008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0016 0.003
Brugia malayi intermediate filament protein 0.003 0.0056 0.007
Brugia malayi RE15519p 0.003 0.0058 0.0073
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Leishmania major hypothetical protein, conserved 0.0158 0.0476 0.1745
Schistosoma mansoni opsin-like receptor 0.003 0.0058 0.0111
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0011 0.0021
Echinococcus granulosus carbonyl reductase 1 0.0015 0.0009 0.0017
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0015 0.0009 0.0012
Schistosoma mansoni protein kinase 0.0031 0.0062 0.0118
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni neuropeptide f receptor 76f 0.003 0.0058 0.0111
Brugia malayi hypothetical protein 0.0015 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.003 0.0058 0.0111
Loa Loa (eye worm) MBOAT family protein 0.0158 0.0476 0.0906
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Echinococcus multilocularis solute carrier family 22 0.0014 0.0006 0.0012
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0062 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Schistosoma mansoni DNA helicase recq5 0.006 0.0154 0.0294
Echinococcus granulosus muscleblind protein 0.0165 0.0498 0.0948
Leishmania major heat shock protein, putative 0.0015 0.0007 0.0006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.003 0.0058 0.0111
Plasmodium falciparum heat shock protein 90 0.0036 0.0076 0.026
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Mycobacterium ulcerans short-chain dehydrogenase 0.0015 0.0009 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0041 0.0101
Mycobacterium ulcerans dehydrogenase 0.0015 0.0009 0.0007
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0077 0.0211 0.0401
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0062 0.0206
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0195 0.0595 0.0589
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0417 0.1158
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0041 0.0099
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0043 0.0137
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0009
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0077 0.0211 0.1697
Leishmania major glycerol uptake protein, putative 0.0158 0.0476 0.1745
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0011 0.0022
Loa Loa (eye worm) heat shock protein 75 0.0015 0.0007 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0306 0.0414
Brugia malayi N-terminal motif family protein 0.0195 0.0595 0.0813
Brugia malayi MBOAT family protein 0.0158 0.0476 0.0649
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0896 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.1428 0.4623 0.8803
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.007 0.0133
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0062 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.007 0.0088
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0015 0.0009 0.0017
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Onchocerca volvulus 0.0443 0.1405 0.14
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0018 0.0033
Echinococcus multilocularis GPCR, family 2 0.0049 0.012 0.0228
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0006 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0011 0.0022
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0111
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0158 0.0301
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0158 0.0476 0.0907
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0294 0.056
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0021
Schistosoma mansoni amine GPCR 0.003 0.0058 0.0111
Brugia malayi nuclear receptor NHR-67 0.0016 0.0011 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.007 0.0133
Echinococcus granulosus tachykinin peptides receptor 99D 0.003 0.0058 0.0111
Echinococcus multilocularis neuropeptide receptor 0.003 0.0058 0.0111
Echinococcus multilocularis dna polymerase eta 0.0014 0.0006 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0041 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.007 0.0088
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0158 0.0476 0.0907
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0016 0.0031
Onchocerca volvulus 0.003 0.0058 0.0052
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0015 0.0009 0.0004
Echinococcus multilocularis retinol dehydrogenase 11 0.0015 0.0009 0.0017
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0011 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.007 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.003 0.0058 0.011
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0029 0.0053 0.1074
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.003 0.0058 0.0111
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.003 0.0058 0.0111
Onchocerca volvulus 0.003 0.0056 0.005
Trypanosoma cruzi heat shock protein 85, putative 0.0029 0.0053 0.0174
Echinococcus granulosus sterol O acyltransferase 1 0.1621 0.5252 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0158 0.0476 0.3898
Echinococcus granulosus fmrfamide receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0417 0.116
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.003 0.0058 0.0111
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0294 0.056
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0063 0.0213
Echinococcus multilocularis alpha 1A adrenergic receptor 0.003 0.0058 0.0111
Echinococcus multilocularis steroid dehydrogenase 0.0015 0.0009 0.0017
Brugia malayi diacylglycerol acyltransferase 0.0158 0.0476 0.0649
Trypanosoma brucei Heat shock protein 83, putative 0.0036 0.0076 0.0263
Trypanosoma brucei glucose transporter 2A 0.0032 0.0063 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0062 0.0362
Plasmodium falciparum protein kinase 7 0.029 0.0905 0.3335
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0018 0.0033
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0119 0.0348 0.0473
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Schistosoma mansoni opsin-like receptor 0.003 0.0058 0.0111
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0059 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0063 0.0371
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Trypanosoma brucei glucose transporter 1E 0.0032 0.0063 0.0213
Echinococcus granulosus lamin 0.003 0.0056 0.0108
Brugia malayi Dopamine receptor 0.003 0.0058 0.0073
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0076 0.0262
Brugia malayi putative neuropeptide receptor NPR1 0.003 0.0058 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0063 0.0371
Leishmania major glucose transporter, lmgt1 0.0032 0.0063 0.0213
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0043 0.0135
Echinococcus granulosus g protein coupled receptor 0.003 0.0058 0.0111
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0089 0.0169
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Echinococcus multilocularis carbonyl reductase 1 0.0015 0.0009 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.003 0.0058 0.0111
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0063 0.0213
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0043 0.0307
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.007 0.0133
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.007 0.0132
Brugia malayi follicle stimulating hormone receptor 0.003 0.0058 0.0073
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0158 0.0476 0.1743
Schistosoma mansoni endoplasmin 0.0036 0.0076 0.0146
Brugia malayi hypothetical protein 0.0014 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0015 0.0009 0.0012
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0039
Mycobacterium ulcerans ketoacyl reductase 0.0015 0.0009 0.0007
Schistosoma mansoni biogenic amine (dopamine) receptor 0.003 0.0058 0.0111
Brugia malayi Serotonin receptor 0.003 0.0058 0.0073
Schistosoma mansoni hypothetical protein 0.0098 0.028 0.0534
Echinococcus multilocularis carbonyl reductase 1 0.0015 0.0009 0.0017
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.003 0.0058 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.003 0.0058 0.0111
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.084 0.2702 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0053 0.0302
Echinococcus granulosus somatostatin receptor 0.003 0.0058 0.0111
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0076 0.0262
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0043 0.0081
Plasmodium falciparum hexose transporter 0.0103 0.0294 0.1068
Onchocerca volvulus 0.0061 0.0158 0.0152
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.006 0.0349
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0063 0.0213
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Echinococcus multilocularis serotonin receptor 0.003 0.0058 0.0111
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0041 0.0099
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0041 0.0099
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Schistosoma mansoni nuclear receptor 0.0016 0.0011 0.0022
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.006 0.0075
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0062 0.0206
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0043 0.008
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0015 0.0007 0.0014
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0006 0.0003
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0041 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.003 0.0058 0.0111
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0015 0.0009 0.0012
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0417 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.003 0.0058 0.0111
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.006 0.0198
Schistosoma mansoni sugar transporter 0.0014 0.0006 0.0012
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0041 0.0099
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.003 0.0058 0.0111
Echinococcus multilocularis G-protein coupled receptor, putative 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Plasmodium vivax steroid dehydrogenase, putative 0.0015 0.0009 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.005 0.0163
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0041 0.0101
Giardia lamblia DINP protein human, muc B family 0.0021 0.0027 0.0076
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Trypanosoma brucei heat shock protein 90, putative 0.0036 0.0076 0.0263
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0015 0.0009 0.0012
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0011 0.0022
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0023 0.0048
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.003 0.0058 0.0111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0124 0.0236
Schistosoma mansoni hypothetical protein 0.004 0.0089 0.0169
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0016
Echinococcus multilocularis Protein lozenge 0.0056 0.0141 0.0268
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0034 0.0065
Echinococcus granulosus FTZ F1 alpha 0.0034 0.007 0.0133
Onchocerca volvulus 0.0098 0.028 0.0274
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0124 0.0236
Trypanosoma brucei glucose transporter, putative 0.0032 0.0063 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.007 0.0088
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Mycobacterium tuberculosis Probable dehydrogenase 0.0015 0.0009 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.039 0.0741
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.005 0.0165
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0117
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.0467 0.0888
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0015 0.0009 0.0009
Loa Loa (eye worm) hhat protein 0.0158 0.0476 0.0906
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0011 0.0005
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0006 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0158 0.0476 0.0906
Onchocerca volvulus 0.0034 0.007 0.0063
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0029 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0009
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0015 0.0009 0.0009
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.003 0.0058 0.0111
Onchocerca volvulus 0.003 0.0058 0.0052
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0076 0.0262
Brugia malayi Tachykinin-like peptides receptor 99D 0.003 0.0058 0.0073
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 0.1048 0.3868
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0158 0.0476 0.0907
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0132
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0475 0.174
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.006 0.0154 0.0294
Trichomonas vaginalis transmembrane protein nessy, putative 0.0158 0.0476 0.3071
Onchocerca volvulus 0.003 0.0058 0.0052
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0015 0.0009 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0034 0.007 0.0133
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0034 0.0105
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Schistosoma mansoni heat shock protein 0.0036 0.0076 0.0146
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.005 0.0165
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0015 0.0009 0.0016
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0015 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Schistosoma mansoni amine GPCR 0.003 0.0058 0.0111
Onchocerca volvulus 0.0015 0.0009 0.0002
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0041 0.0099
Brugia malayi Cytochrome P450 family protein 0.0025 0.0041 0.0049
Trypanosoma cruzi short chain dehydrogenase, putative 0.0015 0.0009 0.0012
Brugia malayi Pre-SET motif family protein 0.0061 0.0158 0.021
Brugia malayi Telomerase reverse transcriptase 0.2235 0.7257 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0041 0.0101
Echinococcus granulosus lamin dm0 0.003 0.0056 0.0108
Brugia malayi Flap endonuclease-1 0.0026 0.0043 0.0051
Schistosoma mansoni histamine h1 receptor 0.003 0.0058 0.0111
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0015 0.0009 0.0016
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.006 0.0154 0.0294
Echinococcus granulosus solute carrier family 22 0.0014 0.0006 0.0012
Entamoeba histolytica short chain dehydrogenase family protein 0.0015 0.0009 0.0026
Loa Loa (eye worm) sugar transporter 0.0014 0.0006 0.0011
Echinococcus granulosus solute carrier family 22 0.0014 0.0006 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.0158 0.0476 0.0906
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0111
Echinococcus multilocularis sterol regulatory element binding protein 0.0056 0.0143 0.0273
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0015 0.0009 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Echinococcus granulosus neuropeptides capa receptor 0.003 0.0058 0.0111
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0158 0.0476 0.0907
Leishmania major dehydrogenase-like protein 0.0015 0.0009 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Brugia malayi Cam kinase protein 1 0.0031 0.0062 0.0077
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0059 0.0112
Echinococcus granulosus intermediate filament protein 0.003 0.0056 0.0108
Brugia malayi hypothetical protein 0.0482 0.1533 0.2107
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0015 0.0009 0.0012
Schistosoma mansoni steroid dehydrogenase 0.0015 0.0009 0.0017
Mycobacterium ulcerans short chain dehydrogenase 0.0015 0.0009 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0041 0.0101
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0006 0.0011
Plasmodium vivax SET domain protein, putative 0.0061 0.0158 0.0563
Echinococcus multilocularis sex peptide receptor 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0041 0.0101
Echinococcus multilocularis neuropeptides capa receptor 0.003 0.0058 0.0111
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.007 0.0088
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0009
Brugia malayi Serotonin/octopamine receptor family protein 7 0.003 0.0058 0.0073
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0041 0.0079
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0076 0.0263
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0015 0.0009 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0091 0.0316
Brugia malayi Muscleblind-like protein 0.0165 0.0498 0.0679
Echinococcus multilocularis fmrfamide receptor 0.003 0.0058 0.0111
Brugia malayi Endoplasmin precursor 0.0036 0.0076 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0124 0.0236
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0059 0.0197
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0027 0.006
Brugia malayi Latrophilin receptor protein 2 0.0049 0.012 0.0157
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.003 0.0058 0.011
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0011 0.0022
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0015 0.0009 0.0017
Echinococcus multilocularis endoplasmin 0.0029 0.0053 0.01
Schistosoma mansoni blooms syndrome DNA helicase 0.0055 0.014 0.0267
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.1048 0.3868
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0158 0.0476 0.1743
Echinococcus multilocularis muscleblind protein 0.0165 0.0498 0.0948
Echinococcus granulosus neuropeptide FF receptor 2 0.003 0.0058 0.0111
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0176 0.0533 0.1486
Brugia malayi MBOAT family protein 0.0158 0.0476 0.0649
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.039 0.0741
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0027 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0158 0.0301
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.007 0.0133
Entamoeba histolytica recQ family helicase, putative 0.0065 0.0172 0.1377
Loa Loa (eye worm) hhat protein 0.0158 0.0476 0.0906
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0476 0.3071
Echinococcus granulosus rhodopsin orphan GPCR 0.003 0.0058 0.0111
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0051 0.0126 0.0445
Brugia malayi hypothetical protein 0.0018 0.0018 0.0016
Entamoeba histolytica recQ family DNA helicase 0.003 0.0059 0.0439
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0158 0.0476 0.0907
Onchocerca volvulus Neuropeptide F receptor homolog 0.003 0.0058 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0033
Leishmania major glucose transporter, lmgt3 0.0032 0.0063 0.0213
Plasmodium falciparum telomerase reverse transcriptase 0.084 0.2702 1
Loa Loa (eye worm) hypothetical protein 0.0443 0.1405 0.2675
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.003 0.0058 0.0111
Onchocerca volvulus 0.003 0.0058 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0041 0.0101
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Echinococcus granulosus hypothetical protein 0.0015 0.0009 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0158 0.0301
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0004
Leishmania major heat shock protein 83-1 0.0036 0.0076 0.0263
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0154 0.0549
Schistosoma mansoni lamin 0.003 0.0056 0.0108
Echinococcus multilocularis Niemann Pick C1 protein 0.0133 0.0394 0.0751
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0027 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.003 0.0058 0.0111
Echinococcus granulosus neuropeptide receptor A26 0.1428 0.4623 0.8803
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.011
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0015 0.0009 0.0012
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0006 0.0001
Trypanosoma brucei sugar transporter, putative 0.0014 0.0006 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0063 0.0371
Plasmodium falciparum mitogen-activated protein kinase 2 0.0166 0.05 0.1833
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0009 0.0012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0112 0.0396
Toxoplasma gondii heat shock protein 90, putative 0.0036 0.0076 0.026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0007
Leishmania major glycerol uptake protein, putative 0.0158 0.0476 0.1745
Schistosoma mansoni amine GPCR 0.003 0.0058 0.0111
Schistosoma mansoni neuropeptide receptor 0.003 0.0058 0.0111
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.007 0.0132
Schistosoma mansoni neuropeptide receptor 0.003 0.0058 0.0111
Echinococcus granulosus survival motor neuron protein 1 0.0482 0.1533 0.292
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.007 0.0088
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.003 0.0058 0.0073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0062 0.0118
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0041 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0119 0.0347 0.0659
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0041 0.0099
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0015 0.0009 0.0009
Echinococcus multilocularis steroid dehydrogenase 0.0015 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0143 0.0272
Echinococcus granulosus retinol dehydrogenase 11 0.0015 0.0009 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0025
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0062 0.0206
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0091 0.0316
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0041 0.0101
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0103
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.006 0.0154 0.0205
Brugia malayi Sugar transporter family protein 0.0103 0.0294 0.0398
Trypanosoma brucei heat shock protein, putative 0.0036 0.0076 0.0263
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Brugia malayi hypothetical protein 0.003 0.0058 0.0073
Loa Loa (eye worm) hypothetical protein 0.0155 0.0467 0.0888
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0009
Schistosoma mansoni short chain dehydrogenase 0.0015 0.0009 0.0017
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0112 0.0396
Echinococcus granulosus oxidoreductase 0.0015 0.0009 0.0017
Leishmania major quinonoid dihydropteridine reductase 0.0015 0.0009 0.0012
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0034 0.0065
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0063 0.0213
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0158 0.0476 0.0907
Echinococcus multilocularis conserved hypothetical protein 0.0015 0.0009 0.0017
Schistosoma mansoni carbonyl reductase 0.0015 0.0009 0.0017
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.003 0.0058 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0041 0.0101
Leishmania major glucose transporter, lmgt2 0.0032 0.0063 0.0213
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.006 0.0154 0.0205
Schistosoma mansoni protein kinase 0.0031 0.0062 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0016
Plasmodium falciparum protein kinase 6 0.0435 0.138 0.5098
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0111

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 52 % Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay at 1uM ChEMBL. 16942874
Inhibition (functional) = 52 % Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay at 1uM ChEMBL. 16942874

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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