Detailed information for compound 513002

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1093.31 | Formula: C52H88N10O15
  • H donors: 16 H acceptors: 15 LogP: 0.34 Rotable bonds: 24
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCN[C@@H]1NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC(=O)[C@H](C[C@@H]1O)NC(=O)CCCCCCCC[C@H](C[C@H](CC)C)C)[C@H](O)C)C[C@@H](C2)O)[C@H]([C@H](c1ccc(cc1)O)O)O)[C@H](CCN)O
  • InChi: 1S/C52H88N10O15/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75)/t28-,29-,30+,33+,34-,35-,36+,37-,38+,40-,41-,42-,43-,44-,45-,46+/m0/s1
  • InChiKey: JYIKNQVWKBUSNH-FLHBIXOJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0072 0.1055
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0038 0.0153
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0239 0.0585 0.2411
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0005 0.0005
Leishmania major cytochrome p450-like protein 0.0054 0.0086 0.1113
Echinococcus granulosus retinoic acid receptor rxr beta a 0.024 0.0588 0.0588
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0132 0.0298 0.1003
Brugia malayi beta-lactamase family protein 0.0036 0.0038 0.0129
Onchocerca volvulus 0.0099 0.0207 0.0607
Leishmania major DNA polymerase kappa, putative 0.0171 0.0401 0.518
Echinococcus granulosus lysosomal alpha glucosidase 0.0184 0.0437 0.0437
Echinococcus granulosus multidrug resistance protein 1 0.0057 0.0094 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0038 0.0068
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0093 0.0093
Onchocerca volvulus 0.1282 0.3388 1
Brugia malayi steroid hormone receptor 0.0132 0.0298 0.1003
Trypanosoma brucei metacaspase MCA2 0.0048 0.0072 0.0935
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0019 0.0019
Echinococcus multilocularis neuroglian 0.0038 0.0045 0.0045
Brugia malayi ecdysteroid receptor 0.0132 0.0298 0.1003
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0014 0.0052
Schistosoma mansoni phd/f-box containing protein 0.0074 0.0142 0.0142
Plasmodium vivax metacaspase 1, putative 0.0048 0.0072 0.1055
Echinococcus granulosus cpg binding protein 0.0131 0.0293 0.0293
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0052 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0045 0.0152
Entamoeba histolytica P-glycoprotein-5 0.0057 0.0094 0.0185
Giardia lamblia PHD finger protein 15 0.003 0.0022 0.0035
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi tailless protein 0.0062 0.011 0.037
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0001 0.0015
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0024 0.0007 0.0007
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.004 0.007
Echinococcus granulosus muscleblind protein 0.0153 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0089
Toxoplasma gondii endonuclease IV APN 0.0084 0.0168 0.0633
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0017 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0073 0.0137 0.0137
Mycobacterium ulcerans hypothetical protein 0.0049 0.0073 0.0295
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0351
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0152 0.0152
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0057 0.0094 0.0094
Plasmodium falciparum metacaspase 1 0.0048 0.0072 0.1013
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Echinococcus multilocularis ecdysone induced protein 78C 0.0132 0.0298 0.0298
Onchocerca volvulus 0.0033 0.003 0.0083
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0132 0.0298 0.0298
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0025 0.001 0.001
Echinococcus granulosus dnaJ subfamily C 6 0.0069 0.0128 0.0128
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0038 0.0153
Loa Loa (eye worm) DR-78 0.0062 0.011 0.037
Echinococcus multilocularis lysosomal alpha glucosidase 0.0184 0.0437 0.0437
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.0471 0.1941
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0174 0.0411 0.5309
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0132 0.0298 0.0298
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.007 0.013 0.013
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.0114 0.1475
Schistosoma mansoni RAR-like nuclear receptor 0.0132 0.0298 0.0298
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0056 0.0093 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.034 0.0857 0.0857
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0108 0.0233 0.3007
Schistosoma mansoni DNA polymerase eta 0.0211 0.0509 0.0509
Leishmania major cytochrome p450-like protein 0.0035 0.0036 0.0468
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0038 0.0038
Trichomonas vaginalis DNA polymerase eta, putative 0.0212 0.0513 0.1014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0024
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0007 0.0005
Giardia lamblia Fructose-bisphosphate aldolase 0.1889 0.5018 1
Schistosoma mansoni hypothetical protein 0.0165 0.0384 0.0384
Echinococcus granulosus synaptic vesicular amine transporter 0.0207 0.0497 0.0497
Trypanosoma cruzi hexose transporter, putative 0.0033 0.003 0.0382
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0097 0.0097
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0132 0.0298 0.0298
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1889 0.5018 1
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.0438
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0114 0.1475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0132 0.0298 0.1003
Mycobacterium ulcerans leucyl aminopeptidase 0.0108 0.0233 0.0955
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0353 0.0353
Schistosoma mansoni alpha-glucosidase 0.0159 0.0368 0.0368
Schistosoma mansoni transient receptor potential channel 4 0.0115 0.0251 0.0251
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Onchocerca volvulus 0.0033 0.003 0.0083
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0057 0.0094 0.0317
Schistosoma mansoni DNA helicase recq1 0.0043 0.0058 0.0058
Brugia malayi DnaJ domain containing protein 0.0069 0.0128 0.0431
Loa Loa (eye worm) histone methyltransferase 0.0046 0.0067 0.0224
Loa Loa (eye worm) hypothetical protein 0.0107 0.0229 0.0772
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0157 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Schistosoma mansoni nuclear hormone receptor 0.0062 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0083 0.028
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0039 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Loa Loa (eye worm) transcription factor SMAD2 0.0509 0.1311 0.4413
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0017 0.0215
Plasmodium falciparum M17 leucyl aminopeptidase 0.0108 0.0233 0.3408
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0011 0.0038
Mycobacterium tuberculosis Probable oxidoreductase 0.0266 0.0657 0.2707
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0107 0.036
Schistosoma mansoni rotamase 0.0067 0.0123 0.0123
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0025 0.0011 0.0136
Schistosoma mansoni sugar transporter 0.0033 0.003 0.003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0174 0.0411 0.5309
Schistosoma mansoni glutaminase 0.0589 0.1525 0.1525
Loa Loa (eye worm) multidrug resistance protein 3 0.0057 0.0094 0.0317
Mycobacterium ulcerans oxidoreductase 0.0025 0.0011 0.0038
Brugia malayi hypothetical protein 0.0166 0.0387 0.1302
Plasmodium falciparum JmjC domain-containing protein, putative 0.0074 0.0142 0.2056
Loa Loa (eye worm) hypothetical protein 0.0048 0.0071 0.0238
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0052 0.0094
Brugia malayi cytochrome P450 0.0035 0.0036 0.0122
Echinococcus granulosus caspase 3 0.008 0.0156 0.0156
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.003 0.0099
Echinococcus granulosus lamin 0.0088 0.0178 0.0178
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0093 0.1202
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Loa Loa (eye worm) hypothetical protein 0.008 0.0157 0.053
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0203 0.2631
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0048 0.0193
Brugia malayi nuclear receptor RXR 0.007 0.013 0.0438
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0007 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0075 0.0075
Schistosoma mansoni transient receptor potential channel 0.0115 0.0251 0.0251
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0045 0.0152
Brugia malayi nuclear receptor NHR-67 0.0062 0.011 0.037
Brugia malayi Transient-receptor-potential like protein 0.0046 0.0066 0.0222
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0063 0.0116
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0014 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0166 0.0388 0.0388
Onchocerca volvulus 0.0063 0.011 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0478
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0307 0.0307
Toxoplasma gondii facilitative glucose transporter GT1 0.0033 0.003 0.0108
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0035 0.0119
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0075 0.0075
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0036 0.0144
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.004 0.0514
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0132 0.0298 0.0876
Onchocerca volvulus 0.0039 0.0048 0.0138
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0085 0.0085
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) doublecortin family protein 0.0063 0.011 0.0371
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0028 0.0017 0.0017
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0168 0.2439
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0073 0.0942
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Onchocerca volvulus 0.0029 0.002 0.0054
Schistosoma mansoni vesicular amine transporter 0.0207 0.0497 0.0497
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0014 0.0052
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0074 0.0142 0.1837
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0157 0.0364 0.0364
Brugia malayi nuclear hormone receptor family member odr-7 0.0062 0.011 0.037
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0007 0.0084
Brugia malayi Cytochrome P450 family protein 0.0035 0.0036 0.0122
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0099 0.0207 0.0697
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0192 0.0458 0.1542
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.001 0.001
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0043 0.0058 0.0058
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.013 0.0438
Loa Loa (eye worm) hypothetical protein 0.008 0.0157 0.053
Schistosoma mansoni nuclear hormone receptor 0.0132 0.0298 0.0298
Echinococcus multilocularis microtubule associated protein 2 0.3743 1 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0093 0.1202
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.004 0.0514
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0007 0.0024
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0093 0.0313
Trypanosoma cruzi metacaspase 5, putative 0.0048 0.0072 0.0935
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0086 0.0172 0.0579
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0048 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0132 0.0298 0.0876
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0047 0.007 0.007
Onchocerca volvulus 0.0033 0.003 0.0083
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0093 0.1202
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.011 0.011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Echinococcus multilocularis JmjC domain containing protein 4 0.0074 0.0142 0.0142
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1714 0.4549 0.4549
Brugia malayi hypothetical protein 0.0062 0.011 0.037
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0203 0.0203
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Trichomonas vaginalis sugar transport protein, putative 0.0033 0.003 0.005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0166 0.0388 0.0388
Schistosoma mansoni lipoxygenase 0.0193 0.046 0.046
Leishmania major hypothetical protein, conserved 0.0036 0.0038 0.0497
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0132 0.0298 0.1003
Echinococcus multilocularis solute carrier family 22 0.0033 0.003 0.003
Schistosoma mansoni protein tyrosine phosphatase 0.0028 0.0017 0.0017
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0057 0.0094 0.1218
Plasmodium falciparum phosphoglycerate kinase 0.0174 0.0411 0.6069
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0074 0.0962
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0078 0.0152 0.0512
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.004 0.0158
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.011 0.011
Trypanosoma brucei unspecified product 0.0108 0.0233 0.3009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Trypanosoma cruzi DNA polymerase eta, putative 0.0211 0.0509 0.6576
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0151 0.0151
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0108 0.0233 0.3007
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0017 0.0063
Plasmodium falciparum SET domain protein, putative 0.0073 0.0137 0.1985
Brugia malayi Phospholipase A2 family protein 0.0075 0.0143 0.0481
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0011 0.0013
Brugia malayi M-phase phosphoprotein, mpp8 0.0123 0.0272 0.0914
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0017 0.0059
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0019 0.0243
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0052 0.0175
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.003 0.0382
Echinococcus granulosus jumonji domain containing 1A 0.0074 0.0142 0.0142
Brugia malayi hypothetical protein 0.0062 0.011 0.037
Schistosoma mansoni hypothetical protein 0.0337 0.0848 0.0848
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0022 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0075 0.0075
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0136 0.0307 0.0603
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0042 0.0042
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0067 0.0121 0.1742
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.0086 0.1113
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0132 0.0298 0.1003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1127 0.2971 1
Echinococcus granulosus cysteine protease atg4b 0.0048 0.0071 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0036 0.0468
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0024 0.0007 0.0007
Brugia malayi Pre-SET motif family protein 0.0166 0.0388 0.1305
Trypanosoma brucei chrX additional, unordered contigs 0.0049 0.0073 0.0942
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0222 0.2876
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0128 0.0286 0.0286
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0042 0.0042
Toxoplasma gondii peptidylprolyl isomerase 0.0066 0.0119 0.0449
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0099 0.0207 0.0207
Echinococcus multilocularis roundabout 2 0.0038 0.0045 0.0045
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0132 0.0298 0.0298
Onchocerca volvulus Bile acid receptor homolog 0.0132 0.0298 0.0876
Plasmodium falciparum importin beta, putative 0.0032 0.0027 0.0335
Schistosoma mansoni phosphatidylserine receptor 0.0074 0.0142 0.0142
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0073 0.0137 0.0137
Trichomonas vaginalis protein kinase inhibitor, putative 0.0069 0.0128 0.0247
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0036 0.0144
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Echinococcus granulosus geminin 0.0904 0.2373 0.2373
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.004 0.044
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0053 0.0053
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.006 0.0104 0.0104
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.003 0.0382
Leishmania major pteridine reductase 1 0.0036 0.0039 0.0509
Brugia malayi nuclear hormone receptor 0.0062 0.011 0.037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0011 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0018 0.0027
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0033 0.003 0.0373
Brugia malayi ABC transporter family protein 0.0057 0.0094 0.0317
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0001 0.0005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0005 0.0059
Toxoplasma gondii thioredoxin reductase 0.0105 0.0224 0.0847
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.011 0.0321
Trichomonas vaginalis ABC transporter, putative 0.0057 0.0094 0.0179
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0174 0.0411 0.081
Echinococcus multilocularis voltage gated potassium channel 0.0025 0.001 0.001
Echinococcus granulosus contactin 0.0038 0.0045 0.0045
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0155 0.0359 0.0359
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0014 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0072 0.0135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0239 0.0585 0.2411
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.0114 0.1475
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0082 0.0155
Echinococcus granulosus mixed lineage leukemia protein mll 0.0039 0.0046 0.0046
Brugia malayi jmjC domain containing protein 0.0074 0.0142 0.0478
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) hypothetical protein 0.0153 0.0353 0.1189
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0066 0.0222
Schistosoma mansoni steroid hormone receptor ad4bp 0.0132 0.0298 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Plasmodium falciparum glutathione reductase 0.0105 0.0224 0.3278
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0057 0.0094 0.0179
Brugia malayi photoreceptor-specific nuclear receptor 0.0132 0.0298 0.1003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0058 0.0216
Echinococcus multilocularis survival motor neuron protein 1 0.0524 0.1351 0.1351
Echinococcus granulosus lamin dm0 0.0088 0.0178 0.0178
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0014 0.0026
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0025 0.0011 0.0038
Trichomonas vaginalis rotamase, putative 0.0066 0.0119 0.0229
Echinococcus granulosus multidrug resistance protein 1 0.0039 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.004 0.0134
Onchocerca volvulus 0.0033 0.003 0.0083
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0045 0.0063 0.0213
Leishmania major GTP-binding protein, putative 0.0023 0.0005 0.0059
Trypanosoma brucei glucose transporter 2A 0.0033 0.003 0.0382
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0038 0.0045 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Schistosoma mansoni chromobox protein 0.0084 0.0167 0.0167
Echinococcus granulosus FTZ F1 alpha 0.0132 0.0298 0.0298
Brugia malayi MH2 domain containing protein 0.0035 0.0035 0.0119
Echinococcus multilocularis bloom syndrome protein 0.0073 0.0138 0.0138
Trypanosoma brucei DNA polymerase kappa, putative 0.0122 0.027 0.3489
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi Protein set-1 0.0073 0.0137 0.0462
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0025 0.0011 0.0137
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0007 0.0007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.004 0.004
Trypanosoma cruzi hexose transporter, putative 0.0033 0.003 0.0382
Schistosoma mansoni flap endonuclease-1 0.0026 0.0011 0.0011
Echinococcus granulosus Smad4 0.0035 0.0035 0.0035
Trichomonas vaginalis ABC transporter, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0157 0.0364 0.1223
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0132 0.0298 0.1003
Echinococcus multilocularis caspase 0.0128 0.0286 0.0286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Onchocerca volvulus 0.0107 0.0228 0.067
Echinococcus multilocularis lysine specific demethylase 6a 0.0074 0.0142 0.0142
Echinococcus granulosus Chromobox protein 3 0.0024 0.0007 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Trypanosoma cruzi sugar transporter, putative 0.0033 0.003 0.0382
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0089
Loa Loa (eye worm) hypothetical protein 0.0137 0.0312 0.1049
Echinococcus multilocularis jumonji domain containing 1A 0.0074 0.0142 0.0142
Echinococcus granulosus nuclear receptor nhr 48 0.0062 0.011 0.011
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0062 0.011 0.011
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0097 0.0097
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0052 0.0101
Onchocerca volvulus Phospholipase A2 homolog 0.0075 0.0143 0.0418
Echinococcus multilocularis multidrug resistance protein 1 0.0039 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0052 0.0094
Toxoplasma gondii ABC1 family protein 0.0036 0.0038 0.0142
Schistosoma mansoni sugar transporter 0.0033 0.003 0.003
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0042 0.0042
Schistosoma mansoni vesicular amine transporter 0.007 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0063 0.011 0.0371
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0198 0.0474 0.0474
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0007 0.0023
Brugia malayi CHD4 protein 0.0031 0.0026 0.0088
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0038 0.0153
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0035 0.0035
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Brugia malayi Smad1 0.0035 0.0035 0.0119
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0174 0.0411 0.6034
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0207 0.0207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0045 0.0152
Echinococcus multilocularis neuropeptide s receptor 0.1036 0.2726 0.2726
Echinococcus granulosus survival motor neuron protein 1 0.0524 0.1351 0.1351
Echinococcus multilocularis lysine specific demethylase 5A 0.0279 0.0692 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Brugia malayi beta-lactamase family protein 0.0036 0.0038 0.0129
Plasmodium vivax hypothetical protein, conserved 0.003 0.0022 0.0305
Schistosoma mansoni chromobox protein 0.0024 0.0007 0.0007
Mycobacterium tuberculosis Conserved protein 0.0036 0.0038 0.0153
Echinococcus granulosus phd:f box containing protein 0.0074 0.0142 0.0142
Schistosoma mansoni cell adhesion molecule 0.0038 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0173
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.011 0.011
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0017 0.0031
Echinococcus multilocularis multidrug resistance protein 1 0.0057 0.0094 0.0094
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0047 0.0068 0.023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0014 0.0052
Brugia malayi CXXC zinc finger family protein 0.0124 0.0274 0.0923
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0011 0.0137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.004 0.0514
Onchocerca volvulus 0.0027 0.0014 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0007 0.0005
Onchocerca volvulus 0.0033 0.003 0.0083
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0033 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0132 0.0298 0.1003
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus multilocularis dnaJ subfamily C 6 0.0069 0.0128 0.0128
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0152 0.0152
Trypanosoma brucei glucose transporter 1E 0.0033 0.003 0.0382
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Echinococcus multilocularis smad 0.0035 0.0035 0.0035
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0239 0.0585 0.2411
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0132 0.0298 0.0298
Schistosoma mansoni ran 0.0023 0.0005 0.0005
Plasmodium vivax DNA repair protein REV1, putative 0.0049 0.0073 0.1063
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0017 0.0091
Giardia lamblia Kinase, PLK 0.0097 0.0203 0.0397
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0057 0.0094 0.0094
Schistosoma mansoni cpg binding protein 0.0124 0.0274 0.0274
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0014 0.0026
Echinococcus granulosus chromobox protein 2 0.0024 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0132 0.0298 0.1003
Echinococcus multilocularis chromobox protein 1 0.0084 0.0167 0.0167
Echinococcus granulosus Sugar transporter ERD6 protein 0.0033 0.003 0.003
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0036 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0027 0.0349
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0014 0.0183
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0036 0.0468
Loa Loa (eye worm) hypothetical protein 0.0166 0.0388 0.1305
Trypanosoma brucei glucosidase, putative 0.0041 0.0052 0.0672
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.004 0.044
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0027 0.0349
Entamoeba histolytica P-glycoprotein-2 0.0057 0.0094 0.0185
Onchocerca volvulus Alhambra homolog 0.003 0.0022 0.006
Brugia malayi nuclear receptor RXR 0.0062 0.011 0.037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.023 0.0773
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0039 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Brugia malayi PAS domain containing protein 0.0053 0.0085 0.0287
Echinococcus multilocularis nuclear receptor nhr 48 0.0062 0.011 0.011
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0036 0.0144
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0093 0.0176
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.0773 1
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0038 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.0509 0.1311 0.4413
Echinococcus granulosus smad 0.0035 0.0035 0.0035
Leishmania major glucose transporter, lmgt3 0.0033 0.003 0.0382
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0057 0.0094 0.0179
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0284 0.0704 0.0704
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Giardia lamblia DINP protein human, muc B family 0.0171 0.0401 0.079
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0007 0.0012
Mycobacterium ulcerans integral membrane transport protein 0.0033 0.003 0.0116
Echinococcus multilocularis L aminoadipate semialdehyde 0.0099 0.0207 0.0207
Echinococcus multilocularis chromobox protein 2 0.0024 0.0007 0.0007
Onchocerca volvulus Huntingtin homolog 0.0137 0.0312 0.0916
Echinococcus granulosus chromobox protein 1 0.0084 0.0167 0.0167
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0038 0.0153
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0266 0.0657 0.2707
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0014 0.0052
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0001 0.0002
Echinococcus multilocularis peregrin 0.0041 0.0052 0.0052
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0057 0.0094 0.0179
Brugia malayi Immunoglobulin I-set domain containing protein 0.0079 0.0155 0.052
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.0086 0.1113
Schistosoma mansoni hypothetical protein 0.1761 0.4674 0.4674
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0057 0.0094 0.0094
Brugia malayi Sugar transporter family protein 0.0033 0.003 0.0099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0108 0.0233 0.3007
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0007 0.0024
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0035 0.0035
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0132 0.0298 0.0298
Echinococcus granulosus solute carrier family 22 0.0033 0.003 0.003
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.003 0.0382
Plasmodium vivax beta-hydroxyacyl-ACP dehydratase precursor, putative 0.0272 0.0674 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.004 0.0526
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0082 0.0155
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0054 0.0087 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0054 0.0086 0.029
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0167 0.0325
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0157 0.0364 0.0722
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0078 0.0152 0.0152
Echinococcus multilocularis transient receptor potential gamma protein 0.0115 0.0251 0.0251
Echinococcus multilocularis Immunoglobulin 0.006 0.0104 0.0104
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0038 0.0045 0.0152
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.0438
Schistosoma mansoni sugar transporter 0.0033 0.003 0.003
Giardia lamblia DNA repair protein RAD52 0.0393 0.0998 0.1982
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0207 0.0497 0.1674
Schistosoma mansoni nephrin 0.0079 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.006 0.0104 0.0351
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0151 0.1956
Echinococcus multilocularis solute carrier family 22 0.0033 0.003 0.003
Echinococcus granulosus Polycystic kidney disease protein 0.0063 0.011 0.011
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.017 0.04 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Plasmodium falciparum beta-hydroxyacyl-ACP dehydratase 0.0272 0.0674 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0448 0.1147 0.1147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0132 0.0298 0.1003
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0478
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Echinococcus multilocularis caspase 2 0.0094 0.0194 0.0194
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0075 0.0253
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0007 0.0084
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Brugia malayi ImpB/MucB/SamB family protein 0.0211 0.0509 0.1712
Echinococcus granulosus Immunoglobulin 0.006 0.0104 0.0104
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0031 0.0104
Echinococcus granulosus dnaJ subfamily B 0.1761 0.4674 0.4674
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0048 0.0072 0.0271
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0022 0.0079
Trichomonas vaginalis taga, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0035 0.0119
Brugia malayi hypoxia-induced factor 1 0.0165 0.0385 0.1297
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.0773 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0025 0.001 0.001
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0036 0.0144
Onchocerca volvulus 0.0062 0.011 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0152 0.0294
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0036 0.0144
Echinococcus granulosus TRP transient receptor potential channel 0.0046 0.0066 0.0066
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0048 0.0071 0.0071
Schistosoma mansoni nuclear receptor nhr-48 0.0062 0.011 0.011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.0773 1
Brugia malayi Sugar transporter family protein 0.0033 0.003 0.0099
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0024
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0036 0.0133
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0038 0.0129
Loa Loa (eye worm) CHromoDomain protein family member 0.0031 0.0026 0.0088
Trichomonas vaginalis glutaminase, putative 0.0589 0.1525 0.3033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0152 0.0294
Echinococcus multilocularis sodium channel protein 0.0047 0.007 0.007
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0057 0.0094 0.0383
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0038 0.0153
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0026 0.0026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0017 0.0017
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0045 0.0152
Loa Loa (eye worm) CXXC zinc finger family protein 0.0124 0.0274 0.0923
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0157 0.0364 0.0364
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0305 0.0763 0.0763
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0017 0.0063
Brugia malayi major facilitator superfamily protein 0.0033 0.003 0.0099
Brugia malayi Steroid receptor seven-up type 2 0.0132 0.0298 0.1003
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Echinococcus granulosus lysine specific demethylase 6a 0.0074 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0104 0.0222 0.0749
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0011 0.0013
Loa Loa (eye worm) sugar transporter 0.0033 0.003 0.0099
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0017 0.018
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0461 0.1182 0.1182
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0142 0.0478
Schistosoma mansoni nuclear receptor 0.0062 0.011 0.011
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0168 0.0687
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0057 0.0094 0.0094
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0017 0.0063
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0074 0.0962
Onchocerca volvulus Cell death protein 3 homolog 0.0094 0.0194 0.0567
Echinococcus granulosus snurportin 1 0.0337 0.0848 0.0848
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Mycobacterium tuberculosis Probable reductase 0.0239 0.0585 0.2411
Loa Loa (eye worm) glutaminase 2 0.0589 0.1525 0.5133
Echinococcus granulosus peregrin 0.0041 0.0052 0.0052
Echinococcus multilocularis chromobox protein 1 0.0084 0.0167 0.0167
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0049 0.0074 0.0962
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0152 0.1968
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0043 0.0058 0.0058
Echinococcus granulosus caspase 2 0.0094 0.0194 0.0194
Loa Loa (eye worm) RecQ helicase 0.0073 0.0138 0.0463
Schistosoma mansoni glucose transport protein 0.0033 0.003 0.003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0057 0.0094 0.0094
Brugia malayi hypothetical protein 0.0123 0.0272 0.0914
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.0471 0.1941
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trichomonas vaginalis abcb9, putative 0.0057 0.0094 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0093 0.1202
Giardia lamblia DNA damage repair protein 0.0049 0.0073 0.0136
Plasmodium falciparum multidrug resistance protein 1 0.0057 0.0094 0.1339
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.004 0.044
Echinococcus granulosus JmjC domain containing protein 4 0.0074 0.0142 0.0142
Echinococcus granulosus single minded 2 0.0043 0.0058 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0132 0.0298 0.1003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0017 0.0057
Brugia malayi nuclear receptor NHR-88 0.0132 0.0298 0.1003
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0036 0.0144
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0038 0.0551
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.0471 0.0471
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Schistosoma mansoni importin beta-1 0.0032 0.0027 0.0027
Schistosoma mansoni intermediate filament proteins 0.0088 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Schistosoma mansoni cytochrome P450 0.0035 0.0036 0.0036
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.004 0.007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0038 0.0038
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0027 0.0027
Trichomonas vaginalis DNA helicase recq1, putative 0.0073 0.0138 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0123 0.0237
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Schistosoma mansoni hypothetical protein 0.0069 0.0128 0.0128
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0042 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0078 0.0152 0.0152
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0078 0.0152 0.0294
Schistosoma mansoni cell adhesion molecule 0.0099 0.0208 0.0208
Onchocerca volvulus 0.0033 0.003 0.0083
Trypanosoma brucei unspecified product 0.0108 0.0233 0.3009
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0014 0.0183
Entamoeba histolytica hypothetical protein 0.0029 0.0021 0.0039
Schistosoma mansoni hypothetical protein 0.0049 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0024
Brugia malayi hypothetical protein 0.0033 0.003 0.0099
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0033 0.003 0.003
Trypanosoma brucei Metacaspase-4 0.0048 0.0072 0.0935
Schistosoma mansoni neuroglian 0.0038 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi Intermediate filament tail domain containing protein 0.0088 0.0178 0.0598
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0036 0.0144
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.004 0.0158
Brugia malayi Abnormal catecholamine distribution protein 1 0.0207 0.0497 0.1674
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0174 0.0411 0.1556
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0036 0.0038 0.0153
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0168 0.0687
Loa Loa (eye worm) cytochrome P450 family protein 0.0099 0.0207 0.0698
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0103 0.0218 0.0824
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0074 0.0142 0.1837
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0004
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0007 0.0037
Leishmania major p-glycoprotein 0.0057 0.0094 0.1218
Echinococcus granulosus caspase 0.0128 0.0286 0.0286
Leishmania major cytochrome p450-like protein 0.0035 0.0036 0.0468
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0057 0.0094 0.0354
Mycobacterium tuberculosis Probable dehydrogenase 0.0239 0.0585 0.2411
Trypanosoma brucei protein kinase, putative 0.0056 0.0093 0.1202
Echinococcus granulosus caspase 8 0.0048 0.0072 0.0072
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0047 0.007 0.0899
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.0129
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0132 0.0298 0.1003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0063 0.0116
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0017 0.0017
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0033 0.0031 0.0121
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.0039 0.0509
Schistosoma mansoni rab6-interacting 0.0063 0.011 0.011
Schistosoma mansoni smdr2 0.0057 0.0094 0.0094
Onchocerca volvulus 0.0088 0.0178 0.052
Leishmania major phosphoglycerate kinase B, cytosolic 0.0174 0.0411 0.5309
Echinococcus multilocularis roundabout 2 0.0038 0.0045 0.0045
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0052 0.0094
Brugia malayi Flap endonuclease-1 0.0029 0.0019 0.0063
Trypanosoma cruzi metacaspase, putative 0.0048 0.0072 0.0935
Echinococcus multilocularis synaptic vesicular amine transporter 0.0207 0.0497 0.0497
Echinococcus granulosus Chromo domain 0.0024 0.0007 0.0007
Loa Loa (eye worm) beta-lactamase 0.0036 0.0038 0.0129
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0022 0.0022
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0059 0.0763
Brugia malayi major facilitator superfamily protein 0.0033 0.003 0.0099
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.004 0.0514
Echinococcus granulosus neuropeptide receptor A26 0.1036 0.2726 0.2726
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0038 0.0068
Echinococcus multilocularis phd:f box containing protein 0.0074 0.0142 0.0142
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0059 0.0763
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0036 0.0144
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0052 0.0193
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0019 0.0063
Brugia malayi acetyltransferase, GNAT family protein 0.0461 0.1182 0.3977
Onchocerca volvulus 0.0123 0.0272 0.0798
Brugia malayi hypothetical protein 0.0137 0.0312 0.1049
Giardia lamblia Histone acetyltransferase GCN5 0.0124 0.0276 0.0542
Trypanosoma brucei DNA polymerase IV, putative 0.0199 0.0476 0.6154
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0098 0.0207 0.0207
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0036 0.0144
Treponema pallidum fructose-bisphosphate aldolase 0.1889 0.5018 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Brugia malayi hypothetical protein 0.0063 0.011 0.0371
Loa Loa (eye worm) hypothetical protein 0.0123 0.0272 0.0914
Plasmodium vivax multidrug resistance protein 1, putative 0.0057 0.0094 0.138
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0011 0.0011
Echinococcus granulosus multidrug resistance protein 1 0.0057 0.0094 0.0094
Onchocerca volvulus 0.0036 0.0038 0.0109
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0066 0.0119 0.1541
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0052 0.0094
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0036 0.0144
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Mycobacterium tuberculosis Conserved protein 0.0036 0.0038 0.0153
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0014 0.0052
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0151 0.1956
Loa Loa (eye worm) steroid hormone receptor 0.0132 0.0298 0.1003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0036 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0022 0.0074
Brugia malayi multidrug resistance protein 3 0.0057 0.0094 0.0317
Toxoplasma gondii leucyl aminopeptidase LAP 0.0108 0.0233 0.088
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0054 0.0086 0.035
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0036 0.0144
Schistosoma mansoni cell adhesion molecule 0.0038 0.0045 0.0045
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.004 0.007
Schistosoma mansoni hypothetical protein 0.0049 0.0075 0.0075
Echinococcus granulosus expressed protein 0.0067 0.0123 0.0123
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0075 0.0253
Leishmania major glucose transporter, lmgt1 0.0033 0.003 0.0382
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0052 0.0094
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Brugia malayi Importin beta-1 subunit 0.0032 0.0027 0.0091
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0089
Brugia malayi nuclear receptor NHR-88 0.0062 0.011 0.037
Trichomonas vaginalis ABC transporter, putative 0.0057 0.0094 0.0179
Brugia malayi Bromodomain containing protein 0.0041 0.0052 0.0176
Schistosoma mansoni coup transcription factor 0.0132 0.0298 0.0298
Schistosoma mansoni loxhd1 0.0063 0.011 0.011
Echinococcus multilocularis solute carrier family 22 0.0033 0.003 0.003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0152 0.0152
Trichomonas vaginalis chromobox protein, putative 0.0056 0.0091 0.0173
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0132 0.0298 0.0298
Schistosoma mansoni lamin 0.0088 0.0178 0.0178
Brugia malayi nuclear hormone receptor 0.0132 0.0298 0.1003
Schistosoma mansoni tyrosine kinase 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0083 0.0157
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0174 0.0411 0.081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0036 0.0144
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0024
Brugia malayi MAP kinase sur-1 0.0056 0.0093 0.0313
Onchocerca volvulus 0.0047 0.0067 0.0194
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0011 0.0019
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0038 0.0153
Loa Loa (eye worm) oxidoreductase 0.0025 0.0011 0.0036
Schistosoma mansoni hypothetical protein 0.0107 0.023 0.023
Loa Loa (eye worm) nuclear receptor NHR-67 0.0062 0.011 0.037
Leishmania major DNA damage repair protein, putative 0.0049 0.0073 0.0942
Chlamydia trachomatis phosphoglycerate kinase 0.0174 0.0411 0.6034
Entamoeba histolytica recQ family helicase, putative 0.0049 0.0074 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0014 0.0052
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0028 0.0017 0.0056
Schistosoma mansoni hypothetical protein 0.0904 0.2373 0.2373
Chlamydia trachomatis cytosol aminopeptidase 0.0108 0.0233 0.3349
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0053 0.0053
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0007 0.0023
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0048 0.0072 0.0271
Schistosoma mansoni hypothetical protein 0.0049 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0063 0.011 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0073 0.0942
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0047 0.007 0.007
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0001 0.0001
Echinococcus granulosus L aminoadipate semialdehyde 0.0099 0.0207 0.0207
Brugia malayi MH2 domain containing protein 0.0035 0.0035 0.0119
Plasmodium falciparum glutathione reductase 0.0036 0.004 0.0526
Schistosoma mansoni zinc finger protein 0.0062 0.011 0.011
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0036 0.0144
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.004 0.0514
Mycobacterium ulcerans sugar transporter 0.0033 0.003 0.0116
Loa Loa (eye worm) hypothetical protein 0.0049 0.0075 0.0253
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0007 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0132 0.0298 0.0298
Echinococcus multilocularis expressed protein 0.0409 0.1041 0.1041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Onchocerca volvulus 0.0033 0.003 0.0083
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0045 0.0063 0.0063
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.004 0.0526
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0166 0.0388 0.0388
Trypanosoma brucei DNA polymerase IV, putative 0.0212 0.0513 0.6634
Brugia malayi Sugar transporter family protein 0.0033 0.003 0.0099
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0174 0.0411 0.1556
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0108 0.0233 0.3007
Schistosoma mansoni caspase-3 (C14 family) 0.0128 0.0286 0.0286
Brugia malayi PHD-finger family protein 0.003 0.0022 0.0074
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0084 0.0168 0.0565
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0036 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0122 0.027 0.3489
Loa Loa (eye worm) hypothetical protein 0.0042 0.0056 0.0188
Brugia malayi hypothetical protein 0.0033 0.003 0.0099
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0036 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0222 0.2876
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0062 0.011 0.011
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0038 0.0153
Echinococcus multilocularis ATP binding cassette sub family B 0.0056 0.0093 0.0093
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1889 0.5018 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0152 0.0294
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0142 0.0142
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0039 0.0157
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0132 0.0298 0.1003
Onchocerca volvulus 0.0033 0.003 0.0083
Echinococcus granulosus RUN 0.0063 0.011 0.011
Brugia malayi glutaminase DH11.1 0.0589 0.1525 0.5133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.0558 0.2298
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0174 0.0411 0.1691
Schistosoma mansoni hypothetical protein 0.0029 0.0021 0.0021
Leishmania major protein kinase, putative 0.0027 0.0015 0.0195
Trichomonas vaginalis set domain proteins, putative 0.1282 0.3388 0.6749
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.004 0.0514
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Leishmania major importin beta-1 subunit, putative 0.0026 0.0011 0.0141
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0014 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.004 0.057
Mycobacterium ulcerans lipase LipD 0.0036 0.0038 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0036 0.0144
Brugia malayi Nuclear hormone receptor E75 0.0062 0.011 0.037
Echinococcus multilocularis phosphoglycerate kinase 1 0.0174 0.0411 0.0411
Trichomonas vaginalis rotamase, putative 0.0067 0.0123 0.0237
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0001 0.0015
Trypanosoma brucei metacaspase 5, putative 0.0048 0.0072 0.0935
Trichomonas vaginalis abcb9, putative 0.0057 0.0094 0.0179
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0284 0.0704 0.9104
Schistosoma mansoni DNA polymerase IV / kappa 0.0049 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0099 0.0207 0.0697
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.004 0.0147
Echinococcus granulosus roundabout 2 0.0038 0.0045 0.0045
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0036 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.0471 0.1941
Plasmodium falciparum flap endonuclease 1 0.0029 0.0019 0.0212
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0057 0.0094 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0132 0.0298 0.0298
Onchocerca volvulus Phospholipase A2 homolog 0.0355 0.0896 0.2641
Trypanosoma brucei phosphoglycerate kinase 0.0174 0.0411 0.5309
Brugia malayi ecdysone receptor 0.0062 0.011 0.037
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0284 0.0704 0.9104
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Giardia lamblia Sugar-proton symporter 0.0033 0.003 0.005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0093 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0132 0.0298 0.1003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0132 0.0298 0.1003
Plasmodium falciparum LCCL domain-containing protein 0.0063 0.011 0.1578
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0007 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.038 0.1564
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0043 0.0058 0.0797
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0054 0.0087 0.0087
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0112 0.0243 0.0481
Brugia malayi Glycosyl hydrolases family 31 protein 0.0184 0.0437 0.1471
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0007 0.0005
Trypanosoma cruzi DNA damage repair protein, putative 0.0049 0.0073 0.0942
Echinococcus granulosus transient receptor potential gamma protein 0.0115 0.0251 0.0251
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0036 0.0144
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0052 0.0101
Brugia malayi hypothetical protein 0.0079 0.0155 0.052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0132 0.0298 0.0298
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0336 0.4338
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0048 0.0071 0.0915
Schistosoma mansoni hypothetical protein 0.003 0.0022 0.0022
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0197 0.0471 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus granulosus neuroglian 0.0038 0.0045 0.0045
Trypanosoma brucei metacaspase MCA3 0.0048 0.0072 0.0935
Loa Loa (eye worm) hypothetical protein 0.0078 0.0152 0.0512
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0203 0.0597
Brugia malayi follicle stimulating hormone receptor 0.0775 0.2024 0.6812
Echinococcus multilocularis basement membrane specific heparan sulfate 0.006 0.0104 0.0104
Brugia malayi Protein cec-1. 0.0024 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0079 0.0155 0.052
Leishmania major hypothetical protein, conserved 0.0033 0.003 0.0382
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0025 0.0011 0.0089
Mycobacterium ulcerans hypothetical protein 0.0163 0.038 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Brugia malayi SET domain containing protein 0.0035 0.0036 0.0121
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0093 0.1202
Trichomonas vaginalis hypothetical protein 0.0024 0.0007 0.0005
Entamoeba histolytica hypothetical protein 0.0029 0.0021 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0073 0.0942
Loa Loa (eye worm) intermediate filament protein 0.0088 0.0178 0.0598
Echinococcus granulosus Peptidase C54 0.0048 0.0071 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.0172 0.0579
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0239 0.0585 0.2411
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0132 0.0298 0.1003
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0038 0.0497
Loa Loa (eye worm) cytochrome P450 0.0035 0.0036 0.0122
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0198 0.0474 0.1952
Mycobacterium ulcerans beta-lactamase 0.0036 0.0038 0.0153
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0151 0.0151
Mycobacterium leprae putative cytochrome p450 0.0035 0.0036 0.0144
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0005 0.0059
Trypanosoma cruzi hexose transporter 0.0033 0.003 0.0382
Trichomonas vaginalis helicase, putative 0.0028 0.0017 0.0026
Brugia malayi hypothetical protein 0.0063 0.011 0.0371
Leishmania major trypanothione reductase 0.0105 0.0224 0.2895
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0198 0.0474 0.1952
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.007 0.013 0.013
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0048 0.0071 0.0132
Schistosoma mansoni cpg binding protein 0.0131 0.0293 0.0293
Schistosoma mansoni alpha-glucosidase 0.0159 0.0368 0.0368
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0038 0.0068
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0166 0.0388 0.0388
Trypanosoma brucei DNA damage repair protein, putative 0.0049 0.0073 0.0942
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0036 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0132 0.0298 0.0298
Onchocerca volvulus 0.0057 0.0094 0.0274
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.011 0.011
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0028 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0018 0.0027
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0923 0.2422 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0066 0.0119 0.1541
Plasmodium vivax glutathione reductase, putative 0.0105 0.0224 0.331
Leishmania major hypothetical protein, conserved 0.0074 0.0142 0.1837
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0067 0.0123 0.0415
Entamoeba histolytica hypothetical protein 0.0028 0.0017 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0021 0.0021
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0098 0.0207 0.0207
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0074 0.0142 0.0536
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.0438
Schistosoma mansoni hypothetical protein 0.0033 0.003 0.003
Onchocerca volvulus 0.0124 0.0274 0.0806
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0132 0.0298 0.1003
Schistosoma mansoni lipoxygenase 0.0305 0.0763 0.0763
Chlamydia trachomatis endonuclease IV 0.0084 0.0168 0.2371
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0019 0.0028
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0022 0.0074
Mycobacterium leprae Probable lipase LipE 0.0036 0.0038 0.0153
Brugia malayi N-terminal motif family protein 0.0337 0.0847 0.2852
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.004 0.0514
Echinococcus multilocularis synaptic vesicle 2 protein 0.0033 0.0031 0.0031
Echinococcus granulosus roundabout 2 0.0038 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0062 0.011 0.037
Schistosoma mansoni nephrin 0.0038 0.0045 0.0045
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.034 0.0857 0.0857
Brugia malayi hypothetical protein 0.0524 0.1351 0.4548
Brugia malayi orphan nuclear receptor NR2E1 0.0062 0.011 0.037
Schistosoma mansoni jumonji domain containing protein 0.032 0.0803 0.0803
Toxoplasma gondii beta-hydroxyacyl-acyl carrier protein dehydratase (FABZ) 0.0272 0.0674 0.2556
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0007 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0086 0.029
Loa Loa (eye worm) hypothetical protein 0.0137 0.0312 0.1049
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0035 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Entamoeba histolytica acetyltransferase, GNAT family 0.0124 0.0276 0.0549
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0136 0.0307 0.4542
Echinococcus multilocularis ubiquitin specific protease 41 0.0078 0.0152 0.0152
Entamoeba histolytica P-glycoprotein-2, putative 0.0057 0.0094 0.0185
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0132 0.0298 0.1003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0033 0.003 0.0116
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0128 0.0286 0.0286
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0337 0.0848 0.2855
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0005 0.0005
Schistosoma mansoni thyroid hormone receptor 0.0132 0.0298 0.0298
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0007 0.0005
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.0074 0.0139
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0057 0.0094 0.0179
Schistosoma mansoni survival motor neuron protein 0.0107 0.023 0.023
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0038 0.0153
Schistosoma mansoni protein phosphatase 2C 0.0074 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0088 0.0178 0.0598
Schistosoma mansoni hypothetical protein 0.0904 0.2373 0.2373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0025 0.0011 0.0137
Toxoplasma gondii histone lysine methyltransferase SET1 0.0254 0.0624 0.2366
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0047 0.007 0.007
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0093 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Onchocerca volvulus Huntingtin homolog 0.0137 0.0312 0.0916
Echinococcus multilocularis Peptidase C54 0.0048 0.0071 0.0071
Echinococcus granulosus thyroid hormone receptor alpha 0.0062 0.011 0.011
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0011 0.0038
Loa Loa (eye worm) thioredoxin reductase 0.0105 0.0224 0.0754
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0166 0.0388 0.1469
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.011 0.011
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0212 0.0513 0.1014
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Trichomonas vaginalis glucose transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0166 0.0387 0.1302
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0025 0.0011 0.0011
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0284 0.0704 0.237
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0197 0.0471 0.1941
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0036 0.0144
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0014 0.0052
Echinococcus granulosus twitchin 0.0061 0.0107 0.0107
Leishmania major DNA polymerase eta, putative 0.0211 0.0509 0.6576
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0336 0.4338
Echinococcus multilocularis solute carrier family 22 0.0033 0.003 0.003
Onchocerca volvulus 0.0107 0.023 0.0674
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0036 0.0144
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0364 0.1496
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0033 0.003 0.003
Onchocerca volvulus 0.0033 0.003 0.0083
Brugia malayi Doublecortin family protein 0.0063 0.011 0.0371
Echinococcus multilocularis 0.0035 0.0036 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0073 0.0942
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0007 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Schistosoma mansoni nuclear receptor 0.0062 0.011 0.011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0166 0.0388 0.0388
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0005 0.0047
Brugia malayi beta-lactamase 0.0036 0.0038 0.0129
Schistosoma mansoni hypothetical protein 0.0049 0.0075 0.0075
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0048 0.0071 0.0915
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Schistosoma mansoni microtubule-associated protein tau 0.3743 1 1
Echinococcus granulosus bloom syndrome protein 0.0073 0.0138 0.0138
Echinococcus multilocularis FTZ F1 alpha 0.0132 0.0298 0.0298
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0048 0.0072 0.0271
Loa Loa (eye worm) hypothetical protein 0.0057 0.0094 0.0317
Brugia malayi Peptidase family C54 containing protein 0.0048 0.0071 0.0238
Echinococcus granulosus histone lysine methyltransferase setb 0.0166 0.0388 0.0388
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.1001 0.2632 1
Giardia lamblia Hexose transporter 0.0033 0.003 0.005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0036 0.0468
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0038 0.0153
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0025 0.0011 0.0038
Brugia malayi hypothetical protein 0.007 0.013 0.0438
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0062 0.011 0.011
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0081 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0211 0.0509 0.1712
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0007 0.0012
Leishmania major oxidoreductase-like protein 0.0036 0.0039 0.0509
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.003 0.0099
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.004 0.004
Plasmodium vivax multidomain scavenger receptor, putative 0.0063 0.011 0.1617
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.004 0.004
Brugia malayi intermediate filament protein 0.0088 0.0178 0.0598
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0093 0.0176
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0036 0.0468
Trypanosoma brucei DNA polymerase eta, putative 0.0211 0.0509 0.6576
Plasmodium vivax sugar transporter, putative 0.0033 0.003 0.0419
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0046 0.0046
Echinococcus multilocularis Immunoglobulin 0.006 0.0104 0.0104
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi Cell death protein 3 precursor 0.0094 0.0194 0.0652
Echinococcus granulosus dna polymerase kappa 0.0212 0.0513 0.0513
Trypanosoma brucei unspecified product 0.0199 0.0476 0.6154
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0028 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0036 0.0144
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0197 0.0471 0.6091
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0047 0.007 0.007
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0151 0.0151
Schistosoma mansoni single-minded 0.0053 0.0085 0.0085
Entamoeba histolytica hypothetical protein 0.0112 0.0243 0.0481
Trypanosoma cruzi trypanothione reductase, putative 0.0105 0.0224 0.2895
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0168 0.0565
Echinococcus granulosus roundabout 2 0.0099 0.0208 0.0208
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0048 0.0071 0.0132
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0025 0.0011 0.0036
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0136 0.0307 0.1161
Schistosoma mansoni phosphoglycerate kinase 0.0174 0.0411 0.0411
Mycobacterium ulcerans hypothetical protein 0.0036 0.0038 0.0153
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0048 0.0072 0.0072
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Plasmodium vivax thioredoxin reductase, putative 0.0105 0.0224 0.331
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0054 0.0087 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0036 0.0144
Onchocerca volvulus 0.0132 0.0298 0.0876
Onchocerca volvulus 0.0123 0.0272 0.0798
Loa Loa (eye worm) Smad1 0.0035 0.0035 0.0119
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0093 0.1202
Schistosoma mansoni chromobox protein 0.0024 0.0007 0.0007
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0019 0.0028
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0284 0.0704 0.9104
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0203 0.2631
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0025 0.0011 0.0137
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0156 0.0362 0.1219
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0142 0.0478
Loa Loa (eye worm) glutaminase 0.0589 0.1525 0.5133
Schistosoma mansoni ephrin receptor 0.0024 0.0007 0.0007
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0239 0.0585 0.2411
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0019 0.0035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0057 0.0094 0.0179
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0093 0.1202
Schistosoma mansoni caspase-7 (C14 family) 0.0128 0.0286 0.0286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0031 0.0026 0.0342
Schistosoma mansoni transient receptor potential channel 0.0078 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0036 0.0144
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.007 0.013 0.013
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0038 0.0153
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0057 0.0094 0.1261
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0198 0.0474 0.1595
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0075 0.0253
Schistosoma mansoni kinase 0.005 0.0076 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0036 0.0144
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0019 0.0243
Schistosoma mansoni ran 0.0023 0.0005 0.0005
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0014 0.0052
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0081 0.0161 0.0161
Echinococcus multilocularis caspase 3 0.008 0.0156 0.0156
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0052 0.0672
Trypanosoma brucei polo-like protein kinase 0.0097 0.0203 0.2631
Loa Loa (eye worm) nuclear hormone receptor 0.0062 0.011 0.037
Trypanosoma brucei metacaspase 0.0048 0.0072 0.0935
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0028 0.0017 0.0017
Trypanosoma cruzi hexose transporter, putative 0.0033 0.003 0.0382
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0336 0.4338
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0136 0.0307 0.1161
Echinococcus granulosus ecdysone induced protein 78C 0.0132 0.0298 0.0298
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0019 0.0243
Onchocerca volvulus 0.0063 0.011 0.0321
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0042 0.0075
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0116 0.0253 0.0852
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0048 0.0072 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0083 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0011 0.0038
Schistosoma mansoni sugar transporter 0.0033 0.003 0.003
Trypanosoma brucei DNA damage repair protein, putative 0.0049 0.0073 0.0942
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Onchocerca volvulus 0.0036 0.0038 0.0109
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0062 0.011 0.011
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Plasmodium falciparum phd finger protein, putative 0.003 0.0022 0.0259
Trypanosoma cruzi metacaspase, putative 0.0048 0.0072 0.0935
Schistosoma mansoni polycystin 1-related 0.0063 0.011 0.011
Echinococcus granulosus multidrug resistance protein 1 0.0057 0.0094 0.0094
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.003 0.0099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0038 0.0129
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0074 0.0142 0.0142
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0014 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0122 0.027 0.3489
Wolbachia endosymbiont of Brugia malayi (3R)-hydroxymyristoyl-ACP dehydratase 0.0272 0.0674 1
Brugia malayi Cytochrome P450 family protein 0.0099 0.0207 0.0698
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0083 0.0241
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0088 0.0178 0.0598
Entamoeba histolytica P-glyco protein 6, putative 0.0057 0.0094 0.0185
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0203 0.2631
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0017 0.0017
Echinococcus multilocularis cpg binding protein 0.0131 0.0293 0.0293
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0132 0.0298 0.0298
Echinococcus multilocularis lamin dm0 0.0088 0.0178 0.0178
Schistosoma mansoni chromobox protein 0.0084 0.0167 0.0167
Schistosoma mansoni nuclear hormone receptor 0.0062 0.011 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Brugia malayi Bloom's syndrome protein homolog 0.0073 0.0138 0.0463
Echinococcus multilocularis thyroid hormone receptor alpha 0.0132 0.0298 0.0298
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0142 0.0478
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0031 0.0026 0.0026
Schistosoma mansoni glucose transport protein 0.0033 0.003 0.003
Entamoeba histolytica P-glycoprotein-1 0.0057 0.0094 0.0185
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0001 0.0002
Trypanosoma cruzi metacaspase, putative 0.0048 0.0072 0.0935
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0001 0.0002
Echinococcus granulosus intermediate filament protein 0.0088 0.0178 0.0178
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0152 0.0152
Echinococcus granulosus transcription factor Dp 1 0.0164 0.0383 0.0383
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.019 0.0453 0.0453
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0007 0.0005
Entamoeba histolytica hypothetical protein 0.0029 0.0021 0.0039
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0017 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.001 0.001
Brugia malayi Cytochrome P450 family protein 0.0054 0.0086 0.029
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0062 0.011 0.037
Plasmodium falciparum histone acetyltransferase GCN5 0.0124 0.0276 0.4062
Plasmodium falciparum DNA repair protein REV1, putative 0.0049 0.0073 0.1021
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0036 0.0144
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0151 0.0151
Echinococcus multilocularis dnaJ subfamily B 0.1761 0.4674 0.4674
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0074 0.0142 0.1837
Brugia malayi hypothetical protein 0.0029 0.0021 0.0069
Trichomonas vaginalis glucose transporter, putative 0.0033 0.003 0.005
Brugia malayi hypothetical protein 0.007 0.013 0.0438
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0046 0.0066 0.0066
Plasmodium vivax SET domain protein, putative 0.0073 0.0137 0.2023
Plasmodium vivax phosphoglycerate kinase, putative 0.0174 0.0411 0.6088
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.0114 0.1475
Plasmodium vivax hexose transporter 0.0033 0.003 0.0419
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0093 0.0093
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0019 0.0067
Echinococcus granulosus Solute carrier family 22 5 0.2293 0.6104 0.6104
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0025 0.0011 0.0038
Trichomonas vaginalis chromobox protein, putative 0.0056 0.0091 0.0173
Loa Loa (eye worm) hypothetical protein 0.0056 0.0093 0.0311
Leishmania major DNA polymerase eta, putative 0.0103 0.0218 0.2819
Echinococcus granulosus defective proboscis extension response 0.006 0.0104 0.0104
Trichomonas vaginalis abcb9, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0048
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0007 0.0084
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.0094 0.0317
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0043 0.0058 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0036 0.0144
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0036 0.0039 0.0157
Trichomonas vaginalis esterase, putative 0.0036 0.0038 0.0068
Schistosoma mansoni thyroid hormone receptor 0.0132 0.0298 0.0298
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0025 0.0011 0.0038
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.002
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0108 0.0233 0.0955
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0266 0.0657 0.2707
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0059 0.0763
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0057 0.0094 0.0094
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0027 0.0098
Echinococcus multilocularis multidrug resistance protein 1 0.0057 0.0094 0.0094
Leishmania major DNA polymerase kappa, putative 0.0049 0.0073 0.0942
Echinococcus multilocularis expressed protein 0.0067 0.0123 0.0123
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0058 0.0216
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0203 0.0203
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.011 0.011
Onchocerca volvulus 0.0166 0.0387 0.1138
Loa Loa (eye worm) hypothetical protein 0.0069 0.0127 0.0428
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0039 0.0047 0.016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0173
Brugia malayi Phosphoglycerate kinase 0.0174 0.0411 0.1382
Echinococcus granulosus dna polymerase eta 0.0211 0.0509 0.0509
Entamoeba histolytica hypothetical protein 0.0029 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0086 0.0173 0.0583
Brugia malayi conserved hypotetical protein 0.0062 0.011 0.037
Echinococcus granulosus chromobox protein 1 0.0084 0.0167 0.0167
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0033 0.003 0.0287
Loa Loa (eye worm) hypothetical protein 0.0073 0.0137 0.0462
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.011 0.0321
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0005 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0014 0.0052
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0073 0.0137 0.0137
Echinococcus granulosus sodium channel protein 0.0047 0.007 0.007
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0021 0.0021
Toxoplasma gondii aldehyde dehydrogenase 0.0197 0.0471 0.1786
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0284 0.0704 0.1401
Loa Loa (eye worm) hypothetical protein 0.0524 0.1351 0.4548
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0168 0.2474
Echinococcus granulosus ubiquitin specific protease 41 0.0078 0.0152 0.0152
Trypanosoma brucei phosphoglycerate kinase 0.0174 0.0411 0.5309
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Echinococcus multilocularis lamin 0.0088 0.0178 0.0178
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0024 0.0007 0.0007
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0198 0.0474 0.6128
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Loa Loa (eye worm) hypothetical protein 0.0063 0.011 0.0371
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.004 0.0514
Loa Loa (eye worm) hypothetical protein 0.0337 0.0847 0.2852
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0066 0.0119 0.0235
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0132 0.0298 0.0298
Schistosoma mansoni Smad4 0.0035 0.0035 0.0035
Schistosoma mansoni terminal deoxycytidyl transferase 0.0157 0.0364 0.0364
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0062 0.011 0.0414
Plasmodium vivax importin-beta 2, putative 0.0032 0.0027 0.038
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0014 0.0048
Echinococcus granulosus synaptic vesicle 2 protein 0.0033 0.0031 0.0031
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.008 0.0157 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Schistosoma mansoni multidrug resistance protein 0.0057 0.0094 0.0094
Echinococcus granulosus solute carrier family 22 0.0033 0.003 0.003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.004 0.0158
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.0438
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0038 0.0068
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0152 0.1968
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0143
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0007 0.0037
Loa Loa (eye worm) helicase 0.0024 0.0007 0.0024
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0012
Schistosoma mansoni multidrug resistance protein 0.0057 0.0094 0.0094
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0012
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0046 0.0046
Brugia malayi Phosphoglycerate kinase 0.0064 0.0114 0.0384
Schistosoma mansoni jumonji/arid domain-containing protein 0.0286 0.0711 0.0711
Echinococcus multilocularis geminin 0.0904 0.2373 0.2373
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0007 0.0005
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.003 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0132 0.0298 0.1003
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0047 0.007 0.007
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0011 0.0038
Brugia malayi Fibronectin type III domain containing protein 0.0079 0.0155 0.052
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0036 0.0144
Echinococcus multilocularis roundabout 2 0.0099 0.0208 0.0208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi glutathione reductase 0.0105 0.0224 0.0754
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.003 0.0382
Echinococcus granulosus lysine specific demethylase 5A 0.0286 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0047 0.0086
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0039 0.0157
Brugia malayi MH2 domain containing protein 0.0509 0.1311 0.4413
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0197 0.0471 0.0471
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0284 0.0704 0.0704
Loa Loa (eye worm) hypothetical protein 0.0355 0.0896 0.3015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0171 0.0401 0.1649
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Plasmodium falciparum metacaspase-like protein 0.0048 0.0072 0.1013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0039 0.0157
Brugia malayi MH1 domain containing protein 0.0035 0.0035 0.0119
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0198 0.0474 0.0474
Echinococcus granulosus voltage gated potassium channel 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.008 0.0157 0.053
Brugia malayi jmjC domain containing protein 0.034 0.0857 0.2884
Echinococcus multilocularis Smad4 0.0035 0.0035 0.0035
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0171 0.0401 0.518
Brugia malayi hypothetical protein 0.0033 0.003 0.0099
Trypanosoma cruzi DNA damage repair protein, putative 0.0049 0.0073 0.0942
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.003 0.0099
Toxoplasma gondii sugar transporter ST2 0.0033 0.003 0.0108
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0011 0.0038
Mycobacterium ulcerans DNA polymerase IV 0.0212 0.0513 0.2114
Schistosoma mansoni DNA helicase recq5 0.0043 0.0058 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0036 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0132 0.0298 0.1003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0047 0.0086
Brugia malayi jmjC domain containing protein 0.0074 0.0142 0.0478
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0393 0.0998 0.1988
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0035 0.0035
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0007 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0078 0.0152 0.0301
Loa Loa (eye worm) hypoxia-induced factor 1 0.0165 0.0385 0.1297
Onchocerca volvulus 0.0033 0.003 0.0083
Brugia malayi Calcitonin receptor-like protein seb-1 0.0156 0.0362 0.1219
Trypanosoma cruzi glucose transporter, putative 0.0033 0.003 0.0382
Brugia malayi Pre-SET motif family protein 0.1127 0.2971 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0079 0.0155 0.052
Entamoeba histolytica P-glycoprotein-2 0.0057 0.0094 0.0185
Entamoeba histolytica peptidase, C54 family 0.0048 0.0071 0.0139
Onchocerca volvulus 0.019 0.0453 0.1333
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0067 0.0123 0.0415
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0038 0.0045 0.0152
Echinococcus multilocularis cysteine protease atg4b 0.0048 0.0071 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.013 0.013
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0017 0.0091
Plasmodium vivax JmjC domain containing protein 0.0074 0.0142 0.2093
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0074 0.0142 0.0536
Schistosoma mansoni cpg binding protein 0.0131 0.0293 0.0293
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0017 0.0059
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0046 0.0067 0.0067
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0031 0.0026 0.0342
Trypanosoma cruzi metacaspase, putative 0.0048 0.0072 0.0935
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0203 0.0403
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0043 0.0058 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0203 0.0203
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0266 0.0657 0.2707
Onchocerca volvulus 0.0045 0.0063 0.0183
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Schistosoma mansoni rab6-interacting 0.0063 0.011 0.011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0132 0.0298 0.0298
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.004 0.0158
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0174 0.0411 0.1691
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0048 0.0071 0.0071
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0011 0.0038
Leishmania major phosphoglycerate kinase C, glycosomal 0.0174 0.0411 0.5309
Trypanosoma cruzi DNA polymerase eta, putative 0.0103 0.0218 0.2819
Brugia malayi jmjC domain containing protein 0.0286 0.0711 0.2393
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0057 0.0094 0.0179
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0036 0.0144
Brugia malayi jmjC domain containing protein 0.0074 0.0142 0.0478
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0114 0.1475
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0062 0.0232
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.0471 0.0471
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0132 0.0298 0.1003
Trypanosoma brucei DNA polymerase kappa, putative 0.0171 0.0401 0.518
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0042 0.0143
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0052 0.0094
Brugia malayi hypothetical protein 0.0045 0.0063 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0052 0.0672
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Onchocerca volvulus 0.0062 0.011 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Loa Loa (eye worm) acetyltransferase 0.0461 0.1182 0.3977
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.013 0.0438
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0284 0.0704 0.0704
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0052 0.0052
Echinococcus multilocularis caspase 8 0.0048 0.0072 0.0072
Giardia lamblia Phosphoglycerate kinase 0.0174 0.0411 0.081
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0048 0.0162
Schistosoma mansoni caspase-7 (C14 family) 0.0094 0.0194 0.0194
Echinococcus multilocularis apoptotic protease activating factor 1 0.0045 0.0063 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0132 0.0298 0.0298
Brugia malayi chromobox protein homolog 3 0.0052 0.0083 0.028
Brugia malayi hypothetical protein 0.0179 0.0423 0.1422
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0923 0.2422 1
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Echinococcus multilocularis Polycystic kidney disease protein 0.0063 0.011 0.011
Trichomonas vaginalis glucose transporter, putative 0.0033 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0053 0.0179
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0078 0.0151 0.1956
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0045 0.0064 0.0936
Schistosoma mansoni autophagin-1 (C54 family) 0.0048 0.0071 0.0071
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0156 0.0362 0.1219
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0036 0.0144
Chlamydia trachomatis 3-hydroxyacyl-ACP dehydratase 0.0272 0.0674 1
Echinococcus multilocularis transcription factor Dp 1 0.0164 0.0383 0.0383
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0091 0.0307
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0033 0.003 0.0382
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0038 0.0497
Entamoeba histolytica P-glycoprotein 5, putative 0.0057 0.0094 0.0185
Loa Loa (eye worm) hypothetical protein 0.0123 0.0272 0.0914
Plasmodium vivax SET domain protein, putative 0.0166 0.0388 0.5748
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0048 0.0071 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0052 0.0672
Giardia lamblia Sgs1 DNA helicase, putative 0.0043 0.0058 0.0106
Echinococcus granulosus GPCR family 2 0.0049 0.0075 0.0075
Plasmodium falciparum thioredoxin reductase 0.0036 0.004 0.0526
Schistosoma mansoni hypothetical protein 0.0107 0.0229 0.0229
Entamoeba histolytica phosphoglycerate kinase, putative 0.0174 0.0411 0.0816
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0038 0.0497
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0038 0.0068
Brugia malayi Protein-tyrosine phosphatase 0.0028 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0179 0.0423 0.1422
Brugia malayi Nuclear hormone receptor-like 1 0.0132 0.0298 0.1003
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0038 0.0038
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0035 0.0035
Brugia malayi Heterochromatin protein 1 0.0084 0.0167 0.0564
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0014 0.0048
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0046 0.0067 0.0067
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0132 0.0298 0.0298
Trypanosoma brucei oxidoreductase-like protein 0.0036 0.0039 0.0509
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0072 0.0135
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0052 0.0175
Onchocerca volvulus 0.0033 0.003 0.0083
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0022 0.0079
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0036 0.0144
Mycobacterium ulcerans endonuclease IV 0.0084 0.0168 0.0687
Echinococcus multilocularis dna polymerase eta 0.0211 0.0509 0.0509
Loa Loa (eye worm) glutathione reductase 0.0105 0.0224 0.0754
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0014 0.0052
Schistosoma mansoni glucose transporter 0.0033 0.003 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0045 0.0152
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0005 0.0015
Plasmodium falciparum hexose transporter 0.0033 0.003 0.0373
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0108 0.0233 0.3439
Onchocerca volvulus 0.0088 0.0178 0.052
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0017 0.0226
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0054 0.0087 0.0292
Schistosoma mansoni blooms syndrome DNA helicase 0.0051 0.0079 0.0079
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0093 0.0093
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0057 0.0094 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0052 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus multilocularis lysosomal alpha glucosidase 0.0184 0.0437 0.0437
Trichomonas vaginalis myo-inositol transporter, putative 0.0033 0.003 0.005
Brugia malayi Nuclear hormone receptor E75 0.0062 0.011 0.037
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0033 0.003 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.004 0.057
Toxoplasma gondii hypothetical protein 0.005 0.0076 0.0285
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0057 0.0094 0.0094
Toxoplasma gondii histone lysine methyltransferase SET8 0.0073 0.0137 0.0518
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.0773 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0017 0.0017
Loa Loa (eye worm) jmjC domain-containing protein 0.0286 0.0711 0.2393
Leishmania major glucose transporter, lmgt2 0.0033 0.003 0.0382
Echinococcus granulosus solute carrier family 22 0.0033 0.003 0.003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0085 0.1093
Echinococcus granulosus flap endonuclease 1 0.0029 0.0019 0.0019
Echinococcus multilocularis leucine aminopeptidase protein 0.0108 0.0233 0.0233
Schistosoma mansoni jumonji/arid domain-containing protein 0.0286 0.0711 0.0711
Echinococcus granulosus expressed protein 0.0409 0.1041 0.1041
Trypanosoma cruzi hexose transporter, putative 0.0033 0.003 0.0382
Leishmania major myo-inositol/proton symporter (MIT) 0.0033 0.003 0.0382
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0132 0.0298 0.1003
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0174 0.0411 0.1382
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0028 0.0017 0.0017
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.004 0.0147
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0049 0.0073 0.0273
Echinococcus multilocularis thioredoxin glutathione reductase 0.0105 0.0224 0.0224
Schistosoma mansoni smad1 5 8 and 0.0035 0.0035 0.0035
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0048 0.0071 0.0915
Loa Loa (eye worm) hypothetical protein 0.0043 0.0058 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.007 0.013 0.0438
Onchocerca volvulus 0.0033 0.003 0.0083
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0022 0.0022
Brugia malayi cytoplasmic intermediate filament protein 0.0047 0.0068 0.023
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0039 0.0048 0.0087
Echinococcus granulosus leucine aminopeptidase protein 0.0108 0.0233 0.0233
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0052 0.0094
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0184 0.0437 0.1471
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.003 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0042 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0305 0.0763 0.0763
Schistosoma mansoni multidrug resistance protein 0.0057 0.0094 0.0094
Onchocerca volvulus 0.0036 0.0038 0.0109
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0057 0.0094 0.0354
Trypanosoma brucei DNA polymerase IV, putative 0.0212 0.0513 0.6634
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0057 0.0094 0.0179
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0036 0.0144
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0043 0.0058 0.0058
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0025 0.001 0.0033
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0048 0.0071 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0042 0.0042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0014 0.0047
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Leishmania major metacaspase, putative 0.0048 0.0072 0.0935
Echinococcus granulosus solute carrier family 22 0.0033 0.003 0.003
Echinococcus multilocularis RUN 0.0063 0.011 0.011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.011 0.011
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0108 0.0233 0.0955
Trichomonas vaginalis DNA helicase recq, putative 0.0073 0.0138 0.0265
Schistosoma mansoni smad 0.0035 0.0035 0.0035
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0042 0.0143
Treponema pallidum NADH oxidase 0.0036 0.004 0.0077
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0086 0.029
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0284 0.0704 0.9104
Toxoplasma gondii sugar transporter ST3 0.0033 0.003 0.0108
Loa Loa (eye worm) hypothetical protein 0.0075 0.0143 0.0481
Echinococcus granulosus neuroglian 0.006 0.0104 0.0104
Mycobacterium ulcerans phosphoglycerate kinase 0.0174 0.0411 0.1691
Echinococcus multilocularis GPCR, family 2 0.0049 0.0075 0.0075
Brugia malayi Thioredoxin reductase 0.0105 0.0224 0.0754
Loa Loa (eye worm) hypothetical protein 0.0115 0.0251 0.0846
Plasmodium falciparum thioredoxin reductase 0.0105 0.0224 0.3278
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Onchocerca volvulus 0.0031 0.0026 0.0074
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0132 0.0298 0.0298
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0229 0.0772
Echinococcus granulosus transient receptor potential ion channel A 0.0106 0.0227 0.0227
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0038 0.0045 0.0045
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0011 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0062 0.011 0.037
Brugia malayi Cytochrome P450 family protein 0.0054 0.0086 0.029
Mycobacterium ulcerans hypothetical protein 0.0027 0.0014 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0079 0.0155 0.052
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0132 0.0298 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0072 0.0135
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0025 0.0011 0.0036
Echinococcus multilocularis transient receptor potential ion channel A 0.0106 0.0227 0.0227
Echinococcus granulosus importin subunit beta 1 0.0032 0.0027 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.027 0.0669 0.0669
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0025 0.0011 0.0011
Brugia malayi Muscleblind-like protein 0.0153 0.0353 0.1189
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0005 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0026
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0152 0.1968
Onchocerca volvulus 0.0033 0.003 0.0083
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0048 0.0071 0.0132
Schistosoma mansoni alpha glucosidase 0.0041 0.0052 0.0052
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0152 0.1968
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0033 0.003 0.003
Onchocerca volvulus 0.0033 0.003 0.0083
Schistosoma mansoni phosphoglycerate kinase 0.0174 0.0411 0.0411
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0048 0.0072 0.0243
Schistosoma mansoni smad1 5 8 and 0.0035 0.0035 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0093 0.0176
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0167 0.0564
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0058 0.0195
Loa Loa (eye worm) sugar transporter 0.0033 0.003 0.0099
Treponema pallidum phosphoglycerate kinase 0.0174 0.0411 0.0816
Entamoeba histolytica Ran family GTPase 0.0023 0.0005 0.0007
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0337 0.0847 0.2498
Brugia malayi polk-prov protein 0.0104 0.0222 0.0749
Echinococcus granulosus thioredoxin glutathione reductase 0.0105 0.0224 0.0224
Schistosoma mansoni retinoic acid receptor RXR 0.024 0.0588 0.0588
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0108 0.0233 0.3349
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Mycobacterium ulcerans glutaminase 0.0589 0.1525 0.6296
Echinococcus multilocularis dna polymerase kappa 0.0212 0.0513 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.003 0.005
Echinococcus granulosus phosphoglycerate kinase 1 0.0174 0.0411 0.0411
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0036 0.0039 0.0145
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0031 0.0026 0.0342
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Trypanosoma brucei cytochrome P450, putative 0.0054 0.0086 0.1113
Trypanosoma cruzi metacaspase 5, putative 0.0048 0.0072 0.0935
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0093 0.0093
Onchocerca volvulus 0.0033 0.003 0.0083
Brugia malayi MH1 domain containing protein 0.0035 0.0035 0.0119
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0198 0.0474 0.1952
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0031 0.0026 0.0026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0047 0.007 0.007
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0019 0.0258
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0058 0.0195
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0011 0.0038
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0025 0.0011 0.0011
Brugia malayi RNA, U transporter 1 0.009 0.0183 0.0617
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.037
Echinococcus multilocularis neuropeptide receptor A26 0.1036 0.2726 0.2726
Echinococcus multilocularis Chromo domain 0.0024 0.0007 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0075 0.0075
Trypanosoma brucei trypanothione reductase 0.0105 0.0224 0.2895
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0014 0.0047
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0059 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0001 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0157 0.0364 0.1223
Onchocerca volvulus Putative transporter 0.0033 0.003 0.0083
Echinococcus granulosus multidrug resistance protein 1 0.0039 0.0048 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0284 0.0704 0.237
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0923 0.2422 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.006 0.0104 0.0104
Echinococcus multilocularis snurportin 1 0.0337 0.0848 0.0848
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0082 0.0155
Trypanosoma brucei glucose transporter, putative 0.0033 0.003 0.0382
Trichomonas vaginalis ABC transporter, putative 0.0057 0.0094 0.0179
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0036 0.0468
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0093 0.0349
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0105 0.0224 0.0919
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0066 0.0119 0.1541
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0203 0.0397
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Echinococcus multilocularis neuroglian 0.006 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.007 0.013 0.0438
Trypanosoma brucei sugar transporter, putative 0.0033 0.003 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0066 0.0119 0.1541
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0093 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0461 0.1182 0.1182
Loa Loa (eye worm) hypothetical protein 0.0156 0.0362 0.1219
Schistosoma mansoni glucose transport protein 0.0033 0.003 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0048 0.0072 0.0072
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0094 0.0194 0.0652
Loa Loa (eye worm) DnaJ domain-containing protein 0.0069 0.0128 0.0431
Echinococcus multilocularis musashi 0.0088 0.0178 0.0178
Schistosoma mansoni smad1 5 8 and 0.0035 0.0035 0.0035
Echinococcus granulosus apoptotic protease activating factor 1 0.0045 0.0063 0.0063
Mycobacterium ulcerans DNA polymerase IV 0.0212 0.0513 0.2114
Echinococcus multilocularis muscleblind protein 0.0153 0.0353 0.0353
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0056 0.0091 0.0265
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.004 0.0514
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.004 0.0514
Loa Loa (eye worm) hypothetical protein 0.0132 0.0298 0.1003
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1889 0.5018 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0513 0.6634
Loa Loa (eye worm) hypothetical protein 0.0167 0.039 0.1312
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0036 0.0144
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0048 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0033
Echinococcus granulosus neuropeptide s receptor 0.1036 0.2726 0.2726
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0203 0.0685
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0207 0.0207
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) hypothetical protein 0.0153 0.0353 0.1189
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0198 0.0474 0.0474
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0057 0.0094 0.0179
Loa Loa (eye worm) hypothetical protein 0.0032 0.0027 0.0091
Schistosoma mansoni transient receptor potential channel 0.0078 0.0151 0.0151
Brugia malayi jmjC domain containing protein 0.0074 0.0142 0.0478
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0775 0.2024 0.6812
Trichomonas vaginalis sugar transporter, putative 0.0033 0.003 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0136 0.0307 0.0603
Schistosoma mansoni lamin 0.0088 0.0178 0.0178
Toxoplasma gondii sugar transporter ST1 0.0033 0.003 0.0108
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0036 0.0144
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0033 0.003 0.0116
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0203 0.0685
Onchocerca volvulus 0.0033 0.003 0.0083
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0099
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0167 0.0325

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 0 % Paradoxical effect in Candida glabrata assessed as increase in turbidity at 64 times MIC ChEMBL. 17438060
Activity (functional) = 10 % Paradoxical effect in Candida krusei assessed as increase in turbidity at 64 times MIC ChEMBL. 17438060
Activity (functional) = 40 % Paradoxical effect in Candida tropicalis assessed as increase in turbidity at 64 times MIC ChEMBL. 17438060
Activity (functional) = 60 % Paradoxical effect in Candida albicans assessed as increase in turbidity at 64 times MIC ChEMBL. 17438060
Activity (functional) = 90 % Paradoxical effect in Candida parapsilosis assessed as increase in turbidity at 64 times MIC ChEMBL. 17438060
ED90 (functional) = 1.05 mg kg-1 Antifungal activity against Candida albicans 36082 infected BALB/c mouse assessed as fungal kidney burden after 14 days ChEMBL. 17420211
ED99 (functional) = 1.1 mg kg-1 Antifungal activity against Candida albicans 36082 infected BALB/c mouse assessed as fungal kidney burden after 14 days ChEMBL. 17420211
IC50 (binding) = 0.3 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 90028 ChEMBL. 17420211
IC50 (binding) = 0.3301 ng/ml Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose ChEMBL. 17420211
IC50 (binding) = 0.9 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 36082 ChEMBL. 17420211
IC50 (binding) = 1 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus MF5668 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 1.1 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus MF5668 ChEMBL. 17420211
IC50 (binding) = 1.3 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 1.325 ng/ml Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serum ChEMBL. 17420211
IC50 (binding) = 1.6 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus R21 ChEMBL. 17420211
IC50 (binding) = 2 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus ATCC 13073 ChEMBL. 17420211
IC50 (binding) = 2.077 ng/ml Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serum ChEMBL. 17420211
IC50 (binding) = 2.1 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 2.7 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus R21 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 2.8 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus ATCC 13073 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 2.8 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 3.2 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus MF5668 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 3.6 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus R21 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 4.8 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus MF5668 in presence of 50% human serum ChEMBL. 17420211
IC50 (binding) = 5.3 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 5.9 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus ATCC 13073 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 6.225 ng/ml Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serum ChEMBL. 17420211
IC50 (binding) = 6.3 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serum ChEMBL. 17420211
IC50 (binding) = 8.7 ng/ml Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 50% human serum ChEMBL. 17420211
IC50 (binding) = 9.4 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus ATCC 13073 in presence of 50% human serum ChEMBL. 17420211
IC50 (binding) = 10.3 ng/ml Inhibition of glucan synthase in Aspergillus fumigatus R21 in presence of 50% human serum ChEMBL. 17420211
IC50 (binding) = 14.7 ng/ml Inhibition of glucan synthase in Candida albicans SC5314 ChEMBL. 17420211
IC50 (binding) = 27 ng/ml Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serum ChEMBL. 17420211
IC50 (binding) = 36.9 ng/ml Inhibition of glucan synthase in Candida albicans SC5314 in presence of 20% human serum ChEMBL. 17420211
IC50 (binding) = 80.5 ng/ml Inhibition of glucan synthase in Candida albicans SC5314 in presence of 50% human serum ChEMBL. 17420211
MIC50 (functional) = 0.06 ug ml-1 Antifungal activity against Candida krusei after 48 hrs ChEMBL. 17438060
MIC50 (functional) = 0.125 ug ml-1 Antifungal activity against Candida albicans after 48 hrs ChEMBL. 17438060
MIC50 (functional) = 0.25 ug ml-1 Antifungal activity against Candida glabrata after 48 hrs ChEMBL. 17438060
MIC50 (functional) = 0.5 ug ml-1 Antifungal activity against Candida parapsilosis after 48 hrs ChEMBL. 17438060
MIC50 (functional) = 1 ug ml-1 Antifungal activity against Candida tropicalis after 48 hrs ChEMBL. 17438060
MIC90 (functional) = 0.25 ug ml-1 Antifungal activity against Candida albicans after 48 hrs ChEMBL. 17438060
MIC90 (functional) = 0.5 ug ml-1 Antifungal activity against Candida glabrata after 48 hrs ChEMBL. 17438060
MIC90 (functional) = 1 ug ml-1 Antifungal activity against Candida parapsilosis after 48 hrs ChEMBL. 17438060
MIC90 (functional) = 1 ug ml-1 Antifungal activity against Candida tropicalis after 48 hrs ChEMBL. 17438060
MIC90 (functional) = 1 ug ml-1 Antifungal activity against Candida krusei after 48 hrs ChEMBL. 17438060
Ratio (functional) = 2 Ratio of MIC for Candida albicans to MIC for Candida albicans in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 4 Ratio of MIC for Candida glabrata to MIC for Candida glabrata in presence of 50% mouse serum ChEMBL. 17420211
Ratio (functional) = 4 Ratio of MIC for Candida parapsilosis to MIC for Candida parapsilosis in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 4 Ratio of MIC for Candida tropicalis to MIC for Candida tropicalis in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 4 Ratio of MIC for Aspergillus flavus to MIC for Aspergillus terreus in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 8 Ratio of MIC for Candida krusei to MIC for Candida krusei in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 8 Ratio of MIC for Aspergillus flavus to MIC for Aspergillus flavus in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 8 Ratio of MIC for Aspergillus flavus to MIC for Aspergillus niger in presence of 50% human serum ChEMBL. 17420211
Ratio (functional) = 11 Ratio of MIC for Aspergillus fumigatus to MIC for Aspergillus fumigatus in presence of 50% human serum ChEMBL. 17420211

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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