Detailed information for compound 546359

Basic information

Technical information
  • TDR Targets ID: 546359
  • Name: 110540-41-5
  • MW: 389.345 | Formula: H12Mg3O12Si4
  • H donors: 2 H acceptors: 12 LogP: -5.57 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 2
  • SMILES: [O-][SiH](=O)[O-].[O-][SiH](=O)[O-].[O-][SiH](=O)O.[O-][SiH](=O)O.[MgH2+2].[MgH2+2].[MgH2+2]
  • InChi: 1S/3Mg.2HO3Si.2O3Si/c;;;4*1-4(2)3/h;;;2*1H;;/q3*+2;2*-1;2*-2
  • InChiKey: KNXVOGGZOFOROK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 11119-41-8
  • 12420-12-1
  • 14807-96-6
  • 37232-12-5
  • 99638-63-8
  • Agalite
  • Alpine talc USP, bc 127
  • Asbestine
  • B 13
  • B 13 (mineral)
  • B 9
  • Beaver White 200
  • CCRIS 3656
  • CI 77718
  • Cosmetic talc
  • CP 10-40
  • CP 38-33
  • Crystalite CRS 6002
  • Desertalc 57
  • Dimethyl Sulfoxide
  • EINECS 238-877-9
  • Emtal 500
  • Emtal 549
  • Emtal 596
  • Emtal 599
  • EX-IT
  • Fibrene C 400
  • Finntalc C10
  • Finntalc M05
  • Finntalc M15
  • Finntalc P40
  • Finntalc PF
  • French chalk
  • FW-XO
  • HSDB 830
  • IT Extra
  • LMR 100
  • Lo Micron talc USP, bc 2755
  • LS-2116
  • Magnesium silicate talc
  • Magnesium silicate, hydrous
  • Micro Ace K1
  • Micro Ace L1
  • Micron White 5000A
  • Micron White 5000P
  • Micron White 5000S
  • Microtalco IT Extra
  • Mistron 139
  • Mistron 2SC
  • Mistron frost P
  • Mistron RCS
  • Mistron Star
  • Mistron super frost
  • Mistron vapor
  • MP 12-50
  • MP 25-38
  • MP 40-27
  • MP 45-26
  • Mussolinite
  • NCI-C06008
  • Nonasbestiform talc
  • Nonfibrous talc
  • Nytal 200
  • Nytal 400
  • P 3
  • P 3 (Mineral)
  • PK-C
  • PK-N
  • Polytal 4641
  • Polytal 4725
  • Silicates (<1% quartz):talc (not containing asbestos)
  • Silicates: talc (containing no asbestos)
  • Snowgoose
  • Soapstone
  • steatite
  • Steatite talc
  • Steawhite
  • Supreme
  • Supreme dense
  • Talc
  • Talc (containing no asbestos)
  • Talc (Mg3H2(SiO3)4)
  • Talc (powder)
  • Talc (powder), containing no asbestos fibers
  • Talc [JAN]
  • Talc, containing no asbestos fibers
  • Talc, non-asbestos form
  • Talc, not containing asbestiform fibers
  • Talcan PK-P
  • Talcron CP 44-31
  • Talcum
  • trimagnesium; dioxido(oxo)silane; hydroxy-oxido-oxo-silane
  • trimagnesium; dioxido(oxo)silane; hydroxy-oxido-oxosilane
  • trimagnesium; bis(oxidanidyl)-oxo-silane; hydroxy-oxidanidyl-oxo-silane
  • trimagnesium; hydroxy-keto-oxido-silane; keto(dioxido)silane
  • trimagnesium; dioxido-oxosilane; hydroxy-oxido-oxosilane
  • trimagnesium; dioxido-oxo-silane; hydroxy-oxido-oxo-silane
  • trimagnesium; hydroxy-keto-oxido-silane; keto-dioxido-silane
  • TY 80

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0136 0.0112 0.0111
Echinococcus granulosus snurportin 1 0.0615 0.0637 0.0637
Mycobacterium leprae Probable lipase LipE 0.0365 0.0363 0.7728
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0193 0.0174 0.6089
Brugia malayi beta-lactamase family protein 0.0365 0.0363 0.0363
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.001 0.001
Schistosoma mansoni hypothetical protein 0.3427 0.3726 0.3726
Onchocerca volvulus 0.0167 0.0146 0.0778
Trypanosoma brucei unspecified product 0.0059 0.0027 0.0271
Leishmania major glycerol uptake protein, putative 0.0788 0.0827 0.8407
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0049 0.0016 0.0016
Schistosoma mansoni microtubule-associated protein tau 0.2079 0.2245 0.2245
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0136 0.0136
Trypanosoma brucei cytochrome P450, putative 0.0059 0.0027 0.027
Trichomonas vaginalis rotamase, putative 0.0036 0.0002 0.0009
Schistosoma mansoni alpha-glucosidase 0.0136 0.0112 0.0112
Loa Loa (eye worm) pax transcription factor protein 2 0.0547 0.0563 0.0563
Onchocerca volvulus 0.0164 0.0142 0.0759
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0149 0.0126 0.2482
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Leishmania major phosphopantetheinyl transferase-like protein 0.0046 0.0013 0.0128
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.9141 1 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0246 0.0232 0.0232
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0065 0.0034 0.0596
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0072 0.0041 0.0041
Toxoplasma gondii heat shock protein HSP90 0.0035 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0044 0.001 0.001
Brugia malayi jmjC domain containing protein 0.0064 0.0032 0.0032
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0044 0.001 0.0101
Mycobacterium tuberculosis Probable hydrolase 0.0365 0.0363 0.1429
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0006 0.0082
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0007 0.0038
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0386 0.0386 0.0386
Trichomonas vaginalis heat shock protein, putative 0.0035 0 0.0001
Echinococcus multilocularis RUN 0.0064 0.0032 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0126 0.0126
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2331 0.2522 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Loa Loa (eye worm) hypothetical protein 0.0164 0.0142 0.0142
Onchocerca volvulus Huntingtin homolog 0.0649 0.0675 0.3681
Echinococcus granulosus nAChR subunit 0.0072 0.0041 0.0041
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0136 0.0136
Plasmodium vivax heat shock protein 86, putative 0.0035 0 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0027 0.0271
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0027 0.0146
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0136 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0099 0.0071 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0044 0.001 0.001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0136 0.0112 0.0112
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0042 0.0042
Echinococcus granulosus GPCR family 2 0.0099 0.0071 0.0071
Loa Loa (eye worm) cytochrome P450 0.004 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0067
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0085 0.0056 0.0056
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0193 0.0174 0.1765
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0072 0.0041 0.0041
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Trichomonas vaginalis esterase, putative 0.0365 0.0363 0.1984
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0044 0.001 0.0157
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0072 0.0041 0.0041
Mycobacterium leprae conserved hypothetical protein 0.0046 0.0013 0.0137
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0262 0.0249 0.1364
Echinococcus multilocularis tar DNA binding protein 0.0062 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0127 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0112 0.0111
Schistosoma mansoni hypothetical protein 0.0887 0.0936 0.0936
Schistosoma mansoni alpha-glucosidase 0.0136 0.0112 0.0112
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Schistosoma mansoni kinase 0.015 0.0127 0.0127
Schistosoma mansoni Smad4 0.005 0.0017 0.0017
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0135 0.011 0.06
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0136 0.0112 0.0111
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0027 0.0271
Trypanosoma brucei unspecified product 0.0041 0.0007 0.0067
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0046 0.0013 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0123 0.067
Brugia malayi hypothetical protein 0.0127 0.0102 0.0101
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.001 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0044 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0064 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0171 0.0933
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0065 0.0034 0.0124
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0147 0.0124 0.0124
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0072 0.0041 0.0041
Onchocerca volvulus 0.0189 0.017 0.091
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0001 0.0007
Leishmania major basic transcription factor 3a, putative 0.0035 0.0001 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0092 0.1862
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0009 0.0008
Brugia malayi Bromodomain containing protein 0.004 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0111 0.0085 0.0085
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Plasmodium vivax ornithine aminotransferase, putative 0.0065 0.0034 0.0408
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0025 0.0025
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0033 0.0032
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0788 0.0827 0.0827
Echinococcus multilocularis ubiquitin specific protease 41 0.0193 0.0174 0.0174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0136 0.0112 0.0112
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0018 0.0212
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0092 0.0356
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0193 0.0174 0.0174
Loa Loa (eye worm) nuclear receptor NHR-67 0.0064 0.0033 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0078 0.0298
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus granulosus survival motor neuron protein 1 0.0941 0.0996 0.0996
Echinococcus multilocularis Niemann Pick C1 protein 0.0207 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Onchocerca volvulus 0.0072 0.0041 0.0205
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0079 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0037 0.0201
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0062 0.003 0.003
Trichomonas vaginalis porcupine, putative 0.0788 0.0827 0.4525
Entamoeba histolytica vacuolar protein sorting 26 0.0788 0.0827 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0365 0.0363 0.1429
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0006 0.0082
Plasmodium vivax acyl-CoA synthetase, putative 0.0111 0.0085 0.102
Trypanosoma brucei PAB1-binding protein , putative 0.0127 0.0102 0.1032
Echinococcus multilocularis lamin dm0 0.0081 0.0051 0.005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0193 0.0174 0.095
Trypanosoma cruzi GUP1, putative 0.0788 0.0827 0.8407
Loa Loa (eye worm) latrophilin receptor protein 2 0.0099 0.0071 0.0071
Loa Loa (eye worm) GABA receptor subunit 0.0039 0.0005 0.0005
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0039 0.0005 0.0005
Onchocerca volvulus 0.0064 0.0032 0.0153
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Entamoeba histolytica Ran family GTPase 0.0042 0.0009 0.01
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0147 0.0124 0.0124
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0365 0.0363 0.1429
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0144 0.012 0.012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0032 0.0032
Brugia malayi intermediate filament protein 0.0081 0.0051 0.005
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0065 0.0034 0.0634
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0513 0.0526 0.0526
Plasmodium vivax importin-beta 2, putative 0.0058 0.0025 0.0304
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0008 0.0283
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0365 0.0363 0.3686
Brugia malayi MH2 domain containing protein 0.005 0.0017 0.0017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0027 0.0271
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0002 0.0022
Brugia malayi hypothetical protein 0.0064 0.0033 0.0032
Onchocerca volvulus Serine\/threonine kinase homolog 0.0294 0.0285 0.1543
Loa Loa (eye worm) ACC-1 protein 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0044 0.001 0.003
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0009 0.0008
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0788 0.0827 1
Loa Loa (eye worm) MBOAT family protein 0.9141 1 1
Brugia malayi hypothetical protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) Smad1 0.005 0.0017 0.0017
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0006 0.0015
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0002 0.0022
Brugia malayi jmjC domain containing protein 0.0102 0.0075 0.0074
Plasmodium vivax SET domain protein, putative 0.0221 0.0205 0.248
Schistosoma mansoni ran 0.0042 0.0009 0.0009
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.001 0.0081
Loa Loa (eye worm) hypothetical protein 0.0788 0.0827 0.0827
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0072 0.0041 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0032 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0007 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0035 0 0.0000041849
Loa Loa (eye worm) hhat protein 0.0788 0.0827 0.0827
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0064 0.0033 0.0032
Loa Loa (eye worm) glutaminase 0.0284 0.0274 0.0274
Brugia malayi Pax transcription factor protein 2 0.0547 0.0563 0.0563
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0112 0.0111
Echinococcus granulosus dna polymerase kappa 0.0059 0.0027 0.0027
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Schistosoma mansoni chromobox protein 0.0068 0.0037 0.0037
Echinococcus granulosus ecdysone induced protein 78C 0.0136 0.0112 0.0111
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.046 0.0468 0.2557
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0193 0.0174 0.0174
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0017 0.0017
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0331 0.0325 0.0325
Mycobacterium tuberculosis Conserved protein 0.0365 0.0363 0.1429
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0005 0.0005
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0225 0.0209 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0788 0.0827 0.4525
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0062
Leishmania major hypothetical protein, conserved 0.0037 0.0003 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0033 0.0032
Echinococcus granulosus Smad4 0.005 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0294 0.0285 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Schistosoma mansoni hypothetical protein 0.0192 0.0173 0.0173
Echinococcus multilocularis muscleblind protein 1 0.2155 0.2328 0.2328
Loa Loa (eye worm) acetyltransferase 0.0161 0.0139 0.0139
Entamoeba histolytica deoxycytidyl transferase, putative 0.0059 0.0027 0.0321
Echinococcus granulosus intermediate filament protein 0.0081 0.0051 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0006 0.0082
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0294 0.0285 0.0285
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Onchocerca volvulus 0.1699 0.1828 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0788 0.0827 1
Loa Loa (eye worm) hypothetical protein 0.0214 0.0197 0.0197
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Onchocerca volvulus 0.0072 0.0041 0.0205
Leishmania major cytochrome p450-like protein 0.004 0.0006 0.0064
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0149 0.0126 0.2482
Loa Loa (eye worm) hypothetical protein 0.2155 0.2328 0.2328
Leishmania major glycerol uptake protein, putative 0.0788 0.0827 0.8407
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0005 0.0005
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0016 0.0016
Trichomonas vaginalis helicase, putative 0.0087 0.0058 0.0317
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0044 0.001 0.0157
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0027 0.0027
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0016 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0003
Entamoeba histolytica hypothetical protein, conserved 0.0788 0.0827 1
Echinococcus multilocularis chromobox protein 1 0.0068 0.0037 0.0037
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0072 0.0041 0.0041
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0313 0.0306 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0788 0.0827 0.4525
Mycobacterium ulcerans putative regulatory protein 0.009 0.0061 0.1175
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Trichomonas vaginalis glutaminase, putative 0.0284 0.0274 0.1497
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Echinococcus multilocularis glycine receptor subunit beta 0.0072 0.0041 0.0041
Leishmania major DNA polymerase eta, putative 0.0059 0.0027 0.0271
Mycobacterium tuberculosis Probable lipase LipD 0.0365 0.0363 0.1429
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.003 0.003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0027 0.0096
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0044 0.001 0.0157
Schistosoma mansoni smad1 5 8 and 0.005 0.0017 0.0017
Loa Loa (eye worm) inositol-1 0.0037 0.0002 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0331 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0185 0.0165 0.0165
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0017 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0125 0.0099 0.0541
Schistosoma mansoni SET domain protein 0.0042 0.0008 0.0008
Brugia malayi nuclear receptor RXR 0.0064 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0046 0.0013 0.0152
Loa Loa (eye worm) hypothetical protein 0.0064 0.0032 0.0032
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0044 0.001 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0027 0.0271
Entamoeba histolytica hypothetical protein 0.0035 0.0001 0.0005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0005 0.0005
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Trypanosoma brucei glycerol uptake protein, putative 0.0788 0.0827 0.8407
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.0249 0.1364
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0044 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Brugia malayi F/Y-rich N-terminus family protein 0.014 0.0116 0.0115
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0207 0.0189 0.2281
Loa Loa (eye worm) hypothetical protein 0.0189 0.017 0.017
Loa Loa (eye worm) cytochrome P450 family protein 0.0159 0.0136 0.0136
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0032 0.0032
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0032 0.0032
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0044 0.001 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0365 0.0363 0.1984
Echinococcus multilocularis muscleblind protein 0.2155 0.2328 0.2328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0513 0.0526 0.0526
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0 0.0005
Schistosoma mansoni bromodomain containing protein 0.0155 0.0132 0.0132
Onchocerca volvulus 0.0042 0.0008 0.0024
Leishmania major GTP-binding protein, putative 0.0042 0.0009 0.0085
Schistosoma mansoni cytochrome P450 0.004 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0006 0.0015
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0072 0.0041 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0112 0.0111
Onchocerca volvulus 0.0072 0.0041 0.0205
Brugia malayi MBOAT family protein 0.9141 1 1
Mycobacterium tuberculosis Probable reductase 0.0107 0.0079 0.0304
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0099 0.0071 0.0071
Onchocerca volvulus 0.0365 0.0363 0.1967
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0136 0.0112 0.0111
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0193 0.0174 0.0174
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0331 0.0325 0.0325
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0003 0.0003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0365 0.0363 0.0363
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0001 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0006 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Entamoeba histolytica hypothetical protein 0.0472 0.0481 0.5811
Brugia malayi CXXC zinc finger family protein 0.0386 0.0386 0.0386
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.093 0.0984 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0079 0.0803
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0092 0.0356
Onchocerca volvulus 0.0044 0.001 0.0034
Schistosoma mansoni niemann-pick C1 (NPC1) 0.021 0.0192 0.0192
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0788 0.0827 0.0827
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0006 0.0015
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0065 0.0034 0.0596
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0788 0.0827 1
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.001 0.003
Brugia malayi N-terminal motif family protein 0.0185 0.0165 0.0165
Echinococcus granulosus fetal alzheimer antigen falz 0.0068 0.0037 0.0036
Brugia malayi MH1 domain containing protein 0.005 0.0017 0.0017
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0044 0.001 0.0157
Brugia malayi hypothetical protein 0.0082 0.0052 0.0052
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0065 0.0034 0.0408
Loa Loa (eye worm) hypothetical protein 0.0037 0.0003 0.0003
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0788 0.0827 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.003 0.003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus multilocularis expressed conserved protein 0.0194 0.0175 0.0175
Echinococcus granulosus beta LACTamase domain containing family member 0.0365 0.0363 0.0363
Onchocerca volvulus 0.0064 0.0032 0.0153
Loa Loa (eye worm) hypothetical protein 0.0111 0.0085 0.0085
Trypanosoma cruzi polo-like protein kinase, putative 0.0294 0.0285 0.2899
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0013 0.0013
Onchocerca volvulus 0.0049 0.0016 0.0065
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0 0.0001
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Schistosoma mansoni patched 1 0.0089 0.0059 0.0059
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Plasmodium vivax glutathione reductase, putative 0.0047 0.0013 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Schistosoma mansoni DNA polymerase eta 0.0059 0.0027 0.0027
Brugia malayi Smad1 0.005 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0044 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0123 0.067
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0001 0.0003
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0013 0.0152
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0112 0.0111
Brugia malayi nuclear hormone receptor 0.0064 0.0033 0.0032
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0032 0.0032
Brugia malayi MH1 domain containing protein 0.005 0.0017 0.0017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0149 0.0126 0.2482
Schistosoma mansoni lipoxygenase 0.0246 0.0232 0.0232
Echinococcus granulosus nAChR subunit 0.0039 0.0005 0.0005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0009 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Echinococcus granulosus Aminotransferase class III 0.0065 0.0034 0.0034
Echinococcus multilocularis dna polymerase eta 0.0059 0.0027 0.0027
Schistosoma mansoni transcription factor btf3 0.0035 0.0001 0.0001
Schistosoma mansoni lamin 0.0081 0.0051 0.0051
Brugia malayi hypothetical protein 0.0064 0.0033 0.0032
Echinococcus granulosus expressed conserved protein 0.0194 0.0175 0.0175
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0013 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0136 0.0112 0.0112
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0006 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0033 0.0032
Trichomonas vaginalis hypothetical protein 0.0047 0.0014 0.0073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Mycobacterium ulcerans L-lysine aminotransferase 0.0065 0.0034 0.0634
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0136 0.0112 0.0111
Leishmania major glycerol uptake protein, putative 0.0788 0.0827 0.8407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0027 0.0146
Trypanosoma brucei ISWI complex protein 0.0041 0.0007 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0031 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0113 0.0086 0.0086
Onchocerca volvulus 0.0386 0.0386 0.2094
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0006 0.0082
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0051 0.0051
Mycobacterium ulcerans aldehyde dehydrogenase 0.0432 0.0437 0.8723
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.001 0.0101
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.044 0.0446 0.4528
Toxoplasma gondii hypothetical protein 0.0788 0.0827 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.044 0.0446 0.4528
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0007 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0062 0.003 0.003
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0006 0.0015
Schistosoma mansoni acetyl-CoA synthetase 0.0044 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0513 0.0526 0.0526
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0513 0.0526 0.0526
Brugia malayi mbt repeat family protein 0.0049 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0136 0.0112 0.0111
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0009 0.0102
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Loa Loa (eye worm) glutathione reductase 0.0047 0.0013 0.0013
Loa Loa (eye worm) steroid hormone receptor 0.0136 0.0112 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0104 0.0076 0.0076
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0111 0.0085 0.165
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0027 0.0322
Echinococcus granulosus glycine receptor subunit beta 0.0072 0.0041 0.0041
Echinococcus granulosus chromobox protein 1 0.0068 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0313 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0207 0.0189 0.0189
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0059 0.0027 0.049
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0006 0.0082
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0003 0.0003
Echinococcus multilocularis nAChR subunit 0.0039 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0111 0.0085 0.0085
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.0139 0.0139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0313 0.0306 0.0306
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0072 0.0041 0.0041
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0136 0.0112 0.0112
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0006 0.0076
Brugia malayi Pre-SET motif family protein 0.1494 0.1602 0.1602
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0016 0.0016
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0072 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0058 0.0025 0.0025
Schistosoma mansoni eyes absent homolog 0.0091 0.0062 0.0062
Echinococcus granulosus glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Toxoplasma gondii hypothetical protein 0.019 0.0171 0.2061
Onchocerca volvulus 0.0136 0.0112 0.0589
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0013 0.0134
Onchocerca volvulus 0.0081 0.0051 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0365 0.0363 0.0363
Leishmania major cathepsin L-like protease 0.0071 0.004 0.0402
Loa Loa (eye worm) MBCTL1 0.0056 0.0023 0.0023
Trypanosoma brucei heat shock protein 90, putative 0.0035 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0174 0.095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0126 0.1519
Leishmania major hypothetical protein, conserved 0.0365 0.0363 0.3686
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0432 0.0437 0.8723
Onchocerca volvulus 0.0039 0.0005 0.0004
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0085 0.0056 0.0056
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0072 0.0041 0.0041
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0027 0.0027
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0023 0.0023
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0009 0.0295
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Echinococcus multilocularis neuropeptide s receptor 0.0501 0.0513 0.0512
Leishmania major cytochrome p450-like protein 0.004 0.0006 0.0064
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0001 0.0006
Brugia malayi Importin beta-1 subunit 0.0058 0.0025 0.0025
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0017 0.0017
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0006 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Onchocerca volvulus 0.0365 0.0363 0.1967
Brugia malayi MBOAT family protein 0.0788 0.0827 0.0827
Onchocerca volvulus 0.0189 0.017 0.091
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0033 0.0032
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0009 0.0085
Echinococcus granulosus mixed lineage leukemia protein mll 0.0104 0.0076 0.0076
Onchocerca volvulus 0.0064 0.0033 0.0156
Onchocerca volvulus 0.0044 0.001 0.0034
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0193 0.0174 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0006 0.0015
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Schistosoma mansoni ap endonuclease 0.0059 0.0027 0.0027
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0111 0.0085 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0058 0.0026 0.014
Brugia malayi Heterochromatin protein 1 0.0068 0.0037 0.0037
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0032 0.0383
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0189 0.017 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Echinococcus granulosus ubiquitin specific protease 41 0.0193 0.0174 0.0174
Schistosoma mansoni nuclear hormone receptor 0.0136 0.0112 0.0112
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0135 0.011 0.1116
Echinococcus multilocularis survival motor neuron protein 1 0.0941 0.0996 0.0996
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0164 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0788 0.0827 0.0827
Brugia malayi beta-lactamase 0.0365 0.0363 0.0363
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0513 0.0526 0.0526
Onchocerca volvulus 0.0788 0.0827 0.4513
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1494 0.1602 0.1602
Echinococcus granulosus muscleblind protein 0.2155 0.2328 0.2328
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0001 0.0001
Onchocerca volvulus 0.0044 0.001 0.0034
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0788 0.0827 0.0827
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Echinococcus multilocularis microtubule associated protein 2 0.2079 0.2245 0.2245
Loa Loa (eye worm) hypothetical protein 0.0149 0.0126 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0018 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.001 0.0157
Onchocerca volvulus 0.0092 0.0063 0.0322
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0044 0.001 0.0157
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0127 0.0102 0.0102
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0136 0.0112 0.0112
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.046 0.0468 0.9344
Schistosoma mansoni glutaminase 0.0284 0.0274 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0171 0.0933
Schistosoma mansoni hypothetical protein 0.0099 0.0071 0.0071
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0035 0 0.0000041849
Loa Loa (eye worm) MH2 domain-containing protein 0.074 0.0775 0.0775
Echinococcus granulosus thyroid hormone receptor alpha 0.0064 0.0033 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0136 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.004 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0193 0.0174 0.1765
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0032 0.0383
Toxoplasma gondii thioredoxin reductase 0.0047 0.0013 0.016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0044 0.001 0.0101
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.046 0.0468 0.1845
Schistosoma mansoni hypothetical protein 0.0887 0.0936 0.0936
Loa Loa (eye worm) hypothetical protein 0.0156 0.0133 0.0133
Brugia malayi excitatory GABA receptor EXP-1A 0.0072 0.0041 0.0041
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0079 0.2771
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0044 0.001 0.003
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0006 0.0015
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0072 0.0041 0.0041
Schistosoma mansoni loxhd1 0.0064 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0067
Onchocerca volvulus 0.0365 0.0363 0.1967
Brugia malayi RNA, U transporter 1 0.0164 0.0142 0.0142
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0365 0.0363 0.0363
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0788 0.0827 0.0827
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0035 0 0.0000041849
Brugia malayi Cytochrome P450 family protein 0.0059 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0007 0.0035
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0039 0.0005 0.0005
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0134 0.0109 0.0423
Trypanosoma brucei heat shock protein 90, putative 0.0035 0 0.0001
Echinococcus granulosus dnaJ subfamily B 0.3427 0.3726 0.3725
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0 0.0001
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0788 0.0827 0.0827
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0788 0.0827 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0153 0.0836
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0006 0.0082
Onchocerca volvulus 0.0081 0.0051 0.0255
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0221 0.0205 0.0205
Toxoplasma gondii exonuclease III APE 0.0059 0.0027 0.0322
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0126 0.2482
Leishmania major DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0189 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0099 0.0071 0.0071
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0001 0.0001
Echinococcus granulosus o acyltransferase membrane bound domain 0.0788 0.0827 0.0827
Loa Loa (eye worm) hypothetical protein 0.0189 0.017 0.017
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0004 0.0003
Echinococcus multilocularis zinc finger protein 0.0066 0.0034 0.0034
Toxoplasma gondii hypothetical protein 0.015 0.0127 0.1532
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0059 0.0027 0.0027
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0035 0 0.0000041849
Echinococcus multilocularis neuropeptide receptor A26 0.0501 0.0513 0.0512
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0365 0.0363 0.7239
Schistosoma mansoni terminal deoxycytidyl transferase 0.0059 0.0027 0.0027
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.9141 1 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0064 0.0033 0.0032
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0046 0.0013 0.0209
Brugia malayi Doublecortin family protein 0.0064 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0788 0.0827 0.0827
Loa Loa (eye worm) hypothetical protein 0.0056 0.0023 0.0023
Loa Loa (eye worm) DR-78 0.0064 0.0033 0.0033
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0002 0.0017
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0027 0.0173
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4139 0.4507 0.4507
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0171 0.0933
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0018 0.0096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0125 0.0099 0.0541
Echinococcus granulosus glycine receptor subunit beta 0.0072 0.0041 0.0041
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.001 0.0101
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0006 0.0015
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0001 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0059 0.0027 0.0096
Schistosoma mansoni smad 0.005 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0136 0.0112 0.0111
Echinococcus multilocularis nAChR subunit 0.0072 0.0041 0.0041
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.001 0.0055
Plasmodium falciparum heat shock protein 90 0.0035 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus zinc finger protein 0.0066 0.0034 0.0034
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0033 0.0032
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0016 0.0016
Onchocerca volvulus 0.0233 0.0218 0.1171
Brugia malayi Latrophilin receptor protein 2 0.0099 0.0071 0.0071
Brugia malayi Cation transporter family protein 0.0189 0.017 0.017
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0208 0.0191 0.0191
Entamoeba histolytica hypothetical protein 0.0472 0.0481 0.5811
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0205 0.0187 0.0187
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0079 0.0304
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0009 0.0085
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0788 0.0827 0.0827
Schistosoma mansoni hypothetical protein 0.0057 0.0025 0.0025
Brugia malayi glutathione reductase 0.0047 0.0013 0.0013
Brugia malayi Pre-SET motif family protein 0.0221 0.0205 0.0205
Echinococcus multilocularis geminin 0.0887 0.0936 0.0936
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0104 0.0076 0.0076
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0008 0.0098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0033 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0013 0.0072
Brugia malayi cytochrome P450 0.004 0.0006 0.0006
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0788 0.0827 0.0827
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0065 0.0034 1
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0027 0.0146
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0059 0.0027 0.0027
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0432 0.0437 0.1722
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0078 0.0298
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0002 0.0012
Schistosoma mansoni alpha glucosidase 0.0035 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.0365 0.0363 0.0363
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0002 0.0002
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0013 0.0152
Echinococcus granulosus dna polymerase eta 0.0059 0.0027 0.0027
Brugia malayi Bromodomain containing protein 0.0178 0.0158 0.0158
Loa Loa (eye worm) histone methyltransferase 0.0127 0.0102 0.0102
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0006 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus Niemann Pick C1 protein 0.0207 0.0189 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0001 0.0003
Schistosoma mansoni zinc finger protein 0.0064 0.0033 0.0033
Leishmania major hypothetical protein, conserved 0.0788 0.0827 0.8407
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0365 0.0363 0.7239
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0064 0.0033 0.0033
Echinococcus granulosus chromobox protein 1 0.0068 0.0037 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0365 0.0363 0.4385
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0059 0.0324
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0035 0 0.0000041849
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0262 0.0249 0.1364
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Brugia malayi mbt repeat family protein 0.0049 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0078 0.0048 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0136 0.0112 0.0111
Loa Loa (eye worm) nuclear hormone receptor 0.0064 0.0033 0.0033
Echinococcus granulosus smad 0.005 0.0017 0.0017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0099 0.0071 0.0071
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0136 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.005 0.0017 0.0017
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0044 0.001 0.003
Schistosoma mansoni smad1 5 8 and 0.005 0.0017 0.0017
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0064 0.0033 0.0033
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0027 0.0492
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0017 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0136 0.0112 0.0112
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0044 0.001 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0072 0.0041 0.0041
Loa Loa (eye worm) ACC-1 protein 0.0072 0.0041 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0102 0.1032
Toxoplasma gondii LsmAD domain-containing protein 0.0127 0.0102 0.1227
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Brugia malayi ecdysone receptor 0.0064 0.0033 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0136 0.0112 0.0111
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Mycobacterium ulcerans hypothetical protein 0.046 0.0468 0.9344
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0126 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0006 0.0015
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0044 0.001 0.0081
Brugia malayi hypothetical protein 0.0472 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.0472 0.0481 0.0481
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0006 0.0015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0013 0.0072
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0006 0.0082
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0001 0.0006
Schistosoma mansoni steroid hormone receptor ad4bp 0.0136 0.0112 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0149 0.0126 0.0489
Entamoeba histolytica hypothetical protein 0.0039 0.0005 0.0054
Echinococcus multilocularis snurportin 1 0.0615 0.0637 0.0637
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0039 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0061 0.0332
Echinococcus granulosus geminin 0.0887 0.0936 0.0936
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0513 0.0526 0.0526
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0044 0.001 0.0157
Brugia malayi CHD4 protein 0.0037 0.0003 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0126 0.1278
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0051 0.005
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0037 0.0003 0.0025
Schistosoma mansoni nuclear receptor 0.0064 0.0033 0.0033
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0143 0.0763
Loa Loa (eye worm) MBOAT family protein 0.0788 0.0827 0.0827
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0065 0.0034 0.0124
Echinococcus granulosus nuclear receptor nhr 48 0.0064 0.0033 0.0032
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0788 0.0827 0.0827
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0051 0.0051
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0065 0.0034 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0006 0.0015
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0035 0 0.0000041849
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0002 0.0016
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0006 0.0064
Brugia malayi hypothetical protein 0.0064 0.0032 0.0032
Trichomonas vaginalis rotamase, putative 0.0037 0.0003 0.0014
Echinococcus multilocularis cpg binding protein 0.0412 0.0414 0.0414
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0001 0.0005
Brugia malayi nuclear receptor NHR-88 0.0064 0.0033 0.0032
Schistosoma mansoni hypothetical protein 0.0099 0.0071 0.0071
Loa Loa (eye worm) glutaminase 2 0.0284 0.0274 0.0274
Echinococcus granulosus transcription factor btf3 0.0035 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0214 0.0197 0.0197
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0017 0.0017
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0136 0.0136
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0002 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0112 0.0111
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0225 0.0209 0.1141
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0033 0.0033
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0033 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0004 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0033 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0432 0.0437 0.4437
Mycobacterium ulcerans aldehyde dehydrogenase 0.0432 0.0437 0.8723
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0003 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0136 0.0112 0.0112
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0079 0.0079
Brugia malayi diacylglycerol acyltransferase 0.0788 0.0827 0.0827
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0065 0.0034 0.0634
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0102 0.1227
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.046 0.0468 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0041 0.0041
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0009 0.0102
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0023 0.0023
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0 0.0001
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0164 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0136 0.0112 0.0111
Plasmodium vivax endoplasmin, putative 0.0035 0 0.0002
Brugia malayi TAR-binding protein 0.0062 0.003 0.003
Echinococcus multilocularis sterol O acyltransferase 1 0.0788 0.0827 0.0827
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Conserved protein 0.0365 0.0363 0.1429
Schistosoma mansoni polycystin 1-related 0.0064 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Brugia malayi SET domain containing protein 0.0042 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0006 0.0015
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0258 0.0245 0.0245
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0258 0.0245 0.0245
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0072 0.0041 0.0041
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0189 0.017 0.017
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0016 0.0016
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0136 0.0112 0.0112
Schistosoma mansoni transcription factor LCR-F1 0.0472 0.0481 0.0481
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0027 0.0322
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0064 0.0033 0.0032
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0136 0.0112 0.0111
Onchocerca volvulus Putative nachr subunit 0.0189 0.017 0.091
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus granulosus Niemann Pick C1 protein 0.0295 0.0286 0.0286
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Trypanosoma brucei glycerol uptake protein, putative 0.0788 0.0827 0.8407
Mycobacterium ulcerans lipase LipD 0.0365 0.0363 0.7239
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0079 0.0432
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0009 0.0009
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0294 0.0285 0.2899
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0131 0.0106 0.1073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0013 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0112 0.0111
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0013 0.0134
Onchocerca volvulus 0.0064 0.0033 0.0156
Onchocerca volvulus 0.0192 0.0173 0.0926
Brugia malayi hypothetical protein 0.0167 0.0146 0.0146
Trypanosoma cruzi ISWI complex protein 0.0041 0.0007 0.0065
Onchocerca volvulus 0.005 0.0017 0.007
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0102 0.1032
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0019 0.0102
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0002 0.0026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0027 0.0491
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0136 0.0112 0.0112
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0025 0.0255
Loa Loa (eye worm) hypothetical protein 0.0109 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Brugia malayi MH2 domain containing protein 0.005 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0006 0.0082
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0044 0.001 0.0121
Echinococcus granulosus ornithine aminotransferase 0.0065 0.0034 0.0034
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0027 0.0271
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.004 0.0402
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0126 0.2482
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0059 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0079 0.0432
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0072 0.0041 0.0041
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0072 0.0041 0.0041
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0044 0.001 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0285 0.0285
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0078 0.0298
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0037 0.0003 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0044 0.001 0.003
Brugia malayi nuclear hormone receptor family member odr-7 0.0064 0.0033 0.0032
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0189 0.017 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0365 0.0363 0.1429
Brugia malayi steroid hormone receptor 0.0136 0.0112 0.0111
Echinococcus multilocularis ornithine aminotransferase 0.0065 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0208 0.0191 0.0191
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0068 0.0037 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0472 0.0481 0.0481
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.2155 0.2328 0.2328
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0006 0.0082
Onchocerca volvulus 0.0044 0.001 0.0034
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0002 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0472 0.0481 0.0481
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0006 0.0082
Brugia malayi follicle stimulating hormone receptor 0.121 0.129 0.129
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0099 0.0071 0.0071
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0016 0.0016
Schistosoma mansoni rab6-interacting 0.0064 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0131 0.0106 0.1073
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0097 0.0069 0.0262
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0059 0.0059
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0193 0.0174 0.1765
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0112 0.0111
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0068 0.0037 0.0036
Brugia malayi beta-NAC-like protein 0.0035 0.0001 0.0001
Echinococcus multilocularis chromobox protein 1 0.0068 0.0037 0.0037
Schistosoma mansoni coup transcription factor 0.0136 0.0112 0.0112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0072 0.0041 0.0041
Mycobacterium leprae conserved hypothetical protein 0.009 0.0061 0.1181
Loa Loa (eye worm) hypothetical protein 0.0044 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0193 0.0174 0.0174
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0111 0.0085 0.0325
Loa Loa (eye worm) hypothetical protein 0.0111 0.0085 0.0085
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0027 0.0321
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0827 0.087 0.087
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0027 0.0492
Echinococcus granulosus L aminoadipate semialdehyde 0.0164 0.0142 0.0142
Brugia malayi Cation transporter family protein 0.0072 0.0041 0.0041
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.0025 0.0025
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0001 0.0007
Schistosoma mansoni importin beta-1 0.0058 0.0025 0.0025
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0038 0.0004 0.0003
Schistosoma mansoni rab6-interacting 0.0064 0.0032 0.0032
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Giardia lamblia Kinase, PLK 0.0294 0.0285 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Schistosoma mansoni aldehyde dehydrogenase 0.0432 0.0437 0.0437
Echinococcus granulosus tumor protein p63 0.034 0.0336 0.0336
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0079 0.0803
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0041 0.0041
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0033 0.0156
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0062 0.003 0.003
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0002 0.0025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0027 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Brugia malayi Cation transporter family protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0027 0.0027
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0064 0.0033 0.0033
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0079 0.0079
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0112 0.0112
Echinococcus multilocularis tumor protein p63 0.034 0.0336 0.0336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Plasmodium vivax hypothetical protein, conserved 0.009 0.0061 0.0734
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0065 0.0034 0.0034
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0615 0.0637 0.0637
Brugia malayi hypothetical protein 0.0091 0.0062 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0126 0.1278
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0006 0.0064
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.003 0.003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.0129 0.0128
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0788 0.0827 0.0827
Plasmodium vivax ataxin-2 like protein, putative 0.0127 0.0102 0.1227
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0136 0.0136
Echinococcus granulosus histone lysine methyltransferase setb 0.0256 0.0243 0.0243
Loa Loa (eye worm) RNA binding protein 0.0062 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Trypanosoma brucei glucosidase, putative 0.0035 0.0001 0.0005
Schistosoma mansoni neurotransmitter gated ion channel 0.0039 0.0005 0.0005
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0003 0.0003
Brugia malayi PHD-finger family protein 0.0036 0.0002 0.0002
Plasmodium falciparum glutathione reductase 0.0047 0.0013 0.016
Echinococcus granulosus zinc finger protein 0.8353 0.9135 0.9135
Leishmania major cathepsin L-like protease 0.0071 0.004 0.0402
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0079 0.0803
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0016 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0006 0.0015
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0044 0.001 0.0157
Mycobacterium ulcerans acetylornithine aminotransferase 0.0065 0.0034 0.0634
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0001 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0033 0.0032
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0009 0.0008
Echinococcus granulosus lamin 0.0081 0.0051 0.005
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0006 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0296 0.0287 0.0287
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0006 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0149 0.0126 0.0489
Brugia malayi MBOAT family protein 0.0788 0.0827 0.0827
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0225 0.0209 0.1141
Brugia malayi MH2 domain containing protein 0.074 0.0775 0.0775
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0006 0.0015
Toxoplasma gondii hypothetical protein 0.009 0.0061 0.0734
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0013 0.0043
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0065 0.0034 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Brugia malayi nuclear hormone receptor 0.0136 0.0112 0.0111
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0788 0.0827 0.0827
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0221 0.0205 0.0205
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0136 0.0112 0.0111
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0005 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0189 0.017 0.017
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0072 0.0041 0.0041
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.001 0.0101
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0112 0.0112
Entamoeba histolytica hypothetical protein 0.0049 0.0016 0.0194
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0092 0.0356
Trypanosoma cruzi hypothetical protein, conserved 0.0365 0.0363 0.3686
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.001 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0006 0.0064
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0027 0.0027
Loa Loa (eye worm) hhat protein 0.0788 0.0827 0.0827
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0233 0.0218 0.0218
Echinococcus granulosus expressed protein 0.0037 0.0003 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0365 0.0363 0.0363
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0205 0.0187 0.0187
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0037 0.0201
Mycobacterium tuberculosis Probable aminotransferase 0.046 0.0468 0.1845
Trypanosoma cruzi glycerol uptake protein, putative 0.0788 0.0827 0.8407
Echinococcus multilocularis expressed protein 0.0037 0.0003 0.0003
Loa Loa (eye worm) MBOAT family protein 0.0788 0.0827 0.0827
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0256 0.0243 0.0243
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0044 0.001 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0192 0.0173 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Schistosoma mansoni hypothetical protein 0.0042 0.0008 0.0008
Brugia malayi hypothetical protein 0.0941 0.0996 0.0996
Schistosoma mansoni hypothetical protein 0.0085 0.0056 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0079 0.0432
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0044 0.001 0.0119
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.001 0.0101
Schistosoma mansoni cpg binding protein 0.0386 0.0386 0.0386
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0033 0.0156
Loa Loa (eye worm) hypothetical protein 0.0081 0.0051 0.0051
Leishmania major cytochrome p450-like protein 0.0059 0.0027 0.027
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0788 0.0827 0.0827
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0002 0.0001
Onchocerca volvulus 0.0039 0.0005 0.0004
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0037 0.0003 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0027 0.7753
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0136 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0167 0.0146 0.0146
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0051 0.0051
Schistosoma mansoni myst-related protein 0.0049 0.0016 0.0016
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Brugia malayi tailless protein 0.0064 0.0033 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0256 0.0243 0.0243
Echinococcus granulosus tar DNA binding protein 0.0062 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0136 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0079 0.0049 0.0049
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0131 0.0106 0.1073
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0126 0.0126
Brugia malayi RNA binding protein 0.0062 0.003 0.003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0193 0.0174 0.1765
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0006 0.0082
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0788 0.0827 0.0827
Echinococcus multilocularis nuclear receptor nhr 48 0.0064 0.0033 0.0032
Leishmania major hypothetical protein, conserved 0.0127 0.0102 0.1032
Toxoplasma gondii heat shock protein 90, putative 0.0035 0 0.0002
Echinococcus multilocularis protein dispatched 1 0.0101 0.0073 0.0073
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0002 0.0022
Brugia malayi nuclear receptor RXR 0.0072 0.0041 0.0041
Echinococcus granulosus jumonji domain containing protein 0.0043 0.001 0.001
Schistosoma mansoni cpg binding protein 0.0412 0.0414 0.0414
Onchocerca volvulus 0.0149 0.0126 0.0668
Schistosoma mansoni myst-related protein 0.0049 0.0016 0.0016
Echinococcus granulosus microtubule associated protein 2 0.2079 0.2245 0.2245
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0027 0.0271
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0027 0.0271
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0033 0.0333
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0104 0.0076 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0033 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0099 0.007 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0238 0.1302
Brugia malayi nuclear hormone receptor family member nhr-6 0.0064 0.0033 0.0032
Leishmania major mitochondrial DNA polymerase beta 0.093 0.0984 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0027 0.0096
Entamoeba histolytica acyl-coA synthetase, putative 0.0149 0.0126 0.1519
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0006 0.0082
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0788 0.0827 0.0827
Echinococcus granulosus sterol O acyltransferase 1 0.0788 0.0827 0.0827
Loa Loa (eye worm) transcription factor SMAD2 0.074 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0037 0.0003 0.0003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0149 0.0126 0.2482
Entamoeba histolytica hypothetical protein 0.0047 0.0013 0.0157
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0079 0.1578
Schistosoma mansoni nAChR subunit 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0065 0.0034 0.0124
Echinococcus multilocularis 0.004 0.0006 0.0006
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0044 0.001 0.003
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.0139 0.0139
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0032 0.0032
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0089 0.0059 0.0059
Trypanosoma brucei heat shock protein, putative 0.0035 0 0.0001
Onchocerca volvulus 0.0189 0.017 0.091
Loa Loa (eye worm) hypothetical protein 0.0189 0.017 0.017
Trypanosoma cruzi glycerol uptake protein, putative 0.0788 0.0827 0.8407
Trypanosoma brucei protein kinase, putative 0.0107 0.0079 0.0803
Loa Loa (eye worm) follicle stimulating hormone receptor 0.121 0.129 0.129
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0294 0.0285 0.0285
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0027 0.0934
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0225 0.0209 0.0209
Brugia malayi Inositol-1 0.0037 0.0002 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.044 0.0446 0.4528
Trichomonas vaginalis D-aminoacylase, putative 0.0365 0.0363 0.1984
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0131 0.0106 0.1073
Schistosoma mansoni intermediate filament proteins 0.0081 0.0051 0.0051
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0023 0.0233
Brugia malayi MAP kinase sur-1 0.0107 0.0079 0.0079
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0013 0.0013
Brugia malayi MBOAT family protein 0.0788 0.0827 0.0827
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0001 0.0007
Brugia malayi Cytochrome P450 family protein 0.0059 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0432 0.0437 0.0436
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Trichomonas vaginalis penicillin-binding protein, putative 0.0365 0.0363 0.1984
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0126 0.1519
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0079 0.0304
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0027 0.0271
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0126 0.2591
Mycobacterium tuberculosis Probable esterase LipL 0.0365 0.0363 0.1429
Mycobacterium tuberculosis Conserved protein 0.0365 0.0363 0.1429
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0044 0.001 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Trypanosoma brucei unspecified product 0.0041 0.0007 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0513 0.0526 0.0526
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.093 0.0984 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.093 0.0984 1
Echinococcus multilocularis ornithine aminotransferase 0.0065 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0149 0.0126 0.0126
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0072 0.0041 0.0041
Schistosoma mansoni chromobox protein 0.0068 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0193 0.0174 0.095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0136 0.0112 0.0112
Mycobacterium ulcerans hypothetical protein 0.049 0.05 1
Toxoplasma gondii hypothetical protein 0.009 0.0061 0.0734
Schistosoma mansoni hypothetical protein 0.0309 0.0302 0.0302
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0102 0.1227
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0003
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0788 0.0827 0.0827
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0072 0.0041 0.0041
Schistosoma mansoni lipoxygenase 0.0131 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0149 0.0126 0.0126
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0189 0.017 0.017
Schistosoma mansoni tar DNA-binding protein 0.0062 0.003 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0126 0.1278
Schistosoma mansoni hypothetical protein 0.0064 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0472 0.0481 0.5811
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0134 0.0109 0.2148
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0018 0.0018
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0016 0.0065
Brugia malayi MBOAT family protein 0.0788 0.0827 0.0827
Echinococcus multilocularis smad 0.005 0.0017 0.0017
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0079 0.0803
Echinococcus granulosus neuropeptide receptor A26 0.0501 0.0513 0.0512
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0225 0.0209 0.212
Plasmodium falciparum ornithine aminotransferase 0.0065 0.0034 0.0408
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0189 0.017 0.017
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0079 0.0803
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0189 0.017 0.017
Mycobacterium leprae conserved hypothetical protein 0.0365 0.0363 0.7728
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0649 0.0675 0.0675
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0006 0.0082
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0065 0.0034 0.2948
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0044 0.001 0.003
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0032 0.0032
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0065 0.0034 0.0596
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0225 0.0209 0.1141
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Mycobacterium ulcerans glutaminase 0.0284 0.0274 0.5451
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0018 0.0096
Echinococcus multilocularis dnaJ subfamily B 0.3427 0.3726 0.3725
Loa Loa (eye worm) hypothetical protein 0.0941 0.0996 0.0996
Echinococcus multilocularis ecdysone induced protein 78C 0.0136 0.0112 0.0111
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0001 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.004 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0046 0.0013 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0006 0.0015
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0 0.0001
Brugia malayi nuclear receptor NHR-88 0.0136 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0127 0.0102 0.0102
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Toxoplasma gondii GAF domain-containing protein 0.009 0.0061 0.0734
Loa Loa (eye worm) hypothetical protein 0.0087 0.0057 0.0057
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0007 0.0038
Echinococcus multilocularis glycine receptor subunit beta 0.0072 0.0041 0.0041
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0023 0.0023
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0079 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Echinococcus granulosus importin subunit beta 1 0.0058 0.0025 0.0025
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0065 0.0034 0.0634
Leishmania major trypanothione reductase 0.0047 0.0013 0.0134
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0225 0.0209 0.212
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0126 0.2591
Echinococcus granulosus cpg binding protein 0.0412 0.0414 0.0414
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0017 0.0017
Echinococcus multilocularis Smad4 0.005 0.0017 0.0017
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0225 0.0209 0.212
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0023 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0513 0.0526 0.0526
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0078 0.0298
Brugia malayi Thioredoxin reductase 0.0047 0.0013 0.0013
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0225 0.0209 0.212
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0009 0.0102
Toxoplasma gondii propionate-CoA ligase 0.0044 0.001 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0099 0.007 0.0384
Brugia malayi photoreceptor-specific nuclear receptor 0.0136 0.0112 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus FTZ F1 alpha 0.0136 0.0112 0.0111
Trichomonas vaginalis ran, putative 0.0042 0.0009 0.0046
Toxoplasma gondii ABC1 family protein 0.0365 0.0363 0.4385
Plasmodium vivax acetyl-CoA synthetase, putative 0.0044 0.001 0.0121
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0032 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0136 0.0112 0.0111
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0136 0.0112 0.0112
Trichomonas vaginalis penicillin-binding protein, putative 0.0365 0.0363 0.1984
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0027 0.0027
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0262 0.0249 0.1364
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0112 0.0111
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0075 0.0074
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Schistosoma mansoni zinc finger protein 0.0066 0.0034 0.0034
Schistosoma mansoni inositol monophosphatase 0.0037 0.0002 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0023 0.0023
Echinococcus multilocularis protein patched 0.0089 0.0059 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0072 0.0041 0.0041
Echinococcus multilocularis Aminotransferase class III 0.0065 0.0034 0.0034
Loa Loa (eye worm) LGC-31 protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0206 0.0188 0.0188
Mycobacterium tuberculosis Conserved hypothetical protein 0.049 0.05 0.1975
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0788 0.0827 1
Mycobacterium ulcerans esterase/lipase LipP 0.0365 0.0363 0.7239
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0246 0.0232 0.0232
Echinococcus granulosus o acyltransferase membrane bound domain 0.0788 0.0827 0.0827
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0002 0.0022
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0136 0.0112 0.0111
Brugia malayi Hhat protein 0.0788 0.0827 0.0827
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0023 0.0023
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0002 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Loa Loa (eye worm) hypothetical protein 0.0788 0.0827 0.0827
Giardia lamblia DINP protein human, muc B family 0.0059 0.0027 0.0935
Loa Loa (eye worm) hypothetical protein 0.0111 0.0085 0.0085
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0041 0.0222
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0006 0.0015
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0208 0.0191 0.0191
Schistosoma mansoni nuclear receptor nhr-48 0.0064 0.0033 0.0033
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0001 0.0003
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Brugia malayi Cytochrome P450 family protein 0.004 0.0006 0.0006
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0013 0.016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0075 0.0074
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Loa Loa (eye worm) hypothetical protein 0.0649 0.0675 0.0675
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0099 0.0071 0.0071
Leishmania major glycerol uptake protein, putative 0.0788 0.0827 0.8407
Schistosoma mansoni hypothetical protein 0.0615 0.0637 0.0637
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0193 0.0174 0.0174
Brugia malayi Cytochrome P450 family protein 0.0159 0.0136 0.0136
Echinococcus multilocularis transcription factor btf3 0.0035 0.0001 0.0001
Plasmodium falciparum zinc finger protein, putative 0.0049 0.0016 0.0195
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0035 0 0.0000041849
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0136 0.0112 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0112 0.0111
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0035 0 0.0000041849
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0788 0.0827 0.0827
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0065 0.0034 0.0634
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.0027 0.027
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0788 0.0827 1
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.004 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0004 0.0021
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0035 0 0.0000041849
Brugia malayi Niemann-Pick C1 protein precursor 0.0207 0.0189 0.0189
Schistosoma mansoni ran 0.0042 0.0009 0.0009
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0135 0.011 0.06
Brugia malayi Bromodomain containing protein 0.0082 0.0052 0.0052
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0042 0.0042
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Plasmodium falciparum importin beta, putative 0.0058 0.0025 0.0304
Entamoeba histolytica hypothetical protein 0.0472 0.0481 0.5811
Brugia malayi nuclear receptor NHR-67 0.0064 0.0033 0.0032
Echinococcus granulosus neuropeptide s receptor 0.0501 0.0513 0.0512
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0058 0.0317
Loa Loa (eye worm) hypothetical protein 0.0099 0.0071 0.0071
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0079 0.0955
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0013 0.0013
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0079 0.0079
Schistosoma mansoni inositol monophosphatase 0.0037 0.0002 0.0002
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0035 0 0.0000041849
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Trypanosoma cruzi GUP1, putative 0.0788 0.0827 0.8407
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0072 0.0041 0.0041
Treponema pallidum alginate O-acetylation protein (algI) 0.0788 0.0827 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0006 0.0082
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0788 0.0827 0.0827
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0225 0.0209 0.0209
Schistosoma mansoni survival motor neuron protein 0.0192 0.0173 0.0173
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0072 0.0041 0.0041
Brugia malayi chromobox protein homolog 3 0.0038 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0136 0.0112 0.0111
Echinococcus multilocularis thyroid hormone receptor alpha 0.0136 0.0112 0.0111
Entamoeba histolytica hypothetical protein 0.0788 0.0827 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0788 0.0827 0.0827
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0003 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0059 0.0027 0.0027
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0046 0.0013 0.33
Brugia malayi Nuclear hormone receptor-like 1 0.0136 0.0112 0.0111
Leishmania major importin beta-1 subunit, putative 0.0047 0.0013 0.0134
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0285 0.156
Schistosoma mansoni smad1 5 8 and 0.005 0.0017 0.0017
Schistosoma mansoni sterol O-acyltransferase 1 0.0788 0.0827 0.0827
Toxoplasma gondii histone lysine methyltransferase SET1 0.0748 0.0783 0.9469
Schistosoma mansoni ap endonuclease 0.0059 0.0027 0.0027
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0788 0.0827 0.0827
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0238 0.0238
Echinococcus granulosus RUN 0.0064 0.0032 0.0032
Trypanosoma brucei trypanothione reductase 0.0047 0.0013 0.0134
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0079 0.0304
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0001 0.0006
Brugia malayi serine/threonine-protein kinase plk-2 0.0294 0.0285 0.0285
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0046 0.0013 0.004
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0035 0 0.0000041849
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.004 0.0402
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0081 0.0051 0.005
Echinococcus granulosus o acyltransferase membrane bound domain 0.0788 0.0827 0.0827
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0002 0.0001
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.0165 0.0885
Trypanosoma brucei polo-like protein kinase 0.0294 0.0285 0.2899
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0018 0.0212
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0193 0.0174 0.0174
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0044 0.001 0.0121
Brugia malayi latrophilin 2 splice variant baaae 0.0214 0.0197 0.0197
Onchocerca volvulus 0.0547 0.0563 0.3065
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0072 0.0041 0.0041
Onchocerca volvulus Huntingtin homolog 0.0649 0.0675 0.3681
Echinococcus multilocularis Niemann Pick C1 protein 0.0295 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0136 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.001 0.003
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0035 0 0.0000041849
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0059 0.0027 0.0027
Echinococcus multilocularis lamin 0.0081 0.0051 0.005
Mycobacterium ulcerans beta-lactamase 0.0365 0.0363 0.7239
Onchocerca volvulus Protein ultraspiracle homolog 0.0136 0.0112 0.0589
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0002 0.0019
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0079 0.0304
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0143 0.0782
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0071 0.004 0.0402
Toxoplasma gondii aldehyde dehydrogenase 0.0432 0.0437 0.5278
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0079 0.0803
Plasmodium falciparum acyl-CoA synthetase 0.0111 0.0085 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0026 0.014
Trichomonas vaginalis set domain proteins, putative 0.1699 0.1828 1
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0788 0.0827 0.0827
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.004 0.0402
Loa Loa (eye worm) beta-lactamase 0.0365 0.0363 0.0363
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0072 0.0041 0.0041
Onchocerca volvulus Bile acid receptor homolog 0.0136 0.0112 0.0589
Echinococcus multilocularis peregrin 0.004 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0412 0.0414 0.0414
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Loa Loa (eye worm) hypothetical protein 0.0054 0.0021 0.0021
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0365 0.0363 0.0363
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.001 0.0055
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0059 0.0059
Brugia malayi hypothetical protein 0.0064 0.0032 0.0032
Entamoeba histolytica serine/threonine protein kinase, putative 0.0294 0.0285 0.3447
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0788 0.0827 0.0827
Schistosoma mansoni nuclear receptor 0.0064 0.0033 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.001 0.0157
Leishmania major glycerol uptake protein, putative 0.0788 0.0827 0.8407
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.001 0.003
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Schistosoma mansoni hypothetical protein 0.0085 0.0056 0.0056
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0072 0.0041 0.0041
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0193 0.0174 0.2098
Trypanosoma brucei hypothetical protein, conserved 0.0365 0.0363 0.3686
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.004 0.0402
Echinococcus multilocularis zinc finger protein 0.8353 0.9135 0.9135
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0072 0.0041 0.0041
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0006 0.0082
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0193 0.0174 0.0174
Mycobacterium ulcerans hypothetical protein 0.0149 0.0126 0.2482
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0006 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0136 0.0112 0.0589
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0137 0.1392
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0432 0.0437 0.0436
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0025 0.0304
Mycobacterium ulcerans acetyl-CoA synthetase 0.0044 0.001 0.0157
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0027 0.0146
Schistosoma mansoni retinoic acid receptor RXR 0.0136 0.0112 0.0112
Loa Loa (eye worm) oxidoreductase 0.0044 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0112 0.0111
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0258 0.0245 0.0245
Brugia malayi hypothetical protein 0.0072 0.0041 0.0041
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0225 0.0209 0.212
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0256 0.0243 0.0243
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0221 0.0205 0.248
Trichomonas vaginalis D-aminoacylase, putative 0.0365 0.0363 0.1984
Echinococcus granulosus peregrin 0.004 0.0006 0.0006
Echinococcus multilocularis L aminoadipate semialdehyde 0.0164 0.0142 0.0142
Loa Loa (eye worm) TAR-binding protein 0.0062 0.003 0.003
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0064 0.0033 0.0032
Schistosoma mansoni lamin 0.0081 0.0051 0.0051
Trypanosoma cruzi polo-like protein kinase, putative 0.0294 0.0285 0.2899
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0189 0.017 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0153 0.0836
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0008 0.0096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0041 0.0222
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.0027 0.027
Brugia malayi PHD-finger family protein 0.0076 0.0046 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0041 0.0041
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0238 0.0238
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0189 0.017 0.017
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0 0.0001
Loa Loa (eye worm) CYP4Cod1 0.0059 0.0027 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0788 0.0827 0.8407
Brugia malayi hypothetical protein 0.0649 0.0675 0.0675
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0079 0.0432
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0002 0.0016
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Mycobacterium ulcerans putative regulatory protein 0.009 0.0061 0.1175
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0017 0.0017
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0072 0.0041 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.0313 0.0306 0.0306
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0079 0.0803
Brugia malayi CHE-14 protein 0.0089 0.0059 0.0059
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.001 0.0101
Schistosoma mansoni hypothetical protein 0.0099 0.0071 0.0071
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0001 0.0004
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0027 0.0271
Plasmodium falciparum GAF domain-related protein, putative 0.009 0.0061 0.0734
Schistosoma mansoni rotamase 0.0037 0.0003 0.0003
Brugia malayi orphan nuclear receptor NR2E1 0.0064 0.0033 0.0032
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0114 0.0087 0.0087
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0072 0.0041 0.0041
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0256 0.0243 0.0243
Brugia malayi ecdysteroid receptor 0.0136 0.0112 0.0111
Plasmodium falciparum thioredoxin reductase 0.0047 0.0013 0.016
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0027 0.0027
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0002 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0079 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0006 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0126 0.2482
Leishmania major heat shock protein 83-1 0.0035 0 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0432 0.0437 0.0437
Echinococcus multilocularis musashi 0.0081 0.0051 0.005
Trichomonas vaginalis transmembrane protein nessy, putative 0.0788 0.0827 0.4525
Echinococcus multilocularis GPCR, family 2 0.0099 0.0071 0.0071
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0046 0.0013 0.0209
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0006 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0513 0.0526 0.0526
Echinococcus multilocularis FTZ F1 alpha 0.0136 0.0112 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0788 0.0827 0.4525
Brugia malayi conserved hypotetical protein 0.0064 0.0033 0.0032
Brugia malayi Muscleblind-like protein 0.2155 0.2328 0.2328
Brugia malayi glutaminase DH11.1 0.0284 0.0274 0.0274
Mycobacterium tuberculosis Probable lipase LipE 0.0365 0.0363 0.1429
Loa Loa (eye worm) hypothetical protein 0.0365 0.0363 0.0363
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0225 0.0209 0.1141
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.0025 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0036 0.0002 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0025 0.0255
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0205 0.0187 0.0187
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.001 0.001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0125 0.0099 0.0541
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0099 0.007 0.0384

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

27 literature references were collected for this gene.

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