Detailed information for compound 60022

Basic information

Technical information
  • TDR Targets ID: 60022
  • Name: (NE)-N-[dimethylamino(phenyl)methylidene]-N'- phenylmorpholine-4-carboximidamide
  • MW: 336.431 | Formula: C20H24N4O
  • H donors: 0 H acceptors: 0 LogP: 2.92 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(/C(=N/C(=N/c1ccccc1)/N1CCOCC1)/c1ccccc1)C
  • InChi: 1S/C20H24N4O/c1-23(2)19(17-9-5-3-6-10-17)22-20(24-13-15-25-16-14-24)21-18-11-7-4-8-12-18/h3-12H,13-16H2,1-2H3/b21-20-,22-19+
  • InChiKey: HSYLJQJEKUVSPG-QCKHJMTRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (NE)-N-[dimethylamino(phenyl)methylene]-N'-phenyl-morpholine-4-carboxamidine
  • (NE)-N-[dimethylamino(phenyl)methylene]-N'-phenyl-4-morpholinecarboxamidine
  • (NE)-N-[dimethylamino(phenyl)methylidene]-N'-phenyl-morpholine-4-carboximidamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus oxysterol binding protein 3 0.0127 0.0035 0.0013
Brugia malayi Stress-activated protein kinase jnk-1 0.085 0.2857 0.2998
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Giardia lamblia Kinase, CMGC DYRK 0.0209 0.0356 0.0441
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Trichomonas vaginalis STE family protein kinase 0.0208 0.0354 0.0373
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Loa Loa (eye worm) PH domain-containing protein 0.0127 0.0035 0.0014
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0599 0.1877 0.4661
Loa Loa (eye worm) TK protein kinase 0.0318 0.0783 0.0805
Schistosoma mansoni serine/threonine protein kinase 0.1297 0.4599 0.7802
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0408 0.1132 0.1606
Schistosoma mansoni goodpasture antigen-binding protein 0.0127 0.0035 0.0033
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0315 0.0768 0.1411
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0416 0.1164 0.1652
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0123 0.0022 0.0011
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0127 0.0035 0.0014
Entamoeba histolytica protein kinase 2, putative 0.1502 0.5396 0.5681
Echinococcus granulosus tyrosine kinase 0.0196 0.0306 0.0284
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.052 0.1569 0.1636
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.1912 0.2017
Loa Loa (eye worm) hypothetical protein 0.0172 0.0211 0.02
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.114 0.3987 0.4185
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0127 0.0035 0.0037
Echinococcus multilocularis serine:threonine protein kinase N2 0.1303 0.462 0.6651
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0788 0.2612 0.2739
Toxoplasma gondii AGC kinase 0.114 0.3987 0.4421
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0127 0.0035 0.0014
Onchocerca volvulus Tyrosine kinase homolog 0.1359 0.484 1
Echinococcus granulosus Pleckstrin y 0.0127 0.0035 0.0013
Onchocerca volvulus 0.0156 0.0151 0.0241
Trichomonas vaginalis STE family protein kinase 0.0315 0.0768 0.081
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0235 0.0458 0.0754
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.114 0.3987 0.4185
Schistosoma mansoni growth factor receptor-bound protein 0.0172 0.0211 0.0333
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0261 0.0561 0.057
Echinococcus granulosus oxysterol binding protein 1 0.0127 0.0035 0.0013
Brugia malayi hypothetical protein 0.0514 0.1544 0.161
Echinococcus granulosus serine:threonine protein kinase 3 0.0571 0.1766 0.1748
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1291 0.4574 0.6584
Brugia malayi cyclin-dependent kinase 9 0.0147 0.0116 0.0099
Schistosoma mansoni tyrosine kinase 0.049 0.1453 0.2447
Echinococcus granulosus mitogen activated protein kinase 0.0261 0.0561 0.054
Schistosoma mansoni protein kinase 0.0266 0.058 0.096
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Schistosoma mansoni hypothetical protein 0.0125 0.0027 0.002
Schistosoma mansoni vesicular amine transporter 0.0235 0.0458 0.0754
Echinococcus multilocularis beta 1 syntrophin 0.0131 0.0052 0.0043
Onchocerca volvulus 0.026 0.0554 0.1079
Echinococcus multilocularis epidermal growth factor receptor 0.0987 0.3391 0.4872
Echinococcus multilocularis oxysterol binding protein 1 0.0127 0.0035 0.0019
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0322 0.0797 0.112
Trichomonas vaginalis STE family protein kinase 0.0205 0.0342 0.0361
Echinococcus multilocularis activin receptor type 0.0613 0.193 0.276
Echinococcus granulosus protein kinase shaggy 0.0408 0.1132 0.1113
Brugia malayi Protein kinase domain containing protein 0.0701 0.2273 0.238
Trypanosoma cruzi casein kinase, putative 0.026 0.0554 0.0886
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0514 0.1544 0.2202
Brugia malayi MAX-1A 0.0127 0.0035 0.0014
Echinococcus multilocularis pleckstrin y domain containing family A 0.0127 0.0035 0.0019
Onchocerca volvulus 0.0196 0.0306 0.0563
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0803 0.2673 0.3834
Echinococcus multilocularis Pleckstrin y 0.0127 0.0035 0.0019
Echinococcus granulosus neuroglian 0.0292 0.0681 0.066
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0561 0.0592
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.114 0.3987 0.7372
Schistosoma mansoni hypothetical protein 0.0127 0.0035 0.0033
Brugia malayi Variant SH3 domain containing protein 0.0233 0.0448 0.045
Brugia malayi Protein kinase domain containing protein 0.0288 0.0664 0.0678
Loa Loa (eye worm) protein kinase domain-containing protein 0.0288 0.0665 0.0679
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0482 0.1421 0.1479
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Loa Loa (eye worm) AGC/PKA protein kinase 0.114 0.3987 0.4193
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0194 0.0298 0.0302
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0399 0.1096 0.2019
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.018 0.0244 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0399 0.1096 0.1839
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Schistosoma mansoni serine/threonine protein kinase 0.054 0.1648 0.2778
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Giardia lamblia Kinase, NEK 0.0315 0.0768 0.1223
Schistosoma mansoni serine/threonine-protein kinase 0.1628 0.589 1
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0588 0.1834 0.1815
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0261 0.0561 0.0898
Loa Loa (eye worm) hypothetical protein 0.0777 0.2569 0.2694
Echinococcus granulosus serine:threonine protein kinase 0.0268 0.0586 0.0565
Brugia malayi hypothetical protein 0.0196 0.0306 0.03
Schistosoma mansoni protein kinase 0.0162 0.0174 0.027
Echinococcus granulosus cGMP dependent protein kinase 1 0.0204 0.0338 0.0316
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0235 0.0458 0.0461
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0525 0.1589 0.1657
Schistosoma mansoni hypothetical protein 0.0182 0.025 0.0399
Schistosoma mansoni goodpasture antigen-binding protein 0.0127 0.0035 0.0033
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0172 0.0211 0.02
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0942 0.3215 0.3392
Brugia malayi Protein kinase domain containing protein 0.0298 0.0703 0.072
Echinococcus multilocularis Pleckstrin y 0.0127 0.0035 0.0019
Echinococcus multilocularis neuroglian 0.0292 0.0681 0.0952
Echinococcus granulosus serine:threonine protein kinase N2 0.1303 0.462 0.4608
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0133 0.0059 0.0036
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.049 0.1453 0.207
Onchocerca volvulus 0.0196 0.0306 0.0563
Loa Loa (eye worm) hypothetical protein 0.0367 0.0973 0.1005
Entamoeba histolytica protein kinase, putative 0.0149 0.0123 0.0102
Loa Loa (eye worm) hypothetical protein 0.0202 0.033 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0131 0.0051 0.0059
Brugia malayi putative serine/threonine kinase SADA gamma 0.0206 0.0343 0.0339
Brugia malayi bone morphogenetic protein type 1 receptor 0.018 0.0244 0.0235
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0204 0.0338 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0228 0.0362
Echinococcus granulosus rho-associated protein kinase 1 0.0715 0.2331 0.2314
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0524 0.1584 0.2259
Brugia malayi Protein kinase domain containing protein 0.0643 0.2049 0.2144
Echinococcus granulosus tyrosine protein kinase shark 0.0424 0.1194 0.1174
Echinococcus granulosus beta 1 syntrophin 0.0131 0.0052 0.003
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Entamoeba histolytica protein kinase domain containing protein 0.0147 0.0116 0.0094
Onchocerca volvulus 0.0196 0.0306 0.0563
Schistosoma mansoni hypothetical protein 0.0173 0.0216 0.0342
Onchocerca volvulus 0.0308 0.0743 0.1474
Brugia malayi Egg laying defective protein 4 0.0204 0.0338 0.0333
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Echinococcus granulosus casein kinase I alpha 0.026 0.0554 0.0533
Schistosoma mansoni hypothetical protein 0.0127 0.0035 0.0033
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.054 0.1648 0.1629
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0194 0.0298 0.0449
Trichomonas vaginalis AGC family protein kinase 0.0399 0.1096 0.1156
Schistosoma mansoni nck2/grb4 0.0172 0.0211 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0715 0.2331 0.3941
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0209 0.0356 0.0367
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0201 0.0324 0.0436
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.1502 0.5396 1
Schistosoma mansoni protein kinase 0.051 0.1528 0.2575
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Entamoeba histolytica protein kinase, putative 0.0222 0.0409 0.0404
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0199 0.0316 0.0425
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Plasmodium vivax serine/threonine protein kinase, putative 0.0149 0.0123 0.0214
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0458 0.0483
Echinococcus granulosus cyclin dependent kinase 0.0463 0.1346 0.1327
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.3974
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0588 0.1834 0.262
Onchocerca volvulus 0.0196 0.0306 0.0563
Schistosoma mansoni growth factor receptor-bound protein 0.0176 0.0227 0.0359
Echinococcus granulosus hypothetical protein 0.0202 0.033 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0487 0.0802
Trypanosoma brucei polo-like protein kinase 0.0599 0.1877 0.195
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Brugia malayi Kinase associated domain 1 family protein 0.0173 0.0216 0.0205
Echinococcus multilocularis cyclin dependent kinase 9 0.0156 0.0151 0.0186
Brugia malayi Protein kinase domain containing protein 0.0196 0.0306 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0643 0.2049 0.3462
Brugia malayi Sex muscle abnormal protein 5 0.0172 0.0211 0.02
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.114 0.3987 0.4193
Echinococcus granulosus calcium activated potassium channel 0.0269 0.059 0.0569
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1318 0.4679 0.6736
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0408 0.1132 0.1874
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0208 0.0354 0.0479
Schistosoma mansoni protein kinase 0.018 0.0244 0.0389
Echinococcus multilocularis serine:threonine protein kinase 0.0268 0.0586 0.0815
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0127 0.0035 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.114 0.3987 0.4185
Brugia malayi Hr1 repeat family protein 0.1303 0.462 0.4862
Echinococcus granulosus tyrosine protein kinase Srms 0.0631 0.2001 0.1983
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0137 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Echinococcus granulosus mitogen activated protein kinase 14 0.0507 0.152 0.1501
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0222 0.0409 0.0638
Entamoeba histolytica PH domain containing protein kinase, putative 0.0222 0.0409 0.0404
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Entamoeba histolytica casein kinase 1, putative 0.026 0.0554 0.0557
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0717 0.2337 0.3349
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0176 0.0228 0.0298
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Echinococcus granulosus Vam6:Vps39 protein 0.0217 0.0388 0.0366
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0209 0.0356 0.0339
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0127 0.0035 0.0019
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0441 0.1261 0.1241
Trypanosoma cruzi NIMA-related kinase, putative 0.0222 0.0409 0.0638
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0209 0.0356 0.0353
Schistosoma mansoni unc-13 (munc13) 0.0135 0.0067 0.0087
Leishmania major protein kinase A catalytic subunit isoform 1 0.114 0.3987 1
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0127 0.0035 0.0037
Echinococcus multilocularis serine:threonine protein kinase N2 0.1165 0.4082 0.5872
Loa Loa (eye worm) hypothetical protein 0.0273 0.0607 0.0619
Loa Loa (eye worm) hypothetical protein 0.0335 0.0848 0.0873
Entamoeba histolytica hypothetical protein, conserved 0.0127 0.0035 0.0009
Schistosoma mansoni hypothetical protein 0.0173 0.0216 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0166 0.0188 0.0175
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0452 0.1302 0.1851
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0394 0.1077 0.1115
Echinococcus multilocularis GRB2 associated binding protein 3 0.0127 0.0035 0.0019
Brugia malayi Protein kinase domain containing protein 0.0864 0.291 0.3054
Echinococcus multilocularis Rho GTPase activating protein 24 0.0127 0.0035 0.0019
Trypanosoma brucei protein kinase, putative 0.0408 0.1132 0.1162
Echinococcus granulosus tyrosine kinase 0.0416 0.1164 0.1145
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0463 0.1346 0.14
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.026 0.0554 0.0562
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0163 0.0177 0.0155
Loa Loa (eye worm) hypothetical protein 0.0217 0.0388 0.0386
Loa Loa (eye worm) hypothetical protein 0.0421 0.1184 0.1229
Brugia malayi Serine/threonine-protein kinase SULU 0.0514 0.1544 0.161
Loa Loa (eye worm) hypothetical protein 0.0433 0.1229 0.1276
Schistosoma mansoni ste20-related kinase 0.0461 0.1339 0.2252
Schistosoma mansoni tyrosine kinase 0.027 0.0595 0.0985
Echinococcus granulosus casein kinase I delta 0.026 0.0554 0.0533
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Giardia lamblia Kinase, CDC7 0.0156 0.0151 0.0053
Onchocerca volvulus 0.0133 0.0059 0.0049
Echinococcus granulosus Rho GTPase activating protein 24 0.0127 0.0035 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0222 0.0409 0.0396
Brugia malayi RhoGAP domain containing protein 0.0125 0.0027 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.046 0.0757
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0687 0.0725
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0414 0.1155 0.1135
Onchocerca volvulus 0.062 0.1957 0.4
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Leishmania major protein kinase A catalytic subunit isoform 2 0.114 0.3987 1
Loa Loa (eye worm) hypothetical protein 0.0217 0.0388 0.0386
Loa Loa (eye worm) uncoordinated protein 104 0.0127 0.0035 0.0014
Echinococcus granulosus raf serine:threonine protein kinase 0.0223 0.041 0.0389
Brugia malayi Protein kinase domain containing protein 0.1016 0.3504 0.3682
Echinococcus granulosus TGF beta receptor type 1 0.0178 0.0235 0.0213
Entamoeba histolytica PH domain containing protein 0.0127 0.0035 0.0009
Toxoplasma gondii hypothetical protein 0.0127 0.0035 0.0009
Plasmodium vivax calcium-dependent protein kinase, putative 0.0235 0.0458 0.0835
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0127 0.0035 0.0019
Entamoeba histolytica hypothetical protein 0.0201 0.0324 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0151 0.0159
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0199 0.0316 0.0295
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0176 0.0228 0.0298
Schistosoma mansoni protein kinase 0.0717 0.2337 0.3952
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Brugia malayi Protein kinase domain containing protein 0.0196 0.0306 0.03
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0172 0.0211 0.02
Brugia malayi Tyrosine-protein kinase abl-1 0.0445 0.1277 0.1327
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0458 0.0753
Onchocerca volvulus 0.1152 0.4034 0.8322
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0151 0.0159
Brugia malayi p70 ribosomal S6 kinase beta 0.2422 0.8985 0.9478
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.1453 0.1434
Brugia malayi Protein kinase domain containing protein 0.0937 0.3194 0.3354
Echinococcus multilocularis Glutaredoxin protein 5 0.1406 0.5023 0.7233
Entamoeba histolytica PH domain containing protein kinase, putative 0.1267 0.4481 0.4712
Brugia malayi intracellular kinase 0.0408 0.1132 0.1174
Plasmodium falciparum glycogen synthase kinase 3 0.0408 0.1132 0.2047
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0654 0.2092 0.2994
Onchocerca volvulus 0.0463 0.1348 0.2731
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.5736
Loa Loa (eye worm) TK/ABL protein kinase 0.0654 0.2092 0.2188
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0127 0.0035 0.0013
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0206 0.0343 0.0464
Loa Loa (eye worm) hypothetical protein 0.0308 0.0743 0.0762
Brugia malayi diacylglycerol kinase 0.0125 0.0027 0.0005
Echinococcus granulosus titin 0.0176 0.0228 0.0206
Echinococcus multilocularis epidermal growth factor receptor 0.0692 0.224 0.3208
Loa Loa (eye worm) hypothetical protein 0.019 0.0281 0.0273
Schistosoma mansoni vav2 0.0349 0.0902 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0409 0.0431
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0539 0.1643 0.1714
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0313 0.0761 0.074
Entamoeba histolytica protein kinase, putative 0.0199 0.0316 0.0306
Trichomonas vaginalis AGC family protein kinase 0.0315 0.0768 0.081
Echinococcus multilocularis tyrosine protein kinase Fgr 0.049 0.1453 0.207
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0204 0.0338 0.0456
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.3974
Brugia malayi protein-tyrosine kinase 0.0416 0.1164 0.1208
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0409 0.0431
Brugia malayi MAP kinase sur-1 0.0261 0.0561 0.057
Echinococcus granulosus Protein kinase C brain isozyme 0.1318 0.4679 0.4667
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0266 0.058 0.0589
Onchocerca volvulus Serine\/threonine kinase homolog 0.0236 0.046 0.0884
Echinococcus multilocularis cytohesin 1 0.0127 0.0035 0.0019
Entamoeba histolytica protein kinase, putative 0.0394 0.1077 0.1111
Trichomonas vaginalis STE family protein kinase 0.0265 0.0575 0.0607
Giardia lamblia Kinase, STE STE20 0.0205 0.0342 0.0415
Trichomonas vaginalis AGC family protein kinase 0.0399 0.1096 0.1156
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0133 0.0059 0.0053
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.054 0.1648 0.2351
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0222 0.0409 0.0396
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1502 0.5396 0.9157
Echinococcus granulosus dual specificity 0.0209 0.0356 0.0334
Brugia malayi Fes/CIP4 homology domain containing protein 0.0237 0.0465 0.0468
Entamoeba histolytica PH domain containing protein kinase, putative 0.1267 0.4481 0.4712
Echinococcus multilocularis Diacylglycerol kinase theta 0.0125 0.0027 0.0007
Echinococcus granulosus NCK adaptor protein 0.0172 0.0211 0.019
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.114 0.3987 0.675
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0399 0.1096 0.1131
Echinococcus granulosus tyrosine protein kinase Blk 0.0416 0.1164 0.1145
Entamoeba histolytica hypothetical protein 0.0222 0.0409 0.0404
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0261 0.0561 0.0898
Echinococcus multilocularis Oxysterol binding protein 11 0.0127 0.0035 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.041 0.0672
Schistosoma mansoni hypothetical protein 0.0127 0.0035 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis rac serine:threonine kinase 0.1628 0.589 0.8488
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0183 0.0256 0.0235
Loa Loa (eye worm) AUR protein kinase 0.0399 0.1096 0.1135
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Loa Loa (eye worm) TK protein kinase 0.0416 0.1164 0.1208
Entamoeba histolytica protein kinase, putative 0.0194 0.0296 0.0285
Brugia malayi STE20-like kinase MST 0.0571 0.1766 0.1844
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0206 0.0343 0.0526
Echinococcus granulosus c-Jun N-terminal kinases 0.085 0.2857 0.2841
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0127 0.0035 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0409 0.0431
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Brugia malayi Protein kinase domain containing protein 0.0196 0.0306 0.03
Loa Loa (eye worm) hypothetical protein 0.0136 0.0071 0.0051
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0217 0.0388 0.0633
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0228 0.043 0.0409
Entamoeba histolytica protein kinase, putative 0.0399 0.1096 0.1131
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0127 0.0035 0.0014
Trichomonas vaginalis centaurin gamma, putative 0.0127 0.0035 0.0037
Entamoeba histolytica ARF GTPase activating protein, putative 0.0127 0.0035 0.0009
Echinococcus granulosus tyrosine protein kinase 0.0354 0.0922 0.0901
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0233 0.0448 0.045
Entamoeba histolytica hypothetical protein 0.0405 0.1122 0.1158
Schistosoma mansoni protein kinase C mu 0.0529 0.1603 0.2701
Plasmodium vivax unspecified product 0.0525 0.1589 0.2934
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.1502 0.5396 0.7774
Entamoeba histolytica protein kinase, putative 0.0289 0.0668 0.0678
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0394 0.1077 0.1103
Schistosoma mansoni serine/threonine protein kinase 0.085 0.2857 0.4837
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0228 0.043 0.0431
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0298 0.0703 0.0707
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.1016 0.3504 0.3489
Schistosoma mansoni serine/threonine protein kinase 0.0599 0.1877 0.3169
Schistosoma mansoni ephrin receptor 0.0234 0.0454 0.0746
Entamoeba histolytica protein kinase, putative 0.2422 0.8985 0.9478
Echinococcus granulosus serine/threonine protein kinase 0.1628 0.589 0.5881
Toxoplasma gondii aurora kinase 0.0399 0.1096 0.1193
Loa Loa (eye worm) AGC/PKG protein kinase 0.0204 0.0338 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Echinococcus multilocularis mitogen activated protein kinase 14 0.0507 0.152 0.2166
Schistosoma mansoni rap gtpase-activating protein 0.0217 0.0388 0.0633
Echinococcus granulosus DCC interacting protein 13 beta 0.0127 0.0035 0.0013
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0194 0.0298 0.0278
Brugia malayi Protein kinase domain containing protein 0.0938 0.3198 0.3358
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0529 0.1603 0.1671
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0123 0.0183
Echinococcus multilocularis mitogen activated protein kinase 11 0.0507 0.152 0.2166
Echinococcus multilocularis pdz domain containing protein 0.0148 0.0119 0.0139
Schistosoma mansoni cell adhesion molecule 0.0123 0.0022 0.0011
Brugia malayi SH2 domain containing protein 0.052 0.1567 0.1634
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0147 0.0116 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0338 0.0548
Echinococcus multilocularis dual specificity 0.0394 0.1077 0.1525
Trichomonas vaginalis AGC family protein kinase 0.1038 0.3589 0.3786
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0125 0.0027 0.0005
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0298 0.0703 0.072
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0862 0.2902 0.2886
Brugia malayi Cytohesin 3 0.0127 0.0035 0.0014
Echinococcus granulosus pleckstrin y domain containing family A 0.0127 0.0035 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Giardia lamblia Kinase, NEK 0.0315 0.0768 0.1223
Plasmodium falciparum calcium-dependent protein kinase 1 0.0235 0.0458 0.0789
Giardia lamblia Kinase, AGC PKA 0.1502 0.5396 1
Schistosoma mansoni zinc finger protein 0.0127 0.0035 0.0033
Trypanosoma brucei protein kinase, putative 0.0222 0.0409 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.1077 0.1806
Giardia lamblia Kinase, STE STE20 0.0208 0.0354 0.0437
Echinococcus granulosus tyrosine protein kinase Lyn 0.0586 0.1827 0.1808
Echinococcus granulosus fibroblast growth factor receptor 4 0.0527 0.1598 0.1579
Echinococcus granulosus dual specificity protein kinase clk2 0.0298 0.0703 0.0682
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Plasmodium falciparum serine/threonine protein kinase, putative 0.0399 0.1096 0.1978
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Brugia malayi Protein kinase domain containing protein 0.0788 0.2612 0.2739
Echinococcus granulosus Diacylglycerol kinase theta 0.0125 0.0027 0.0005
Brugia malayi ephrin receptor 1 precursor 0.0162 0.0174 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.1827 0.3083
Schistosoma mansoni protein kinase 0.0194 0.0298 0.0481
Loa Loa (eye worm) hypothetical protein 0.0217 0.0388 0.0386
Schistosoma mansoni protein kinase 0.0717 0.2337 0.3952
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0463 0.1346 0.14
Entamoeba histolytica protein kinase, putative 0.0176 0.0228 0.0213
Entamoeba histolytica hypothetical protein 0.0127 0.0035 0.0009
Loa Loa (eye worm) hypothetical protein 0.0463 0.1348 0.1401
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0315 0.0768 0.0827
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.052 0.1569 0.1636
Trichomonas vaginalis STE family protein kinase 0.0208 0.0354 0.0373
Echinococcus multilocularis tyrosine protein kinase 0.0354 0.0922 0.1301
Echinococcus multilocularis protein kinase c epsilon type 0.1297 0.4599 0.6621
Loa Loa (eye worm) hypothetical protein 0.0137 0.0074 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0142 0.0094 0.0076
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0163 0.0178 0.0226
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0265 0.0575 0.0585
Brugia malayi Protein kinase domain containing protein 0.0288 0.0665 0.0679
Leishmania major protein kinase, putative 0.0399 0.1096 0.2684
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0261 0.0561 0.0596
Loa Loa (eye worm) TK/KIN16 protein kinase 0.158 0.5702 0.6006
Loa Loa (eye worm) hypothetical protein 0.0293 0.0685 0.0701
Brugia malayi Protein kinase domain containing protein 0.0409 0.1136 0.1178
Plasmodium vivax protein kinase Crk2 0.0463 0.1346 0.2483
Schistosoma mansoni serine/threonine protein kinase 0.052 0.1569 0.2644
Echinococcus multilocularis oxysterol binding protein 9 0.0127 0.0035 0.0019
Brugia malayi Protein kinase domain containing protein 0.1152 0.4034 0.4242
Echinococcus multilocularis serine:threonine protein kinase 0.0268 0.0586 0.0815
Plasmodium vivax casein kinase 1, putative 0.026 0.0554 0.1013
Brugia malayi Variant SH3 domain containing protein 0.0222 0.0409 0.0408
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0208 0.0354 0.0332
Entamoeba histolytica hypothetical protein 0.0127 0.0035 0.0009
Echinococcus multilocularis tyrosine protein kinase Src42A 0.049 0.1453 0.207
Loa Loa (eye worm) hypothetical protein 0.0268 0.0586 0.0596
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.085 0.2857 0.2998
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0316 0.0511
Leishmania major casein kinase, putative 0.026 0.0554 0.1312
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0416 0.1164 0.1652
Loa Loa (eye worm) syntrophin-1 0.0131 0.0052 0.0031
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0599 0.1877 0.2683
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0482 0.1421 0.1479
Loa Loa (eye worm) TK protein kinase 0.0584 0.182 0.1901
Schistosoma mansoni neuroglian 0.0123 0.0022 0.0011
Brugia malayi Protein kinase domain containing protein 0.0199 0.0316 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Toxoplasma gondii AGC kinase 0.114 0.3987 0.4421
Brugia malayi Protein kinase domain containing protein 0.0803 0.2673 0.2803
Loa Loa (eye worm) AGC/PKA protein kinase 0.114 0.3987 0.4193
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0222 0.0405 0.0405
Echinococcus granulosus dual specificity 0.0394 0.1077 0.1057
Toxoplasma gondii AGC kinase 0.2422 0.8985 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.1502 0.5396 0.5386
Giardia lamblia Kinase, PLK 0.0599 0.1877 0.3326
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0408 0.1132 0.2776
Echinococcus granulosus epidermal growth factor receptor 0.0987 0.3391 0.3376
Entamoeba histolytica protein kinase, putative 0.1016 0.3504 0.3678
Loa Loa (eye worm) hypothetical protein 0.0251 0.0521 0.0527
Trypanosoma cruzi casein kinase II, putative 0.0525 0.1589 0.2654
Brugia malayi Protein kinase domain containing protein 0.0196 0.0306 0.03
Brugia malayi Protein kinase domain containing protein 0.0246 0.0499 0.0504
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0463 0.1346 0.3317
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0127 0.0035 0.0037
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0518 0.1561 0.1628
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1291 0.4574 0.4813
Plasmodium falciparum calcium-dependent protein kinase 2 0.0235 0.0458 0.0789
Brugia malayi cell division control protein 2 homolog 0.0463 0.1346 0.14
Loa Loa (eye worm) hypothetical protein 0.0298 0.0703 0.072
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0525 0.1589 0.2934
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Brugia malayi phosphoinositide-dependent protein kinase I 0.0199 0.0316 0.0311
Toxoplasma gondii AtPH1 family protein 0.0127 0.0035 0.0009
Leishmania major protein kinase, putative 0.0222 0.0409 0.0945
Schistosoma mansoni tyrosine kinase 0.0424 0.1194 0.2005
Echinococcus granulosus activated cdc42 kinase 1 0.0288 0.0664 0.0643
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0343 0.0557
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1406 0.5023 0.7233
Echinococcus multilocularis casein kinase I delta 0.026 0.0554 0.0769
Schistosoma mansoni serine/threonine protein kinase 0.114 0.3987 0.6761
Onchocerca volvulus 0.1204 0.4235 0.874
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1297 0.4599 0.484
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0164 0.018 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis TGF beta receptor type 1 0.0178 0.0235 0.0307
Echinococcus granulosus GRB2 associated binding protein 3 0.0127 0.0035 0.0013
Onchocerca volvulus 0.0217 0.0388 0.0733
Plasmodium falciparum casein kinase 2, alpha subunit 0.0525 0.1589 0.2898
Echinococcus granulosus tyrosine protein kinase Src42A 0.0322 0.0797 0.0776
Echinococcus multilocularis calcium activated potassium channel 0.0269 0.059 0.0821
Loa Loa (eye worm) hypothetical protein 0.0256 0.0538 0.0546
Loa Loa (eye worm) hypothetical protein 0.0133 0.0059 0.0038
Trypanosoma cruzi casein kinase, putative 0.026 0.0554 0.0886
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0887 0.3001 0.4309
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Plasmodium vivax tyrosine kinase-like protein, putative 0.0147 0.0115 0.0198
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0205 0.0342 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0222 0.0409 0.0638
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0205 0.0342 0.0525
Brugia malayi Immunoglobulin I-set domain containing protein 0.158 0.5702 0.6006
Echinococcus multilocularis twitchin 0.0153 0.0137 0.0166
Schistosoma mansoni dynamin 0.0127 0.0035 0.0033
Schistosoma mansoni diacylglycerol kinase theta 0.0125 0.0027 0.002
Trichomonas vaginalis STE family protein kinase 0.0208 0.0354 0.0373
Loa Loa (eye worm) hypothetical protein 0.0259 0.055 0.0558
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Echinococcus multilocularis mitogen activated protein kinase 0.0261 0.0561 0.0779
Trichomonas vaginalis protein transport protein sec7, putative 0.0127 0.0035 0.0037
Echinococcus multilocularis tyrosine protein kinase Src64B 0.049 0.1453 0.207
Schistosoma mansoni tyrosine kinase 0.027 0.0595 0.0985
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Echinococcus granulosus calcium dependent protein kinase 0.0139 0.0085 0.0062
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0206 0.0343 0.0779
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Trypanosoma brucei rac serine-threonine kinase, putative 0.2549 0.9479 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0937 0.3196 0.3357
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0243 0.0487 0.0492
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0527 0.1598 0.1579
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Schistosoma mansoni tyrosine kinase 0.0556 0.171 0.2885
Entamoeba histolytica hypothetical protein 0.0127 0.0035 0.0009
Loa Loa (eye worm) TK protein kinase 0.0422 0.1186 0.1231
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1406 0.5023 0.5012
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0278 0.0626 0.0605
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.1045 0.3614 0.5195
Brugia malayi serine/threonine kinase 12 0.0399 0.1096 0.1135
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.114 0.3987 0.675
Schistosoma mansoni serine/threonine protein kinase 0.054 0.1648 0.2778
Loa Loa (eye worm) AGC/NDR protein kinase 0.1016 0.3504 0.3682
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0094 0.0134
Plasmodium falciparum protein kinase 5 0.0463 0.1346 0.2445
Plasmodium falciparum calcium-dependent protein kinase 7 0.0222 0.0409 0.0697
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0222 0.0409 0.0669
Brugia malayi Dynamin 0.0127 0.0035 0.0014
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0222 0.0409 0.0669
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0127 0.0035 0.0009
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0409 0.1136 0.1178
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Echinococcus multilocularis myosin iiia 0.0205 0.0342 0.0463
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.1453 0.207
Echinococcus granulosus cyclin dependent kinase 5 0.0463 0.1346 0.1327
Trichomonas vaginalis centaurin/arf, putative 0.0127 0.0035 0.0037
Giardia lamblia Kinase, CAMK CAMKL 0.0215 0.0378 0.0483
Schistosoma mansoni protein kinase 0.0803 0.2673 0.4523
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0209 0.0356 0.0548
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0298 0.0703 0.1141
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0862 0.2902 0.4913
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0201 0.0324 0.0525
Trichomonas vaginalis CMGC family protein kinase 0.0408 0.1132 0.1195
Echinococcus granulosus tyrosine protein kinase ABL1 0.0654 0.2092 0.2074
Brugia malayi Casein kinase II, alpha chain 0.0525 0.1589 0.1657
Giardia lamblia Kinase, AGC AKT 0.037 0.0985 0.1634
Loa Loa (eye worm) hypothetical protein 0.0463 0.1348 0.1401
Echinococcus multilocularis tyrosine protein kinase Blk 0.0416 0.1164 0.1652
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0399 0.1096 0.1553
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0222 0.0409 0.0408
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0127 0.0035 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Brugia malayi Protein kinase domain containing protein 0.0127 0.0035 0.0014
Schistosoma mansoni tyrosine kinase 0.0987 0.3391 0.5745
Trichomonas vaginalis AGC family protein kinase 0.0399 0.1096 0.1156
Plasmodium falciparum calcium-dependent protein kinase 4 0.0235 0.0458 0.0789
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0171 0.0209 0.0187
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) TK/FAK protein kinase 0.0937 0.3194 0.3354
Echinococcus multilocularis raf serine:threonine protein kinase 0.0223 0.041 0.0561
Toxoplasma gondii Oxysterol-binding protein 0.0127 0.0035 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis calcium dependent secretion activator 1 0.0127 0.0035 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0356 0.0579
Schistosoma mansoni protein kinase 0.0208 0.0354 0.0575
Trichomonas vaginalis AGC family protein kinase 0.0199 0.0316 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Trypanosoma cruzi casein kinase, putative 0.026 0.0554 0.0886
Toxoplasma gondii CMGC kinase, CK2 family 0.0525 0.1589 0.1744
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0507 0.152 0.2536
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0527 0.1598 0.2279
Trichomonas vaginalis CMGC family protein kinase 0.0463 0.1346 0.142
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0399 0.1096 0.1131
Echinococcus multilocularis CDC7 cell division cycle 7 0.0156 0.0151 0.0186
Echinococcus granulosus growth factor receptor bound protein 2 0.0176 0.0227 0.0205
Schistosoma mansoni tyrosine kinase 0.0198 0.0314 0.0508
Echinococcus granulosus casein kinase I delta 0.026 0.0554 0.0533
Trypanosoma cruzi aurora B kinase, putative 0.0399 0.1096 0.1811
Brugia malayi Immunoglobulin I-set domain containing protein 0.0176 0.0228 0.0218
Schistosoma mansoni tyrosine kinase 0.0326 0.0812 0.1356
Schistosoma mansoni nephrin 0.0316 0.0772 0.1287
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0268 0.0586 0.0596
Schistosoma mansoni oxysterol-binding protein 1 0.0127 0.0035 0.0033
Leishmania major protein kinase, putative 0.0298 0.0703 0.169
Echinococcus multilocularis dual specificity 0.0209 0.0356 0.0482
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0127 0.0035 0.0009
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0208 0.0351 0.0348
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0222 0.0409 0.0638
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0862 0.2902 0.4165
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0075 0.0056
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2024 0.7431 0.7834
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0703 0.0742
Trichomonas vaginalis centaurin/arf, putative 0.0127 0.0035 0.0037
Onchocerca volvulus 0.0196 0.0306 0.0563
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0127 0.0035 0.0014
Echinococcus granulosus epidermal growth factor receptor 0.0692 0.224 0.2223
Echinococcus multilocularis 0.0272 0.0602 0.0838
Giardia lamblia Kinase, CMGC MAPK 0.0261 0.0561 0.0829
Loa Loa (eye worm) raf kinase 0.0125 0.0027 0.0005
Echinococcus multilocularis 0.0293 0.0682 0.0955
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.059 0.0977
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0298 0.0703 0.1141
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0394 0.1077 0.1779
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0235 0.0458 0.0461
Echinococcus multilocularis oxysterol binding protein 3 0.0127 0.0035 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0217 0.0388 0.0366
Echinococcus multilocularis dual specificity 0.0209 0.0356 0.0482
Trypanosoma cruzi cdc2-related kinase 3 0.0463 0.1346 0.2239
Echinococcus multilocularis casein kinase I alpha 0.026 0.0554 0.0769
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0788 0.2612 0.5363
Loa Loa (eye worm) hypothetical protein 0.0588 0.1833 0.1915
Brugia malayi Protein kinase domain containing protein 0.0357 0.0931 0.0961
Entamoeba histolytica protein kinase, putative 0.0394 0.1077 0.1111
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0259 0.055 0.0558
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0507 0.152 0.2536
Loa Loa (eye worm) hypothetical protein 0.0278 0.0626 0.0638
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.1453 0.207
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0273 0.0605 0.0616
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.0665 0.1105
Schistosoma mansoni serine/threonine protein kinase 0.114 0.3987 0.6761
Giardia lamblia Kinase, CMGC CDK 0.0463 0.1346 0.2319
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0235 0.0458 0.0437
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0137 0.0074 0.0052
Entamoeba histolytica cell division protein kinase 2, putative 0.0472 0.1381 0.1433
Loa Loa (eye worm) hypothetical protein 0.0235 0.0458 0.0461
Echinococcus multilocularis Rac GTPase activating protein 1 0.0125 0.0027 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Entamoeba histolytica protein kinase, putative 0.0408 0.1132 0.1169
Brugia malayi Protein kinase domain containing protein 0.0394 0.1077 0.1115
Brugia malayi serine/threonine-protein kinase 6 0.0399 0.1096 0.1135
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0235 0.0458 0.0631
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0707 0.2298 0.3291
Entamoeba histolytica protein kinase domain containing protein 0.0394 0.1077 0.1111
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0235 0.0458 0.0631
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.114 0.3987 0.4421
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0125 0.0027 0.0005
Echinococcus granulosus tyrosine protein kinase Src64B 0.049 0.1453 0.1434
Echinococcus multilocularis roundabout 2 0.0359 0.0939 0.1326
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0298 0.0703 0.1141
Echinococcus multilocularis nervana 2 0.1406 0.5023 0.7233
Schistosoma mansoni serine/threonine protein kinase 0.1016 0.3504 0.5938
Plasmodium falciparum casein kinase 1 0.026 0.0554 0.0967
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0862 0.2902 0.3045
Brugia malayi Protein kinase domain containing protein 0.0354 0.0922 0.0951
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Echinococcus granulosus twitchin 0.0388 0.1054 0.1034
Trichomonas vaginalis CK1 family protein kinase 0.026 0.0554 0.0584
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0196 0.0306 0.0295
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0803 0.2673 0.2657
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis c src tyrosine kinase 0.027 0.0595 0.0828
Trypanosoma brucei protein kinase, putative 0.027 0.0596 0.0594
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0256 0.0271
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0261 0.0561 0.0898
Schistosoma mansoni protein kinase 0.0399 0.1096 0.1839
Echinococcus granulosus casein kinase I alpha 0.026 0.0554 0.0533
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0222 0.0409 0.0638
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0208 0.0354 0.0332
Echinococcus multilocularis growth factor receptor bound protein 2 0.0172 0.0211 0.0274
Giardia lamblia Kinase, STE STE20 0.0265 0.0575 0.0857
Schistosoma mansoni tyrosine kinase 0.0594 0.1857 0.3134
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0887 0.3001 0.2985
Schistosoma mansoni tyrosine kinase 0.0692 0.224 0.3786
Echinococcus multilocularis hypothetical protein 0.0173 0.0216 0.0281
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0408 0.1132 0.1113
Brugia malayi Protein kinase domain containing protein 0.0236 0.046 0.0463
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0217 0.0388 0.0602
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0222 0.0409 0.0638
Echinococcus multilocularis Immunoglobulin 0.0235 0.0458 0.0631
Entamoeba histolytica hypothetical protein 0.0222 0.0409 0.0404
Echinococcus multilocularis N chimaerin 0.0222 0.0409 0.0559
Entamoeba histolytica protein kinase, putative 0.2549 0.9479 1
Loa Loa (eye worm) hypothetical protein 0.114 0.3987 0.4193
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0441 0.1261 0.1792
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0194 0.0296 0.0285
Brugia malayi RhoGAP domain containing protein 0.0222 0.0409 0.0408
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Echinococcus granulosus Rac GTPase activating protein 1 0.0125 0.0027 0.0005
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0127 0.0035 0.0051
Schistosoma mansoni hypothetical protein 0.0182 0.025 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.1544 0.2602
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0041 0.0019
Plasmodium falciparum NIMA related kinase 1 0.0315 0.0768 0.1367
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0228 0.043 0.0431
Schistosoma mansoni hypothetical protein 0.0217 0.0388 0.0633
Brugia malayi Variant SH3 domain containing protein 0.0172 0.0211 0.02
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0127 0.0035 0.0009
Echinococcus granulosus Immunoglobulin 0.0235 0.0458 0.0437
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.2422 0.8985 0.9478
Loa Loa (eye worm) rho-GTPase-activating 0.0127 0.0035 0.0014
Echinococcus multilocularis cyclin dependent kinase 1 0.0463 0.1346 0.1915
Echinococcus multilocularis serine:threonine protein kinase 38 0.1016 0.3504 0.5036
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0357 0.0931 0.0961
Trichomonas vaginalis AGC family protein kinase 0.114 0.3987 0.4207
Plasmodium falciparum serine/threonine protein kinase 0.0149 0.0123 0.0165
Leishmania major casein kinase II, putative 0.0525 0.1589 0.3932
Echinococcus multilocularis protein kinase shaggy 0.0408 0.1132 0.1606
Trichomonas vaginalis alpha chimerin, putative 0.0127 0.0035 0.0037
Leishmania major folate/biopterin transporter, putative 0.0222 0.0409 0.0945
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0151 0.0231
Schistosoma mansoni atypical protein kinase C 0.133 0.4725 0.8017
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Trypanosoma cruzi polo-like protein kinase, putative 0.0599 0.1877 0.3146
Loa Loa (eye worm) AGC/AKT protein kinase 0.2549 0.9479 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.114 0.3987 0.675
Brugia malayi diacylglycerol kinase 0.0125 0.0027 0.0005
Loa Loa (eye worm) hypothetical protein 0.0235 0.0458 0.0461
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.026 0.0554 0.0562
Brugia malayi protein unc-22 0.0176 0.0228 0.0218
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0599 0.1877 0.1961
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0142 0.0094 0.0076
Echinococcus multilocularis serine threonine protein kinase 0.1193 0.4194 0.6034
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0222 0.0409 0.0559
Schistosoma mansoni growth factor receptor-bound protein 0.0127 0.0035 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0399 0.1096 0.1131
Echinococcus multilocularis protein KINase family member (kin 25) 0.0171 0.0209 0.027
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0441 0.1261 0.1792
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0209 0.0356 0.0811
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0205 0.0342 0.0525
Brugia malayi Protein kinase domain containing protein 0.2024 0.7431 0.7834
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0127 0.0035 0.0009
Schistosoma mansoni tyrosine kinase 0.0594 0.1857 0.3134
Echinococcus multilocularis Immunoglobulin 0.0235 0.0458 0.0631
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0236 0.046 0.0439
Echinococcus granulosus protein tyrosine kinase 0.0927 0.3156 0.314
Echinococcus multilocularis dynamin 1 0.0127 0.0035 0.0019
Entamoeba histolytica protein kinase, putative 0.0243 0.049 0.0489
Entamoeba histolytica PH domain containing protein 0.0127 0.0035 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0703 0.117
Echinococcus granulosus protein kinase C gamma type 0.1193 0.4194 0.4181
Brugia malayi serine/threonine-protein kinase plk-2 0.0599 0.1877 0.1961
Schistosoma mansoni serine/threonine protein kinase 0.114 0.3987 0.6761
Echinococcus multilocularis 0.0202 0.033 0.0445
Brugia malayi casein kinase 1, delta 0.026 0.0554 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0343 0.0557
Loa Loa (eye worm) AUR protein kinase 0.0399 0.1096 0.1135
Brugia malayi hypothetical protein 0.0127 0.0035 0.0014
Echinococcus granulosus tyrosine protein kinase Src42A 0.049 0.1453 0.1434
Brugia malayi Tyrosine-protein kinase abl-1 0.0283 0.0644 0.0658
Echinococcus multilocularis protein kinase c iota type 0.1317 0.4675 0.673
Trypanosoma cruzi p21-activated kinase 3, putative 0.0142 0.0094 0.0101
Brugia malayi Protein kinase domain containing protein 0.0266 0.058 0.0589
Entamoeba histolytica protein kinase, putative 0.0162 0.0174 0.0156
Plasmodium falciparum calcium-dependent protein kinase 5 0.0235 0.0458 0.0789
Giardia lamblia Kinase, NEK 0.0315 0.0768 0.1223
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0236 0.046 0.0634
Loa Loa (eye worm) hypothetical protein 0.0308 0.0743 0.0762
Loa Loa (eye worm) AGC/PKN protein kinase 0.1303 0.462 0.4862
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) TK/INSR protein kinase 0.0864 0.291 0.3054
Echinococcus granulosus dual specificity 0.0209 0.0356 0.0334
Brugia malayi RhoGEF domain containing protein 0.0125 0.0027 0.0005
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0507 0.152 0.3756
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0137 0.0207
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.3974
Trichomonas vaginalis centaurin alpha, putative 0.0127 0.0035 0.0037
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Loa Loa (eye worm) TK protein kinase 0.0354 0.0922 0.0951
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0298 0.0703 0.0707
Loa Loa (eye worm) hypothetical protein 0.0463 0.1348 0.1401
Schistosoma mansoni serine/threonine protein kinase 0.0569 0.1761 0.2971
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0217 0.0388 0.0528
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0215 0.0378 0.0687
Trichomonas vaginalis AGC family protein kinase 0.0399 0.1096 0.1156
Echinococcus granulosus geminin 0.0182 0.025 0.0228
Echinococcus granulosus c src tyrosine kinase 0.027 0.0595 0.0574
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0127 0.0035 0.0013
Trichomonas vaginalis centaurin beta, putative 0.0127 0.0035 0.0037
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0199 0.0316 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.2612 0.442
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.1346 0.2265
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0222 0.0409 0.0638
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1291 0.4574 0.4562
Loa Loa (eye worm) AUR protein kinase 0.0399 0.1096 0.1135
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0333 0.084 0.1183
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0277 0.062 0.0633
Echinococcus granulosus protein kinase c iota type 0.1317 0.4675 0.4663
Brugia malayi Fibronectin type III domain containing protein 0.0259 0.055 0.0558
Trichomonas vaginalis AGC family protein kinase 0.0208 0.0351 0.0371
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0222 0.0409 0.0638
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0333 0.084 0.082
Entamoeba histolytica protein kinase, putative 0.0208 0.0354 0.0345
Loa Loa (eye worm) hypothetical protein 0.0311 0.0753 0.0773
Echinococcus granulosus cyclin dependent kinase 9 0.0147 0.0116 0.0094
Echinococcus granulosus nervana 2 0.1406 0.5023 0.5012
Brugia malayi Protein kinase domain containing protein 0.1038 0.3589 0.3772
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0176 0.0228 0.0206
Trichomonas vaginalis STE family protein kinase 0.0162 0.0174 0.0184
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0408 0.1132 0.1901
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.052 0.1569 0.155
Schistosoma mansoni serine/threonine kinase 0.1016 0.3504 0.5938
Echinococcus multilocularis activated cdc42 kinase 1 0.0288 0.0664 0.0928
Echinococcus multilocularis serine:threonine protein kinase 3 0.0571 0.1766 0.2522
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0463 0.1346 0.1472
Loa Loa (eye worm) cytohesin 3 0.0127 0.0035 0.0014
Loa Loa (eye worm) IKK protein kinase 0.1152 0.4034 0.4242
Echinococcus granulosus Oxysterol binding protein 11 0.0127 0.0035 0.0013
Brugia malayi probable spectrin beta chain 0.0127 0.0035 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0499 0.0822
Schistosoma mansoni zinc finger protein 0.0127 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Trichomonas vaginalis AGC family protein kinase 0.1165 0.4083 0.4307
Plasmodium falciparum cGMP-dependent protein kinase 0.0204 0.0338 0.0564
Brugia malayi hypothetical protein 0.0259 0.055 0.0558
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Brugia malayi Oxysterol-binding protein 0.0127 0.0035 0.0014
Brugia malayi Cam kinase protein 1 0.0235 0.0458 0.0461
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Echinococcus granulosus nervana 2 0.1406 0.5023 0.5012
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0703 0.117
Entamoeba histolytica hypothetical protein 0.0127 0.0035 0.0009
Echinococcus multilocularis aurora kinase A 0.0399 0.1096 0.1553
Loa Loa (eye worm) RasGEF domain-containing protein 0.0125 0.0027 0.0005
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0149 0.0123 0.0151
Schistosoma mansoni tyrosine kinase 0.0864 0.291 0.4927
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0149 0.0123 0.0108
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0692 0.224 0.2223
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.1261 0.212
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0208 0.0354 0.0479
Loa Loa (eye worm) TK/ROR protein kinase 0.0155 0.0147 0.0132
Giardia lamblia Kinase, CMGC GSK 0.0408 0.1132 0.1913
Plasmodium falciparum protein serine/threonine kinase-1 0.0298 0.0703 0.1246
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0298 0.0703 0.0755
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Onchocerca volvulus 0.0164 0.018 0.0302
Brugia malayi Protein kinase c protein 2 0.0397 0.109 0.1129
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0127 0.0035 0.0013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0261 0.0561 0.133
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0265 0.0575 0.0585
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Brugia malayi MH2 domain containing protein 0.0128 0.0041 0.0019
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.027 0.0595 0.0985
Echinococcus granulosus unc 13 munc13 0.0133 0.0059 0.0036
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0147 0.0115 0.0098
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0222 0.0409 0.0744
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0399 0.1096 0.1076
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0343 0.0557
Schistosoma mansoni diacylglycerol kinase theta 0.0125 0.0027 0.002
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0222 0.0409 0.0945
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0127 0.0035 0.0037
Schistosoma mansoni protein kinase C 0.0133 0.0059 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0235 0.0458 0.0631
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0803 0.2673 0.2803
Leishmania major protein kinase, putative 0.0235 0.0458 0.107
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0142 0.0094 0.0076
Brugia malayi Furin-like cysteine rich region family protein 0.0987 0.3391 0.3562
Echinococcus multilocularis geminin 0.0182 0.025 0.0329
Echinococcus multilocularis casein kinase ii subunit alpha 0.0525 0.1589 0.2267
Echinococcus multilocularis transfer RNA-Thr 0.0288 0.0664 0.0928
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0176 0.0228 0.0206
Loa Loa (eye worm) casein kinase 0.0192 0.0291 0.0284
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0277 0.062 0.06
Schistosoma mansoni serine/threonine protein kinase 0.1318 0.4679 0.7939
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0298 0.0287
Loa Loa (eye worm) Plekhf2 protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0131 0.0051 0.003
Entamoeba histolytica PH domain containing protein kinase, putative 0.1628 0.589 0.6203
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0149 0.0123 0.0107
Brugia malayi map kinase activated protein kinase protein 2 0.0862 0.2902 0.3045
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0527 0.1598 0.2279
Brugia malayi Protein kinase domain containing protein 0.0463 0.1346 0.14
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Trypanosoma brucei aurora B kinase 0.0399 0.1096 0.1123
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0463 0.1346 0.1327
Loa Loa (eye worm) hypothetical protein 0.0206 0.0343 0.0339
Echinococcus multilocularis insulin receptor 0.0864 0.291 0.4177
Echinococcus multilocularis PAK box P21 Rho binding 0.0162 0.0174 0.022
Loa Loa (eye worm) CAMK protein kinase 0.0176 0.0228 0.0218
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0127 0.0035 0.0014
Schistosoma mansoni protein kinase 0.0524 0.1584 0.2669
Leishmania major protein kinase, putative 0.0194 0.0298 0.0665
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0116 0.017
Brugia malayi Protein kinase domain containing protein 0.0701 0.2273 0.238
Entamoeba histolytica hypothetical protein 0.0394 0.1077 0.1111
Trypanosoma cruzi casein kinase, putative 0.026 0.0554 0.0886
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0235 0.0458 0.0835
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0235 0.0458 0.0461
Entamoeba histolytica protein kinase domain containing protein 0.0408 0.1132 0.1169
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0408 0.1132 0.1174
Schistosoma mansoni serine/threonine kinase 0.0366 0.0967 0.1619
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0293 0.0682 0.0698
Toxoplasma gondii protein kinase domain-containing protein 0.0222 0.0409 0.0426
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0235 0.0458 0.0835
Trichomonas vaginalis AGC family protein kinase 0.1038 0.3589 0.3786
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0204 0.0338 0.0347
Brugia malayi Cadps2 protein 0.0127 0.0035 0.0014
Brugia malayi SH2 domain containing protein 0.0196 0.0306 0.03
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0463 0.1346 0.3317
Schistosoma mansoni hypothetical protein 0.0127 0.0035 0.0033
Trypanosoma cruzi casein kinase, delta isoform, putative 0.026 0.0554 0.0886
Giardia lamblia Kinase, CK1 Casein kinase 0.026 0.0554 0.0816
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0514 0.1544 0.161
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0222 0.0409 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0228 0.0362
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Brugia malayi protein kinase C3,putative 0.0396 0.1086 0.1125
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0514 0.1544 0.1526
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0219 0.0396 0.0395
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0298 0.0703 0.072
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0261 0.0561 0.0557
Echinococcus multilocularis NCK adaptor protein 0.0176 0.0227 0.0296
Trichomonas vaginalis STE family protein kinase 0.0208 0.0354 0.0373
Trichomonas vaginalis hypothetical protein 0.0127 0.0035 0.0037
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0206 0.0343 0.0326
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0127 0.0035 0.0051
Schistosoma mansoni oxysterol-binding protein 1 0.0127 0.0035 0.0033
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0235 0.0458 0.0481
Echinococcus multilocularis mitogen activated protein kinase 11 0.0507 0.152 0.2166
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0313 0.0761 0.1069
Schistosoma mansoni syntrophin 0.0131 0.0052 0.0062
Schistosoma mansoni tyrosine kinase 0.0165 0.0184 0.0286
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0127 0.0035 0.0037
Giardia lamblia Kinase, CAMK CAMKL 0.0215 0.0378 0.0483
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0452 0.1302 0.1283
Toxoplasma gondii hypothetical protein 0.0127 0.0035 0.0009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0235 0.0458 0.0437
Onchocerca volvulus 0.0176 0.0228 0.0402
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0261 0.0561 0.0898
Trypanosoma brucei casein kinase I, isoform 2 0.026 0.0554 0.0549
Entamoeba histolytica protein kinase, putative 0.2549 0.9479 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0235 0.0458 0.0835
Echinococcus granulosus cyclin dependent kinase 1 0.0463 0.1346 0.1327
Toxoplasma gondii phosphatidylinositol transfer protein 0.0127 0.0035 0.0009
Schistosoma mansoni dynamin 0.0127 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0155 0.0147 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Schistosoma mansoni serine/threonine protein kinase 0.1016 0.3504 0.5938
Schistosoma mansoni tyrosine kinase 0.0692 0.224 0.3786
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Brugia malayi Pleckstrin Homology Domain 0.0251 0.0521 0.0527
Plasmodium falciparum protein kinase, putative 0.0194 0.0298 0.049
Giardia lamblia Kinase, CMGC CDK 0.0463 0.1346 0.2319
Schistosoma mansoni myotubularin-related protein 0.0127 0.0035 0.0033
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0178 0.0235 0.0307
Echinococcus multilocularis cyclin dependent kinase 0.0463 0.1346 0.1915
Trypanosoma brucei cdc2-related kinase 3 0.0463 0.1346 0.1388
Entamoeba histolytica p21-activated kinase 0.0335 0.0847 0.0868
Echinococcus granulosus TGF-beta receptor type-1 0.0178 0.0235 0.0213
Loa Loa (eye worm) hypothetical protein 0.0252 0.0525 0.0532
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0147 0.0115 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Echinococcus granulosus dynamin 1 0.0127 0.0035 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0408 0.1132 0.1195
Brugia malayi Variant SH3 domain containing protein 0.0131 0.0051 0.003
Brugia malayi serine/threonine-protein kinase PAK 7 0.0518 0.1561 0.1628
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0343 0.0557
Echinococcus granulosus dual specificity 0.0209 0.0356 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.1303 0.462 0.7838
Toxoplasma gondii histone kinase SNF1, putative 0.0206 0.0343 0.0353
Echinococcus granulosus NDR protein kinase 0.1016 0.3504 0.3489
Schistosoma mansoni tyrosine kinase 0.0637 0.2024 0.3419
Leishmania major protein kinase, putative 0.0205 0.0342 0.0777
Brugia malayi Protein kinase domain 0.0208 0.0354 0.035
Trypanosoma cruzi casein kinase, putative 0.026 0.0554 0.0886
Plasmodium falciparum serine/threonine protein kinase KIN 0.0206 0.0343 0.0574
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.1502 0.5396 1
Echinococcus granulosus titin 0.0176 0.0228 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.1261 0.212
Entamoeba histolytica protein kinase, putative 0.0222 0.0409 0.0404
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Loa Loa (eye worm) gastrulation defective protein 1 0.015 0.0125 0.0109
Schistosoma mansoni kinase 0.0638 0.203 0.3428
Entamoeba histolytica protein kinase, putative 0.0209 0.0356 0.0348
Plasmodium vivax PH domain containing protein 0.0127 0.0035 0.0051
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.1016 0.3504 0.5036
Onchocerca volvulus 0.0433 0.1229 0.2485
Echinococcus multilocularis cyclin dependent kinase 19 0.0246 0.0499 0.0689
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0208 0.0354 0.0332
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0707 0.2298 0.228
Brugia malayi protein kinase C II. 0.1297 0.4599 0.484
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0497 0.1479 0.3652
Brugia malayi Temporarily assigned gene name protein 59 0.0217 0.0388 0.0386
Schistosoma mansoni protein kinase C mu 0.0125 0.0027 0.002
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0507 0.152 0.1584
Echinococcus multilocularis mitogen activated protein kinase 3 0.0261 0.0561 0.0779
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.114 0.3987 0.675
Trichomonas vaginalis CK1 family protein kinase 0.026 0.0554 0.0584
Leishmania major protein kinase A catalytic subunit 0.114 0.3987 1
Trypanosoma brucei SNF1-related protein kinases, putative 0.0206 0.0343 0.0326
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0228 0.043 0.059
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0261 0.0561 0.133
Brugia malayi P38 map kinase family protein 2 0.0507 0.152 0.1584
Entamoeba histolytica protein kinase, putative 0.0235 0.0458 0.0456
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0408 0.1132 0.1174
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0163 0.0178 0.0165
Echinococcus multilocularis Pleckstrin y 0.0137 0.0074 0.0074
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0788 0.2612 0.2739
Schistosoma mansoni unc-13 (munc13) 0.0133 0.0059 0.0073
Brugia malayi Oxysterol binding protein 0.0127 0.0035 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Echinococcus granulosus expressed protein 0.0149 0.0123 0.0101
Echinococcus granulosus activin receptor type 0.0613 0.193 0.1912
Echinococcus multilocularis casein kinase I alpha 0.026 0.0554 0.0769
Schistosoma mansoni rho gtpase activating protein 0.0127 0.0035 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0217 0.0388 0.0602
Brugia malayi TBC domain containing protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0259 0.055 0.0558
Brugia malayi Protein kinase domain containing protein 0.0149 0.0123 0.0107
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Plasmodium vivax serine/threonine kinase-1, putative 0.0298 0.0703 0.129
Loa Loa (eye worm) hypothetical protein 0.0288 0.0664 0.0678
Loa Loa (eye worm) oxysterol binding protein 0.0127 0.0035 0.0014
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0408 0.1132 0.1234
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0127 0.0035 0.0009
Trypanosoma cruzi Protein kinase B 0.1628 0.589 1
Entamoeba histolytica protein kinase , putative 0.0399 0.1096 0.1131
Loa Loa (eye worm) hypothetical protein 0.148 0.531 0.5591
Toxoplasma gondii casein kinase I 0.026 0.0554 0.0588
Giardia lamblia Kinase, CMGC CK2 0.0525 0.1589 0.278
Onchocerca volvulus 0.0715 0.2331 0.4777
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.1038 0.3589 0.3772
Brugia malayi Syntrophin-1 0.0131 0.0052 0.0031
Brugia malayi C1-like domain containing protein 0.0529 0.1603 0.1671
Echinococcus granulosus serine:threonine protein kinase N2 0.0244 0.0493 0.0472
Echinococcus multilocularis casein kinase I delta 0.026 0.0554 0.0769
Echinococcus granulosus roundabout 2 0.0359 0.0939 0.0919
Brugia malayi Dynamin 0.0127 0.0035 0.0014
Brugia malayi Protein kinase domain containing protein 0.0156 0.0151 0.0136
Entamoeba histolytica casein kinase, putative 0.0525 0.1589 0.1653
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0169 0.02 0.0257
Echinococcus multilocularis titin 0.0176 0.0228 0.0298
Loa Loa (eye worm) hypothetical protein 0.0235 0.0458 0.0461
Brugia malayi Protein kinase domain containing protein 0.0473 0.1384 0.144
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0205 0.0342 0.0334
Echinococcus granulosus casein kinase I gamma 0.0288 0.0665 0.0644
Echinococcus granulosus defective proboscis extension response 0.0235 0.0458 0.0437
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0041 0.0019
Schistosoma mansoni protein kinase 0.0717 0.2337 0.3952
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1628 0.589 1
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0524 0.1584 0.1565
Brugia malayi hypothetical protein 0.0217 0.0388 0.0386
Schistosoma mansoni vam6/vps39 related 0.0217 0.0388 0.0633
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0149 0.0123 0.0223
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0205 0.0342 0.0334
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.5736
Echinococcus multilocularis calcium dependent protein kinase 0.0139 0.0085 0.009
Trypanosoma cruzi polo-like protein kinase, putative 0.0599 0.1877 0.3146
Onchocerca volvulus 0.0408 0.1132 0.2284
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.5736
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Trichomonas vaginalis AGC family protein kinase 0.0199 0.0316 0.0333
Trypanosoma cruzi NIMA-related kinase, putative 0.0222 0.0409 0.0638
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0265 0.0575 0.0923
Echinococcus multilocularis tyrosine kinase 0.0196 0.0306 0.041
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0183 0.0256 0.0339
Schistosoma mansoni tyrosine kinase 0.0527 0.1598 0.2693
Brugia malayi Immunoglobulin I-set domain containing protein 0.0584 0.182 0.1901
Trichomonas vaginalis CMGC family protein kinase 0.0463 0.1346 0.142
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0356 0.0375
Echinococcus granulosus cGMP dependent protein kinase 0.0204 0.0338 0.0316
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0259 0.055 0.0558
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0463 0.1346 0.14
Entamoeba histolytica protein kinase, putative 0.0399 0.1096 0.1131
Schistosoma mansoni serine/threonine protein kinase 0.1318 0.4679 0.7939
Echinococcus multilocularis tyrosine protein kinase shark 0.0424 0.1194 0.1695
Onchocerca volvulus 0.056 0.1723 0.3512
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0244 0.0494 0.0521
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.049 0.1453 0.1434
Echinococcus granulosus insulin receptor 0.0864 0.291 0.2894
Plasmodium falciparum calcium-dependent protein kinase 3 0.0235 0.0458 0.0789
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0441 0.1261 0.1241
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0265 0.0575 0.0572
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0561 0.0592
Brugia malayi SRC-1 0.049 0.1453 0.1513
Echinococcus multilocularis protein tyrosine kinase 0.0927 0.3156 0.4533
Echinococcus multilocularis cyclin dependent kinase 1 0.0463 0.1346 0.1915
Echinococcus granulosus protein kinase c epsilon type 0.1297 0.4599 0.4587
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Schistosoma mansoni hypothetical protein 0.0127 0.0035 0.0033
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0265 0.0575 0.1367
Entamoeba histolytica protein kinase, putative 0.0222 0.0409 0.0404
Trichomonas vaginalis AGC family protein kinase 0.1025 0.3539 0.3734
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.052 0.1569 0.2237
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0561 0.0592
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Schistosoma mansoni tyrosine kinase 0.0594 0.1857 0.3134
Loa Loa (eye worm) TK/EGFR protein kinase 0.0987 0.3391 0.3562
Leishmania major serine/threonine-protein kinase a, putative 0.0222 0.0409 0.0945
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.1453 0.1434
Brugia malayi probable protein kinase 0.051 0.1528 0.1593
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0236 0.046 0.0463
Echinococcus granulosus serine:threonine kinase SAD 1 0.0206 0.0343 0.0321
Loa Loa (eye worm) TK/EPH protein kinase 0.0271 0.0599 0.061
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0298 0.0703 0.1141
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0235 0.0458 0.0437
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0717 0.2337 0.232
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.1453 0.1434
Loa Loa (eye worm) hypothetical protein 0.0701 0.2273 0.238
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0788 0.2612 0.2596
Schistosoma mansoni protein kinase 0.0265 0.0575 0.0953
Brugia malayi Plekhf2 protein 0.0127 0.0035 0.0014
Schistosoma mansoni cell adhesion molecule 0.0123 0.0022 0.0011
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Schistosoma mansoni protein kinase 0.0525 0.1589 0.2678
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Echinococcus multilocularis serine:threonine protein kinase N2 0.0286 0.0658 0.0919
Echinococcus granulosus casein kinase I alpha 0.026 0.0554 0.0533
Trichomonas vaginalis CAMK family protein kinase 0.0599 0.1877 0.198
Entamoeba histolytica protein kinase, putative 0.0149 0.0123 0.0102
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0127 0.0035 0.0051
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0206 0.0343 0.0526
Schistosoma mansoni tyrosine kinase 0.0171 0.0209 0.0329
Brugia malayi serine/threonine protein kinase 6 0.0399 0.1096 0.1135
Echinococcus multilocularis tyrosine protein kinase HCK 0.0318 0.0783 0.1101
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0343 0.0362
Brugia malayi Protein kinase domain containing protein 0.0268 0.0586 0.0596
Trichomonas vaginalis CK1 family protein kinase 0.026 0.0554 0.0584
Trypanosoma brucei protein kinase, putative 0.0194 0.0298 0.0278
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Trichomonas vaginalis CMGC family protein kinase 0.0463 0.1346 0.142
Echinococcus multilocularis RNA directed DNA polymerase 0.0169 0.02 0.0257
Onchocerca volvulus 0.0174 0.022 0.0385
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0127 0.0035 0.0013
Echinococcus granulosus tyrosine protein kinase HCK 0.0318 0.0783 0.0763
Schistosoma mansoni protein kinase 0.0293 0.0682 0.1135
Entamoeba histolytica serine/threonine protein kinase, putative 0.0599 0.1877 0.1957
Brugia malayi Protein kinase domain containing protein 0.0196 0.0306 0.03
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0222 0.0409 0.0426
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.1016 0.3504 0.3489
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0394 0.1077 0.2636
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0473 0.0778
Echinococcus multilocularis dual specificity mitogen activated protein 0.0265 0.0575 0.08
Giardia lamblia Kinase, AGC PKA 0.114 0.3987 0.7328
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0222 0.0409 0.0638
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0701 0.2273 0.238
Echinococcus granulosus Glutaredoxin protein 5 0.1406 0.5023 0.5012
Echinococcus multilocularis Ras associated and pleckstrin y 0.0127 0.0035 0.0019
Echinococcus granulosus casein kinase i 0.026 0.0554 0.0533
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.1016 0.3504 0.5036
Loa Loa (eye worm) hypothetical protein 0.0196 0.0306 0.03
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0222 0.0409 0.0387
Echinococcus multilocularis death associated protein kinase 1 0.1897 0.6935 1
Echinococcus multilocularis casein kinase I alpha 0.026 0.0554 0.0769
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.062 0.1029
Echinococcus multilocularis DCC interacting protein 13 beta 0.0127 0.0035 0.0019
Echinococcus granulosus N chimaerin 0.0222 0.0409 0.0387
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0142 0.0094 0.0101
Echinococcus granulosus RNA directed DNA polymerase 0.0169 0.02 0.0178
Entamoeba histolytica PH domain containing protein kinase, putative 0.0371 0.0987 0.1015
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.049 0.1453 0.207
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0206 0.0343 0.0339
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0217 0.0388 0.0373
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0788 0.2612 0.3746
Echinococcus granulosus calcium dependent secretion activator 1 0.0127 0.0035 0.0013
Entamoeba histolytica casein kinase, putative 0.026 0.0554 0.0557
Entamoeba histolytica protein kinase domain containing protein 0.0408 0.1132 0.1169
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0571 0.1766 0.1844
Echinococcus granulosus protein kinase 0.0293 0.0682 0.0661
Entamoeba histolytica protein kinase, putative 0.0318 0.0783 0.08
Brugia malayi Protein kinase domain containing protein 0.2549 0.9479 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.052 0.1567 0.1549
Echinococcus granulosus serine:threonine protein kinase 0.0268 0.0586 0.0565
Schistosoma mansoni protein kinase 0.0178 0.0235 0.0373
Echinococcus multilocularis protein kinase c eta type 0.0125 0.0027 0.0007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.1453 0.207
Loa Loa (eye worm) hypothetical protein 0.0169 0.02 0.0188
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0209 0.0356 0.0353
Schistosoma mansoni kinase 0.0147 0.0116 0.017
Echinococcus multilocularis dual specificity 0.0209 0.0356 0.0482
Schistosoma mansoni tyrosine kinase 0.0864 0.291 0.4927
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0554 0.0916
Brugia malayi ribosomal protein S6 kinase alpha 3 0.037 0.0985 0.1018
Trichomonas vaginalis STE family protein kinase 0.0265 0.0575 0.0607
Loa Loa (eye worm) hypothetical protein 0.0236 0.0462 0.0465
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0217 0.0388 0.0633
Entamoeba histolytica serine/threonine protein kinase, putative 0.0206 0.0343 0.0334
Trichomonas vaginalis AGC family protein kinase 0.2549 0.9479 1
Loa Loa (eye worm) CDC7 protein kinase 0.0156 0.0151 0.0136
Echinococcus granulosus casein kinase ii subunit alpha 0.0525 0.1589 0.157
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0599 0.1877 0.1859
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0338 0.0548
Schistosoma mansoni serine/threonine-protein kinase 0.1628 0.589 1
Schistosoma mansoni tyrosine kinase 0.049 0.1453 0.2447
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0127 0.0035 0.0033
Schistosoma mansoni nephrin 0.0123 0.0022 0.0011
Schistosoma mansoni tyrosine kinase 0.0927 0.3156 0.5345
Loa Loa (eye worm) hypothetical protein 0.0125 0.0027 0.0005
Echinococcus multilocularis cyclin dependent kinase 5 0.0463 0.1346 0.1915
Leishmania major protein kinase, putative 0.0298 0.0703 0.169
Echinococcus multilocularis tyrosine protein kinase Abl 0.0445 0.1277 0.1816
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Echinococcus multilocularis casein kinase i 0.026 0.0554 0.0769
Echinococcus multilocularis casein kinase I gamma 0.0288 0.0665 0.0929
Trichomonas vaginalis kinesin light chain, putative 0.0127 0.0035 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.1291 0.4574 0.7759
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0277 0.062 0.0865
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.1346 0.2265
Echinococcus multilocularis dual specificity protein kinase clk2 0.0298 0.0703 0.0985
Schistosoma mansoni titin 0.0176 0.0228 0.0362
Onchocerca volvulus 0.0156 0.0151 0.0241
Echinococcus multilocularis expressed protein 0.0149 0.0123 0.0146
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0788 0.2612 0.2739
Loa Loa (eye worm) hypothetical protein 0.0492 0.146 0.152
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0127 0.0035 0.0014
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0235 0.0458 0.0481
Schistosoma mansoni cell adhesion molecule 0.0302 0.0717 0.1194
Schistosoma mansoni protein kinase 0.0208 0.0354 0.0575
Echinococcus multilocularis rho associated protein kinase 0.0715 0.2331 0.3339
Echinococcus multilocularis mitogen activated protein kinase 14 0.0507 0.152 0.2166
Giardia lamblia Aurora kinase 0.0399 0.1096 0.1844
Onchocerca volvulus Serine\/threonine kinase homolog 0.0599 0.1877 0.3833
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0494 0.0521
Entamoeba histolytica protein kinase, putative 0.0289 0.0668 0.0678
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0172 0.0211 0.0333
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0222 0.0409 0.0396
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0142 0.0094 0.0099
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.1045 0.3614 0.36
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0201 0.0324 0.0302
Entamoeba histolytica protein kinase domain containing protein 0.0209 0.0356 0.0348
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0561 0.0592
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0246 0.0499 0.0504
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0394 0.1077 0.1779
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0529 0.1603 0.1671
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0256 0.0271
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1393 0.4971 0.5233
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0235 0.0458 0.0631
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0416 0.1164 0.1145
Loa Loa (eye worm) TK/FER protein kinase 0.052 0.1567 0.1634
Onchocerca volvulus 0.0196 0.0306 0.0563
Echinococcus granulosus pdz domain containing protein 0.0148 0.0119 0.0097
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.026 0.0554 0.0562
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0235 0.0458 0.0481
Trichomonas vaginalis protein transport protein sec7, putative 0.0127 0.0035 0.0037
Brugia malayi Protein kinase domain containing protein 0.0163 0.0178 0.0165
Brugia malayi Protein kinase domain containing protein 0.0539 0.1643 0.1714
Loa Loa (eye worm) hypothetical protein 0.0414 0.1155 0.1198
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0643 0.2049 0.2144
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0228 0.043 0.0431
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0243 0.0487 0.0492
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0127 0.0035 0.0009
Echinococcus granulosus dual specificity mitogen activated protein 0.0265 0.0575 0.0554
Echinococcus granulosus serine threonine protein kinase nrc 0.1502 0.5396 0.5386
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.0224 0.0417 0.0417
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.059 0.0977
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0127 0.0035 0.0019
Loa Loa (eye worm) thyroid receptor interactor 0.0237 0.0465 0.0468
Brugia malayi Variant SH3 domain containing protein 0.0172 0.0211 0.02
Plasmodium vivax glycogen synthase kinase 3, putative 0.0408 0.1132 0.2087
Trypanosoma brucei cdc2-related kinase 1 0.0463 0.1346 0.1388
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0206 0.0343 0.0779
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.049 0.1453 0.207
Echinococcus granulosus activated cdc42 kinase 1 0.0288 0.0664 0.0643
Giardia lamblia Kinase, CMGC GSK 0.0408 0.1132 0.1913
Echinococcus granulosus cyclin dependent kinase 9 0.0156 0.0151 0.0129
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0151 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0561 0.0928
Loa Loa (eye worm) SRC-1 0.049 0.1453 0.1513
Echinococcus granulosus mitogen activated protein kinase 11 0.0507 0.152 0.1501
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0155 0.0147 0.0125
Schistosoma mansoni protein kinase 0.026 0.0554 0.0916
Brugia malayi Uncoordinated protein 104 0.0127 0.0035 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0268 0.0586 0.0618
Echinococcus granulosus oxysterol binding protein 9 0.0127 0.0035 0.0013
Brugia malayi PH domain containing protein 0.0127 0.0035 0.0014
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0701 0.2273 0.238
Echinococcus granulosus cytohesin 1 0.0127 0.0035 0.0013
Leishmania major protein kinase, putative 0.0222 0.0409 0.0945
Echinococcus multilocularis c Jun NH2 terminal kinase 0.085 0.2857 0.4101
Echinococcus granulosus cGMP dependent protein kinase 1 0.0204 0.0338 0.0316
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.049 0.1453 0.1434
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0035 0.0037
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0277 0.062 0.0633
Trypanosoma brucei Casein kinase II 0.0525 0.1589 0.1645
Loa Loa (eye worm) hypothetical protein 0.0171 0.0209 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0687 0.0725
Onchocerca volvulus 0.0136 0.0071 0.0074
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0127 0.0035 0.0019
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0244 0.0494 0.0521
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0176 0.0228 0.0218
Echinococcus granulosus myotubularin protein 13 0.0251 0.0521 0.05
Entamoeba histolytica protein kinase, putative 0.0176 0.0228 0.0213
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0235 0.0458 0.0448
Echinococcus multilocularis myotubularin protein 13 0.0251 0.0521 0.0721
Echinococcus multilocularis unc 13 (munc13) 0.0133 0.0059 0.0053
Brugia malayi Temporarily assigned gene name protein 59 0.0274 0.0608 0.0619
Entamoeba histolytica cell division protein kinase 2, putative 0.0463 0.1346 0.1395
Schistosoma mansoni rac gtpase activating protein 0.0125 0.0027 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.059 0.0977
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0094 0.0134
Trypanosoma cruzi cdc2-related kinase 1 0.0463 0.1346 0.2239
Schistosoma mansoni protein kinase 0.0524 0.1584 0.2669
Echinococcus multilocularis expressed conserved protein 0.0204 0.0338 0.0456
Loa Loa (eye worm) hypothetical protein 0.0421 0.1184 0.1229
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.062 0.0628
Echinococcus multilocularis ephrin type A receptor 4 A 0.0234 0.0454 0.0624
Loa Loa (eye worm) hypothetical protein 0.0127 0.0035 0.0014
Entamoeba histolytica PH domain containing protein 0.0127 0.0035 0.0009
Loa Loa (eye worm) hypothetical protein 0.056 0.1723 0.1798
Echinococcus multilocularis actin binding protein anillin 0.0127 0.0035 0.0019
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0194 0.0298 0.0449
Echinococcus granulosus mitogen activated protein kinase 3 0.0261 0.0561 0.054
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0399 0.1096 0.1131
Schistosoma mansoni adapter molecule crk 0.0172 0.0211 0.0333
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0075 0.0056
Echinococcus granulosus Pleckstrin y 0.0127 0.0035 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0357 0.0931 0.0983
Echinococcus granulosus CDC7 cell division cycle 7 0.0156 0.0151 0.0129
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0507 0.152 0.1572
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0127 0.0035 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0525 0.1589 0.1653
Brugia malayi Ras association domain family 1 isoform A 0.0125 0.0027 0.0005
Loa Loa (eye worm) hypothetical protein 0.0335 0.0848 0.0873
Schistosoma mansoni centaurin alpha 0.0127 0.0035 0.0033
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.052 0.1567 0.2235
Echinococcus granulosus aurora kinase A 0.0399 0.1096 0.1076
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0208 0.0354 0.0479
Echinococcus granulosus cyclin dependent kinase 19 0.0246 0.0499 0.0478
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0127 0.0035 0.0037
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.114 0.3987 0.5736
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0235 0.0458 0.0754
Trypanosoma cruzi cdc2-related kinase 1 0.0463 0.1346 0.2239
Trypanosoma cruzi cdc2-related kinase 3 0.0463 0.1346 0.2239
Echinococcus granulosus ephrin type A receptor 4 A 0.0234 0.0454 0.0433
Echinococcus multilocularis cyclin dependent kinase 9 0.0147 0.0116 0.0135
Trichomonas vaginalis STE family protein kinase 0.0265 0.0575 0.0607
Giardia lamblia Kinase, CMGC CLK 0.0298 0.0703 0.1099
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0127 0.0035 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0525 0.1589 0.1676
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0127 0.0035 0.0019
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0404 0.1117 0.1157
Brugia malayi Protein kinase domain containing protein 0.0166 0.0188 0.0175
Loa Loa (eye worm) hypothetical protein 0.0173 0.0216 0.0205
Loa Loa (eye worm) TK/FER protein kinase 0.0196 0.0306 0.03
Brugia malayi casein kinase I 0.026 0.0554 0.0562
Brugia malayi Doublecortin family protein 0.0222 0.0405 0.0405
Echinococcus granulosus protein kinase c eta type 0.0125 0.0027 0.0005
Echinococcus granulosus Pleckstrin y 0.0137 0.0074 0.0052
Echinococcus multilocularis nervana 2 0.1406 0.5023 0.7233
Entamoeba histolytica PH domain containing protein kinase, putative 0.1628 0.589 0.6203
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.114 0.3987 0.7385
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0166 0.0188 0.0175
Echinococcus granulosus serine:threonine protein kinase N2 0.0286 0.0658 0.0637
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0149 0.0123 0.0093

Activities

Activity type Activity value Assay description Source Reference
Lowering (functional) = 25 % Mean maximum percent lowering of glucose at a single dose of 10 mg/kg, subcutaneously using rat oral glucose tolerance test. ChEMBL. 8496927

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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