Detailed information for compound 924140

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 263.334 | Formula: C18H17NO
  • H donors: 0 H acceptors: 0 LogP: 3.65 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1Cc2ccccc2C(C1)c1cccc2c1cco2
  • InChi: 1S/C18H17NO/c1-19-11-13-5-2-3-6-14(13)17(12-19)15-7-4-8-18-16(15)9-10-20-18/h2-10,17H,11-12H2,1H3
  • InChiKey: CZRBQWFOPMBTQM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 4 Starlite/ChEMBL References
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 2 Starlite/ChEMBL References
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 3 620 aa 579 aa 33.2 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 4 630 aa 574 aa 31.5 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 2 617 aa 638 aa 32.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0364 0.0364
Echinococcus granulosus tubulin subunit TubB 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0292 0.2632 0.2632
Loa Loa (eye worm) animal heme peroxidase 0.0143 0.1241 0.1241
Brugia malayi hypothetical protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0298 0.0298
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0017 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.0038 0.0038
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0027 0.0027
Echinococcus granulosus carbonic anhydrase 0.0328 0.2965 0.2965
Loa Loa (eye worm) helicase 0.0011 0.0004 0.0004
Plasmodium falciparum glutathione reductase 0.0093 0.0775 0.0775
Mycobacterium ulcerans hypothetical protein 0.0024 0.0123 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0046
Echinococcus multilocularis NCK adaptor protein 0.002 0.0082 0.0082
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Onchocerca volvulus Peroxidasin homolog 0.0146 0.1269 0.2692
Toxoplasma gondii beta-1 tubulin, putative 0.1079 1 1
Echinococcus granulosus Tubulin beta 2C chain 0.1079 1 1
Brugia malayi tubulin alpha chain - mouse 0.0812 0.7498 0.7498
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.012 0.012
Schistosoma mansoni polycystin 1-related 0.0019 0.0081 0.0081
Echinococcus granulosus intersectin 2 0.0014 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus notch 0.0034 0.0216 0.0216
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0062 0.048 0.048
Brugia malayi Cadherin domain containing protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0049 0.0049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0258 0.0258
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Giardia lamblia NADPH oxidoreductase, putative 0.0241 0.2156 0.2091
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Onchocerca volvulus 0.0015 0.0036 0.0068
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) Notch2 0.0034 0.0216 0.0216
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0123 0.0123
Echinococcus granulosus transient receptor potential cation channel 0.0323 0.2927 0.2927
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0097 0.0097
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0534 0.0534
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0024 0.0126 0.0126
Schistosoma mansoni tubulin subunit beta 0.026 0.2332 0.2332
Brugia malayi hypothetical protein 0.0019 0.0081 0.0081
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0177 0.0177
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0328 0.2965 0.2965
Trichomonas vaginalis guanylate cyclase, putative 0.0062 0.048 0.048
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0364 0.0364
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0364 0.0364
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0327 0.0327
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0231 0.0231
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0538 0.0538
Onchocerca volvulus 0.0035 0.0231 0.0482
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0231 0.0231
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Schistosoma mansoni tyrosine kinase 0.0024 0.0126 0.0126
Echinococcus multilocularis protein jagged 1 0.0034 0.0216 0.0216
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0203 0.0203
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Brugia malayi Protein kinase domain containing protein 0.0052 0.0388 0.0388
Trypanosoma cruzi tubulin delta chain 0.026 0.2332 0.2319
Echinococcus granulosus microtubule associated protein 2 0.0694 0.6397 0.6397
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0097 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0263 0.0263
Schistosoma mansoni zinc finger protein 0.0014 0.0031 0.0031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0081 0.0081
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0203
Brugia malayi steroid hormone receptor 0.003 0.0177 0.0177
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Echinococcus multilocularis GPCR, family 2 0.0031 0.0193 0.0193
Echinococcus granulosus tubulin gamma 1 chain 0.0591 0.5425 0.5425
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0037 0.0037
Schistosoma mansoni tyrosine kinase 0.0054 0.0403 0.0403
Brugia malayi tailless protein 0.0014 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Mycobacterium ulcerans hypothetical protein 0.0035 0.0231 0.0642
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0097 0.0097
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0097 0.0097
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.024 0.024
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0024 0.0123 0.0123
Schistosoma mansoni multidrug resistance protein 0.0021 0.0097 0.0097
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0034 0.0216 0.0216
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0828 0.0828
Mycobacterium tuberculosis Cell division protein FtsZ 0.026 0.2332 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0177 0.0177
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0012 0.001 0.001
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0241 0.2156 0.2156
Echinococcus granulosus bloom syndrome protein 0.0023 0.012 0.012
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0062 0.048 0.7492
Onchocerca volvulus 0.0015 0.0036 0.0068
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0031 0.0031
Echinococcus multilocularis tyrosine protein kinase HCK 0.0034 0.022 0.022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0177 0.0177
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0177 0.0177
Echinococcus multilocularis neuroglian 0.0015 0.0038 0.0038
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0375 0.3406 0.3406
Echinococcus granulosus active breakpoint cluster region 0.0302 0.2724 0.2724
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Giardia lamblia NADPH oxidoreductase, putative 0.0241 0.2156 0.2091
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.048 0.048
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0027 0.0027
Brugia malayi Tyrosine-protein kinase abl-1 0.0183 0.1612 0.1612
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0039 0.0263 0.0767
Onchocerca volvulus 0.0015 0.0036 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0046 0.0046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0177 0.0177
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0046 0.0327 0.031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.001 0.001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0031 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Onchocerca volvulus 0.005 0.0364 0.0765
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0552 0.5066 0.5066
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0034 0.0034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Trichomonas vaginalis tubulin alpha chain, putative 0.0331 0.2992 0.2992
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0039 0.0263 0.0767
Echinococcus granulosus tyrosine protein kinase shark 0.0015 0.0042 0.0042
Echinococcus granulosus tubulin alpha chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0364 0.0364
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0046 0.0327 0.0327
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0223 0.0223
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Leishmania major protein kinase, putative 0.0062 0.048 0.048
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Onchocerca volvulus 0.0331 0.2992 0.6358
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0033 0.0033
Schistosoma mansoni alpha glucosidase 0.0036 0.024 0.024
Loa Loa (eye worm) norepinephrine transporter 0.0292 0.2632 0.2632
Onchocerca volvulus 0.0179 0.1572 0.3336
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0036
Mycobacterium tuberculosis Conserved protein 0.0035 0.0231 0.0762
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Entamoeba histolytica tubulin family protein 0.1079 1 1
Echinococcus multilocularis carbonic anhydrase 0.0328 0.2965 0.2965
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0142 0.1229 0.1214
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0041 0.0283 0.0283
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0004 0.0004
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.1434 0.1434
Schistosoma mansoni cell polarity protein 0.0034 0.0216 0.0216
Brugia malayi SRC-1 0.0054 0.0403 0.0403
Echinococcus granulosus epidermal growth factor receptor 0.0155 0.135 0.135
Schistosoma mansoni notch 0.0034 0.0216 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.026 0.2332 0.2332
Echinococcus multilocularis tubulin delta chain 0.026 0.2332 0.2332
Schistosoma mansoni adapter molecule crk 0.002 0.0082 0.0082
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0062 0.048 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0177 0.0177
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0203 0.0203
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0231 0.0642
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0048 0.0346 0.0329
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0024 0.0126 0.0126
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0371 0.1122
Mycobacterium tuberculosis Probable reductase 0.0213 0.1895 0.8078
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0093 0.0093
Loa Loa (eye worm) tubulin alpha-2 chain 0.0812 0.7498 0.7498
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.2014 0.8602
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0619 0.0619
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0066 0.0066
Echinococcus granulosus chromobox protein 1 0.0068 0.0538 0.0538
Echinococcus multilocularis multidrug resistance protein 1 0.0015 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.048 0.048
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0081 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0004 0.0004
Toxoplasma gondii ABC1 family protein 0.0035 0.0231 0.0231
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0177 0.0177
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0484 0.0484
Plasmodium vivax hypothetical protein, conserved 0.005 0.0364 0.0364
Echinococcus multilocularis Tubulin beta 2C chain 0.1079 1 1
Schistosoma mansoni lipoxygenase 0.0019 0.0081 0.0081
Leishmania major beta tubulin 0.1079 1 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0039 0.0263 0.0901
Echinococcus granulosus carbonic anhydrase 0.0328 0.2965 0.2965
Schistosoma mansoni notch 0.0034 0.0216 0.0216
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Plasmodium falciparum phosphodiesterase delta, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.026 0.2332 0.2332
Leishmania major beta tubulin 0.1079 1 1
Echinococcus granulosus cytochrome P450 2K1 0.0039 0.0263 0.0263
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0097 0.0097
Echinococcus granulosus cpg binding protein 0.0031 0.0186 0.0186
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0513 0.4695 0.4695
Echinococcus multilocularis intersectin 2 0.0014 0.0027 0.0027
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) animal heme peroxidase 0.0143 0.1241 0.1241
Trypanosoma cruzi zeta tubulin, putative 0.026 0.2332 0.2319
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0097 0.0097
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0451 0.4124 0.4124
Plasmodium falciparum tubulin gamma chain 0.0591 0.5425 0.5425
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Giardia lamblia High cysteine protein 0.0034 0.0216 0.0136
Mycobacterium leprae cell division protein FtsZ 0.026 0.2332 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0097 0.0097
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0062 0.0122
Leishmania major cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.0327
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0591 0.5425 0.5425
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0319 0.0319
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 0.0619
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0203 0.0542
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) notch protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0024 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0033
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0039 0.0263 0.0246
Loa Loa (eye worm) TK protein kinase 0.0108 0.0907 0.0907
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Mycobacterium ulcerans cell division protein FtsZ 0.026 0.2332 0.8866
Schistosoma mansoni multidrug resistance protein 0.0021 0.0097 0.0097
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0004 0.0004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0258 0.0539
Onchocerca volvulus 0.0021 0.0097 0.0198
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus insulin receptor 0.0052 0.0388 0.0388
Schistosoma mansoni ran 0.0021 0.0095 0.0095
Giardia lamblia Alpha-tubulin 0.0812 0.7498 0.7478
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0062 0.048 0.048
Leishmania major beta tubulin 0.1079 1 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Loa Loa (eye worm) tubulin beta chain 0.026 0.2332 0.2332
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.0216 0.0216
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0095 0.0078
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0105 0.0879 0.0879
Brugia malayi nuclear receptor RXR 0.0016 0.0046 0.0046
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Schistosoma mansoni tyrosine kinase 0.0015 0.0042 0.0042
Echinococcus multilocularis tubulin alpha 3 chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0538 0.0538
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0375 0.3406 0.3352
Echinococcus multilocularis insulin receptor 0.0052 0.0388 0.0388
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0031 0.0031
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0193 0.0193
Brugia malayi Furin-like cysteine rich region family protein 0.0155 0.135 0.135
Plasmodium falciparum tubulin epsilon chain, putative 0.0591 0.5425 0.5425
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0223 0.0206
Brugia malayi Thioredoxin reductase 0.0093 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0292 0.2632 0.2632
Trypanosoma brucei beta tubulin 0.1079 1 1
Plasmodium vivax glutathione reductase, putative 0.0093 0.0775 0.0775
Brugia malayi Animal haem peroxidase family protein 0.0143 0.1241 0.1241
Onchocerca volvulus 0.0035 0.0231 0.0482
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.006 0.0464 0.0464
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0031 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0039 0.0263 0.0901
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0216 0.0216
Plasmodium falciparum transporter, putative 0.005 0.0364 0.0364
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.024 0.0223
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0015 0.0036 0.0036
Onchocerca volvulus 0.0513 0.4704 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0387 0.0387
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.048 0.048
Schistosoma mansoni coup transcription factor 0.003 0.0177 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0153 0.0153
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0177 0.0177
Schistosoma mansoni carbonic anhydrase-related 0.0328 0.2965 0.2965
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0041 0.0283 0.0283
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0177 0.0177
Echinococcus granulosus protein jagged 2 0.0034 0.0216 0.0216
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0027 0.0027
Plasmodium vivax tubulin alpha chain, putative 0.0812 0.7498 0.7498
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0048 0.0346 0.0346
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0429 0.0429
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0027 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0123 0.0123
Echinococcus granulosus Tubulin beta 2C chain 0.1079 1 1
Echinococcus granulosus tubulin epsilon chain 0.0591 0.5425 0.5425
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0046 0.0327 0.0327
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0033 0.0033
Echinococcus granulosus carbonic anhydrase II 0.0513 0.4695 0.4695
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0538 0.0538
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0039 0.0263 0.0767
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Brugia malayi glutathione reductase 0.0093 0.0775 0.0775
Echinococcus multilocularis cpg binding protein 0.0031 0.0186 0.0186
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0097 0.0097
Leishmania major DNA topoisomerase IB, large subunit 0.0142 0.1229 0.1229
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0329 0.0329
Echinococcus granulosus peroxisome assembly protein 26 0.0812 0.7498 0.7498
Echinococcus multilocularis tubulin alpha chain 0.0812 0.7498 0.7498
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0177 0.0177
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0046 0.0327 0.0327
Treponema pallidum cell division protein FtsZ 0.026 0.2332 0.8826
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Leishmania major beta tubulin 0.1079 1 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0403 0.0403
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.026 0.2332 0.2332
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Brugia malayi Pre-SET motif family protein 0.0208 0.185 0.185
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0329 0.2979 0.2979
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0381 0.3467 0.3467
Brugia malayi PAS domain containing protein 0.0239 0.2133 0.2133
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0046 0.0327 0.0327
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0231 0.0231
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.024 0.024
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Loa Loa (eye worm) DNA topoisomerase I 0.019 0.1676 0.1676
Brugia malayi Tubulin beta chain 0.0331 0.2992 0.2992
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0364 0.0364
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0263 0.0263
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0203 0.0203
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0319 0.0319
Giardia lamblia Beta tubulin 0.1079 1 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0237 0.2118 0.9057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.006 0.0464 0.0464
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0039 0.0263 0.0901
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0046 0.0327 0.0327
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0619 0.0619
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0046 0.0327 0.031
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0039 0.0263 0.0901
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0033 0.0033
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0097 0.0097
Giardia lamblia Delta tubulin 0.026 0.2332 0.227
Mycobacterium ulcerans glutaminase 0.0291 0.2622 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0203 0.0203
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0364 0.0364
Trypanosoma cruzi epsilon tubulin, putative 0.0591 0.5425 0.5417
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0604 0.5548 0.5548
Echinococcus granulosus tubulin alpha 0.0591 0.5425 0.5425
Giardia lamblia Epsilon tubulin 0.026 0.2332 0.227
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.006 0.0464 0.0464
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0407 0.0407
Echinococcus granulosus tubulin alpha 1C chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) serotonin transporter b 0.0292 0.2632 0.2632
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus nuclear factor of activated T cells 5 0.0219 0.195 0.195
Loa Loa (eye worm) BEN-1 protein 0.1079 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0812 0.7498 0.7498
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0193 0.0193
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0203 0.0203
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0046 0.0327 0.0327
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0031 0.0031
Loa Loa (eye worm) TK/ABL protein kinase 0.043 0.3921 0.3921
Leishmania major beta tubulin 0.1079 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni notch 0.0034 0.0216 0.0216
Echinococcus granulosus carbonic anhydrase 0.0328 0.2965 0.2965
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0036
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.048 0.0464
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Brugia malayi Cytochrome P450 family protein 0.0039 0.0263 0.0263
Trichomonas vaginalis esterase, putative 0.0035 0.0231 0.0231
Brugia malayi Delta serrate ligand family protein 0.0034 0.0216 0.0216
Schistosoma mansoni hypothetical protein 0.0019 0.0081 0.0081
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0046 0.0327 0.0327
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0364 0.0364
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0017 0.0017
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0097 0.0097
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0031 0.0031
Onchocerca volvulus Neurogenic locus notch homolog 0.0034 0.0221 0.0461
Trypanosoma brucei alpha tubulin, putative 0.0331 0.2992 0.2992
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0203
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0105 0.0879 0.0879
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0081 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Brugia malayi Cytochrome P450 family protein 0.0039 0.0263 0.0263
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0216 0.0216
Schistosoma mansoni alpha tubulin 0.0812 0.7498 0.7498
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0004
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Schistosoma mansoni tubulin subunit alpha 0.0812 0.7498 0.7498
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0039 0.0263 0.0767
Echinococcus multilocularis transient receptor potential cation channel 0.0324 0.2932 0.2932
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0513 0.4695 0.4686
Echinococcus multilocularis peroxidasin 0.0146 0.1269 0.1269
Leishmania major gamma-tubulin 0.0591 0.5425 0.5425
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0046 0.0327 0.031
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0203 0.0203
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0329 0.0329
Leishmania major beta tubulin 0.1079 1 1
Echinococcus multilocularis active breakpoint cluster region 0.0302 0.2724 0.2724
Schistosoma mansoni vesicular amine transporter 0.0018 0.0071 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0039 0.0263 0.0901
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0429 0.0429
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.002 0.002
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0039 0.0263 0.0901
Plasmodium vivax phosphodiesterase gamma, putative 0.0046 0.0327 0.0327
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0289 0.0289
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Echinococcus granulosus peroxidasin 0.0146 0.1269 0.1269
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0216 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0177 0.0177
Schistosoma mansoni hypothetical protein 0.0604 0.5548 0.5548
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus RUN 0.0019 0.0081 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Leishmania major zeta tubulin, putative 0.026 0.2332 0.2332
Loa Loa (eye worm) tubulin beta-1 chain 0.1079 1 1
Plasmodium vivax tubulin epsilon chain, putative 0.0591 0.5425 0.5425
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0364 0.0364
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Onchocerca volvulus 0.0024 0.0123 0.0253
Brugia malayi Cell division protein ftsZ 0.026 0.2332 0.2332
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.0327
Trypanosoma cruzi zeta tubulin, putative 0.026 0.2332 0.2319
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0403 0.0403
Echinococcus granulosus death domain containing protein 0.0014 0.0033 0.0033
Onchocerca volvulus 0.003 0.0177 0.0368
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0177 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0027
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.1434 0.1434
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Trypanosoma brucei beta tubulin 0.1079 1 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0619 0.0619
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0062 0.048 0.0464
Echinococcus granulosus neurogenic locus protein delta 0.0034 0.0216 0.0216
Echinococcus granulosus defective proboscis extension response 0.0012 0.001 0.001
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0328 0.2965 0.2965
Schistosoma mansoni growth factor receptor-bound protein 0.002 0.0082 0.0082
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Echinococcus granulosus tubulin subunit beta 0.1079 1 1
Echinococcus granulosus tubulin alpha 3 chain 0.0812 0.7498 0.7498
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0081 0.0056
Plasmodium vivax tubulin gamma chain, putative 0.0591 0.5425 0.5425
Leishmania major beta tubulin 0.1079 1 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Echinococcus granulosus fibropellin Ia 0.0034 0.0216 0.0216
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0046 0.0327 0.0327
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0015 0.0036 0.0036
Echinococcus multilocularis fibropellin Ia 0.0034 0.0216 0.0216
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0203 0.0186
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0095 0.0095
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0203 0.0533
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Echinococcus granulosus aryl hydrocarbon receptor 0.0516 0.4723 0.4723
Trypanosoma brucei glucosidase, putative 0.0036 0.024 0.024
Brugia malayi hypothetical protein 0.0012 0.001 0.001
Onchocerca volvulus 0.0034 0.0216 0.0449
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0177 0.0177
Brugia malayi Animal haem peroxidase family protein 0.0146 0.1269 0.1269
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0039 0.0263 0.0901
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Loa Loa (eye worm) solute carrier family 6 member 4 0.0292 0.2632 0.2632
Loa Loa (eye worm) tubulin beta-2A chain 0.1079 1 1
Loa Loa (eye worm) PDE1B protein 0.0046 0.0327 0.0327
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0097 0.0097
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0364 0.0364
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.024 0.024
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0513 0.4695 0.4695
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus tubulin alpha 1C chain 0.0812 0.7498 0.7498
Schistosoma mansoni cpg binding protein 0.0029 0.017 0.017
Giardia lamblia Gamma tubulin 0.0591 0.5425 0.5388
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0237 0.2118 0.9057
Brugia malayi beta-lactamase family protein 0.0035 0.0231 0.0231
Schistosoma mansoni ap endonuclease 0.0019 0.0081 0.0081
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0827 0.0827
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0203 0.0533
Brugia malayi Augmenter of liver regeneration 0.0035 0.0223 0.0223
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0046 0.0327 0.0327
Loa Loa (eye worm) tubulin alpha 2 0.0552 0.5066 0.5066
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0203 0.0203
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0031 0.0031
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0031 0.0031
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.024 0.024
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0031 0.0031
Echinococcus granulosus protein jagged 1 0.0034 0.0216 0.0216
Brugia malayi Uncoordinated protein 44 0.0014 0.0033 0.0033
Plasmodium vivax topoisomerase I, putative 0.019 0.1676 0.1676
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0371 0.0371
Echinococcus granulosus tyrosine protein kinase Blk 0.0044 0.0313 0.0313
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0552 0.5066 0.5066
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0285 0.0285
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0015 0.0036 0.0036
Echinococcus granulosus tubulin alpha chain 0.0812 0.7498 0.7498
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0036
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0213 0.1895 0.8078
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0231 0.0231
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0033 0.0033
Brugia malayi Cytochrome P450 family protein 0.0039 0.0263 0.0263
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0298 0.0298
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0403 0.0403
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0319 0.0319
Echinococcus multilocularis protein patched 0.0043 0.0298 0.0298
Brugia malayi Importin beta-1 subunit 0.0057 0.0429 0.0429
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0298 0.0298
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0177 0.0177
Loa Loa (eye worm) beta-lactamase 0.0035 0.0231 0.0231
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0203 0.0203
Echinococcus granulosus growth factor receptor bound protein 2 0.002 0.0082 0.0082
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0097 0.0175
Brugia malayi hypothetical protein 0.0019 0.0081 0.0081
Plasmodium falciparum amino acid transporter, putative 0.005 0.0364 0.0364
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0223 0.0223
Loa Loa (eye worm) glutaminase 2 0.0291 0.2622 0.2622
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0403 0.0403
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0095 0.0095
Schistosoma mansoni chromobox protein 0.0068 0.0538 0.0538
Trichomonas vaginalis glutaminase, putative 0.0291 0.2622 0.2622
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Onchocerca volvulus Peroxidase homolog 0.0143 0.1241 0.2632
Echinococcus multilocularis carbonic anhydrase 0.0328 0.2965 0.2965
Brugia malayi nuclear receptor NHR-88 0.0014 0.0031 0.0031
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0031 0.0031
Trypanosoma brucei beta tubulin 0.1079 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0095 0.0095
Echinococcus granulosus tyrosine protein kinase Lyn 0.0054 0.0403 0.0403
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.031
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0203 0.0123
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0057 0.0429 0.0429
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0193 0.0193
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0097 0.0097
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0203
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Brugia malayi Tubulin beta chain 0.026 0.2332 0.2332
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0696 0.0696
Brugia malayi hypothetical protein 0.0012 0.001 0.001
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0193
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0046 0.0327 0.0327
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0213 0.1895 0.8078
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Onchocerca volvulus 0.0034 0.0216 0.0449
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0081 0.0081
Schistosoma mansoni notch 0.0034 0.0216 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0231 0.0231
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0263 0.0246
Echinococcus multilocularis tubulin alpha 3 chain 0.0812 0.7498 0.7498
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0027 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0203
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0177 0.0368
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0231 0.0762
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0081 0.0081
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.0004
Entamoeba histolytica protein kinase, putative 0.0034 0.022 0.022
Onchocerca volvulus 0.0034 0.0216 0.0449
Brugia malayi beta-tubulin, identical 0.1079 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.048 0.048
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0231 0.0231
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0231 0.0762
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0177 0.0177
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0067 0.0067
Trichomonas vaginalis tubulin alpha chain, putative 0.1079 1 1
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0241 0.2156 0.2156
Echinococcus granulosus Chromo domain 0.0011 0.0004 0.0004
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0241 0.2156 0.2156
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0328 0.2965 0.2965
Echinococcus multilocularis tubulin alpha chain 0.0812 0.7498 0.7498
Brugia malayi hypothetical protein 0.0143 0.1241 0.1241
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0177 0.0177
Brugia malayi Peroxidasin 0.0146 0.1269 0.1269
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0105 0.0879 0.0879
Brugia malayi RNA, U transporter 1 0.0161 0.1404 0.1404
Echinococcus multilocularis chromobox protein 1 0.0068 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0012 0.001 0.001
Schistosoma mansoni nuclear receptor 0.0014 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0046 0.0327 0.0327
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0193 0.0193
Echinococcus granulosus tubulin alpha 3 chain 0.0812 0.7498 0.7498
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0046 0.0327 0.031
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0203
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0269 0.0269
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0039 0.0263 0.0901
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0004 0.0004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.024 0.024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0054 0.0054
Echinococcus multilocularis ankyrin repeat protein 0.0317 0.2866 0.2866
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0403 0.0403
Trypanosoma brucei epsilon tubulin 0.0591 0.5425 0.5425
Brugia malayi MH2 domain containing protein 0.0117 0.0993 0.0993
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 0.2388
Loa Loa (eye worm) TK/EGFR protein kinase 0.0155 0.135 0.135
Brugia malayi Variant SH3 domain containing protein 0.002 0.0082 0.0082
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0038 0.0038
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0213 0.1895 0.8021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0298 0.0298
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0081 0.0081
Loa Loa (eye worm) DR-78 0.0014 0.0031 0.0031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0039 0.0263 0.0901
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0097 0.0097
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0097 0.0097
Onchocerca volvulus 0.0143 0.1241 0.2632
Schistosoma mansoni thyroid hormone receptor 0.003 0.0177 0.0177
Echinococcus multilocularis tubulin subunit TubB 0.0812 0.7498 0.7498
Echinococcus granulosus protein jagged 1 0.0034 0.0216 0.0216
Trichomonas vaginalis tubulin gamma chain, putative 0.0591 0.5425 0.5425
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Echinococcus granulosus delta-like protein 1 0.0034 0.0216 0.0216
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.012 0.012
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0285 0.0285
Leishmania major importin beta-1 subunit, putative 0.0046 0.0329 0.0329
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0004 0.0004
Brugia malayi hypothetical protein 0.0062 0.048 0.048
Echinococcus granulosus ankyrin repeat protein 0.0317 0.2866 0.2866
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0223 0.0206
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Echinococcus multilocularis fat cadherin tumor suppressor 0.0034 0.0216 0.0216
Echinococcus multilocularis carbonic anhydrase 0.0328 0.2965 0.2965
Schistosoma mansoni hypothetical protein 0.0669 0.6162 0.6162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0082 0.0082
Onchocerca volvulus 0.0143 0.1241 0.2632
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0177 0.0177
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0203 0.0203
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0216 0.0216
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0081 0.0081
Plasmodium vivax importin-beta 2, putative 0.0057 0.0429 0.0429
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0203
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0364 0.0364
Trichomonas vaginalis adenylate cyclase, putative 0.0062 0.048 0.048
Trichomonas vaginalis tubulin epsilon chain, putative 0.1079 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0093 0.0775 0.3152
Giardia lamblia hypothetical protein 0.0046 0.0327 0.0248
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Brugia malayi CHE-14 protein 0.0043 0.0298 0.0298
Echinococcus multilocularis Tubulin beta 2C chain 0.1079 1 1
Onchocerca volvulus 0.0143 0.1241 0.2632
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus Tubulin beta 2C chain 0.1079 1 1
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0223 0.0223
Echinococcus granulosus alpha tubulin 0.0812 0.7498 0.7498
Plasmodium falciparum thioredoxin reductase 0.0093 0.0775 0.0775
Loa Loa (eye worm) TK protein kinase 0.0044 0.0313 0.0313
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0696 0.0696
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0177 0.0177
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0097 0.0097
Leishmania major hypothetical protein, conserved 0.0035 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0123 0.0288
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0046 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Echinococcus granulosus FTZ F1 alpha 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Echinococcus granulosus snurportin 1 0.0604 0.5548 0.5548
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0039 0.0263 0.0767
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0193
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0364 0.0364
Schistosoma mansoni hypothetical protein 0.0039 0.0263 0.0263
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.024 0.024
Onchocerca volvulus 0.0029 0.017 0.0353
Plasmodium falciparum alpha tubulin 2 0.0812 0.7498 0.7498
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0364 0.0364
Brugia malayi nuclear hormone receptor 0.003 0.0177 0.0177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0033 0.0033
Brugia malayi Doublecortin family protein 0.0019 0.0081 0.0081
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 0.216
Echinococcus granulosus Tubulin beta 2C chain 0.1079 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0258 0.0258
Leishmania major hypothetical protein, conserved 0.0046 0.0327 0.0327
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0203 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0081 0.0064
Brugia malayi hypothetical protein 0.0016 0.0046 0.0046
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Loa Loa (eye worm) hypothetical protein 0.0375 0.3406 0.3406
Trypanosoma brucei alpha tubulin 0.0812 0.7498 0.7498
Onchocerca volvulus 0.003 0.018 0.0374
Brugia malayi SH2 domain containing protein 0.0015 0.0036 0.0036
Treponema pallidum sodium- and chloride- dependent transporter 0.0292 0.2632 1
Echinococcus granulosus tubulin alpha chain 0.0812 0.7498 0.7498
Mycobacterium leprae Possible regulatory protein 0.0062 0.048 0.1617
Echinococcus multilocularis Ankyrin 0.0015 0.0039 0.0039
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1434 0.1434
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Trichomonas vaginalis abcb9, putative 0.0021 0.0097 0.0097
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0513 0.4695 0.4695
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0039 0.0263 0.0767
Brugia malayi alpha-tubulin 0.0812 0.7498 0.7498
Trichomonas vaginalis tubulin beta chain, putative 0.1079 1 1
Schistosoma mansoni tubulin subunit alpha 0.026 0.2332 0.2332
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.048 0.048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Onchocerca volvulus Dual oxidase homolog 0.0143 0.1241 0.2632
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0033 0.0033
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0039 0.0263 0.0901
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0203 0.0203
Loa Loa (eye worm) alpha-tubulin 0.0812 0.7498 0.7498
Plasmodium falciparum phosphodiesterase gamma, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0024 0.0123 0.0123
Trichomonas vaginalis abcb9, putative 0.0021 0.0097 0.0097
Onchocerca volvulus 0.0011 0.0004 0.0000001737
Leishmania major beta tubulin 0.1079 1 1
Brugia malayi Cytochrome P450 family protein 0.0039 0.0263 0.0263
Schistosoma mansoni rab6-interacting 0.0019 0.0081 0.0081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Schistosoma mansoni nuclear hormone receptor 0.003 0.0177 0.0177
Echinococcus granulosus tyrosine protein kinase ABL1 0.043 0.3921 0.3921
Echinococcus multilocularis tubulin beta 1 chain 0.1079 1 1
Brugia malayi conserved hypotetical protein 0.0014 0.0031 0.0031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0177 0.0177
Onchocerca volvulus 0.005 0.0364 0.0765
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 0.216
Trypanosoma brucei zeta tubulin 0.026 0.2332 0.2332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0123 0.0221
Echinococcus granulosus protein jagged 2 0.0034 0.0216 0.0216
Brugia malayi Tubulin alpha chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0828 0.0828
Leishmania major beta tubulin 0.1079 1 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0375 0.3406 0.3406
Mycobacterium tuberculosis Probable oxidoreductase 0.0237 0.2118 0.9057
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0619 0.2243
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.0327
Toxoplasma gondii EGF family domain-containing protein 0.0034 0.0216 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0123 0.0123
Loa Loa (eye worm) BEN-1 protein 0.1079 1 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis hypothetical protein 0.0812 0.7498 0.7498
Loa Loa (eye worm) thioredoxin reductase 0.0093 0.0775 0.0775
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0046 0.0327 0.0327
Schistosoma mansoni tyrosine kinase 0.008 0.0652 0.0652
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0027
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) animal heme peroxidase 0.0146 0.1269 0.1269
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0328 0.2965 0.2965
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0031 0.0031
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0827 0.0827
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0216 0.0216
Plasmodium vivax tubulin alpha chain, putative 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0039
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0012 0.001 0.001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0231 0.0231
Echinococcus granulosus expressed conserved protein 0.0093 0.0771 0.0771
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0327 0.0327
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0046 0.0327 0.031
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0177 0.0368
Leishmania major beta tubulin 0.1079 1 1
Giardia lamblia Alpha-tubulin 0.0812 0.7498 0.7478
Loa Loa (eye worm) tubulin alpha 2 0.0222 0.1973 0.1973
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0482 0.4406 0.4406
Brugia malayi beta-lactamase family protein 0.0035 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.002 0.0082 0.0082
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0046 0.0327 0.0327
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0081 0.0081
Brugia malayi hypothetical protein 0.005 0.0364 0.0364
Brugia malayi DNA topoisomerase I 0.019 0.1676 0.1676
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0364 0.5379
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Brugia malayi Muscle positioning protein 4 0.0034 0.0216 0.0216
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0364 0.0364
Schistosoma mansoni cell adhesion molecule 0.0012 0.001 0.001
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0909 0.8402 0.8402
Schistosoma mansoni septate junction protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Giardia lamblia Beta tubulin 0.1079 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0177 0.0177
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0185 0.0185
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0123 0.0221
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Leishmania major beta tubulin 0.1079 1 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0513 0.4695 0.4695
Brugia malayi Immunoglobulin I-set domain containing protein 0.0108 0.0907 0.0907
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0827 0.0827
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0177 0.0177
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.006 0.0464 0.0464
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0371 0.1378
Onchocerca volvulus 0.0014 0.0031 0.0056
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0004 0.0004
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0038 0.0038
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0039 0.0263 0.0901
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0669 0.6162 0.6162
Echinococcus granulosus tubulin delta chain 0.026 0.2332 0.2332
Leishmania major p-glycoprotein 0.0021 0.0097 0.0097
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Entamoeba histolytica tubulin family protein 0.1079 1 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0619 0.0619
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0841 0.0841
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Schistosoma mansoni tubulin subunit epsilon 0.0591 0.5425 0.5425
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Schistosoma mansoni alpha-glucosidase 0.0141 0.122 0.122
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0027
Echinococcus multilocularis tubulin alpha chain 0.0812 0.7498 0.7498
Echinococcus granulosus Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0052 0.0387 0.0387
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0081 0.0081
Trypanosoma brucei beta tubulin 0.1079 1 1
Brugia malayi Variant SH3 domain containing protein 0.0014 0.0028 0.0028
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1434 0.1434
Echinococcus multilocularis 0.0047 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0027 0.0048
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0046 0.0327 0.0327
Leishmania major hypothetical protein, conserved 0.0035 0.0231 0.0231
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.012 0.012
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0203 0.2469
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0203 0.0639
Echinococcus multilocularis tyrosine protein kinase shark 0.0015 0.0042 0.0042
Schistosoma mansoni glutaminase 0.0291 0.2622 0.2622
Echinococcus multilocularis tyrosine kinase 0.0015 0.0036 0.0036
Schistosoma mansoni alpha tubulin 0.0812 0.7498 0.7498
Plasmodium falciparum topoisomerase I 0.019 0.1676 0.1676
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0223 0.0223
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus NCK adaptor protein 0.002 0.0082 0.0082
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus tyrosine kinase 0.0044 0.0313 0.0313
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0231 0.0762
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Echinococcus granulosus importin subunit beta 1 0.0057 0.0429 0.0429
Schistosoma mansoni tyrosine kinase 0.0052 0.0388 0.0388
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0451 0.4124 0.4124
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0231 0.0762
Loa Loa (eye worm) tubulin alpha chain 0.0812 0.7498 0.7498
Echinococcus multilocularis RUN 0.0019 0.0081 0.0081
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0223 0.0223
Entamoeba histolytica tubulin gamma chain 0.0591 0.5425 0.5425
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0097 0.0097
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0046 0.0327 0.0327
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0123 0.0123
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.002 0.002
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0039 0.0263 0.0263
Echinococcus granulosus Immunoglobulin 0.0012 0.001 0.001
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0619 0.0619
Schistosoma mansoni DNA topoisomerase type I 0.0142 0.1229 0.1229
Schistosoma mansoni tyrosine kinase 0.042 0.3829 0.3829
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0031 0.0031
Trypanosoma brucei epsilon tubulin 0.0591 0.5425 0.5425
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0081 0.0081
Brugia malayi SH2 domain containing protein 0.0015 0.0036 0.0036
Brugia malayi nuclear receptor NHR-67 0.0014 0.0031 0.0031
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Toxoplasma gondii hypothetical protein 0.005 0.0364 0.0364
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0319 0.0319
Giardia lamblia NADPH oxidoreductase, putative 0.0241 0.2156 0.2091
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0185 0.0185
Brugia malayi Heterochromatin protein 1 0.0068 0.0538 0.0538
Leishmania major beta tubulin 0.1079 1 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0095 0.0078
Echinococcus multilocularis chromobox protein 1 0.0068 0.0538 0.0538
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.024 0.024
Entamoeba histolytica hypothetical protein 0.006 0.0464 0.0464
Schistosoma mansoni tyrosine kinase 0.0054 0.0403 0.0403
Trichomonas vaginalis tubulin alpha chain, putative 0.0591 0.5425 0.5425
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0148 0.0111
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0329 0.0312
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus twitchin 0.0015 0.0038 0.0038
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0062 0.048 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Brugia malayi Tubulin alpha-2 chain 0.0812 0.7498 0.7498
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0319 0.0319
Schistosoma mansoni tyrosine kinase 0.0155 0.135 0.135
Schistosoma mansoni DNA topoisomerase type I 0.0142 0.1229 0.1229
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Brugia malayi multidrug resistance protein 3 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0046 0.0046
Brugia malayi Animal haem peroxidase family protein 0.0143 0.1241 0.1241
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Echinococcus multilocularis Chromo domain 0.0011 0.0004 0.0004
Leishmania major delta tubulin, putative 0.026 0.2332 0.2332
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni alpha-glucosidase 0.0141 0.122 0.122
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0828 0.0828
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0364 0.0364
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0062 0.048 0.048
Trichomonas vaginalis conserved hypothetical protein 0.026 0.2332 0.2332
Trichomonas vaginalis guanylate cyclase, putative 0.0062 0.048 0.048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0081 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0328 0.2965 0.2965
Schistosoma mansoni carbonic anhydrase-related 0.0328 0.2965 0.2965
Trypanosoma brucei tubulin delta chain 0.026 0.2332 0.2332
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0081 0.0081
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0388 0.0388
Schistosoma mansoni slit 0.0034 0.0216 0.0216
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0031 0.0031
Loa Loa (eye worm) blistered cuticle protein 3 0.0143 0.1241 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0039 0.0263 0.0767
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0046 0.0327 0.0327
Brugia malayi hypothetical protein 0.0014 0.0031 0.0031
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0123 0.0123
Brugia malayi protein-tyrosine kinase 0.0044 0.0313 0.0313
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0039 0.0263 0.0767
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0364 0.0364
Plasmodium falciparum thioredoxin reductase 0.0032 0.0203 0.0203
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0004 0.0004
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0046 0.0327 0.0327
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0081 0.0081
Leishmania major cytochrome p450-like protein 0.0039 0.0263 0.0263
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0081 0.0103
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0619 0.0619
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0193
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0004
Echinococcus multilocularis Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Echinococcus multilocularis slit 2 protein 0.0034 0.0216 0.0216
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0046 0.0327 0.0327
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0298 0.0298
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0319 0.0319
Trichomonas vaginalis taga, putative 0.0021 0.0097 0.0097
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0177 0.0177
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0081 0.0081
Brugia malayi SET domain containing protein 0.0013 0.0021 0.0021
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0093 0.0775 0.0775
Trypanosoma brucei trypanothione reductase 0.0093 0.0775 0.0775
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0231 0.0488
Brugia malayi Blistered cuticle protein 3 0.0143 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0039 0.0263 0.0901
Brugia malayi hypothetical protein 0.0016 0.0046 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0203 0.0542
Toxoplasma gondii cytochrome p450 superfamily protein 0.0039 0.0263 0.0263
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Loa Loa (eye worm) hypothetical protein 0.003 0.0185 0.0185
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0177 0.0177
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Trypanosoma brucei zeta tubulin, putative 0.026 0.2332 0.2332
Plasmodium vivax SET domain protein, putative 0.003 0.0185 0.0185
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0031 0.0031
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0067 0.004
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Brugia malayi Animal haem peroxidase family protein 0.0143 0.1241 0.1241
Onchocerca volvulus 0.0015 0.0036 0.0068
Entamoeba histolytica tubulin alpha chain, putative 0.0812 0.7498 0.7498
Trichomonas vaginalis tubulin, putative 0.0331 0.2992 0.2992
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.048 0.048
Echinococcus granulosus tubulin beta 1 chain 0.1079 1 1
Echinococcus granulosus tubulin alpha chain 0.0812 0.7498 0.7498
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0031 0.0031
Onchocerca volvulus 0.0019 0.0081 0.0163
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.2274 0.2274
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Brugia malayi Protein cec-1. 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0177 0.0177
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0364 0.0364
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0203 0.0203
Onchocerca volvulus Peroxidase homolog 0.0143 0.1241 0.2632
Echinococcus granulosus GPCR family 2 0.0031 0.0193 0.0193
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0123 0.0288
Loa Loa (eye worm) tubulin alpha chain 0.0812 0.7498 0.7498
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0097 0.0097
Onchocerca volvulus 0.0035 0.0231 0.0482
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Trichomonas vaginalis tubulin epsilon chain, putative 0.0812 0.7498 0.7498
Echinococcus multilocularis peroxisome assembly protein 26 0.0812 0.7498 0.7498
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0036
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0177 0.0177
Schistosoma mansoni aryl hydrocarbon receptor 0.0692 0.6376 0.6376
Schistosoma mansoni smdr2 0.0021 0.0097 0.0097
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 0.2108
Brugia malayi chromobox protein homolog 3 0.0038 0.0258 0.0258
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2119 0.2119
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1541 0.1541
Echinococcus granulosus fibroblast growth factor receptor 4 0.0105 0.0879 0.0879
Echinococcus multilocularis epidermal growth factor receptor 0.0155 0.135 0.135
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0039 0.0263 0.0767
Schistosoma mansoni hypothetical protein 0.0328 0.2965 0.2965
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0027 0.0027
Trypanosoma brucei beta tubulin 0.0591 0.5425 0.5425
Brugia malayi cytochrome P450 0.0039 0.0263 0.0263
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0046 0.0327 0.0327
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0039 0.0263 0.0246
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0482 0.4406 0.4406
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Toxoplasma gondii beta-tubulin, putative 0.1079 1 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0024 0.0126 0.0126
Echinococcus granulosus slit 2 protein 0.0034 0.0216 0.0216
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0193
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0027 0.0027
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0364 0.0364
Leishmania major trypanothione reductase 0.0093 0.0775 0.0775
Echinococcus multilocularis tubulin alpha 1C chain 0.0812 0.7498 0.7498
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0027
Brugia malayi CXXC zinc finger family protein 0.0029 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Echinococcus multilocularis neurogenic locus notch protein 4 0.0034 0.0216 0.0216
Loa Loa (eye worm) SRC-1 0.0054 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0038
Echinococcus multilocularis protein dispatched 1 0.0049 0.0354 0.0354
Loa Loa (eye worm) alpha-tubulin 0.0812 0.7498 0.7498
Plasmodium falciparum carbonic anhydrase 0.0328 0.2965 0.2965
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis DNA topoisomerase 1 0.019 0.1676 0.1676
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0185 0.0185
Trichomonas vaginalis tubulin, putative 0.0331 0.2992 0.2992
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Brugia malayi Sex muscle abnormal protein 5 0.002 0.0082 0.0082
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Echinococcus granulosus chromobox protein 2 0.0011 0.0004 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0177 0.0177
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0313 0.0313
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0033 0.0033
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0046 0.0327 0.0327
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Onchocerca volvulus 0.0042 0.0289 0.0606
Echinococcus multilocularis carbonic anhydrase II 0.0513 0.4695 0.4695
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0017 0.0017
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0097 0.0097
Trypanosoma brucei cytochrome P450, putative 0.0039 0.0263 0.0263
Plasmodium falciparum tubulin beta chain 0.1079 1 1
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Trichomonas vaginalis tubulin epsilon chain, putative 0.026 0.2332 0.2332
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.1225 0.1225
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Onchocerca volvulus 0.0015 0.0036 0.0068
Leishmania major beta tubulin 0.1079 1 1
Schistosoma mansoni tubulin subunit alpha 0.0812 0.7498 0.7498
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0038 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0039 0.0263 0.0901
Toxoplasma gondii hypothetical protein 0.0328 0.2965 0.2965
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0364 0.0364
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0031 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Loa Loa (eye worm) hypothetical protein 0.0513 0.4704 0.4704
Entamoeba histolytica tubulin alpha-1 chain 0.0812 0.7498 0.7498
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0364 0.0364
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0039 0.0263 0.0767
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0095 0.0095
Loa Loa (eye worm) tubulin alpha-3 chain 0.0482 0.4406 0.4406
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0031 0.0031
Trypanosoma cruzi alpha tubulin, putative 0.0812 0.7498 0.7494
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.6397 0.6397
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0216 0.0216
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0004 0.0004
Echinococcus multilocularis tubulin subunit beta 0.1079 1 1
Toxoplasma gondii hypothetical protein 0.005 0.0364 0.0364
Echinococcus granulosus Tubulin beta 2C chain 0.1079 1 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1079 1 1
Brugia malayi Tubulin alpha-2 chain 0.0812 0.7498 0.7498
Schistosoma mansoni netrin receptor unc5 0.0014 0.0033 0.0033
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0328 0.2965 0.2965
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0231 0.0231
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Schistosoma mansoni carbonic anhydrase-related 0.0328 0.2965 0.2965
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Schistosoma mansoni chromobox protein 0.0068 0.0538 0.0538
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0046 0.0327 0.0327
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0039 0.0263 0.0767
Loa Loa (eye worm) hypothetical protein 0.0328 0.2965 0.2965
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0177 0.0177
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.2274 0.2274
Brugia malayi CHD4 protein 0.0013 0.002 0.002
Echinococcus multilocularis Tubulin beta 2C chain 0.1079 1 1
Echinococcus multilocularis serotonin transporter 0.0292 0.2632 0.2632
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0014 0.0028 0.0028
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0285 0.0596
Schistosoma mansoni DNA topoisomerase type I 0.019 0.1676 0.1676
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Treponema pallidum NADH oxidase 0.0032 0.0203 0.0478
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.048 0.0464
Plasmodium vivax tubulin beta chain, putative 0.1079 1 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0068 0.0534 0.0534
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Plasmodium falciparum importin beta, putative 0.0057 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0046 0.0046
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0081 0.0081
Brugia malayi Animal haem peroxidase family protein 0.0143 0.1241 0.1241
Leishmania major protein kinase, putative 0.0062 0.048 0.048
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0123 0.0123
Echinococcus granulosus serotonin transporter 0.0292 0.2632 0.2632
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Trypanosoma brucei alpha tubulin 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0099 0.0828 0.0828
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0067 0.0067
Schistosoma mansoni ap endonuclease 0.0019 0.0081 0.0081
Echinococcus multilocularis protein jagged 1 0.0034 0.0216 0.0216
Echinococcus multilocularis beta tubulin 0.1079 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Brugia malayi EGF-like domain containing protein 0.0034 0.0216 0.0216
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0097 0.0555
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0364 0.0364
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0403 0.0403
Echinococcus multilocularis transfer RNA-Lys 0.0177 0.1553 0.1553
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Leishmania major beta tubulin 0.1079 1 1
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.6397 0.6397
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0039 0.0263 0.0767
Echinococcus multilocularis chromobox protein 2 0.0011 0.0004 0.0004
Brugia malayi Tyrosine-protein kinase abl-1 0.0256 0.2299 0.2299
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0375 0.3406 0.3406
Loa Loa (eye worm) hypothetical protein 0.0454 0.4143 0.4143
Onchocerca volvulus 0.0034 0.0216 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0044 0.0313 0.0313
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0177 0.0177
Trichomonas vaginalis tubulin gamma chain, putative 0.026 0.2332 0.2332
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0403 0.0403
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0036
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0046 0.0046
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus beta tubulin 0.1079 1 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0031 0.0031
Echinococcus multilocularis expressed conserved protein 0.0093 0.0771 0.0771
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0177 0.0177
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0004 0.0004
Echinococcus multilocularis roundabout 2 0.0015 0.0038 0.0038
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.3751 0.3751
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0327 0.0327
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0193 0.0193
Echinococcus multilocularis tyrosine protein kinase Srms 0.0044 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Onchocerca volvulus 0.0019 0.0081 0.0163
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.1225 0.1225
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0993 0.0993
Loa Loa (eye worm) cytochrome P450 0.0039 0.0263 0.0263
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0095 0.0095
Echinococcus granulosus Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0292 0.2632 0.2632
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0185 0.0185
Echinococcus multilocularis tubulin alpha chain 0.0812 0.7498 0.7498
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Schistosoma mansoni hypothetical protein 0.0068 0.0534 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0177 0.0177
Onchocerca volvulus 0.0014 0.0031 0.0056
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0046
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.024 0.024
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus dnaJ subfamily B 0.0412 0.3751 0.3751
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0237 0.2118 0.9029
Trypanosoma brucei tubulin gamma chain 0.0591 0.5425 0.5425
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Echinococcus multilocularis tyrosine protein kinase Blk 0.0044 0.0313 0.0313
Schistosoma mansoni single-minded 0.0239 0.2133 0.2133
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0231 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0185 0.0185
Echinococcus granulosus thioredoxin glutathione reductase 0.0093 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0292 0.2632 0.2632
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0329 0.2979 0.2979
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni rab6-interacting 0.0019 0.0081 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0039 0.0263 0.0901
Echinococcus multilocularis geminin 0.0669 0.6162 0.6162
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0016 0.0054 0.0054
Loa Loa (eye worm) RecQ helicase 0.0023 0.012 0.012
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0039 0.0263 0.0901
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.0004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Onchocerca volvulus Peroxidasin homolog 0.0146 0.1269 0.2692
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0329 0.2979 0.2979
Echinococcus multilocularis tubulin alpha chain 0.0812 0.7498 0.7498
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Echinococcus multilocularis growth factor receptor bound protein 2 0.002 0.0082 0.0082
Brugia malayi Probable ClpP-like protease 0.0077 0.0619 0.0619
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0064 0.05 0.05
Echinococcus granulosus tubulin beta 4A class IVa 0.1079 1 1
Schistosoma mansoni carbonic anhydrase 0.0328 0.2965 0.2965
Leishmania major GTP-binding protein, putative 0.0021 0.0095 0.0095
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0142 0.1229 0.1229
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0148 0.0148
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0177 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0095 0.0095
Trichomonas vaginalis ran, putative 0.0021 0.0095 0.0095
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0827 0.0827
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0177 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.024 0.024
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0329 0.2979 0.2979
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.026 0.2332 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0095 0.0095
Echinococcus granulosus neurogenic locus notch protein 4 0.0034 0.0216 0.0216
Brugia malayi Tubulin alpha chain 0.026 0.2332 0.2332
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Leishmania major beta tubulin 0.1079 1 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0513 0.4695 0.4695
Echinococcus granulosus tubulin alpha chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0177 0.0177
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0004 0.0004
Loa Loa (eye worm) CYP4Cod1 0.0039 0.0263 0.0263
Brugia malayi nuclear hormone receptor 0.0014 0.0031 0.0031
Trypanosoma cruzi beta tubulin, putative 0.1079 1 1
Schistosoma mansoni peroxidasin 0.0143 0.1241 0.1241
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0231 0.0231
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0095 0.0095
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0046 0.0327 0.0327
Leishmania major DNA topoisomerase type IB small subunit 0.0048 0.0346 0.0346
Echinococcus multilocularis Tubulin beta 2C chain 0.1079 1 1
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0046 0.0327 0.0327
Echinococcus granulosus c src tyrosine kinase 0.0024 0.0126 0.0126
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0193 0.0193
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus single minded 2 0.0177 0.1553 0.1553
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0095 0.0014
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0429 0.0429
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0095 0.0095
Trichomonas vaginalis tubulin gamma chain, putative 0.1079 1 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0331 0.2992 0.2992
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0004 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0123 0.0123
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0216 0.0216
Mycobacterium leprae putative cytochrome p450 0.0039 0.0263 0.0632
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0118 0.1006 0.1006
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0081 0.0081
Echinococcus multilocularis notch 0.0034 0.0216 0.0216
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0039 0.0263 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0097
Echinococcus multilocularis tubulin alpha 1C chain 0.0812 0.7498 0.7498
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0039 0.0263 0.0901
Toxoplasma gondii exonuclease III APE 0.0019 0.0081 0.0081
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0019 0.0081 0.0081
Mycobacterium tuberculosis Conserved protein 0.0035 0.0231 0.0762
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Brugia malayi hypothetical protein 0.0014 0.0031 0.0031
Brugia malayi ecdysone receptor 0.0014 0.0031 0.0031
Onchocerca volvulus Chorion peroxidase homolog 0.0143 0.1241 0.2632
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Toxoplasma gondii beta tubulin 0.1079 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0031 0.0031
Trichomonas vaginalis abcb9, putative 0.0021 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0041 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.024 0.024
Mycobacterium ulcerans putative regulatory protein 0.0177 0.1553 0.5815
Echinococcus granulosus neuroglian 0.0015 0.0038 0.0038
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0012 0.001 0.001
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0375 0.3406 0.3406
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0097 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0231 0.0231
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0123 0.0221
Schistosoma mansoni tyrosine kinase 0.008 0.0652 0.0652
Schistosoma mansoni nck2/grb4 0.002 0.0082 0.0082
Trichomonas vaginalis tubulin gamma chain, putative 0.0591 0.5425 0.5425
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0263 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0177 0.0177
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0099 0.0827 0.0827
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0231 0.0762
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Echinococcus multilocularis tubulin epsilon chain 0.0591 0.5425 0.5425
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.1434 0.1434
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Echinococcus multilocularis Tubulin beta 2C chain 0.1079 1 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.002 0.002
Schistosoma mansoni alpha tubulin 0.0812 0.7498 0.7498
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0219 0.195 0.195
Schistosoma mansoni tubulin subunit delta 0.026 0.2332 0.2332
Echinococcus granulosus beta tubulin 0.1079 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0097 0.0097
Loa Loa (eye worm) tubulin gamma chain 0.0591 0.5425 0.5425
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Brugia malayi Fibronectin type III domain containing protein 0.0012 0.001 0.001
Schistosoma mansoni tyrosine kinase 0.0085 0.0696 0.0696
Trichomonas vaginalis tubulin, putative 0.026 0.2332 0.2332
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0039 0.0263 0.0767
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0027 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.1592 0.1592
Loa Loa (eye worm) hypothetical protein 0.002 0.0082 0.0082
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Toxoplasma gondii alpha tubulin TUBA1 0.0812 0.7498 0.7498
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0031 0.0031
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0331 0.2992 0.2992
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0046
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0085 0.0696 0.0696
Echinococcus multilocularis Immunoglobulin 0.0012 0.001 0.001
Schistosoma mansoni growth factor receptor-bound protein 0.002 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0039 0.0263 0.0767
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0327 0.0327
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0039 0.0263 0.0263
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0123 0.0221
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.0388 0.0388
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0371 0.0371
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0213 0.1895 0.8078
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0464 0.0464
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0177 0.0177
Schistosoma mansoni notch 0.0034 0.0221 0.0221
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0034 0.0216 0.0449
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0046 0.0327 0.0327
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0148 0.0148
Echinococcus granulosus chromobox protein 1 0.0068 0.0538 0.0538
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0039 0.0263 0.0901
Loa Loa (eye worm) tubulin alpha 2 0.0552 0.5066 0.5066
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Onchocerca volvulus 0.0238 0.2125 0.4512
Brugia malayi bHLH-PAS transcription factor 0.0177 0.1553 0.1553
Loa Loa (eye worm) hypothetical protein 0.005 0.0364 0.0364
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0081 0.0081
Brugia malayi glutaminase DH11.1 0.0291 0.2622 0.2622
Toxoplasma gondii DNA topoisomerase I, putative 0.019 0.1676 0.1676
Echinococcus multilocularis tyrosine protein kinase Abl 0.0183 0.1612 0.1612
Brugia malayi Cadherin domain containing protein 0.0034 0.0216 0.0216
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0364 0.0364
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0097 0.0097
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0015 0.0036 0.0036
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0097 0.0097
Schistosoma mansoni loxhd1 0.0019 0.0081 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0039 0.0263 0.0901
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0213 0.1895 0.8078
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0231 0.0762
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0231 0.0231
Leishmania major epsilon tubulin, putative 0.0591 0.5425 0.5425
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0153 0.0153
Entamoeba histolytica Ran family GTPase 0.0021 0.0095 0.0095
Schistosoma mansoni laminin gamma-3 chain 0.0034 0.0216 0.0216
Leishmania major beta tubulin 0.1079 1 1
Trypanosoma brucei alpha tubulin 0.0812 0.7498 0.7498
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0046 0.0327 0.031
Plasmodium falciparum glutathione reductase 0.0032 0.0203 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Echinococcus granulosus Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0047 0.0047
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0177 0.0177
Brugia malayi beta-lactamase 0.0035 0.0231 0.0231
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0123 0.0123
Onchocerca volvulus 0.0015 0.0036 0.0068
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0039 0.0263 0.0767
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0039 0.0263 0.0767
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Echinococcus granulosus roundabout 2 0.0015 0.0038 0.0038
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Trichomonas vaginalis tubulin epsilon chain, putative 0.1079 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.018
Trypanosoma cruzi tubulin delta chain 0.026 0.2332 0.2319
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0552 0.5066 0.5066
Schistosoma mansoni nephrin 0.0015 0.0038 0.0038
Echinococcus multilocularis protein jagged 2 0.0034 0.0216 0.0216
Echinococcus multilocularis Immunoglobulin 0.0012 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0298 0.0298
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.1458 0.3092
Leishmania major cytochrome p450-like protein 0.0039 0.0263 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0177 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0231 0.0214
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0046 0.0046
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Brugia malayi Variant SH3 domain containing protein 0.002 0.0082 0.0082
Schistosoma mansoni thyroid hormone receptor 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0073 0.0073
Onchocerca volvulus 0.0095 0.0787 0.1666
Echinococcus multilocularis Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0036 0.0036
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1458 0.1458
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0123 0.0123
Brugia malayi notch-like transmembrane receptor 0.0034 0.0216 0.0216
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.002 0.002
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0177 0.0177
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0024 0.0126 0.0126
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0993 0.0993
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0213 0.1895 0.8078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0327 0.0327
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0319 0.0319
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Giardia lamblia Hypothetical protein 0.0046 0.0327 0.0248
Echinococcus multilocularis bloom syndrome protein 0.0023 0.012 0.012
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0231 0.0231
Trypanosoma cruzi tubulin gamma chain 0.0591 0.5425 0.5417
Schistosoma mansoni multidrug resistance protein 0.0021 0.0097 0.0097
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.0388 0.0388
Echinococcus multilocularis neural cadherin 0.0034 0.0216 0.0216
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0097 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0319 0.0319
Entamoeba histolytica hypothetical protein 0.0046 0.0329 0.0329
Entamoeba histolytica modulator of drug activity B homolog, putative 0.006 0.0464 0.0464
Plasmodium falciparum alpha tubulin 1 0.0812 0.7498 0.7498
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0046 0.0046
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0123 0.0221
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0046 0.0327 0.0327
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0081 0.0081
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.185 0.185
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0223 0.0223
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0039 0.0263 0.0767
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0223 0.0206
Schistosoma mansoni hypothetical protein 0.0041 0.0283 0.0283
Onchocerca volvulus 0.0034 0.0216 0.0449
Echinococcus granulosus DNA topoisomerase 1 0.019 0.1676 0.1676
Echinococcus multilocularis tubulin gamma 1 chain 0.0591 0.5425 0.5425
Loa Loa (eye worm) hypothetical protein 0.0034 0.0216 0.0216
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0371 0.1378
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Onchocerca volvulus Slit protein homolog 0.0034 0.0216 0.0449
Brugia malayi Tubulin gamma chain 0.0591 0.5425 0.5425
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0292 0.2632 0.2632
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0097 0.0097
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0216 0.0216
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0177 0.0177
Echinococcus granulosus Chromobox protein 3 0.0011 0.0004 0.0004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0105 0.0879 0.0879
Echinococcus granulosus Ankyrin 0.0015 0.0039 0.0039
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.024 0.024
Trichomonas vaginalis tubulin beta-1 chain, putative 0.026 0.2332 0.2332
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0039 0.0263 0.0767
Echinococcus granulosus neural cadherin 0.0034 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0328 0.2965 0.2965
Leishmania major carbonic anhydrase-like protein 0.0513 0.4695 0.4695
Schistosoma mansoni hypothetical protein 0.0034 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Mycobacterium leprae Probable lipase LipE 0.0035 0.0231 0.0488
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.024 0.024
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0097 0.0097
Onchocerca volvulus 0.005 0.0364 0.0765
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0039 0.0263 0.0767
Schistosoma mansoni ran 0.0021 0.0095 0.0095
Trichomonas vaginalis tubulin, putative 0.1079 1 1
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Echinococcus multilocularis tubulin alpha 0.0591 0.5425 0.5425
Echinococcus multilocularis 0.0039 0.0263 0.0263
Mycobacterium ulcerans lipase LipD 0.0035 0.0231 0.0642
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0231 0.0642
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0143 0.1241 0.1241
Plasmodium falciparum tubulin delta chain, putative 0.026 0.2332 0.2332
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0039 0.0263 0.0767
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Trypanosoma cruzi epsilon tubulin, putative 0.0591 0.5425 0.5417
Loa Loa (eye worm) hypothetical protein 0.0046 0.0327 0.0327
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0095 0.0095
Schistosoma mansoni tyrosine kinase 0.0052 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0035 0.0231 0.0231
Schistosoma mansoni tyrosine kinase 0.008 0.0652 0.0652
Schistosoma mansoni cytochrome P450 0.0039 0.0263 0.0263
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.024 0.024
Trichomonas vaginalis tubulin beta chain, putative 0.0331 0.2992 0.2992
Schistosoma mansoni cpg binding protein 0.0031 0.0186 0.0186
Toxoplasma gondii alpha-tubulin I, putative 0.0812 0.7498 0.7498
Schistosoma mansoni hypothetical protein 0.0412 0.3751 0.3751
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Loa Loa (eye worm) carbonic anhydrase 3 0.0513 0.4695 0.4695
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0046 0.0327 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.2156 0.2156
Echinococcus granulosus tyrosine protein kinase HCK 0.0034 0.022 0.022
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0039 0.0263 0.0767
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0066 0.0066
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0062 0.048 0.0464
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.048 0.048
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.2274 0.2274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.024 0.0223
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0081 0.0081
Leishmania major cytochrome p450-like protein 0.0039 0.0263 0.0263
Loa Loa (eye worm) animal heme peroxidase 0.0143 0.1241 0.1241
Schistosoma mansoni peroxidasin 0.0143 0.1241 0.1241
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0231 0.0214
Schistosoma mansoni tubulin subunit alpha 0.0812 0.7498 0.7498
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.024 0.024
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0123 0.0123
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0407 0.0407
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0203 0.0203
Loa Loa (eye worm) glutaminase 0.0291 0.2622 0.2622
Echinococcus multilocularis aryl hydrocarbon receptor 0.0516 0.4723 0.4723
Mycobacterium leprae Conserved hypothetical protein 0.0039 0.0263 0.0632
Brugia malayi Protein kinase domain containing protein 0.0014 0.0033 0.0033
Schistosoma mansoni tubulin subunit gamma 0.0591 0.5425 0.5425
Loa Loa (eye worm) hypothetical protein 0.0163 0.1429 0.1429
Trypanosoma brucei alpha tubulin 0.0812 0.7498 0.7498
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0327 0.0327
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0193 0.0193
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0064 0.05 0.05
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0403 0.0403
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.024 0.024
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0123 0.0123
Echinococcus granulosus geminin 0.0669 0.6162 0.6162
Brugia malayi Death domain containing protein 0.0014 0.0033 0.0033
Trichomonas vaginalis tubulin epsilon chain, putative 0.0812 0.7498 0.7498
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0223 0.0223
Schistosoma mansoni cpg binding protein 0.0031 0.0186 0.0186
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0317 0.2866 0.2866
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0231 0.0762
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0064 0.05 0.05
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0123 0.0221
Loa Loa (eye worm) tubulin beta chain 0.1079 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0619 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.043 0.3921 0.3921
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0097 0.0097
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0185 0.0185
Trichomonas vaginalis tubulin alpha chain, putative 0.0331 0.2992 0.2992
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0038
Echinococcus multilocularis thioredoxin glutathione reductase 0.0093 0.0775 0.0775
Leishmania major beta tubulin 0.1079 1 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0046 0.0327 0.0327
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0263 0.0263
Trypanosoma brucei epsilon tubulin 0.0591 0.5425 0.5425
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0046
Schistosoma mansoni importin beta-1 0.0057 0.0429 0.0429
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0034 0.0216 0.0216
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0269 0.0269
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Toxoplasma gondii hypothetical protein 0.0026 0.0148 0.0148
Schistosoma mansoni tubulin subunit beta 0.1079 1 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0031 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0292 0.2632 0.2632
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0039 0.0263 0.0901
Loa Loa (eye worm) glutathione reductase 0.0093 0.0775 0.0775
Leishmania major beta tubulin 0.1079 1 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0203 0.0533
Loa Loa (eye worm) hypothetical protein 0.0146 0.1269 0.1269
Brugia malayi ABC transporter family protein 0.0021 0.0097 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1541 0.1541
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0177 0.0177
Leishmania major alpha tubulin 0.0812 0.7498 0.7498
Mycobacterium tuberculosis Conserved protein 0.0035 0.0231 0.0762
Giardia lamblia Beta tubulin 0.1079 1 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0203 0.0186
Loa Loa (eye worm) tubulin beta-4 chain 0.1079 1 1
Brugia malayi tubulin alpha-2 chain 0.0812 0.7498 0.7498
Echinococcus multilocularis snurportin 1 0.0604 0.5548 0.5548
Trypanosoma brucei carbonic anhydrase-like protein 0.0513 0.4695 0.4695
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0046 0.0327 0.0327
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0039 0.0263 0.0901
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0203 0.0186
Brugia malayi ecdysteroid receptor 0.003 0.0177 0.0177
Echinococcus multilocularis Tubulin alpha 1 chain 0.0812 0.7498 0.7498
Brugia malayi nuclear receptor RXR 0.0014 0.0031 0.0031
Toxoplasma gondii thioredoxin reductase 0.0093 0.0775 0.0775
Loa Loa (eye worm) beta-tubulin 0.1079 1 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0513 0.4695 0.4686
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0177 0.0368
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0177 0.0177
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0148 0.0261
Schistosoma mansoni patched 1 0.0043 0.0298 0.0298
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.017 0.017
Loa Loa (eye worm) TK protein kinase 0.0034 0.022 0.022
Echinococcus multilocularis beta tubulin 0.1079 1 1
Schistosoma mansoni lipoxygenase 0.0054 0.0407 0.0407
Plasmodium vivax delta tubulin, putative 0.026 0.2332 0.2332
Brugia malayi nuclear receptor NHR-88 0.003 0.0177 0.0177
Onchocerca volvulus 0.0292 0.2632 0.5591
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0375 0.3406 0.3406
Plasmodium vivax amine transporter, putative 0.005 0.0364 0.0364
Echinococcus granulosus tyrosine kinase 0.0015 0.0036 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0093 0.0775 0.0759
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0123 0.0221
Loa Loa (eye worm) sex muscle abnormal protein 5 0.002 0.0082 0.0082
Trichomonas vaginalis tubulin beta chain, putative 0.0812 0.7498 0.7498
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.001
Echinococcus multilocularis c src tyrosine kinase 0.0024 0.0126 0.0126
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0046 0.0327 0.031
Trichomonas vaginalis modulator of drug activity B, putative 0.006 0.0464 0.0464
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0203 0.0186
Onchocerca volvulus Putative cubilin 0.0034 0.0216 0.0449
Schistosoma mansoni notch 0.0034 0.0216 0.0216
Schistosoma mansoni tyrosine kinase 0.0085 0.0696 0.0696
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0031 0.0031
Schistosoma mansoni nuclear receptor 0.0014 0.0031 0.0031
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0327 0.031
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0004
Brugia malayi Pre-SET motif family protein 0.003 0.0185 0.0185
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0027 0.0027
Mycobacterium ulcerans beta-lactamase 0.0035 0.0231 0.0642
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0403 0.0403
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0033 0.0033
Leishmania major alpha tubulin 0.0812 0.7498 0.7498

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 22 nM Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation counting ChEMBL. 25050161
IC50 (binding) = 29 nM Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation counting ChEMBL. 25050161
IC50 (binding) = 43 nM Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation counting ChEMBL. 25050161

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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