Detailed information for compound 1563511

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 791.926 | Formula: C36H65N5O14
  • H donors: 8 H acceptors: 9 LogP: 0.7 Rotable bonds: 29
    Rule of 5 violations (Lipinski): 3
  • SMILES: COC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)CCOC[C@H]1O[C@@H](OCCNC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C)[C@@H]([C@H]([C@@H]1O)O)O)CC(C)C
  • InChi: 1S/C36H65N5O14/c1-18(2)16-22(33(49)51-11)39-32(48)26(20(5)6)40-24(42)12-14-52-17-23-27(43)28(44)29(45)34(54-23)53-15-13-37-31(47)25(19(3)4)41-30(46)21(7)38-35(50)55-36(8,9)10/h18-23,25-29,34,43-45H,12-17H2,1-11H3,(H,37,47)(H,38,50)(H,39,48)(H,40,42)(H,41,46)/t21-,22-,23+,25-,26-,27+,28-,29+,34+/m0/s1
  • InChiKey: DIVVWVXKDQTUNK-UEBPAERWSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like cysteine proteinase 0.0321 0.214 0.214
Onchocerca volvulus 0.0104 0.0627 0.1941
Leishmania major beta tubulin 0.0167 0.107 0.296
Schistosoma mansoni biogenic amine receptor 0.0038 0.0166 0.0166
Toxoplasma gondii exonuclease III APE 0.0028 0.0097 0.0187
Trypanosoma brucei beta tubulin 0.0167 0.107 0.296
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0166 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Entamoeba histolytica hypothetical protein 0.0024 0.0069 0.0196
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Brugia malayi hypothetical protein 0.007 0.0394 0.0394
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Giardia lamblia Encystation-specific protease 0.0118 0.0728 0.1957
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi excitatory GABA receptor EXP-1A 0.0145 0.0914 0.0914
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0057 0.0057
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0118 0.0728 0.2271
Plasmodium falciparum proteasome subunit beta type-5 0.0069 0.0384 0.1151
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis maltase-glucoamylase, putative 0.0019 0.0038 0.0084
Echinococcus multilocularis small conductance calcium activated potassium 0.019 0.123 0.123
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0181 0.0372
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1448 1 1
Echinococcus granulosus proteasome prosome macropain 0.0069 0.0384 0.0384
Echinococcus multilocularis voltage gated potassium channel 0.0025 0.0079 0.0079
Echinococcus multilocularis tubulin delta chain 0.0038 0.0171 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Entamoeba histolytica tubulin gamma chain 0.0088 0.0519 0.165
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0069 0.0384 0.0992
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0028 0.0097 0.0097
Giardia lamblia Cathepsin B precursor 0.053 0.3596 1
Brugia malayi Ets-domain containing protein 0.0047 0.0231 0.0231
Brugia malayi neuropeptide F receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0171 0.0453
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0022 0.006 0.0097
Echinococcus granulosus Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0728 0.0728
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0627 0.0627
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0181 0.0173
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0321 0.214 0.5943
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.02 0.02
Echinococcus granulosus neuropeptide receptor 0.0038 0.0166 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0025 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Plasmodium vivax vivapain-2 0.0459 0.3103 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) voltage-gated calcium channel 0.0025 0.0079 0.0079
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Echinococcus multilocularis dihydrofolate reductase 0.005 0.0249 0.0249
Plasmodium falciparum glutathione reductase 0.0022 0.006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Brugia malayi Melatonin receptor type 1A 0.0038 0.0166 0.0166
Echinococcus granulosus acetylcholinesterase 0.0053 0.0274 0.0274
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0075 0.0424 0.0424
Leishmania major beta tubulin 0.0167 0.107 0.296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Toxoplasma gondii hypothetical protein 0.0019 0.0035 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Schistosoma mansoni transient receptor potential channel 0.0025 0.0079 0.0079
Trichomonas vaginalis tubulin beta chain, putative 0.0167 0.107 0.296
Brugia malayi Papain family cysteine protease containing protein 0.0459 0.3103 0.3103
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Echinococcus multilocularis Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Brugia malayi beta-tubulin, identical 0.0167 0.107 0.107
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0145 0.0914 0.0914
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Plasmodium vivax tubulin epsilon chain, putative 0.0088 0.0519 0.159
Trypanosoma brucei tubulin delta chain 0.0038 0.0171 0.0453
Plasmodium falciparum serine repeat antigen 5 0.0118 0.0728 0.2271
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0459 0.3103 0.3103
Loa Loa (eye worm) CYP4Cod1 0.0082 0.0479 0.0479
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0333
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0024 0.0069 0.0069
Trichomonas vaginalis hypothetical protein 0.0019 0.0035 0.0075
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Echinococcus multilocularis microtubule associated protein 2 0.0732 0.5005 0.5005
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0097 0.0248
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0506 0.3429 0.3429
Schistosoma mansoni hypothetical protein 0.019 0.123 0.123
Brugia malayi ion channel NompC 0.0025 0.0079 0.0079
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0145 0.0914 0.0914
Schistosoma mansoni peroxidasin 0.0104 0.0627 0.0627
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0364 0.2442 0.2442
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.006 0.0052
Onchocerca volvulus 0.0459 0.3103 1
Leishmania major beta tubulin 0.0167 0.107 0.296
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0927
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Echinococcus granulosus peroxidasin 0.0104 0.0627 0.0627
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni calpain-7 (C02 family) 0.0065 0.0354 0.0354
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) calpain D 0.0019 0.0035 0.0035
Brugia malayi Papain family cysteine protease containing protein 0.0256 0.1691 0.1691
Echinococcus multilocularis transfer RNA-Lys 0.0027 0.009 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0728 0.0728
Trypanosoma cruzi cysteine protease, putative 0.0256 0.1691 0.1684
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0359 0.0359
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Giardia lamblia Cathepsin L-like protease 0.0118 0.0728 0.1957
Loa Loa (eye worm) hypothetical protein 0.1448 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0016 0.0019 0.0019
Loa Loa (eye worm) cytochrome P450 0.004 0.0181 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0.0079 0.0079
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0145 0.0914 0.0914
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0171 0.1096 0.3033
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi hypothetical protein 0.0087 0.0508 0.0508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.007 0.0394 0.0394
Mycobacterium tuberculosis Probable dehydrogenase 0.0148 0.0934 0.223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0134 0.0256
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0103 0.0103
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0134 0.1018
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0118 0.0728 0.2271
Leishmania major pyruvate kinase 0.0035 0.015 0.0396
Loa Loa (eye worm) hypothetical protein 0.0138 0.0867 0.0867
Giardia lamblia Cathepsin B precursor 0.0118 0.0728 0.1957
Giardia lamblia Cathepsin B precursor 0.053 0.3596 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0145 0.0914 0.0914
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Entamoeba histolytica tubulin family protein 0.0167 0.107 0.3431
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0145 0.0914 0.0914
Echinococcus granulosus somatostatin receptor 0.0038 0.0166 0.0166
Echinococcus granulosus cathepsin L cysteine proteinase 0.0459 0.3103 0.3103
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0728 0.0728
Entamoeba histolytica calpain family cysteine protease, putative 0.0019 0.0035 0.0087
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0161 0.0493
Echinococcus granulosus tubulin subunit TubB 0.0121 0.0746 0.0746
Plasmodium vivax pyruvate kinase, putative 0.0035 0.015 0.0391
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0181 0.0372
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Echinococcus multilocularis pyruvate kinase 0.0018 0.003 0.003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0041 0.0189 0.0189
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0166 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0246 0.0703
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0031 0.012 0.012
Onchocerca volvulus 0.0076 0.0434 0.1314
Echinococcus multilocularis calpain A 0.0174 0.1115 0.1115
Echinococcus multilocularis calpain 0.0063 0.0341 0.0341
Entamoeba histolytica cysteine proteinase, putative 0.0256 0.1691 0.5437
Echinococcus granulosus nAChR subunit 0.0145 0.0914 0.0914
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0022 0.006 0.0074
Schistosoma mansoni opsin-like receptor 0.0038 0.0166 0.0166
Trypanosoma brucei polo-like protein kinase 0.005 0.0256 0.0689
Echinococcus granulosus glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Trichomonas vaginalis tubulin alpha chain, putative 0.0167 0.107 0.296
Entamoeba histolytica tubulin alpha chain, putative 0.0121 0.0746 0.2383
Brugia malayi hypothetical protein 0.007 0.0394 0.0394
Schistosoma mansoni voltage-dependent calcium channel 0.0025 0.0079 0.0079
Leishmania major beta tubulin 0.0167 0.107 0.296
Echinococcus multilocularis tubulin alpha chain 0.0121 0.0746 0.0746
Onchocerca volvulus 0.007 0.0394 0.1182
Echinococcus multilocularis calpain family protein 1, d 0.0122 0.0757 0.0757
Onchocerca volvulus 0.007 0.0394 0.1182
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0.0079 0.0079
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0256 0.1691 0.1691
Brugia malayi calpain D 0.0019 0.0035 0.0035
Schistosoma mansoni inositol monophosphatase 0.0037 0.0161 0.0161
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0246 0.0664
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0166 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.012 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0121 0.0746 0.2056
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Entamoeba histolytica hypothetical protein 0.0024 0.0069 0.0196
Brugia malayi cation channel family protein 0.0025 0.0079 0.0079
Trypanosoma brucei hypothetical protein, conserved 0.0094 0.0558 0.1532
Plasmodium falciparum cysteine proteinase falcipain 3 0.0459 0.3103 1
Trypanosoma brucei cytochrome P450, putative 0.0082 0.0479 0.1311
Brugia malayi sulfakinin receptor protein 0.0038 0.0166 0.0166
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0127 0.033
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0394 0.0394
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.015 0.0337
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Schistosoma mansoni transient receptor potential channel 0.0025 0.0079 0.0079
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0174 0.1115 0.1115
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0028 0.0097 0.0187
Entamoeba histolytica tubulin family protein 0.0167 0.107 0.3431
Plasmodium vivax delta tubulin, putative 0.0038 0.0171 0.0457
Echinococcus multilocularis potassium large conductance calcium activated 0.0025 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0042 0.02 0.02
Brugia malayi tubulin alpha chain - mouse 0.0121 0.0746 0.0746
Trypanosoma brucei trypanothione reductase 0.0065 0.0355 0.0967
Echinococcus multilocularis cysteine protease 0.0459 0.3103 0.3103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus two pore calcium channel protein 1 0.0025 0.0079 0.0079
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0127 0.033
Echinococcus multilocularis tubulin alpha 1C chain 0.0121 0.0746 0.0746
Echinococcus multilocularis expressed protein 0.0266 0.1755 0.1755
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0181 0.2089
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.003 0.0062
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.002 0.004 0.0089
Brugia malayi hypothetical protein 0.0099 0.0597 0.0597
Onchocerca volvulus 0.0145 0.0914 0.2875
Schistosoma mansoni intermediate filament proteins 0.0076 0.0434 0.0434
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0519 0.1424
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0.0079 0.0079
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0094 0.0558 0.732
Echinococcus granulosus sodium leak channel non selective protein 0.0025 0.0079 0.0079
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0097 0.0217
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0082 0.0479 0.1311
Schistosoma mansoni single-minded 0.0036 0.0155 0.0155
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0077 0.0442 0.0442
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1448 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0145 0.0914 0.0914
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0028 0.0097 0.0097
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0341 0.0927
Echinococcus multilocularis tubulin gamma 1 chain 0.0088 0.0519 0.0519
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0181 0.2089
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0307 0.0832
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0171 0.0163
Loa Loa (eye worm) tubulin beta chain 0.0167 0.107 0.107
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0097 0.0248
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0181 0.2089
Brugia malayi thymidylate synthase 0.0122 0.0751 0.0751
Giardia lamblia Cathepsin B precursor 0.0118 0.0728 0.1957
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0058 0.031 0.0785
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0019 0.0035 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Echinococcus multilocularis tubulin epsilon chain 0.0088 0.0519 0.0519
Onchocerca volvulus 0.0038 0.0166 0.0442
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0394 0.0394
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0252 0.0679
Entamoeba histolytica hypothetical protein 0.0118 0.0728 0.2326
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Entamoeba histolytica cysteine proteinase, putative 0.0321 0.214 0.6889
Echinococcus granulosus dihydrofolate reductase 0.005 0.0249 0.0249
Schistosoma mansoni hypothetical protein 0.0024 0.0069 0.0069
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.015 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0256 0.1691 0.4691
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0166 0.0166
Schistosoma mansoni alpha tubulin 0.0121 0.0746 0.0746
Brugia malayi alpha-tubulin 0.0121 0.0746 0.0746
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0078 0.0194
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0118 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0036 0.0158 0.0158
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0927
Echinococcus multilocularis calcium activated potassium channel 0.0025 0.008 0.008
Plasmodium vivax vivapain-3 0.0256 0.1691 0.5404
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0019 0.0038 0.0038
Echinococcus granulosus calcium activated potassium channel 0.0025 0.008 0.008
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0728 0.2271
Onchocerca volvulus Chorion peroxidase homolog 0.0104 0.0627 0.1941
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0118 0.0728 0.2271
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0103 0.0103
Entamoeba histolytica cysteine proteinase 1, putative 0.0256 0.1691 0.5437
Mycobacterium ulcerans beta-lactamase 0.0094 0.0558 0.732
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Mycobacterium ulcerans hypothetical protein 0.0094 0.0558 0.732
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0148 0.0934 0.223
Echinococcus multilocularis tubulin alpha 1C chain 0.0121 0.0746 0.0746
Plasmodium vivax tubulin alpha chain, putative 0.0121 0.0746 0.2328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Onchocerca volvulus 0.0459 0.3103 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0728 0.2007
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0.0079 0.0079
Plasmodium falciparum cysteine proteinase falcipain 1 0.0256 0.1691 0.5404
Plasmodium falciparum serine repeat antigen 7 0.0118 0.0728 0.2271
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0103 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Trichomonas vaginalis esterase, putative 0.0094 0.0558 0.1532
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0.0079 0.0079
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0181 0.0372
Brugia malayi Cation transporter family protein 0.0145 0.0914 0.0914
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0.0079 0.0079
Mycobacterium ulcerans esterase/lipase LipP 0.0094 0.0558 0.732
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis nAChR subunit 0.0075 0.0424 0.0424
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Onchocerca volvulus 0.0145 0.0914 0.2875
Trichomonas vaginalis glucosylceramidase, putative 0.0127 0.0787 0.2171
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.015 0.1179
Schistosoma mansoni ryanodine receptor related 0.0025 0.0079 0.0079
Schistosoma mansoni tubulin subunit alpha 0.0121 0.0746 0.0746
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0.0079 0.0079
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Echinococcus multilocularis two pore calcium channel protein 1 0.0025 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Brugia malayi hypoxia-induced factor 1 0.0112 0.0681 0.0681
Echinococcus multilocularis Tubulin beta 2C chain 0.0167 0.107 0.107
Brugia malayi cathepsin F-like cysteine proteinase 0.0118 0.0728 0.0728
Onchocerca volvulus 0.0038 0.0166 0.0442
Loa Loa (eye worm) hypothetical protein 0.0147 0.0931 0.0931
Toxoplasma gondii cathepsin CPC1 0.0118 0.0728 0.1957
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Echinococcus multilocularis Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Plasmodium falciparum thioredoxin reductase 0.0022 0.006 0.0097
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0094 0.0558 0.0558
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0166 0.0166
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0025 0.0079 0.0079
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0069 0.0384 0.0376
Echinococcus multilocularis lamin dm0 0.0076 0.0434 0.0434
Schistosoma mansoni kinase 0.0026 0.0083 0.0083
Loa Loa (eye worm) tubulin alpha-3 chain 0.0071 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0145 0.0914 0.0914
Entamoeba histolytica cysteine proteinase 2 0.0256 0.1691 0.5437
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Echinococcus granulosus calpain A 0.0174 0.1115 0.1115
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0103 0.0103
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.015 0.0142
Echinococcus multilocularis geminin 0.0648 0.4423 0.4423
Echinococcus multilocularis Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Echinococcus granulosus pyruvate kinase 0.0018 0.003 0.003
Schistosoma mansoni biogenic amine receptor 0.0038 0.0166 0.0166
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0022 0.006 0.006
Schistosoma mansoni calpain (C02 family) 0.0063 0.0341 0.0341
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0038 0.0084
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0166 0.0166
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0118 0.0728 0.2271
Echinococcus multilocularis cathepsin L 0.0256 0.1691 0.1691
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0037 0.016 0.016
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0166 0.0166
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0728 0.2271
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0728 0.0728
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0076 0.0076
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0121 0.0746 0.0746
Schistosoma mansoni transcription factor LCR-F1 0.0024 0.0069 0.0069
Onchocerca volvulus 0.0038 0.0166 0.0442
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0071 0.0398 0.1086
Schistosoma mansoni tubulin subunit delta 0.0038 0.0171 0.0171
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0019 0.0038 0.0098
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni nAChR subunit 0.007 0.0394 0.0394
Echinococcus granulosus tubulin epsilon chain 0.0088 0.0519 0.0519
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0181 0.0372
Trypanosoma cruzi cysteine proteinase, putative 0.0256 0.1691 0.1684
Loa Loa (eye worm) hypothetical protein 0.0138 0.0867 0.0867
Giardia lamblia Histone acetyltransferase GCN5 0.0053 0.0276 0.069
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0.0079 0.0079
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0.0079 0.0079
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0161 0.0161
Trichomonas vaginalis calpain, putative 0.0019 0.0035 0.0075
Echinococcus granulosus tubulin alpha chain 0.0121 0.0746 0.0746
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0028 0.0097 0.0248
Echinococcus granulosus tubulin alpha 1C chain 0.0121 0.0746 0.0746
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.015 0.0296
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.007 0.0394 0.0394
Brugia malayi Tubulin beta-1 chain 0.0167 0.107 0.107
Echinococcus multilocularis Tubulin beta 2C chain 0.0167 0.107 0.107
Leishmania major hypothetical protein, conserved 0.0019 0.0035 0.0075
Schistosoma mansoni histamine h1 receptor 0.0038 0.0166 0.0166
Leishmania major beta tubulin 0.0167 0.107 0.296
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0076 0.0218
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0122 0.0757 0.0757
Brugia malayi cation channel family protein 0.0025 0.0079 0.0079
Schistosoma mansoni survival motor neuron protein 0.0048 0.0237 0.0237
Loa Loa (eye worm) thioredoxin reductase 0.0065 0.0355 0.0355
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0266 0.0266
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0161 0.1813
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0728 0.2007
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0519 0.0511
Trypanosoma cruzi tubulin delta chain 0.0038 0.0171 0.0163
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0153
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0166 0.0166
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0025 0.0079 0.0079
Entamoeba histolytica hypothetical protein 0.0075 0.0424 0.1343
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0359 0.0359
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.007 0.0394 0.0394
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0069 0.0384 0.0376
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0118 0.0728 0.2271
Trypanosoma brucei alpha tubulin 0.0121 0.0746 0.2056
Loa Loa (eye worm) tubulin alpha 2 0.0082 0.0479 0.0479
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0038 0.003
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0181 0.0372
Echinococcus granulosus sodium channel protein 0.0364 0.2442 0.2442
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0122 0.0751 0.1779
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0094 0.0558 0.1302
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Brugia malayi cathepsin L-like precursor 0.0321 0.214 0.214
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0166 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Entamoeba histolytica acyl-coA synthetase, putative 0.0018 0.003 0.0071
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Plasmodium vivax vivapain-1 0.0256 0.1691 0.5404
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0016 0.0019 0.0019
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0019 0.0036 0.0018
Schistosoma mansoni alpha-glucosidase 0.0075 0.0426 0.0426
Echinococcus multilocularis tubulin alpha 3 chain 0.0121 0.0746 0.0746
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0333
Echinococcus granulosus expressed protein 0.0266 0.1755 0.1755
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0103 0.0103
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0166 0.0166
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0359 0.0359
Brugia malayi Fli-1 protein 0.0142 0.0897 0.0897
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1538 0.1538
Trypanosoma cruzi beta tubulin, putative 0.0167 0.107 0.1063
Echinococcus multilocularis bloom syndrome protein 0.0028 0.0099 0.0099
Brugia malayi Tubulin alpha chain 0.0121 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0145 0.0914 0.0914
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0181 0.0372
Echinococcus multilocularis lysosomal alpha glucosidase 0.0087 0.051 0.051
Schistosoma mansoni amine GPCR 0.0038 0.0166 0.0166
Schistosoma mansoni hypothetical protein 0.0025 0.0079 0.0079
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0069 0.0384 0.3475
Schistosoma mansoni opsin-like receptor 0.0038 0.0166 0.0166
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0145 0.0914 0.0914
Brugia malayi Cation transporter family protein 0.0145 0.0914 0.0914
Schistosoma mansoni alpha-glucosidase 0.0075 0.0426 0.0426
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0166 0.0166
Echinococcus multilocularis short transient receptor potential channel 6 0.0025 0.0079 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Brugia malayi fibroinase precursor 0.0118 0.0728 0.0728
Echinococcus multilocularis cathepsin L cysteine protease 0.0459 0.3103 0.3103
Schistosoma mansoni voltage-gated ion channel 0.0025 0.0079 0.0079
Brugia malayi AMP-binding enzyme family protein 0.0018 0.003 0.003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0138 0.0867 0.0867
Schistosoma mansoni pyruvate kinase 0.0035 0.015 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Trypanosoma brucei beta tubulin 0.0167 0.107 0.296
Onchocerca volvulus Cathepsin F homolog 0.0459 0.3103 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0028 0.0097 0.0097
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0181 0.0372
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.015 0.015
Trypanosoma cruzi tubulin gamma chain 0.0088 0.0519 0.0511
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0145 0.0914 0.0914
Echinococcus multilocularis lysosomal alpha glucosidase 0.0087 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0166 0.0166
Echinococcus granulosus alpha tubulin 0.0121 0.0746 0.0746
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0161 0.9101
Loa Loa (eye worm) voltage-gated potassium channel 0.0025 0.0079 0.0079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0256 0.0256
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.005 0.0256 0.0256
Brugia malayi hypothetical protein 0.0121 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0321 0.214 0.5943
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0028 0.0097 0.3339
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Loa Loa (eye worm) tubulin alpha 2 0.0082 0.0479 0.0479
Trypanosoma brucei beta tubulin 0.0088 0.0519 0.1424
Onchocerca volvulus 0.0075 0.0424 0.1281
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Brugia malayi Tubulin beta chain 0.005 0.0252 0.0252
Loa Loa (eye worm) pyruvate kinase 0.0035 0.015 0.015
Echinococcus multilocularis lamin 0.0076 0.0434 0.0434
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0075 0.0424 0.0424
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0145 0.0914 0.0914
Leishmania major pyruvate kinase 0.0035 0.015 0.0396
Trichomonas vaginalis tubulin alpha chain, putative 0.0088 0.0519 0.1424
Onchocerca volvulus 0.0075 0.0424 0.1281
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0166 0.0166
Leishmania major cytochrome p450-like protein 0.004 0.0181 0.0481
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.015 0.0391
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Echinococcus granulosus cathepsin l cysteine peptidase 0.0459 0.3103 0.3103
Toxoplasma gondii cathepsin CPC2 0.0118 0.0728 0.1957
Schistosoma mansoni opsin-like receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0022 0.006 0.0097
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.0226 0.1477 0.1477
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0181 0.0372
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0103 0.0103
Echinococcus multilocularis beta tubulin 0.0167 0.107 0.107
Schistosoma mansoni amine GPCR 0.0038 0.0166 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis glycine receptor subunit beta 0.0145 0.0914 0.0914
Schistosoma mansoni nAChR subunit 0.007 0.0394 0.0394
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Plasmodium falciparum histone acetyltransferase GCN5 0.0053 0.0276 0.08
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Trypanosoma brucei calpain, putative 0.0019 0.0035 0.0075
Schistosoma mansoni cathepsin S (C01 family) 0.0118 0.0728 0.0728
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0069 0.0384 0.1048
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni calpain C (C02 family) 0.0063 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0053 0.0274 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0078 0.0194
Toxoplasma gondii thioredoxin reductase 0.0065 0.0355 0.0911
Onchocerca volvulus Peroxidasin homolog 0.0104 0.0627 0.1941
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis serotonin receptor 0.0202 0.1312 0.1312
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.005 0.0249 0.215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0239 0.0239
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0229 0.1499 0.1499
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0359 0.0359
Giardia lamblia Kinase, PLK 0.005 0.0256 0.0632
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0019 0.0035 0.0075
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0118 0.0728 0.2271
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Schistosoma mansoni dihydrofolate reductase 0.005 0.0249 0.0249
Plasmodium falciparum glutathione reductase 0.0065 0.0355 0.1057
Loa Loa (eye worm) tubulin alpha chain 0.0121 0.0746 0.0746
Echinococcus granulosus calpain 0.0063 0.0341 0.0341
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) tubulin beta chain 0.0038 0.0171 0.0171
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Leishmania major beta tubulin 0.0167 0.107 0.296
Echinococcus multilocularis calpain 5 0.0063 0.0341 0.0341
Onchocerca volvulus 0.0122 0.0751 0.2345
Trichomonas vaginalis tubulin, putative 0.005 0.0252 0.0679
Giardia lamblia Cathepsin B precursor 0.053 0.3596 1
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Echinococcus granulosus nAChR subunit 0.0075 0.0424 0.0424
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0359 0.0359
Loa Loa (eye worm) BEN-1 protein 0.0167 0.107 0.107
Schistosoma mansoni hypothetical protein 0.0038 0.0166 0.0166
Brugia malayi Cytochrome P450 family protein 0.0082 0.0479 0.0479
Loa Loa (eye worm) RNA binding protein 0.0065 0.0359 0.0359
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0145 0.0914 0.0914
Leishmania major kinesin, putative 0.0044 0.0209 0.0561
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Echinococcus granulosus small conductance calcium activated potassium 0.019 0.123 0.123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0174 0.1115 0.1115
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Schistosoma mansoni hypothetical protein 0.004 0.0181 0.0181
Mycobacterium tuberculosis Hypothetical protein 0.0058 0.0307 0.0682
Loa Loa (eye worm) carboxylesterase 0.0053 0.0274 0.0274
Brugia malayi TAR-binding protein 0.0065 0.0359 0.0359
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Echinococcus granulosus Tubulin beta 2C chain 0.0167 0.107 0.107
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0229 0.1499 0.1499
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0035 0.015 0.015
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0042 0.02 0.02
Onchocerca volvulus 0.0104 0.0627 0.1941
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0181 0.0173
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni Mername-AA248 (C02 family) 0.0063 0.0341 0.0341
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Toxoplasma gondii alpha-tubulin I, putative 0.0121 0.0746 0.2007
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0103 0.0103
Plasmodium vivax glutathione reductase, putative 0.0065 0.0355 0.1057
Entamoeba histolytica protein kinase, putative 0.0044 0.0211 0.0654
Loa Loa (eye worm) ion channel NompC 0.0025 0.0079 0.0079
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0166 0.0166
Echinococcus granulosus Tubulin beta 2C chain 0.0167 0.107 0.107
Echinococcus granulosus histone acetyltransferase KAT2B 0.0058 0.031 0.031
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0166 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0025 0.0079 0.0079
Onchocerca volvulus 0.0337 0.225 0.7224
Echinococcus multilocularis tubulin alpha chain 0.0121 0.0746 0.0746
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Loa Loa (eye worm) cytochrome P450 family protein 0.012 0.0742 0.0742
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0.0079 0.0079
Schistosoma mansoni tubulin subunit alpha 0.0038 0.0171 0.0171
Trypanosoma cruzi cysteine peptidase, putative 0.0459 0.3103 0.3098
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0022 0.006 0.0415
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0166 0.0166
Leishmania major beta tubulin 0.0167 0.107 0.296
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0166 0.0166
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0535 0.3633 0.3633
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0096 0.0096
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0174 0.1115 0.1115
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0031 0.012 0.012
Giardia lamblia Cysteine protease 0.0118 0.0728 0.1957
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0341 0.0927
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0728 0.0728
Leishmania major hypothetical protein, conserved 0.0049 0.0246 0.0664
Leishmania major trypanothione reductase 0.0065 0.0355 0.0967
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Echinococcus multilocularis pyruvate kinase 0.0018 0.003 0.003
Plasmodium falciparum serine repeat antigen 2 0.0118 0.0728 0.2271
Onchocerca volvulus Glucosylceramidase homolog 0.012 0.0742 0.2316
Brugia malayi AMP-binding enzyme family protein 0.0018 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0035 0.015 0.015
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0145 0.0914 0.0914
Chlamydia trachomatis pyruvate kinase 0.0035 0.015 0.477
Onchocerca volvulus 0.0038 0.0166 0.0442
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Leishmania major proteasome beta 5 subunit, putative 0.0069 0.0384 0.1048
Echinococcus multilocularis hypothetical protein 0.0063 0.0341 0.0341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Brugia malayi Carboxylesterase family protein 0.0053 0.0274 0.0274
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0122 0.0751 0.7077
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0122 0.0751 0.0751
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0333
Echinococcus multilocularis proteasome (prosome, macropain) 0.0069 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0202 0.1312 0.1312
Onchocerca volvulus Putative nachr subunit 0.0145 0.0914 0.2875
Brugia malayi olfactory channel protein osm-9 0.0025 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0181 0.0372
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) tubulin beta-1 chain 0.0167 0.107 0.107
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Echinococcus granulosus calpain A 0.0063 0.0341 0.0341
Echinococcus granulosus g protein coupled receptor 0.0038 0.0166 0.0166
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0256 0.1691 0.1691
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Giardia lamblia Cathepsin B precursor 0.0118 0.0728 0.1957
Entamoeba histolytica cysteine proteinase, putative 0.0459 0.3103 1
Brugia malayi G-protein coupled receptor 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0094 0.0558 0.1716
Brugia malayi GnHR receptor homolog 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin epsilon chain, putative 0.0167 0.107 0.296
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0171 0.1096 0.1089
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Plasmodium vivax SET domain protein, putative 0.0042 0.02 0.055
Giardia lamblia Cathepsin B precursor 0.0118 0.0728 0.1957
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0164 0.1048 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0181 0.2089
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0728 0.0728
Trichomonas vaginalis penicillin-binding protein, putative 0.0094 0.0558 0.1532
Trichomonas vaginalis tubulin gamma chain, putative 0.0038 0.0171 0.0453
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0181 0.2089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Onchocerca volvulus Cathepsin L homolog 0.0118 0.0728 0.2271
Echinococcus granulosus short transient receptor potential channel 6 0.0025 0.0079 0.0079
Trichomonas vaginalis set domain proteins, putative 0.0337 0.225 0.625
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0166 0.0166
Echinococcus granulosus tubulin alpha 1C chain 0.0121 0.0746 0.0746
Onchocerca volvulus 0.0038 0.0166 0.0442
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0103
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0166 0.0166
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0025 0.0079 0.0079
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0025 0.0079 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0239 0.0239
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0094 0.0558 0.0558
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Echinococcus multilocularis neutral alpha glucosidase AB 0.0019 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0.0079 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Giardia lamblia Cysteine protease 0.0118 0.0728 0.1957
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0138 0.0867 0.0867
Echinococcus multilocularis cathepsin b 0.1448 1 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0038 0.0171 1
Giardia lamblia Alpha-tubulin 0.0121 0.0746 0.2007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0166 0.0166
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0025 0.0079 0.0079
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0459 0.3103 1
Brugia malayi hypothetical protein 0.0025 0.0079 0.0079
Echinococcus granulosus Tubulin beta 2C chain 0.0167 0.107 0.107
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0927
Leishmania major calpain family cysteine protease-like protein 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0202 0.1312 0.1312
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0166 0.0166
Echinococcus granulosus cathepsin L cysteine protease 0.0256 0.1691 0.1691
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Trypanosoma cruzi cruzipain precursor, putative 0.0459 0.3103 0.3098
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0181 0.2089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0019 0.0038 0.0098
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0025 0.0079 0.0198
Trypanosoma cruzi cysteine proteinase, putative 0.0256 0.1691 0.1684
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0019 0.0035 0.0027
Echinococcus multilocularis 0.004 0.0181 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Schistosoma mansoni neurotransmitter gated ion channel 0.007 0.0394 0.0394
Echinococcus granulosus serotonin receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis serotonin receptor 0.0202 0.1312 0.1312
Schistosoma mansoni biogenic amine receptor 0.0038 0.0166 0.0166
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0166 0.0166
Echinococcus granulosus tubulin alpha chain 0.0121 0.0746 0.0746
Trypanosoma cruzi cysteine peptidase, putative 0.0459 0.3103 0.3098
Echinococcus multilocularis tubulin beta 1 chain 0.0167 0.107 0.107
Echinococcus granulosus lamin dm0 0.0076 0.0434 0.0434
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.003 0.0062
Brugia malayi G protein-coupled receptor 0.0038 0.0166 0.0166
Echinococcus granulosus calpain 5 0.0063 0.0341 0.0341
Leishmania major beta tubulin 0.0167 0.107 0.296
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0321 0.214 0.2134
Trypanosoma cruzi kinesin, putative 0.0044 0.0209 0.0201
Brugia malayi calpain family protein 1 0.0166 0.1062 0.1062
Brugia malayi Pre-SET motif family protein 0.0042 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0198 0.1286 0.1286
Onchocerca volvulus Cathepsin L homolog 0.0459 0.3103 1
Toxoplasma gondii NADPH-glutathione reductase 0.0022 0.006 0.0084
Mycobacterium tuberculosis Probable hydrolase 0.0094 0.0558 0.1302
Schistosoma mansoni hypothetical protein 0.0648 0.4423 0.4423
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.053 0.3596 1
Trichomonas vaginalis glucosylceramidase, putative 0.0127 0.0787 0.2171
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi glutathione reductase 0.0065 0.0355 0.0355
Schistosoma mansoni neuropeptide receptor 0.0038 0.0166 0.0166
Leishmania major hypothetical protein, conserved 0.0025 0.0079 0.0198
Onchocerca volvulus 0.0094 0.0558 0.1716
Brugia malayi cathepsin F-like cysteine proteinase 0.0138 0.0867 0.0867
Leishmania major beta tubulin 0.0167 0.107 0.296
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Toxoplasma gondii beta tubulin 0.0167 0.107 0.2916
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0459 0.3103 1
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0743 0.0743
Schistosoma mansoni pyruvate kinase 0.0018 0.003 0.003
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Onchocerca volvulus 0.0038 0.0166 0.0442
Trypanosoma brucei epsilon tubulin 0.0088 0.0519 0.1424
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0256 0.1691 0.1684
Loa Loa (eye worm) hypothetical protein 0.0121 0.0746 0.0746
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Mycobacterium ulcerans thymidylate synthase 0.0122 0.0751 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Schistosoma mansoni tubulin subunit beta 0.0038 0.0171 0.0171
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis pyruvate kinase 0.0018 0.003 0.003
Schistosoma mansoni tubulin subunit alpha 0.0121 0.0746 0.0746
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0022 0.006 0.006
Trypanosoma cruzi cysteine peptidase, putative 0.0256 0.1691 0.1684
Brugia malayi neuropeptide F receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0166 0.0166
Brugia malayi Proteasome A-type and B-type family protein 0.0069 0.0384 0.0384
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0082 0.0479 0.0479
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0927
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0426
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0181 0.0372
Onchocerca volvulus 0.0038 0.0166 0.0442
Echinococcus granulosus intermediate filament protein 0.0076 0.0434 0.0434
Plasmodium falciparum tubulin gamma chain 0.0088 0.0519 0.159
Giardia lamblia NADH oxidase lateral transfer candidate 0.0022 0.006 0.0084
Trypanosoma brucei cysteine peptidase, putative 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0627 0.0627
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0.0079 0.0079
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.053 0.3596 0.3596
Schistosoma mansoni aryl hydrocarbon receptor 0.0036 0.0155 0.0155
Brugia malayi hypothetical protein 0.0058 0.0307 0.0307
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0025 0.0079 0.0079
Trypanosoma brucei alpha tubulin 0.0121 0.0746 0.2056
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0025 0.0079 0.0079
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0076 0.0147
Echinococcus granulosus voltage gated hydrogen channel 1 0.0025 0.0079 0.0079
Echinococcus multilocularis calpain 7 (C02 family) 0.0063 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Schistosoma mansoni neuropeptide receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0103 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0171 0.1096 0.3033
Loa Loa (eye worm) acetylcholine receptor protein 0.007 0.0394 0.0394
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0166 0.0166
Echinococcus granulosus neutral alpha glucosidase AB 0.0019 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.053 0.3596 1
Plasmodium vivax tubulin gamma chain, putative 0.0088 0.0519 0.159
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Onchocerca volvulus Peroxidasin homolog 0.0104 0.0627 0.1941
Toxoplasma gondii cathepsin CPL 0.0459 0.3103 0.8619
Echinococcus granulosus pyruvate kinase 0.0018 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin beta chain, putative 0.005 0.0252 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Echinococcus granulosus thymidylate synthase 0.0122 0.0751 0.0751
Giardia lamblia Hypothetical protein 0.0118 0.0728 0.1957
Brugia malayi Cytochrome P450 family protein 0.0082 0.0479 0.0479
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus granulosus tubulin delta chain 0.0038 0.0171 0.0171
Leishmania major gamma-tubulin 0.0088 0.0519 0.1424
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0166 0.0166
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0479 0.0479
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Leishmania major cysteine peptidase A (CPA) 0.0459 0.3103 0.8628
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0728 0.0728
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Conserved protein 0.0094 0.0558 0.1302
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) voltage-gated potassium channel 0.0025 0.0079 0.0079
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0728 0.2326
Trypanosoma cruzi alpha tubulin, putative 0.0121 0.0746 0.0738
Mycobacterium ulcerans proteasome PrcB 0.0069 0.0384 0.491
Plasmodium falciparum alpha tubulin 1 0.0121 0.0746 0.2328
Brugia malayi Cytochrome P450 family protein 0.004 0.0181 0.0181
Leishmania major beta tubulin 0.0167 0.107 0.296
Trichomonas vaginalis tubulin epsilon chain, putative 0.0121 0.0746 0.2056
Schistosoma mansoni calcium-activated potassium channel 0.0146 0.0924 0.0924
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0359 0.0359
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.003 0.0071
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Brugia malayi Bloom's syndrome protein homolog 0.0028 0.0099 0.0099
Onchocerca volvulus 0.0038 0.0166 0.0442
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) ryanodine receptor 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus multilocularis pyruvate kinase 0.0028 0.0098 0.0098
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0025 0.0079 0.0079
Leishmania major beta tubulin 0.0167 0.107 0.296
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.012 0.012
Trypanosoma brucei glucosidase, putative 0.0019 0.0038 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0025 0.0079 0.0079
Echinococcus granulosus thioredoxin glutathione reductase 0.0065 0.0355 0.0355
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi Dopamine receptor protein 1 0.0038 0.0166 0.0166
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0069 0.0384 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0171 0.0453
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Echinococcus multilocularis carboxylesterase 5A 0.0053 0.0274 0.0274
Brugia malayi hypothetical protein 0.0234 0.1538 0.1538
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0166 0.0166
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0166 0.0166
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0058 0.0307 0.0299
Echinococcus granulosus tubulin alpha chain 0.0121 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0082 0.0479 0.0479
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0164 0.1048 0.2513
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Brugia malayi Cathepsin L-like precursor 0.0321 0.214 0.214
Echinococcus multilocularis nAChR subunit 0.0145 0.0914 0.0914
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0145 0.0914 0.0914
Echinococcus granulosus potassium large conductance calcium activated 0.0025 0.0079 0.0079
Plasmodium vivax vivapain-2 0.0459 0.3103 1
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1538 0.1538
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0145 0.0914 0.0914
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Loa Loa (eye worm) cysteine protease 0.0459 0.3103 0.3103
Loa Loa (eye worm) hypothetical protein 0.0234 0.1538 0.1538
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0019 0.0038 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trypanosoma cruzi polo-like protein kinase, putative 0.005 0.0256 0.0248
Entamoeba histolytica cysteine proteinase, putative 0.0256 0.1691 0.5437
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus fmrfamide receptor 0.0038 0.0166 0.0166
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0927
Schistosoma mansoni inositol monophosphatase 0.0037 0.0161 0.0161
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0166 0.0166
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0075
Loa Loa (eye worm) ACC-1 protein 0.0145 0.0914 0.0914
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0252 0.0679
Echinococcus granulosus beta LACTamase domain containing family member 0.0094 0.0558 0.0558
Entamoeba histolytica cysteine protease, putative 0.0459 0.3103 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0239 0.0239
Echinococcus granulosus microtubule associated protein 2 0.0732 0.5005 0.5005
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.015 0.0391
Leishmania major epsilon tubulin, putative 0.0088 0.0519 0.1424
Onchocerca volvulus 0.0459 0.3103 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0053 0.0274 0.0274
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0166 0.0166
Leishmania major zeta tubulin, putative 0.0038 0.0171 0.0453
Mycobacterium leprae Probable lipase LipE 0.0094 0.0558 0.518
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0359 0.0359
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0028 0.0097 0.0928
Echinococcus granulosus hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus single minded 2 0.0029 0.0106 0.0106
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0239 0.0239
Echinococcus granulosus tar DNA binding protein 0.0065 0.0359 0.0359
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0728 0.2271
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0728 0.2007
Echinococcus multilocularis peroxidasin 0.0104 0.0627 0.0627
Mycobacterium leprae putative cytochrome p450 0.004 0.0181 0.1478
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0237 0.0237
Brugia malayi AKH receptor 0.0038 0.0166 0.0166
Onchocerca volvulus 0.007 0.0394 0.1182
Brugia malayi Tubulin gamma chain 0.0088 0.0519 0.0519
Giardia lamblia Epsilon tubulin 0.0038 0.0171 0.0394
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0099 0.0597 0.0597
Brugia malayi Cytochrome P450 family protein 0.012 0.0742 0.0742
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Schistosoma mansoni biogenic amine (5HT) receptor 0.0202 0.1312 0.1312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Onchocerca volvulus 0.0076 0.0434 0.1314
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0166 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0022 0.006 0.0084
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0145 0.0914 0.0914
Echinococcus granulosus glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Echinococcus granulosus bloom syndrome protein 0.0028 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Trypanosoma cruzi trypanothione reductase, putative 0.0022 0.006 0.0052
Onchocerca volvulus 0.005 0.0255 0.073
Trypanosoma brucei calpain, putative 0.0019 0.0035 0.0075
Echinococcus multilocularis musashi 0.0076 0.0434 0.0434
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0426
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0022 0.006 0.0097
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0145 0.0914 0.0914
Loa Loa (eye worm) tubulin beta-2A chain 0.0167 0.107 0.107
Trypanosoma brucei Calpain-like protein 2 0.0019 0.0035 0.0075
Trypanosoma brucei hypothetical protein 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0019 0.0038 0.0084
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0145 0.0914 0.0914
Trypanosoma brucei alpha tubulin, putative 0.005 0.0252 0.0679
Schistosoma mansoni neurotransmitter gated ion channel 0.0075 0.0424 0.0424
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.02 0.02
Echinococcus granulosus pyruvate kinase 0.0035 0.015 0.015
Echinococcus granulosus voltage gated potassium channel 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0321 0.214 0.214
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0029 0.0103 0.0103
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Brugia malayi Tubulin alpha-2 chain 0.0121 0.0746 0.0746
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.015 0.0391
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Onchocerca volvulus 0.0145 0.0914 0.2875
Toxoplasma gondii hypothetical protein 0.0025 0.0079 0.0137
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0118 0.0728 0.2007
Mycobacterium ulcerans putative regulatory protein 0.0027 0.009 0.0824
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0171 0.1096 0.299
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0022 0.006 0.0415
Echinococcus granulosus Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Entamoeba histolytica hypothetical protein 0.0024 0.0069 0.0196
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1448 1 1
Giardia lamblia Beta tubulin 0.0167 0.107 0.2916
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0022 0.006 0.0415
Brugia malayi Carboxylesterase family protein 0.0053 0.0274 0.0274
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0118 0.0728 0.0728
Trypanosoma brucei Calpain-like protein 1.2 0.0019 0.0035 0.0075
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis sodium leak channel non selective protein 0.0025 0.0079 0.0079
Leishmania major cytochrome p450-like protein 0.0082 0.0479 0.1311
Brugia malayi cytoplasmic intermediate filament protein 0.0041 0.0188 0.0188
Brugia malayi Tubulin alpha-2 chain 0.0121 0.0746 0.0746
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Loa Loa (eye worm) calcium channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0025 0.0079 0.0079
Plasmodium vivax proteasome subunit beta type-5, putative 0.0069 0.0384 0.1151
Brugia malayi Intermediate filament tail domain containing protein 0.0076 0.0434 0.0434
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0459 0.3103 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0166 0.0166
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0333
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0479 0.0471
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0599 0.4082 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0728 0.0728
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.006 0.0052
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0118 0.0728 0.0728
Onchocerca volvulus Peroxidase homolog 0.0104 0.0627 0.1941
Brugia malayi bHLH-PAS transcription factor 0.0027 0.009 0.009
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0025 0.0079 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0025 0.0079 0.0079
Echinococcus granulosus tubulin gamma 1 chain 0.0088 0.0519 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Entamoeba histolytica cysteine proteinase, putative 0.0256 0.1691 0.5437
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0166 0.0166
Brugia malayi Dihydrofolate reductase 0.005 0.0249 0.0249
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0166 0.0166
Echinococcus granulosus tubulin alpha chain 0.0121 0.0746 0.0746
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Schistosoma mansoni calcium-activated potassium channel 0.019 0.123 0.123
Echinococcus multilocularis thioredoxin glutathione reductase 0.0065 0.0355 0.0355
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Onchocerca volvulus 0.0459 0.3103 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0087 0.051 0.051
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.005 0.0252 0.0679
Loa Loa (eye worm) hypothetical protein 0.0138 0.0867 0.0867
Echinococcus granulosus peroxisome assembly protein 26 0.0121 0.0746 0.0746
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0.0079 0.0079
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.007 0.0394 0.0394
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0118 0.0728 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0118 0.0728 0.2007
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0341 0.0927
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0341 0.0333
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0145 0.0914 0.0914
Chlamydia trachomatis dihydrofolate reductase 0.005 0.0249 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Toxoplasma gondii beta-1 tubulin, putative 0.0167 0.107 0.2916
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0171 0.0394
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0166 0.0166
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0728 0.072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0166 0.0166
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0103 0.0103
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0.0079 0.0079
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0183 0.1181 0.1181
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0728 0.2007
Brugia malayi calpain 5 0.0044 0.0209 0.0209
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0029 0.0103 0.0103
Schistosoma mansoni myosin xvIII 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Brugia malayi Glycosyl hydrolases family 31 protein 0.0019 0.0038 0.0038
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0148 0.0934 0.223
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0181 0.2089
Echinococcus multilocularis sex peptide receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) beta-tubulin 0.0167 0.107 0.107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0025 0.0079 0.0137
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0094 0.0558 0.1302
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0118 0.0728 0.2271
Trichomonas vaginalis D-aminoacylase, putative 0.0094 0.0558 0.1532
Echinococcus multilocularis tubulin subunit TubB 0.0121 0.0746 0.0746
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Mycobacterium tuberculosis Probable reductase 0.0148 0.0934 0.223
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Echinococcus granulosus cathepsin L 0.0256 0.1691 0.1691
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0025 0.0079 0.0079
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0181 0.2089
Trichomonas vaginalis mercuric reductase, putative 0.0022 0.006 0.0145
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0025 0.0079 0.0079
Echinococcus granulosus cathepsin l1 0.0321 0.214 0.214
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0145 0.0914 0.0914
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0181 0.0372
Brugia malayi RE15519p 0.0038 0.0166 0.0166
Toxoplasma gondii preprocathepsin c precursor, putative 0.0118 0.0728 0.1957
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0479 0.0479
Echinococcus multilocularis cathepsin L cysteine protease 0.0459 0.3103 0.3103
Trichomonas vaginalis tubulin, putative 0.0167 0.107 0.296
Giardia lamblia Cysteine protease 0.0118 0.0728 0.1957
Echinococcus granulosus cathepsin b 0.1448 1 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0174 0.1115 0.1115
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0025 0.0079 0.0079
Echinococcus multilocularis sodium channel protein 0.0364 0.2442 0.2442
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Schistosoma mansoni tubulin subunit gamma 0.0088 0.0519 0.0519
Echinococcus multilocularis shaker cognate 0.0025 0.0079 0.0079
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0148 0.0934 0.223
Loa Loa (eye worm) hypothetical protein 0.0321 0.214 0.214
Leishmania major hypothetical protein, conserved 0.0094 0.0558 0.1532
Schistosoma mansoni amine GPCR 0.0038 0.0166 0.0166
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Echinococcus granulosus cathepsin b 0.1448 1 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0145 0.0914 0.0914
Plasmodium vivax unspecified product 0.0118 0.0728 0.2271
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0118 0.0728 0.1957
Loa Loa (eye worm) hypothetical protein 0.0166 0.1062 0.1062
Giardia lamblia Gamma tubulin 0.0088 0.0519 0.1371
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi calpain 7 0.0063 0.0341 0.0341
Echinococcus granulosus cathepsin L 0.0118 0.0728 0.0728
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0058 0.031 0.0911
Echinococcus granulosus glycine receptor subunit beta 0.0145 0.0914 0.0914
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0171 0.1096 0.3469
Leishmania major beta tubulin 0.0167 0.107 0.296
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0181 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Brugia malayi RNA binding protein 0.0065 0.0359 0.0359
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0627 0.0627
Echinococcus granulosus glycine receptor subunit alpha 1 0.0145 0.0914 0.0914
Loa Loa (eye worm) calpain family protein 1 0.0122 0.0757 0.0757
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.015 0.0396
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0627 0.0627
Trypanosoma brucei beta tubulin 0.0167 0.107 0.296
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0076 0.0434 0.0434
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0025 0.0079 0.0079
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0047 0.0231 0.0231
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0069 0.0384 0.0384
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0459 0.3103 0.3103
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0181 0.0372
Brugia malayi acetyltransferase, GNAT family protein 0.0198 0.1286 0.1286
Brugia malayi Cathepsin L-like precursor 0.0138 0.0867 0.0867
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0459 0.3103 0.3103
Echinococcus granulosus tubulin beta 4A class IVa 0.0167 0.107 0.107
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0359 0.0359
Trichomonas vaginalis D-aminoacylase, putative 0.0094 0.0558 0.1532
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0181 0.2089
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0038 0.0084
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Brugia malayi follicle stimulating hormone receptor 0.0535 0.3633 0.3633
Trypanosoma brucei pyruvate kinase 1 0.0035 0.015 0.0396
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.007 0.0394 0.0394
Echinococcus granulosus beta tubulin 0.0167 0.107 0.107
Echinococcus granulosus lamin 0.0076 0.0434 0.0434
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0246 0.0606
Plasmodium vivax tubulin beta chain, putative 0.0167 0.107 0.3384
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0025 0.0079 0.0079
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Loa Loa (eye worm) dihydrofolate reductase 0.005 0.0249 0.0249
Brugia malayi serine/threonine-protein kinase plk-2 0.005 0.0256 0.0256
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0037 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0028 0.0097 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0069 0.0386 0.0386
Plasmodium falciparum serine repeat antigen 4 0.0118 0.0728 0.2271
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0022 0.006 0.006
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0181 0.1478
Leishmania major beta tubulin 0.0167 0.107 0.296
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0166 0.0166
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Echinococcus multilocularis cathepsin L 0.0118 0.0728 0.0728
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0166 0.0442
Plasmodium vivax tubulin alpha chain, putative 0.0121 0.0746 0.2328
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0022 0.006 0.006
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0181 0.2089
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.015 0.0396
Brugia malayi calpain 5 0.0019 0.0035 0.0035
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.005 0.025 0.025
Schistosoma mansoni cathepsin s 0.0138 0.0867 0.0867
Echinococcus granulosus serine:threonine protein kinase PLK1 0.005 0.0256 0.0256
Onchocerca volvulus 0.0025 0.0079 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0333
Loa Loa (eye worm) tubulin alpha 2 0.0033 0.0131 0.0131
Echinococcus multilocularis tubulin alpha 0.0088 0.0519 0.0519
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0728 0.2007
Toxoplasma gondii hypothetical protein 0.0025 0.0079 0.0137
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0161 0.0366
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0181 0.0372
Trypanosoma brucei zeta tubulin, putative 0.0038 0.0171 0.0453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0019 0.0038 0.0084
Toxoplasma gondii cathepsin B 0.053 0.3596 1
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.005 0.0249 0.3038
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0728 0.072
Echinococcus granulosus GA binding protein alpha chain 0.0047 0.0231 0.0231
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0145 0.0914 0.0914
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0028 0.0097 0.0248
Mycobacterium tuberculosis Conserved protein 0.0094 0.0558 0.1302
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0042 0.02 0.02
Trichomonas vaginalis DNA helicase recq1, putative 0.0028 0.0099 0.0254
Echinococcus multilocularis short transient receptor potential channel 6 0.0025 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Echinococcus multilocularis tubulin alpha chain 0.0121 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0166 0.0166
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0166 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0097 0.0217
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Echinococcus granulosus tubulin subunit beta 0.0167 0.107 0.107
Echinococcus granulosus allatostatin A receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis tubulin gamma chain, putative 0.0167 0.107 0.296
Trypanosoma cruzi conserved protein 0.0019 0.0035 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.006 0.0145
Schistosoma mansoni neurotransmitter gated ion channel 0.007 0.0394 0.0394
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0025 0.0079 0.0079
Brugia malayi Cyclic-nucleotide gated cation channel 0.0029 0.0103 0.0103
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0122 0.0751 0.0751
Schistosoma mansoni alpha glucosidase 0.0019 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0104 0.0625 0.0625
Schistosoma mansoni two-pore calcium channel 0.0025 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) fibroinase 0.0459 0.3103 0.3103
Trichomonas vaginalis D-aminoacylase, putative 0.0094 0.0558 0.1532
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0103 0.0103
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0166 0.0166
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Schistosoma mansoni calcium-activated potassium channel 0.0025 0.0079 0.0079
Giardia lamblia Delta tubulin 0.0038 0.0171 0.0394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0079 0.0079
Echinococcus granulosus Tubulin alpha 1 chain 0.0121 0.0746 0.0746
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0103 0.0103
Onchocerca volvulus 0.0038 0.0166 0.0442
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0031 0.012 0.012
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0166 0.0166
Trichomonas vaginalis calpain, putative 0.0019 0.0035 0.0075
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0166 0.0166
Loa Loa (eye worm) calpain 0.0063 0.0341 0.0341
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0166 0.0166
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0728 0.1957
Brugia malayi voltage-dependent calcium channel 0.0025 0.0079 0.0079
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0029 0.0103 0.0103
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0181 0.0372
Loa Loa (eye worm) hypothetical protein 0.0122 0.0751 0.0751
Trichomonas vaginalis tubulin, putative 0.005 0.0252 0.0679
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi larval opioid receptor 0.0038 0.0166 0.0166
Schistosoma mansoni alpha tubulin 0.0121 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0038 0.0084
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0246 0.0703
Echinococcus multilocularis tubulin subunit beta 0.0167 0.107 0.107
Trichomonas vaginalis DNA helicase recq, putative 0.0028 0.0099 0.0254
Brugia malayi cytochrome P450 0.004 0.0181 0.0181
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0038 0.0171 0.0453
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0728 0.0728
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0118 0.0728 0.2271
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0145 0.0914 0.0914
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0041 0.0188 0.0188
Echinococcus granulosus tubulin beta 1 chain 0.0167 0.107 0.107
Brugia malayi Thioredoxin reductase 0.0065 0.0355 0.0355
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0728 0.0728
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Mycobacterium tuberculosis Probable esterase LipL 0.0094 0.0558 0.1302
Schistosoma mansoni ap endonuclease 0.0028 0.0097 0.0097
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0166 0.0166
Brugia malayi Serotonin receptor 0.0038 0.0166 0.0166
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.003 0.0071
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0025 0.0079 0.0159
Trypanosoma brucei beta tubulin 0.0167 0.107 0.296
Onchocerca volvulus 0.0038 0.0166 0.0442
Schistosoma mansoni hypothetical protein 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0148 0.0934 0.223
Brugia malayi cathepsin L precursor 0.0118 0.0728 0.0728
Leishmania major beta tubulin 0.0167 0.107 0.296
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0181 0.0481
Echinococcus granulosus neuropeptide receptor 0.0038 0.0166 0.0166
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.005 0.0256 0.0689
Loa Loa (eye worm) blistered cuticle protein 3 0.0104 0.0627 0.0627
Brugia malayi Peroxidasin 0.0104 0.0627 0.0627
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.005 0.0249 0.054
Schistosoma mansoni peroxidasin 0.0104 0.0627 0.0627
Trypanosoma cruzi hypothetical protein, conserved 0.0094 0.0558 0.055
Echinococcus multilocularis Tubulin beta 2C chain 0.0167 0.107 0.107
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0239 0.0239
Schistosoma mansoni cathepsin C 0.0118 0.0728 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0181 0.2089
Brugia malayi Serotonin receptor 0.0038 0.0166 0.0166
Mycobacterium tuberculosis Cell division protein FtsZ 0.0038 0.0171 0.0347
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0256 0.1691 0.4691
Brugia malayi Tubulin beta chain 0.0038 0.0171 0.0171
Schistosoma mansoni tubulin subunit epsilon 0.0088 0.0519 0.0519
Onchocerca volvulus 0.0038 0.0166 0.0442
Trypanosoma cruzi trypanothione reductase, putative 0.0065 0.0355 0.0347
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0025 0.0079 0.0137
Brugia malayi Papain family cysteine protease containing protein 0.0256 0.1691 0.1691
Loa Loa (eye worm) voltage-dependent calcium channel 0.0025 0.0079 0.0079
Echinococcus multilocularis glycine receptor subunit beta 0.0145 0.0914 0.0914
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0145 0.0914 0.0914
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0166 0.0166
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0145 0.0914 0.0914
Brugia malayi hypothetical protein 0.0024 0.0069 0.0069
Plasmodium falciparum serine repeat antigen 6 0.0118 0.0728 0.2271
Trypanosoma brucei Calpain-like protein CALP1.3 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0049 0.0246 0.0246
Onchocerca volvulus 0.0145 0.0914 0.2875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0239 0.0239
Giardia lamblia Cathepsin B precursor 0.0118 0.0728 0.1957
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0148 0.0934 0.8871
Schistosoma mansoni hypothetical protein 0.0038 0.0166 0.0166
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Loa Loa (eye worm) hypothetical protein 0.0506 0.3429 0.3429
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0181 0.2089
Trypanosoma brucei tubulin gamma chain 0.0088 0.0519 0.1424
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0728 0.2271
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0104 0.0625 0.1936
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0166 0.0166
Entamoeba histolytica serine/threonine protein kinase, putative 0.005 0.0256 0.0799
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0.0079 0.0079
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0.0079 0.0079
Loa Loa (eye worm) RecQ helicase 0.0028 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0043 0.0202 0.0202
Brugia malayi hypothetical protein 0.0032 0.0125 0.0125
Mycobacterium leprae conserved hypothetical protein 0.0094 0.0558 0.518
Schistosoma mansoni amine GPCR 0.0038 0.0166 0.0166
Onchocerca volvulus Serine\/threonine kinase homolog 0.005 0.0256 0.0733
Leishmania major beta tubulin 0.0167 0.107 0.296
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0145
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0145 0.0914 0.0914
Brugia malayi Transient-receptor-potential like protein 0.0025 0.0079 0.0079
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0229 0.1499 0.1499
Plasmodium falciparum tubulin epsilon chain, putative 0.0088 0.0519 0.159
Onchocerca volvulus Peroxidase homolog 0.0104 0.0627 0.1941
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0743 0.0743
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0025 0.0079 0.0079
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0252 0.0679
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0088 0.0519 0.1371
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0181 0.0372
Loa Loa (eye worm) ctsf protein 0.0459 0.3103 0.3103
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Schistosoma mansoni calpain-7 (C02 family) 0.0065 0.0354 0.0354
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0103 0.0103
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0022 0.006 0.0145
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Loa Loa (eye worm) GABA receptor subunit 0.0075 0.0424 0.0424
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0627 0.0627
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Echinococcus granulosus shaker cognate 0.0025 0.0079 0.0079
Leishmania major beta tubulin 0.0167 0.107 0.296
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0058 0.031 0.0785
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Echinococcus multilocularis beta LACTamase domain containing family member 0.0094 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Giardia lamblia Beta tubulin 0.0167 0.107 0.2916
Plasmodium vivax calpain, putative 0.0063 0.0341 0.101
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.012 0.012
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0167 0.107 0.107
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0035
Plasmodium falciparum calpain 0.0019 0.0035 0.0016
Echinococcus multilocularis thymidylate synthase 0.0122 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0024 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0239 0.0239
Loa Loa (eye worm) calpain 5 0.0044 0.0209 0.0209
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0166 0.0166
Loa Loa (eye worm) calpain family protein 1 0.0166 0.1062 0.1062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0181 0.0372
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0094 0.0558 0.0558
Mycobacterium ulcerans pyruvate kinase 0.0035 0.015 0.1666
Loa Loa (eye worm) alpha-tubulin 0.0121 0.0746 0.0746
Brugia malayi hypothetical protein 0.007 0.0394 0.0394
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Brugia malayi Cathepsin L-like precursor 0.0321 0.214 0.214
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.015 0.0396
Loa Loa (eye worm) tubulin alpha chain 0.0121 0.0746 0.0746
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0145 0.0914 0.0914
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0025 0.0079 0.0159
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0145 0.0914 0.0914
Onchocerca volvulus Dual oxidase homolog 0.0104 0.0627 0.1941
Onchocerca volvulus 0.0118 0.0728 0.2271
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0118 0.0728 0.2271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Loa Loa (eye worm) inositol-1 0.0037 0.0161 0.0161
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0728 0.0728
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0028 0.0097 0.0287
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Loa Loa (eye worm) pyruvate kinase 0.0035 0.015 0.015
Brugia malayi MH2 domain containing protein 0.012 0.0743 0.0743
Loa Loa (eye worm) acetylcholinesterase 1 0.0053 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Loa Loa (eye worm) intermediate filament protein 0.0076 0.0434 0.0434
Entamoeba histolytica cysteine protease, putative 0.0118 0.0728 0.2326
Mycobacterium tuberculosis Probable lipase LipE 0.0094 0.0558 0.1302
Schistosoma mansoni transient receptor potential channel 4 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0826 0.5664 0.5664
Schistosoma mansoni hypothetical protein 0.0048 0.0237 0.0237
Toxoplasma gondii beta-tubulin, putative 0.0167 0.107 0.2916
Echinococcus granulosus histone acetyltransferase KAT2B 0.0193 0.1247 0.1247
Echinococcus granulosus voltage dependent calcium channel 0.0025 0.0079 0.0079
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0065 0.0355 0.0802
Mycobacterium tuberculosis Probable oxidoreductase 0.0164 0.1048 0.2513
Trypanosoma brucei cysteine peptidase C (CPC) 0.053 0.3596 1
Brugia malayi Tubulin alpha chain 0.0038 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.02 0.02
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0087 0.051 0.051
Schistosoma mansoni dopamine-beta-monooxygenase 0.0122 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.0171 0.0453
Echinococcus granulosus tubulin alpha 0.0088 0.0519 0.0519
Echinococcus granulosus beta tubulin 0.0167 0.107 0.107
Leishmania major cytochrome p450-like protein 0.004 0.0181 0.0481
Schistosoma mansoni neuropeptide receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) pyruvate kinase 0.0035 0.015 0.015
Mycobacterium tuberculosis Probable lipase LipD 0.0094 0.0558 0.1302
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0256 0.1691 0.1691
Trypanosoma cruzi hypothetical protein, conserved 0.0094 0.0558 0.055
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0181 0.0372
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0364 0.2442 0.6784
Echinococcus granulosus Tubulin beta 2C chain 0.0167 0.107 0.107
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0058 0.031 0.0842
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Plasmodium falciparum serine repeat antigen 1 0.0118 0.0728 0.2271
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0038 0.0166 0.0442
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0728 0.2326
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0181 0.2089
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0181 0.2089
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0118 0.0728 0.2271
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0166 0.0442
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0181 0.0173
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0029 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0166 0.0166
Toxoplasma gondii transporter, cation channel family protein 0.0025 0.0079 0.0137
Schistosoma mansoni acetylcholine receptor-related 0.007 0.0394 0.0394
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.015 0.0142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0239 0.0239
Onchocerca volvulus 0.0145 0.0914 0.2875
Echinococcus multilocularis hypothetical protein 0.0121 0.0746 0.0746
Loa Loa (eye worm) tubulin alpha-2 chain 0.0121 0.0746 0.0746
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0166 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.007 0.0394 0.0394
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0166 0.0166
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.005 0.025 0.025
Echinococcus multilocularis two pore calcium channel protein 2 0.0025 0.0079 0.0079
Schistosoma mansoni amine GPCR 0.0038 0.0166 0.0166
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0166 0.0166
Echinococcus multilocularis GA binding protein alpha chain 0.0047 0.0231 0.0231
Echinococcus granulosus voltage gated potassium channel 0.0025 0.0079 0.0079
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Trypanosoma brucei kinesin, putative 0.0044 0.0209 0.0561
Loa Loa (eye worm) hypothetical protein 0.0321 0.214 0.214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0256 0.1691 0.4691
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0181 0.2089
Brugia malayi Dopamine receptor 0.0038 0.0166 0.0166
Echinococcus granulosus short transient receptor potential channel 6 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Onchocerca volvulus 0.0038 0.0166 0.0442
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Echinococcus granulosus g protein coupled receptor 0.0038 0.0166 0.0166
Echinococcus granulosus cathepsin l1 0.0459 0.3103 0.3103
Loa Loa (eye worm) hypoxia-induced factor 1 0.0112 0.0681 0.0681
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0063 0.0341 0.0333
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0069 0.0384 0.0873
Plasmodium falciparum tubulin delta chain, putative 0.0038 0.0171 0.0457
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Brugia malayi beta-lactamase 0.0094 0.0558 0.0558
Echinococcus multilocularis pyruvate kinase 0.0035 0.015 0.015
Echinococcus multilocularis ryanodine receptor 44f 0.0025 0.0079 0.0079
Onchocerca volvulus 0.0038 0.0166 0.0442
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0333
Echinococcus multilocularis peroxisome assembly protein 26 0.0121 0.0746 0.0746
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0246 0.0238
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0145 0.0914 0.0914
Treponema pallidum exodeoxyribonuclease (exoA) 0.0028 0.0097 0.3339
Giardia lamblia Beta tubulin 0.0167 0.107 0.2916
Onchocerca volvulus 0.0459 0.3103 1
Plasmodium falciparum serine repeat antigen 9 0.0118 0.0728 0.2271
Entamoeba histolytica hypothetical protein 0.0024 0.0069 0.0196
Giardia lamblia Pyruvate kinase 0.0035 0.015 0.0337
Echinococcus multilocularis somatostatin receptor 0.0038 0.0166 0.0166
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0171 0.1096 0.3469
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0103 0.0103
Echinococcus granulosus sex peptide receptor 0.0038 0.0166 0.0166
Entamoeba histolytica cysteine proteinase, putative 0.0459 0.3103 1
Schistosoma mansoni hypothetical protein 0.0022 0.0057 0.0057
Trypanosoma brucei alpha tubulin 0.0121 0.0746 0.2056
Brugia malayi Cathepsin L-like precursor 0.0459 0.3103 0.3103
Echinococcus granulosus tubulin alpha 3 chain 0.0121 0.0746 0.0746
Brugia malayi hypothetical protein 0.0104 0.0627 0.0627
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0035 0.015 0.015
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0394 0.0394
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0519 0.1424
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0038 0.0084
Echinococcus granulosus tubulin alpha 3 chain 0.0121 0.0746 0.0746
Brugia malayi hypothetical protein 0.007 0.0394 0.0394
Trichomonas vaginalis tubulin epsilon chain, putative 0.0121 0.0746 0.2056
Echinococcus granulosus histone lysine methyltransferase setb 0.0042 0.02 0.02
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0019 0.0035 0.0027
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0035 0.0027
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0459 0.3103 0.3103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0266 0.0266
Plasmodium falciparum alpha tubulin 2 0.0121 0.0746 0.2328
Trichomonas vaginalis bromodomain-containing protein, putative 0.0058 0.031 0.0842
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0118 0.0728 0.2271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0166 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) glutathione reductase 0.0065 0.0355 0.0355
Echinococcus granulosus cysteine protease 0.0256 0.1691 0.1691
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0166 0.0166
Loa Loa (eye worm) tubulin gamma chain 0.0088 0.0519 0.0519
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0022 0.006 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Echinococcus multilocularis beta tubulin 0.0167 0.107 0.107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0048 0.0237 0.0673
Echinococcus multilocularis cathepsin b 0.1448 1 1
Schistosoma mansoni alpha tubulin 0.0121 0.0746 0.0746
Loa Loa (eye worm) alpha-tubulin 0.0121 0.0746 0.0746
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0145 0.0914 0.0914
Plasmodium falciparum tubulin beta chain 0.0167 0.107 0.3384
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0075 0.0424 0.0424
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0075 0.0424 0.0424
Schistosoma mansoni cathepsin B (C01 family) 0.0118 0.0728 0.0728
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0246 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0038 0.003
Mycobacterium tuberculosis Conserved protein 0.0094 0.0558 0.1302
Giardia lamblia Alpha-tubulin 0.0121 0.0746 0.2007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0094 0.0558 0.1302
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Trypanosoma cruzi cysteine peptidase, putative 0.0459 0.3103 0.3098
Echinococcus granulosus orexin receptor type 2 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0321 0.214 0.6866
Echinococcus granulosus pyruvate kinase 0.0035 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0025 0.0079 0.0079
Loa Loa (eye worm) acetyltransferase 0.0198 0.1286 0.1286
Plasmodium vivax thioredoxin reductase, putative 0.0065 0.0355 0.1057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0728 0.2007
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0.0079 0.0079
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0019 0.0035 0.0014
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Toxoplasma gondii transporter, cation channel family protein 0.0025 0.0079 0.0137
Trypanosoma brucei alpha tubulin 0.0121 0.0746 0.2056
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0181 0.2089
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0164 0.1048 0.2513
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0728 0.0728
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Onchocerca volvulus 0.0042 0.02 0.0551
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.006 0.0145
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0384 0.1048
Echinococcus granulosus geminin 0.0648 0.4423 0.4423
Echinococcus multilocularis transient receptor potential gamma protein 0.0025 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0166 0.0166
Echinococcus granulosus pyruvate kinase 0.0018 0.003 0.003
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0183 0.1181 0.1181
Mycobacterium ulcerans lipase LipD 0.0094 0.0558 0.732
Brugia malayi Inositol-1 0.0037 0.0161 0.0161
Schistosoma mansoni cathepsin F (C01 family) 0.0321 0.214 0.214
Onchocerca volvulus 0.0099 0.0597 0.1844
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0166 0.0166
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0166 0.0166
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0104 0.0627 0.1941
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0025 0.0079 0.0198
Echinococcus multilocularis tubulin alpha chain 0.0121 0.0746 0.0746
Schistosoma mansoni cathepsin F (C01 family) 0.0459 0.3103 0.3103
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Onchocerca volvulus 0.0038 0.0166 0.0442
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0728 0.0728
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0161 0.0426
Entamoeba histolytica acetyltransferase, GNAT family 0.0053 0.0276 0.0866
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1181 0.327
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0181 0.0372
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Schistosoma mansoni cathepsin F (C01 family) 0.0459 0.3103 0.3103
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0166 0.0166
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0082 0.0479 0.6221
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0256 0.0689
Loa Loa (eye worm) thymidylate synthase 0.0122 0.0751 0.0751
Loa Loa (eye worm) ACC-1 protein 0.0145 0.0914 0.0914
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0075 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Schistosoma mansoni adenoreceptor 0.0038 0.0166 0.0166
Trypanosoma brucei epsilon tubulin 0.0088 0.0519 0.1424
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0028 0.0097 0.0165
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0246 0.0703
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Mycobacterium leprae cell division protein FtsZ 0.0038 0.0171 0.1381
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0198 0.1286 0.1286
Trichomonas vaginalis calpain, putative 0.0019 0.0035 0.0075
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Schistosoma mansoni microtubule-associated protein tau 0.0732 0.5005 0.5005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Treponema pallidum cell division protein FtsZ 0.0038 0.0171 1
Schistosoma mansoni vesicular amine transporter 0.0025 0.0079 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0166 0.0166
Schistosoma mansoni tubulin subunit alpha 0.0121 0.0746 0.0746
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0028 0.0097 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Echinococcus granulosus hypothetical protein 0.0025 0.0079 0.0079
Schistosoma mansoni gabp alpha 0.0047 0.0231 0.0231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0052
Leishmania major beta tubulin 0.0167 0.107 0.296
Echinococcus granulosus voltage dependent calcium channel 0.0025 0.0079 0.0079
Brugia malayi AMP-binding enzyme family protein 0.0018 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0867 0.0859
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.003
Entamoeba histolytica tubulin alpha-1 chain 0.0121 0.0746 0.2383
Onchocerca volvulus 0.0094 0.0558 0.1716
Loa Loa (eye worm) hypothetical protein 0.0076 0.0434 0.0434
Echinococcus granulosus potassium voltage gated channel subfamily H 0.005 0.025 0.025
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0025 0.0079 0.0079
Brugia malayi Cell division protein ftsZ 0.0038 0.0171 0.0171
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0166 0.0166
Schistosoma mansoni hypothetical protein 0.0648 0.4423 0.4423
Loa Loa (eye worm) beta-lactamase 0.0094 0.0558 0.0558
Echinococcus granulosus glycine receptor subunit beta 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0435 0.2939 0.2939
Brugia malayi Blistered cuticle protein 3 0.0104 0.0627 0.0627
Schistosoma mansoni lamin 0.0076 0.0434 0.0434
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0181 0.2089
Loa Loa (eye worm) hypothetical protein 0.0104 0.0627 0.0627
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0046 0.0226 0.0226
Echinococcus multilocularis tubulin alpha 3 chain 0.0121 0.0746 0.0746
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1448 1 1
Plasmodium falciparum serine repeat antigen 3 0.0118 0.0728 0.2271
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0166 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0145 0.0914 0.0914
Schistosoma mansoni neuropeptide receptor 0.0038 0.0166 0.0166
Schistosoma mansoni transient receptor potential channel 0.0025 0.0079 0.0079
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0575 0.3915 0.3915
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0103 0.0103
Schistosoma mansoni peptidylglycine monooxygenase 0.0122 0.0751 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0728 0.2007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0459 0.3103 0.8628
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0166 0.0166
Plasmodium falciparum pyruvate kinase 0.0035 0.015 0.0391
Entamoeba histolytica cysteine proteinase, putative 0.0256 0.1691 0.5437
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0459 0.3103 0.3103
Leishmania major hypothetical protein, unknown function 0.0019 0.0035 0.0075
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0029 0.0103 0.0103
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0181 0.0481
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0166 0.0166
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0181 0.2089
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Trypanosoma cruzi kinesin, putative 0.0044 0.0209 0.0201
Schistosoma mansoni ap endonuclease 0.0028 0.0097 0.0097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0035 0.0027
Echinococcus granulosus biogenic amine 5HT receptor 0.0202 0.1312 0.1312
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Brugia malayi hypothetical protein 0.0038 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.3103 0.8628
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Trypanosoma brucei epsilon tubulin 0.0088 0.0519 0.1424
Echinococcus granulosus two pore calcium channel protein 2 0.0025 0.0079 0.0079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0034 0.0011
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Giardia lamblia Hypothetical protein 0.0118 0.0728 0.1957
Loa Loa (eye worm) hypothetical protein 0.0037 0.016 0.016
Echinococcus multilocularis Tubulin beta 2C chain 0.0167 0.107 0.107
Loa Loa (eye worm) hypothetical protein 0.0094 0.0558 0.0558
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0171 0.0394
Onchocerca volvulus 0.005 0.0252 0.0721
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0867 0.0859
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0181 0.0372
Echinococcus multilocularis transfer RNA-Gly 0.0025 0.0079 0.0079
Plasmodium vivax unspecified product 0.0256 0.1691 0.5404
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Trypanosoma cruzi cysteine peptidase, putative 0.0459 0.3103 0.3098
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0166 0.1062 0.1062
Schistosoma mansoni lamin 0.0076 0.0434 0.0434
Trichomonas vaginalis tubulin, putative 0.0038 0.0171 0.0453
Echinococcus multilocularis Tubulin beta 2C chain 0.0167 0.107 0.107
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0728 0.1957
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0118 0.0728 0.0728
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0459 0.3103 0.8628
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0479 0.0471
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0333
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0025 0.0079 0.0079
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0025 0.0079 0.0079
Brugia malayi Ets-domain containing protein 0.0047 0.0231 0.0231
Leishmania major hypothetical protein, unknown function 0.0025 0.0079 0.0198
Loa Loa (eye worm) hypothetical protein 0.0229 0.1499 0.1499
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0171 0.0163
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.04 0.2695 0.867
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Loa Loa (eye worm) animal heme peroxidase 0.0104 0.0627 0.0627
Brugia malayi hypothetical protein 0.007 0.0394 0.0394
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0025 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.007 0.0394 0.0394
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0103 0.0103
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0103 0.0103
Onchocerca volvulus Cathepsin L homolog 0.0459 0.3103 1
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0079 0.0079
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0229 0.1499 0.1499
Trypanosoma brucei Calpain-like protein 1.1 0.0019 0.0035 0.0075
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0069 0.0384 0.1214
Toxoplasma gondii transporter, cation channel family protein 0.0025 0.0079 0.0137
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.007 0.0394 0.0394
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0022 0.006 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0035 0.0075
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.007 0.0394 0.0394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.006
Trichomonas vaginalis sucrase-isomaltase, putative 0.0019 0.0038 0.0084
Loa Loa (eye worm) cathepsin B 0.053 0.3596 0.3596
Leishmania major alpha glucosidase II subunit, putative 0.0019 0.0038 0.0084
Echinococcus multilocularis acetylcholinesterase 0.0053 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0145 0.0914 0.0914
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0627 0.0627
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0166 0.0166
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0042 0.02 0.0474
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0166 0.0166
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0341 0.0333
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0025 0.0079 0.0079
Schistosoma mansoni ets-related 0.0142 0.0897 0.0897
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0181 0.0422
Brugia malayi Dopamine receptor protein 2 0.0038 0.0166 0.0166
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0166 0.0166
Schistosoma mansoni voltage-gated cation channel 0.0025 0.0079 0.0079
Trichomonas vaginalis tubulin epsilon chain, putative 0.0167 0.107 0.296
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.007 0.0394 0.0394
Loa Loa (eye worm) hypothetical protein 0.0075 0.0424 0.0424
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.019 0.123 0.123
Onchocerca volvulus 0.0459 0.3103 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0166 0.0166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0256 0.1691 0.4691
Brugia malayi Animal haem peroxidase family protein 0.0104 0.0627 0.0627
Echinococcus granulosus calpain 7 C02 family 0.0063 0.0341 0.0341
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0145 0.0914 0.0914
Brugia malayi G-protein coupled receptor 0.0038 0.0166 0.0166
Echinococcus granulosus carboxylesterase 5A 0.0053 0.0274 0.0274
Brugia malayi Cation transporter family protein 0.0145 0.0914 0.0914
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0145 0.0914 0.0914
Echinococcus granulosus tubulin alpha chain 0.0121 0.0746 0.0746
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0153
Echinococcus granulosus acetylcholinesterase 0.0053 0.0274 0.0274
Leishmania major delta tubulin, putative 0.0038 0.0171 0.0453
Trichomonas vaginalis penicillin-binding protein, putative 0.0094 0.0558 0.1532
Schistosoma mansoni 60S ribosomal protein L21 0.0028 0.0096 0.0096
Giardia lamblia Cathepsin L precursor 0.0118 0.0728 0.1957
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.005 0.025 0.025
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0166 0.0166
Giardia lamblia Cysteine protease 0.0118 0.0728 0.1957
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1448 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.006 0.0145
Plasmodium vivax hypothetical protein, conserved 0.0094 0.0558 0.1716
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Trypanosoma brucei zeta tubulin 0.0038 0.0171 0.0453
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0019 0.0035 0.0075
Brugia malayi ORL1-like opioid receptor 0.0038 0.0166 0.0166
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0022 0.006 0.0145
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0166 0.0166
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0161 0.0426
Echinococcus granulosus transient receptor potential gamma protein 0.0025 0.0079 0.0079
Brugia malayi beta-lactamase family protein 0.0094 0.0558 0.0558
Brugia malayi exodeoxyribonuclease III family protein 0.0028 0.0097 0.0097
Trichomonas vaginalis tubulin beta chain, putative 0.0121 0.0746 0.2056
Brugia malayi calpain family protein 1 0.0166 0.1062 0.1062
Schistosoma mansoni cytochrome P450 0.004 0.0181 0.0181
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.005 0.0256 0.0256
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0166 0.0166
Loa Loa (eye worm) LGC-31 protein 0.0145 0.0914 0.0914
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0075 0.0424 0.0424
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0728 0.1957
Brugia malayi dihydrofolate reductase family protein 0.005 0.0249 0.0249
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0166 0.0166
Schistosoma mansoni acetylcholine receptor subunit beta 0.007 0.0394 0.0394
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.007 0.0394 0.0394
Trichomonas vaginalis glutathione reductase, putative 0.0022 0.006 0.0145
Loa Loa (eye worm) hypothetical protein 0.0038 0.0166 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0075
Onchocerca volvulus 0.0038 0.0166 0.0442
Trypanosoma cruzi tubulin delta chain 0.0038 0.0171 0.0163
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0166 0.0166
Onchocerca volvulus 0.0038 0.0166 0.0442
Schistosoma mansoni calpain-2 (C02 family) 0.0019 0.0035 0.0035
Plasmodium falciparum serine repeat antigen 8 0.0118 0.0728 0.2271
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0118 0.0728 0.2007
Loa Loa (eye worm) tubulin beta-4 chain 0.0167 0.107 0.107
Loa Loa (eye worm) hypothetical protein 0.0053 0.0274 0.0274
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0519 0.0511
Schistosoma mansoni tubulin subunit beta 0.0167 0.107 0.107
Onchocerca volvulus 0.0027 0.009 0.0193
Leishmania major alpha tubulin 0.0121 0.0746 0.2056
Echinococcus granulosus ryanodine receptor 44f 0.0025 0.0079 0.0079
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0166 0.0166
Loa Loa (eye worm) BEN-1 protein 0.0167 0.107 0.107
Brugia malayi intermediate filament protein 0.0076 0.0434 0.0434
Echinococcus multilocularis tubulin alpha chain 0.0121 0.0746 0.0746
Brugia malayi beta-lactamase family protein 0.0094 0.0558 0.0558
Onchocerca volvulus 0.0145 0.0914 0.2875
Mycobacterium ulcerans cell division protein FtsZ 0.0038 0.0171 0.1951
Loa Loa (eye worm) fli-1 protein 0.0142 0.0897 0.0897
Toxoplasma gondii alpha tubulin TUBA1 0.0121 0.0746 0.2007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0025 0.0079 0.0079
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0.0079 0.0079
Echinococcus granulosus TRP transient receptor potential channel 0.0025 0.0079 0.0079
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0742 0.2045
Echinococcus granulosus lysosomal alpha glucosidase 0.0087 0.051 0.051
Echinococcus multilocularis cysteine protease 0.0459 0.3103 0.3103
Toxoplasma gondii ABC1 family protein 0.0094 0.0558 0.1479
Plasmodium falciparum thioredoxin reductase 0.0065 0.0355 0.1057
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0341 0.0927
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0181 0.2089
Leishmania major calpain protease-like protein 0.0019 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0145 0.0914 0.0914
Brugia malayi putative neuropeptide receptor 0.0038 0.0166 0.0166
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.003 0.0062
Echinococcus granulosus Tubulin beta 2C chain 0.0167 0.107 0.107
Echinococcus multilocularis pyruvate kinase 0.0035 0.015 0.015
Trypanosoma brucei antigen, putative 0.0063 0.0341 0.0927
Loa Loa (eye worm) hypothetical protein 0.0025 0.0076 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.02 0.02
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0166 0.0166
Brugia malayi tubulin alpha-2 chain 0.0121 0.0746 0.0746
Entamoeba histolytica cysteine protease, putative 0.0256 0.1691 0.5437
Giardia lamblia Cathepsin L-like protease 0.0118 0.0728 0.1957
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0094 0.0558 0.0558
Toxoplasma gondii proteasome subunit beta type, putative 0.0069 0.0384 0.0992
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0025 0.0079 0.0079
Brugia malayi Pre-SET motif family protein 0.0296 0.1966 0.1966
Brugia malayi PAS domain containing protein 0.0036 0.0155 0.0155
Trypanosoma cruzi polo-like protein kinase, putative 0.005 0.0256 0.0248
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0022 0.006 0.0145
Brugia malayi hypothetical protein 0.0049 0.0246 0.0246
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0181 0.2089
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.006 0.0321 0.0321
Echinococcus multilocularis acetylcholinesterase 0.0053 0.0274 0.0274
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0166 0.0166
Brugia malayi cathepsin L-like cysteine proteinase 0.0118 0.0728 0.0728
Trichomonas vaginalis alpha-glucosidase, putative 0.0019 0.0038 0.0084
Leishmania major cathepsin L-like protease 0.0459 0.3103 0.8628
Schistosoma mansoni pyruvate kinase 0.0035 0.015 0.015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0161 0.0426
Echinococcus granulosus g protein coupled receptor 0.0038 0.0166 0.0166
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0062 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.004 0.0183 0.0183
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.053 0.3596 0.359
Echinococcus multilocularis conserved hypothetical protein 0.0025 0.0079 0.0079
Entamoeba histolytica calpain large subunit domain III containing protein 0.0044 0.0209 0.065
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0296 0.1966 0.1966
Leishmania major beta tubulin 0.0167 0.107 0.296
Schistosoma mansoni nAChR subunit 0.0145 0.0914 0.0914
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0035 0.0027
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0166 0.0166
Plasmodium vivax unspecified product 0.0138 0.0867 0.2722
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0145 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0079

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 29 % Inhibition of amyloid beta (1 to 42) (unknown origin) oligomerization assessed as reduction in intensity of experimental fluorescence plateau at 1:10 Abeta:compound ratio by thioflavin T assay based fluorescence microscopy ChEMBL. 25238173
Inhibition (binding) = 1 % Inhibition of IAPP fibril formation assessed as inhibition of aggregate formation at 1:10 protein to compound ratio by thioflavin T fluorescence assay relative to untreated control ChEMBL. 22027101

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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