Detailed information for compound 257527

Basic information

Technical information
  • TDR Targets ID: 257527
  • Name: (1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5, 7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2 -a]$b-carboline-1-carboxylic acid
  • MW: 340.416 | Formula: C20H24N2O3
  • H donors: 3 H acceptors: 3 LogP: 0.31 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)[C@H]1[C@@H](O)CC[C@@H]2[C@@H]1C[C@@H]1N(C2)CCc2c1[nH]c1c2cccc1
  • InChi: 1S/C20H24N2O3/c23-17-6-5-11-10-22-8-7-13-12-3-1-2-4-15(12)21-19(13)16(22)9-14(11)18(17)20(24)25/h1-4,11,14,16-18,21,23H,5-10H2,(H,24,25)/t11-,14-,16-,17-,18+/m0/s1
  • InChiKey: AADVZSXPNRLYLV-GKMXPDSGSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (1R,2S,4aR,13bS,14aS)-2-hydroxy-2,3,4,4a,5,6,7,8,13,13b,14,14a-dodecahydro-1H-isoquinolino[3,2-a]$b-carbolin-6-ium-1-carboxylate
  • yohimbinic acid
  • NSC 95096
  • Yohimban-16-carboxylic acid, 17-hydroxy-, (16alpha,17alpha)- (9CI)
  • Yohimbic Acid
  • Yohimbic acid [INN]
  • Prestwick3_000590
  • 17.alpha.-Hydroxyyohimban-16.alpha.-carboxylic acid
  • NSC95096
  • Yohimban-16-carboxylic acid, 17-hydroxy-, (16.alpha.,17.alpha.)-
  • Spectrum3_001117
  • SPBio_000522
  • Prestwick0_000590
  • BB_NC-0780
  • SPBio_002659
  • CHEBI:35633
  • Yohimbinsaeure
  • KBio1_001251
  • Spectrum4_001955
  • Spectrum2_000451
  • KBio3_002074
  • Prestwick2_000590
  • BSPBio_002854
  • BPBio1_000484
  • KBioSS_001995
  • Spectrum_001515
  • KBioGR_002393
  • DivK1c_006307
  • Spectrum5_000725
  • KBio2_001995
  • KBio2_004563
  • BSPBio_000440
  • KBio2_007131
  • Prestwick1_000590
  • SpecPlus_000211
  • 17alpha-Hydroxy-3alpha,15alpha,20beta-yohimban-16alpha-carbonsaeure
  • 17alpha-Hydroxyyohimban-16alpha-carboxylic acid
  • Acide yohimbique [INN-French]
  • Acido yohimbico [INN-Spanish]
  • Acidum yohimbicum [INN-Latin]
  • EINECS 208-337-7
  • ZINC03881708

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Onchocerca volvulus 0.1026 0.26 1
Loa Loa (eye worm) hypothetical protein 0.0505 0.1258 0.1258
Schistosoma mansoni microtubule-associated protein tau 0.1624 0.4142 0.4142
Brugia malayi G-protein coupled receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0105 0.0105
Echinococcus granulosus neuropeptide s receptor 0.0693 0.1741 0.1741
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0157 0.0358 0.2346
Plasmodium vivax importin-beta 2, putative 0.0035 0.0044 0.0034
Schistosoma mansoni hypothetical protein 0.0096 0.0203 0.0202
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0005
Schistosoma mansoni neuropeptide receptor 0.023 0.0548 0.0548
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0026 0.0079
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0042 0.0042
Schistosoma mansoni cytochrome P450 0.0023 0.0015 0.0014
Schistosoma mansoni neuropeptide receptor 0.023 0.0548 0.0548
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0044 0.0044
Brugia malayi mbt repeat family protein 0.0036 0.0046 0.0045
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0032 0.0031
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.023 0.0548 0.0548
Onchocerca volvulus 0.023 0.0548 0.2108
Onchocerca volvulus Alhambra homolog 0.0061 0.0112 0.0428
Brugia malayi nuclear receptor RXR 0.002 0.0006 0.0006
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.2103
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.004 0.0058 0.0058
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0071 0.0139 0.0867
Giardia lamblia Rab geranylgeranyltransferase 0.3894 1 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0015 0.006
Schistosoma mansoni lipoxygenase 0.0185 0.0432 0.0431
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0066 0.038
Leishmania major protein kinase, putative 0.0023 0.0014 0.0016
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.3894 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0165 0.0612
Loa Loa (eye worm) hypothetical protein 0.1176 0.2988 0.2988
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.023 0.0548 0.0548
Mycobacterium leprae probable conserved integral membrane transport protein 0.0096 0.0203 0.1299
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.013 0.0124
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0022 0.001 0.001
Schistosoma mansoni amine GPCR 0.023 0.0548 0.0548
Echinococcus granulosus serotonin transporter 0.049 0.1219 0.1218
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0015 0.0032
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.1026 0.26 0.2599
Loa Loa (eye worm) ACC-1 protein 0.0022 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0039 0.0054 0.0169
Loa Loa (eye worm) hypothetical protein 0.0109 0.0235 0.0235
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.0432 0.0431
Schistosoma mansoni single-minded 0.0059 0.0106 0.0105
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.016 0.0578
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0015 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.1026 0.26 0.2599
Toxoplasma gondii hypothetical protein 0.0032 0.0038 0.0051
Schistosoma mansoni lipoxygenase 0.0107 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0028 0.0027 0.0066
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.0052 0.0052
Entamoeba histolytica hypothetical protein 0.019 0.0443 0.0438
Schistosoma mansoni protein phosphatase 2C 0.0039 0.0054 0.0053
Echinococcus multilocularis fmrfamide receptor 0.023 0.0548 0.0548
Schistosoma mansoni myelin transcription factor 1 myt1 0.004 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Onchocerca volvulus Netrin receptor homolog 0.0292 0.0708 0.2724
Plasmodium falciparum importin beta, putative 0.0035 0.0044 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0052 0.0052
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0401 0.0989 0.0984
Brugia malayi hypothetical protein 0.0084 0.0171 0.017
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0022 0.001 0.001
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0505 0.1258 0.1257
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0066 0.038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0037 0.0036
Onchocerca volvulus 0.0035 0.0044 0.0166
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0022 0.001 0.001
Schistosoma mansoni glutamate synthase 0.0022 0.001 0.001
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.002 0.013
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0086 0.0295
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.007 0.0247
Mycobacterium tuberculosis Probable conserved integral membrane transport protein YjcE 0.0096 0.0203 0.1299
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.002 0.004
Onchocerca volvulus 0.0022 0.001 0.0037
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Schistosoma mansoni camp-response element binding protein 0.0061 0.0112 0.0112
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.002 0.0028
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0619
Entamoeba histolytica Ran family GTPase 0.0026 0.002 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.016 0.058
Schistosoma mansoni dopamine-beta-monooxygenase 0.2227 0.5699 0.5699
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1188 0.302 0.3019
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0048
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0059 0.0059
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0173 0.0173
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0133 0.0132
Schistosoma mansoni amine GPCR 0.0614 0.1537 0.1536
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0037 0.0036
Schistosoma mansoni DNA polymerase eta 0.0041 0.0059 0.0059
Onchocerca volvulus 0.0038 0.0052 0.0199
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.013 0.0124
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.023 0.0548 0.0548
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0068 0.013 0.0807
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0006 0.0005
Loa Loa (eye worm) bZIP transcription factor family protein 0.0061 0.0112 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0047 0.016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0028 0.0027 0.0066
Brugia malayi Protein kinase domain containing protein 0.0293 0.071 0.0709
Brugia malayi gonadotropin-releasing hormone receptor 2 0.023 0.0548 0.0548
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0067 0.0066
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0022 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0201 0.0473 0.18
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis fos transcription factor 0.0061 0.0112 0.0112
Schistosoma mansoni thyroid hormone receptor 0.0038 0.0052 0.0052
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0099 0.021 0.0209
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0066 0.0066
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0258 0.0619 0.0619
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0077 0.026
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0087 0.0177 0.0177
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0082 0.0165 0.2536
Schistosoma mansoni hypothetical protein 0.0075 0.0149 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Schistosoma mansoni sodium/chloride dependent transporter 0.049 0.1219 0.1218
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0043 0.0043
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0026 0.0063
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0054 0.0169
Schistosoma mansoni jumonji/arid domain-containing protein 0.0147 0.0333 0.0333
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0082 0.0165 0.0164
Trypanosoma brucei monoglyceride lipase, putative 0.0068 0.013 0.0478
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.3894 1 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0015 0.0018
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0056 0.0177
Mycobacterium tuberculosis Probable reductase 0.0537 0.1339 0.8958
Brugia malayi nuclear receptor NHR-88 0.0038 0.0052 0.0052
Brugia malayi neuropeptide F receptor 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0015 0.0032
Schistosoma mansoni opsin-like receptor 0.023 0.0548 0.0548
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.049 0.1219 0.1219
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0537 0.1339 0.8958
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.1026 0.26 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0165 0.8016
Mycobacterium tuberculosis Conserved protein 0.0043 0.0066 0.038
Echinococcus granulosus jun protein 0.0316 0.0768 0.0768
Brugia malayi follicle stimulating hormone receptor 0.0508 0.1265 0.1264
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.0052 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.0052 0.0052
Echinococcus granulosus expressed protein 0.0391 0.0962 0.0962
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0054
Schistosoma mansoni inositol monophosphatase 0.008 0.016 0.016
Loa Loa (eye worm) DOMON domain-containing protein 0.0225 0.0535 0.0535
Brugia malayi glutaminase DH11.1 0.033 0.0806 0.0805
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0112 0.0152
Onchocerca volvulus 0.0044 0.0067 0.0255
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.001 0.0004
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.0052 0.0052
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0066 0.0066
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.1026 0.26 0.26
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0401 0.0989 0.0984
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0022 0.001 0.001
Leishmania major monoglyceride lipase, putative 0.0068 0.013 0.0462
Schistosoma mansoni hypothetical protein 0.0713 0.1794 0.1794
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0037 0.0036
Mycobacterium ulcerans hypothetical protein 0.0026 0.002 0.013
Brugia malayi putative neuropeptide receptor NPR1 0.023 0.0548 0.0548
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0133 0.0132
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) bZIP transcription factor family protein 0.0061 0.0112 0.0112
Echinococcus granulosus G protein coupled receptor 139 0.023 0.0548 0.0548
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0142 0.1661
Schistosoma mansoni jumonji/arid domain-containing protein 0.0147 0.0333 0.0333
Schistosoma mansoni jumonji domain containing protein 0.0039 0.0054 0.0053
Plasmodium falciparum lysophospholipase, putative 0.0068 0.013 0.012
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0042 0.014
Echinococcus granulosus sodium and chloride dependent glycine 0.0258 0.0619 0.0619
Echinococcus granulosus neuropeptide receptor 0.023 0.0548 0.0548
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0165 0.8016
Echinococcus multilocularis voltage dependent calcium channel 0.0099 0.021 0.0209
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0095 0.02 0.0732
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0086 0.0086
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0022 0.001 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0015 0.0032
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0006 0.0005
Loa Loa (eye worm) programmed cell death 8 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0537 0.1339 0.8958
Brugia malayi AF-10 protein 0.002 0.0006 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0202 0.0476 0.0475
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0006 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0048 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0054 0.0169
Brugia malayi Cytochrome P450 family protein 0.0023 0.0015 0.0014
Brugia malayi PXA domain containing protein 0.002 0.0006 0.0005
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0022 0.001 0.001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3412 0.8755 0.8755
Loa Loa (eye worm) hypothetical protein 0.0099 0.021 0.021
Brugia malayi PHD-finger family protein 0.0061 0.0112 0.0111
Echinococcus multilocularis sodium channel protein 0.0043 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0077 0.0072
Loa Loa (eye worm) mbt repeat family protein 0.0036 0.0046 0.0046
Loa Loa (eye worm) latrophilin receptor protein 2 0.0075 0.0149 0.0149
Echinococcus granulosus importin subunit beta 1 0.0035 0.0044 0.0044
Leishmania major farnesyltransferase beta subunit 0.0401 0.0989 0.3781
Echinococcus granulosus mitochondrial sodium:hydrogen exchanger 9B2 0.0096 0.0203 0.0202
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0077 0.0072
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0059 0.0059
Entamoeba histolytica hypothetical protein 0.019 0.0443 0.0438
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0022 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0015 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0235 0.0561 0.2129
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0059 0.0059
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0292 0.0708 0.0708
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.001 0.0014
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0056 0.0193
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.023 0.0548 0.0548
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.016 0.0159
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.0052 0.0052
Onchocerca volvulus 0.0205 0.0484 0.1861
Brugia malayi Cation transporter family protein 0.0022 0.001 0.001
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0567 0.0567
Onchocerca volvulus 0.0022 0.001 0.0037
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0022 0.001 0.0014
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0075 0.0149 0.0148
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0015 0.006
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1176 0.2988 0.2988
Brugia malayi STAT protein, DNA binding domain containing protein 0.0101 0.0215 0.0214
Onchocerca volvulus 0.023 0.0548 0.2108
Trichomonas vaginalis rotamase, putative 0.004 0.0058 0.0052
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0066 0.038
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.3894 1 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0035 0.0035
Schistosoma mansoni rab6-interacting 0.0044 0.0067 0.0066
Echinococcus granulosus allatostatin A receptor 0.023 0.0548 0.0548
Treponema pallidum NADH oxidase 0.0082 0.0165 0.1279
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.0052 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.0096 0.0203 0.0744
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus multilocularis neuropeptides capa receptor 0.023 0.0548 0.0548
Plasmodium falciparum JmjC domain-containing protein, putative 0.0039 0.0054 0.0044
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.016 0.0154
Schistosoma mansoni adenoreceptor 0.023 0.0548 0.0548
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0109 0.0235 0.0225
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.1228 0.1228
Echinococcus multilocularis g protein coupled receptor 0.023 0.0548 0.0548
Schistosoma mansoni rab6-interacting 0.0044 0.0067 0.0066
Brugia malayi jmjC domain containing protein 0.0147 0.0333 0.0333
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0044 0.0067 0.0067
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0056 0.0076
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0015 0.006
Giardia lamblia DINP protein human, muc B family 0.0049 0.008 0.007
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0015 0.0032
Brugia malayi AKH receptor 0.023 0.0548 0.0548
Onchocerca volvulus 0.0061 0.0112 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Echinococcus granulosus nuclear factor of activated T cells 5 0.1809 0.4619 0.4619
Echinococcus multilocularis voltage dependent calcium channel 0.0099 0.021 0.0209
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0086 0.0295
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0022 0.001 0.001
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0537 0.1339 0.8958
Brugia malayi Pre-SET motif family protein 0.0032 0.0037 0.0036
Loa Loa (eye worm) glutaminase 2 0.033 0.0806 0.0806
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0007 0.0007
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0048 0.0077 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.0052 0.0052
Brugia malayi Uncoordinated protein 44 0.0292 0.0708 0.0708
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Toxoplasma gondii hypothetical protein 0.0258 0.0619 0.0842
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.1026 0.26 1
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0401 0.0989 0.0989
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0006 0.0005
Schistosoma mansoni alpha-1 adrenergic receptor 0.023 0.0548 0.0548
Leishmania major cytochrome p450-like protein 0.0023 0.0015 0.0018
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0077 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Schistosoma mansoni biogenic amine (dopamine) receptor 0.023 0.0548 0.0548
Schistosoma mansoni hypothetical protein 0.0061 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0061 0.0112 0.0112
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0015 0.0014
Echinococcus granulosus glycine receptor subunit beta 0.0022 0.001 0.001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.049 0.1219 0.1218
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0042 0.0124
Leishmania major protein farnesyltransferase alpha subunit, putative 0.1026 0.26 1
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.001 0.0017
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.002 0.002
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0059 0.0059
Mycobacterium tuberculosis Probable oxidoreductase 0.0597 0.1494 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0842
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.016 0.0154
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0258 0.0619 0.0619
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.016 0.0218
Echinococcus granulosus geminin 0.0713 0.1794 0.1794
Echinococcus multilocularis biogenic amine (5HT) receptor 0.023 0.0548 0.0548
Echinococcus multilocularis cAMP responsive element binding protein 3 0.0061 0.0112 0.0112
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0142 0.0526
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0022 0.001 0.001
Brugia malayi MH2 domain containing protein 0.0245 0.0586 0.0585
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0032 0.0032
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0031 0.0174
Plasmodium falciparum thioredoxin reductase 0.0082 0.0165 0.0155
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.01 0.01
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0044 0.0044
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0058 0.0058
Plasmodium falciparum esterase, putative 0.0068 0.013 0.012
Echinococcus granulosus glycine receptor subunit beta 0.0022 0.001 0.001
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0066 0.0708
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.01 0.01
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0112 0.0102
Loa Loa (eye worm) hypothetical protein 0.049 0.1219 0.1219
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0165 0.0612
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0109 0.0235 0.0234
Schistosoma mansoni growth hormone secretagogue receptor 0.023 0.0548 0.0548
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0061 0.0112 0.0112
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0022 0.001 0.001
Onchocerca volvulus 0.0022 0.001 0.0037
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0059 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Trichomonas vaginalis set domain proteins, putative 0.0249 0.0596 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0007 0.0007
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Plasmodium vivax prenyltransferase alpha subunit, putative 0.3894 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.0052 0.0052
Loa Loa (eye worm) calcium channel 0.0099 0.021 0.021
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.001 0.0014
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.023 0.0548 0.0548
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0042 0.0403
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0109 0.0235 0.0229
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0086 0.008
Schistosoma mansoni importin beta-1 0.0035 0.0044 0.0044
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0026 0.0016
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0086 0.0076
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni inositol monophosphatase 0.008 0.016 0.016
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0077 0.0077
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0066 0.038
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Toxoplasma gondii hypothetical protein 0.2869 0.7354 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0006 0.0006
Brugia malayi DOMON domain containing protein 0.0225 0.0535 0.0535
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Brugia malayi hypothetical protein 0.0061 0.0112 0.0112
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0027 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0015 0.0032
Brugia malayi jmjC domain containing protein 0.0039 0.0054 0.0053
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0505 0.1258 0.1257
Schistosoma mansoni sodium/hydrogen exchanger 0.0505 0.1258 0.1257
Schistosoma mansoni hypothetical protein 0.0061 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0197 0.0463 0.0463
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Giardia lamblia Rab geranylgeranyltransferase 0.0109 0.0235 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.0043 0.0066 0.0253
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0061 0.0112 0.0394
Echinococcus multilocularis jumonji domain containing 1A 0.0039 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0109 0.0235 0.0235
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0058 0.0058
Echinococcus granulosus neuropeptide Y receptor 0.023 0.0548 0.0548
Echinococcus multilocularis geminin 0.0713 0.1794 0.1794
Loa Loa (eye worm) hypothetical protein 0.0061 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0124 0.0273 0.0273
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0125 0.0277 0.1063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0476 0.0475
Loa Loa (eye worm) bZIP transcription factor family protein 0.0061 0.0112 0.0112
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0032 0.0022
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0048
Brugia malayi DOMON domain containing protein 0.0225 0.0535 0.0535
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.007 0.0247
Leishmania major mitochondrial DNA polymerase beta 0.0201 0.0473 0.1787
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0165 0.0597
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0068 0.013 0.0124
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.005 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0077 0.0277
Brugia malayi G-protein coupled receptor 0.023 0.0548 0.0548
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) DOMON domain-containing protein 0.0225 0.0535 0.0535
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0015 0.006
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0015 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.0052 0.0052
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0127 0.0172
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.023 0.0548 0.0548
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0015 0.006
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.001 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0006 0.0006
Echinococcus granulosus fmrfamide receptor 0.023 0.0548 0.0548
Brugia malayi glutathione reductase 0.0235 0.0561 0.0561
Loa Loa (eye worm) beta-lactamase 0.0043 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi Kef-type K+ transport system, membrane component 0.0096 0.0203 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.016 0.0595
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0054 0.0054
Toxoplasma gondii sodium/hydrogen exchanger NHE2 0.0096 0.0203 0.0276
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0036 0.0036
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0086 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.0052 0.0052
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.0432 0.0431
Onchocerca volvulus 0.023 0.0548 0.2108
Plasmodium falciparum lysophospholipase, putative 0.0068 0.013 0.012
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0401 0.0989 0.0984
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0295 0.0714 0.0714
Toxoplasma gondii NADPH-glutathione reductase 0.0082 0.0165 0.0224
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0022 0.001 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.0052 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0011 0.0001
Loa Loa (eye worm) cytochrome P450 0.0023 0.0015 0.0015
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0099 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0032 0.0037 0.0037
Onchocerca volvulus Putative nachr subunit 0.0022 0.001 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0052 0.0052
Trichomonas vaginalis apoptosis inducing factor, putative 0.0022 0.001 0.0004
Schistosoma mansoni biogenic amine receptor 0.023 0.0548 0.0548
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.0021 0.0021
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0015 0.0032
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0035 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0047 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0529 0.2003
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0121 0.0121
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.3894 1 1
Brugia malayi hypothetical protein 0.0122 0.027 0.0269
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0073 0.0142 0.0136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.0052 0.0052
Echinococcus granulosus lamin 0.0058 0.0105 0.0104
Onchocerca volvulus 0.0022 0.001 0.0037
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Schistosoma mansoni amine GPCR 0.023 0.0548 0.0548
Echinococcus granulosus 7TM GPCR rhodopsin 0.023 0.0548 0.0548
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0399 0.2621
Echinococcus granulosus SAM and MBT domain containing protein 0.0036 0.0046 0.0045
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0027 0.0021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0013
Schistosoma mansoni tsg101-related 0.0057 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.019 0.0443 0.0443
Echinococcus granulosus expressed protein 0.004 0.0058 0.0058
Schistosoma mansoni intermediate filament proteins 0.0058 0.0105 0.0104
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0022 0.001 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0039 0.0054 0.0186
Schistosoma mansoni voltage-gated cation channel 0.0099 0.021 0.0209
Echinococcus multilocularis snurportin 1 0.0372 0.0913 0.0913
Echinococcus multilocularis peregrin 0.0061 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0401 0.0989 0.0984
Loa Loa (eye worm) DOMON domain-containing protein 0.0225 0.0535 0.0535
Brugia malayi Melatonin receptor type 1A 0.023 0.0548 0.0548
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.1026 0.26 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.016 0.0154
Echinococcus granulosus thioredoxin glutathione reductase 0.0236 0.0563 0.0562
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0057 0.0101 0.0096
Echinococcus granulosus cpg binding protein 0.0037 0.0049 0.0048
Echinococcus granulosus neuropeptide FF receptor 2 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0015 0.006
Leishmania major hypothetical protein, conserved 0.0096 0.0203 0.0744
Toxoplasma gondii hypothetical protein 0.003 0.0031 0.0042
Echinococcus granulosus fos transcription factor 0.0061 0.0112 0.0112
Mycobacterium ulcerans hypothetical protein 0.0106 0.0227 0.2731
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0112 0.0111
Plasmodium vivax SET domain protein, putative 0.0032 0.0037 0.0027
Echinococcus multilocularis polycomb protein SCMH1 0.0036 0.0046 0.0045
Echinococcus granulosus neuropeptide receptor A26 0.0693 0.1741 0.1741
Schistosoma mansoni biogenic amine (5HT) receptor 0.023 0.0548 0.0548
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.002 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0086 0.0295
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0022 0.001 0.001
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0022 0.001 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0052 0.0052
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0401 0.0989 0.0989
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis dna polymerase kappa 0.0073 0.0142 0.0142
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.1384
Echinococcus granulosus lamin dm0 0.0058 0.0105 0.0104
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0022 0.001 0.001
Schistosoma mansoni polycystin 1-related 0.0044 0.0067 0.0066
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.001 0.0004
Onchocerca volvulus 0.0258 0.0619 0.2381
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0022 0.001 0.001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.023 0.0548 0.0548
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.016 0.0594
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0133 0.1544
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0258 0.0619 0.0619
Echinococcus granulosus axis inhibition protein axin 0.002 0.0006 0.0005
Onchocerca volvulus 0.0043 0.0066 0.0253
Loa Loa (eye worm) hypothetical protein 0.0087 0.0177 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.0052 0.0052
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.016 0.058
Echinococcus granulosus tm gpcr rhodopsin 0.1188 0.302 0.3019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0709 0.1784 0.1784
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni ran 0.0026 0.002 0.002
Entamoeba histolytica hypothetical protein 0.019 0.0443 0.0438
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0066 0.0217
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0401 0.0989 0.098
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.001 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0037 0.005
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0036 0.0046 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0071 0.0139 0.0867
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0068 0.013 0.0124
Loa Loa (eye worm) hypothetical protein 0.0096 0.0203 0.0203
Mycobacterium tuberculosis Possible lysophospholipase 0.0068 0.013 0.0807
Echinococcus multilocularis lamin dm0 0.0058 0.0105 0.0104
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.006 0.0109 0.0108
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0105 0.0368
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0022 0.001 0.001
Schistosoma mansoni hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0006 0.0005
Echinococcus granulosus histone acetyltransferase MYST2 0.004 0.0058 0.0058
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.0052 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.0238 0.0569 0.0569
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.0052 0.0052
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0082 0.0165 0.1942
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0671 0.4453
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Schistosoma mansoni neuropeptide receptor 0.023 0.0548 0.0548
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0031 0.0021
Echinococcus multilocularis alpha 1A adrenergic receptor 0.023 0.0548 0.0548
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) jmjC domain-containing protein 0.0147 0.0333 0.0333
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0006 0.0005
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0006 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0052 0.0052
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0579 0.1449 0.1448
Onchocerca volvulus 0.0043 0.0066 0.0253
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0007 0.0007
Echinococcus multilocularis serotonin transporter 0.049 0.1219 0.1218
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1176 0.2988 0.2988
Echinococcus multilocularis somatostatin receptor 0.023 0.0548 0.0548
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0084 0.0286
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.016 0.0578
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0075 0.0149 0.0148
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0063 0.0062
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.008 0.0286
Treponema pallidum sodium- and chloride- dependent transporter 0.049 0.1219 1
Loa Loa (eye worm) hypothetical protein 0.0505 0.1258 0.1258
Brugia malayi hypoxia-induced factor 1 0.0182 0.0423 0.0423
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.004
Echinococcus granulosus orexin receptor type 2 0.023 0.0548 0.0548
Brugia malayi RE15519p 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.01 0.061
Mycobacterium tuberculosis Probable dehydrogenase 0.0537 0.1339 0.8958
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0022 0.001 0.001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0258 0.0619 0.0619
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.002 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.023 0.0548 0.0548
Leishmania major DNA polymerase eta, putative 0.0041 0.0059 0.0191
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0142 0.051
Loa Loa (eye worm) inositol-1 0.008 0.016 0.016
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0099 0.021 0.0209
Toxoplasma gondii Na+/H+ exchanger NHE3 0.0096 0.0203 0.0276
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0015 0.0032
Brugia malayi Serotonin receptor 0.023 0.0548 0.0548
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0165 0.0597
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0109 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Schistosoma mansoni glutamate synthase 0.0022 0.001 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0054 0.0054
Entamoeba histolytica disulphide oxidoreductase, putative 0.0022 0.001 0.0004
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0066 0.0708
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0021 0.0021
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0292 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0505 0.1258 0.1258
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Brugia malayi Cytochrome P450 family protein 0.0034 0.0042 0.0042
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0049 0.008 0.027
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0096 0.0203 0.1299
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.0096 0.0203 0.0744
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.014 0.0315 0.0315
Schistosoma mansoni glutaminase 0.033 0.0806 0.0805
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.0476 0.0475
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0048 0.0077 0.0072
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1176 0.2988 0.2988
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0039 0.0054 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Echinococcus multilocularis expressed protein 0.004 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.0177 0.0241
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0015 0.0032
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0042 0.0042
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0316 0.0768 0.0768
Schistosoma mansoni neuropeptide F-like receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0238 0.0567 0.0567
Echinococcus granulosus single minded 2 0.0047 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Trypanosoma cruzi lanosterol synthase, putative 0.0157 0.0358 0.1344
Brugia malayi CXXC zinc finger family protein 0.0035 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0011
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0066 0.0066
Brugia malayi cytochrome P450 0.0023 0.0015 0.0014
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.001 0.001
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0021 0.0021
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0099 0.021 0.0209
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0031 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Entamoeba histolytica thioredoxin reductase, putative 0.0022 0.001 0.0004
Schistosoma mansoni amine GPCR 0.023 0.0548 0.0548
Loa Loa (eye worm) STAT protein 0.0101 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0054
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0505 0.1258 0.1257
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0066 0.038
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0505 0.1258 0.1257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0037 0.0036
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.023 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Trypanosoma cruzi hypothetical protein, conserved 0.1026 0.26 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0133 0.1544
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0059 0.0059
Brugia malayi Sodium/hydrogen exchanger 8 0.0096 0.0203 0.0202
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni fos transcription factor-related 0.0061 0.0112 0.0112
Leishmania major hypothetical protein, conserved 0.0027 0.0023 0.0052
Echinococcus multilocularis glutamate synthase 0.0022 0.001 0.001
Leishmania major DNA polymerase kappa, putative 0.0049 0.008 0.027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0052 0.0052
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0401 0.0989 0.0989
Echinococcus multilocularis tachykinin peptides receptor 99D 0.023 0.0548 0.0548
Echinococcus granulosus lysine specific demethylase 5A 0.0147 0.0333 0.0333
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Toxoplasma gondii hypothetical protein 0.1026 0.26 0.3535
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0032 0.0032
Loa Loa (eye worm) solute carrier family 6 member 4 0.049 0.1219 0.1219
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.0052 0.0052
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.012 0.0423
Echinococcus multilocularis SAM and MBT domain containing protein 0.0036 0.0046 0.0045
Trichomonas vaginalis hypothetical protein 0.0041 0.006 0.0054
Echinococcus granulosus g protein coupled receptor 0.023 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0052 0.0052
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0082 0.0165 0.1942
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0238 0.0569 0.0569
Trypanosoma cruzi protein farnesyltransferase, putative 0.0401 0.0989 0.3781
Brugia malayi Cation transporter family protein 0.0022 0.001 0.001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0022 0.001 0.001
Onchocerca volvulus 0.0251 0.0601 0.2312
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0401 0.0989 0.0984
Echinococcus multilocularis G-protein coupled receptor, putative 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0216 0.0511 0.0511
Echinococcus multilocularis jun protein 0.0316 0.0768 0.0768
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0505 0.1258 0.1258
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Brugia malayi jmjC domain containing protein 0.0271 0.0654 0.0653
Loa Loa (eye worm) neuropeptide F receptor 0.023 0.0548 0.0548
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.016 0.1887
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0022 0.001 0.001
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.003 0.0032 0.0043
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.01 0.061
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0021 0.0007 0.001
Onchocerca volvulus 0.0022 0.001 0.0037
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0067 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0047 0.016
Leishmania major cytochrome p450-like protein 0.0023 0.0015 0.0018
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0015 0.0018
Echinococcus granulosus biogenic amine 5HT receptor 0.023 0.0548 0.0548
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0059 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.0096 0.0203 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei protein kinase, putative 0.0051 0.0086 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.0052 0.0052
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0026 0.0016
Echinococcus granulosus 7tm_1 domain containing protein 0.023 0.0548 0.0548
Schistosoma mansoni tsg101-related 0.007 0.0135 0.0134
Loa Loa (eye worm) G-protein coupled receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) ACC-1 protein 0.0022 0.001 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.023 0.0548 0.0548
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Onchocerca volvulus 0.023 0.0548 0.2108
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0034 0.0043 0.0128
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0316 0.0768 0.0768
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.012 0.0423
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0022 0.001 0.001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.001 0.001
Brugia malayi beta-lactamase 0.0043 0.0066 0.0066
Brugia malayi bZIP transcription factor family protein 0.0061 0.0112 0.0112
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0059 0.0191
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.023 0.0548 0.0548
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0258 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0125 0.0277 0.0277
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Plasmodium falciparum glutathione reductase 0.0082 0.0165 0.0155
Echinococcus multilocularis neuropeptide s receptor 0.0693 0.1741 0.1741
Echinococcus multilocularis serotonin receptor 0.023 0.0548 0.0548
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0401 0.0989 0.0984
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0011 0.0001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0082 0.0165 0.0224
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0505 0.1258 0.1257
Toxoplasma gondii hypothetical protein 0.0258 0.0619 0.0842
Schistosoma mansoni neuropeptide f receptor 76f 0.023 0.0548 0.0548
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.007
Echinococcus multilocularis thyroid hormone receptor alpha 0.0038 0.0052 0.0052
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.023 0.0548 0.0548
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0005
Mycobacterium ulcerans glutaminase 0.033 0.0806 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.0044 0.0067 0.0066
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.1026 0.26 0.2595
Echinococcus multilocularis glycine receptor subunit beta 0.0022 0.001 0.001
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0292 0.0708 0.0708
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.016 0.0578
Schistosoma mansoni biogenic amine (dopamine) receptor 0.023 0.0548 0.0548
Mycobacterium ulcerans beta-lactamase 0.0043 0.0066 0.0708
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.002 0.0014
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0109 0.0235 0.0225
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0087 0.0177 0.0167
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0061 0.0112 0.0112
Echinococcus multilocularis sodium:hydrogen exchanger 0.0505 0.1258 0.1257
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0142 0.0526
Brugia malayi Dopamine receptor protein 1 0.023 0.0548 0.0548
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0079 0.0079
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0423 0.0423
Echinococcus multilocularis g protein coupled receptor 0.023 0.0548 0.0548
Schistosoma mansoni tsg101-related 0.007 0.0135 0.0134
Schistosoma mansoni hypothetical protein 0.0713 0.1794 0.1794
Entamoeba histolytica hypothetical protein 0.0028 0.0027 0.0021
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.2745
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0022 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0027 0.0026
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis sex peptide receptor 0.023 0.0548 0.0548
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.0052 0.0052
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0063 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0142 0.051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0057 0.0102 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0086 0.0086
Onchocerca volvulus 0.0022 0.001 0.0037
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.008 0.016 0.7788
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0258 0.0619 0.0619
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0476 0.0475
Brugia malayi Pre-SET motif family protein 0.0219 0.0518 0.0518
Mycobacterium ulcerans lysophospholipase 0.0068 0.013 0.1505
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.0052 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0202 0.0476 0.0475
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0022 0.001 0.001
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.3894 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0086 0.008
Onchocerca volvulus 0.0022 0.001 0.0037
Plasmodium vivax geranylgeranyltransferase, putative 0.0109 0.0235 0.0225
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.0177 0.0241
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0027 0.0021
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0077 0.0077
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.002 0.001
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0109 0.0235 0.0884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.3894 1 1
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0022 0.001 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0709 0.1784 0.1784
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Echinococcus granulosus tachykinin peptides receptor 99D 0.023 0.0548 0.0548
Echinococcus multilocularis allatostatin A receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) neuropeptide F receptor 0.023 0.0548 0.0548
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0032 0.0022
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0059 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0066 0.006
Echinococcus multilocularis fmrfamide receptor 0.023 0.0548 0.0548
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.016 0.0154
Onchocerca volvulus 0.0048 0.0079 0.0303
Echinococcus granulosus jumonji domain containing 1A 0.0039 0.0054 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0027 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Onchocerca volvulus 0.0225 0.0535 0.2057
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0058 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0235 0.0868
Echinococcus granulosus neuropeptide Y receptor 0.023 0.0548 0.0548
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Echinococcus granulosus inositol monophosphatase 1 0.008 0.016 0.016
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Brugia malayi Doublecortin family protein 0.0044 0.0067 0.0066
Brugia malayi Dopamine receptor protein 2 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0059
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0022 0.001 0.001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0015 0.006
Schistosoma mansoni sodium/chloride dependent transporter 0.0258 0.0621 0.062
Loa Loa (eye worm) glutathione reductase 0.0235 0.0561 0.0561
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.1026 0.26 0.2592
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.004
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0133 0.0132
Brugia malayi Serotonin receptor 0.0763 0.1921 0.1921
Schistosoma mansoni survival motor neuron protein 0.0048 0.0079 0.0079
Plasmodium falciparum amino acid transporter, putative 0.0258 0.0619 0.061
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.3894 1 1
Loa Loa (eye worm) hypothetical protein 0.1176 0.2988 0.2988
Echinococcus multilocularis g-protein coupled receptor 0.023 0.0548 0.0548
Echinococcus granulosus nAChR subunit 0.0022 0.001 0.001
Schistosoma mansoni opsin-like receptor 0.023 0.0548 0.0548
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0066 0.0066
Schistosoma mansoni glutamate synthase 0.0022 0.001 0.001
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni hypothetical protein 0.0494 0.1228 0.1228
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni ran 0.0026 0.002 0.002
Echinococcus multilocularis conserved hypothetical protein 0.1492 0.3803 0.3803
Brugia malayi bZIP transcription factor family protein 0.0316 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0024
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0235 0.0868
Giardia lamblia PHD finger protein 15 0.0061 0.0112 0.0102
Mycobacterium tuberculosis Conserved protein 0.0043 0.0066 0.038
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0032 0.0032
Brugia malayi GnHR receptor homolog 0.023 0.0548 0.0548
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0006 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0005
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0031 0.0142
Brugia malayi steroid hormone receptor 0.0038 0.0052 0.0052
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.016 0.0159
Echinococcus multilocularis phd:f box containing protein 0.0039 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0163 0.0375 0.0374
Mycobacterium tuberculosis Conserved protein 0.0026 0.002 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Echinococcus multilocularis lysine specific demethylase 6a 0.0039 0.0054 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.0052 0.0052
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0048 0.0077 0.026
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0056 0.005
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0401 0.0989 0.3791
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.023 0.0548 0.0548
Echinococcus multilocularis ubiquitin specific protease 41 0.0048 0.0077 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0059 0.0059
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0258 0.0619 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.013 0.0124
Brugia malayi glutamate synthase 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.0096 0.0203 0.0744
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0015 0.0035
Brugia malayi Bromodomain containing protein 0.0061 0.0112 0.0111
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus axis inhibition protein axin 0.002 0.0006 0.0005
Onchocerca volvulus 0.0112 0.0244 0.0938
Brugia malayi Cytochrome P450 family protein 0.0081 0.0163 0.0163
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1176 0.2988 0.2988
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.002 0.002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0067 0.0066
Brugia malayi hypothetical protein 0.0238 0.0567 0.0567
Echinococcus granulosus neuropeptides capa receptor 0.023 0.0548 0.0548
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.016 0.058
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0015 0.0032
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0082 0.0165 0.0155
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.0052 0.0199
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0082 0.0165 0.0164
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0022 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium ulcerans lipase LipD 0.0043 0.0066 0.0708
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0015 0.0032
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0087 0.0177 0.1128
Schistosoma mansoni amine GPCR 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0059 0.0053
Echinococcus multilocularis G protein coupled receptor 139 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0015 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0052 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0015 0.006
Schistosoma mansoni cpg binding protein 0.0035 0.0044 0.0043
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0133 0.0132
Leishmania major geranylgeranyltransferase, putative 0.0109 0.0235 0.0868
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0258 0.0619 0.0619
Echinococcus granulosus phd:f box containing protein 0.0039 0.0054 0.0053
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0032 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Echinococcus granulosus g protein coupled receptor 0.023 0.0548 0.0548
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0024
Echinococcus granulosus JmjC domain containing protein 4 0.0039 0.0054 0.0053
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.001 0.001
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.016 0.0159
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0082 0.0165 0.0612
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0015 0.006
Leishmania major hypothetical protein, conserved 0.0223 0.0529 0.2003
Onchocerca volvulus 0.023 0.0548 0.2108
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Onchocerca volvulus 0.0096 0.0203 0.0778
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0006 0.0005
Echinococcus granulosus cAMP responsive element binding protein 3 0.0061 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.0052 0.0052
Brugia malayi ORL1-like opioid receptor 0.023 0.0548 0.0548
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0109 0.0235 0.0229
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.002 0.002
Echinococcus multilocularis orexin receptor type 2 0.023 0.0548 0.0548
Brugia malayi DOMON domain containing protein 0.0225 0.0535 0.0535
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0109 0.0235 0.0234
Schistosoma mansoni hypothetical protein 0.0372 0.0913 0.0913
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0109 0.0235 0.0234
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0048 0.0077 0.0077
Trypanosoma cruzi trypanothione reductase, putative 0.0082 0.0165 0.0597
Brugia malayi Death domain containing protein 0.0292 0.0708 0.0708
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0037 0.0036
Echinococcus granulosus sodium and chloride dependent glycine 0.0258 0.0619 0.0619
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0072 0.0071
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0077 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.0052 0.0052
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0109 0.0235 0.0234
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus glycine receptor subunit alpha 1 0.0022 0.001 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0086 0.008
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0401 0.0989 0.098
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0095 0.02 0.0747
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0048 0.0077 0.0077
Trypanosoma brucei hypothetical protein, conserved 0.0223 0.0529 0.2016
Echinococcus granulosus RUN 0.0044 0.0067 0.0066
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0238 0.0569 0.0569
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0109 0.0235 0.0229
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0505 0.1258 0.1257
Echinococcus multilocularis RUN 0.0044 0.0067 0.0066
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0082 0.0165 0.0612
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0537 0.1339 0.8958
Loa Loa (eye worm) glutaminase 0.033 0.0806 0.0806
Loa Loa (eye worm) hypothetical protein 0.003 0.0032 0.0032
Echinococcus granulosus glycine receptor subunit alpha 1 0.0022 0.001 0.001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0597 0.1494 1
Brugia malayi Inositol-1 0.008 0.016 0.016
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.001 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0235 0.0561 0.3716
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.023 0.0548 0.0548
Echinococcus granulosus microtubule associated protein 2 0.1624 0.4142 0.4142
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0006 0.0005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0022 0.001 0.001
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0133 0.0474
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0597 0.1494 1
Plasmodium falciparum phd finger protein, putative 0.0061 0.0112 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Echinococcus multilocularis netrin receptor unc 5 0.0292 0.0708 0.0708
Schistosoma mansoni opsin-like receptor 0.023 0.0548 0.0548
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0039 0.0054 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0015 0.006
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0082 0.0165 0.0164
Mycobacterium leprae Probable lipase LipE 0.0043 0.0066 0.038
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.002 0.001
Schistosoma mansoni phd/f-box containing protein 0.0039 0.0054 0.0053
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0096 0.0203 0.0202
Brugia malayi larval opioid receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0254 0.061 0.061
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0112 0.0112
Loa Loa (eye worm) norepinephrine transporter 0.049 0.1219 0.1219
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0443 0.0443
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.002 0.013
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0015 0.006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0028 0.0027 0.0066
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0044 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0044 0.0067 0.0066
Onchocerca volvulus 0.023 0.0548 0.2108
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.0865 0.0855
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0086 0.008
Trichomonas vaginalis glutaminase, putative 0.033 0.0806 0.08
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.023 0.0548 0.2108
Toxoplasma gondii sodium/hydrogen exchanger 3 protein 0.0096 0.0203 0.0276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.0027 0.0024 0.0024
Echinococcus granulosus sex peptide receptor 0.023 0.0548 0.0548
Trichomonas vaginalis ran, putative 0.0026 0.002 0.0014
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0026 0.0063
Onchocerca volvulus 0.023 0.0548 0.2108
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.023 0.0548 0.0548
Leishmania major cathepsin L-like protease 0.0064 0.012 0.0423
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.0586 0.0586
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.3894 1 1
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0006 0.0006
Echinococcus multilocularis histone acetyltransferase MYST2 0.004 0.0058 0.0058
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0015 0.0018
Schistosoma mansoni camp-response element binding protein-related 0.0061 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0035 0.0044 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0013 0.0017
Onchocerca volvulus 0.023 0.0548 0.2108
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.013 0.0124
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0058 0.0058
Trichomonas vaginalis mercuric reductase, putative 0.0082 0.0165 0.0159
Mycobacterium ulcerans potassium/proton antiporter 0.0096 0.0203 0.2423
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0401 0.0989 0.0984
Echinococcus multilocularis neuropeptide FF receptor 2 0.023 0.0548 0.0548
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0142 0.1661
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0046 0.0045
Plasmodium vivax hypothetical protein, conserved 0.0258 0.0619 0.061
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0105 0.0104
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0067 0.0067
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0082 0.0165 0.0597
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0027 0.0023 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0052 0.0052
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0061 0.0112 0.0112
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0258 0.0619 0.0619
Echinococcus multilocularis GPCR, family 2 0.0075 0.0149 0.0148
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0077 0.0072
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.3894 1 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0082 0.0165 0.0155
Brugia malayi PXA domain containing protein 0.002 0.0006 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0022 0.001 0.001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0099 0.021 0.0209
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0044 0.0148
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0443 0.0443
Leishmania major lanosterol synthase, putative 0.0048 0.0077 0.026
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0292 0.0708 0.0708
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0015 0.0032
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0597 0.1494 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.0052 0.0199
Plasmodium vivax PST-A protein 0.0068 0.013 0.012
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0061 0.0112 0.0112
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.1026 0.26 0.2599
Echinococcus multilocularis glycine receptor subunit beta 0.0022 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.0476 0.0475
Brugia malayi mbt repeat family protein 0.0036 0.0046 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0052 0.0052
Onchocerca volvulus 0.0258 0.0619 0.2381
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0075 0.0149 0.0148
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0061 0.0112 0.041
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0086 0.0295
Brugia malayi jmjC domain containing protein 0.0039 0.0054 0.0053
Plasmodium vivax thioredoxin reductase, putative 0.0235 0.0561 0.0552
Echinococcus multilocularis microtubule associated protein 2 0.1624 0.4142 0.4142
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0022 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0037 0.0036
Echinococcus granulosus neuropeptide receptor 0.023 0.0548 0.0548
Schistosoma mansoni hypothetical protein 0.0048 0.0079 0.0079
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0401 0.0989 0.0989
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.023 0.0548 0.0548
Trypanosoma brucei unspecified product 0.0028 0.0027 0.0081
Schistosoma mansoni hypothetical protein 0.0075 0.0149 0.0148
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0066 0.006
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0508 0.1265 0.1265
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0066 0.0234
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.013 0.0124
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0066 0.038
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.3894 1 1
Echinococcus granulosus sodium:hydrogen exchanger 0.0505 0.1258 0.1257
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0022 0.001 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0122 0.0447
Loa Loa (eye worm) hypothetical protein 0.0163 0.0375 0.0375
Entamoeba histolytica hypothetical protein 0.019 0.0443 0.0438
Loa Loa (eye worm) hypothetical protein 0.0096 0.0203 0.0203
Loa Loa (eye worm) serotonin transporter b 0.049 0.1219 0.1219
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0066 0.0066
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.016 0.016
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Brugia malayi putative neuropeptide receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Echinococcus granulosus g protein coupled receptor 0.023 0.0548 0.0548
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.0052 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.1026 0.26 1
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0505 0.1258 0.4838
Brugia malayi PHD-finger family protein 0.0022 0.0011 0.001
Schistosoma mansoni sulfide quinone reductase 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.0052 0.0052
Loa Loa (eye worm) MBCTL1 0.004 0.0058 0.0058
Onchocerca volvulus 0.023 0.0548 0.2108
Schistosoma mansoni coup transcription factor 0.0038 0.0052 0.0052
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0295 0.0714 0.0714
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0027 0.0023 0.0068
Mycobacterium leprae putative cytochrome p450 0.0023 0.0015 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0044 0.0148
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0039 0.0054 0.0053
Echinococcus granulosus GPCR family 2 0.0075 0.0149 0.0148
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0913 0.0913
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0022 0.001 0.001
Brugia malayi Tachykinin-like peptides receptor 99D 0.023 0.0548 0.0548
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.004
Echinococcus multilocularis sodium:hydrogen exchanger 7 0.0096 0.0203 0.0202
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.001 0.0004
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0086 0.0086
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0006 0.0005
Schistosoma mansoni disulfide oxidoreductase 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0238 0.0569 0.0569
Echinococcus multilocularis nuclear factor of activated T cells 5 0.1809 0.4619 0.4619
Loa Loa (eye worm) RGS-3 protein 0.002 0.0006 0.0006
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0505 0.1258 0.4838
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.004 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.1026 0.26 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0082 0.0165 0.1042
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0015 0.0032
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.2869 0.7354 0.7353
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0022 0.001 0.001
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0505 0.1258 0.1257
Brugia malayi Cytochrome P450 family protein 0.0034 0.0042 0.0042
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0201 0.0473 0.1787
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0063 0.0062
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0022 0.001 0.001
Schistosoma mansoni jumonji domain containing protein 0.023 0.0547 0.0547
Schistosoma mansoni hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0066 0.0066
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Brugia malayi Thioredoxin reductase 0.0235 0.0561 0.0561
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.0052 0.0052
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.0052 0.0052
Schistosoma mansoni histamine h1 receptor 0.023 0.0548 0.0548
Echinococcus granulosus protein prenyltransferase alpha subunit 0.1026 0.26 0.2599
Leishmania major hypothetical protein, conserved 0.0028 0.0026 0.0063
Loa Loa (eye worm) melatonin receptor type 1A 0.023 0.0548 0.0548
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0597 0.1494 0.1494
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.0096 0.0203 0.0744
Leishmania major Na/H antiporter-like protein 0.0096 0.0203 0.0744
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0015 0.006
Trypanosoma brucei unspecified product 0.0028 0.0027 0.0081
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0006 0.0005
Schistosoma mansoni sulfide quinone reductase 0.0022 0.001 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0142 0.051
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Echinococcus granulosus Ankyrin 0.0295 0.0714 0.0714
Schistosoma mansoni sodium/chloride dependent transporter 0.0258 0.0619 0.0619
Brugia malayi hypothetical protein 0.0027 0.0024 0.0024
Schistosoma mansoni Slc9a7 protein 0.0096 0.0203 0.0202
Brugia malayi G protein-coupled receptor F59B2.13 0.023 0.0548 0.0548
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0015 0.006
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0022 0.001 0.001
Onchocerca volvulus 0.049 0.1219 0.4686
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0067 0.0066
Echinococcus granulosus dnaJ subfamily B 0.0494 0.1228 0.1228
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.016 0.0154
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.001 0.001
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0007 0.0007
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.1026 0.26 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1176 0.2988 0.2988
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0022 0.001 0.001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.023 0.0548 0.0548
Plasmodium vivax amine transporter, putative 0.0258 0.0619 0.061
Brugia malayi nuclear hormone receptor 0.0038 0.0052 0.0052
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.023 0.0548 0.0548
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0095 0.02 0.0732
Echinococcus granulosus serotonin receptor 0.023 0.0548 0.0548
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0086 0.0311
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus cyclic AMP dependent transcription factor ATF 6 0.0061 0.0112 0.0112
Onchocerca volvulus 0.023 0.0548 0.2108
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.0052 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0015 0.0032
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0147 0.0146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0202 0.0476 0.0475
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.012 0.0423
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0096 0.0203 0.0202
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.001 0.0004
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.023 0.0548 0.2108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0142 0.051
Schistosoma mansoni sodium-dependent amino acid transporter 0.0258 0.0619 0.0619
Trypanosoma cruzi lanosterol synthase, putative 0.0157 0.0358 0.1344
Schistosoma mansoni hypothetical protein 0.0267 0.0642 0.0641
Schistosoma mansoni lamin 0.0058 0.0105 0.0104
Echinococcus granulosus dna polymerase kappa 0.0073 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0399 0.4888
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0006 0.0005
Brugia malayi bZIP transcription factor family protein 0.0061 0.0112 0.0112
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0015 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0112 0.0152
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0028 0.0027 0.0082
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0056 0.0177
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0084 0.0171 0.017
Loa Loa (eye worm) thioredoxin reductase 0.0235 0.0561 0.0561
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0022 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.023 0.0548 0.0548
Schistosoma mansoni hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0073 0.0073
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0059 0.0333
Echinococcus multilocularis dna polymerase eta 0.0041 0.0059 0.0059
Schistosoma mansoni camp-response element binding protein-related 0.0061 0.0112 0.0112
Onchocerca volvulus 0.0258 0.0619 0.2381
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0086 0.0295
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0022 0.001 0.001
Echinococcus granulosus endonuclease exonuclease phosphatase 0.014 0.0315 0.0315
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1789 0.4569 0.4569
Plasmodium falciparum transporter, putative 0.0258 0.0619 0.061
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0109 0.0235 0.0319
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0022 0.001 0.001
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0505 0.1258 0.4838
Echinococcus multilocularis lamin 0.0058 0.0105 0.0104
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.002 0.004
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0068 0.013 0.0124
Plasmodium falciparum geranylgeranyltransferase, putative 0.0109 0.0235 0.0225
Trypanosoma brucei monoglyceride lipase, putative 0.0068 0.013 0.0478
Loa Loa (eye worm) LGC-31 protein 0.0022 0.001 0.001
Plasmodium vivax JmjC domain containing protein 0.0039 0.0054 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0258 0.0619 0.0619
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0046 0.0045
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.023 0.0548 0.0548
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.0586 0.0586
Brugia malayi G protein-coupled receptor 0.023 0.0548 0.0548
Brugia malayi beta-lactamase family protein 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0075 0.0149 0.0149
Echinococcus granulosus ubiquitin specific protease 41 0.0048 0.0077 0.0077
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0075 0.0149 0.0148
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.1026 0.26 1
Schistosoma mansoni axis inhibition protein axin 0.002 0.0006 0.0005
Brugia malayi Dopamine receptor 0.023 0.0548 0.0548
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0202 0.0476 0.0475
Schistosoma mansoni peptidase Clp (S14 family) 0.0087 0.0177 0.0177
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0109 0.0235 0.0868
Echinococcus granulosus thyrotropin releasing hormone receptor 0.023 0.0548 0.0548
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0401 0.0989 0.1345
Schistosoma mansoni biogenic amine receptor 0.023 0.0548 0.0548
Echinococcus granulosus glycine receptor subunit alpha 1 0.0022 0.001 0.001
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0173 0.0173
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0067 0.0057
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.8679
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0066 0.0217
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.016 0.016
Trypanosoma brucei NADH dehydrogenase 0.0022 0.001 0.0017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0052 0.0052
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0022 0.001 0.001
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0022 0.001 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.0052 0.0052
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.0052 0.0052
Loa Loa (eye worm) TYRA-2 protein 0.023 0.0548 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.0052 0.0052
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0082 0.0165 0.0597
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0061 0.0112 0.0112
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0075 0.0149 0.0148
Plasmodium vivax glutathione reductase, putative 0.0235 0.0561 0.0552
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0026 0.0036
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.1026 0.26 1
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0037 0.0036
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.0013 0.0012
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0006 0.0005
Onchocerca volvulus 0.0058 0.0105 0.0401
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0105 0.0105
Echinococcus granulosus snurportin 1 0.0372 0.0913 0.0913
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0007 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0026 0.0016
Trypanosoma brucei unspecified product 0.0065 0.0122 0.0447
Brugia malayi Importin beta-1 subunit 0.0035 0.0044 0.0044
Echinococcus multilocularis 0.0023 0.0015 0.0014
Plasmodium falciparum glutathione reductase 0.0235 0.0561 0.0552
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0099 0.021 0.0209
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0842
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.2745
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0058 0.0052
Schistosoma mansoni lamin 0.0058 0.0105 0.0104
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0567 0.0567
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Brugia malayi N-terminal motif family protein 0.0125 0.0277 0.0276
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0099 0.021 0.0209
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0537 0.1339 0.8958
Leishmania major importin beta-1 subunit, putative 0.0028 0.0027 0.0066
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.013 0.0124
Brugia malayi hypothetical protein 0.0044 0.0067 0.0066
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0021 0.0021
Trypanosoma brucei trypanothione reductase 0.0235 0.0561 0.2142
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0015 0.006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0082 0.0165 0.1942
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.01 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.013 0.0124
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0022 0.001 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0077 0.0077
Schistosoma mansoni rotamase 0.004 0.0058 0.0058
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0022 0.001 0.001
Schistosoma mansoni hypothetical protein 0.003 0.0032 0.0032
Trichomonas vaginalis glutathione reductase, putative 0.0082 0.0165 0.0159
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0399 0.2621
Brugia malayi Serotonin/octopamine receptor family protein 7 0.023 0.0548 0.0548
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0066 0.038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0031 0.003
Toxoplasma gondii ABC1 family protein 0.0043 0.0066 0.009
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus granulosus glutamate synthase 0.0022 0.001 0.001
Echinococcus multilocularis musashi 0.0058 0.0105 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0006 0.0006
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0112 0.0111
Schistosoma mansoni ankyrin 23/unc44 0.0292 0.0708 0.0708
Leishmania major cytochrome p450-like protein 0.0034 0.0042 0.0124
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0022 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.023 0.0548 0.0548
Schistosoma mansoni neuropeptide receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis sodium and chloride dependent glycine 0.0258 0.0619 0.0619
Echinococcus multilocularis mitochondrial sodium:hydrogen exchanger 9B2 0.0096 0.0203 0.0202
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0036 0.0046 0.0174
Toxoplasma gondii Na+/H+ exchanger NHE1 0.0096 0.0203 0.0276
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.004 0.0058 0.0058
Mycobacterium ulcerans hypothetical protein 0.0026 0.002 0.013
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.001 0.0017
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0021 0.0021
Echinococcus granulosus somatostatin receptor 0.023 0.0548 0.0548
Giardia lamblia Rab geranylgeranyltransferase 0.1026 0.26 0.2592
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0022 0.001 0.001
Leishmania major trypanothione reductase 0.0235 0.0561 0.2129
Echinococcus granulosus voltage dependent calcium channel 0.0099 0.021 0.0209
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0409 0.1009 0.1009
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.1026 0.26 0.2592
Echinococcus granulosus tm gpcr rhodopsin 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0027
Trichomonas vaginalis esterase, putative 0.0043 0.0066 0.006
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.2103
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0022 0.001 0.0004
Toxoplasma gondii selenide, water dikinase 0.0022 0.001 0.0014
Brugia malayi neuropeptide F receptor 0.023 0.0548 0.0548
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0258 0.0619 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0133 0.0828
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0044 0.006
Echinococcus multilocularis neuropeptide receptor 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.023 0.0548 0.0548
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.019 0.0443 0.0443
Onchocerca volvulus 0.0044 0.0067 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.1026 0.26 0.2595
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0054 0.0054
Onchocerca volvulus 0.0032 0.0037 0.014
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0066 0.006
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0022 0.001 0.001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0106 0.0227 0.1465
Echinococcus granulosus dro:myosuppressin receptor 0.023 0.0548 0.0548
Brugia malayi ecdysteroid receptor 0.0038 0.0052 0.0052
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.023 0.0548 0.0548
Echinococcus granulosus biogenic amine 5HT receptor 0.023 0.0548 0.0548
Echinococcus granulosus tm gpcr rhodopsin 0.023 0.0548 0.0548
Schistosoma mansoni camp-response element binding protein-related 0.0061 0.0112 0.0112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Echinococcus multilocularis nAChR subunit 0.0022 0.001 0.001
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0087 0.0177 0.0177
Schistosoma mansoni nAChR subunit 0.0022 0.001 0.001
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0505 0.1258 0.1258
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0015 0.006
Mycobacterium ulcerans hypothetical protein 0.0043 0.0066 0.0708
Trypanosoma cruzi monoglyceride lipase, putative 0.0068 0.013 0.0462
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0066 0.0056
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Brugia malayi bZIP transcription factor family protein 0.0061 0.0112 0.0112
Schistosoma mansoni myosin xvIII 0.023 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0409 0.1009 0.1009
Echinococcus multilocularis JmjC domain containing protein 4 0.0039 0.0054 0.0053
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.0865 0.7071
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0109 0.0235 0.0234
Echinococcus multilocularis cyclic AMP dependent transcription factor ATF 6 0.0061 0.0112 0.0112
Onchocerca volvulus 0.0096 0.0203 0.0778
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0075 0.0149 0.0148
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus granulosus expressed protein 0.0061 0.0112 0.0112
Schistosoma mansoni peptidylglycine monooxygenase 0.1176 0.2988 0.2988
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0082 0.0165 0.0164
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0082 0.0165 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0865 0.0859
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.023 0.0548 0.0548
Echinococcus granulosus lysine specific demethylase 6a 0.0039 0.0054 0.0053
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0292 0.0708 0.0699
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0066 0.006
Loa Loa (eye worm) hypothetical protein 0.049 0.1219 0.1219
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Brugia malayi latrophilin 2 splice variant baaae 0.0163 0.0375 0.0374
Trypanosoma brucei lanosterol synthase 0.0157 0.0358 0.1358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.023 0.0548 0.0548
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0106 0.0105
Brugia malayi hypothetical protein 0.0258 0.0619 0.0619
Brugia malayi PAS domain containing protein 0.0059 0.0106 0.0105
Leishmania major GTP-binding protein, putative 0.0026 0.002 0.004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0006 0.0006
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0619
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0006 0.0005
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0006 0.0005
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0022 0.001 0.001
Loa Loa (eye worm) voltage-dependent calcium channel 0.0023 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Brugia malayi intermediate filament protein 0.0058 0.0105 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.001 0.001
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) hypothetical protein 0.0112 0.0244 0.0244
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0015 0.006
Brugia malayi jmjC domain containing protein 0.0039 0.0054 0.0053
Trichomonas vaginalis rotamase, putative 0.0039 0.0056 0.005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.023 0.0548 0.0548
Schistosoma mansoni loxhd1 0.0044 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0292 0.0708 0.0708
Brugia malayi RNA, U transporter 1 0.0099 0.021 0.0209
Leishmania major cathepsin L-like protease 0.0064 0.012 0.0423
Leishmania major cathepsin L-like protease 0.0064 0.012 0.0423
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.023 0.0548 0.0548
Brugia malayi beta-lactamase family protein 0.0043 0.0066 0.0066
Plasmodium falciparum lysophospholipase, putative 0.0068 0.013 0.012
Brugia malayi Latrophilin receptor protein 2 0.0075 0.0149 0.0148
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0099 0.021 0.0209
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.0518 0.0518
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0015 0.006
Trichomonas vaginalis DNA polymerase eta, putative 0.0073 0.0142 0.0136
Echinococcus multilocularis thioredoxin glutathione reductase 0.0236 0.0563 0.0562
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0066 0.0708
Brugia malayi sulfakinin receptor protein 0.023 0.0548 0.0548
Brugia malayi hypothetical protein 0.002 0.0006 0.0005
Brugia malayi polk-prov protein 0.0045 0.007 0.0069
Echinococcus granulosus intermediate filament protein 0.0058 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0061 0.0112 0.0112
Echinococcus granulosus dna polymerase eta 0.0041 0.0059 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0529 0.2003
Trypanosoma cruzi protein farnesyltransferase, putative 0.0401 0.0989 0.3781
Echinococcus granulosus rhodopsin orphan GPCR 0.023 0.0548 0.0548
Echinococcus granulosus death domain containing protein 0.0292 0.0708 0.0708
Echinococcus multilocularis expressed protein 0.0061 0.0112 0.0112
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.012 0.0423
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.002 0.013
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0109 0.0235 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0201 0.0473 0.1787
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.028 0.028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0258 0.0619 0.0842
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0067 0.0057
Onchocerca volvulus 0.023 0.0548 0.2108
Echinococcus multilocularis sodium:hydrogen exchanger 0.0505 0.1258 0.1257
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0099 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0084 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0022 0.001 0.001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0271 0.0654 0.0653
Brugia malayi hypothetical protein 0.0112 0.0244 0.0244
Plasmodium falciparum sodium/hydrogen exchanger, Na+, H+ antiporter 0.0096 0.0203 0.0193
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.016 0.0159
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0066 0.038
Schistosoma mansoni axis inhibition protein axin 0.002 0.0006 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.023 0.0548 0.0548
Mycobacterium ulcerans membrane transporter 0.0096 0.0203 0.2423
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0066 0.0066
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0099 0.021 0.0209
Brugia malayi hypothetical protein 0.002 0.0006 0.0005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.0052 0.0052
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0292 0.0708 0.0708
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0042 0.0124
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0022 0.001 0.0017
Echinococcus multilocularis Ankyrin 0.0295 0.0714 0.0714
Mycobacterium ulcerans hypothetical protein 0.0068 0.013 0.1505
Brugia malayi MAP kinase sur-1 0.0051 0.0086 0.0086
Echinococcus multilocularis lysine specific demethylase 5A 0.0145 0.0328 0.0328
Echinococcus granulosus g-protein coupled receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.1789 0.4569 0.4569
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.001 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0015 0.0018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.023 0.0548 0.0548
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.001 0.0004
Brugia malayi hypothetical protein 0.0028 0.0026 0.0026
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Brugia malayi excitatory GABA receptor EXP-1A 0.0022 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0142 0.0526
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0022 0.001 0.001
Brugia malayi hypothetical protein 0.0205 0.0484 0.0484
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.001 0.0017
Mycobacterium tuberculosis Conserved protein 0.0043 0.0066 0.038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0165 0.0597
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0015 0.006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.006 0.0109 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Echinococcus granulosus peregrin 0.0061 0.0112 0.0111
Echinococcus multilocularis dro:myosuppressin receptor 0.023 0.0548 0.0548
Echinococcus multilocularis rhodopsin orphan GPCR 0.023 0.0548 0.0548
Leishmania major hypothetical protein, conserved 0.0043 0.0066 0.0217
Echinococcus granulosus alpha 1A adrenergic receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0258 0.0619 0.0619
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.002 0.0056
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0063 0.0062
Onchocerca volvulus 0.0043 0.0066 0.0253
Echinococcus granulosus sodium:hydrogen exchanger 7 0.0096 0.0203 0.0202
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0109 0.0235 0.0234
Schistosoma mansoni netrin receptor unc5 0.0292 0.0708 0.0708
Loa Loa (eye worm) G-protein coupled receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Echinococcus granulosus hypothetical protein 0.1722 0.4397 0.4397
Loa Loa (eye worm) sodium-hydrogen exchanger NHE1 0.0096 0.0203 0.0203
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.1026 0.26 0.2599
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0066 0.006
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.049 0.1219 0.1218
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0072 0.0071
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0022 0.001 0.001
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0084 0.0171 0.017
Echinococcus multilocularis cpg binding protein 0.0037 0.0049 0.0048
Onchocerca volvulus 0.0036 0.0046 0.0174
Giardia lamblia Prenyltransferase 0.0401 0.0989 0.098
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0109 0.0235 0.0229
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0052 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Onchocerca volvulus 0.023 0.0548 0.2108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0087 0.0177 0.0167
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0401 0.0989 0.0989
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0049 0.008 0.0471
Entamoeba histolytica sodium/proton antiporter, putative 0.0096 0.0203 0.0197
Entamoeba histolytica sodium/proton antiporter, putative 0.0096 0.0203 0.0197
Echinococcus multilocularis neuropeptide receptor A26 0.0693 0.1741 0.1741
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0067 0.0066
Schistosoma mansoni sodium/hydrogen exchanger 3 (nhe3) 0.0096 0.0203 0.0202
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0073 0.0073
Mycobacterium ulcerans ion antiporter, NhaP 0.0096 0.0203 0.2423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.0052 0.0052
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0109 0.0235 0.0234
Echinococcus granulosus netrin receptor unc 5 0.0292 0.0708 0.0708
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0271 0.0654 0.0653
Echinococcus granulosus FTZ F1 alpha 0.0038 0.0052 0.0052
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus sodium:hydrogen exchanger 0.0505 0.1258 0.1257
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0015 0.002
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0086 0.0295
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0015 0.0032
Plasmodium vivax sodium/hydrogen exchanger 1, putative 0.0096 0.0203 0.0193
Schistosoma mansoni biogenic amine (5HT) receptor 0.023 0.0548 0.0548
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0109 0.0235 0.0319
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.023 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0319 0.0777 0.0777
Onchocerca volvulus 0.0225 0.0535 0.2057
Giardia lamblia NADH oxidase lateral transfer candidate 0.0082 0.0165 0.0155
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0043 0.0066 0.0066
Echinococcus multilocularis neuropeptide receptor 0.023 0.0548 0.0548
Echinococcus granulosus polycomb protein SCMH1 0.0036 0.0046 0.0045
Echinococcus multilocularis expressed protein 0.0391 0.0962 0.0962
Echinococcus multilocularis serotonin receptor 0.023 0.0548 0.0548
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.023 0.0548 0.0548
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0075 0.0149 0.0148
Brugia malayi jmjC domain containing protein 0.0039 0.0054 0.0053
Brugia malayi Probable ClpP-like protease 0.0087 0.0177 0.0177
Loa Loa (eye worm) NHE-3 0.0505 0.1258 0.1258
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0056 0.0177
Schistosoma mansoni jun-related protein 0.0267 0.0642 0.0641
Brugia malayi bZIP transcription factor family protein 0.0061 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.023 0.0548 0.0548
Schistosoma mansoni phosphatidylserine receptor 0.0039 0.0054 0.0053
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.005 0.0044
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.0021 0.0021
Brugia malayi hypothetical protein 0.0197 0.0463 0.0462
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0077 0.026
Echinococcus multilocularis neuropeptide Y receptor 0.023 0.0548 0.0548
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.023 0.0548 0.0548
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0202 0.0476 0.0476
Giardia lamblia Sodium/hydrogen exchanger 3 0.0505 0.1258 0.1249
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0505 0.1258 0.1257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.012 0.0439
Brugia malayi Cation transporter family protein 0.0022 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0015 0.0032
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.1066 0.2705 0.2705
Onchocerca volvulus 0.0058 0.0105 0.0401
Plasmodium falciparum thioredoxin reductase 0.0235 0.0561 0.0552
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0022 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0015 0.0032
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0109 0.0235 0.0234
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0082 0.0165 0.0155
Toxoplasma gondii thioredoxin reductase 0.0235 0.0561 0.0763

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2 nM Inhibition of [3H]- Yohimbine binding against rat kidney cortex Alpha-2B adrenergic receptor ChEMBL. 10602703
Ki (binding) = 3.1 nM Inhibition of [3H]- MK-912 binding against human recombinant Alpha-2A adrenergic receptor ChEMBL. 10602703

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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