Detailed information for compound 312571

Basic information

Technical information
  • TDR Targets ID: 312571
  • Name: 1-(4-methylphenyl)sulfonyl-3-[(4-sulfamoylben zoyl)amino]urea
  • MW: 412.441 | Formula: C15H16N4O6S2
  • H donors: 4 H acceptors: 6 LogP: 0.59 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NS(=O)(=O)c1ccc(cc1)C)NNC(=O)c1ccc(cc1)S(=O)(=O)N
  • InChi: 1S/C15H16N4O6S2/c1-10-2-6-13(7-3-10)27(24,25)19-15(21)18-17-14(20)11-4-8-12(9-5-11)26(16,22)23/h2-9H,1H3,(H,17,20)(H2,16,22,23)(H2,18,19,21)
  • InChiKey: LMEHBRGQNPRHBJ-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-(p-tolylsulfonyl)-3-[(4-sulfamoylbenzoyl)amino]urea
  • 1-[[oxo-(4-sulfamoylphenyl)methyl]amino]-3-(p-tolylsulfonyl)urea
  • 1-(4-methylphenyl)sulfonyl-3-[(4-sulfamoylphenyl)carbonylamino]urea
  • 1-[(4-sulfamoylbenzoyl)amino]-3-tosyl-urea
  • 1-(4-methylphenyl)sulfonyl-3-[[oxo-(4-sulfamoylphenyl)methyl]amino]urea

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) AGC/PKN protein kinase 0.0578 0.2236 0.2236
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0447 0.1614 0.1608
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) hypothetical protein 0.0637 0.2515 0.2515
Echinococcus granulosus tyrosine protein kinase otk 0.0245 0.0654 0.0647
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0214 0.0509 0.0509
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0215 0.0512 0.0512
Loa Loa (eye worm) hypothetical protein 0.0255 0.0702 0.0702
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0123 0.0076 0.0076
Giardia lamblia Kinase, STE STE20 0.0167 0.0284 0.0079
Brugia malayi Myb-like DNA-binding domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Onchocerca volvulus Peroxidasin homolog 0.0113 0.0029 0.0073
Plasmodium falciparum ferrodoxin reductase-like protein 0.0204 0.0459 0.0359
Schistosoma mansoni titin 0.0245 0.0654 0.0654
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1898 0.1898
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Brugia malayi serine/threonine-protein kinase PAK 7 0.0461 0.1681 0.1681
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0277 0.0804 0.2566
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Loa Loa (eye worm) hypothetical protein 0.0245 0.0656 0.0656
Brugia malayi Kinase associated domain 1 family protein 0.0203 0.0458 0.0458
Echinococcus granulosus down syndrome cell adhesion 0.0113 0.0029 0.0021
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Schistosoma mansoni kinase 0.0574 0.2217 0.2217
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Echinococcus granulosus leucine rich repeat containing protein 4 0.0113 0.0029 0.0021
Brugia malayi Stress-activated protein kinase jnk-1 0.0526 0.1986 0.1986
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0165 0.0276 0.0174
Trichomonas vaginalis STE family protein kinase 0.0126 0.0092 0.0293
Onchocerca volvulus Netrin receptor homolog 0.0171 0.0303 0.0905
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Onchocerca volvulus Tyrosine kinase homolog 0.0802 0.3296 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0564 0.2167 0.2167
Entamoeba histolytica cyclin C, putative 0.0431 0.1535 0.6808
Brugia malayi glutamate synthase 0.0204 0.0459 0.0459
Echinococcus granulosus tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Echinococcus granulosus serine:threonine protein kinase N2 0.0578 0.2236 0.223
Leishmania major protein kinase A catalytic subunit isoform 2 0.0224 0.0553 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Entamoeba histolytica protein kinase, putative 0.0183 0.0362 0.158
Echinococcus multilocularis rho associated protein kinase 0.0647 0.2562 0.2557
Echinococcus granulosus fibropellin Ia 0.0224 0.0554 0.0547
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0164 0.027 0.0168
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0233 0.0599 0.2635
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Plasmodium vivax glycogen synthase kinase 3, putative 0.0255 0.0701 0.0463
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0199 0.0438 0.0438
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0665 0.2647 0.2647
Entamoeba histolytica protein kinase, putative 0.0275 0.0799 0.3527
Trichomonas vaginalis glutathione reductase, putative 0.0768 0.3134 1
Brugia malayi Furin-like cysteine rich region family protein 0.0697 0.2798 0.2798
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Plasmodium falciparum calcium-dependent protein kinase 5 0.0199 0.0438 0.0337
Echinococcus multilocularis ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Brugia malayi Protein kinase domain containing protein 0.073 0.2956 0.2956
Echinococcus granulosus epidermal growth factor receptor 0.0485 0.1795 0.1789
Plasmodium falciparum protein kinase 5 0.0235 0.0608 0.0509
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0214 0.0509 0.0509
Echinococcus granulosus serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0164 0.027 0.027
Onchocerca volvulus 0.0413 0.1453 0.4401
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0233 0.0599 0.2635
Onchocerca volvulus 0.0384 0.1313 0.3977
Onchocerca volvulus 0.0413 0.1453 0.4401
Leishmania major casein kinase II, putative 0.0198 0.0431 0.033
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Echinococcus granulosus notch 0.0224 0.0554 0.0547
Brugia malayi putative serine/threonine kinase SADA gamma 0.0154 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0579 0.2239 0.2239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0199 0.0438 0.0438
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.0305 0.0938 0.0938
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0113 0.0029 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0477 0.1754 0.1754
Echinococcus multilocularis 0.0113 0.0029 0.0021
Giardia lamblia Kinase, CMGC CK2 0.0198 0.0431 0.0589
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Brugia malayi cyclin-dependent kinase 9 0.0109 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Echinococcus multilocularis protein kinase c iota type 0.0568 0.2189 0.2184
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0255 0.0701 0.0701
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Giardia lamblia NADH oxidase lateral transfer candidate 0.0768 0.3134 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0485 0.1795 0.1789
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Onchocerca volvulus 0.0113 0.0029 0.0073
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0305 0.0938 0.0938
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi SH2 domain containing protein 0.0131 0.0116 0.0116
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0224 0.0553 0.0454
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Schistosoma mansoni cell adhesion molecule 0.0597 0.2325 0.2325
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0311 0.0966 0.0871
Toxoplasma gondii CMGC kinase, CK2 family 0.0198 0.0431 0.033
Treponema pallidum NADH oxidase 0.0768 0.3134 1
Echinococcus granulosus neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Echinococcus multilocularis peroxidasin 0.0245 0.0656 0.0649
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0702
Plasmodium falciparum thioredoxin reductase 0.2215 1 1
Schistosoma mansoni tyrosine kinase 0.0348 0.1144 0.1144
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Echinococcus granulosus tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.1037 0.1037
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Giardia lamblia Kinase, STE STE20 0.017 0.0297 0.0124
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Brugia malayi Protein kinase domain containing protein 0.0305 0.0941 0.0941
Echinococcus multilocularis expressed conserved protein 0.0167 0.0284 0.0277
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Echinococcus granulosus netrin receptor unc 5 0.0189 0.0391 0.0384
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.015 0.0204 0.0204
Brugia malayi phosphoinositide-dependent protein kinase I 0.0161 0.0254 0.0254
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Trypanosoma brucei hypothetical protein, conserved 0.0204 0.0459 0.0359
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0799 0.0799
Onchocerca volvulus 0.0224 0.0554 0.167
Brugia malayi basement membrane proteoglycan precursor 0.0132 0.0117 0.0117
Trypanosoma brucei carbonic anhydrase-like protein 0.0214 0.0509 0.041
Schistosoma mansoni cell polarity protein 0.0224 0.0554 0.0554
Echinococcus granulosus insulin receptor 0.0602 0.2349 0.2343
Brugia malayi Fes/CIP4 homology domain containing protein 0.0204 0.0462 0.0462
Schistosoma mansoni vav2 0.0165 0.0275 0.0275
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Echinococcus granulosus hypothetical protein 0.0241 0.0636 0.0629
Schistosoma mansoni myosin-binding protein-related 0.0131 0.0115 0.0115
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0538 0.2043 0.2043
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Echinococcus multilocularis casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Trichomonas vaginalis CAMK family protein kinase 0.0431 0.1538 0.4907
Echinococcus multilocularis carbonic anhydrase II 0.0214 0.0509 0.0502
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0131 0.0116 0.0483
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0198 0.0431 0.0186
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Schistosoma mansoni netrin receptor unc5 0.0189 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Brugia malayi hypothetical protein 0.0132 0.0117 0.0117
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.1502 0.1502
Echinococcus multilocularis tyrosine protein kinase shark 0.0348 0.1144 0.1138
Echinococcus multilocularis netrin receptor unc 5 0.0189 0.0391 0.0384
Plasmodium falciparum glycogen synthase kinase 3 0.0255 0.0701 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Plasmodium vivax unspecified product 0.0198 0.0431 0.0186
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Schistosoma mansoni neuroglian 0.0263 0.074 0.074
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.1416 0.1416
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Echinococcus granulosus casein kinase i 0.0215 0.0512 0.0505
Onchocerca volvulus 0.0623 0.245 0.7431
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis slit 2 protein 0.0268 0.0765 0.0758
Brugia malayi SRC-1 0.0306 0.0946 0.0946
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Brugia malayi Sushi domain 0.0413 0.1453 0.1453
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trypanosoma brucei SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0255 0.0701 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Brugia malayi serine/threonine kinase 12 0.0233 0.0599 0.0599
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Schistosoma mansoni tyrosine kinase 0.0128 0.0099 0.0099
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0162 0.0261 0.0012
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0768 0.3134 1
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Echinococcus granulosus lachesin 0.0245 0.0654 0.0647
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Entamoeba histolytica protein kinase, putative 0.0199 0.0438 0.1917
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0316 0.099 0.0895
Echinococcus granulosus slit 2 protein 0.0268 0.0765 0.0758
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Entamoeba histolytica protein kinase, putative 0.017 0.0297 0.1291
Loa Loa (eye worm) TK protein kinase 0.0477 0.1754 0.1754
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Brugia malayi serine/threonine-protein kinase 6 0.0233 0.0599 0.0599
Schistosoma mansoni cell adhesion molecule 0.0245 0.0654 0.0654
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.064 0.2821
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Toxoplasma gondii EGF family domain-containing protein 0.0224 0.0554 0.0455
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Brugia malayi Protein kinase domain containing protein 0.0281 0.0827 0.0827
Onchocerca volvulus 0.0131 0.0116 0.0338
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Echinococcus granulosus cyclin 0.0424 0.1506 0.15
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0132 0.0117 0.011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0768 0.3134 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0326 0.1038 0.1038
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Trypanosoma cruzi Protein kinase B 0.0326 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0242 0.064 0.0542
Schistosoma mansoni nephrin 0.0263 0.074 0.074
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Plasmodium vivax thioredoxin reductase, putative 0.2215 1 1
Brugia malayi protein kinase C II. 0.0405 0.1416 0.1416
Trypanosoma brucei protein kinase, putative 0.0173 0.0313 0.0211
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0203 0.0458 0.0458
Echinococcus multilocularis notch 0.0224 0.0554 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0647 0.2562 0.2562
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0151 0.0209 0.0209
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0235 0.0608 0.0608
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.2043 0.2043
Brugia malayi Cyclin, N-terminal domain containing protein 0.0424 0.1506 0.1506
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Schistosoma mansoni serine/threonine protein kinase 0.0578 0.2236 0.2236
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Echinococcus multilocularis NCK adaptor protein 0.0125 0.0086 0.0079
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0245 0.0654 0.0647
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0384 0.1313 0.1313
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0364 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Brugia malayi STE20-like kinase MST 0.0511 0.1915 0.1915
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Brugia malayi Protein kinase domain containing protein 0.0121 0.0068 0.0068
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Brugia malayi P38 map kinase family protein 2 0.0316 0.099 0.099
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) TK protein kinase 0.0309 0.0957 0.0957
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0431 0.1538 0.1538
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.073 0.2956 0.2956
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0252 0.0689 0.0689
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Giardia lamblia Aurora kinase 0.0233 0.0599 0.1174
Echinococcus multilocularis Immunoglobulin subtype 0.0132 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0463 0.1689 0.1683
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0461 0.1681 0.1681
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Brugia malayi Protein kinase domain containing protein 0.0226 0.0563 0.0563
Schistosoma mansoni serine/threonine kinase 0.0319 0.1008 0.1008
Brugia malayi Tyrosine-protein kinase abl-1 0.0188 0.0385 0.0385
Echinococcus multilocularis growth factor receptor bound protein 2 0.0123 0.0076 0.0069
Onchocerca volvulus 0.0131 0.0116 0.0338
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0154 0.0224 0.0122
Brugia malayi Disorganized muscle protein 1 0.0113 0.0029 0.0029
Loa Loa (eye worm) TK protein kinase 0.025 0.0676 0.0676
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0113 0.0029 0.0029
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0326 0.1037 0.1037
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0204 0.0459 0.0459
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0768 0.3134 0.2803
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Echinococcus granulosus tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni protein kinase 0.073 0.2956 0.2956
Onchocerca volvulus Peroxidasin homolog 0.0114 0.0031 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Echinococcus granulosus activin receptor type 0.0129 0.0104 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.0431 0.1887
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Brugia malayi Prion-like- 0.0245 0.0654 0.0654
Echinococcus granulosus tyrosine protein kinase shark 0.0348 0.1144 0.1138
Plasmodium falciparum glutathione reductase 0.0768 0.3134 0.3062
Onchocerca volvulus 0.0195 0.0417 0.1255
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Temporarily assigned gene name protein 59 0.0258 0.0714 0.0714
Brugia malayi Protein kinase domain containing protein 0.0585 0.2269 0.2269
Echinococcus multilocularis aurora kinase A 0.0233 0.0599 0.0592
Loa Loa (eye worm) hypothetical protein 0.0361 0.1203 0.1203
Loa Loa (eye worm) hypothetical protein 0.0597 0.2322 0.2322
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0275 0.0799 0.0799
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Brugia malayi protein-tyrosine kinase 0.025 0.0676 0.0676
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0768 0.3134 0.2958
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Plasmodium falciparum cGMP-dependent protein kinase 0.0167 0.0284 0.0182
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Echinococcus granulosus growth factor receptor bound protein 2 0.0125 0.0086 0.0079
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Echinococcus multilocularis 0.0241 0.0636 0.0629
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Plasmodium falciparum casein kinase 1 0.0215 0.0512 0.0412
Echinococcus multilocularis PAK box P21 Rho binding 0.0126 0.0092 0.0084
Schistosoma mansoni slit 0.0224 0.0557 0.0557
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0447 0.1614 0.1614
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0165 0.0276 0.0276
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Loa Loa (eye worm) Notch2 0.0224 0.0554 0.0554
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0447 0.1614 0.1614
Onchocerca volvulus 0.0125 0.0083 0.024
Loa Loa (eye worm) carbonic anhydrase 3 0.0214 0.0509 0.0509
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0215 0.0512 0.0512
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0452
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Brugia malayi protein kinase C3,putative 0.0313 0.0976 0.0976
Giardia lamblia Kinase, CMGC SRPK 0.0164 0.027 0.0028
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0235 0.0608 0.0509
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0553
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Brugia malayi Protein kinase domain containing protein 0.0164 0.027 0.027
Brugia malayi GCC2 and GCC3 family protein 0.0637 0.2515 0.2515
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Trypanosoma brucei casein kinase I, isoform 2 0.0215 0.0512 0.0412
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0108 0.0005 0.0005
Brugia malayi protein unc-22 0.0195 0.0417 0.0417
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0467 0.1708 0.1702
Giardia lamblia Kinase, CMGC MAPK 0.0165 0.0276 0.0049
Giardia lamblia Kinase, AGC PKA 0.0311 0.0966 0.2453
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Entamoeba histolytica hypothetical protein 0.0242 0.064 0.2821
Echinococcus granulosus cyclin dependent kinase 9 0.0116 0.0045 0.0037
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Echinococcus multilocularis mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0204 0.0459 0.1464
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Echinococcus granulosus tyrosine protein kinase Srms 0.0545 0.208 0.2074
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0195 0.0417 0.0417
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Schistosoma mansoni c4b-binding protein beta chain 0.0413 0.1453 0.1453
Echinococcus multilocularis titin 0.0195 0.0417 0.041
Echinococcus multilocularis serine threonine protein kinase 0.0401 0.1395 0.1389
Plasmodium vivax serine/threonine kinase-1, putative 0.0305 0.0938 0.0706
Loa Loa (eye worm) thioredoxin reductase 0.2215 1 1
Echinococcus granulosus titin 0.0195 0.0417 0.041
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis casein kinase I gamma 0.0424 0.1502 0.1496
Trypanosoma cruzi casein kinase II, putative 0.0198 0.0431 0.0431
Plasmodium falciparum protein serine/threonine kinase-1 0.0305 0.0938 0.0843
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0526 0.1986 0.1986
Loa Loa (eye worm) hypothetical protein 0.0216 0.0518 0.0518
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0601 0.2343 0.2343
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.027 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.1402 0.1402
Brugia malayi Protein kinase domain containing protein 0.0177 0.0333 0.0333
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Brugia malayi probable protein kinase 0.0527 0.1992 0.1992
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Schistosoma mansoni protein kinase 0.0126 0.0092 0.0092
Echinococcus multilocularis 0.0304 0.0933 0.0926
Echinococcus granulosus roundabout 2 0.071 0.2862 0.2856
Echinococcus granulosus insulin growth factor binding 0.0113 0.0029 0.0021
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Leishmania major protein kinase, putative 0.0167 0.0284 0.0182
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Echinococcus multilocularis tyrosine protein kinase Blk 0.025 0.0676 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0689 0.0689
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0109 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0104 0.043
Loa Loa (eye worm) thyroid receptor interactor 0.0204 0.0462 0.0462
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Schistosoma mansoni atypical protein kinase C 0.0581 0.2247 0.2247
Schistosoma mansoni titin 0.0131 0.0115 0.0115
Brugia malayi hypothetical protein 0.0465 0.17 0.17
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0359
Entamoeba histolytica SH2-protein kinase domain containing protein 0.013 0.0109 0.0452
Trypanosoma brucei trypanothione reductase 0.2215 1 1
Echinococcus granulosus protein kinase c epsilon type 0.0405 0.1416 0.141
Schistosoma mansoni ste20-related kinase 0.0407 0.1425 0.1425
Echinococcus granulosus serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.064 0.064
Brugia malayi Peroxidasin 0.0245 0.0656 0.0656
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0132 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0204 0.0459 0.0215
Schistosoma mansoni vesicular amine transporter 0.0447 0.1614 0.1614
Trypanosoma brucei cdc2-related kinase 3 0.0235 0.0608 0.0509
Echinococcus granulosus ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Echinococcus granulosus carbonic anhydrase II 0.0214 0.0509 0.0502
Brugia malayi Doublecortin family protein 0.0299 0.0911 0.0911
Onchocerca volvulus Slit protein homolog 0.0268 0.0765 0.231
Echinococcus multilocularis hypothetical protein 0.0203 0.0458 0.0451
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0893 0.3731 0.3731
Echinococcus multilocularis calcium activated potassium channel 0.0267 0.076 0.0753
Plasmodium falciparum NIMA related kinase 1 0.027 0.0772 0.0675
Onchocerca volvulus 0.0583 0.226 0.6853
Onchocerca volvulus 0.0113 0.0029 0.0073
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0167 0.0284 0.0182
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Brugia malayi Protein kinase domain containing protein 0.0242 0.064 0.064
Echinococcus multilocularis epidermal growth factor receptor 0.0697 0.2798 0.2792
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0235 0.0608 0.0601
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0526 0.1986 0.198
Loa Loa (eye worm) RhoGAP domain-containing protein 0.015 0.0203 0.0203
Schistosoma mansoni laminin gamma-3 chain 0.0224 0.0554 0.0554
Onchocerca volvulus 0.0114 0.0031 0.0081
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Brugia malayi pregnancy-associated plasma protein-A 0.0413 0.1453 0.1453
Onchocerca volvulus Serine\/threonine kinase homolog 0.0538 0.2043 0.6192
Plasmodium falciparum casein kinase 2, alpha subunit 0.0198 0.0431 0.033
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Entamoeba histolytica thioredoxin reductase, putative 0.0204 0.0459 0.2012
Echinococcus granulosus Protein kinase C brain isozyme 0.0485 0.1792 0.1786
Schistosoma mansoni nephrin related 0.0132 0.0117 0.0117
Echinococcus multilocularis c4b binding protein beta chain 0.0413 0.1453 0.1447
Schistosoma mansoni protein kinase 0.0233 0.0599 0.0599
Trypanosoma brucei protein kinase, putative 0.0255 0.0701 0.0604
Brugia malayi Protein kinase domain containing protein 0.0893 0.3731 0.3731
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Entamoeba histolytica serine/threonine protein kinase, putative 0.0538 0.2043 0.907
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0199 0.0438 0.0438
Giardia lamblia Kinase, CMGC CLK 0.0305 0.0938 0.2355
Echinococcus granulosus neuroglian 0.056 0.215 0.2144
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0702 0.2822 0.2822
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Echinococcus granulosus contactin 0.0263 0.074 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.1986 0.1986
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Schistosoma mansoni roundabout 0.0245 0.0654 0.0654
Entamoeba histolytica protein kinase, putative 0.0202 0.045 0.1971
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Schistosoma mansoni tyrosine kinase 0.0404 0.1411 0.1411
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0165 0.0276 0.0276
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0204 0.0459 0.0459
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0168 0.0291 0.0291
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Toxoplasma gondii histone kinase SNF1, putative 0.0154 0.0224 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni hypothetical protein 0.0204 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0226 0.0563 0.0563
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Echinococcus multilocularis c src tyrosine kinase 0.0188 0.0385 0.0378
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0199 0.0438 0.0337
Plasmodium falciparum calcium-dependent protein kinase 2 0.0199 0.0438 0.0337
Loa Loa (eye worm) disorganized muscle protein 1 0.0113 0.0029 0.0029
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3134
Loa Loa (eye worm) programmed cell death 8 0.0204 0.0459 0.0459
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.0168
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0485 0.1792 0.1786
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Schistosoma mansoni disulfide oxidoreductase 0.0204 0.0459 0.0459
Brugia malayi MAP kinase sur-1 0.0165 0.0276 0.0276
Loa Loa (eye worm) TK protein kinase 0.0373 0.1263 0.1263
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Entamoeba histolytica serine/threonine protein kinase, putative 0.0154 0.0224 0.0966
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0224
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Brugia malayi Sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Giardia lamblia Glutamate synthase 0.0204 0.0459 0.0688
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.016 0.025 0.0148
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Echinococcus granulosus c-Jun N-terminal kinases 0.0526 0.1986 0.198
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Loa Loa (eye worm) SRC-1 0.0306 0.0946 0.0946
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0768 0.3134 0.2803
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0199 0.0438 0.0431
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.1805 0.1805
Plasmodium falciparum serine/threonine protein kinase KIN 0.0154 0.0224 0.0122
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0785 0.3216 0.3216
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus twitchin 0.0624 0.2452 0.2447
Brugia malayi Cam kinase protein 1 0.0199 0.0438 0.0438
Echinococcus multilocularis cyclin dependent kinase 19 0.0601 0.2343 0.2338
Echinococcus multilocularis neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Echinococcus granulosus thioredoxin glutathione reductase 0.2215 1 1
Schistosoma mansoni nephrin 0.0578 0.2237 0.2237
Echinococcus granulosus defective proboscis extension response 0.0447 0.1614 0.1608
Loa Loa (eye worm) TK/EPH protein kinase 0.0228 0.0574 0.0574
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) AGC/PKG protein kinase 0.0167 0.0284 0.0284
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus granulosus NDR protein kinase 0.0319 0.1008 0.1001
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0553
Entamoeba histolytica protein kinase, putative 0.013 0.0109 0.0452
Schistosoma mansoni protein kinase 0.0198 0.0431 0.0431
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Loa Loa (eye worm) TK/INSR protein kinase 0.0602 0.2349 0.2349
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0325 0.1034 0.1034
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Onchocerca volvulus 0.0113 0.0029 0.0073
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Onchocerca volvulus 0.0413 0.1453 0.4401
Entamoeba histolytica protein kinase, putative 0.0255 0.0701 0.3092
Echinococcus granulosus cyclin dependent kinase 0.0235 0.0608 0.0601
Brugia malayi Protein kinase domain containing protein 0.0602 0.2349 0.2349
Echinococcus multilocularis epidermal growth factor receptor 0.0485 0.1795 0.1789
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Echinococcus granulosus CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Giardia lamblia Kinase, AGC AKT 0.0232 0.0591 0.1148
Echinococcus granulosus protein kinase c iota type 0.0568 0.2189 0.2184
Loa Loa (eye worm) hypothetical protein 0.0224 0.0553 0.0553
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0263 0.074 0.0734
Entamoeba histolytica protein kinase 2, putative 0.0311 0.0966 0.4272
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0154 0.0224 0.0224
Plasmodium falciparum serine/threonine protein kinase 0.0164 0.027 0.0168
Brugia malayi casein kinase 1, delta 0.0215 0.0512 0.0512
Echinococcus multilocularis serine:threonine protein kinase N2 0.0578 0.2236 0.223
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0459
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0665 0.2647 0.2647
Echinococcus multilocularis raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0247 0.0663 0.0565
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.095 0.4 0.4
Loa Loa (eye worm) cyclin domain-containing protein 0.0424 0.1506 0.1506
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0299 0.0911 0.0911
Loa Loa (eye worm) hypothetical protein 0.0243 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0161 0.0254 0.0254
Toxoplasma gondii selenide, water dikinase 0.0204 0.0459 0.0359
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0768 0.3134 0.3134
Schistosoma mansoni titin 0.0195 0.0417 0.0417
Echinococcus multilocularis casein kinase i 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0204 0.0459 0.0459
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Trichomonas vaginalis AGC family protein kinase 0.0224 0.0553 0.1765
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0305 0.0938 0.0843
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Schistosoma mansoni ephrin receptor 0.0193 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni tyrosine kinase 0.0282 0.083 0.083
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Schistosoma mansoni netrin receptor unc5 0.0132 0.0117 0.0117
Brugia malayi Protein kinase domain containing protein 0.0424 0.1502 0.1502
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0459
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Echinococcus granulosus hemicentin 1 0.0245 0.0654 0.0647
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Echinococcus granulosus tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Plasmodium falciparum tyrosine kinase-like protein, putative 0.016 0.025 0.0148
Loa Loa (eye worm) AGC/NDR protein kinase 0.0319 0.1008 0.1008
Brugia malayi Thioredoxin reductase 0.2215 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0305 0.0938 0.0843
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Schistosoma mansoni hemicentin 0.0131 0.0115 0.0115
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Echinococcus granulosus cyclin dependent kinase 1 0.0235 0.0608 0.0601
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0198 0.0431 0.0431
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0232 0.0591 0.0591
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0204 0.0459 0.0359
Echinococcus multilocularis protein kinase c epsilon type 0.0405 0.1416 0.141
Toxoplasma gondii rhoptry neck protein RON9 0.0413 0.1453 0.1363
Brugia malayi Protein kinase domain containing protein 0.0309 0.0957 0.0957
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0768 0.3134 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0566 0.2179 0.2179
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Schistosoma mansoni septate junction protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0368 0.0368
Brugia malayi kettin 0.0113 0.0029 0.0029
Loa Loa (eye worm) protein kinase domain-containing protein 0.0424 0.1502 0.1502
Brugia malayi hypothetical protein 0.0442 0.1587 0.1587
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Brugia malayi Protein kinase domain containing protein 0.0326 0.1037 0.1037
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0333 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Trichomonas vaginalis CMGC family protein kinase 0.0305 0.0938 0.2992
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Echinococcus multilocularis calcium dependent protein kinase 0.0136 0.0135 0.0128
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0224 0.0553 0.0454
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0165 0.0276 0.0174
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Trypanosoma cruzi aurora B kinase, putative 0.0233 0.0599 0.0599
Plasmodium falciparum calcium-dependent protein kinase 4 0.0199 0.0438 0.0337
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0564 0.2167 0.2167
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0311 0.0966 0.0959
Echinococcus granulosus mitogen activated protein kinase 11 0.0316 0.099 0.0983
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.3216 0.3216
Brugia malayi hypothetical protein 0.0223 0.0551 0.0551
Brugia malayi Protein kinase domain containing protein 0.0161 0.0254 0.0254
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0438 0.1396
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Echinococcus granulosus N chimaerin 0.015 0.0203 0.0196
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0768 0.3134 0.2803
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0306 0.0946 0.0939
Schistosoma mansoni nck2/grb4 0.0123 0.0076 0.0076
Leishmania major protein kinase A catalytic subunit 0.0224 0.0553 0.0454
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0311 0.0966 0.0966
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Onchocerca volvulus 0.0204 0.0459 0.1381
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus Putative cubilin 0.0224 0.0554 0.167
Echinococcus multilocularis cyclin dependent kinase 9 0.0116 0.0045 0.0037
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0383 0.1309 0.1309
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1045 0.3335
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0538 0.2043 0.1959
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0161 0.0254 0.0247
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0245 0.0654 0.0654
Leishmania major casein kinase, putative 0.0215 0.0512 0.0412
Brugia malayi Protein kinase domain containing protein 0.0702 0.2822 0.2822
Leishmania major protein kinase, putative 0.0233 0.0599 0.05
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.1268 0.5506 0.5506
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Loa Loa (eye worm) cyclin C 0.0849 0.3518 0.3518
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0487 0.1805 0.1805
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0263 0.074 0.0734
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Loa Loa (eye worm) gastrulation defective protein 1 0.0537 0.2041 0.2041
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0768 0.3134 1
Echinococcus granulosus C type lectin domian containing protein 0.0413 0.1453 0.1447
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0199 0.0438 0.0337
Echinococcus granulosus Vam6:Vps39 protein 0.0223 0.0551 0.0544
Loa Loa (eye worm) hypothetical protein 0.0241 0.0636 0.0636
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0165 0.0276 0.0174
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0113 0.0029 0.0021
Onchocerca volvulus 0.0131 0.0116 0.0338
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Plasmodium falciparum calcium-dependent protein kinase 3 0.0199 0.0438 0.0337
Echinococcus granulosus serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Echinococcus multilocularis cyclin dependent kinase 5 0.0235 0.0608 0.0601
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Loa Loa (eye worm) AGC/AKT protein kinase 0.0582 0.2251 0.2251
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Plasmodium falciparum thioredoxin reductase 0.0768 0.3134 0.3062
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0123 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Onchocerca volvulus 0.0277 0.0807 0.2438
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) LAD-2 short isoform 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0177 0.0333 0.0997
Onchocerca volvulus 0.0177 0.0333 0.0997
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0369 0.1242 0.3759
Echinococcus multilocularis C type lectin domian containing protein 0.0413 0.1453 0.1447
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1178 0.376
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Toxoplasma gondii NADPH-glutathione reductase 0.0768 0.3134 0.3062
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0145 0.0182 0.0182
Echinococcus granulosus tyrosine protein kinase 0.0309 0.0957 0.095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0768 0.3134 0.3062
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Loa Loa (eye worm) hypothetical protein 0.0171 0.0306 0.0306
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0199 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Brugia malayi Protein kinase domain containing protein 0.0319 0.1008 0.1008
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0224 0.0554 0.167
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0399 0.1384 0.1384
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0245 0.0654 0.1972
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Echinococcus granulosus basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0349 0.1148 0.1148
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Schistosoma mansoni kinase 0.0109 0.0007 0.0007
Onchocerca volvulus 0.0131 0.0116 0.0338
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1879 0.8405 0.8405
Onchocerca volvulus 0.0223 0.0551 0.166
Echinococcus granulosus dual specificity 0.0242 0.064 0.0633
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Entamoeba histolytica protein kinase domain containing protein 0.0402 0.1402 0.6214
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0799
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0316 0.099 0.099
Loa Loa (eye worm) hypothetical protein 0.0163 0.0264 0.0264
Echinococcus granulosus glutamate synthase 0.0204 0.0459 0.0452
Plasmodium vivax serine/threonine protein kinase, putative 0.0164 0.027 0.002
Brugia malayi Protein kinase domain containing protein 0.0399 0.1384 0.1384
Loa Loa (eye worm) hypothetical protein 0.0131 0.0116 0.0116
Brugia malayi Muscle positioning protein 4 0.0224 0.0554 0.0554
Echinococcus granulosus casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Echinococcus granulosus mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0304 0.0933 0.0933
Echinococcus granulosus tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Entamoeba histolytica casein kinase, putative 0.0215 0.0512 0.2247
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.0204 0.0204
Loa Loa (eye worm) animal heme peroxidase 0.0113 0.0029 0.0029
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Leishmania major carbonic anhydrase-like protein 0.0214 0.0509 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Echinococcus multilocularis serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Onchocerca volvulus 0.0215 0.0512 0.1541
Brugia malayi Protein kinase domain containing protein 0.0235 0.0608 0.0608
Entamoeba histolytica protein kinase domain containing protein 0.0275 0.0799 0.3527
Onchocerca volvulus Putative titin 0.0113 0.0029 0.0073
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0768 0.3134 0.3062
Brugia malayi EGF-like domain containing protein 0.0268 0.0765 0.0765
Brugia malayi Cyclin C 0.0849 0.3518 0.3518
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0331 0.0331
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Brugia malayi Immunoglobulin I-set domain containing protein 0.0189 0.0391 0.0391
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Leishmania major protein kinase, putative 0.0199 0.0438 0.0337
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0263 0.074 0.074
Echinococcus granulosus Immunoglobulin subtype 0.0132 0.0117 0.011
Echinococcus granulosus calcium dependent protein kinase 0.0136 0.0135 0.0128
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0275 0.0799 0.0702
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1268 0.5506 0.5506
Echinococcus granulosus tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Plasmodium vivax casein kinase 1, putative 0.0215 0.0512 0.0269
Schistosoma mansoni vam6/vps39 related 0.0223 0.0551 0.0551
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.046 0.1673 0.1673
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0768 0.3134 0.2958
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Echinococcus granulosus Immunoglobulin 0.0447 0.1614 0.1608
Echinococcus multilocularis protein kinase shaggy 0.0255 0.0701 0.0694
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.027 0.0772 0.0536
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus peroxidasin 0.0245 0.0656 0.0649
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0204 0.0459 0.2012
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi Heparan sulfate 0.0132 0.0117 0.0117
Entamoeba histolytica cell division protein kinase 2, putative 0.0235 0.0608 0.2676
Trypanosoma brucei cdc2-related kinase 1 0.0235 0.0608 0.0509
Echinococcus multilocularis roundabout 2 0.071 0.2862 0.2856
Echinococcus granulosus mitogen activated protein kinase 14 0.0316 0.099 0.0983
Echinococcus granulosus nephrin 0.0131 0.0115 0.0108
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0768 0.3134 0.3062
Brugia malayi map kinase activated protein kinase protein 2 0.0785 0.3216 0.3216
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Plasmodium vivax glutathione reductase, putative 0.2215 1 1
Echinococcus multilocularis dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Brugia malayi Protein kinase domain containing protein 0.0385 0.1318 0.1318
Schistosoma mansoni tyrosine kinase 0.0697 0.2798 0.2798
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis cyclin dependent kinase 0.0235 0.0608 0.0601
Loa Loa (eye worm) hypothetical protein 0.0448 0.1616 0.1616
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Echinococcus granulosus protein tyrosine kinase 0.0579 0.224 0.2234
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0432 0.1544 0.1544
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Loa Loa (eye worm) TK/ABL protein kinase 0.0131 0.0116 0.0116
Loa Loa (eye worm) CAMK protein kinase 0.0195 0.0417 0.0417
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Echinococcus multilocularis death associated protein kinase 1 0.0892 0.3723 0.3718
Brugia malayi notch-like transmembrane receptor 0.0224 0.0554 0.0554
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Echinococcus granulosus NCK adaptor protein 0.0123 0.0076 0.0069
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Trypanosoma cruzi trypanothione reductase, putative 0.0768 0.3134 0.3134
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Onchocerca volvulus 0.0647 0.2562 0.7771
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0199 0.0438 0.0193
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Onchocerca volvulus 0.0131 0.0115 0.0337
Echinococcus multilocularis 0.0193 0.0409 0.0402
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0132 0.0117 0.0117
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Echinococcus granulosus rho-associated protein kinase 1 0.0647 0.2562 0.2557
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Echinococcus granulosus delta-like protein 1 0.0224 0.0554 0.0547
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Brugia malayi Protein kinase domain containing protein 0.0383 0.1309 0.1309
Loa Loa (eye worm) hypothetical protein 0.0369 0.1242 0.1242
Schistosoma mansoni rap gtpase-activating protein 0.0223 0.0551 0.0551
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Mycobacterium tuberculosis Probable oxidoreductase 0.0768 0.3134 0.2803
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Loa Loa (eye worm) projectin 0.0131 0.0115 0.0115
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Onchocerca volvulus 0.0224 0.0554 0.167
Giardia lamblia High cysteine protein 0.0224 0.0554 0.1019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0768 0.3134 1
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0255 0.0701 0.0604
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Echinococcus granulosus serine threonine protein kinase nrc 0.0311 0.0966 0.0959
Onchocerca volvulus Serine\/threonine kinase homolog 0.0326 0.1037 0.3136
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Echinococcus multilocularis fat cadherin tumor suppressor 0.0224 0.0554 0.0547
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0768 0.3134 0.3062
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Echinococcus multilocularis dual specificity 0.0242 0.064 0.0633
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0276 0.0276
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Trypanosoma brucei rac serine-threonine kinase, putative 0.0582 0.2251 0.217
Echinococcus granulosus neural cadherin 0.0224 0.0554 0.0547
Trypanosoma brucei NADH dehydrogenase 0.0204 0.0459 0.0359
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Brugia malayi Protein kinase domain containing protein 0.0431 0.1538 0.1538
Onchocerca volvulus Neurogenic locus notch homolog 0.0224 0.0554 0.167
Entamoeba histolytica cell division protein kinase 2, putative 0.0243 0.0645 0.2842
Entamoeba histolytica protein kinase, putative 0.0126 0.0092 0.0376
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Schistosoma mansoni tyrosine kinase 0.031 0.0963 0.0963
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Loa Loa (eye worm) TK/EGFR protein kinase 0.0697 0.2798 0.2798
Brugia malayi ephrin receptor 1 precursor 0.0125 0.0087 0.0087
Schistosoma mansoni serine/threonine kinase 0.0439 0.1575 0.1575
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0167 0.0284 0.0182
Brugia malayi cell division control protein 2 homolog 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Giardia lamblia Kinase, CMGC DYRK 0.0275 0.0799 0.1871
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0402 0.1402 0.1402
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0359
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0311 0.0966 0.0959
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0311
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0417 0.0417
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Echinococcus multilocularis tyrosine protein kinase Srms 0.025 0.0676 0.0669
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0157 0.024 0.024
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0674 0.2689 0.2689
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0563 0.1798
Toxoplasma gondii rhoptry neck protein RON1 0.0413 0.1453 0.1363
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Schistosoma mansoni hypothetical protein 0.0223 0.0551 0.0551
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0167 0.0284 0.1234
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Echinococcus granulosus cyclin dependent kinase 19 0.0601 0.2343 0.2338
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Echinococcus multilocularis tyrosine protein kinase otk 0.0245 0.0654 0.0647
Brugia malayi Protein kinase c protein 2 0.0229 0.0578 0.0578
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0122
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0768 0.3134 0.3062
Schistosoma mansoni serine/threonine protein kinase 0.0601 0.2343 0.2343
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Plasmodium vivax calcium-dependent protein kinase, putative 0.0199 0.0438 0.0193
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0224 0.0553 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Echinococcus granulosus cyclin dependent kinase 5 0.0235 0.0608 0.0601
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.024 0.024
Brugia malayi Serine/threonine-protein kinase SULU 0.0442 0.1587 0.1587
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Brugia malayi intracellular kinase 0.0255 0.0701 0.0701
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0128 0.0099 0.0099
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis down syndrome cell adhesion 0.0113 0.0029 0.0021
Echinococcus multilocularis glutamate synthase 0.0204 0.0459 0.0452
Echinococcus granulosus neuroglian 0.0263 0.074 0.0734
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Trichomonas vaginalis STE family protein kinase 0.0167 0.0284 0.0907
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.2822 0.2822
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Brugia malayi serine/threonine protein kinase 6 0.0233 0.0599 0.0599
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Entamoeba histolytica disulphide oxidoreductase, putative 0.0204 0.0459 0.2012
Brugia malayi Leucine Rich Repeat family protein 0.0114 0.0031 0.0031
Brugia malayi Animal haem peroxidase family protein 0.0113 0.0029 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.012 0.012
Plasmodium vivax ferrodoxin reductase, putative 0.0204 0.0459 0.0215
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0768 0.3134 0.3062
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Entamoeba histolytica protein kinase , putative 0.0233 0.0599 0.2635
Echinococcus granulosus protein kinase shaggy 0.0255 0.0701 0.0694
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0463 0.1689 0.1689
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.146 0.642 0.6417
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0768 0.3134 0.3062
Trypanosoma brucei polo-like protein kinase 0.0538 0.2043 0.1959
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0174
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0553
Echinococcus granulosus protein kinase 0.0304 0.0933 0.0926
Echinococcus granulosus tyrosine kinase 0.0131 0.0116 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Echinococcus granulosus c4b binding protein beta chain 0.0413 0.1453 0.1447
Giardia lamblia Thioredoxin reductase 0.0204 0.0459 0.0688
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0566 0.2179 0.2179
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0276
Echinococcus multilocularis tyrosine protein kinase 0.0309 0.0957 0.095
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.027
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0199 0.0438 0.0193
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Echinococcus multilocularis neuroglian 0.0263 0.074 0.0734
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0242 0.064 0.064
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0214 0.0509 0.0509
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0579 0.2239 0.2233
Trichomonas vaginalis AGC family protein kinase 0.027 0.0772 0.2463
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Brugia malayi RhoGAP domain containing protein 0.015 0.0203 0.0203
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0599 0.0599
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Leishmania major trypanothione reductase 0.2215 1 1
Entamoeba histolytica casein kinase, putative 0.0198 0.0431 0.1887
Schistosoma mansoni protein kinase 0.0304 0.0933 0.0933
Brugia malayi Protein kinase domain containing protein 0.034 0.1106 0.1106
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Giardia lamblia Kinase, PLK 0.0538 0.2043 0.6201
Trichomonas vaginalis mercuric reductase, putative 0.0768 0.3134 1
Brugia malayi Protein kinase domain 0.017 0.0297 0.0297
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0439 0.1577 0.157
Entamoeba histolytica p21-activated kinase 0.0185 0.0369 0.1612
Toxoplasma gondii casein kinase I 0.0215 0.0512 0.0412
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.1008 0.1001
Brugia malayi serine/threonine-protein kinase plk-2 0.0538 0.2043 0.2043
Loa Loa (eye worm) TK/ROR protein kinase 0.0178 0.0338 0.0338
Loa Loa (eye worm) CDC7 protein kinase 0.0177 0.0333 0.0333
Echinococcus multilocularis fibropellin Ia 0.0224 0.0554 0.0547
Leishmania major NADH dehydrogenase, putative 0.0204 0.0459 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Brugia malayi Egg laying defective protein 4 0.0167 0.0284 0.0284
Brugia malayi Temporarily assigned gene name protein 59 0.0223 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Echinococcus granulosus tyrosine protein kinase Lyn 0.037 0.1248 0.1241
Echinococcus granulosus fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Echinococcus multilocularis rac serine:threonine kinase 0.0326 0.1038 0.1031
Echinococcus multilocularis neural cadherin 0.0224 0.0554 0.0547
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0306 0.0946 0.0939
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0199 0.0438 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Loa Loa (eye worm) TK/FER protein kinase 0.044 0.1578 0.1578
Plasmodium falciparum serine/threonine protein kinase, putative 0.0233 0.0599 0.05
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0199 0.0438 0.0337
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0439 0.1577 0.157
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.2012
Trichomonas vaginalis CAMK family protein kinase 0.0545 0.208 0.6637
Entamoeba histolytica casein kinase 1, putative 0.0215 0.0512 0.2247
Echinococcus granulosus aurora kinase A 0.0233 0.0599 0.0592
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0405 0.1416 0.1416
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0311 0.0966 0.0735
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) glutathione reductase 0.2215 1 1
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Schistosoma mansoni protein kinase C mu 0.0432 0.1544 0.1544
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0291 0.093
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Echinococcus granulosus epidermal growth factor receptor 0.0697 0.2798 0.2792
Trypanosoma brucei aurora B kinase 0.0233 0.0599 0.05
Echinococcus granulosus c src tyrosine kinase 0.0188 0.0385 0.0378
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Echinococcus granulosus titin 0.0195 0.0417 0.041
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0164 0.027 0.0168
Echinococcus multilocularis N chimaerin 0.015 0.0203 0.0196
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis expressed protein 0.0164 0.027 0.0262
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Echinococcus multilocularis mitogen activated protein kinase 0.0165 0.0276 0.0268
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0511 0.1915 0.1915
Toxoplasma gondii thioredoxin reductase 0.2215 1 1
Onchocerca volvulus 0.0113 0.0029 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Echinococcus granulosus Glutaredoxin protein 5 0.0247 0.0664 0.0657
Onchocerca volvulus 0.0285 0.0845 0.2555
Schistosoma mansoni tyrosine kinase 0.0579 0.224 0.224
Echinococcus multilocularis thioredoxin glutathione reductase 0.2215 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.0512 0.0512
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Plasmodium vivax apical sushi protein, putative 0.0413 0.1453 0.1234
Schistosoma mansoni g1/s-specific cyclin C 0.0849 0.3518 0.3518
Schistosoma mansoni slit 0.0114 0.0031 0.0031
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0195 0.0417 0.0417
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Schistosoma mansoni adapter molecule crk 0.0123 0.0076 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0465 0.17 0.17
Echinococcus granulosus protein kinase C gamma type 0.0401 0.1395 0.1389
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0204 0.0459 0.0359
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0161 0.0254 0.0247
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Echinococcus granulosus serine/threonine protein kinase 0.0326 0.1038 0.1031
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0275 0.0799 0.0702
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.034 0.1106 0.1106
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Loa Loa (eye worm) TK protein kinase 0.0183 0.0362 0.0362
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis cyclin 0.0424 0.1506 0.15
Echinococcus multilocularis insulin growth factor binding 0.0113 0.0029 0.0021
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0432 0.1544 0.1544
Echinococcus multilocularis Glutaredoxin protein 5 0.0247 0.0664 0.0657
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Loa Loa (eye worm) TK/FAK protein kinase 0.0585 0.2269 0.2269
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Brugia malayi Protein kinase domain containing protein 0.0582 0.2251 0.2251
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0199 0.0438 0.0193
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Echinococcus multilocularis activin receptor type 0.0129 0.0104 0.0096
Brugia malayi casein kinase I 0.0215 0.0512 0.0512
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0233 0.0599 0.0358
Echinococcus multilocularis twitchin 0.0177 0.0331 0.0324
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0224 0.0554 0.0554
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Trypanosoma cruzi trypanothione reductase, putative 0.2215 1 1
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Echinococcus multilocularis protein jagged 2 0.0224 0.0554 0.0547
Entamoeba histolytica protein kinase, putative 0.0566 0.2179 0.968
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Echinococcus granulosus casein kinase I gamma 0.0424 0.1502 0.1496
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Onchocerca volvulus 0.0224 0.0554 0.167
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Schistosoma mansoni serine/threonine protein kinase 0.0399 0.1384 0.1384
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Echinococcus multilocularis tyrosine protein kinase Abl 0.0188 0.0385 0.0378
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Onchocerca volvulus 0.0131 0.0116 0.0338
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0263 0.074 0.074
Echinococcus granulosus insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Onchocerca volvulus 0.0131 0.0116 0.0338
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0242 0.064 0.0542
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0255 0.0701 0.0701
Plasmodium falciparum apical sushi protein 0.0413 0.1453 0.1363
Loa Loa (eye worm) hypothetical protein 0.0921 0.3863 0.3863
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0263 0.074 0.074
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0076 0.0076
Brugia malayi Hr1 repeat family protein 0.0578 0.2236 0.2236
Onchocerca volvulus 0.0151 0.0209 0.0623
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0167 0.0284 0.1234
Echinococcus multilocularis insulin receptor 0.0602 0.2349 0.2343
Entamoeba histolytica protein kinase domain containing protein 0.0233 0.0599 0.2635
Echinococcus multilocularis lachesin 0.0245 0.0654 0.0647
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0327 0.1043 0.1043
Schistosoma mansoni peroxidasin 0.0132 0.012 0.012
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0413 0.1453 0.1453
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Schistosoma mansoni protein kinase 0.0383 0.1309 0.1309
Echinococcus multilocularis serine:threonine protein kinase 38 0.0319 0.1008 0.1001
Loa Loa (eye worm) hypothetical protein 0.0154 0.0224 0.0224
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Brugia malayi Fibronectin type III domain containing protein 0.0465 0.17 0.17
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Loa Loa (eye worm) hypothetical protein 0.0211 0.0495 0.0495
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0442 0.1587 0.1587
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0204 0.0459 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0204 0.0459 0.0359
Echinococcus multilocularis tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0226 0.0563 0.0563
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Onchocerca volvulus 0.0255 0.0701 0.2117
Echinococcus granulosus tyrosine kinase 0.025 0.0676 0.0669
Entamoeba histolytica protein kinase, putative 0.0161 0.0254 0.11
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Echinococcus granulosus raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Plasmodium vivax protein kinase Crk2 0.0235 0.0608 0.0367
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.027 0.0772 0.0675
Loa Loa (eye worm) notch protein 0.0224 0.0554 0.0554
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0198 0.0198
Echinococcus multilocularis serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Echinococcus multilocularis transfer RNA-Phe 0.0131 0.0115 0.0108
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0154 0.0224 0.0224
Plasmodium falciparum calcium-dependent protein kinase 1 0.0199 0.0438 0.0337
Brugia malayi Delta serrate ligand family protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Onchocerca volvulus 0.0224 0.0554 0.167
Echinococcus granulosus dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus tyrosine protein kinase Blk 0.025 0.0676 0.0669
Onchocerca volvulus 0.0128 0.0099 0.0286
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Toxoplasma gondii aurora kinase 0.0233 0.0599 0.05
Trichomonas vaginalis STE family protein kinase 0.027 0.0772 0.2463
Brugia malayi Protein kinase domain containing protein 0.1879 0.8405 0.8405
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Echinococcus granulosus mitogen activated protein kinase 0.0165 0.0276 0.0268
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0402 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.064 0.2526 0.2526
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0188 0.0385 0.0385
Schistosoma mansoni cell adhesion molecule 0.0113 0.0029 0.0029
Leishmania major protein kinase A catalytic subunit isoform 1 0.0224 0.0553 0.0454
Loa Loa (eye worm) hypothetical protein 0.0268 0.0765 0.0765
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0007 0.0007
Giardia lamblia Kinase, AGC PKA 0.0224 0.0553 0.1015
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0204 0.0459 0.2012
Plasmodium falciparum glutathione reductase 0.2215 1 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Schistosoma mansoni nephrin related 0.0113 0.0029 0.0029
Giardia lamblia Kinase, CK1 Casein kinase 0.0215 0.0512 0.0871
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni protein kinase 0.0527 0.1992 0.1992
Echinococcus multilocularis protein tyrosine kinase 0.0579 0.224 0.2234
Onchocerca volvulus 0.0413 0.1453 0.4401
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Echinococcus granulosus low density lipoprotein receptor ldl 0.0132 0.0117 0.011
Brugia malayi C1-like domain containing protein 0.0432 0.1544 0.1544
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0131 0.0115 0.0108
Onchocerca volvulus 0.0224 0.0554 0.167
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0254 0.0254
Brugia malayi Protein kinase domain containing protein 0.0601 0.2343 0.2343
Brugia malayi SH2 domain containing protein 0.044 0.1578 0.1578
Echinococcus granulosus neurogenic locus protein delta 0.0224 0.0554 0.0547
Trichomonas vaginalis apoptosis inducing factor, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Brugia malayi basement membrane proteoglycan 0.0132 0.0117 0.0117
Loa Loa (eye worm) one IG domain family member 0.0113 0.0029 0.0029
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.1464
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Loa Loa (eye worm) hypothetical protein 0.0238 0.0619 0.0619
Echinococcus multilocularis tyrosine kinase 0.0131 0.0116 0.0109
Echinococcus multilocularis myosin iiia 0.0167 0.0284 0.0277
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0252 0.0689 0.0689
Schistosoma mansoni protein kinase 0.0215 0.0512 0.0512
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0233 0.0599 0.2635
Echinococcus granulosus cGMP dependent protein kinase 0.0167 0.0284 0.0277
Giardia lamblia Kinase, CDC7 0.0177 0.0333 0.0248
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.0204 0.0459 0.0459
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Onchocerca volvulus 0.0131 0.0115 0.0337
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0117 0.011
Entamoeba histolytica protein kinase, putative 0.0319 0.1008 0.4459
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi hypothetical protein 0.0131 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Trypanosoma brucei Casein kinase II 0.0198 0.0431 0.033
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0275 0.0799 0.0799
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Loa Loa (eye worm) TK/ALK protein kinase 0.0305 0.0941 0.0941
Entamoeba histolytica hypothetical protein 0.0386 0.1323 0.5866
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Echinococcus granulosus expressed protein 0.0164 0.027 0.0262
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Echinococcus granulosus calcium activated potassium channel 0.0267 0.076 0.0753
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0467 0.1708 0.1702
Brugia malayi Casein kinase II, alpha chain 0.0198 0.0431 0.0431
Toxoplasma gondii AGC kinase 0.0566 0.2179 0.2097
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2215 1 1
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0305 0.0938 0.0843
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0316 0.099 0.0895
Brugia malayi Variant SH3 domain containing protein 0.015 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1587 0.1587
Loa Loa (eye worm) hypothetical protein 0.0123 0.0076 0.0076
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0702 0.2822 0.8561
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0454
Loa Loa (eye worm) casein kinase 0.036 0.12 0.12
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Echinococcus multilocularis neuroglian 0.056 0.215 0.2144
Echinococcus granulosus Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Schistosoma mansoni hypothetical protein 0.0131 0.0115 0.0115
Schistosoma mansoni protein kinase 0.0129 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 5.8 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 5.8 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 9.8 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 9.8 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 700 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455
Ki (binding) = 700 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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