Detailed information for compound 312571

Basic information

Technical information
  • TDR Targets ID: 312571
  • Name: 1-(4-methylphenyl)sulfonyl-3-[(4-sulfamoylben zoyl)amino]urea
  • MW: 412.441 | Formula: C15H16N4O6S2
  • H donors: 4 H acceptors: 6 LogP: 0.59 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NS(=O)(=O)c1ccc(cc1)C)NNC(=O)c1ccc(cc1)S(=O)(=O)N
  • InChi: 1S/C15H16N4O6S2/c1-10-2-6-13(7-3-10)27(24,25)19-15(21)18-17-14(20)11-4-8-12(9-5-11)26(16,22)23/h2-9H,1H3,(H,17,20)(H2,16,22,23)(H2,18,19,21)
  • InChiKey: LMEHBRGQNPRHBJ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 1-(p-tolylsulfonyl)-3-[(4-sulfamoylbenzoyl)amino]urea
  • 1-[[oxo-(4-sulfamoylphenyl)methyl]amino]-3-(p-tolylsulfonyl)urea
  • 1-(4-methylphenyl)sulfonyl-3-[(4-sulfamoylphenyl)carbonylamino]urea
  • 1-[(4-sulfamoylbenzoyl)amino]-3-tosyl-urea
  • 1-(4-methylphenyl)sulfonyl-3-[[oxo-(4-sulfamoylphenyl)methyl]amino]urea

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Brugia malayi RhoGAP domain containing protein 0.015 0.0203 0.0203
Trypanosoma cruzi trypanothione reductase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0132 0.0117 0.011
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Plasmodium falciparum calcium-dependent protein kinase 2 0.0199 0.0438 0.0337
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.027 0.027
Echinococcus multilocularis cyclin dependent kinase 19 0.0601 0.2343 0.2338
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Brugia malayi Fes/CIP4 homology domain containing protein 0.0204 0.0462 0.0462
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Schistosoma mansoni titin 0.0245 0.0654 0.0654
Echinococcus granulosus neuroglian 0.056 0.215 0.2144
Loa Loa (eye worm) hypothetical protein 0.0211 0.0495 0.0495
Brugia malayi Muscle positioning protein 4 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.095 0.4 0.4
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Echinococcus granulosus Immunoglobulin 0.0447 0.1614 0.1608
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Brugia malayi Fibronectin type III domain containing protein 0.0465 0.17 0.17
Echinococcus multilocularis epidermal growth factor receptor 0.0697 0.2798 0.2792
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0204 0.0459 0.2012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Schistosoma mansoni kinase 0.0109 0.0007 0.0007
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0263 0.074 0.0734
Plasmodium falciparum glycogen synthase kinase 3 0.0255 0.0701 0.0604
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Schistosoma mansoni kinase 0.0574 0.2217 0.2217
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0263 0.074 0.074
Brugia malayi Protein kinase domain containing protein 0.0164 0.027 0.027
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0768 0.3134 1
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Giardia lamblia Kinase, PLK 0.0538 0.2043 0.6201
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0214 0.0509 0.0509
Echinococcus multilocularis serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0276
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0245 0.0654 0.1972
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Brugia malayi hypothetical protein 0.0131 0.0116 0.0116
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0601 0.2343 0.2343
Echinococcus multilocularis Immunoglobulin subtype 0.0132 0.0117 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0799 0.0799
Schistosoma mansoni cell adhesion molecule 0.0113 0.0029 0.0029
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.046 0.1673 0.1673
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus peroxidasin 0.0245 0.0656 0.0649
Onchocerca volvulus 0.0413 0.1453 0.4401
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3134
Loa Loa (eye worm) TK protein kinase 0.0183 0.0362 0.0362
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0768 0.3134 1
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0154 0.0224 0.0122
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0226 0.0563 0.0563
Loa Loa (eye worm) CAMK protein kinase 0.0195 0.0417 0.0417
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0275 0.0799 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1898 0.1898
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.2822 0.2822
Entamoeba histolytica protein kinase, putative 0.0566 0.2179 0.968
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0768 0.3134 0.3062
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0438 0.1396
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0768 0.3134 0.2803
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0145 0.0182 0.0182
Loa Loa (eye worm) AGC/NDR protein kinase 0.0319 0.1008 0.1008
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0311 0.0966 0.0959
Echinococcus multilocularis mitogen activated protein kinase 0.0165 0.0276 0.0268
Plasmodium vivax glutathione reductase, putative 0.2215 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Echinococcus granulosus casein kinase I gamma 0.0424 0.1502 0.1496
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0204 0.0459 0.0359
Onchocerca volvulus Tyrosine kinase homolog 0.0802 0.3296 1
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0151 0.0209 0.0209
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0579 0.2239 0.2233
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0327 0.1043 0.1043
Schistosoma mansoni protein kinase 0.0304 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) RhoGAP domain-containing protein 0.015 0.0203 0.0203
Brugia malayi Casein kinase II, alpha chain 0.0198 0.0431 0.0431
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0316 0.099 0.0895
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Onchocerca volvulus 0.0277 0.0807 0.2438
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus leucine rich repeat containing protein 4 0.0113 0.0029 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0199 0.0438 0.0438
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0768 0.3134 0.2803
Echinococcus granulosus calcium dependent protein kinase 0.0136 0.0135 0.0128
Trichomonas vaginalis mercuric reductase, putative 0.0768 0.3134 1
Loa Loa (eye worm) hypothetical protein 0.0255 0.0702 0.0702
Onchocerca volvulus 0.0224 0.0554 0.167
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus NCK adaptor protein 0.0123 0.0076 0.0069
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis dual specificity 0.0242 0.064 0.0633
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0538 0.2043 0.1959
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Plasmodium falciparum calcium-dependent protein kinase 5 0.0199 0.0438 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0224 0.0553 0.1765
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Onchocerca volvulus 0.0224 0.0554 0.167
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0007 0.0007
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Brugia malayi STE20-like kinase MST 0.0511 0.1915 0.1915
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0076 0.0076
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Toxoplasma gondii rhoptry neck protein RON9 0.0413 0.1453 0.1363
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.012 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0247 0.0663 0.0565
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Plasmodium falciparum serine/threonine protein kinase KIN 0.0154 0.0224 0.0122
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Brugia malayi glutamate synthase 0.0204 0.0459 0.0459
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0199 0.0438 0.0193
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.1986 0.1986
Echinococcus multilocularis roundabout 2 0.071 0.2862 0.2856
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.0204 0.0459 0.0359
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Loa Loa (eye worm) hypothetical protein 0.0128 0.0099 0.0099
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Brugia malayi Cam kinase protein 1 0.0199 0.0438 0.0438
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0195 0.0417 0.0417
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.1805 0.1805
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0431 0.1538 0.1538
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0459
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0485 0.1795 0.1789
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0553
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0188 0.0385 0.0385
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0198 0.0198
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Brugia malayi Furin-like cysteine rich region family protein 0.0697 0.2798 0.2798
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.027 0.0772 0.0536
Echinococcus granulosus carbonic anhydrase II 0.0214 0.0509 0.0502
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0199 0.0438 0.0337
Schistosoma mansoni hypothetical protein 0.0131 0.0115 0.0115
Echinococcus granulosus dual specificity 0.0242 0.064 0.0633
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Echinococcus multilocularis fibropellin Ia 0.0224 0.0554 0.0547
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0359
Brugia malayi Sushi domain 0.0413 0.1453 0.1453
Entamoeba histolytica disulphide oxidoreductase, putative 0.0204 0.0459 0.2012
Plasmodium falciparum protein serine/threonine kinase-1 0.0305 0.0938 0.0843
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0199 0.0438 0.0193
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0167 0.0284 0.0182
Onchocerca volvulus 0.0113 0.0029 0.0073
Entamoeba histolytica protein kinase , putative 0.0233 0.0599 0.2635
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Brugia malayi Stress-activated protein kinase jnk-1 0.0526 0.1986 0.1986
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0168 0.0291 0.0291
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.1464
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Echinococcus granulosus tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Echinococcus granulosus protein kinase c epsilon type 0.0405 0.1416 0.141
Schistosoma mansoni disulfide oxidoreductase 0.0204 0.0459 0.0459
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.0204 0.0204
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Schistosoma mansoni tyrosine kinase 0.0697 0.2798 0.2798
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Brugia malayi protein kinase C II. 0.0405 0.1416 0.1416
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0204 0.0459 0.0459
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Entamoeba histolytica protein kinase, putative 0.0126 0.0092 0.0376
Giardia lamblia Glutamate synthase 0.0204 0.0459 0.0688
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.024 0.024
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Onchocerca volvulus Serine\/threonine kinase homolog 0.0538 0.2043 0.6192
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.027 0.0772 0.0675
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Brugia malayi probable protein kinase 0.0527 0.1992 0.1992
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0597 0.2322 0.2322
Mycobacterium tuberculosis Probable oxidoreductase 0.0768 0.3134 0.2803
Onchocerca volvulus 0.0413 0.1453 0.4401
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0674 0.2689 0.2689
Brugia malayi P38 map kinase family protein 2 0.0316 0.099 0.099
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0316 0.099 0.0895
Treponema pallidum NADH oxidase 0.0768 0.3134 1
Schistosoma mansoni protein kinase 0.0527 0.1992 0.1992
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0768 0.3134 1
Loa Loa (eye worm) thioredoxin reductase 0.2215 1 1
Schistosoma mansoni titin 0.0195 0.0417 0.0417
Onchocerca volvulus 0.0131 0.0116 0.0338
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Plasmodium falciparum calcium-dependent protein kinase 4 0.0199 0.0438 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0545 0.208 0.6637
Entamoeba histolytica protein kinase, putative 0.0199 0.0438 0.1917
Trypanosoma cruzi Protein kinase B 0.0326 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0195 0.0417 0.0417
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0204 0.0459 0.1464
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus granulosus serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Schistosoma mansoni neuroglian 0.0263 0.074 0.074
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.073 0.2956 0.2956
Brugia malayi protein unc-22 0.0195 0.0417 0.0417
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0122
Onchocerca volvulus 0.0255 0.0701 0.2117
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.034 0.1106 0.1106
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Echinococcus granulosus aurora kinase A 0.0233 0.0599 0.0592
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Schistosoma mansoni septate junction protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Plasmodium falciparum protein kinase 5 0.0235 0.0608 0.0509
Onchocerca volvulus 0.0131 0.0116 0.0338
Entamoeba histolytica casein kinase, putative 0.0198 0.0431 0.1887
Brugia malayi Protein kinase domain containing protein 0.0319 0.1008 0.1008
Brugia malayi pregnancy-associated plasma protein-A 0.0413 0.1453 0.1453
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Echinococcus granulosus insulin growth factor binding 0.0113 0.0029 0.0021
Brugia malayi serine/threonine kinase 12 0.0233 0.0599 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Loa Loa (eye worm) hypothetical protein 0.0361 0.1203 0.1203
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus c src tyrosine kinase 0.0188 0.0385 0.0378
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0413 0.1453 0.1453
Loa Loa (eye worm) notch protein 0.0224 0.0554 0.0554
Schistosoma mansoni cell adhesion molecule 0.0597 0.2325 0.2325
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1587 0.1587
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0157 0.024 0.024
Echinococcus granulosus glutamate synthase 0.0204 0.0459 0.0452
Echinococcus granulosus tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Brugia malayi Protein kinase domain containing protein 0.0893 0.3731 0.3731
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0204 0.0459 0.0359
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Onchocerca volvulus 0.0623 0.245 0.7431
Brugia malayi Protein kinase domain containing protein 0.1879 0.8405 0.8405
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.0305 0.0941 0.0941
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0432 0.1544 0.1544
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0131 0.0115 0.0108
Echinococcus multilocularis neuroglian 0.0263 0.074 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.3216 0.3216
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0224 0.0553 0.0454
Loa Loa (eye worm) hypothetical protein 0.0579 0.2239 0.2239
Brugia malayi Serine/threonine-protein kinase SULU 0.0442 0.1587 0.1587
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.0309 0.0957 0.0957
Brugia malayi Protein kinase domain containing protein 0.0281 0.0827 0.0827
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0086 0.0086
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0113 0.0029 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Toxoplasma gondii selenide, water dikinase 0.0204 0.0459 0.0359
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0113 0.0029 0.0021
Onchocerca volvulus 0.0114 0.0031 0.0081
Echinococcus multilocularis protein tyrosine kinase 0.0579 0.224 0.2234
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0161 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0224 0.0554 0.0554
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0461 0.1681 0.1681
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Echinococcus granulosus raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0215 0.0512 0.0512
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Trypanosoma cruzi aurora B kinase, putative 0.0233 0.0599 0.0599
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Echinococcus granulosus neural cadherin 0.0224 0.0554 0.0547
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0311
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0162 0.0261 0.0012
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Giardia lamblia Aurora kinase 0.0233 0.0599 0.1174
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Echinococcus granulosus tyrosine kinase 0.0131 0.0116 0.0109
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0305 0.0938 0.0938
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0214 0.0509 0.0509
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0305 0.0938 0.0843
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Echinococcus granulosus Immunoglobulin subtype 0.0132 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus tyrosine protein kinase otk 0.0245 0.0654 0.0647
Entamoeba histolytica SH2-protein kinase domain containing protein 0.013 0.0109 0.0452
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Echinococcus granulosus activin receptor type 0.0129 0.0104 0.0096
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Onchocerca volvulus 0.0125 0.0083 0.024
Leishmania major protein kinase, putative 0.0167 0.0284 0.0182
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Brugia malayi serine/threonine-protein kinase PAK 7 0.0461 0.1681 0.1681
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.1402 0.1402
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Echinococcus multilocularis tyrosine protein kinase Srms 0.025 0.0676 0.0669
Brugia malayi Hr1 repeat family protein 0.0578 0.2236 0.2236
Toxoplasma gondii thioredoxin reductase 0.2215 1 1
Echinococcus granulosus NDR protein kinase 0.0319 0.1008 0.1001
Echinococcus multilocularis lachesin 0.0245 0.0654 0.0647
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Entamoeba histolytica serine/threonine protein kinase, putative 0.0154 0.0224 0.0966
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi hypothetical protein 0.0223 0.0551 0.0551
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0768 0.3134 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0424 0.1502 0.1502
Brugia malayi Protein kinase domain containing protein 0.0383 0.1309 0.1309
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Echinococcus multilocularis tyrosine protein kinase 0.0309 0.0957 0.095
Loa Loa (eye worm) one IG domain family member 0.0113 0.0029 0.0029
Brugia malayi Prion-like- 0.0245 0.0654 0.0654
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Echinococcus multilocularis serine:threonine protein kinase 38 0.0319 0.1008 0.1001
Echinococcus granulosus lachesin 0.0245 0.0654 0.0647
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Brugia malayi serine/threonine-protein kinase 6 0.0233 0.0599 0.0599
Echinococcus multilocularis PAK box P21 Rho binding 0.0126 0.0092 0.0084
Echinococcus granulosus cyclin dependent kinase 9 0.0116 0.0045 0.0037
Giardia lamblia Kinase, CMGC CK2 0.0198 0.0431 0.0589
Giardia lamblia Kinase, CDC7 0.0177 0.0333 0.0248
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0768 0.3134 0.3062
Brugia malayi Protein kinase domain 0.017 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Loa Loa (eye worm) hypothetical protein 0.0203 0.0458 0.0458
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Schistosoma mansoni hypothetical protein 0.0223 0.0551 0.0551
Echinococcus multilocularis neuroglian 0.056 0.215 0.2144
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0349 0.1148 0.1148
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0306 0.0946 0.0939
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Brugia malayi SH2 domain containing protein 0.0131 0.0116 0.0116
Echinococcus granulosus protein kinase c iota type 0.0568 0.2189 0.2184
Giardia lamblia Kinase, CK1 Casein kinase 0.0215 0.0512 0.0871
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0442 0.1587 0.1587
Echinococcus multilocularis 0.0113 0.0029 0.0021
Echinococcus granulosus dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Brugia malayi Protein kinase domain containing protein 0.0161 0.0254 0.0254
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0463 0.1689 0.1683
Brugia malayi basement membrane proteoglycan 0.0132 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0232 0.0591 0.0591
Brugia malayi map kinase activated protein kinase protein 2 0.0785 0.3216 0.3216
Brugia malayi basement membrane proteoglycan precursor 0.0132 0.0117 0.0117
Plasmodium falciparum tyrosine kinase-like protein, putative 0.016 0.025 0.0148
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Schistosoma mansoni atypical protein kinase C 0.0581 0.2247 0.2247
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0165 0.0276 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Brugia malayi Protein kinase domain containing protein 0.0177 0.0333 0.0333
Loa Loa (eye worm) cyclin domain-containing protein 0.0424 0.1506 0.1506
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Echinococcus multilocularis carbonic anhydrase II 0.0214 0.0509 0.0502
Echinococcus granulosus protein kinase 0.0304 0.0933 0.0926
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0447 0.1614 0.1614
Loa Loa (eye worm) hypothetical protein 0.0123 0.0076 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Onchocerca volvulus Serine\/threonine kinase homolog 0.0326 0.1037 0.3136
Echinococcus multilocularis growth factor receptor bound protein 2 0.0123 0.0076 0.0069
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Loa Loa (eye worm) TK/FAK protein kinase 0.0585 0.2269 0.2269
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0233 0.0599 0.2635
Echinococcus granulosus N chimaerin 0.015 0.0203 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.1416 0.1416
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Plasmodium falciparum glutathione reductase 0.2215 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Echinococcus multilocularis tyrosine kinase 0.0131 0.0116 0.0109
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0485 0.1792 0.1786
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Echinococcus multilocularis twitchin 0.0177 0.0331 0.0324
Plasmodium vivax protein kinase Crk2 0.0235 0.0608 0.0367
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Echinococcus multilocularis ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0123 0.0076 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0477 0.1754 0.1754
Echinococcus multilocularis casein kinase i 0.0215 0.0512 0.0505
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Trypanosoma brucei carbonic anhydrase-like protein 0.0214 0.0509 0.041
Echinococcus multilocularis tyrosine protein kinase otk 0.0245 0.0654 0.0647
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0275 0.0799 0.0702
Echinococcus granulosus cyclin dependent kinase 1 0.0235 0.0608 0.0601
Echinococcus granulosus tyrosine kinase 0.025 0.0676 0.0669
Echinococcus multilocularis cyclin dependent kinase 5 0.0235 0.0608 0.0601
Loa Loa (eye worm) hypothetical protein 0.0204 0.0459 0.0459
Trypanosoma brucei SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Loa Loa (eye worm) TK/FER protein kinase 0.044 0.1578 0.1578
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Giardia lamblia NADH oxidase lateral transfer candidate 0.0768 0.3134 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0768 0.3134 0.2803
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0768 0.3134 0.3134
Schistosoma mansoni protein kinase 0.0198 0.0431 0.0431
Echinococcus granulosus serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0326 0.1037 0.1037
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Giardia lamblia Kinase, CMGC MAPK 0.0165 0.0276 0.0049
Toxoplasma gondii casein kinase I 0.0215 0.0512 0.0412
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0768 0.3134 0.2958
Schistosoma mansoni serine/threonine protein kinase 0.0399 0.1384 0.1384
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0431 0.1538 0.4907
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0263 0.074 0.074
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0439 0.1577 0.157
Brugia malayi Protein kinase domain containing protein 0.0385 0.1318 0.1318
Brugia malayi Protein kinase domain containing protein 0.0602 0.2349 0.2349
Entamoeba histolytica cell division protein kinase 2, putative 0.0235 0.0608 0.2676
Schistosoma mansoni serine/threonine protein kinase 0.0601 0.2343 0.2343
Echinococcus granulosus Protein kinase C brain isozyme 0.0485 0.1792 0.1786
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0204 0.0459 0.0459
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0204 0.0459 0.0215
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Echinococcus multilocularis thioredoxin glutathione reductase 0.2215 1 1
Schistosoma mansoni g1/s-specific cyclin C 0.0849 0.3518 0.3518
Giardia lamblia Kinase, CMGC CLK 0.0305 0.0938 0.2355
Schistosoma mansoni serine/threonine protein kinase 0.0578 0.2236 0.2236
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0702 0.2822 0.2822
Loa Loa (eye worm) TK protein kinase 0.0477 0.1754 0.1754
Loa Loa (eye worm) projectin 0.0131 0.0115 0.0115
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Onchocerca volvulus 0.0224 0.0554 0.167
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Schistosoma mansoni slit 0.0224 0.0557 0.0557
Echinococcus granulosus protein tyrosine kinase 0.0579 0.224 0.2234
Onchocerca volvulus Netrin receptor homolog 0.0171 0.0303 0.0905
Echinococcus multilocularis tyrosine protein kinase Blk 0.025 0.0676 0.0669
Echinococcus granulosus expressed protein 0.0164 0.027 0.0262
Schistosoma mansoni nck2/grb4 0.0123 0.0076 0.0076
Trichomonas vaginalis STE family protein kinase 0.027 0.0772 0.2463
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Entamoeba histolytica casein kinase 1, putative 0.0215 0.0512 0.2247
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Brugia malayi SRC-1 0.0306 0.0946 0.0946
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0275 0.0799 0.0799
Entamoeba histolytica protein kinase, putative 0.0275 0.0799 0.3527
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Brugia malayi Kinase associated domain 1 family protein 0.0203 0.0458 0.0458
Echinococcus granulosus fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Echinococcus granulosus titin 0.0195 0.0417 0.041
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0242 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni c4b-binding protein beta chain 0.0413 0.1453 0.1453
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0439 0.1577 0.157
Brugia malayi SH2 domain containing protein 0.044 0.1578 0.1578
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Schistosoma mansoni protein kinase 0.0233 0.0599 0.0599
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Brugia malayi Temporarily assigned gene name protein 59 0.0223 0.0551 0.0551
Schistosoma mansoni peroxidasin 0.0132 0.012 0.012
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Brugia malayi Protein kinase domain containing protein 0.0601 0.2343 0.2343
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0306 0.0946 0.0939
Onchocerca volvulus 0.0131 0.0116 0.0338
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0199 0.0438 0.0438
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Brugia malayi Protein kinase domain containing protein 0.0585 0.2269 0.2269
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0224 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0163 0.0264 0.0264
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0165 0.0276 0.0174
Toxoplasma gondii aurora kinase 0.0233 0.0599 0.05
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) gastrulation defective protein 1 0.0537 0.2041 0.2041
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Leishmania major NADH dehydrogenase, putative 0.0204 0.0459 0.0359
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0311 0.0966 0.0735
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0299 0.0911 0.0911
Entamoeba histolytica protein kinase, putative 0.0319 0.1008 0.4459
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1178 0.376
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Onchocerca volvulus Slit protein homolog 0.0268 0.0765 0.231
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Loa Loa (eye worm) hypothetical protein 0.0131 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase N2 0.0578 0.2236 0.223
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) AGC/AKT protein kinase 0.0582 0.2251 0.2251
Echinococcus granulosus neurogenic locus protein delta 0.0224 0.0554 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0405 0.1416 0.1416
Loa Loa (eye worm) TK protein kinase 0.0373 0.1263 0.1263
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Brugia malayi Variant SH3 domain containing protein 0.015 0.0203 0.0203
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Echinococcus multilocularis raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Echinococcus multilocularis down syndrome cell adhesion 0.0113 0.0029 0.0021
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Echinococcus multilocularis rho associated protein kinase 0.0647 0.2562 0.2557
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0255 0.0701 0.0701
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0768 0.3134 0.3062
Echinococcus granulosus defective proboscis extension response 0.0447 0.1614 0.1608
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.073 0.2956 0.2956
Echinococcus multilocularis insulin growth factor binding 0.0113 0.0029 0.0021
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Entamoeba histolytica thioredoxin reductase, putative 0.0204 0.0459 0.2012
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Echinococcus multilocularis myosin iiia 0.0167 0.0284 0.0277
Echinococcus multilocularis mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Trichomonas vaginalis apoptosis inducing factor, putative 0.0204 0.0459 0.1464
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2215 1 1
Giardia lamblia Kinase, AGC PKA 0.0224 0.0553 0.1015
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0128 0.0099 0.0286
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0199 0.0438 0.0337
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Loa Loa (eye worm) hypothetical protein 0.0199 0.0438 0.0438
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0467 0.1708 0.1702
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Echinococcus granulosus tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni roundabout 0.0245 0.0654 0.0654
Schistosoma mansoni rap gtpase-activating protein 0.0223 0.0551 0.0551
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) AGC/PKN protein kinase 0.0578 0.2236 0.2236
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Echinococcus multilocularis protein kinase shaggy 0.0255 0.0701 0.0694
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0233 0.0599 0.2635
Schistosoma mansoni tyrosine kinase 0.0282 0.083 0.083
Brugia malayi Heparan sulfate 0.0132 0.0117 0.0117
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0304 0.0933 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.064 0.064
Echinococcus granulosus twitchin 0.0624 0.2452 0.2447
Schistosoma mansoni tyrosine kinase 0.0579 0.224 0.224
Loa Loa (eye worm) TK/ALK protein kinase 0.0305 0.0941 0.0941
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Brugia malayi notch-like transmembrane receptor 0.0224 0.0554 0.0554
Entamoeba histolytica serine/threonine protein kinase, putative 0.0538 0.2043 0.907
Echinococcus granulosus slit 2 protein 0.0268 0.0765 0.0758
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Brugia malayi Protein kinase domain containing protein 0.0702 0.2822 0.2822
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0402 0.1402 0.1402
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0131 0.0116 0.0483
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Brugia malayi protein kinase C3,putative 0.0313 0.0976 0.0976
Onchocerca volvulus 0.0224 0.0554 0.167
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Onchocerca volvulus 0.0369 0.1242 0.3759
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Trypanosoma brucei protein kinase, putative 0.0173 0.0313 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0104 0.043
Leishmania major protein kinase A catalytic subunit isoform 1 0.0224 0.0553 0.0454
Schistosoma mansoni nephrin related 0.0113 0.0029 0.0029
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Schistosoma mansoni ste20-related kinase 0.0407 0.1425 0.1425
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0224 0.0554 0.167
Brugia malayi cell division control protein 2 homolog 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Trichomonas vaginalis CMGC family protein kinase 0.0305 0.0938 0.2992
Echinococcus granulosus c4b binding protein beta chain 0.0413 0.1453 0.1447
Onchocerca volvulus Putative cubilin 0.0224 0.0554 0.167
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0399 0.1384 0.1384
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0564 0.2167 0.2167
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0268 0.0765 0.0765
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0215 0.0512 0.0512
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Brugia malayi protein-tyrosine kinase 0.025 0.0676 0.0676
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0263 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus nephrin 0.0131 0.0115 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.1268 0.5506 0.5506
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0154 0.0224 0.0224
Trichomonas vaginalis AGC family protein kinase 0.027 0.0772 0.2463
Loa Loa (eye worm) casein kinase 0.036 0.12 0.12
Loa Loa (eye worm) hypothetical protein 0.0448 0.1616 0.1616
Plasmodium vivax thioredoxin reductase, putative 0.2215 1 1
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0277 0.0804 0.2566
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0702 0.2822 0.8561
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Echinococcus multilocularis 0.0193 0.0409 0.0402
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0132 0.0117 0.011
Plasmodium vivax apical sushi protein, putative 0.0413 0.1453 0.1234
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Plasmodium falciparum NIMA related kinase 1 0.027 0.0772 0.0675
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Onchocerca volvulus 0.0131 0.0115 0.0337
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Echinococcus granulosus Glutaredoxin protein 5 0.0247 0.0664 0.0657
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Echinococcus multilocularis aurora kinase A 0.0233 0.0599 0.0592
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0167 0.0284 0.1234
Plasmodium vivax casein kinase 1, putative 0.0215 0.0512 0.0269
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0333 0.0333
Onchocerca volvulus 0.0413 0.1453 0.4401
Plasmodium vivax glycogen synthase kinase 3, putative 0.0255 0.0701 0.0463
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Trypanosoma brucei NADH dehydrogenase 0.0204 0.0459 0.0359
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Loa Loa (eye worm) hypothetical protein 0.0243 0.0648 0.0648
Brugia malayi Protein kinase domain containing protein 0.0121 0.0068 0.0068
Echinococcus granulosus calcium activated potassium channel 0.0267 0.076 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0233 0.0599 0.2635
Plasmodium falciparum glutathione reductase 0.0768 0.3134 0.3062
Echinococcus granulosus serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Brugia malayi Immunoglobulin I-set domain containing protein 0.0465 0.17 0.17
Brugia malayi Delta serrate ligand family protein 0.0224 0.0554 0.0554
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.146 0.642 0.6417
Leishmania major carbonic anhydrase-like protein 0.0214 0.0509 0.041
Echinococcus multilocularis NCK adaptor protein 0.0125 0.0086 0.0079
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0117 0.011
Trypanosoma brucei rac serine-threonine kinase, putative 0.0582 0.2251 0.217
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Plasmodium falciparum thioredoxin reductase 0.0768 0.3134 0.3062
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0164 0.027 0.0168
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis notch 0.0224 0.0554 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0599 0.0599
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus granulosus serine/threonine protein kinase 0.0326 0.1038 0.1031
Loa Loa (eye worm) hypothetical protein 0.0238 0.0619 0.0619
Loa Loa (eye worm) disorganized muscle protein 1 0.0113 0.0029 0.0029
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0553
Brugia malayi Disorganized muscle protein 1 0.0113 0.0029 0.0029
Echinococcus multilocularis CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Loa Loa (eye worm) thyroid receptor interactor 0.0204 0.0462 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Echinococcus granulosus roundabout 2 0.071 0.2862 0.2856
Loa Loa (eye worm) glutathione reductase 0.2215 1 1
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Schistosoma mansoni laminin gamma-3 chain 0.0224 0.0554 0.0554
Echinococcus multilocularis calcium dependent protein kinase 0.0136 0.0135 0.0128
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0768 0.3134 0.3062
Toxoplasma gondii histone kinase SNF1, putative 0.0154 0.0224 0.0122
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Loa Loa (eye worm) TK/EGFR protein kinase 0.0697 0.2798 0.2798
Schistosoma mansoni netrin receptor unc5 0.0189 0.0391 0.0391
Onchocerca volvulus 0.0285 0.0845 0.2555
Schistosoma mansoni serine/threonine kinase 0.0439 0.1575 0.1575
Giardia lamblia Kinase, AGC PKA 0.0311 0.0966 0.2453
Schistosoma mansoni adapter molecule crk 0.0123 0.0076 0.0076
Brugia malayi putative serine/threonine kinase SADA gamma 0.0154 0.0224 0.0224
Brugia malayi Protein kinase domain containing protein 0.034 0.1106 0.1106
Echinococcus granulosus insulin receptor 0.0602 0.2349 0.2343
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1879 0.8405 0.8405
Leishmania major protein kinase A catalytic subunit isoform 2 0.0224 0.0553 0.0454
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Giardia lamblia Kinase, CMGC DYRK 0.0275 0.0799 0.1871
Plasmodium vivax calcium-dependent protein kinase, putative 0.0199 0.0438 0.0193
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis serine:threonine protein kinase N2 0.0578 0.2236 0.223
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Giardia lamblia Kinase, STE STE20 0.017 0.0297 0.0124
Onchocerca volvulus Putative titin 0.0113 0.0029 0.0073
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Brugia malayi Cyclin, N-terminal domain containing protein 0.0424 0.1506 0.1506
Trypanosoma brucei protein kinase, putative 0.0255 0.0701 0.0604
Echinococcus multilocularis insulin receptor 0.0602 0.2349 0.2343
Loa Loa (eye worm) CDC7 protein kinase 0.0177 0.0333 0.0333
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Brugia malayi casein kinase I 0.0215 0.0512 0.0512
Echinococcus multilocularis tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Echinococcus granulosus delta-like protein 1 0.0224 0.0554 0.0547
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Giardia lamblia Kinase, STE STE20 0.0167 0.0284 0.0079
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0245 0.0654 0.0654
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0252 0.0689 0.0689
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Brugia malayi Egg laying defective protein 4 0.0167 0.0284 0.0284
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Plasmodium vivax unspecified product 0.0198 0.0431 0.0186
Brugia malayi Leucine Rich Repeat family protein 0.0114 0.0031 0.0031
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0216 0.0518 0.0518
Brugia malayi Protein kinase domain containing protein 0.0326 0.1037 0.1037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0311 0.0966 0.0966
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Schistosoma mansoni ephrin receptor 0.0193 0.0408 0.0408
Brugia malayi Tyrosine-protein kinase abl-1 0.0188 0.0385 0.0385
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0538 0.2043 0.2043
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni vav2 0.0165 0.0275 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0204 0.0459 0.0359
Echinococcus multilocularis calcium activated potassium channel 0.0267 0.076 0.0753
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Loa Loa (eye worm) AGC/PKG protein kinase 0.0167 0.0284 0.0284
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Trichomonas vaginalis glutathione reductase, putative 0.0768 0.3134 1
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Brugia malayi Protein kinase domain containing protein 0.0235 0.0608 0.0608
Plasmodium vivax serine/threonine protein kinase, putative 0.0164 0.027 0.002
Brugia malayi Sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Onchocerca volvulus 0.0113 0.0029 0.0073
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0316 0.099 0.099
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Loa Loa (eye worm) hypothetical protein 0.0637 0.2515 0.2515
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0255 0.0701 0.0604
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0768 0.3134 1
Onchocerca volvulus 0.0384 0.1313 0.3977
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Entamoeba histolytica protein kinase, putative 0.013 0.0109 0.0452
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Schistosoma mansoni vam6/vps39 related 0.0223 0.0551 0.0551
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0275 0.0799 0.0702
Onchocerca volvulus 0.0647 0.2562 0.7771
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0768 0.3134 0.3062
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0768 0.3134 0.2958
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus Vam6:Vps39 protein 0.0223 0.0551 0.0544
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0799
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0235 0.0608 0.0509
Echinococcus granulosus protein kinase shaggy 0.0255 0.0701 0.0694
Brugia malayi p70 ribosomal S6 kinase beta 0.0566 0.2179 0.2179
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0459
Trypanosoma brucei aurora B kinase 0.0233 0.0599 0.05
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0154 0.0224 0.0224
Schistosoma mansoni protein kinase 0.0383 0.1309 0.1309
Schistosoma mansoni nephrin related 0.0132 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0689 0.0689
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0305 0.0938 0.0843
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Trichomonas vaginalis STE family protein kinase 0.0126 0.0092 0.0293
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.016 0.025 0.0148
Echinococcus granulosus mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Schistosoma mansoni myosin-binding protein-related 0.0131 0.0115 0.0115
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.027
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0199 0.0438 0.0337
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0454
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0563 0.1798
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0245 0.0654 0.0647
Schistosoma mansoni slit 0.0114 0.0031 0.0031
Trypanosoma brucei trypanothione reductase 0.2215 1 1
Plasmodium falciparum cGMP-dependent protein kinase 0.0167 0.0284 0.0182
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0198 0.0431 0.0186
Echinococcus granulosus Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1045 0.3335
Echinococcus multilocularis protein jagged 2 0.0224 0.0554 0.0547
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0164 0.027 0.0168
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0113 0.0029 0.0029
Schistosoma mansoni titin 0.0131 0.0115 0.0115
Schistosoma mansoni tyrosine kinase 0.0128 0.0099 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Plasmodium falciparum calcium-dependent protein kinase 3 0.0199 0.0438 0.0337
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Leishmania major casein kinase, putative 0.0215 0.0512 0.0412
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Brugia malayi Protein kinase domain containing protein 0.0305 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Echinococcus multilocularis glutamate synthase 0.0204 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.0241 0.0636 0.0636
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Loa Loa (eye worm) carbonic anhydrase 3 0.0214 0.0509 0.0509
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Giardia lamblia Kinase, CMGC SRPK 0.0164 0.027 0.0028
Brugia malayi Protein kinase domain containing protein 0.0399 0.1384 0.1384
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Echinococcus granulosus neuroglian 0.0263 0.074 0.0734
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Echinococcus granulosus serine threonine protein kinase nrc 0.0311 0.0966 0.0959
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Schistosoma mansoni protein kinase 0.0126 0.0092 0.0092
Echinococcus multilocularis dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Echinococcus multilocularis peroxidasin 0.0245 0.0656 0.0649
Loa Loa (eye worm) hypothetical protein 0.0226 0.0563 0.0563
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0123 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Brugia malayi Protein kinase domain containing protein 0.0424 0.1502 0.1502
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0204 0.0459 0.2012
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0108 0.0005 0.0005
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Entamoeba histolytica protein kinase, putative 0.0202 0.045 0.1971
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) TK protein kinase 0.0309 0.0957 0.0957
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus granulosus tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Loa Loa (eye worm) hypothetical protein 0.0384 0.1313 0.1313
Echinococcus granulosus tyrosine protein kinase Lyn 0.037 0.1248 0.1241
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0204 0.0459 0.0688
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0893 0.3731 0.3731
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Loa Loa (eye worm) animal heme peroxidase 0.0113 0.0029 0.0029
Giardia lamblia Thioredoxin reductase 0.0204 0.0459 0.0688
Schistosoma mansoni netrin receptor unc5 0.0132 0.0117 0.0117
Loa Loa (eye worm) SRC-1 0.0306 0.0946 0.0946
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.064 0.2526 0.2526
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.2043 0.2043
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0242 0.064 0.0542
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Entamoeba histolytica cyclin C, putative 0.0431 0.1535 0.6808
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Brugia malayi Temporarily assigned gene name protein 59 0.0258 0.0714 0.0714
Leishmania major trypanothione reductase 0.2215 1 1
Echinococcus multilocularis expressed conserved protein 0.0167 0.0284 0.0277
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis cyclin dependent kinase 0.0235 0.0608 0.0601
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Echinococcus granulosus mitogen activated protein kinase 14 0.0316 0.099 0.0983
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0511 0.1915 0.1915
Trypanosoma brucei cdc2-related kinase 1 0.0235 0.0608 0.0509
Plasmodium falciparum serine/threonine protein kinase 0.0164 0.027 0.0168
Loa Loa (eye worm) TK/ABL protein kinase 0.0131 0.0116 0.0116
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0174
Entamoeba histolytica protein kinase, putative 0.017 0.0297 0.1291
Onchocerca volvulus Neurogenic locus notch homolog 0.0224 0.0554 0.167
Echinococcus multilocularis c src tyrosine kinase 0.0188 0.0385 0.0378
Echinococcus granulosus C type lectin domian containing protein 0.0413 0.1453 0.1447
Leishmania major protein kinase A catalytic subunit 0.0224 0.0553 0.0454
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis protein kinase c iota type 0.0568 0.2189 0.2184
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.0431 0.1887
Entamoeba histolytica protein kinase 2, putative 0.0311 0.0966 0.4272
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Schistosoma mansoni protein kinase 0.073 0.2956 0.2956
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Schistosoma mansoni cell adhesion molecule 0.0245 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) hypothetical protein 0.0245 0.0656 0.0656
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) Notch2 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis activin receptor type 0.0129 0.0104 0.0096
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Brugia malayi Immunoglobulin I-set domain containing protein 0.0189 0.0391 0.0391
Schistosoma mansoni hypothetical protein 0.0204 0.0459 0.0459
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0165 0.0276 0.0276
Loa Loa (eye worm) TK/INSR protein kinase 0.0602 0.2349 0.2349
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0526 0.1986 0.1986
Echinococcus multilocularis neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Trypanosoma brucei casein kinase I, isoform 2 0.0215 0.0512 0.0412
Entamoeba histolytica cell division protein kinase 2, putative 0.0243 0.0645 0.2842
Onchocerca volvulus 0.0215 0.0512 0.1541
Onchocerca volvulus 0.0204 0.0459 0.1381
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.1037 0.1037
Brugia malayi Cyclin C 0.0849 0.3518 0.3518
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Brugia malayi casein kinase 1, delta 0.0215 0.0512 0.0512
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0526 0.1986 0.198
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis fat cadherin tumor suppressor 0.0224 0.0554 0.0547
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Plasmodium falciparum apical sushi protein 0.0413 0.1453 0.1363
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.0512 0.0512
Entamoeba histolytica protein kinase, putative 0.0183 0.0362 0.158
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Echinococcus granulosus cyclin dependent kinase 0.0235 0.0608 0.0601
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0311 0.0966 0.0959
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0291 0.093
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0161 0.0254 0.0247
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0215
Loa Loa (eye worm) programmed cell death 8 0.0204 0.0459 0.0459
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.0168
Schistosoma mansoni tyrosine kinase 0.0364 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Echinococcus granulosus down syndrome cell adhesion 0.0113 0.0029 0.0021
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0204 0.0459 0.0459
Echinococcus granulosus protein kinase C gamma type 0.0401 0.1395 0.1389
Echinococcus granulosus tyrosine protein kinase shark 0.0348 0.1144 0.1138
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Brugia malayi GCC2 and GCC3 family protein 0.0637 0.2515 0.2515
Echinococcus granulosus epidermal growth factor receptor 0.0485 0.1795 0.1789
Echinococcus granulosus ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Echinococcus granulosus cyclin dependent kinase 5 0.0235 0.0608 0.0601
Onchocerca volvulus 0.0413 0.1453 0.4401
Toxoplasma gondii AGC kinase 0.0566 0.2179 0.2097
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Trypanosoma brucei polo-like protein kinase 0.0538 0.2043 0.1959
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0233 0.0599 0.0358
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0165 0.0276 0.0174
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Brugia malayi Animal haem peroxidase family protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0413 0.1453 0.4401
Echinococcus granulosus cGMP dependent protein kinase 0.0167 0.0284 0.0277
Echinococcus granulosus casein kinase i 0.0215 0.0512 0.0505
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0454
Echinococcus multilocularis slit 2 protein 0.0268 0.0765 0.0758
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Schistosoma mansoni protein kinase 0.0215 0.0512 0.0512
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Brugia malayi hypothetical protein 0.0465 0.17 0.17
Brugia malayi Thioredoxin reductase 0.2215 1 1
Schistosoma mansoni cell polarity protein 0.0224 0.0554 0.0554
Echinococcus granulosus cyclin dependent kinase 19 0.0601 0.2343 0.2338
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0276 0.0276
Echinococcus multilocularis expressed protein 0.0164 0.027 0.0262
Brugia malayi Protein kinase domain containing protein 0.0582 0.2251 0.2251
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Giardia lamblia High cysteine protein 0.0224 0.0554 0.1019
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Echinococcus multilocularis Glutaredoxin protein 5 0.0247 0.0664 0.0657
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Echinococcus multilocularis C type lectin domian containing protein 0.0413 0.1453 0.1447
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Trypanosoma cruzi trypanothione reductase, putative 0.2215 1 1
Onchocerca volvulus 0.0413 0.1453 0.4401
Giardia lamblia Kinase, AGC AKT 0.0232 0.0591 0.1148
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Onchocerca volvulus Peroxidasin homolog 0.0113 0.0029 0.0073
Schistosoma mansoni tyrosine kinase 0.0348 0.1144 0.1144
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0768 0.3134 0.3062
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0359
Onchocerca volvulus 0.0224 0.0554 0.167
Brugia malayi MAP kinase sur-1 0.0165 0.0276 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Schistosoma mansoni vesicular amine transporter 0.0447 0.1614 0.1614
Brugia malayi serine/threonine protein kinase 6 0.0233 0.0599 0.0599
Echinococcus multilocularis rac serine:threonine kinase 0.0326 0.1038 0.1031
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Brugia malayi kettin 0.0113 0.0029 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Loa Loa (eye worm) hypothetical protein 0.0463 0.1689 0.1689
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Schistosoma mansoni tyrosine kinase 0.031 0.0963 0.0963
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0487 0.1805 0.1805
Onchocerca volvulus 0.0177 0.0333 0.0997
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0665 0.2647 0.2647
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0665 0.2647 0.2647
Echinococcus multilocularis netrin receptor unc 5 0.0189 0.0391 0.0384
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Entamoeba histolytica casein kinase, putative 0.0215 0.0512 0.2247
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0113 0.0029 0.0021
Echinococcus granulosus cyclin 0.0424 0.1506 0.15
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0167 0.0284 0.0182
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0224 0.0553 0.0454
Echinococcus granulosus tyrosine protein kinase Srms 0.0545 0.208 0.2074
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Leishmania major casein kinase II, putative 0.0198 0.0431 0.033
Plasmodium falciparum calcium-dependent protein kinase 1 0.0199 0.0438 0.0337
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Entamoeba histolytica protein kinase domain containing protein 0.0402 0.1402 0.6214
Echinococcus multilocularis serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0432 0.1544 0.1544
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Trichomonas vaginalis STE family protein kinase 0.0167 0.0284 0.0907
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0447 0.1614 0.1608
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Echinococcus multilocularis cyclin dependent kinase 9 0.0116 0.0045 0.0037
Schistosoma mansoni protein kinase 0.0129 0.0104 0.0104
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0235 0.0608 0.0608
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Loa Loa (eye worm) TK/ROR protein kinase 0.0178 0.0338 0.0338
Onchocerca volvulus 0.0113 0.0029 0.0073
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0452
Brugia malayi Doublecortin family protein 0.0299 0.0911 0.0911
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Echinococcus granulosus tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Plasmodium falciparum casein kinase 2, alpha subunit 0.0198 0.0431 0.033
Echinococcus multilocularis neural cadherin 0.0224 0.0554 0.0547
Echinococcus multilocularis protein kinase c epsilon type 0.0405 0.1416 0.141
Plasmodium falciparum thioredoxin reductase 0.2215 1 1
Echinococcus multilocularis cyclin 0.0424 0.1506 0.15
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0564 0.2167 0.2167
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0254 0.0254
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Echinococcus granulosus hypothetical protein 0.0241 0.0636 0.0629
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Schistosoma mansoni tyrosine kinase 0.0404 0.1411 0.1411
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus multilocularis 0.0304 0.0933 0.0926
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Echinococcus granulosus CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Echinococcus granulosus neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1268 0.5506 0.5506
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.064 0.2821
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus granulosus fibropellin Ia 0.0224 0.0554 0.0547
Plasmodium vivax ferrodoxin reductase, putative 0.0204 0.0459 0.0215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0785 0.3216 0.3216
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0117 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Echinococcus granulosus epidermal growth factor receptor 0.0697 0.2798 0.2792
Echinococcus granulosus insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Echinococcus granulosus notch 0.0224 0.0554 0.0547
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0305 0.0938 0.0843
Brugia malayi ephrin receptor 1 precursor 0.0125 0.0087 0.0087
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Entamoeba histolytica protein kinase, putative 0.0161 0.0254 0.11
Leishmania major protein kinase, putative 0.0199 0.0438 0.0337
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Echinococcus granulosus contactin 0.0263 0.074 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Echinococcus multilocularis 0.0241 0.0636 0.0629
Trypanosoma brucei Casein kinase II 0.0198 0.0431 0.033
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus granulosus tyrosine protein kinase Blk 0.025 0.0676 0.0669
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0199 0.0438 0.0438
Entamoeba histolytica protein kinase domain containing protein 0.0275 0.0799 0.3527
Echinococcus multilocularis tyrosine protein kinase Abl 0.0188 0.0385 0.0378
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Brugia malayi C1-like domain containing protein 0.0432 0.1544 0.1544
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0255 0.0701 0.0604
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0242 0.064 0.2821
Echinococcus multilocularis epidermal growth factor receptor 0.0485 0.1795 0.1789
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Brugia malayi Myb-like DNA-binding domain containing protein 0.0113 0.0029 0.0029
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0402 0.1402 0.1402
Onchocerca volvulus 0.0413 0.1453 0.4401
Echinococcus multilocularis casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0311 0.0966 0.0871
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0417 0.0417
Echinococcus granulosus hemicentin 1 0.0245 0.0654 0.0647
Echinococcus multilocularis serine threonine protein kinase 0.0401 0.1395 0.1389
Echinococcus granulosus mitogen activated protein kinase 11 0.0316 0.099 0.0983
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Loa Loa (eye worm) LAD-2 short isoform 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0131 0.0116 0.0338
Plasmodium falciparum serine/threonine protein kinase, putative 0.0233 0.0599 0.05
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0199 0.0438 0.0193
Loa Loa (eye worm) cyclin C 0.0849 0.3518 0.3518
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0252 0.0689 0.0689
Echinococcus granulosus casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Echinococcus granulosus c-Jun N-terminal kinases 0.0526 0.1986 0.198
Toxoplasma gondii EGF family domain-containing protein 0.0224 0.0554 0.0455
Entamoeba histolytica protein kinase domain containing protein 0.0233 0.0599 0.2635
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.1008 0.1001
Brugia malayi Protein kinase domain containing protein 0.0226 0.0563 0.0563
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.015 0.0204 0.0204
Trypanosoma brucei cdc2-related kinase 3 0.0235 0.0608 0.0509
Entamoeba histolytica p21-activated kinase 0.0185 0.0369 0.1612
Plasmodium vivax serine/threonine kinase-1, putative 0.0305 0.0938 0.0706
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0553
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Schistosoma mansoni serine/threonine kinase 0.0319 0.1008 0.1008
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Echinococcus multilocularis casein kinase I gamma 0.0424 0.1502 0.1496
Brugia malayi hypothetical protein 0.0442 0.1587 0.1587
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0224 0.0554 0.0554
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0263 0.074 0.0734
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0199 0.0438 0.0431
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Echinococcus granulosus rho-associated protein kinase 1 0.0647 0.2562 0.2557
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0467 0.1708 0.1702
Echinococcus multilocularis transfer RNA-Phe 0.0131 0.0115 0.0108
Leishmania major protein kinase, putative 0.0233 0.0599 0.05
Onchocerca volvulus 0.0131 0.0115 0.0337
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Onchocerca volvulus 0.0131 0.0116 0.0338
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0165 0.0276 0.0276
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Brugia malayi serine/threonine-protein kinase plk-2 0.0538 0.2043 0.2043
Loa Loa (eye worm) TK/EPH protein kinase 0.0228 0.0574 0.0574
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0109 0.0007 0.0007
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0368 0.0368
Echinococcus multilocularis titin 0.0195 0.0417 0.041
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0566 0.2179 0.2179
Toxoplasma gondii NADPH-glutathione reductase 0.0768 0.3134 0.3062
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Echinococcus multilocularis N chimaerin 0.015 0.0203 0.0196
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0255 0.0701 0.0701
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Brugia malayi cyclin-dependent kinase 9 0.0109 0.0007 0.0007
Schistosoma mansoni nephrin 0.0263 0.074 0.074
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0383 0.1309 0.1309
Onchocerca volvulus 0.0113 0.0029 0.0073
Brugia malayi EGF-like domain containing protein 0.0268 0.0765 0.0765
Echinococcus multilocularis tyrosine protein kinase shark 0.0348 0.1144 0.1138
Onchocerca volvulus 0.0583 0.226 0.6853
Schistosoma mansoni hemicentin 0.0131 0.0115 0.0115
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0326 0.1038 0.1038
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0164 0.027 0.027
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0214 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0921 0.3863 0.3863
Echinococcus multilocularis c4b binding protein beta chain 0.0413 0.1453 0.1447
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus titin 0.0195 0.0417 0.041
Schistosoma mansoni protein kinase C mu 0.0432 0.1544 0.1544
Plasmodium falciparum casein kinase 1 0.0215 0.0512 0.0412
Echinococcus granulosus thioredoxin glutathione reductase 0.2215 1 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0242 0.064 0.0542
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0199 0.0438 0.0337
Brugia malayi intracellular kinase 0.0255 0.0701 0.0701
Toxoplasma gondii CMGC kinase, CK2 family 0.0198 0.0431 0.033
Echinococcus granulosus netrin receptor unc 5 0.0189 0.0391 0.0384
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0171 0.0306 0.0306
Echinococcus multilocularis death associated protein kinase 1 0.0892 0.3723 0.3718
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0768 0.3134 0.3062
Trypanosoma cruzi casein kinase II, putative 0.0198 0.0431 0.0431
Echinococcus granulosus tyrosine protein kinase 0.0309 0.0957 0.095
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0132 0.0117 0.0117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Brugia malayi Peroxidasin 0.0245 0.0656 0.0656
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Echinococcus granulosus basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Onchocerca volvulus Peroxidasin homolog 0.0114 0.0031 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0331 0.0331
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0224 0.0553 0.0454
Entamoeba histolytica hypothetical protein 0.0386 0.1323 0.5866
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Onchocerca volvulus 0.0223 0.0551 0.166
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Schistosoma mansoni serine/threonine protein kinase 0.0647 0.2562 0.2562
Onchocerca volvulus 0.0151 0.0209 0.0623
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Brugia malayi phosphoinositide-dependent protein kinase I 0.0161 0.0254 0.0254
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0702
Brugia malayi Protein kinase domain containing protein 0.0431 0.1538 0.1538
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Toxoplasma gondii rhoptry neck protein RON1 0.0413 0.1453 0.1363
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0198 0.0431 0.0431
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.2012
Echinococcus granulosus growth factor receptor bound protein 2 0.0125 0.0086 0.0079
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0177 0.0333 0.0997
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0359
Entamoeba histolytica protein kinase, putative 0.0255 0.0701 0.3092
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0325 0.1034 0.1034
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.1502 0.1502
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0447 0.1614 0.1614
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Brugia malayi hypothetical protein 0.0132 0.0117 0.0117
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0224
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Loa Loa (eye worm) hypothetical protein 0.0369 0.1242 0.1242
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Echinococcus granulosus low density lipoprotein receptor ldl 0.0132 0.0117 0.011
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Echinococcus multilocularis hypothetical protein 0.0203 0.0458 0.0451
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Brugia malayi Protein kinase c protein 2 0.0229 0.0578 0.0578
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0235 0.0608 0.0601
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0413 0.1453 0.4401
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0161 0.0254 0.0247
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0154 0.0224 0.0224
Echinococcus granulosus mitogen activated protein kinase 0.0165 0.0276 0.0268
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0131 0.0116 0.0338
Plasmodium falciparum ferrodoxin reductase-like protein 0.0204 0.0459 0.0359
Schistosoma mansoni nephrin 0.0578 0.2237 0.2237
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) TK protein kinase 0.025 0.0676 0.0676
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0167 0.0284 0.1234
Brugia malayi Protein kinase domain containing protein 0.0242 0.064 0.064
Onchocerca volvulus 0.0195 0.0417 0.1255

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 5.8 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 5.8 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 9.8 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 9.8 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 700 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455
Ki (binding) = 700 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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