Detailed information for compound 47154

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 418.652 | Formula: C27H46O3
  • H donors: 1 H acceptors: 3 LogP: 7.87 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCCC(C1CCC2[C@]1(C)CCC1C2[C@@H](C)CC(=O)[C@]1(C)CCC(=O)O)C)C
  • InChi: 1S/C27H46O3/c1-17(2)8-7-9-18(3)20-10-11-21-25-19(4)16-23(28)27(6,15-13-24(29)30)22(25)12-14-26(20,21)5/h17-22,25H,7-16H2,1-6H3,(H,29,30)/t18?,19-,20?,21?,22?,25?,26+,27+/m0/s1
  • InChiKey: GOSURFASCRNOMA-RSLLPWARSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens farnesyltransferase, CAAX box, alpha Starlite/ChEMBL References
Rattus norvegicus Protein farnesyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, beta [EC:2.5.1.58], putative Get druggable targets OG5_128081 All targets in OG5_128081
Neospora caninum hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium knowlesi conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Neospora caninum protein farnesyltranstransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus multilocularis protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus granulosus protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei protein farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax prenyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Theileria parva hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium knowlesi protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium berghei protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Leishmania donovani farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium berghei protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Theileria parva farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Giardia lamblia Prenyltransferase Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania major farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, alpha [EC:2.5.1.58 2.5.1.59], putative Get druggable targets OG5_128459 All targets in OG5_128459
Cryptosporidium parvum farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Giardia lamblia Rab geranylgeranyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium vivax conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma mansoni protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium knowlesi protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Leishmania infantum farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei gambiense protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus multilocularis protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus granulosus protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Babesia bovis prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium hominis chain B, structure of fpt bound to ggpp Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Cryptosporidium hominis farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Babesia bovis protein prenyltransferase alpha subunit repeat domain containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Entamoeba histolytica protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania braziliensis farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma mansoni protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium falciparum protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium falciparum protein farnesyltransferase subunit alpha Get druggable targets OG5_128459 All targets in OG5_128459
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Leishmania mexicana farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium parvum protein geranyl-geranyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium yoelii Prenyltransferase and squalene oxidase repeat, putative Get druggable targets OG5_128081 All targets in OG5_128081
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0013 0.0049
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0041 0.002 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Brugia malayi CXXC zinc finger family protein 0.0205 0.0478 0.1044
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0325 0.0813 0.0811
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0014 0.0051
Loa Loa (eye worm) transcriptional regulator 0.0375 0.0952 0.2092
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0062 0.008 0.0368
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0368 0.2314
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0103 0.0504
Toxoplasma gondii calcium binding egf domain-containing protein 0.0097 0.0176 0.0231
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0596 0.1569 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0124 0.0768
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0062 0.008 0.0368
Trypanosoma brucei cytochrome P450, putative 0.0099 0.0183 0.1127
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.0728 0.7638
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0066 0.0313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.011 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Schistosoma mansoni neurotransmitter gated ion channel 0.0156 0.034 0.0337
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0368 0.2331
Onchocerca volvulus Putative nachr subunit 0.0289 0.0711 0.3572
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Giardia lamblia Rab geranylgeranyltransferase 0.0218 0.0513 0.5355
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Brugia malayi Trypsin family protein 0.0056 0.0061 0.0126
Trypanosoma cruzi cytochrome P450, putative 0.0099 0.0183 0.1146
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Onchocerca volvulus 0.0176 0.0395 0.1977
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0097 0.0176 0.0379
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0438 0.1129 0.1127
Toxoplasma gondii hypothetical protein 0.0143 0.0304 0.0402
Loa Loa (eye worm) hypothetical protein 0.0035 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Loa Loa (eye worm) cysteine protease 0.0035 0.0004 0.0008
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0139 0.0867
Schistosoma mansoni chromatin regulatory protein sir2 0.0375 0.0952 0.0949
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0156 0.034 0.0739
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0139 0.0867
Echinococcus granulosus dnaJ subfamily B 0.2921 0.8058 0.8058
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0062 0.008 0.0368
Giardia lamblia Sirtuin type 2 0.0071 0.0103 0.1009
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0071 0.0103 0.1053
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Giardia lamblia Hypothetical protein 0.0375 0.0952 1
Brugia malayi notch-like transmembrane receptor 0.0037 0.0009 0.0011
Echinococcus granulosus hormone sensitive lipase 0.047 0.1216 0.1214
Schistosoma mansoni hypothetical protein 0.0062 0.008 0.0077
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0176 0.0398 0.0395
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0282 0.0693 0.4402
Echinococcus multilocularis fmrfamide receptor 0.0041 0.002 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0505 0.3204
Schistosoma mansoni neuropeptide receptor 0.0041 0.002 0.0017
Schistosoma mansoni biogenic amine receptor 0.0041 0.002 0.0017
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0041 0.002 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0014 0.0011
Onchocerca volvulus 0.0176 0.0395 0.1977
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0062 0.008 0.0368
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi transcriptional regulator, Sir2 family protein 0.0375 0.0952 0.2086
Echinococcus granulosus mixed lineage leukemia protein mll 0.0054 0.0057 0.0054
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.0398 0.0395
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0156 0.034 0.0739
Brugia malayi Cytochrome P450 family protein 0.0099 0.0183 0.0395
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi Cytochrome P450 family protein 0.0221 0.0522 0.1141
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0368 0.1827
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0799
Echinococcus multilocularis Galectin, carbohydrate recognition domain 0.0121 0.0242 0.0239
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0091 0.0539
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0066 0.0376
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0041 0.002 0.0017
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0289 0.0711 0.0709
Onchocerca volvulus 0.0036 0.0007 0.0017
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0014 0.0051
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Giardia lamblia Hypothetical protein 0.008 0.0129 0.1277
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0055 0.006 0.0132
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0062 0.008 0.0368
Leishmania major glutaminyl cyclase, putative 0.0039 0.0013 0.0063
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0062 0.008 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0325 0.0813 0.1079
Treponema pallidum hypothetical protein 0.0745 0.1986 1
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0075 0.0115 0.0112
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0062 0.008 0.0368
Echinococcus granulosus nAChR subunit 0.0156 0.034 0.0337
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0041 0.002 0.0017
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Echinococcus granulosus G protein coupled receptor 139 0.0041 0.002 0.0017
Echinococcus multilocularis Mastin 0.0056 0.0061 0.0058
Schistosoma mansoni nicalin (M28 family) 0.0039 0.0013 0.0011
Echinococcus granulosus bloom syndrome protein 0.0063 0.0081 0.0078
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0053 0.0315
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0062 0.008 0.0487
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0053 0.0315
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.008 0.0129 0.0275
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0368 0.1842
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.008 0.0129 0.0799
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0097 0.0176 0.0386
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.008 0.0129 0.0126
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0008 0.003
Schistosoma mansoni inositol monophosphatase 0.0078 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0041 0.002 0.0017
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.008 0.0129 0.0126
Echinococcus multilocularis g protein coupled receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0121 0.0242 0.0532
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Toxoplasma gondii PAN domain-containing protein 0.0176 0.0395 0.0523
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2628 0.7242 0.7241
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0071 0.0103 0.0504
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0057
Echinococcus multilocularis neurogenic locus protein delta 0.0037 0.0009 0.0006
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0368 0.2314
Loa Loa (eye worm) hypothetical protein 0.0163 0.036 0.0792
Brugia malayi GCC2 and GCC3 family protein 0.0037 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.015 0.0324 0.338
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0043 0.0041
Echinococcus multilocularis neuropeptide receptor 0.0041 0.002 0.0017
Onchocerca volvulus 0.0075 0.0115 0.0561
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0076 0.0074
Schistosoma mansoni hypothetical protein 0.0042 0.0023 0.002
Brugia malayi hypothetical protein 0.0133 0.0277 0.0602
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi Carboxylesterase family protein 0.0065 0.0088 0.0186
Brugia malayi RE15519p 0.0041 0.002 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0289 0.0711 0.1558
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0115 0.071
Brugia malayi Peptidase family M28 containing protein 0.0039 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0325 0.0813 0.5172
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0041 0.002 0.0017
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0041 0.002 0.0036
Brugia malayi Cation transporter family protein 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0083 0.0138 0.0303
Echinococcus multilocularis neuropeptide receptor A26 0.2453 0.6753 0.6752
Echinococcus granulosus tar DNA binding protein 0.0064 0.0084 0.0081
Leishmania major hypothetical protein, conserved 0.0039 0.0013 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0062 0.008 0.0368
Echinococcus granulosus notch 0.0037 0.0009 0.0006
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Loa Loa (eye worm) ATP-dependent DNA helicase 0.005 0.0046 0.01
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0008 0.0018
Trypanosoma brucei cAMP-specific phosphodiesterase 0.008 0.0129 0.0779
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0013 0.001
Toxoplasma gondii calcium binding egf domain-containing protein 0.0097 0.0176 0.0231
Brugia malayi Pre-SET motif family protein 0.0655 0.1734 0.3808
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0046 0.0035 0.0159
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0003 0.0001
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Trypanosoma cruzi glutaminyl cyclase, putative 0.0039 0.0013 0.0063
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0075 0.0115 0.1173
Brugia malayi Tachykinin-like peptides receptor 99D 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Echinococcus multilocularis peregrin 0.0036 0.0006 0.0003
Schistosoma mansoni chromatin regulatory protein sir2 0.0375 0.0952 0.0949
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0075 0.0115 0.0112
Echinococcus multilocularis ephrin type A receptor 4 A 0.0067 0.0093 0.0091
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0075 0.0115 0.071
Onchocerca volvulus 0.0041 0.002 0.0083
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0062 0.008 0.0368
Loa Loa (eye worm) hypothetical protein 0.0218 0.0513 0.1129
Onchocerca volvulus 0.0039 0.0013 0.0049
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Echinococcus multilocularis acetylcholinesterase 0.0065 0.0088 0.0085
Echinococcus granulosus neural cadherin 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0078 0.0124 0.0272
Brugia malayi sulfakinin receptor protein 0.0041 0.002 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0041 0.002 0.0017
Schistosoma mansoni neurotransmitter gated ion channel 0.0133 0.0277 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus multilocularis neurogenic locus protein delta 0.0037 0.0009 0.0006
Schistosoma mansoni acetylcholine receptor-related 0.0133 0.0277 0.0275
Toxoplasma gondii ABC1 family protein 0.0036 0.0007 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0007 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Onchocerca volvulus 0.0041 0.002 0.0083
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0008 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.022 0.0217
Trichomonas vaginalis set domain proteins, putative 0.0745 0.1985 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0067 0.0093 0.009
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.005 0.0046 0.0058
Schistosoma mansoni biogenic amine receptor 0.0041 0.002 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0091 0.02
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0066 0.0063
Echinococcus multilocularis neuropeptides capa receptor 0.0041 0.002 0.0017
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0192 0.0442 0.2212
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0192 0.0442 0.2212
Brugia malayi nicalin 0.0039 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Giardia lamblia Sgs1 DNA helicase, putative 0.005 0.0046 0.0396
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Loa Loa (eye worm) hypothetical protein 0.0069 0.0099 0.0218
Echinococcus multilocularis geminin 0.1229 0.3335 0.3333
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0289 0.0711 0.1564
Loa Loa (eye worm) hypothetical protein 0.0097 0.0176 0.0386
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0136 0.0291
Schistosoma mansoni hypothetical protein 0.0041 0.002 0.0017
Treponema pallidum fructose-bisphosphate aldolase 0.0295 0.0728 0.3638
Echinococcus granulosus cytochrome P450 2K1 0.0062 0.008 0.0077
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0101 0.0474
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0021 0.0018
Onchocerca volvulus 0.0101 0.0187 0.0928
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0093 0.0197
Brugia malayi hypothetical protein 0.0133 0.0277 0.0602
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0004 0.0008
Echinococcus granulosus carboxylesterase 5A 0.0065 0.0088 0.0085
Toxoplasma gondii hypothetical protein 0.0039 0.0013 0.0015
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0192 0.0442 0.2212
Brugia malayi Muscle positioning protein 4 0.0037 0.0009 0.0011
Brugia malayi mbt repeat family protein 0.0049 0.0043 0.0088
Loa Loa (eye worm) PAN domain-containing protein 0.0176 0.0395 0.0869
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0124 0.0162
Leishmania major cytochrome p450-like protein 0.0062 0.008 0.0487
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0076 0.0074
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0099 0.0183 0.0402
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) PAN domain-containing protein 0.0176 0.0395 0.0869
Schistosoma mansoni microtubule-associated protein tau 0.3617 1 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0133 0.0277 0.0602
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0041 0.002 0.0017
Echinococcus granulosus neuropeptide FF receptor 2 0.0041 0.002 0.0017
Schistosoma mansoni neuropeptide receptor 0.0041 0.002 0.0017
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0062 0.008 0.0368
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.008 0.0129 0.0126
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Brugia malayi leucyl aminopeptidase 0.0039 0.0013 0.0022
Loa Loa (eye worm) PDE1B protein 0.1663 0.4548 1
Schistosoma mansoni galectin 0.0121 0.0242 0.0239
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0124 0.059
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Onchocerca volvulus 0.0056 0.0061 0.0289
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0062 0.008 0.0368
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0218 0.0513 0.0511
Onchocerca volvulus 0.0041 0.002 0.0083
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0307 0.1517
Echinococcus multilocularis protein jagged 1 0.0037 0.0009 0.0006
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Schistosoma mansoni amine GPCR 0.0041 0.002 0.0017
Brugia malayi Delta serrate ligand family protein 0.0037 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Schistosoma mansoni survival motor neuron protein 0.0151 0.0326 0.0323
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0289 0.0711 0.0709
Echinococcus multilocularis neuropeptide Y receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0218 0.0513 0.2573
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0289 0.0711 0.0709
Schistosoma mansoni DNA polymerase eta 0.0057 0.0066 0.0063
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0014 0.0064
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.047 0.0468
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0037 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0039 0.0013 0.0011
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0039 0.0013 0.0011
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0093 0.0452
Schistosoma mansoni ap endonuclease 0.0037 0.0008 0.0006
Echinococcus granulosus ATP dependent DNA helicase Q5 0.005 0.0046 0.0043
Onchocerca volvulus 0.0133 0.0277 0.1381
Loa Loa (eye worm) acetylcholine receptor protein 0.0133 0.0277 0.0609
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0122 0.0247 0.1554
Loa Loa (eye worm) RNA binding protein 0.0064 0.0084 0.0185
Echinococcus granulosus acetylcholinesterase 0.0065 0.0088 0.0085
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0056 0.0061 0.0058
Plasmodium falciparum 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.0745 0.1986 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0143 0.0304 0.1517
Onchocerca volvulus Neuropeptide F receptor homolog 0.0041 0.002 0.0083
Brugia malayi G-protein coupled receptor 0.0041 0.002 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Onchocerca volvulus 0.0041 0.002 0.0083
Brugia malayi Fibulin-1 precursor 0.0097 0.0176 0.0379
Echinococcus granulosus g-protein coupled receptor 0.0041 0.002 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus multilocularis dnaJ subfamily B 0.2921 0.8058 0.8058
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0075 0.0459
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0062 0.008 0.0368
Toxoplasma gondii subtilisin SUB12 0.0176 0.0395 0.0523
Loa Loa (eye worm) hypothetical protein 0.0445 0.1147 0.2522
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Echinococcus granulosus enteropeptidase 0.0056 0.0061 0.0058
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0062 0.008 0.0368
Plasmodium vivax NAD-dependent deacetylase, putative 0.0071 0.0103 0.0504
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Onchocerca volvulus 0.0041 0.002 0.0083
Loa Loa (eye worm) notch protein 0.0037 0.0009 0.0019
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0091 0.0088
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Onchocerca volvulus 0.0037 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus multilocularis serotonin receptor 0.0041 0.002 0.0017
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0124 0.0121
Schistosoma mansoni neuropeptide F-like receptor 0.0041 0.002 0.0017
Echinococcus granulosus lamin 0.0083 0.0136 0.0133
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0041 0.002 0.0017
Onchocerca volvulus 0.0176 0.0395 0.1977
Mycobacterium ulcerans hypothetical protein 0.0056 0.0061 0.0272
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0041 0.002 0.0017
Onchocerca volvulus 0.0289 0.0711 0.3572
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0076 0.035
Loa Loa (eye worm) transcriptional regulator 0.0071 0.0103 0.0227
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0162 0.0357 0.0354
Schistosoma mansoni cpg binding protein 0.0221 0.0521 0.0519
Brugia malayi PHD-finger family protein 0.0063 0.008 0.0169
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Leishmania major silent information regulator 2, putative 0.0375 0.0952 0.6054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.008 0.0129 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0062 0.008 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0043 0.0041
Brugia malayi Serotonin receptor 0.0041 0.002 0.0036
Echinococcus multilocularis enteropeptidase 0.0056 0.0061 0.0058
Echinococcus granulosus serotonin receptor 0.0041 0.002 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Leishmania major hypothetical protein, conserved 0.0215 0.0505 0.3204
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0176 0.0395 0.0523
Schistosoma mansoni cpg binding protein 0.0221 0.0521 0.0519
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Echinococcus granulosus neuropeptides capa receptor 0.0041 0.002 0.0017
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.008 0.0129 0.0799
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0133 0.0277 0.0275
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0041 0.002 0.0017
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0368 0.1827
Echinococcus multilocularis fibropellin Ia 0.0037 0.0009 0.0006
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0041 0.002 0.0044
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Schistosoma mansoni neuropeptide receptor 0.0041 0.002 0.0017
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0075 0.0115 0.069
Brugia malayi hypothetical protein 0.0056 0.0061 0.0126
Brugia malayi Galactoside-binding lectin family protein 0.0121 0.0242 0.0524
Schistosoma mansoni hypothetical protein 0.0176 0.0398 0.0395
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Echinococcus multilocularis G protein coupled receptor 139 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0097 0.0176 0.0386
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0041 0.002 0.0017
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0075 0.0459
Brugia malayi follicle stimulating hormone receptor 0.0041 0.002 0.0036
Leishmania major sir2-family protein-like protein 0.0071 0.0103 0.0638
Echinococcus multilocularis cysteine protease 0.0035 0.0004 0.0001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus glycoprotein Antigen 5 0.0056 0.0061 0.0058
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.002 0.0017
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0084 0.0081
Echinococcus granulosus somatostatin receptor 0.0041 0.002 0.0017
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0133 0.0277 0.0275
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0289 0.0711 0.1564
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0039 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0007 0.0021
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0039 0.0013 0.0011
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0289 0.0711 0.0709
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0368 0.0366
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.005 0.0046 0.0043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0099 0.0183 0.089
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0097 0.0176 0.0386
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0162 0.0357 0.0354
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Echinococcus granulosus delta-like protein 1 0.0037 0.0009 0.0006
Echinococcus granulosus Tolloid protein 1 0.0097 0.0176 0.0173
Loa Loa (eye worm) acetylcholinesterase 1 0.0065 0.0088 0.0194
Echinococcus multilocularis protein jagged 2 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Loa Loa (eye worm) GABA receptor subunit 0.0156 0.034 0.0747
Onchocerca volvulus 0.0041 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0118 0.0235 0.0516
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0056 0.0061 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0067 0.0093 0.009
Loa Loa (eye worm) hypothetical protein 0.0166 0.0368 0.081
Brugia malayi Galactoside-binding lectin family protein 0.0121 0.0242 0.0524
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0043 0.0041
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0041 0.002 0.0036
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.008 0.0129 0.0126
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0289 0.0711 0.0709
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0062 0.008 0.0368
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0093 0.0452
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0325 0.0813 0.1079
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0581 0.1526 0.1524
Echinococcus multilocularis nAChR subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0041 0.002 0.0044
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0067 0.0093 0.009
Onchocerca volvulus 0.0156 0.034 0.1696
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi Serotonin receptor 0.0041 0.002 0.0036
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.0773 0.17
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0062 0.008 0.0487
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.005 0.0046 0.0093
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.008 0.0129 0.0126
Loa Loa (eye worm) RecQ helicase 0.0063 0.0081 0.0178
Schistosoma mansoni hypothetical protein 0.0176 0.0398 0.0395
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0007 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0041 0.002 0.0017
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0066 0.0297
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0075 0.0115 0.0245
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Echinococcus granulosus biogenic amine 5HT receptor 0.0041 0.002 0.0017
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi mbt repeat family protein 0.0049 0.0043 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0086 0.0083
Echinococcus granulosus dro:myosuppressin receptor 0.0041 0.002 0.0017
Schistosoma mansoni cpg binding protein 0.0205 0.0478 0.0475
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0375 0.0952 0.0949
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0218 0.0513 0.1122
Leishmania major lanosterol synthase, putative 0.0056 0.006 0.0363
Plasmodium vivax phosphodiesterase gamma, putative 0.008 0.0129 0.0631
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0075 0.0115 0.0561
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0133 0.0276 0.0273
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0062 0.008 0.0466
Loa Loa (eye worm) G-protein coupled receptor 0.0041 0.002 0.0044
Echinococcus granulosus dna polymerase kappa 0.0057 0.0066 0.0063
Onchocerca volvulus 0.0056 0.0061 0.0289
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0007 0.0017
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0043 0.0201
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.008 0.0129 0.0126
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Schistosoma mansoni hypothetical protein 0.0151 0.0326 0.0323
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.002 0.0017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0338 0.0848 0.0846
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0071 0.0103 0.0101
Mycobacterium tuberculosis Probable 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF (MECPS) 0.0598 0.1574 0.7916
Schistosoma mansoni bromodomain containing protein 0.0141 0.0299 0.0297
Schistosoma mansoni hypothetical protein 0.0041 0.002 0.0017
Brugia malayi Pre-SET motif family protein 0.0098 0.0178 0.0385
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0067 0.0093 0.0452
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0062 0.008 0.0368
Onchocerca volvulus 0.0056 0.0061 0.0289
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.0393 0.0857
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0325 0.0813 0.5161
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0007 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0066 0.0396
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0289 0.0711 0.0709
Toxoplasma gondii microneme protein MIC17B 0.0176 0.0395 0.0523
Schistosoma mansoni opsin-like receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0121 0.0242 0.0532
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0133 0.0276 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Trypanosoma brucei SIR2-like protein 4, putative 0.0071 0.0103 0.0618
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0368 0.2308
Schistosoma mansoni ephrin receptor 0.0067 0.0093 0.0091
Schistosoma mansoni alpha-glucosidase 0.015 0.0325 0.0322
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0076 0.035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Brugia malayi hypothetical protein 0.0445 0.1147 0.2516
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0307 0.1517
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0075 0.0438
Echinococcus granulosus laminin 0.0097 0.0176 0.0173
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0008 0.0007
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0124 0.1267
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0014 0.0051
Brugia malayi G protein-coupled receptor 0.0041 0.002 0.0036
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0053 0.0053 0.0232
Leishmania major hypothetical protein, conserved 0.008 0.0129 0.0799
Leishmania major hypothetical protein, conserved 0.0078 0.0124 0.0768
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.015 0.0324 0.0321
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0004 0.0001
Brugia malayi Phosphoglycerate kinase 0.0166 0.0368 0.0803
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0062 0.008 0.0368
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.011 0.0108
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0066 0.0396
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.0326 0.071
Schistosoma mansoni chromatin regulatory protein sir2 0.0071 0.0103 0.0101
Brugia malayi FXNA 0.0039 0.0013 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Echinococcus multilocularis glycine receptor subunit beta 0.0289 0.0711 0.0709
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Mycobacterium tuberculosis Conserved hypothetical protein 0.0314 0.0782 0.3916
Leishmania major cathepsin L-like protease 0.0134 0.0279 0.1762
Trypanosoma brucei DNA polymerase eta, putative 0.0057 0.0066 0.0376
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Toxoplasma gondii microneme protein, putative 0.0176 0.0395 0.0523
Plasmodium falciparum phosphodiesterase gamma, putative 0.008 0.0129 0.0631
Onchocerca volvulus 0.0041 0.002 0.0083
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0097 0.0176 0.0173
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0093 0.0572
Brugia malayi hypothetical protein 0.0133 0.0277 0.0602
Brugia malayi Trypsin family protein 0.0056 0.0061 0.0126
Brugia malayi larval opioid receptor 0.0041 0.002 0.0036
Schistosoma mansoni hypothetical protein 0.0381 0.0969 0.0967
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0062 0.008 0.0368
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0375 0.0952 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0129 0.0283
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0029
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0041 0.002 0.0017
Echinococcus granulosus neurogenic locus notch protein 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0091 0.0201
Echinococcus granulosus orexin receptor type 2 0.0041 0.002 0.0017
Brugia malayi Carboxylesterase family protein 0.0065 0.0088 0.0186
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0325 0.0813 0.5172
Toxoplasma gondii PAN/Apple domain-containing protein 0.0176 0.0395 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0066 0.0297
Toxoplasma gondii histone lysine methyltransferase SET1 0.0397 0.1013 0.1345
Toxoplasma gondii histone deacetylase SIR2 0.0071 0.0103 0.0135
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0029 0.0063
Trichomonas vaginalis helicase, putative 0.0046 0.0035 0.0159
Onchocerca volvulus 0.0151 0.0326 0.1628
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) fibroinase 0.0035 0.0004 0.0008
Brugia malayi Latrophilin receptor protein 2 0.0176 0.0398 0.0867
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.008 0.0129 0.0799
Toxoplasma gondii PAN domain-containing protein 0.0176 0.0395 0.0523
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Schistosoma mansoni jumonji domain containing protein 0.0141 0.0298 0.0295
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.0393 0.0864
Echinococcus multilocularis dro:myosuppressin receptor 0.0041 0.002 0.0017
Trypanosoma brucei glucosidase, putative 0.0039 0.0014 0.0043
Brugia malayi AKH receptor 0.0041 0.002 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0007 0.0017
Schistosoma mansoni hypothetical protein 0.0056 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Onchocerca volvulus 0.0176 0.0395 0.1977
Echinococcus granulosus glycine receptor subunit beta 0.0289 0.0711 0.0709
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0063 0.006
Schistosoma mansoni hypothetical protein 0.0041 0.002 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.0057 0.0054
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0121 0.0242 0.0532
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0289 0.0711 0.0709
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0036 0.0005 0.0006
Onchocerca volvulus 0.0041 0.002 0.0083
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0041 0.002 0.0036
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0176 0.0398 0.0395
Brugia malayi beta-lactamase family protein 0.0036 0.0007 0.0007
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0014 0.0106
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0062 0.008 0.0368
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0049 0.0042 0.0195
Echinococcus granulosus lysine specific demethylase 5A 0.0113 0.022 0.0217
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.1663 0.4548 0.4547
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) PAN domain-containing protein 0.0176 0.0395 0.0869
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.005 0.0046 0.0058
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0368 0.385
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0062 0.008 0.0368
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0289 0.0711 0.1564
Leishmania major DNA polymerase kappa, putative 0.0057 0.0066 0.0396
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0041 0.002 0.0017
Plasmodium falciparum cGMP-specific phosphodiesterase 0.008 0.0129 0.0631
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0279 0.1762
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0066 0.0313
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0091 0.0559
Brugia malayi Fibroblast growth factor family protein 0.0055 0.006 0.0124
Echinococcus multilocularis notch 0.0037 0.0009 0.0006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0007 0.0007
Onchocerca volvulus 0.0176 0.0395 0.1977
Loa Loa (eye worm) hypothetical protein 0.0055 0.006 0.0132
Echinococcus granulosus neuropeptide s receptor 0.2453 0.6753 0.6752
Echinococcus multilocularis slit 2 protein 0.0037 0.0009 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0368 0.1841
Loa Loa (eye worm) histone methyltransferase 0.0067 0.0092 0.0202
Loa Loa (eye worm) ACC-1 protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0027
Toxoplasma gondii microneme protein MIC4 0.0176 0.0395 0.0523
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0014 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0007 0.0004
Schistosoma mansoni alpha-glucosidase 0.015 0.0325 0.0322
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0368 0.1842
Loa Loa (eye worm) melatonin receptor type 1A 0.0041 0.002 0.0044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1312 0.3568 0.3567
Echinococcus multilocularis Tolloid protein 1 0.0097 0.0176 0.0173
Mycobacterium ulcerans Sir2-like regulatory protein 0.0071 0.0103 0.0488
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0279 0.1762
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0375 0.0952 0.4784
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) hypothetical protein 0.0097 0.0175 0.0385
Leishmania major cytochrome p450-like protein 0.0062 0.008 0.0487
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0599 0.1317
Onchocerca volvulus 0.0056 0.0061 0.0289
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi hypothetical protein 0.0051 0.0046 0.0094
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) hypothetical protein 0.0097 0.0175 0.0385
Onchocerca volvulus 0.0041 0.002 0.0083
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0066 0.0063
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0289 0.0711 0.0709
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0016 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0004 0.0001
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0039 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.1229 0.3335 0.3333
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.008 0.0129 0.0126
Echinococcus granulosus g protein coupled receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0014 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.002 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0136 0.0298
Loa Loa (eye worm) hypothetical protein 0.047 0.1216 0.2673
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0043 0.0041
Onchocerca volvulus 0.0289 0.0711 0.3572
Schistosoma mansoni nAChR subunit 0.0133 0.0277 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Toxoplasma gondii 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase domain-containing protein 0.0745 0.1986 0.2639
Loa Loa (eye worm) galectin 0.0121 0.0242 0.0532
Loa Loa (eye worm) Notch2 0.0037 0.0009 0.0019
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0066 0.0376
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0008 0.0009
Echinococcus granulosus protein jagged 1 0.0037 0.0009 0.0006
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.047 0.1216 0.1214
Loa Loa (eye worm) hypothetical protein 0.0133 0.0276 0.0606
Echinococcus multilocularis survival motor neuron protein 1 0.0739 0.1968 0.1966
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0013 0.0049
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0218 0.0513 0.0511
Echinococcus multilocularis hormone sensitive lipase 0.047 0.1216 0.1214
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0039 0.0013 0.0011
Brugia malayi Cytochrome P450 family protein 0.0062 0.008 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Onchocerca volvulus 0.0041 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0083 0.0136 0.0298
Schistosoma mansoni hypothetical protein 0.2921 0.8058 0.8058
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0071 0.0103 0.0504
Treponema pallidum phosphoglycerate kinase 0.0166 0.0368 0.1822
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0084 0.0185
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus granulosus g protein coupled receptor 0.0041 0.002 0.0017
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0134 0.0279 0.0276
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0071 0.0103 0.0638
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0558 0.1462 0.3213
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0014 0.0051
Brugia malayi Trypsin family protein 0.0056 0.0061 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0215 0.0505 0.3189
Onchocerca volvulus Neurogenic locus notch homolog 0.0037 0.0009 0.0025
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0066 0.0144
Loa Loa (eye worm) norepinephrine transporter 0.0097 0.0175 0.0385
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0289 0.0711 0.0709
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0194
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0075 0.0115 0.071
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0375 0.0952 1
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0075 0.0115 0.0561
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0289 0.0711 0.1564
Echinococcus granulosus chromatin regulatory protein sir2 0.0375 0.0952 0.0949
Echinococcus granulosus ATP dependent DNA helicase Q1 0.005 0.0046 0.0043
Schistosoma mansoni neuropeptide receptor 0.0041 0.002 0.0017
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0282 0.0693 0.439
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0066 0.0297
Giardia lamblia Hypothetical protein 0.0055 0.006 0.055
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.008 0.0129 0.0283
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0368 0.2331
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0041 0.002 0.0017
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0004 0.0008
Onchocerca volvulus 0.0041 0.002 0.0083
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0056 0.0061 0.0058
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0124 0.0607
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0134 0.0279 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0014 0.0064
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Wolbachia endosymbiont of Brugia malayi 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.0745 0.1986 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0004 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Giardia lamblia Fructose-bisphosphate aldolase 0.0295 0.0728 0.7627
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0081 0.0131 0.0289
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0393 0.039
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0056 0.0061 0.0058
Schistosoma mansoni lamin 0.0083 0.0136 0.0133
Echinococcus multilocularis fat cadherin tumor suppressor 0.0037 0.0009 0.0006
Loa Loa (eye worm) sirtuin 4 0.0071 0.0103 0.0227
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0067 0.0093 0.0452
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0062 0.008 0.0368
Brugia malayi Calcium binding EGF domain containing protein 0.0097 0.0176 0.0379
Echinococcus granulosus Mastin 0.0056 0.0061 0.0058
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0007 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0178 0.0176
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0046 0.0035 0.0159
Loa Loa (eye worm) TYRA-2 protein 0.0041 0.002 0.0044
Onchocerca volvulus 0.0041 0.002 0.0083
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0097 0.0175 0.0385
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0133 0.0277 0.0602
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0192 0.0442 0.2212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0289 0.0711 0.0709
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0124 0.0767
Brugia malayi hypothetical protein 0.0739 0.1968 0.4323
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0081
Onchocerca volvulus 0.0098 0.0178 0.0882
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0095
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0289 0.0711 0.1558
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0057
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0121 0.0242 0.0532
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Echinococcus granulosus glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Loa Loa (eye worm) CXXC zinc finger family protein 0.0205 0.0478 0.105
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0192 0.0442 0.4597
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Echinococcus multilocularis glycine receptor subunit beta 0.0289 0.0711 0.0709
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0063 0.006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0041 0.002 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0039 0.0013 0.0011
Entamoeba histolytica hypothetical protein 0.015 0.0324 0.338
Entamoeba histolytica hypothetical protein, conserved 0.0071 0.0103 0.1053
Loa Loa (eye worm) cytochrome P450 family protein 0.0221 0.0522 0.1148
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis transmembrane protease serine 3 0.0056 0.0061 0.0058
Brugia malayi hypothetical protein 0.015 0.0324 0.0705
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Loa Loa (eye worm) CYP4Cod1 0.0099 0.0183 0.0402
Loa Loa (eye worm) neuropeptide F receptor 0.0041 0.002 0.0044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0076 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0338 0.0848 0.0846
Toxoplasma gondii hypothetical protein 0.0176 0.0395 0.0523
Toxoplasma gondii hypothetical protein 0.0075 0.0115 0.015
Schistosoma mansoni sodium/chloride dependent transporter 0.0097 0.0175 0.0173
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0053 0.0294
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Brugia malayi ORL1-like opioid receptor 0.0041 0.002 0.0036
Trypanosoma cruzi DNA polymerase eta, putative 0.0057 0.0066 0.0396
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0139 0.0867
Schistosoma mansoni acetylcholine receptor subunit beta 0.0133 0.0277 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Echinococcus multilocularis 0.0062 0.008 0.0077
Trypanosoma brucei unspecified product 0.004 0.0016 0.0057
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0023 0.0051
Entamoeba histolytica recQ family helicase, putative 0.0053 0.0053 0.052
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0008 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0007 0.0021
Giardia lamblia Prenyltransferase 0.0067 0.0093 0.09
Echinococcus granulosus cathepsin l1 0.0035 0.0004 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0041 0.002 0.0017
Trypanosoma brucei unspecified product 0.0057 0.0066 0.0376
Onchocerca volvulus 0.0289 0.0711 0.3572
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.002 0.0017
Echinococcus granulosus survival motor neuron protein 1 0.0739 0.1968 0.1966
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Trichomonas vaginalis DNA helicase recq1, putative 0.0063 0.0081 0.039
Schistosoma mansoni alpha-1 adrenergic receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0289 0.0711 0.1564
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0065 0.0088 0.0194
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus granulosus acetylcholinesterase 0.0065 0.0088 0.0085
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0218 0.0513 0.2573
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1663 0.4548 0.4547
Schistosoma mansoni biogenic amine (5HT) receptor 0.0041 0.002 0.0017
Treponema pallidum sodium- and chloride- dependent transporter 0.0097 0.0175 0.0845
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.0554 0.2764
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Schistosoma mansoni growth hormone secretagogue receptor 0.0041 0.002 0.0017
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0043 0.0041
Echinococcus granulosus cpg binding protein 0.0221 0.0521 0.0519
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0338 0.0848 0.0846
Echinococcus multilocularis neuropeptides capa receptor 0.0041 0.002 0.0017
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0075 0.0115 0.071
Trypanosoma brucei unspecified product 0.004 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Mycobacterium leprae Probable 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF (MECPS) (MECDP-synthase ) 0.0598 0.1574 1
Toxoplasma gondii cathepsin CPL 0.0035 0.0004 0.0002
Toxoplasma gondii cytochrome p450 superfamily protein 0.0062 0.008 0.0103
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0091 0.0193
Echinococcus granulosus glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Loa Loa (eye worm) carboxylesterase 0.0065 0.0088 0.0194
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0505 0.3204
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.038 0.0967 0.0965
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus Galectin carbohydrate recognition domain 0.0121 0.0242 0.0239
Echinococcus granulosus protein jagged 1 0.0037 0.0009 0.0006
Loa Loa (eye worm) inositol-1 0.0078 0.0124 0.0272
Echinococcus multilocularis cpg binding protein 0.0221 0.0521 0.0519
Schistosoma mansoni slit 0.0037 0.0009 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0066 0.0376
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0062 0.008 0.0368
Brugia malayi transcriptional regulator, Sir2 family protein 0.0071 0.0103 0.022
Echinococcus multilocularis protein jagged 1 0.0037 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0067 0.0093 0.0945
Schistosoma mansoni opsin-like receptor 0.0041 0.002 0.0017
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0091 0.0924
Toxoplasma gondii microneme protein MIC17C 0.0176 0.0395 0.0523
Brugia malayi G-protein coupled receptor 0.0041 0.002 0.0036
Onchocerca volvulus 0.0041 0.002 0.0083
Echinococcus granulosus neuropeptide receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0075 0.0115 0.069
Trypanosoma brucei lanosterol synthase 0.0074 0.0111 0.0669
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0133 0.0277 0.0609
Echinococcus multilocularis glycoprotein Antigen 5 0.0056 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0027
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Onchocerca volvulus 0.0083 0.0136 0.0667
Onchocerca volvulus Galectin homolog 0.0121 0.0242 0.1202
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0004 0.0001
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0375 0.0952 0.6046
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0325 0.0813 0.4085
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.0728 0.7638
Toxoplasma gondii PAN domain-containing protein 0.0176 0.0395 0.0523
Toxoplasma gondii PAN domain-containing protein 0.0176 0.0395 0.0523
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Onchocerca volvulus 0.0133 0.0277 0.1381
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0307 0.1916
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0289 0.0711 0.1558
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1663 0.4548 0.4547
Schistosoma mansoni inositol monophosphatase 0.0078 0.0124 0.0121
Brugia malayi Phosphoglycerate kinase 0.0061 0.0075 0.0158
Brugia malayi jmjC domain containing protein 0.0113 0.022 0.0476
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0004 0.0001
Onchocerca volvulus 0.0176 0.0395 0.1977
Onchocerca volvulus 0.0036 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0063 0.0138
Schistosoma mansoni hypothetical protein 0.0308 0.0766 0.0763
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0375 0.0952 0.6054
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0041 0.002 0.0044
Leishmania major mitochondrial DNA polymerase beta 0.0596 0.1569 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0076 0.035
Onchocerca volvulus Fxna peptidase homolog 0.0039 0.0013 0.0049
Echinococcus granulosus geminin 0.1229 0.3335 0.3333
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0289 0.0711 0.0709
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0065 0.0088 0.0085
Echinococcus granulosus tachykinin peptides receptor 99D 0.0041 0.002 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.015 0.0324 0.0321
Schistosoma mansoni hypothetical protein 0.0176 0.0398 0.0395
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0043 0.0041
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0056 0.0061 0.0126
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0075 0.0115 0.071
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0282 0.0693 0.4402
Brugia malayi Galactoside-binding lectin family protein 0.0121 0.0242 0.0524
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.008 0.0129 0.0799
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Onchocerca volvulus 0.0289 0.0711 0.3572
Onchocerca volvulus 0.0176 0.0395 0.1977
Brugia malayi hypothetical protein 0.0133 0.0277 0.0602
Brugia malayi Fibroblast growth factor family protein 0.0055 0.006 0.0124
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0039 0.0013 0.0049
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0062 0.008 0.0487
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0041 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0078 0.0124 0.0273
Loa Loa (eye worm) PAN domain-containing protein 0.0176 0.0395 0.0869
Entamoeba histolytica hypothetical protein 0.015 0.0324 0.338
Echinococcus granulosus glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0027 0.0024
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0054 0.0057 0.0054
Schistosoma mansoni egf-like domain protein 0.0097 0.0176 0.0173
Loa Loa (eye worm) hypothetical protein 0.0558 0.1462 0.3213
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0192 0.0442 0.0439
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Brugia malayi Cadherin domain containing protein 0.0037 0.0009 0.0011
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.008 0.0129 0.0126
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0041 0.002 0.0044
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0091 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0081
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0395 0.1007 0.2213
Echinococcus multilocularis neuropeptide Y receptor 0.0041 0.002 0.0017
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0393 0.039
Brugia malayi Galactoside-binding lectin family protein 0.0121 0.0242 0.0524
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0062 0.008 0.0368
Brugia malayi Calcitonin receptor-like protein seb-1 0.0558 0.1462 0.3208
Loa Loa (eye worm) hypothetical protein 0.0097 0.0176 0.0386
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Onchocerca volvulus 0.0176 0.0395 0.1977
Toxoplasma gondii histone deacetylase SIR2-like 0.0071 0.0103 0.0135
Schistosoma mansoni histamine h1 receptor 0.0041 0.002 0.0017
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0067 0.0093 0.0452
Loa Loa (eye worm) MBCTL1 0.0056 0.0063 0.0138
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0041 0.002 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0289 0.0711 0.1558
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0076 0.0464
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0542 0.1418 0.3117
Brugia malayi beta-lactamase 0.0036 0.0007 0.0007
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0007 0.0015
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0066 0.0063
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0133 0.0277 0.0609
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0368 0.0487
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0325 0.0813 0.5172
Leishmania major cytochrome p450-like protein 0.0099 0.0183 0.1146
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.008 0.0129 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.0144
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0062 0.008 0.0368
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Echinococcus multilocularis GPCR, family 2 0.0176 0.0398 0.0395
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0062 0.008 0.0368
Brugia malayi galectin 0.0121 0.0242 0.0524
Loa Loa (eye worm) cytochrome P450 0.0062 0.008 0.0175
Entamoeba histolytica hypothetical protein 0.015 0.0324 0.338
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Onchocerca volvulus 0.0289 0.0711 0.3572
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0368 0.0366
Brugia malayi jmjC domain containing protein 0.0162 0.0357 0.0777
Schistosoma mansoni DNA helicase recq5 0.005 0.0046 0.0043
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.022 0.0217
Echinococcus multilocularis bloom syndrome protein 0.0063 0.0081 0.0078
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Echinococcus granulosus alpha 1A adrenergic receptor 0.0041 0.002 0.0017
Toxoplasma gondii exonuclease III APE 0.0037 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Echinococcus granulosus transmembrane protease serine 3 0.0056 0.0061 0.0058
Brugia malayi NAD-dependent deacetylase SIRT1 0.0192 0.0442 0.0965
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0067 0.0093 0.0121
Loa Loa (eye worm) hypothetical protein 0.0121 0.0242 0.0532
Echinococcus granulosus peregrin 0.0036 0.0006 0.0003
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.1663 0.4548 1
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0075 0.0115 0.0252
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0062 0.008 0.0368
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0008 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0041 0.002 0.0017
Brugia malayi F/Y-rich N-terminus family protein 0.008 0.0129 0.0277
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0084 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0129 0.0631
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0097 0.0176 0.0386
Echinococcus multilocularis cysteine protease 0.0035 0.0004 0.0001
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0289 0.0711 0.1564
Schistosoma mansoni septate junction protein 0.0037 0.0009 0.0006
Schistosoma mansoni lozenge 0.0056 0.0061 0.0058
Onchocerca volvulus Fxna peptidase homolog 0.0039 0.0013 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0007 0.0017
Echinococcus granulosus serotonin transporter 0.0097 0.0175 0.0173
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0066 0.0396
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0076 0.0099
Onchocerca volvulus 0.0289 0.0711 0.3572
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0091 0.0559
Onchocerca volvulus 0.0037 0.0009 0.0025
Echinococcus granulosus neurogenic locus notch protein 4 0.0037 0.0009 0.0006
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0368 0.1841
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0156 0.034 0.0337
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0218 0.0513 0.5378
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0655 0.1734 0.3813
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0075 0.0459
Brugia malayi Bromodomain containing protein 0.0165 0.0366 0.0798
Leishmania major cathepsin L-like protease 0.0134 0.0279 0.1762
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0178 0.0176
Echinococcus multilocularis lamin 0.0083 0.0136 0.0133
Mycobacterium ulcerans NAD-dependent deacetylase 0.0071 0.0103 0.0488
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0289 0.0711 0.0709
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0075 0.0115 0.069
Schistosoma mansoni chromatin regulatory protein sir2 0.0192 0.0442 0.0439
Leishmania major farnesyltransferase beta subunit 0.0067 0.0093 0.0572
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0136 0.0298
Giardia lamblia DINP protein human, muc B family 0.0057 0.0066 0.0608
Onchocerca volvulus 0.0067 0.0091 0.0443
Echinococcus multilocularis g-protein coupled receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0098 0.0178 0.0176
Echinococcus granulosus allatostatin A receptor 0.0041 0.002 0.0017
Mycobacterium leprae putative cytochrome p450 0.0062 0.008 0.0465
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0062 0.008 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0066 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Schistosoma mansoni nAChR subunit 0.0133 0.0277 0.0275
Leishmania major hypothetical protein, conserved 0.008 0.0129 0.0799
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0289 0.0711 0.0709
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0097 0.0175 0.0173
Plasmodium falciparum cGMP-specific phosphodiesterase 0.008 0.0129 0.0631
Toxoplasma gondii hypothetical protein 0.0176 0.0395 0.0523
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.0393 0.039
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0133 0.0277 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0124 0.0768
Schistosoma mansoni neurotransmitter gated ion channel 0.0133 0.0277 0.0275
Brugia malayi excitatory GABA receptor EXP-1A 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Leishmania major hypothetical protein, conserved 0.0036 0.0007 0.0021
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus neurogenic locus protein delta 0.0037 0.0009 0.0006
Echinococcus multilocularis carboxylesterase 5A 0.0065 0.0088 0.0085
Toxoplasma gondii PAN domain-containing protein 0.2728 0.7519 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0063 0.006
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0075 0.0459
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0779
Loa Loa (eye worm) hypothetical protein 0.0145 0.0309 0.068
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0115 0.069
Loa Loa (eye worm) trypsin family protein 0.0056 0.0061 0.0134
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0062 0.008 0.0368
Onchocerca volvulus 0.0163 0.036 0.18
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0071 0.0103 0.0101
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0062 0.008 0.0487
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.008 0.0129 0.0126
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0223 0.0221
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.047 0.0468
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0071 0.0103 0.0638
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0058 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.006 0.0074 0.0353
Loa Loa (eye worm) LGC-31 protein 0.0289 0.0711 0.1564
Trypanosoma cruzi cruzipain precursor, putative 0.0134 0.0279 0.1762
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0063 0.006
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0066 0.0137
Echinococcus granulosus neuropeptides capa receptor 0.0041 0.002 0.0017
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0178 0.0235
Schistosoma mansoni zinc finger protein 0.0052 0.005 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0007 0.0017
Brugia malayi Dopamine receptor 0.0041 0.002 0.0036
Leishmania major cathepsin L-like protease 0.0134 0.0279 0.1762
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0037 0.0009 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0133 0.0276 0.0273
Loa Loa (eye worm) hypothetical protein 0.0156 0.034 0.0747
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Echinococcus multilocularis neuropeptide receptor 0.0041 0.002 0.0017
Brugia malayi Dopamine receptor protein 1 0.0041 0.002 0.0036
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0124 0.0583
Mycobacterium ulcerans 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.0745 0.1986 1
Loa Loa (eye worm) beta-lactamase 0.0036 0.0007 0.0015
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0325 0.0813 0.0811
Toxoplasma gondii hypothetical protein 0.0096 0.0174 0.0228
Brugia malayi Cadherin domain containing protein 0.0037 0.0009 0.0011
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0375 0.0952 0.4784
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Echinococcus granulosus fetal alzheimer antigen falz 0.0058 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0445 0.1147 0.2522
Schistosoma mansoni Fxna peptidase (M28 family) 0.0039 0.0013 0.0011
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0075 0.0115 0.0112
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0558 0.1462 0.3208
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus g protein coupled receptor 0.0041 0.002 0.0017
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0596 0.1569 1
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Echinococcus granulosus hypothetical protein 0.0041 0.002 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0062 0.008 0.0368
Toxoplasma gondii EGF family domain-containing protein 0.0037 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0067 0.0093 0.0552
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.008 0.0129 0.0275
Schistosoma mansoni chromatin regulatory protein sir2 0.0071 0.0103 0.0101
Schistosoma mansoni amine GPCR 0.0041 0.002 0.0017
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0779
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0111 0.0689
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0133 0.0277 0.0275
Echinococcus granulosus glycine receptor subunit beta 0.0289 0.0711 0.0709
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0115 0.071
Echinococcus multilocularis fibrillin 1 0.0097 0.0176 0.0173
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Echinococcus granulosus fibropellin Ia 0.0037 0.0009 0.0006
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0013 0.001
Echinococcus multilocularis musashi 0.0083 0.0136 0.0133
Onchocerca volvulus 0.0083 0.0136 0.0667
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0133 0.0277 0.0275
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0062 0.008 0.0368
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0093 0.0452
Echinococcus multilocularis neurogenic locus notch protein 0.0037 0.0009 0.0006
Onchocerca volvulus 0.0745 0.1985 1
Trypanosoma cruzi cytochrome P450, putative 0.0099 0.0183 0.1146
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0004 0.0001
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0053 0.0053 0.0232
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0008 0.001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0368 0.2331
Brugia malayi Cytochrome P450 family protein 0.0099 0.0183 0.0395
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0041 0.002 0.0017
Brugia malayi hypothetical protein 0.0133 0.0277 0.0602
Brugia malayi putative neuropeptide receptor 0.0041 0.002 0.0036
Mycobacterium ulcerans hypothetical protein 0.0314 0.0782 0.3916
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0218 0.0513 0.0511
Onchocerca volvulus 0.0041 0.002 0.0083
Echinococcus multilocularis snurportin 1 0.0311 0.0773 0.0771
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Brugia malayi GnHR receptor homolog 0.0041 0.002 0.0036
Echinococcus multilocularis sex peptide receptor 0.0041 0.002 0.0017
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0041 0.002 0.0017
Echinococcus granulosus protein jagged 2 0.0037 0.0009 0.0006
Schistosoma mansoni amine GPCR 0.0041 0.002 0.0017
Giardia lamblia hypothetical protein 0.008 0.0129 0.1277
Echinococcus multilocularis neuropeptide s receptor 0.2453 0.6753 0.6752
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0156 0.034 0.0739
Echinococcus multilocularis g protein coupled receptor 0.0041 0.002 0.0017
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0008 0.0006
Onchocerca volvulus 0.0056 0.0061 0.0289
Brugia malayi Bromodomain containing protein 0.0078 0.0124 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0239 0.0571 0.0569
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0124 0.0747
Trichomonas vaginalis DNA helicase recq, putative 0.0063 0.0081 0.039
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0014 0.0015
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0368 0.1822
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0063 0.013
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0084 0.0177
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0009 0.0011
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0093 0.0205
Echinococcus multilocularis neural cadherin 0.0037 0.0009 0.0006
Brugia malayi galectin 0.0121 0.0242 0.0524
Onchocerca volvulus Glutaminyl cyclase homolog 0.0039 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Echinococcus multilocularis serotonin receptor 0.0041 0.002 0.0017
Echinococcus granulosus histone lysine methyltransferase setb 0.0133 0.0276 0.0273
Echinococcus granulosus ephrin type A receptor 4 A 0.0067 0.0093 0.0091
Echinococcus multilocularis nAChR subunit 0.0156 0.034 0.0337
Echinococcus multilocularis G-protein coupled receptor, putative 0.0041 0.002 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0338 0.0848 0.0846
Schistosoma mansoni chromatin regulatory protein sir2 0.0071 0.0103 0.0101
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0041 0.002 0.0083
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.008 0.0129 0.0126
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0027 0.0024
Loa Loa (eye worm) G-protein coupled receptor 0.0041 0.002 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.002 0.0017
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0062 0.008 0.0368
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0133 0.0277 0.0602
Loa Loa (eye worm) hypothetical protein 0.0192 0.0442 0.0972
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0218 0.0513 0.2572
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0062 0.008 0.0368
Schistosoma mansoni hypothetical protein 0.0311 0.0773 0.0771
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0596 0.1569 1
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0111 0.0689
Chlamydia trachomatis 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.0745 0.1986 1
Loa Loa (eye worm) leucyl aminopeptidase 0.0039 0.0013 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0041 0.002 0.0017
Schistosoma mansoni hypothetical protein 0.0041 0.002 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0004 0.0001
Echinococcus multilocularis neurogenic locus notch protein 4 0.0037 0.0009 0.0006
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0105 0.0199 0.125
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0062 0.008 0.0368
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0338 0.0848 0.0846
Echinococcus multilocularis dna polymerase eta 0.0057 0.0066 0.0063
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0124 0.0606
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Brugia malayi putative neuropeptide receptor NPR1 0.0041 0.002 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0156 0.0154
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0075 0.0115 0.0112
Brugia malayi hypothetical protein 0.0163 0.036 0.0785
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0129 0.0779
Brugia malayi Bloom's syndrome protein homolog 0.0063 0.0081 0.017
Loa Loa (eye worm) solute carrier family 6 member 4 0.0097 0.0175 0.0385
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0124 0.0607
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.047 0.1216 0.1214
Loa Loa (eye worm) hypothetical protein 0.0056 0.0061 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0014 0.0064
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0062 0.008 0.0368
Schistosoma mansoni laminin gamma-3 chain 0.0037 0.0009 0.0006
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0066 0.0063
Onchocerca volvulus 0.0176 0.0395 0.1977
Brugia malayi RNA, U transporter 1 0.0083 0.0137 0.0293
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0066 0.0137
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0121 0.0244 0.0536
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) cytochrome P450 family protein 0.0099 0.0183 0.0402
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0067 0.0093 0.0452
Onchocerca volvulus 0.0041 0.002 0.0083
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0008 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.008 0.0129 0.0275
Schistosoma mansoni alpha glucosidase 0.0039 0.0014 0.0011
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0139 0.0848
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.008 0.0129 0.1277
Toxoplasma gondii microneme protein MIC17A 0.0176 0.0395 0.0523
Echinococcus granulosus expressed protein 0.0381 0.097 0.0967
Entamoeba histolytica hypothetical protein 0.0156 0.034 0.3545
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0008 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0071 0.0103 0.0504
Schistosoma mansoni adenoreceptor 0.0041 0.002 0.0017
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0071 0.0103 0.0618
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.002 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.002 0.0017
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0041 0.002 0.0017
Brugia malayi Trypsin family protein 0.0056 0.0061 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Schistosoma mansoni hypothetical protein 0.0035 0.0003 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Loa Loa (eye worm) transcriptional regulator 0.0071 0.0103 0.0227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0289 0.0711 0.1558
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0124 0.0748
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Brugia malayi Cation transporter family protein 0.0289 0.0711 0.1558
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Toxoplasma gondii PAN domain-containing protein 0.2728 0.7519 1
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.008 0.0129 0.0126
Echinococcus granulosus dna polymerase eta 0.0057 0.0066 0.0063
Echinococcus multilocularis somatostatin receptor 0.0041 0.002 0.0017
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0289 0.0711 0.0709
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0041 0.002 0.0017
Schistosoma mansoni myosin xvIII 0.0041 0.002 0.0017
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0014 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Onchocerca volvulus Putative cubilin 0.0037 0.0009 0.0025
Schistosoma mansoni notch 0.0037 0.0009 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0067 0.0092 0.0089
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0071 0.0103 0.1053
Schistosoma mansoni amine GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Trypanosoma brucei cAMP-specific phosphodiesterase 0.008 0.0129 0.0779
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0133 0.0277 0.0602
Schistosoma mansoni cell polarity protein 0.0037 0.0009 0.0006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0067 0.0092 0.0089
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0066 0.0396
Schistosoma mansoni lipoxygenase 0.008 0.0128 0.0125
Schistosoma mansoni amine GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0008 0.0024
Plasmodium vivax SET domain protein, putative 0.0098 0.0178 0.0882
Echinococcus multilocularis allatostatin A receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) runx1 0.0056 0.0061 0.0134
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0338 0.0848 0.0846
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0368 0.0366
Onchocerca volvulus 0.0041 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0124 0.0162
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0067 0.0093 0.0452
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0093 0.0572
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Onchocerca volvulus 0.0176 0.0395 0.1977
Leishmania major DNA polymerase eta, putative 0.0057 0.0066 0.0396
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Schistosoma mansoni lamin 0.0083 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Echinococcus multilocularis lysine specific demethylase 5A 0.0097 0.0176 0.0174
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0124 0.0767
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.008 0.0129 0.0799
Onchocerca volvulus Galectin homolog 0.0121 0.0242 0.1202
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Echinococcus multilocularis g protein coupled receptor 0.0041 0.002 0.0017
Echinococcus granulosus neuropeptide receptor 0.0041 0.002 0.0017
Echinococcus multilocularis laminin 0.0097 0.0176 0.0173
Brugia malayi Dopamine receptor protein 2 0.0041 0.002 0.0036
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0053 0.0249
Echinococcus multilocularis microtubule associated protein 2 0.3617 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0041 0.002 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0014 0.0051
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0075 0.0459
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0009 0.0007
Mycobacterium tuberculosis Conserved protein 0.0039 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0176 0.0398 0.0395
Schistosoma mansoni hypothetical protein 0.0056 0.0061 0.0058
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0218 0.0513 0.2573
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0035 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0062 0.008 0.0368
Echinococcus granulosus GPCR family 2 0.0176 0.0398 0.0395
Loa Loa (eye worm) PAN domain-containing protein 0.0176 0.0395 0.0869
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0071 0.0103 0.0504
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0279 0.1762
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0218 0.0513 0.2572
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0156 0.034 0.0337
Brugia malayi Inositol-1 0.0078 0.0124 0.0264
Echinococcus multilocularis Protein lozenge 0.0056 0.0061 0.0058
Trypanosoma brucei glutaminyl cyclase, putative 0.0039 0.0013 0.0041
Brugia malayi Melatonin receptor type 1A 0.0041 0.002 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0338 0.0848 0.0846
Onchocerca volvulus Slit protein homolog 0.0037 0.0009 0.0025
Loa Loa (eye worm) serotonin transporter b 0.0097 0.0175 0.0385
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0289 0.0711 0.1558
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Echinococcus multilocularis zinc finger protein 0.0052 0.005 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0062 0.008 0.0368
Brugia malayi MH2 domain containing protein 0.0249 0.0599 0.1311
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0097 0.0176 0.0386
Echinococcus multilocularis lamin dm0 0.0083 0.0136 0.0133
Schistosoma mansoni hypothetical protein 0.1229 0.3335 0.3333
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0076 0.0074
Echinococcus granulosus protein jagged 2 0.0037 0.0009 0.0006
Schistosoma mansoni biogenic amine receptor 0.0041 0.002 0.0017
Echinococcus multilocularis serotonin transporter 0.0097 0.0175 0.0173
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0071 0.0103 0.0504
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0029 0.0055
Leishmania major cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0799
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0014 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0631
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0043 0.0095
Loa Loa (eye worm) galactoside-binding lectin family protein 0.0121 0.0242 0.0532
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0074 0.0111 0.0528
Schistosoma mansoni nAChR subunit 0.0289 0.0711 0.0709
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0085 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0057
Echinococcus multilocularis acetylcholinesterase 0.0065 0.0088 0.0085
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0041 0.002 0.0017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0007 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0076 0.035
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0081
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0124 0.0606
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0289 0.0711 0.0709
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0599 0.1317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0368 0.2331
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0375 0.0952 0.0949
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.005 0.0046 0.0093
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0039 0.0013 0.0011
Echinococcus multilocularis chromatin regulatory protein sir2 0.0375 0.0952 0.0949
Brugia malayi beta-lactamase family protein 0.0036 0.0007 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0062 0.008 0.0368
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0192 0.0442 0.0439
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0014 0.0106
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0071 0.0103 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0041 0.002 0.0017
Echinococcus granulosus sex peptide receptor 0.0041 0.002 0.0017
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.005 0.0046 0.0212
Loa Loa (eye worm) hypothetical protein 0.005 0.0046 0.01
Trichomonas vaginalis esterase, putative 0.0036 0.0007 0.0017
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0191 0.1194
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0101 0.0599
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0368 0.3819
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0014 0.0051
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0058 0.0067 0.0064
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0006 0.0014
Onchocerca volvulus 0.0041 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Loa Loa (eye worm) cytochrome P450 family protein 0.0099 0.0183 0.0402
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0368 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0129 0.0631
Schistosoma mansoni hypothetical protein 0.015 0.0324 0.0321
Echinococcus granulosus fmrfamide receptor 0.0041 0.002 0.0017
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0071 0.0103 0.0504
Brugia malayi Cation transporter family protein 0.0289 0.0711 0.1558
Loa Loa (eye worm) galectin 0.0121 0.0242 0.0532
Echinococcus granulosus neurogenic locus notch protein 0.0037 0.0009 0.0006
Onchocerca volvulus 0.0097 0.0175 0.0867
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Onchocerca volvulus Arrow homolog 0.0097 0.0176 0.0869
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.008 0.0129 0.0126
Brugia malayi latrophilin 2 splice variant baaae 0.0381 0.0969 0.2125
Trypanosoma cruzi glutaminyl cyclase, putative 0.0039 0.0013 0.0063
Giardia lamblia High cysteine protein 0.0037 0.0009 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.047 0.1216 0.1214
Loa Loa (eye worm) hypothetical protein 0.0099 0.0181 0.0399
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0779
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0071 0.0103 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.002 0.0017
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0041 0.002 0.0017
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0043 0.0041
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0223 0.0221
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0289 0.0711 0.0709
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0091 0.0559
Onchocerca volvulus 0.0056 0.0061 0.0289
Brugia malayi Protein kinase domain containing protein 0.0118 0.0235 0.0509
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0061 0.0058
Onchocerca volvulus 0.0037 0.0009 0.0025
Onchocerca volvulus 0.0445 0.1147 0.577
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0124 0.0606
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0063 0.006
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Brugia malayi intermediate filament protein 0.0083 0.0136 0.0291
Giardia lamblia Transcriptional regulator, Sir2 family 0.0071 0.0103 0.1009
Echinococcus granulosus slit 2 protein 0.0037 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Brugia malayi hypothetical protein 0.0078 0.0124 0.0265
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0124 0.0767
Brugia malayi transcriptional regulator, Sir2 family protein 0.0071 0.0103 0.022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0279 0.1744
Brugia malayi Trypsin-like protease protein 5 0.0056 0.0061 0.0126
Brugia malayi G protein-coupled receptor F59B2.13 0.0041 0.002 0.0036
Brugia malayi RNA binding protein 0.0064 0.0084 0.0177
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0066 0.0655
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.0398 0.0867
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0066 0.0297
Plasmodium falciparum phosphodiesterase delta, putative 0.008 0.0129 0.0631
Mycobacterium leprae Conserved hypothetical protein 0.0062 0.008 0.0465
Brugia malayi Bromodomain containing protein 0.0036 0.0006 0.0006
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0041 0.002 0.0017
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.008 0.0129 0.0126
Schistosoma mansoni chromatin regulatory protein sir2 0.0375 0.0952 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0289 0.0711 0.1558
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0289 0.0711 0.0709
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0368 0.0487
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Brugia malayi cytochrome P450 0.0062 0.008 0.0168
Brugia malayi PAN domain containing protein 0.0176 0.0395 0.0862
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0595 0.1565 0.3441
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0016 0.0014
Echinococcus multilocularis neurogenic locus notch protein 0.0037 0.0009 0.0006
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0041 0.002 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0066 0.0376
Brugia malayi hypothetical protein 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Schistosoma mansoni intermediate filament proteins 0.0083 0.0136 0.0133
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0218 0.0513 0.1129
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0728 0.3654
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0338 0.0848 0.1858
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.002 0.0017
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0289 0.0711 0.1558
Schistosoma mansoni opsin-like receptor 0.0041 0.002 0.0017
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.008 0.0129 0.0168
Onchocerca volvulus 0.0176 0.0395 0.1977
Toxoplasma gondii peptidase, M28 family protein 0.0039 0.0013 0.0015
Giardia lamblia Rab geranylgeranyltransferase 0.0075 0.0115 0.1129
Brugia malayi EGF-like domain containing protein 0.0037 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0176 0.0398 0.0874
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0132 0.0275 0.0272
Schistosoma mansoni cytochrome P450 0.0062 0.008 0.0077
Echinococcus granulosus 7TM GPCR rhodopsin 0.0041 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0071 0.0103 0.0638
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0062 0.008 0.0368
Echinococcus granulosus intermediate filament protein 0.0083 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Loa Loa (eye worm) neuropeptide F receptor 0.0041 0.002 0.0044
Brugia malayi TAR-binding protein 0.0064 0.0084 0.0177
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0133 0.0277 0.0602
Onchocerca volvulus 0.0156 0.034 0.1696
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.015 0.0324 0.0321
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0338 0.0848 0.1865
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0156 0.034 0.0739
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0129 0.0799
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.0398 0.0874
Echinococcus granulosus zinc finger protein 0.0052 0.005 0.0047
Loa Loa (eye worm) TK/EPH protein kinase 0.0086 0.0144 0.0318
Onchocerca volvulus 0.0205 0.0478 0.2393
Onchocerca volvulus 0.0036 0.0007 0.0017
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.008 0.0129 0.0275
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.008 0.0129 0.0631
Brugia malayi neuropeptide F receptor 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.008 0.0129 0.0283
Echinococcus granulosus nAChR subunit 0.0289 0.0711 0.0709
Schistosoma mansoni neuropeptide f receptor 76f 0.0041 0.002 0.0017
Schistosoma mansoni biogenic amine (5HT) receptor 0.0041 0.002 0.0017
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0014 0.0051
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.008 0.0129 0.0126
Loa Loa (eye worm) hypothetical protein 0.0133 0.0277 0.0609
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0097 0.0175 0.0378
Loa Loa (eye worm) hypothetical protein 0.008 0.0129 0.0283
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0044
Schistosoma mansoni DNA helicase recq1 0.005 0.0046 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0289 0.0711 0.1564
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0289 0.0711 0.0709
Schistosoma mansoni ap endonuclease 0.0037 0.0008 0.0006
Plasmodium vivax 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative 0.0745 0.1986 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.002 0.0017
Mycobacterium ulcerans hypothetical protein 0.0039 0.0013 0.0033
Onchocerca volvulus 0.0037 0.0009 0.0025
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.0398 0.0395
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0091 0.0088
Onchocerca volvulus 0.0133 0.0277 0.1381
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0062 0.008 0.0368
Loa Loa (eye worm) ctsf protein 0.0035 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.008 0.0129 0.0631
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0124 0.0607
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.008 0.0129 0.0631
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0061 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0014 0.0051
Schistosoma mansoni lipoxygenase 0.0114 0.0223 0.0221
Loa Loa (eye worm) hypothetical protein 0.0381 0.0969 0.2131
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0075 0.0115 0.0561
Echinococcus granulosus lamin dm0 0.0083 0.0136 0.0133
Echinococcus multilocularis expressed protein 0.0381 0.097 0.0967
Loa Loa (eye worm) hypothetical protein 0.0176 0.0395 0.0869
Onchocerca volvulus 0.0037 0.0009 0.0025
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0071 0.0103 0.0488
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0075 0.0459
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0375 0.0952 0.6054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0035 0.0159
Loa Loa (eye worm) jmjC domain-containing protein 0.0113 0.022 0.0484
Echinococcus granulosus snurportin 1 0.0311 0.0773 0.0771
Loa Loa (eye worm) ACC-1 protein 0.0289 0.0711 0.1564
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0041 0.002 0.0036
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.005 0.0046 0.0043
Echinococcus granulosus neuropeptide Y receptor 0.0041 0.002 0.0017
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.008 0.0129 0.0283
Echinococcus granulosus neuropeptide receptor A26 0.2453 0.6753 0.6752
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0075 0.0438
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0133 0.0277 0.0602
Onchocerca volvulus Fxna peptidase homolog 0.0039 0.0013 0.0049
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0062 0.008 0.0368
Echinococcus granulosus peptide allatostatin:somatostatin 0.0041 0.002 0.0017
Onchocerca volvulus 0.0049 0.0043 0.0201
Brugia malayi neuropeptide F receptor 0.0041 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0027
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0071 0.0103 0.0504
Schistosoma mansoni hypothetical protein 0.0037 0.0009 0.0006
Schistosoma mansoni hypothetical protein 0.0053 0.0053 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0739 0.1968 0.4327
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0289 0.0711 0.0709

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.9 uM Inhibition of Farnesyltransferase ChEMBL. 11906287
IC50 (binding) = 0.9 uM Inhibitory activity against human Farnesyltransferase ChEMBL. 9804689
IC50 (binding) = 0.9 uM Inhibition of Farnesyltransferase ChEMBL. 11906287
IC50 (binding) = 0.9 uM Inhibitory activity against human Farnesyltransferase ChEMBL. 9804689

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

2 literature references were collected for this gene.

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