Detailed information for compound 71366

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 454.57 | Formula: C26H30N8
  • H donors: 2 H acceptors: 2 LogP: 3.13 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1CCN(C=N1)Cc1ccc2c(c1)nc([nH]2)CCc1nc2c([nH]1)ccc(c2)CN1CCCN=C1
  • InChi: 1S/C26H30N8/c1-9-27-17-33(11-1)15-19-3-5-21-23(13-19)31-25(29-21)7-8-26-30-22-6-4-20(14-24(22)32-26)16-34-12-2-10-28-18-34/h3-6,13-14,17-18H,1-2,7-12,15-16H2,(H,29,31)(H,30,32)
  • InChiKey: WVSVIMTUIJRFKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0111 0.0286 0.0503
Schistosoma mansoni hypothetical protein 0.002 0.0016 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0512 0.0901
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.005 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0001 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0165 0.0448 0.0553
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0272 0.048
Onchocerca volvulus 0.0112 0.0291 0.0512
Schistosoma mansoni ap endonuclease 0.006 0.0136 0.024
Echinococcus granulosus g protein coupled receptor 0.0097 0.0246 0.0304
Schistosoma mansoni hypothetical protein 0.0053 0.0112 0.0198
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0222 0.0619 0.0765
Onchocerca volvulus 0.0325 0.0926 0.1632
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0136 0.0631
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0009
Toxoplasma gondii histone lysine methyltransferase SET1 0.011 0.0285 0.3046
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0026 0.0407
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0291 0.0825 0.102
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Loa Loa (eye worm) latrophilin receptor protein 2 0.0165 0.0448 0.0789
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0026 0.0047
Trypanosoma brucei C-14 sterol reductase, putative 0.0091 0.0226 0.0408
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0006 0.0011
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0007
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0291 0.3111
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.005 0.0088
Brugia malayi Abnormal catecholamine distribution protein 1 0.0774 0.227 0.3999
Brugia malayi AKH receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis short transient receptor potential channel 6 0.0067 0.0156 0.0156
Schistosoma mansoni vesicular amine transporter 0.0774 0.227 0.3999
Plasmodium vivax SET domain protein, putative 0.0031 0.0049 0.0489
Onchocerca volvulus 0.0051 0.0106 0.0187
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Trypanosoma brucei trypanothione reductase 0.0177 0.0484 0.0873
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0018 0.0009 0.0015
Brugia malayi Cation transporter family protein 0.0222 0.0619 0.1091
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0138 0.025
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0289 0.0509
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.0004 0.0005
Brugia malayi metabotropic glutamate receptor type 2 0.0018 0.0009 0.0015
Trypanosoma brucei C-8 sterol isomerase, putative 0.1869 0.554 1
Loa Loa (eye worm) LGC-31 protein 0.0222 0.0619 0.1091
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0077 0.0185 0.0326
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0136 0.1433
Echinococcus granulosus G protein coupled receptor 139 0.0097 0.0246 0.0304
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0011 0.0021
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0136 0.0246
Brugia malayi MH1 domain containing protein 0.0017 0.0006 0.0011
Schistosoma mansoni glutamate synthase 0.0016 0.0004 0.0007
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0026 0.0407
Brugia malayi nuclear receptor RXR 0.0017 0.0005 0.0009
Schistosoma mansoni hypothetical protein 0.1759 0.5212 0.9184
Echinococcus granulosus glycine receptor subunit alpha 1 0.0222 0.0619 0.0765
Trypanosoma cruzi squalene synthase, putative 0.0246 0.0692 0.1249
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0041 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0011 0.0036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0017 0.0236
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Mycobacterium tuberculosis Conserved protein 0.0112 0.0291 0.137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Onchocerca volvulus 0.0112 0.0291 0.0512
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0272 0.4992
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0325 0.0926 1
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0291 0.4133
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0165 0.0448 0.0448
Loa Loa (eye worm) neuropeptide F receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0016 0.0004 0.0007
Brugia malayi ecdysteroid receptor 0.0032 0.005 0.0088
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0097 0.0246 0.0434
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0045 0.009 0.0158
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Schistosoma mansoni hypothetical protein 0.0803 0.2356 0.4151
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0403 0.116 0.5519
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0272 0.387
Loa Loa (eye worm) RNA binding protein 0.0074 0.0176 0.0311
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0173 0.0213
Echinococcus granulosus FTZ F1 alpha 0.0032 0.005 0.0062
Echinococcus multilocularis musashi 0.0086 0.0212 0.0212
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0049 0.0049
Schistosoma mansoni amine GPCR 0.0097 0.0246 0.0434
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0021 0.0017 0.003
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0013 0.0022
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0725 0.0725
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0061 0.0138 0.0138
Mycobacterium tuberculosis Conserved protein 0.0112 0.0291 0.137
Brugia malayi MH1 domain containing protein 0.0017 0.0006 0.0011
Entamoeba histolytica hypothetical protein 0.0036 0.0062 0.1082
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1869 0.554 0.9761
Echinococcus multilocularis neuropeptide receptor 0.0097 0.0246 0.0246
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0026 0.0104
Schistosoma mansoni hypothetical protein 0.0077 0.0185 0.0326
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0034 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.005 0.0088
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0096 0.0096
Trypanosoma cruzi squalene synthase, putative 0.0246 0.0692 0.1249
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0473 0.6718
Onchocerca volvulus 0.0031 0.0049 0.0086
Schistosoma mansoni nuclear hormone receptor 0.0032 0.005 0.0088
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0272 0.4992
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0016 0.0028
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0026 0.0407
Brugia malayi Dopamine receptor protein 2 0.0097 0.0246 0.0434
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0021 0.0017 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Plasmodium falciparum glutathione reductase 0.0061 0.0138 0.1458
Trichomonas vaginalis apoptosis inducing factor, putative 0.0016 0.0004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0086 0.0212 0.0374
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0138 0.2501
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0136 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0194 0.0535 0.0942
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0005 0.001
Echinococcus granulosus neuropeptide receptor A26 0.0097 0.0246 0.0304
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.005 0.005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0222 0.0619 0.1091
Schistosoma mansoni adenoreceptor 0.0097 0.0246 0.0434
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0106 0.0187
Echinococcus multilocularis aryl hydrocarbon receptor 0.0016 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Echinococcus granulosus synaptic vesicular amine transporter 0.0774 0.227 0.2804
Schistosoma mansoni hypothetical protein 0.1759 0.5212 0.9184
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0016 0.0004 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0325 0.0926 0.1632
Leishmania major protein kinase, putative 0.0021 0.0018 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0139 0.0139
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0034 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Toxoplasma gondii thioredoxin reductase 0.0177 0.0484 0.52
Plasmodium vivax glutathione reductase, putative 0.0177 0.0484 0.52
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0222 0.0619 0.0619
Loa Loa (eye worm) thioredoxin reductase 0.0177 0.0484 0.0852
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0026 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0026 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0026 0.0045
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0003 0.0003
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0272 0.0492
Echinococcus multilocularis glycine receptor subunit beta 0.0222 0.0619 0.0619
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Schistosoma mansoni hypothetical protein 0.0165 0.0448 0.0789
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.005 0.005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) glutathione reductase 0.0177 0.0484 0.0852
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Schistosoma mansoni disulfide oxidoreductase 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0609 0.1776 0.3128
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0097 0.0246 0.0434
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0512 0.0901
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0136 0.2458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.0512 0.0901
Loa Loa (eye worm) hypothetical protein 0.063 0.1839 0.3241
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.0004 0.0007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0061 0.0138 0.0171
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0064 0.0145 0.018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0196 0.0542 0.7699
Echinococcus granulosus dnaJ subfamily B 0.0803 0.2356 0.2911
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0042 0.0052
Schistosoma mansoni alpha-1 adrenergic receptor 0.0097 0.0246 0.0434
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.0469 0.0827
Echinococcus multilocularis nAChR subunit 0.0111 0.0286 0.0286
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0097 0.0246 0.0434
Leishmania major trypanothione reductase 0.0177 0.0484 0.0873
Schistosoma mansoni neuropeptide receptor 0.0097 0.0246 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Onchocerca volvulus 0.0056 0.0124 0.0218
Echinococcus granulosus short transient receptor potential channel 6 0.0067 0.0156 0.0193
Echinococcus multilocularis cpg binding protein 0.0061 0.0139 0.0139
Brugia malayi hypothetical protein 0.0036 0.0062 0.0109
Schistosoma mansoni metabotropic glutamate receptor 0.0018 0.0009 0.0015
Echinococcus multilocularis geminin 0.1759 0.5212 0.5212
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0013 0.0022
Schistosoma mansoni neuropeptide F-like receptor 0.0097 0.0246 0.0434
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0138 0.2501
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0013 0.0023
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0176 0.0311
Brugia malayi Latrophilin receptor protein 2 0.0165 0.0448 0.0789
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Onchocerca volvulus 0.0097 0.0246 0.0434
Brugia malayi RNA binding protein 0.0074 0.0176 0.0311
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.005 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0097 0.0246 0.0246
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.0004 0.0005
Echinococcus granulosus neuropeptide receptor 0.0097 0.0246 0.0304
Echinococcus multilocularis NMDA receptor 0.0064 0.0145 0.0145
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0078 0.1101
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0061 0.0138 0.025
Schistosoma mansoni glutamate receptor kainate 0.0172 0.0469 0.0827
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0316 0.0557
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0026 0.0407
Brugia malayi putative neuropeptide receptor NPR1 0.0097 0.0246 0.0434
Loa Loa (eye worm) ACC-1 protein 0.0222 0.0619 0.1091
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0016 0.0004 0.0005
Echinococcus granulosus sex peptide receptor 0.0097 0.0246 0.0304
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0011 0.0081
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0097 0.0246 0.0434
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.003
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0222 0.0619 0.1091
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0325 0.0926 1
Schistosoma mansoni inositol monophosphatase 0.0196 0.0542 0.0955
Echinococcus multilocularis zinc finger protein 0.0022 0.0022 0.0022
Schistosoma mansoni opsin-like receptor 0.0097 0.0246 0.0434
Onchocerca volvulus 0.0097 0.0246 0.0434
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0211 0.0587 0.0587
Brugia malayi hypothetical protein 0.0112 0.0289 0.0508
Echinococcus granulosus neuropeptide FF receptor 2 0.0097 0.0246 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0006 0.0007
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0021 0.0017 0.0239
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus multilocularis glutamate receptor NMDA 0.0092 0.0231 0.0231
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.0004 0.0007
Echinococcus multilocularis Squalene phytoene synthase 0.0077 0.0185 0.0185
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0026 0.0407
Echinococcus granulosus hypothetical protein 0.0097 0.0246 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0026 0.0104
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0013 0.0023
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0072 0.0072
Schistosoma mansoni gabp alpha 0.0073 0.0173 0.0304
Plasmodium falciparum thioredoxin reductase 0.0061 0.0138 0.1458
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0011 0.0013
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0097 0.0246 0.0246
Schistosoma mansoni neuropeptide receptor 0.0097 0.0246 0.0434
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.005 0.005
Schistosoma mansoni bromodomain containing protein 0.0065 0.015 0.0264
Onchocerca volvulus 0.0721 0.2109 0.3716
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0013 0.0013
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.025 0.0704 0.124
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0097 0.0246 0.0434
Loa Loa (eye worm) glutamate receptor 2 0.0172 0.0469 0.0826
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0026 0.0047
Echinococcus granulosus glycine receptor subunit alpha 1 0.0222 0.0619 0.0765
Schistosoma mansoni neuropeptide receptor 0.0097 0.0246 0.0434
Echinococcus granulosus glutamate receptor subunit protein glur 0.0064 0.0145 0.018
Mycobacterium ulcerans monophosphatase CysQ 0.0021 0.0017 0.0239
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0013 0.0023
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0136 0.024
Schistosoma mansoni glutamate receptor NMDA 0.0365 0.1047 0.1845
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.006 0.0074
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0111 0.0286 0.0504
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0005 0.0009
Onchocerca volvulus 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Echinococcus granulosus metabotropic glutamate receptor 5 0.0018 0.0009 0.001
Brugia malayi phosphofructokinase 0.0106 0.0272 0.048
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0005 0.0009
Echinococcus multilocularis lamin b receptor 0.0091 0.0226 0.0226
Schistosoma mansoni nAChR subunit 0.0112 0.0289 0.0509
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0127 0.0127
Loa Loa (eye worm) MBCTL1 0.0058 0.0127 0.0224
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0291 0.4133
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0026 0.0237
Onchocerca volvulus 0.0222 0.0619 0.1091
Trichomonas vaginalis mercuric reductase, putative 0.0061 0.0138 0.1965
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0034 0.006
Schistosoma mansoni transient receptor potential channel 4 0.01 0.0254 0.0448
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0026 0.0407
Loa Loa (eye worm) hypothetical protein 0.0062 0.0141 0.0248
Brugia malayi Guanylyl cyclase protein 23 0.0018 0.0009 0.0015
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0021 0.0017 0.0239
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0325 0.0926 0.1632
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Echinococcus multilocularis nmda type glutamate receptor 0.011 0.0284 0.0284
Schistosoma mansoni Lamin B receptor (ERG24) 0.0091 0.0226 0.0398
Schistosoma mansoni myo inositol monophosphatase 0.0021 0.0017 0.003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0111 0.0286 0.0503
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0097 0.0246 0.0434
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0774 0.227 0.3999
Brugia malayi RE15519p 0.0097 0.0246 0.0434
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0325 0.0926 0.0926
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0097 0.0246 0.0246
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0097 0.0246 0.0246
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0097 0.0246 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0136 0.0246
Loa Loa (eye worm) ACC-1 protein 0.0222 0.0619 0.1091
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0026 0.0407
Echinococcus multilocularis thioredoxin glutathione reductase 0.0177 0.0485 0.0485
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2723 0.8093 0.8093
Schistosoma mansoni lipoxygenase 0.0022 0.002 0.0035
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0001 0.0001
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0013 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0097 0.0246 0.0304
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0011 0.0021
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0721 0.2109 0.3716
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0222 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0272 0.2102
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0083 0.0146
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0325 0.0926 0.1632
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.005 0.0088
Brugia malayi Bromodomain containing protein 0.0076 0.0184 0.0324
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0034 0.0042
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0165 0.0448 0.0789
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.005 0.005
Leishmania major hypothetical protein, conserved 0.0112 0.0291 0.0525
Echinococcus multilocularis g protein coupled receptor 0.0097 0.0246 0.0246
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0026 0.0407
Schistosoma mansoni rab6-interacting 0.0022 0.002 0.0035
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0176 0.0311
Echinococcus multilocularis serotonin transporter 0.1914 0.5675 0.5675
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0021 0.0017 0.003
Brugia malayi Receptor family ligand binding region containing protein 0.0018 0.0009 0.0015
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0272 0.048
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.017 0.017
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0097 0.0246 0.0434
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.005 0.0088
Echinococcus granulosus neuropeptide receptor 0.0254 0.0714 0.0882
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0291 0.0513
Brugia malayi hypoxia-induced factor 1 0.0179 0.049 0.0863
Schistosoma mansoni hypothetical protein 0.0036 0.0062 0.011
Echinococcus multilocularis glutamate receptor 2 0.0172 0.0469 0.0469
Brugia malayi CXXC zinc finger family protein 0.0056 0.0124 0.0218
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0011 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Loa Loa (eye worm) inositol-1 0.0196 0.0542 0.0954
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0325 0.0926 0.1632
Toxoplasma gondii NADPH-glutathione reductase 0.0061 0.0138 0.1458
Onchocerca volvulus 0.0111 0.0286 0.0503
Echinococcus multilocularis RUN 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Onchocerca volvulus 0.0112 0.0289 0.0508
Leishmania major cytochrome p450-like protein 0.0024 0.0026 0.0047
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0006 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.0522 0.0522
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0026 0.0104
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0021 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0158 0.0428 0.0754
Loa Loa (eye worm) hypothetical protein 0.0257 0.0725 0.1277
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0196 0.0542 0.0978
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.002 0.017
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1869 0.554 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0272 0.0492
Schistosoma mansoni hypothetical protein 0.0064 0.0145 0.0256
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0097 0.0246 0.0304
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0291 0.0525
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0291 0.137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.005 0.0088
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0034 0.0034
Echinococcus granulosus nAChR subunit 0.0222 0.0619 0.0765
Entamoeba histolytica hypothetical protein 0.0111 0.0286 0.524
Echinococcus granulosus nmda type glutamate receptor 0.011 0.0284 0.0351
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0007 0.0012
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0365 0.1047 0.1047
Schistosoma mansoni smad 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0013 0.0161
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.005 0.0062
Echinococcus granulosus glycine receptor subunit beta 0.0222 0.0619 0.0765
Onchocerca volvulus 0.0097 0.0246 0.0434
Brugia malayi Metabotropic glutamate receptor precursor. 0.0018 0.0009 0.0015
Onchocerca volvulus 0.0111 0.0286 0.0503
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0041 0.0402
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0272 0.4992
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0097 0.0246 0.0434
Loa Loa (eye worm) solute carrier family 6 member 4 0.1914 0.5675 1
Schistosoma mansoni metabotropic glutamate receptor 0.0018 0.0009 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0026 0.0104
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0016 0.0002 0.0003
Mycobacterium ulcerans monophosphatase 0.0021 0.0017 0.0239
Echinococcus multilocularis g protein coupled receptor 0.0097 0.0246 0.0246
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0013 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.0587 0.1034
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Trypanosoma cruzi C-14 sterol reductase, putative 0.0091 0.0226 0.0408
Schistosoma mansoni microtubule-associated protein tau 0.1584 0.4688 0.826
Echinococcus multilocularis serotonin receptor 0.0097 0.0246 0.0246
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0106 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Brugia malayi steroid hormone receptor 0.0032 0.005 0.0088
Echinococcus multilocularis G-protein coupled receptor, putative 0.0097 0.0246 0.0246
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.005 0.005
Brugia malayi vesicular acetylcholine transporter unc-17 0.0909 0.2673 0.4709
Echinococcus granulosus metabotropic glutamate receptor 2 0.0018 0.0009 0.001
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.005 0.0088
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0034 0.0061
Onchocerca volvulus 0.0097 0.0246 0.0434
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0018 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0319 0.091 0.1603
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Echinococcus granulosus glutamate synthase 0.0016 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0165 0.0448 0.0789
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0041 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0026 0.0104
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0105 0.0268 0.0472
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0016 0.0004 0.0007
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0291 0.137
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.005 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Echinococcus granulosus intermediate filament protein 0.0086 0.0212 0.0262
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.005 0.0062
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0325 0.0926 0.1145
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0003 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0512 0.0632
Echinococcus multilocularis g-protein coupled receptor 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0097 0.0246 0.0246
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0016 0.0004 0.0004
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0061 0.0138 0.1458
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0013 0.0023
Brugia malayi Cation transporter family protein 0.0721 0.2109 0.3716
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0325 0.0926 0.1632
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0176 0.0311
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0211 0.0587 0.0725
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) hypothetical protein 0.0084 0.0208 0.0366
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0176 0.048 0.2273
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0403 0.116 0.5519
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0106 0.0187
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0222 0.0619 0.1091
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.003
Brugia malayi Muscleblind-like protein 0.0158 0.0428 0.0754
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0026 0.0198
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0026 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0097 0.0246 0.0434
Schistosoma mansoni single-minded 0.0058 0.0128 0.0226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0131
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0131
Echinococcus multilocularis GPCR, family 2 0.0165 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0521 0.1511 0.2662
Echinococcus multilocularis glycine receptor subunit beta 0.0222 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Schistosoma mansoni glutamate synthase 0.0016 0.0004 0.0007
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0291 0.137
Brugia malayi Inositol-1 0.0196 0.0542 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.048
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0325 0.0926 0.0926
Echinococcus granulosus orexin receptor type 2 0.0097 0.0246 0.0304
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0222 0.0619 0.1091
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0017 0.0236
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0016 0.0004 0.0029
Trypanosoma cruzi extracellular receptor, putative 0.0018 0.0009 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0097 0.0246 0.0434
Brugia malayi excitatory GABA receptor EXP-1A 0.0222 0.0619 0.1091
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0026 0.0104
Toxoplasma gondii exonuclease III APE 0.006 0.0136 0.1433
Echinococcus granulosus smad 0.0017 0.0006 0.0007
Plasmodium vivax thioredoxin reductase, putative 0.0177 0.0484 0.52
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0061 0.0138 0.1492
Echinococcus granulosus neuropeptide s receptor 0.0097 0.0246 0.0304
Schistosoma mansoni Smad4 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.005 0.0088
Brugia malayi 6-phosphofructokinase 0.0106 0.0273 0.048
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0176 0.0311
Echinococcus granulosus sodium and chloride dependent glycine 0.0325 0.0926 0.1145
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0291 0.0512
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0004 0.0007
Loa Loa (eye worm) doublecortin family protein 0.0022 0.002 0.0034
Giardia lamblia GTOR 0.0019 0.0013 0.0643
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0045 0.009 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.005 0.0088
Mycobacterium tuberculosis Probable dehydrogenase 0.0403 0.116 0.5519
Echinococcus granulosus transient receptor potential gamma protein 0.01 0.0254 0.0314
Brugia malayi cytochrome P450 0.0024 0.0026 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0011 0.0011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.005 0.005
Plasmodium falciparum thioredoxin reductase 0.0177 0.0484 0.52
Brugia malayi hypothetical protein 0.0022 0.002 0.0034
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0097 0.0246 0.0434
Brugia malayi Bromodomain containing protein 0.0037 0.0067 0.0118
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0291 0.137
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0272 0.048
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Brugia malayi hypothetical protein 0.0112 0.0289 0.0508
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Echinococcus multilocularis receptor type guanylyl cyclase 0.0018 0.0009 0.0008
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0111 0.0286 0.0504
Toxoplasma gondii ABC1 family protein 0.0112 0.0291 0.3111
Echinococcus multilocularis nAChR subunit 0.0222 0.0619 0.0619
Brugia malayi Fli-1 protein 0.0221 0.0615 0.1083
Schistosoma mansoni intermediate filament proteins 0.0086 0.0212 0.0374
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Echinococcus granulosus glycine receptor subunit beta 0.0222 0.0619 0.0765
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Schistosoma mansoni inositol monophosphatase 0.0196 0.0542 0.0955
Echinococcus granulosus glutamate receptor 2 0.0126 0.0332 0.041
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0041 0.044
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0127 0.0224
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.0522 0.0645
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0026 0.0045
Echinococcus granulosus serotonin transporter 0.1914 0.5675 0.7013
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0016 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Schistosoma mansoni tyrosine kinase 0.0018 0.0009 0.0015
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0016 0.0004 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0291 0.4133
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0291 0.4133
Brugia malayi ORL1-like opioid receptor 0.0097 0.0246 0.0434
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.0522 0.0645
Schistosoma mansoni loxhd1 0.0022 0.002 0.0035
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0291 0.137
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0222 0.0619 0.0619
Brugia malayi hypothetical protein 0.0018 0.0009 0.0015
Echinococcus granulosus biogenic amine 5HT receptor 0.0097 0.0246 0.0304
Loa Loa (eye worm) hypothetical protein 0.1813 0.5373 0.9467
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Onchocerca volvulus 0.0016 0.0004 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0026 0.0104
Mycobacterium tuberculosis Monophosphatase CysQ 0.0021 0.0017 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0028
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0031 0.0439
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0009
Echinococcus granulosus RUN 0.0022 0.002 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Schistosoma mansoni cpg binding protein 0.0056 0.0124 0.0218
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0041 0.0065
Echinococcus granulosus lamin 0.0086 0.0212 0.0262
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0291 0.5336
Schistosoma mansoni amine GPCR 0.0097 0.0246 0.0434
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0062 0.0062
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0061 0.0138 0.2501
Echinococcus multilocularis muscleblind protein 1 0.0158 0.0428 0.0428
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0291 0.0525
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0176 0.0176
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0031 0.0439
Echinococcus granulosus glutamate NMDA receptor subunit 0.0365 0.1047 0.1294
Schistosoma mansoni opsin-like receptor 0.0097 0.0246 0.0434
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0026 0.0407
Schistosoma mansoni lipoxygenase 0.006 0.0135 0.0238
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0291 0.0825 0.0825
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0011 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.2723 0.8093 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0041 0.0402
Schistosoma mansoni hypothetical protein 0.0356 0.1019 0.1795
Onchocerca volvulus 0.0097 0.0246 0.0434
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0097 0.0246 0.0434
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0026 0.0407
Trichomonas vaginalis inositol monophosphatase, putative 0.0196 0.0542 0.7699
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0112 0.0289 0.0289
Echinococcus multilocularis Smad4 0.0017 0.0006 0.0006
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0222 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0242
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0111 0.0286 0.0503
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0016 0.0004 0.0004
Echinococcus granulosus fmrfamide receptor 0.0097 0.0246 0.0304
Loa Loa (eye worm) hypothetical protein 0.0165 0.0448 0.0789
Echinococcus granulosus cpg binding protein 0.0061 0.0139 0.0172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.005 0.0088
Echinococcus granulosus Smad4 0.0017 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0096 0.0169
Onchocerca volvulus 0.0097 0.0246 0.0434
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.005 0.0062
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0289 0.0508
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0196 0.0542 0.7699
Brugia malayi Dopamine receptor protein 1 0.0097 0.0246 0.0434
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.019 0.0522 0.0645
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0289 0.0508
Schistosoma mansoni amine GPCR 0.0097 0.0246 0.0434
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0106 0.0106
Mycobacterium ulcerans monophosphatase CysQ 0.0021 0.0017 0.0239
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Schistosoma mansoni biogenic amine receptor 0.0097 0.0246 0.0434
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0104 0.0267 0.047
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0018 0.0009 0.0015
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0026 0.0407
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0004 0.0007
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0061 0.0138 0.1458
Onchocerca volvulus 0.0086 0.0212 0.0374
Onchocerca volvulus 0.0112 0.0289 0.0508
Onchocerca volvulus 0.0097 0.0246 0.0434
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.005 0.0088
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0013 0.0094
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0272 0.0473
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0011 0.0021
Echinococcus granulosus thioredoxin glutathione reductase 0.0177 0.0485 0.0599
Onchocerca volvulus 0.0325 0.0926 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Onchocerca volvulus 0.0097 0.0246 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.005 0.0088
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0291 0.0513
Schistosoma mansoni cytochrome P450 0.0024 0.0026 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0026 0.0104
Brugia malayi hypothetical protein 0.0194 0.0535 0.0942
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.0004 0.0007
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.0522 0.0522
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0325 0.0926 0.1145
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0018 0.0009 0.0015
Onchocerca volvulus 0.0022 0.002 0.0034
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0112 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0041 0.0079 0.014
Schistosoma mansoni sodium-dependent amino acid transporter 0.0325 0.0926 0.1632
Brugia malayi hypothetical protein 0.0112 0.0289 0.0508
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0061 0.0138 0.2501
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0108 0.019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0061 0.0138 0.2501
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0013 0.0022
Echinococcus granulosus inositol monophosphatase 0.0021 0.0017 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0106 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Brugia malayi larval opioid receptor 0.0097 0.0246 0.0434
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0006 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Schistosoma mansoni hypothetical protein 0.0055 0.0119 0.021
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Echinococcus multilocularis smad 0.0017 0.0006 0.0006
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0026 0.0032
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0448 0.1295 0.6161
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0041 0.0079 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0062 0.011
Leishmania major squalene synthase, putative 0.0246 0.0692 0.1249
Schistosoma mansoni tyrosine kinase 0.0018 0.0009 0.0015
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0289 0.0509
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0049 0.0087
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.005 0.0088
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0136 0.024
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.01 0.0254 0.0448
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0011 0.0011
Echinococcus multilocularis tyrosine kinase 0.0018 0.0009 0.0008
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0097 0.0246 0.0434
Echinococcus granulosus vesicular acetylcholine transporter 0.0909 0.2673 0.3303
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Loa Loa (eye worm) fli-1 protein 0.0221 0.0615 0.1083
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0006 0.0006
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0196 0.0542 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0018 0.0009 0.0008
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.005 0.0088
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.002 0.0024
Brugia malayi Ets-domain containing protein 0.0073 0.0173 0.0304
Loa Loa (eye worm) hypothetical protein 0.1914 0.5675 1
Brugia malayi Cytochrome P450 family protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0011 0.0011
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0031 0.0031
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0021 0.0017 0.0128
Brugia malayi hypothetical protein 0.0022 0.002 0.0034
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0026 0.0047
Echinococcus granulosus glycine receptor subunit alpha 1 0.0222 0.0619 0.0765
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.005 0.0088
Echinococcus multilocularis inositol monophosphatase 1 0.0196 0.0542 0.0542
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0403 0.116 0.8961
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Echinococcus granulosus tyrosine kinase 0.0018 0.0009 0.001
Echinococcus multilocularis sex peptide receptor 0.0097 0.0246 0.0246
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.0469 0.0827
Brugia malayi mbt repeat family protein 0.0051 0.0106 0.0187
Schistosoma mansoni growth hormone secretagogue receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis serotonin receptor 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0356 0.1019 0.1795
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Onchocerca volvulus 0.0097 0.0246 0.0434
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0099 0.0099
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0139 0.0172
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0007 0.0028
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0717 0.2099 1
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0011 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Schistosoma mansoni cpg binding protein 0.0061 0.0139 0.0245
Schistosoma mansoni thyroid hormone receptor 0.0032 0.005 0.0088
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0016 0.0004 0.0005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0322 0.0917 0.1616
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0016 0.0004 0.0005
Schistosoma mansoni biogenic amine receptor 0.0097 0.0246 0.0434
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0026 0.0407
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.025 0.0704 0.124
Schistosoma mansoni cpg binding protein 0.0061 0.0139 0.0245
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0049 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Onchocerca volvulus Putative nachr subunit 0.0291 0.0825 0.1454
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0064 0.0145 0.0145
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.005 0.0088
Mycobacterium ulcerans hypothetical protein 0.0112 0.0291 0.5336
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0064 0.0145 0.0145
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0005 0.0009
Echinococcus granulosus single minded 2 0.0047 0.0095 0.0118
Echinococcus granulosus tachykinin peptides receptor 99D 0.0097 0.0246 0.0304
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0026 0.0104
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0106 0.0187
Mycobacterium leprae putative cytochrome p450 0.0024 0.0026 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Schistosoma mansoni sulfide quinone reductase 0.0016 0.0004 0.0007
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0291 0.0512
Echinococcus multilocularis short transient receptor potential channel 6 0.0067 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.0034
Onchocerca volvulus 0.0097 0.0246 0.0434
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.0002 0.0002
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0222 0.0619 0.0765
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0011 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0291 0.0825 0.102
Schistosoma mansoni transient receptor potential channel 0.01 0.0254 0.0448
Mycobacterium ulcerans phytoene synthase, CrtB 0.0077 0.0185 0.3365
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0093 0.0164
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0079 0.0098
Toxoplasma gondii hypothetical protein 0.0021 0.0017 0.0139
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0165 0.0448 0.0789
Loa Loa (eye worm) hypothetical protein 0.0058 0.0127 0.0224
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0138 0.025
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0222 0.0619 0.0765
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Cytochrome P450 family protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.0097 0.0246 0.0434
Echinococcus granulosus neuropeptide Y receptor 0.0097 0.0246 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0026 0.0104
Onchocerca volvulus 0.0097 0.0246 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Leishmania major extracellular receptor, putative 0.0018 0.0009 0.0015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0521 0.1511 0.2662
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0026 0.0407
Loa Loa (eye worm) hypothetical protein 0.0069 0.0162 0.0285
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Schistosoma mansoni glutamate receptor kainate 0.0172 0.0469 0.0827
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0026 0.0047
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0026 0.0104
Mycobacterium leprae Probable lipase LipE 0.0112 0.0291 0.2245
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1914 0.5675 1
Echinococcus granulosus somatostatin receptor 0.0097 0.0246 0.0304
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0136 0.1932
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0021 0.0017 0.003
Echinococcus granulosus dro:myosuppressin receptor 0.0097 0.0246 0.0304
Entamoeba histolytica hypothetical protein 0.0026 0.0034 0.0558
Brugia malayi TAR-binding protein 0.0074 0.0176 0.0311
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0061 0.0138 0.025
Leishmania major NADH dehydrogenase, putative 0.0016 0.0004 0.0007
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0005 0.0009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.005 0.0088
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0003 0.0004
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0106 0.0187
Echinococcus granulosus 7tm_1 domain containing protein 0.0097 0.0246 0.0304
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0072 0.0127
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0104 0.0267 0.047
Loa Loa (eye worm) programmed cell death 8 0.0016 0.0004 0.0007
Schistosoma mansoni ATP-binding cassette transporter 0.0172 0.0469 0.0827
Echinococcus granulosus GPCR family 2 0.0165 0.0448 0.0553
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0112 0.0289 0.0508
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.005 0.0062
Loa Loa (eye worm) beta-lactamase 0.0112 0.0291 0.0512
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0041 0.044
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0021 0.0017 0.003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Brugia malayi Receptor family ligand binding region containing protein 0.0018 0.0009 0.0015
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0005 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0699 0.1231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0112 0.0198
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0013 0.0023
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0291 0.2245
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.0004 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0096 0.0119
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0222 0.0619 0.1091
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0325 0.0926 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0049 0.0489
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0007
Echinococcus granulosus 7TM GPCR rhodopsin 0.0097 0.0246 0.0304
Brugia malayi glutathione reductase 0.0177 0.0484 0.0852
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0017 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0403 0.116 0.5519
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0325 0.0926 0.1632
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0111 0.0286 0.0503
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0026 0.0104
Onchocerca volvulus 0.0097 0.0246 0.0434
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0222 0.0619 0.1091
Trichomonas vaginalis glutathione reductase, putative 0.0061 0.0138 0.1965
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0013 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0356 0.1019 0.1795
Onchocerca volvulus 0.0112 0.0289 0.0508
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0013 0.0161
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0222 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.031 0.0881 0.1552
Schistosoma mansoni protein kinase 0.0018 0.0009 0.0015
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0061 0.0138 0.025
Leishmania major myo-inositol-1 phosphatase, putative 0.0021 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.0721 0.2109 0.3716
Schistosoma mansoni sulfide quinone reductase 0.0016 0.0004 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus granulosus glutamate receptor 2 0.019 0.0522 0.0645
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0097 0.0246 0.0304
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0097 0.0246 0.0246
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0721 0.2109 0.3716
Mycobacterium leprae Probable monophosphatase 0.0021 0.0017 0.0128
Onchocerca volvulus Neuropeptide F receptor homolog 0.0097 0.0246 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0473 0.6718
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0013 0.0023
Giardia lamblia Hypothetical protein 0.0021 0.0017 0.0956
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Echinococcus granulosus short transient receptor potential channel 6 0.0067 0.0156 0.0192
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0403 0.116 0.5519
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1914 0.5675 1
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0112 0.0289 0.0508
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0176 0.0311
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0196 0.0542 0.0978
Echinococcus granulosus peptide allatostatin:somatostatin 0.0097 0.0246 0.0304
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0212 0.0374
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0176 0.0311
Echinococcus granulosus geminin 0.1759 0.5212 0.6441
Schistosoma mansoni thyroid hormone receptor 0.0032 0.005 0.0088
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0112 0.0289 0.0289
Onchocerca volvulus 0.0097 0.0246 0.0434
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.0004 0.0053
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0006 0.0011
Brugia malayi G-protein coupled receptor 0.0097 0.0246 0.0434
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0011 0.0081
Treponema pallidum NADH oxidase 0.0061 0.0138 0.0237
Echinococcus granulosus alpha 1A adrenergic receptor 0.0097 0.0246 0.0304
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0136 0.1932
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0446 0.0786
Echinococcus multilocularis glutamate receptor 2 0.0126 0.0332 0.0332
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0026 0.0047
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.0522 0.0522
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0512 0.0632
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0009 0.0015
Brugia malayi hypothetical protein 0.0325 0.0926 0.1632
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.0004 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0009
Brugia malayi beta-lactamase family protein 0.0112 0.0291 0.0512
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0064 0.0145 0.018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0097 0.0246 0.0246
Schistosoma mansoni lamin 0.0086 0.0212 0.0374
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0061 0.0138 0.1458
Brugia malayi Serotonin receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0135 0.0135
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0097 0.0246 0.0434
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0196 0.0542 0.583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0097 0.0246 0.0304
Schistosoma mansoni neuropeptide f receptor 76f 0.0097 0.0246 0.0434
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.0004 0.0053
Schistosoma mansoni neuropeptide F-like receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis lamin dm0 0.0086 0.0212 0.0212
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0222 0.0619 0.0619
Echinococcus granulosus tar DNA binding protein 0.0074 0.0176 0.0218
Mycobacterium tuberculosis Probable monophosphatase 0.0021 0.0017 0.0061
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0013 0.0023
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypoxia-induced factor 1 0.0179 0.049 0.0863
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0512 0.0511
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0177 0.0484 0.2289
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Schistosoma mansoni sodium/chloride dependent transporter 0.0325 0.0926 0.1632
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0176 0.0311
Brugia malayi beta-lactamase 0.0112 0.0291 0.0512
Brugia malayi 6-phosphofructokinase 0.0106 0.0272 0.048
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0018 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Echinococcus multilocularis g protein coupled receptor 0.0097 0.0246 0.0246
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0325 0.0926 0.1145
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Treponema pallidum sodium- and chloride- dependent transporter 0.1914 0.5675 1
Echinococcus multilocularis synaptic vesicular amine transporter 0.0774 0.227 0.2269
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0272 0.387
Brugia malayi hypothetical protein 0.0257 0.0725 0.1277
Trypanosoma cruzi trypanothione reductase, putative 0.0177 0.0484 0.0873
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0026 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Mycobacterium tuberculosis Probable oxidoreductase 0.0448 0.1295 0.6161
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0136 0.2458
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.0236 0.0291
Brugia malayi PHD-finger family protein 0.0028 0.0038 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.005 0.0062
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0222 0.0619 0.0619
Echinococcus multilocularis transient receptor potential gamma protein 0.01 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.1813 0.5373 0.9467
Echinococcus granulosus g protein coupled receptor 0.0097 0.0246 0.0304
Brugia malayi Thioredoxin reductase 0.0177 0.0484 0.0852
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.005 0.0088
Schistosoma mansoni vesicular acetylcholine transporter 0.0909 0.2673 0.4709
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0064 0.0145 0.0145
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.005 0.0088
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0047 0.0096 0.0169
Onchocerca volvulus 0.0097 0.0246 0.0434
Schistosoma mansoni amine GPCR 0.0097 0.0246 0.0434
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0013 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.005 0.0062
Schistosoma mansoni biogenic amine receptor 0.0097 0.0246 0.0434
Echinococcus multilocularis dro:myosuppressin receptor 0.0097 0.0246 0.0246
Plasmodium falciparum amino acid transporter, putative 0.0325 0.0926 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0136 0.1433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Schistosoma mansoni hypothetical protein 0.0165 0.0448 0.0789
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0112 0.0289 0.0508
Onchocerca volvulus 0.1914 0.5675 1
Onchocerca volvulus 0.0032 0.005 0.0088
Schistosoma mansoni neuropeptide receptor 0.0254 0.0714 0.1258
Brugia malayi Tachykinin-like peptides receptor 99D 0.0097 0.0246 0.0434
Brugia malayi neuropeptide F receptor 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0005 0.0005
Echinococcus multilocularis 0.0024 0.0026 0.0026
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.005 0.0088
Brugia malayi glutamate synthase 0.0016 0.0004 0.0007
Echinococcus granulosus inositol monophosphatase 1 0.0196 0.0542 0.0669
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Onchocerca volvulus 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0158 0.0428 0.0754
Brugia malayi putative neuropeptide receptor 0.0097 0.0246 0.0434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0099 0.0174
Echinococcus granulosus lamin b receptor 0.0091 0.0226 0.0279
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0005 0.0009
Leishmania major hypothetical protein, conserved 0.0077 0.0185 0.0334
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0138 0.025
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0291 0.0291
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Schistosoma mansoni ap endonuclease 0.006 0.0136 0.024
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0097 0.0246 0.0434
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0061 0.0138 0.0642
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0135 0.0167
Echinococcus multilocularis nmda type glutamate receptor 0.0156 0.0421 0.0421
Brugia malayi hypothetical protein 0.0112 0.0289 0.0508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.005 0.0088
Echinococcus multilocularis glutamate receptor 2 0.019 0.0522 0.0522
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0136 0.0233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0097 0.0246 0.0246
Chlamydia trachomatis thioredoxin reductase 0.0016 0.0004 0.004
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0083 0.1472
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0196 0.0542 0.0978
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0165 0.0448 0.0448
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0291 0.137
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0026 0.0407
Brugia malayi Cation transporter family protein 0.0222 0.0619 0.1091
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0291 0.0359
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.0004 0.0053
Schistosoma mansoni pap-inositol-14-phosphatase 0.0021 0.0017 0.003
Schistosoma mansoni ets-related 0.0221 0.0615 0.1083
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0031 0.0055
Loa Loa (eye worm) acetylcholine receptor protein 0.0112 0.0289 0.0508
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0026 0.0407
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0013 0.0022
Brugia malayi Glutamate receptor 2 precursor 0.0172 0.0469 0.0826
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0016 0.0004 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0254 0.0714 0.0714
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.005 0.0088
Schistosoma mansoni glutamate receptor kainate 0.0172 0.0469 0.0827
Brugia malayi sulfakinin receptor protein 0.0097 0.0246 0.0434
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0272 0.1281
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.017 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0112 0.0289 0.0357
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0325 0.0926 0.1632
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0111 0.0286 0.0503
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0138 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0196 0.0542 0.0978
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0021 0.0017 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0291 0.0825 0.0825
Brugia malayi hypothetical protein 0.0017 0.0005 0.0009
Brugia malayi neuropeptide F receptor 0.0097 0.0246 0.0434
Schistosoma mansoni opsin-like receptor 0.0097 0.0246 0.0434
Trypanosoma brucei squalene synthase, putative 0.0246 0.0692 0.1249
Loa Loa (eye worm) hypothetical protein 0.0077 0.0185 0.0326
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.005 0.005
Plasmodium falciparum glutathione reductase 0.0177 0.0484 0.52
Brugia malayi beta-lactamase family protein 0.0112 0.0291 0.0512
Trypanosoma cruzi C-14 sterol reductase, putative 0.0091 0.0226 0.0408
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0016 0.0004 0.0004
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Inositol monophosphatase family protein 0.0021 0.0017 0.003
Leishmania major sterol C-24 reductase, putative 0.0047 0.0096 0.0173
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0016 0.0004 0.0029
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0196 0.0542 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0097 0.0246 0.0434
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0061 0.0138 0.1458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0212 0.0374
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.0522 0.0645
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0176 0.0311
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.002 0.017
Loa Loa (eye worm) cytochrome P450 0.0024 0.0026 0.0045
Toxoplasma gondii hypothetical protein 0.0325 0.0926 1
Loa Loa (eye worm) TYRA-2 protein 0.0097 0.0246 0.0434
Echinococcus granulosus glutamate receptor NMDA 0.0092 0.0231 0.0285
Mycobacterium ulcerans beta-lactamase 0.0112 0.0291 0.5336
Echinococcus granulosus atrial natriuretic peptide receptor 0.0018 0.0009 0.001
Schistosoma mansoni rab6-interacting 0.0022 0.002 0.0035
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0013 0.0023
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0023 0.0041
Echinococcus multilocularis fmrfamide receptor 0.0097 0.0246 0.0246
Onchocerca volvulus 0.0112 0.0291 0.0512
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.0512 0.0901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0013 0.0023
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.0236 0.0236
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0097 0.0246 0.0434
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0097 0.0246 0.0246
Onchocerca volvulus 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.1869 0.554 0.9761
Plasmodium falciparum transporter, putative 0.0325 0.0926 1
Schistosoma mansoni hypothetical protein 0.0024 0.0026 0.0046
Brugia malayi MH2 domain containing protein 0.0249 0.0699 0.1231
Brugia malayi PAS domain containing protein 0.0058 0.0128 0.0225
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0325 0.0926 0.1145
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0325 0.0926 0.0926
Echinococcus multilocularis neuropeptide Y receptor 0.0097 0.0246 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0291 0.0525
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0097 0.0246 0.0304
Schistosoma mansoni amine GPCR 0.0097 0.0246 0.0434
Echinococcus granulosus transcription factor eb 0.0105 0.0268 0.0331
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Schistosoma mansoni coup transcription factor 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0106 0.0187
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Entamoeba histolytica hypothetical protein 0.0036 0.0062 0.1082
Schistosoma mansoni sodium/chloride dependent transporter 0.0325 0.0926 0.1632
Trypanosoma brucei NADH dehydrogenase 0.0016 0.0004 0.0007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0448 0.1295 0.6161
Echinococcus multilocularis G protein coupled receptor 139 0.0254 0.0714 0.0714
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0124 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0004 0.0007
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0026 0.0104
Brugia malayi Dopamine receptor 0.0097 0.0246 0.0434
Schistosoma mansoni glutamate synthase 0.0016 0.0004 0.0007
Onchocerca volvulus 0.0022 0.002 0.0034
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.019 0.0522 0.0522
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0011 0.0021
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0009 0.0015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0165 0.0448 0.0553
Onchocerca volvulus 0.0721 0.2109 0.3716
Loa Loa (eye worm) Smad1 0.0017 0.0006 0.0011
Schistosoma mansoni histamine h1 receptor 0.0097 0.0246 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Brugia malayi nuclear receptor NHR-88 0.0032 0.005 0.0088
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0026 0.0047
Brugia malayi Calcitonin receptor-like protein seb-1 0.0521 0.1511 0.2662
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0222 0.0619 0.1091
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0521 0.1511 0.2662
Onchocerca volvulus 0.0018 0.0009 0.0015
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0026 0.0104
Leishmania major cytochrome p450-like protein 0.0024 0.0026 0.0047
Mycobacterium ulcerans hypothetical protein 0.0109 0.028 0.5131
Brugia malayi hypothetical protein 0.0119 0.031 0.0547
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0222 0.0619 0.1091
Echinococcus multilocularis neuropeptide Y receptor 0.0097 0.0246 0.0246
Plasmodium vivax amine transporter, putative 0.0325 0.0926 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Leishmania major C-8 sterol isomerase-like protein 0.1869 0.554 1
Loa Loa (eye worm) hypothetical protein 0.0291 0.0825 0.1454
Brugia malayi Inositol monophosphatase family protein 0.0021 0.0017 0.003
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0011 0.0081
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0026 0.0407
Loa Loa (eye worm) glutamate receptor 0.0018 0.0009 0.0015
Echinococcus multilocularis neuropeptide s receptor 0.0097 0.0246 0.0246
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0018 0.0009 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0187
Echinococcus granulosus bloom syndrome protein 0.0025 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.004 0.0074 0.0131
Brugia malayi hypothetical protein 0.0112 0.0289 0.0508
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0041 0.058
Schistosoma mansoni nAChR subunit 0.0112 0.0289 0.0509
Brugia malayi intermediate filament protein 0.0086 0.0212 0.0374
Brugia malayi GnHR receptor homolog 0.0097 0.0246 0.0434
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0005 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.002 0.002
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0009
Brugia malayi Pre-SET motif family protein 0.0031 0.0049 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304
Toxoplasma gondii hypothetical protein 0.0325 0.0926 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0041 0.0402
Leishmania major cytochrome p450-like protein 0.0024 0.0026 0.0047
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0127 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0272 0.387
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0041 0.0402
Onchocerca volvulus 0.0086 0.0212 0.0374
Trichomonas vaginalis set domain proteins, putative 0.024 0.0674 0.9573
Echinococcus multilocularis dnaJ subfamily B 0.0803 0.2356 0.2356
Schistosoma mansoni acetylcholine receptor-related 0.0112 0.0289 0.0509
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0097 0.0246 0.0246
Onchocerca volvulus 0.0325 0.0926 0.1632
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0026 0.0407
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0212 0.0374
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0016 0.0004 0.0029
Echinococcus multilocularis neuropeptides capa receptor 0.0097 0.0246 0.0246
Brugia malayi G protein-coupled receptor F59B2.13 0.0097 0.0246 0.0434
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0096 0.0173
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0021 0.0017 0.0179
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.005 0.0062
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.013 0.0228
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0118
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0005 0.0007
Leishmania major C-14 sterol reductase, putative 0.0091 0.0226 0.0408
Loa Loa (eye worm) GABA receptor subunit 0.0111 0.0286 0.0503
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.005 0.0088
Schistosoma mansoni myosin xvIII 0.0097 0.0246 0.0434
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0016 0.0004 0.0007
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0013 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0721 0.2109 0.3716
Brugia malayi nuclear hormone receptor 0.0032 0.005 0.0088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0512 0.0511
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0093 0.0164
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0112 0.0289 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0173 0.0172
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0041 0.0689
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0448 0.1295 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.005 0.0088
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0097 0.0246 0.0246
Brugia malayi Smad1 0.0017 0.0006 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.1584 0.4688 0.4688
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0325 0.0926 0.1632
Schistosoma mansoni acetylcholine receptor subunit beta 0.0112 0.0289 0.0509
Onchocerca volvulus 0.0097 0.0246 0.0434
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0026 0.0407
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0099 0.0122
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0022 0.0195
Echinococcus granulosus allatostatin A receptor 0.0097 0.0246 0.0304
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0325 0.0926 0.1632
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.0002 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0013 0.0022
Mycobacterium tuberculosis Conserved protein 0.0112 0.0291 0.137
Echinococcus granulosus g-protein coupled receptor 0.0097 0.0246 0.0304
Echinococcus granulosus receptor type guanylyl cyclase 0.0018 0.0009 0.001
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0011 0.0081
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0272 0.0272
Echinococcus granulosus Squalene phytoene synthase 0.0077 0.0185 0.0228
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.005 0.0088
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0136 0.983
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0127 0.0157
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0034 0.0325
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Echinococcus granulosus neuropeptides capa receptor 0.0097 0.0246 0.0304
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0289 0.0508
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0011
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0291 0.0825 0.1454
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Loa Loa (eye worm) glutamate receptor 1 0.0172 0.0469 0.0826
Brugia malayi Serotonin receptor 0.0097 0.0246 0.0434
Brugia malayi MH2 domain containing protein 0.0017 0.0006 0.0011
Mycobacterium tuberculosis Probable reductase 0.0403 0.116 0.5519
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0097 0.0246 0.0246
Entamoeba histolytica hypothetical protein 0.0036 0.0062 0.1082
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0097 0.0246 0.0434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0099 0.0174
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0325 0.0926 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.005 0.0088
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0016 0.0004 0.0029
Entamoeba histolytica hypothetical protein 0.0018 0.0009 0.0085
Loa Loa (eye worm) melatonin receptor type 1A 0.0097 0.0246 0.0434
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Echinococcus multilocularis lamin 0.0086 0.0212 0.0212
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0097 0.0246 0.0434
Brugia malayi Ets-domain containing protein 0.0073 0.0173 0.0304
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0127
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0097 0.0246 0.0434
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0291 0.4133
Brugia malayi isocitrate dehydrogenase 0.0019 0.0011 0.002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0097 0.0246 0.0304
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0062 0.0077
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0272 0.048
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.002 0.002
Brugia malayi Pre-SET motif family protein 0.0211 0.0587 0.1034
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0173 0.0304
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0291 0.0825 0.1454
Onchocerca volvulus 0.0053 0.0112 0.0198
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Brugia malayi Cytochrome P450 family protein 0.0024 0.0026 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Echinococcus multilocularis sodium and chloride dependent glycine 0.0325 0.0926 0.0926
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0136 0.2458
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0291 0.137
Schistosoma mansoni sodium/chloride dependent transporter 0.1914 0.5675 1
Echinococcus granulosus nAChR subunit 0.0111 0.0286 0.0353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Brugia malayi Cytochrome P450 family protein 0.0024 0.0026 0.0045
Schistosoma mansoni zinc finger protein 0.0022 0.0022 0.0039
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Onchocerca volvulus 0.0018 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Trichomonas vaginalis esterase, putative 0.0112 0.0291 0.4133
Loa Loa (eye worm) norepinephrine transporter 0.1914 0.5675 1
Loa Loa (eye worm) hypothetical protein 0.0955 0.281 0.4951
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0138 0.025
Brugia malayi G protein-coupled receptor 0.0097 0.0246 0.0434
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.005 0.0088
Schistosoma mansoni hypothetical protein 0.0022 0.002 0.0035
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0272 0.048
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0088
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0222 0.0619 0.1091
Echinococcus granulosus nmda type glutamate receptor 0.0156 0.0421 0.052
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.1914 0.5675 1
Echinococcus multilocularis transcription factor eb 0.0105 0.0268 0.0268
Echinococcus multilocularis muscleblind protein 0.0158 0.0428 0.0428
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0007
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.0004 0.0007
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.0004 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0446 0.6342
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0127 0.0224
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0909 0.2673 0.4709
Onchocerca volvulus 0.0721 0.2109 0.3716
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0013 0.0023
Echinococcus multilocularis fmrfamide receptor 0.0097 0.0246 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0026 0.0104
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0015 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.005 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0699 0.1231
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.005 0.0088
Trypanosoma cruzi phytoene synthase, putative 0.0077 0.0185 0.0334
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0272 0.4992
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0112 0.0289 0.0508
Schistosoma mansoni neurotransmitter gated ion channel 0.0111 0.0286 0.0504
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0026 0.0407
Echinococcus multilocularis inositol monophosphatase 0.0021 0.0017 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.002 0.002
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0021 0.0017 0.0239
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0127 0.0127
Schistosoma mansoni lamin 0.0086 0.0212 0.0374
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0041 0.2756
Schistosoma mansoni transient receptor potential channel 0.0067 0.0156 0.0275
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0222 0.0619 0.0765
Echinococcus granulosus lamin dm0 0.0086 0.0212 0.0262
Onchocerca volvulus 0.0222 0.0619 0.1091
Echinococcus multilocularis neuropeptide FF receptor 2 0.0097 0.0246 0.0246
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.005 0.0062
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0061 0.0138 0.0244
Echinococcus granulosus tm gpcr rhodopsin 0.0097 0.0246 0.0304
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0112 0.0289 0.0508
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0007
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0064 0.0145 0.018
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0196 0.0542 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0222 0.0619 0.0765
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0222 0.0619 0.1091
Entamoeba histolytica hypothetical protein 0.0036 0.0062 0.1082
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0097 0.0246 0.0434
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0013 0.0023
Schistosoma mansoni nAChR subunit 0.0222 0.0619 0.1091
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0016 0.0004 0.0053
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0016 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0512 0.0901
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.002 0.0024
Echinococcus granulosus neuropeptides capa receptor 0.0097 0.0246 0.0304
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0011 0.0021
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0176 0.048 0.3708
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0136 0.0246
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Brugia malayi follicle stimulating hormone receptor 0.0322 0.0917 0.1616
Schistosoma mansoni polycystin 1-related 0.0022 0.002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0048 0.0099 0.0174
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0222 0.0619 0.1091
Echinococcus granulosus tm gpcr rhodopsin 0.0097 0.0246 0.0304
Brugia malayi Doublecortin family protein 0.0022 0.002 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0026 0.0104
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0136 0.0246
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0011 0.0011
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0096 0.0173
Echinococcus multilocularis sodium and chloride dependent glycine 0.0325 0.0926 0.0926
Brugia malayi G-protein coupled receptor 0.0097 0.0246 0.0434
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0003 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.002 0.0024
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0272 0.0337
Loa Loa (eye worm) neuropeptide F receptor 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0222 0.0619 0.1091
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.0704 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0005 0.001
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0021 0.0017 0.003
Loa Loa (eye worm) hypothetical protein 0.1914 0.5675 1
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0291 0.5336
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0061 0.0138 0.1458
Echinococcus granulosus microtubule associated protein 2 0.1584 0.4688 0.5793
Brugia malayi hypothetical protein 0.063 0.1839 0.3241
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0061 0.0138 0.0244
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0031 0.0054
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0061 0.0138 0.025
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0026 0.0104
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0325 0.0926 0.1632
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0011 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0112 0.0289 0.0508
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0041 0.0402
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0064 0.0145 0.0145
Echinococcus multilocularis glutamate synthase 0.0016 0.0004 0.0004
Schistosoma mansoni survival motor neuron protein 0.0053 0.0112 0.0198
Onchocerca volvulus 0.0043 0.0085 0.0149
Echinococcus multilocularis vesicular acetylcholine transporter 0.0909 0.2673 0.2673
Echinococcus granulosus muscleblind protein 0.0158 0.0428 0.0529
Plasmodium vivax hypothetical protein, conserved 0.0325 0.0926 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0272 0.0492
Echinococcus granulosus zinc finger protein 0.0022 0.0022 0.0027
Schistosoma mansoni transient receptor potential channel 0.0067 0.0156 0.0275
Brugia malayi Melatonin receptor type 1A 0.0097 0.0246 0.0434
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0097 0.0246 0.0304
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0021 0.0017 0.0236
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Brugia malayi Glutamate receptor 1 precursor 0.0172 0.0469 0.0826
Echinococcus multilocularis orexin receptor type 2 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0077 0.0185 0.0864
Brugia malayi mbt repeat family protein 0.0051 0.0106 0.0187
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0072 0.0089
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.0004 0.0007
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0222 0.0619 0.1091
Schistosoma mansoni glutamate receptor NMDA 0.0282 0.0798 0.1405
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0138 0.025
Brugia malayi hypothetical protein 0.0017 0.0005 0.0009
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0222 0.0619 0.1091
Loa Loa (eye worm) serotonin transporter b 0.1914 0.5675 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0061 0.0138 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0325 0.0926 0.1145
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0272 0.387
Brugia malayi MH2 domain containing protein 0.0017 0.0006 0.0011
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.0004 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0108 0.019
Echinococcus multilocularis neuropeptides capa receptor 0.0097 0.0246 0.0246
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0078 0.1101
Mycobacterium ulcerans lipase LipD 0.0112 0.0291 0.5336
Loa Loa (eye worm) G-protein coupled receptor 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0013 0.0176
Echinococcus granulosus serotonin receptor 0.0097 0.0246 0.0304
Echinococcus granulosus biogenic amine 5HT receptor 0.0097 0.0246 0.0304
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0041 0.058
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0013 0.0023
Schistosoma mansoni biogenic amine (5HT) receptor 0.0097 0.0246 0.0434
Onchocerca volvulus 0.024 0.0674 0.1187
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0047 0.0096 0.0169
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.006 0.006
Echinococcus multilocularis allatostatin A receptor 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0291 0.0825 0.102
Schistosoma mansoni hypothetical protein 0.0097 0.0246 0.0434
Loa Loa (eye worm) hypothetical protein 0.0045 0.0089 0.0157
Onchocerca volvulus 0.063 0.1839 0.3241
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0909 0.2673 0.4709
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0434
Echinococcus granulosus g protein coupled receptor 0.0097 0.0246 0.0304
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0725 0.0896
Echinococcus multilocularis somatostatin receptor 0.0097 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0112 0.0291 0.0512
Echinococcus multilocularis neuropeptide receptor A26 0.0097 0.0246 0.0246
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0291 0.0825 0.0825
Loa Loa (eye worm) RecQ helicase 0.0025 0.0031 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0097 0.0246 0.0304

Activities

Activity type Activity value Assay description Source Reference
Ratio (binding) = 18 Ratio between poly-dAdT and poly-dGdC binding ChEMBL. 8510102
Tm (binding) = 1.6 degrees C Thermal denaturation in alternating poly(dG-dC)-poly(dG-dC) homopolymer (GC) ChEMBL. 8510102
Tm (binding) = 13.3 degrees C Thermal denaturation in sonicated calf thymus DNA (CT DNA) ChEMBL. 8510102
Tm (binding) = 28.9 degrees C Thermal denaturation in alternating poly(dA-dT)poly(dA-dT) homopolymer (AT) ChEMBL. 8510102
Tm (binding) = 30.7 degrees C Thermal denaturation in sonicated poly(dA)-poly(dT) homopolymer (AT) ChEMBL. 8510102

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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