Detailed information for compound 105824

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 937.177 | Formula: C50H60N6O8S2
  • H donors: 6 H acceptors: 6 LogP: 4.19 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 3
  • SMILES: CS(=O)(=O)O.CS(=O)(=O)O.COc1ccc2c(c1)c1c([nH]2)ccc2c1cc(NCCN1CCC(CC1)C1CCN(CC1)CCNc1ccc3c(c1)c1c(cc3)[nH]c3c1cc(OC)cc3)cc2
  • InChi: 1S/C48H52N6O2.2CH4O3S/c1-55-37-9-13-43-41(29-37)47-39-27-35(7-3-33(39)5-11-45(47)51-43)49-19-25-53-21-15-31(16-22-53)32-17-23-54(24-18-32)26-20-50-36-8-4-34-6-12-46-48(40(34)28-36)42-30-38(56-2)10-14-44(42)52-46;2*1-5(2,3)4/h3-14,27-32,49-52H,15-26H2,1-2H3;2*1H3,(H,2,3,4)
  • InChiKey: OFKBEIMWSHDATA-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0171 0.0962
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0257 0.0372
Plasmodium vivax proteasome subunit alpha type-3, putative 0.005 0.0248 0.1392
Trypanosoma brucei proteasome beta 7 subunit 0.005 0.0248 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Schistosoma mansoni tyrosine kinase 0.0051 0.0257 0.0531
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0139 0.0842 0.0822
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0065 0.007
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0103 0.018
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0028 0.0059
Echinococcus granulosus FTZ F1 alpha 0.0139 0.0842 0.1296
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis Proteasome, subunit alpha beta 0.005 0.0248 0.0359
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0353 0.073
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0208 0.0712
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0458 0.0947
Loa Loa (eye worm) hypothetical protein 0.0524 0.3409 0.3395
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Schistosoma mansoni ran 0.0022 0.0065 0.0135
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0405 0.0838
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0012
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.005 0.0248 0.1259
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0172 0.0973
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0028 0.0007
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0208 0.0431
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0049 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0458 0.069
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0458 0.069
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0172 0.0973
Leishmania major cytochrome p450-like protein 0.0044 0.0208 0.0185
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0236 0.0213
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.005 0.0248 0.1392
Echinococcus granulosus neuropeptide receptor 0.0081 0.0458 0.069
Echinococcus granulosus RUN 0.0021 0.0056 0.0056
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.011 0.0647 0.0625
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0165 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0165 0.093
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.005 0.0248 0.1392
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0524 0.3409 0.3395
Echinococcus multilocularis neuropeptide FF receptor 2 0.0081 0.0458 0.069
Schistosoma mansoni cpg binding protein 0.0031 0.0121 0.0249
Leishmania major cardiolipin synthetase, putative 0.0018 0.0033 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0353 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0107 0.0601
Brugia malayi beta-lactamase 0.0038 0.0172 0.0151
Schistosoma mansoni myosin xvIII 0.0081 0.0458 0.0947
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0139 0.0842 0.0822
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0063 0.0336 0.1948
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0236 0.034
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0236 0.0215
Echinococcus granulosus jun protein 0.009 0.0514 0.0779
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.005 0.0248 0.0514
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0172 0.0973
Brugia malayi SRC-1 0.0051 0.0257 0.0235
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0052 0.005
Brugia malayi nuclear receptor RXR 0.0073 0.0405 0.0384
Giardia lamblia 20S proteasome alpha subunit 1 0.005 0.0248 0.1187
Loa Loa (eye worm) hypothetical protein 0.0106 0.0622 0.0601
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0165 0.0142
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0081 0.0458 0.0437
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0171 0.0148
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0208 0.0296
Echinococcus multilocularis peroxidasin 0.0028 0.0103 0.013
Entamoeba histolytica protein kinase, putative 0.0035 0.0151 0.0632
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Brugia malayi hypothetical protein 0.0073 0.0405 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0208 0.1139
Schistosoma mansoni regulator of G protein signaling 0.002 0.0052 0.0109
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0236 0.1181
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0353 0.0524
Schistosoma mansoni nuclear receptor 0.0065 0.0353 0.073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0399 0.0378
Onchocerca volvulus Bile acid receptor homolog 0.0139 0.0842 0.2891
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0172 0.015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Echinococcus multilocularis serotonin receptor 0.0211 0.1326 0.2059
Schistosoma mansoni tyrosine kinase 0.0051 0.0257 0.0531
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0353 0.0524
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0172 0.0151
Brugia malayi 20S proteasome alpha5 subunit 0.005 0.0248 0.0227
Echinococcus multilocularis orexin receptor type 2 0.0081 0.0458 0.069
Loa Loa (eye worm) PXA domain-containing protein 0.0025 0.0084 0.0063
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0081 0.0458 0.069
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0139 0.0842 0.0822
Schistosoma mansoni amine GPCR 0.0081 0.0458 0.0947
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.005 0.0248 0.1259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0124 0.0695
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.005 0.0248 0.0226
Echinococcus multilocularis cpg binding protein 0.0032 0.0132 0.0176
Echinococcus multilocularis ecdysone induced protein 78C 0.0139 0.0842 0.1296
Loa Loa (eye worm) fli-1 protein 0.0235 0.1483 0.1464
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0236 0.034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0028 0.01 0.0307
Loa Loa (eye worm) TYRA-2 protein 0.0081 0.0458 0.0437
Brugia malayi Importin beta-1 subunit 0.003 0.0119 0.0097
Leishmania major importin beta-1 subunit, putative 0.0025 0.008 0.0057
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0052 0.0031
Loa Loa (eye worm) hypothetical protein 0.0072 0.0393 0.0372
Onchocerca volvulus 0.0044 0.0208 0.0566
Loa Loa (eye worm) hypothetical protein 0.0073 0.0405 0.0384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0458 0.069
Schistosoma mansoni ets-related 0.0235 0.1483 0.3067
Onchocerca volvulus 0.0254 0.1609 0.5703
Echinococcus granulosus NCK adaptor protein 0.0016 0.0022 0.0002
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.005 0.0248 0.1392
Onchocerca volvulus 0.0021 0.0056 0.0008
Schistosoma mansoni regulator of G protein signaling 0.002 0.0052 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0172 0.0912
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0028 0.01 0.0125
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Echinococcus multilocularis expressed protein 0.0399 0.2576 0.4031
Schistosoma mansoni tyrosine kinase 0.0104 0.061 0.1262
Schistosoma mansoni adapter molecule crk 0.0016 0.0022 0.0045
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0052 0.005
Echinococcus multilocularis 0.0099 0.0574 0.0873
Brugia malayi proteasome subunit beta type 3 0.005 0.0248 0.0227
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0353 0.0332
Echinococcus multilocularis thyroid hormone receptor alpha 0.0273 0.1739 0.2711
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.005 0.0248 0.1392
Mycobacterium ulcerans hypothetical protein 0.0038 0.0172 0.0479
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0197 0.123 0.7573
Brugia malayi PXA domain containing protein 0.0025 0.0084 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0172 0.0912
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.005 0.0248 0.0226
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0066 0.0239
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.1124 0.3924
Loa Loa (eye worm) DR-78 0.0065 0.0353 0.0332
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0236 0.0213
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0103 0.0082
Onchocerca volvulus 0.0081 0.0458 0.1482
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Onchocerca volvulus Dual oxidase homolog 0.0028 0.0103 0.018
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0208 0.0296
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.005 0.0248 0.1392
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.005 0.0248 0.1392
Onchocerca volvulus 0.0258 0.1639 0.5816
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0038 0.0172 0.0906
Echinococcus multilocularis proteasome subunit alpha type 2 0.005 0.0248 0.0359
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.005 0.0248 0.1392
Plasmodium falciparum proteasome subunit beta type-4 0.005 0.0248 0.1392
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0172 0.015
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0028 0.01 0.0307
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0081 0.0458 0.069
Schistosoma mansoni retinoic acid receptor RXR 0.0244 0.1545 0.3195
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0208 0.0712
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.0257 0.0372
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0052 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0353 0.0332
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0514 0.0779
Schistosoma mansoni RAR-like nuclear receptor 0.0139 0.0842 0.1742
Schistosoma mansoni gabp alpha 0.0077 0.0432 0.0894
Loa Loa (eye worm) TK/EGFR protein kinase 0.0321 0.2057 0.204
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0066 0.0367
Schistosoma mansoni ran 0.0022 0.0065 0.0135
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.0187
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0139 0.0842 0.0822
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0208 0.0295
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0066 0.0072
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0018 0.0033 0.003
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0066 0.0072
Echinococcus multilocularis Proteasome subunit alpha type 7 0.005 0.0248 0.0359
Brugia malayi Protein kinase domain containing protein 0.0104 0.061 0.059
Schistosoma mansoni hypothetical protein 0.0134 0.0813 0.1682
Schistosoma mansoni Lamin B receptor (ERG24) 0.0051 0.0253 0.0524
Leishmania major proteasome beta 7 subunit, putative 0.005 0.0248 0.0226
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0208 0.0296
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.011 0.0647 0.0988
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0139 0.0187
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.005 0.0248 0.1259
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0353 0.073
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0063 0.0336 0.0497
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0065 0.0233
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0254 0.1608 0.3326
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0172 0.015
Brugia malayi Protein K4 0.0018 0.0033 0.0011
Brugia malayi Tyrosine-protein kinase abl-1 0.002 0.0049 0.0027
Echinococcus granulosus insulin receptor 0.0104 0.061 0.093
Toxoplasma gondii proteasome subunit alpha1, putative 0.005 0.0248 0.1392
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0208 0.0712
Echinococcus multilocularis Proteasome subunit alpha type 7 0.005 0.0248 0.0359
Echinococcus multilocularis growth factor receptor bound protein 2 0.0016 0.0022 0.0002
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0172 0.0912
Schistosoma mansoni hypothetical protein 0.0033 0.0139 0.0288
Mycobacterium tuberculosis Conserved protein 0.0038 0.0172 0.0912
Schistosoma mansoni hypothetical protein 0.0033 0.0139 0.0288
Schistosoma mansoni farnesyl pyrophosphate synthase 0.011 0.0647 0.1338
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0208 0.1134
Plasmodium vivax SET domain protein, putative 0.0033 0.0133 0.0662
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0353 0.073
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0208 0.0712
Echinococcus multilocularis neuropeptide receptor A26 0.0573 0.3737 0.5862
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0197 0.123 0.121
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Echinococcus multilocularis NCK adaptor protein 0.0016 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0139 0.0842 0.1296
Loa Loa (eye worm) PAS-3 protein 0.005 0.0248 0.0227
Loa Loa (eye worm) phospholipase D 0.0021 0.0054 0.0032
Echinococcus granulosus importin subunit beta 1 0.003 0.0119 0.0155
Loa Loa (eye worm) proteasome subunit alpha type 6 0.005 0.0248 0.0227
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0353 0.0524
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0139 0.0842 0.1296
Trichomonas vaginalis importin beta-1, putative 0.0025 0.008 0.0448
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.011 0.0647 0.3676
Schistosoma mansoni amine GPCR 0.0081 0.0458 0.0947
Brugia malayi sulfakinin receptor protein 0.0081 0.0458 0.0437
Trypanosoma brucei cardiolipin synthetase, putative 0.0038 0.0172 0.0149
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.005 0.0248 0.0359
Loa Loa (eye worm) TK protein kinase 0.0043 0.0204 0.0183
Echinococcus granulosus Proteasome subunit alpha beta 0.005 0.0248 0.0359
Echinococcus granulosus snurportin 1 0.0325 0.2082 0.3252
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Brugia malayi follicle stimulating hormone receptor 0.0081 0.0458 0.0437
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0073 0.0405 0.0384
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Leishmania major proteasome alpha 3 subunit, putative 0.005 0.0248 0.0226
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0171 0.0148
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0458 0.0947
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trypanosoma brucei proteasome beta-1 subunit, putative 0.005 0.0248 0.0226
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0081 0.0458 0.0437
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0172 0.0973
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0248 0.0514
Schistosoma mansoni tyrosine kinase 0.002 0.0049 0.0101
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.3118
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0458 0.069
Brugia malayi hypothetical protein 0.0028 0.0103 0.0082
Schistosoma mansoni glutathione synthetase 0.0028 0.01 0.0207
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0458 0.0437
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0236 0.0213
Schistosoma mansoni peroxidasin 0.0028 0.0103 0.0214
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.005 0.0248 0.0226
Echinococcus granulosus proteasome subunit alpha type 6 0.005 0.0248 0.0359
Echinococcus granulosus phospholipase D 0.0097 0.0563 0.0856
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0208 0.1134
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0063 0.0336 0.0314
Echinococcus granulosus fmrfamide receptor 0.0081 0.0458 0.069
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.01 0.0077
Schistosoma mansoni neuropeptide receptor 0.0081 0.0458 0.0947
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0458 0.069
Echinococcus granulosus g protein coupled receptor 0.0081 0.0458 0.069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0208 0.1134
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0022 0.0045
Leishmania major proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Schistosoma mansoni biogenic amine (5HT) receptor 0.0211 0.1326 0.2743
Brugia malayi beta-NAC-like protein 0.0037 0.0165 0.0144
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0018 0.0033 0.003
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.005 0.0248 0.0227
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0208 0.1134
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.005 0.0248 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0081 0.0458 0.0947
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0185 0.1147 0.1777
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi nuclear hormone receptor 0.0139 0.0842 0.0822
Leishmania major solanesyl-diphosphate synthase, putative 0.0028 0.01 0.0077
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.005 0.0248 0.0226
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.1139
Echinococcus granulosus 20S proteasome subunit alpha 6 0.005 0.0248 0.0359
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0429 0.278 0.2763
Leishmania major cytochrome p450-like protein 0.0044 0.0208 0.0185
Brugia malayi Nuclear hormone receptor-like 1 0.0139 0.0842 0.0822
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.005 0.0248 0.0226
Brugia malayi steroid hormone receptor 0.0139 0.0842 0.0822
Brugia malayi proteasome subunit alpha type 6 0.005 0.0248 0.0227
Brugia malayi multidrug resistance protein 3 0.0023 0.0066 0.0044
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.003 0.0119 0.0097
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0172 0.0479
Loa Loa (eye worm) steroid hormone receptor 0.0139 0.0842 0.0822
Loa Loa (eye worm) proteasome subunit beta type 1 0.0197 0.123 0.1211
Echinococcus granulosus allatostatin A receptor 0.0081 0.0458 0.069
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0353 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Brugia malayi nuclear receptor NHR-67 0.0065 0.0353 0.0332
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0139 0.0842 0.1296
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0208 0.0431
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0056 0.0056
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Leishmania major farnesyl pyrophosphate synthase 0.011 0.0647 0.0625
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0052 0.0031
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0172 0.0912
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0028 0.0012
Schistosoma mansoni hypothetical protein 0.0044 0.0208 0.0429
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0066 0.0044
Toxoplasma gondii proteasome subunit 0.005 0.0248 0.1392
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0081 0.0458 0.069
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0353 0.0332
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0066 0.0044
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0165 0.093
Brugia malayi G-protein coupled receptor 0.0081 0.0458 0.0437
Loa Loa (eye worm) cytochrome P450 0.0044 0.0208 0.0186
Echinococcus granulosus G protein coupled receptor 139 0.0081 0.0458 0.069
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.0005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.1139
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0066 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0139 0.0842 0.0822
Echinococcus granulosus orexin receptor type 2 0.0081 0.0458 0.069
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.011 0.0647 0.3915
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni alpha-1 adrenergic receptor 0.0081 0.0458 0.0947
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.005 0.0248 0.0226
Schistosoma mansoni smdr2 0.0023 0.0066 0.0137
Schistosoma mansoni regulator of G protein signaling 0.002 0.0052 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0133 0.0275
Brugia malayi isocitrate dehydrogenase 0.0017 0.0028 0.0007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0052 0.0109
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0458 0.069
Leishmania major sterol C-24 reductase, putative 0.0051 0.0253 0.0231
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0104 0.061 0.093
Schistosoma mansoni hypothetical protein 0.0181 0.1124 0.2324
Loa Loa (eye worm) hypothetical protein 0.0339 0.2177 0.216
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0172 0.0239
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0458 0.069
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0021 0.0054 0.0031
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Plasmodium falciparum proteasome subunit beta type-3, putative 0.005 0.0248 0.1392
Loa Loa (eye worm) cytochrome P450 family protein 0.0084 0.048 0.0459
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.073 0.4152
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0458 0.069
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0066 0.0072
Trypanosoma cruzi cytochrome P450, putative 0.007 0.0386 0.0363
Entamoeba histolytica hypothetical protein 0.0038 0.0172 0.077
Onchocerca volvulus Chorion peroxidase homolog 0.0028 0.0103 0.018
Onchocerca volvulus Notchless protein homolog 0.005 0.0248 0.0712
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0028 0.01 0.0455
Mycobacterium ulcerans beta-lactamase 0.0038 0.0172 0.0479
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0172 0.0479
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus transcription factor btf3 0.0037 0.0165 0.0228
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0172 0.0973
Schistosoma mansoni microtubule-associated protein tau 0.0737 0.4835 1
Echinococcus multilocularis subfamily T1A non peptidase ue 0.005 0.0248 0.0359
Mycobacterium ulcerans proteasome PrcB 0.0254 0.1608 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0244 0.1545 0.2404
Echinococcus multilocularis proteasome subunit alpha type 6 0.005 0.0248 0.0359
Brugia malayi conserved hypotetical protein 0.0065 0.0353 0.0332
Plasmodium falciparum proteasome subunit beta type-6, putative 0.005 0.0248 0.1392
Brugia malayi Cytochrome P450 family protein 0.007 0.0386 0.0365
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0185 0.1147 0.1128
Schistosoma mansoni lipoxygenase 0.0088 0.0504 0.1042
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.005 0.0248 0.0514
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.073 0.4152
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0028 0.01 0.0125
Echinococcus granulosus g-protein coupled receptor 0.0081 0.0458 0.069
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0197 0.123 0.121
Schistosoma mansoni hypothetical protein 0.0325 0.2082 0.4307
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0023 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0139 0.0842 0.0822
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0458 0.0437
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0139 0.0842 0.1296
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Onchocerca volvulus 0.0081 0.0458 0.1482
Loa Loa (eye worm) hypothetical protein 0.0033 0.0133 0.0112
Onchocerca volvulus Peroxidase homolog 0.0028 0.0103 0.018
Brugia malayi hypothetical protein 0.0021 0.0056 0.0035
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0049 0.0026
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0066 0.0072
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0103 0.0082
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0119 0.0096
Echinococcus granulosus Proteasome subunit alpha type 7 0.005 0.0248 0.0359
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0035
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0208 0.0296
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0236 0.0213
Giardia lamblia Proteasome subunit beta type 9 precursor 0.005 0.0248 0.1187
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.008 0.0448
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0134 0.0813 0.125
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Onchocerca volvulus Peroxidase homolog 0.0028 0.0103 0.018
Brugia malayi Phospholipase D. Active site motif family protein 0.0021 0.0054 0.0032
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.005 0.0248 0.0226
Toxoplasma gondii ABC1 family protein 0.0038 0.0172 0.0912
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0179 0.0249
Schistosoma mansoni lipoxygenase 0.0126 0.0756 0.1565
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.005 0.0248 0.1259
Loa Loa (eye worm) hypothetical protein 0.0772 0.507 0.5059
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.005 0.0248 0.0226
Brugia malayi larval opioid receptor 0.0081 0.0458 0.0437
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0311 0.1792
Schistosoma mansoni multidrug resistance protein 0.0023 0.0066 0.0137
Leishmania major cytochrome p450-like protein 0.007 0.0386 0.0363
Onchocerca volvulus 0.0044 0.0208 0.0566
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0139 0.0842 0.1296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0494
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0049 0.0101
Brugia malayi Proteasome A-type and B-type family protein 0.0254 0.1608 0.159
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.1757 0.1739
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0208 0.0185
Entamoeba histolytica hypothetical protein 0.0025 0.008 0.0179
Loa Loa (eye worm) hypothetical protein 0.0073 0.0405 0.0384
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0121 0.0158
Echinococcus granulosus subfamily T1A non peptidase ue 0.005 0.0248 0.0359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0236 0.1336
Echinococcus multilocularis phospholipase D 0.0097 0.0563 0.0856
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0208 0.0712
Onchocerca volvulus 0.0028 0.0103 0.018
Echinococcus granulosus farnesyl pyrophosphate synthase 0.011 0.0647 0.0988
Echinococcus granulosus dnaJ subfamily B 0.0437 0.2831 0.4433
Schistosoma mansoni histamine h1 receptor 0.0081 0.0458 0.0947
Trichomonas vaginalis abcb9, putative 0.0023 0.0066 0.0367
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.005 0.0248 0.0226
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0458 0.0947
Schistosoma mansoni tyrosine kinase 0.0169 0.1046 0.2164
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.0204 0.029
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0056 0.0177
Echinococcus granulosus proteasome subunit beta t family 0.005 0.0248 0.0359
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0172 0.0357
Loa Loa (eye worm) PDE1B protein 0.0185 0.1147 0.1128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0122
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0197 0.123 0.761
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.005 0.0248 0.0514
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus epidermal growth factor receptor 0.0321 0.2057 0.3212
Trypanosoma cruzi Emopamil binding protein, putative 0.0429 0.278 0.2763
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0081 0.0458 0.069
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0134 0.0813 0.125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0103 0.0082
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0458 0.0947
Echinococcus granulosus g protein coupled receptor 0.0081 0.0458 0.069
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0208 0.0712
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.005 0.0248 0.1259
Brugia malayi cytochrome P450 0.0044 0.0208 0.0186
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0081 0.0458 0.1482
Echinococcus granulosus proteasome subunit beta type 6 0.005 0.0248 0.0359
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0018 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0073 0.0405 0.0384
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0236 0.1181
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0257 0.0372
Onchocerca volvulus 0.0081 0.0458 0.1482
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.005 0.0248 0.1259
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0122 0.073 0.4444
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0139 0.0842 0.1296
Brugia malayi nuclear hormone receptor 0.0065 0.0353 0.0332
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0208 0.0296
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0172 0.0912
Giardia lamblia Proteasome subunit beta type 3 0.005 0.0248 0.1187
Plasmodium vivax cardiolipin synthetase, putative 0.0018 0.0033 0.003
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0208 0.1134
Brugia malayi nuclear receptor NHR-88 0.0065 0.0353 0.0332
Schistosoma mansoni hypothetical protein 0.0081 0.0458 0.0947
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0066 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0208 0.1134
Onchocerca volvulus 0.0033 0.0133 0.029
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0092 0.0532 0.0511
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0081 0.0458 0.0947
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0081 0.0458 0.0947
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.011 0.0647 0.3915
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0197 0.123 0.121
Echinococcus multilocularis neuropeptide s receptor 0.0573 0.3737 0.5862
Loa Loa (eye worm) hypothetical protein 0.0033 0.0139 0.0118
Echinococcus multilocularis epidermal growth factor receptor 0.0321 0.2057 0.3212
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.005 0.0248 0.0226
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0028 0.0005
Brugia malayi Serotonin receptor 0.0573 0.3737 0.3723
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis serotonin receptor 0.0211 0.1326 0.2059
Echinococcus multilocularis transcription factor btf3 0.0037 0.0165 0.0228
Schistosoma mansoni hypothetical protein 0.0072 0.0399 0.0824
Schistosoma mansoni hypothetical protein 0.0081 0.0458 0.0947
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0081 0.0458 0.0947
Schistosoma mansoni transcription factor btf3 0.0037 0.0165 0.0341
Brugia malayi Cytochrome P450 family protein 0.0084 0.048 0.0459
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Echinococcus multilocularis insulin receptor 0.0104 0.061 0.093
Loa Loa (eye worm) polyprenyl synthetase 0.0028 0.01 0.0079
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Schistosoma mansoni neuropeptide receptor 0.0081 0.0458 0.0947
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0065 0.0042
Leishmania major proteasome beta 5 subunit, putative 0.0254 0.1608 0.1588
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.0257 0.0372
Echinococcus granulosus lamin b receptor 0.0051 0.0253 0.0367
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0065 0.007
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0052 0.005
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.005 0.0248 0.1259
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0056 0.0177
Schistosoma mansoni hypothetical protein 0.0081 0.0458 0.0947
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0756 0.1161
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0139 0.0842 0.1296
Brugia malayi ORL1-like opioid receptor 0.0081 0.0458 0.0437
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.005 0.0248 0.1392
Echinococcus granulosus growth factor receptor bound protein 2 0.0016 0.0022 0.0002
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0052 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Schistosoma mansoni axis inhibition protein axin 0.002 0.0052 0.0109
Trypanosoma cruzi Emopamil binding protein, putative 0.0429 0.278 0.2763
Loa Loa (eye worm) polyprenyl synthetase 0.011 0.0647 0.0626
Schistosoma mansoni hypothetical protein 0.0038 0.0172 0.0356
Schistosoma mansoni amine GPCR 0.0081 0.0458 0.0947
Brugia malayi proteasome subunit alpha type 3 0.005 0.0248 0.0227
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0052 0.005
Plasmodium vivax proteasome subunit alpha type-1, putative 0.005 0.0248 0.1392
Toxoplasma gondii peptidase, T1 family protein 0.005 0.0248 0.1392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0496
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.0005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0165 0.0142
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0034 0.0144 0.0122
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0081 0.0458 0.069
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0052 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.005 0.0248 0.1259
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0066 0.0072
Brugia malayi hypothetical protein 0.0018 0.0033 0.0011
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0028 0.01 0.0455
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0122 0.073 0.0709
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0107 0.0601
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.0125
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0056 0.0056
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Schistosoma mansoni rab6-interacting 0.0021 0.0056 0.0117
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0139 0.0842 0.1296
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0139 0.0842 0.0822
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0119 0.0096
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.005 0.0248 0.0226
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.005 0.0248 0.0514
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0052 0.005
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0432 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Onchocerca volvulus 0.0081 0.0458 0.1482
Trypanosoma brucei proteasome beta 3 subunit, putative 0.005 0.0248 0.0226
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0208 0.0185
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0092 0.0532 0.0511
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0353 0.0524
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0514 0.0779
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0052 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Onchocerca volvulus 0.0065 0.0353 0.1096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0139 0.0842 0.0822
Onchocerca volvulus 0.0081 0.0458 0.1482
Schistosoma mansoni neuropeptide receptor 0.0081 0.0458 0.0947
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0458 0.069
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0458 0.069
Trichomonas vaginalis esterase, putative 0.0038 0.0172 0.0973
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0081 0.0458 0.0437
Brugia malayi proteasome subunit beta type 1 0.0197 0.123 0.1211
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0139 0.0842 0.1742
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.2831 0.4433
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0056 0.0056
Schistosoma mansoni loxhd1 0.0021 0.0056 0.0117
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0171 0.0962
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.0187
Trichomonas vaginalis abcb9, putative 0.0023 0.0066 0.0367
Brugia malayi G protein-coupled receptor F59B2.13 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Leishmania major polyprenyl synthase, putative 0.0028 0.01 0.0077
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0028 0.01 0.0079
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.005 0.0248 0.0514
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0066 0.0072
Echinococcus multilocularis proteasome subunit beta type 7 0.005 0.0248 0.0359
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0056 0.0056
Brugia malayi ecdysone receptor 0.0065 0.0353 0.0332
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0208 0.1134
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.3118
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.01 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0107 0.0601
Echinococcus granulosus geminin 0.0181 0.1124 0.174
Echinococcus multilocularis somatostatin receptor 0.0081 0.0458 0.069
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0208 0.0296
Loa Loa (eye worm) proteasome subunit alpha type 2 0.005 0.0248 0.0227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0012
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0122 0.073 0.0709
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0179 0.0249
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0049 0.0044
Plasmodium falciparum transporter, putative 0.0044 0.0208 0.1139
Brugia malayi Serotonin receptor 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0353 0.0524
Toxoplasma gondii heat shock protein hslv, putative 0.005 0.0248 0.1392
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0386 0.0365
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0052 0.0109
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0065 0.0233
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0052 0.005
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0172 0.0356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0172 0.0357
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0172 0.0151
Onchocerca volvulus 0.0081 0.0458 0.1482
Echinococcus multilocularis 0.0044 0.0208 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0139 0.0842 0.0822
Onchocerca volvulus 0.0081 0.0458 0.1482
Schistosoma mansoni nuclear hormone receptor 0.0139 0.0842 0.1742
Onchocerca volvulus 0.0081 0.0458 0.1482
Echinococcus multilocularis lamin b receptor 0.0051 0.0253 0.0367
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Schistosoma mansoni rab6-interacting 0.0021 0.0056 0.0117
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni adenoreceptor 0.0081 0.0458 0.0947
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0052 0.0031
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0065 0.0042
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Onchocerca volvulus 0.0081 0.0458 0.1482
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.011 0.0647 0.3676
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0236 0.0488
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0139 0.0187
Echinococcus granulosus tm gpcr rhodopsin 0.0966 0.636 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0208 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0052 0.0031
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0066 0.0088
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.005 0.0248 0.0359
Entamoeba histolytica proteasome subunit beta type 3, putative 0.005 0.0248 0.1259
Onchocerca volvulus 0.0081 0.0458 0.1482
Trypanosoma brucei proteasome beta 2 subunit, putative 0.005 0.0248 0.0226
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.005 0.0248 0.1392
Schistosoma mansoni hypothetical protein 0.0033 0.0139 0.0288
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0173 0.1073 0.166
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0458 0.069
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0203 0.042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0139 0.0842 0.1296
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0066 0.0367
Mycobacterium tuberculosis Conserved protein 0.0038 0.0172 0.0912
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0122 0.073 0.1119
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0028 0.01 0.0125
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.0204 0.029
Schistosoma mansoni hypothetical protein 0.0181 0.1124 0.2324
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0208 0.0712
Onchocerca volvulus 0.0065 0.0353 0.1096
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0081 0.0458 0.0437
Echinococcus granulosus tyrosine kinase 0.0043 0.0204 0.029
Trypanosoma brucei ATP-dependent protease subunit HslV 0.005 0.0248 0.0226
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0432 0.0411
Mycobacterium leprae Probable lipase LipE 0.0038 0.0172 0.0479
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0197 0.123 0.761
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0353 0.0524
Echinococcus multilocularis phospholipase D1 0.011 0.0649 0.0991
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.005 0.0248 0.0226
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0172 0.0239
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0066 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0139 0.0842 0.1742
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0254 0.1608 1
Plasmodium vivax proteasome subunit alpha type-7, putative 0.005 0.0248 0.1392
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0254 0.1608 0.1588
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0458 0.0947
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0028 0.0007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0081 0.0458 0.0947
Schistosoma mansoni tyrosine kinase 0.0104 0.061 0.1262
Schistosoma mansoni hypothetical protein 0.0437 0.2831 0.5856
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0236 0.1336
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0254 0.1608 0.1588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0139 0.0842 0.0822
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0121 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0049 0.0044
Schistosoma mansoni hypothetical protein 0.0021 0.0056 0.0117
Brugia malayi Proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0151
Plasmodium vivax importin-beta 2, putative 0.003 0.0119 0.0572
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.005 0.0248 0.1392
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi hypothetical protein 0.0044 0.0208 0.0187
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0197 0.123 0.1908
Entamoeba histolytica phospholipase D, putative 0.011 0.0649 0.3835
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0405 0.0384
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0139 0.0842 0.0822
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.1404 0.1385
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0139 0.0842 0.1742
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.005 0.0248 0.0514
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0208 0.0712
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0067 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0172 0.0479
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0066 0.0043
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0151 0.0205
Echinococcus granulosus tachykinin peptides receptor 99D 0.0081 0.0458 0.069
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Brugia malayi AKH receptor 0.0081 0.0458 0.0437
Trichomonas vaginalis ran, putative 0.0022 0.0065 0.0361
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0208 0.0712
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0103 0.0082
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0081 0.0458 0.0947
Echinococcus multilocularis sex peptide receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Giardia lamblia 20S proteasome alpha subunit 4 0.005 0.0248 0.1187
Onchocerca volvulus 0.0081 0.0458 0.1482
Trichomonas vaginalis taga, putative 0.0023 0.0066 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0236 0.1336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0122
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0139 0.0842 0.1742
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0023 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0171 0.0962
Giardia lamblia Proteasome subunit beta type 2 0.0122 0.073 0.4312
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0208 0.1139
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Brugia malayi proteasome subunit alpha type 4 0.005 0.0248 0.0227
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0353 0.073
Echinococcus granulosus epidermal growth factor receptor 0.0173 0.1073 0.166
Echinococcus multilocularis serotonin transporter 0.0258 0.1639 0.2553
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0081 0.0458 0.0437
Brugia malayi Fli-1 protein 0.0235 0.1483 0.1464
Brugia malayi Proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Brugia malayi Polyprenyl synthetase family protein 0.011 0.0647 0.0626
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0458 0.0947
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0139 0.0842 0.2891
Loa Loa (eye worm) proteasome subunit beta type 2 0.0122 0.073 0.071
Onchocerca volvulus 0.0028 0.0103 0.018
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0171 0.0148
Giardia lamblia Proteasome subunit beta type 4 precursor 0.005 0.0248 0.1187
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0172 0.0149
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0139 0.0842 0.1742
Schistosoma mansoni amine GPCR 0.0081 0.0458 0.0947
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0066 0.0072
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0458 0.069
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0063 0.0336 0.1948
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0028 0.01 0.0455
Entamoeba histolytica hypothetical protein 0.0038 0.0172 0.077
Trypanosoma brucei proteasome beta 6 subunit 0.0197 0.123 0.121
Schistosoma mansoni neuropeptide receptor 0.0081 0.0458 0.0947
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis proteasome (prosome, macropain) 0.0254 0.1608 0.2504
Brugia malayi Furin-like cysteine rich region family protein 0.0321 0.2057 0.204
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.0257 0.0372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0248 0.1405
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0458 0.0437
Schistosoma mansoni polycystin 1-related 0.0021 0.0056 0.0117
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0208 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Loa Loa (eye worm) blistered cuticle protein 3 0.0028 0.0103 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0208 0.1134
Echinococcus multilocularis g-protein coupled receptor 0.0081 0.0458 0.069
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0139 0.0842 0.0822
Brugia malayi hypothetical protein 0.013 0.0783 0.0763
Brugia malayi tailless protein 0.0065 0.0353 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Brugia malayi Polyprenyl synthetase family protein 0.0028 0.01 0.0079
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0185 0.1147 0.2373
Giardia lamblia GTOR 0.0048 0.0236 0.1108
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0066 0.0072
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0066 0.0239
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0458 0.069
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0139 0.0118
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.005 0.0248 0.0226
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0028 0.01 0.0455
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.005 0.0248 0.1392
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.011 0.0647 0.3625
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0122
Echinococcus multilocularis geminin 0.0181 0.1124 0.174
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0458 0.069
Entamoeba histolytica phospholipase D, putative 0.011 0.0649 0.3835
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0023 0.0004
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0122 0.073 0.1119
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0052 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0353 0.0524
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0081 0.0458 0.0437
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0028 0.01 0.0125
Echinococcus multilocularis conserved hypothetical protein 0.0737 0.4835 0.7593
Loa Loa (eye worm) hypothetical protein 0.0258 0.1639 0.1621
Echinococcus granulosus peroxidasin 0.0028 0.0103 0.013
Mycobacterium tuberculosis Conserved protein 0.0038 0.0172 0.0912
Echinococcus granulosus 7tm_1 domain containing protein 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus neuropeptide FF receptor 2 0.0081 0.0458 0.069
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.005 0.0248 0.0514
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0081 0.0458 0.0437
Mycobacterium ulcerans lipase LipD 0.0038 0.0172 0.0479
Loa Loa (eye worm) TK protein kinase 0.0035 0.0151 0.0129
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0066 0.0367
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0172 0.0912
Echinococcus multilocularis importin subunit beta 1 0.003 0.0119 0.0155
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.005 0.0248 0.1259
Loa Loa (eye worm) hypothetical protein 0.0022 0.0065 0.0043
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0432 0.0649
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0208 1
Echinococcus granulosus somatostatin receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0353 0.0332
Brugia malayi Tachykinin-like peptides receptor 99D 0.0081 0.0458 0.0437
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.005 0.0248 0.0514
Schistosoma mansoni biogenic amine receptor 0.0081 0.0458 0.0947
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0756 0.1161
Brugia malayi Pre-SET motif family protein 0.0033 0.0133 0.0112
Brugia malayi putative neuropeptide receptor 0.0081 0.0458 0.0437
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0172 0.0149
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0016 0.0022 0.0045
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0052 0.005
Brugia malayi proteasome subunit beta type 2 0.0122 0.073 0.071
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0092 0.0532 0.3081
Echinococcus granulosus phospholipase d3 0.0021 0.0054 0.0053
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.0204 0.029
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0258 0.1639 0.3391
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0429 0.278 0.2763
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1511 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0139 0.0842 0.1296
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.1757 0.1739
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0052 0.0031
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0165 0.0142
Plasmodium vivax proteasome subunit beta type-4, putative 0.005 0.0248 0.1392
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0458 0.0947
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0208 0.0185
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0211 0.1326 0.1307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.005 0.0248 0.1259
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0081 0.0458 0.0437
Onchocerca volvulus 0.0038 0.0172 0.0434
Brugia malayi protein-tyrosine kinase 0.0043 0.0204 0.0183
Echinococcus multilocularis G protein coupled receptor 139 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0066 0.0357 0.0336
Entamoeba histolytica Ran family GTPase 0.0022 0.0065 0.0082
Echinococcus granulosus serotonin transporter 0.0258 0.1639 0.2553
Giardia lamblia 20S proteasome alpha subunit 7 0.005 0.0248 0.1187
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0139 0.0842 0.0822
Leishmania major proteasome alpha 2 subunit, putative 0.005 0.0248 0.0226
Brugia malayi hypothetical protein 0.0021 0.0056 0.0035
Brugia malayi RNA, U transporter 1 0.0086 0.0493 0.0472
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0081 0.0458 0.069
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.005 0.0248 0.1259
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.01 0.0077
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0103 0.018
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0154 0.0795
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0208 0.0712
Plasmodium vivax proteasome subunit beta type-3, putative 0.005 0.0248 0.1392
Brugia malayi hypothetical protein 0.0073 0.0405 0.0384
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.005 0.0248 0.0359
Plasmodium vivax proteasome subunit beta type-2, putative 0.0122 0.073 0.4444
Loa Loa (eye worm) hypothetical protein 0.0073 0.0405 0.0384
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.0125
Schistosoma mansoni jun-related protein 0.0073 0.0402 0.0832
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus hypothetical protein 0.0818 0.5377 0.8448
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0208 0.0712
Leishmania major proteasome beta 2 subunit, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0177 0.0247
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0065 0.0069
Toxoplasma gondii hypothetical protein 0.0044 0.0208 0.1139
Brugia malayi Ets-domain containing protein 0.0077 0.0432 0.0411
Echinococcus multilocularis epidermal growth factor receptor 0.0173 0.1073 0.166
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni thyroid hormone receptor 0.0273 0.1739 0.3598
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.005 0.0248 0.0514
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0622 0.0601
Echinococcus granulosus peptide allatostatin:somatostatin 0.0081 0.0458 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0494
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.0187
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.0257 0.0372
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0044
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0063 0.0336 0.0314
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0066 0.0367
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0066 0.0239
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0208 0.0187
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0208 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0081 0.0458 0.0947
Loa Loa (eye worm) solute carrier family 6 member 4 0.0258 0.1639 0.1621
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0208 0.0712
Brugia malayi Peroxidasin 0.0028 0.0103 0.0082
Schistosoma mansoni tyrosine kinase 0.0169 0.1046 0.2164
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Giardia lamblia 20S proteasome alpha subunit 3 0.005 0.0248 0.1187
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0208 0.0296
Leishmania major proteasome beta 3 subunit, putative 0.005 0.0248 0.0226
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0023 0.0048
Brugia malayi hypothetical protein 0.0038 0.0172 0.0151
Echinococcus granulosus phospholipase D1 0.011 0.0649 0.0991
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0458 0.069
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.005 0.0248 0.1392
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0139 0.0842 0.0822
Brugia malayi Phospholipase d protein 1 0.011 0.0649 0.0629
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0103 0.0082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0161 0.091
Plasmodium vivax proteasome subunit alpha type-5, putative 0.005 0.0248 0.1392
Schistosoma mansoni amine GPCR 0.0435 0.2819 0.5831
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0208 0.1134
Echinococcus multilocularis RUN 0.0021 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0258 0.1639 0.1621
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0081 0.0458 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0052 0.0109
Brugia malayi Cytochrome P450 family protein 0.007 0.0386 0.0365
Schistosoma mansoni tyrosine kinase 0.0173 0.1073 0.222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0171 0.0962
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.0257 0.0372
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0028 0.01 0.0455
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0208 0.0712
Schistosoma mansoni peroxidasin 0.0028 0.0103 0.0214
Onchocerca volvulus 0.0081 0.0458 0.1482
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.007 0.0386 0.1894
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Schistosoma mansoni tyrosine kinase 0.0173 0.1073 0.222
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi nuclear receptor NHR-88 0.0139 0.0842 0.0822
Brugia malayi proteasome subunit alpha type 1 0.005 0.0248 0.0227
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0139 0.0842 0.1296
Echinococcus granulosus 7TM GPCR rhodopsin 0.0081 0.0458 0.069
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.3828
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0023 0.0001
Trypanosoma brucei C-14 sterol reductase, putative 0.0051 0.0253 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0028 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0103 0.0082
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Schistosoma mansoni neuropeptide f receptor 76f 0.0081 0.0458 0.0947
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0052 0.0109
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0056 0.0056
Echinococcus multilocularis proteasome subunit beta type 6 0.005 0.0248 0.0359
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0405 0.0384
Leishmania major p-glycoprotein 0.0023 0.0066 0.0043
Echinococcus granulosus microtubule associated protein 2 0.0737 0.4835 0.7593
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0353 0.0524
Schistosoma mansoni biogenic amine receptor 0.0081 0.0458 0.0947
Giardia lamblia 20S proteasome alpha subunit 6 0.005 0.0248 0.1187
Schistosoma mansoni opsin-like receptor 0.0081 0.0458 0.0947
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0458 0.0947
Leishmania major proteasome beta 2 subunit, putative 0.0122 0.073 0.0709
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0208 0.0296
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0353 0.0332
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0066 0.0239
Loa Loa (eye worm) RGS-3 protein 0.002 0.0052 0.0031
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0065 0.0043
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Schistosoma mansoni hypothetical protein 0.0033 0.0139 0.0288
Trypanosoma brucei cytochrome P450, putative 0.007 0.0386 0.0363
Schistosoma mansoni cytochrome P450 0.0044 0.0208 0.0429
Onchocerca volvulus 0.0038 0.0172 0.0434
Brugia malayi hypothetical protein 0.002 0.0052 0.0031
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0133 0.0177
Schistosoma mansoni nck2/grb4 0.0016 0.0022 0.0045
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0063 0.0336 0.0497
Brugia malayi photoreceptor-specific nuclear receptor 0.0139 0.0842 0.0822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.005 0.0248 0.0514
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.005 0.0248 0.1259
Schistosoma mansoni regulator of G protein signaling 0.002 0.0052 0.0109
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0063 0.0336 0.1948
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.005 0.0248 0.0226
Brugia malayi Dopamine receptor protein 2 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0353 0.1096
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0028 0.01 0.0077
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0236 0.0213
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0165 0.0865
Onchocerca volvulus 0.0021 0.0056 0.0008
Brugia malayi Pre-SET motif family protein 0.0223 0.1404 0.1385
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.005 0.0248 0.1259
Echinococcus granulosus tyrosine protein kinase Lyn 0.0051 0.0257 0.0372
Trypanosoma brucei proteasome alpha 7 subunit 0.005 0.0248 0.0226
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Echinococcus granulosus g protein coupled receptor 0.0081 0.0458 0.069
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0208 0.1134
Loa Loa (eye worm) hypothetical protein 0.0087 0.0498 0.0477
Loa Loa (eye worm) hypothetical protein 0.0073 0.0405 0.0384
Brugia malayi Steroid receptor seven-up type 2 0.0139 0.0842 0.0822
Schistosoma mansoni nuclear receptor 0.0065 0.0353 0.073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0204 0.029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0429 0.278 0.2763
Plasmodium falciparum importin beta, putative 0.003 0.0119 0.0572
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0139 0.0187
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.005 0.0248 0.1259
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Leishmania major proteasome beta-1 subunit, putative 0.005 0.0248 0.0226
Echinococcus granulosus axis inhibition protein axin 0.002 0.0052 0.005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0622 0.0601
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Trypanosoma cruzi cytochrome P450, putative 0.007 0.0386 0.0363
Schistosoma mansoni coup transcription factor 0.0139 0.0842 0.1742
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0172 0.0912
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0081 0.0458 0.0437
Brugia malayi putative neuropeptide receptor NPR1 0.0081 0.0458 0.0437
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0353 0.0332
Schistosoma mansoni multidrug resistance protein 0.0023 0.0066 0.0137
Brugia malayi RE15519p 0.0081 0.0458 0.0437
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0052 0.0289
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0165 0.0865
Trypanosoma cruzi sterol C-24 reductase, putative 0.0051 0.0253 0.0231
Schistosoma mansoni tyrosine kinase 0.002 0.0049 0.0101
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.008 0.0448
Loa Loa (eye worm) proteasome subunit alpha type 1 0.005 0.0248 0.0227
Giardia lamblia Proteasome subunit beta type 7 precursor 0.005 0.0248 0.1187
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.005 0.0248 0.1392
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Schistosoma mansoni opsin-like receptor 0.0081 0.0458 0.0947
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0208 0.0431
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0133 0.0177
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.011 0.0647 0.3625
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0105 0.059
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.005 0.0248 0.1392
Loa Loa (eye worm) melatonin receptor type 1A 0.0081 0.0458 0.0437
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.011 0.0647 0.0625
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Brugia malayi Melatonin receptor type 1A 0.0081 0.0458 0.0437
Echinococcus multilocularis allatostatin A receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0122
Brugia malayi hypothetical protein 0.0065 0.0353 0.0332
Schistosoma mansoni trans-prenyltransferase 0.0028 0.01 0.0207
Toxoplasma gondii proteasome subunit beta type, putative 0.0254 0.1608 1
Echinococcus granulosus expressed protein 0.0399 0.2576 0.4031
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0185 0.1147 0.1777
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0165 0.093
Toxoplasma gondii proteasome subunit alpha type, putative 0.005 0.0248 0.1392
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0081 0.0458 0.069
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0208 0.0296
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.005 0.0248 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Trypanosoma cruzi 20S proteasome subunit 0.0122 0.073 0.0709
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0197 0.123 0.7002
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0208 0.1134
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0358 0.074
Loa Loa (eye worm) hypothetical protein 0.0021 0.0056 0.0035
Loa Loa (eye worm) hypothetical protein 0.0211 0.1326 0.1307
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Brugia malayi G-protein coupled receptor 0.0081 0.0458 0.0437
Trichomonas vaginalis set domain proteins, putative 0.0254 0.1609 0.9157
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0208 0.0712
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0103 0.0082
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.011 0.0647 0.3915
Echinococcus multilocularis phospholipase d3 0.0021 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi Dopamine receptor protein 1 0.0081 0.0458 0.0437
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0236 0.0213
Echinococcus granulosus neuropeptide receptor A26 0.0573 0.3737 0.5862
Trypanosoma cruzi sterol C-24 reductase, putative 0.0051 0.0253 0.0231
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0208 0.0712
Plasmodium vivax proteasome subunit beta type-5, putative 0.0254 0.1608 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Schistosoma mansoni steroid hormone receptor ad4bp 0.0139 0.0842 0.1742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0189 0.1069
Echinococcus multilocularis G-protein coupled receptor, putative 0.0081 0.0458 0.069
Echinococcus granulosus ecdysone induced protein 78C 0.0139 0.0842 0.1296
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Onchocerca volvulus Protein ultraspiracle homolog 0.0139 0.0842 0.2891
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.2082 0.2065
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Schistosoma mansoni opsin-like receptor 0.0081 0.0458 0.0947
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.0204 0.029
Echinococcus granulosus c src tyrosine kinase 0.002 0.0049 0.0044
Echinococcus multilocularis Proteasome subunit alpha type 7 0.005 0.0248 0.0359
Trypanosoma brucei farnesyl pyrophosphate synthase 0.011 0.0647 0.0625
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0208 0.1134
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0081 0.0458 0.0947
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0052 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.0187
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0197 0.123 0.2545
Trichomonas vaginalis abcb9, putative 0.0023 0.0066 0.0367
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0028 0.0012
Echinococcus multilocularis snurportin 1 0.0325 0.2082 0.3252
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0052 0.0031
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0133 0.0662
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0254 0.1608 0.1588
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0021 0.0108
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.005 0.0248 0.0514
Schistosoma mansoni phospholipase D 0.011 0.0649 0.1342
Onchocerca volvulus 0.0139 0.0842 0.2891
Loa Loa (eye worm) hypothetical protein 0.0258 0.1639 0.1621
Plasmodium vivax proteasome subunit beta type-7, putative 0.005 0.0248 0.1392
Plasmodium falciparum proteasome subunit beta type-7, putative 0.005 0.0248 0.1392
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1124 0.6393
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0179 0.0157
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0139 0.0118
Brugia malayi hypothetical protein 0.007 0.0386 0.0365
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.011 0.0647 0.3915
Loa Loa (eye worm) TK/INSR protein kinase 0.0104 0.061 0.059
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0052 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0139 0.0842 0.0822
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0133 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0458 0.069
Echinococcus multilocularis GPCR, family 2 0.0033 0.0139 0.0187
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0208 0.0296
Plasmodium vivax proteasome subunit alpha type-2, putative 0.005 0.0248 0.1392
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0028 0.01 0.0207
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0073 0.0405 0.0838
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0028 0.0012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0622 0.0601
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.005 0.0248 0.0359
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0103 0.0082
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0063 0.0336 0.0314
Leishmania major hypothetical protein, conserved 0.0429 0.278 0.2763
Echinococcus multilocularis tyrosine protein kinase Abl 0.002 0.0049 0.0044
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) beta-lactamase 0.0038 0.0172 0.0151
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0139 0.0187
Brugia malayi Phospholipase D. Active site motif family protein 0.0038 0.0172 0.015
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Trypanosoma brucei C-8 sterol isomerase, putative 0.1511 1 1
Brugia malayi Proteasome subunit alpha type 1 0.005 0.0248 0.0227
Loa Loa (eye worm) hypothetical protein 0.0027 0.0094 0.0072
Echinococcus granulosus serotonin receptor 0.0081 0.0458 0.069
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0081 0.0458 0.069
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.005 0.0248 0.0514
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0133 0.0177
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0081 0.0458 0.069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0458 0.0947
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Plasmodium vivax proteasome subunit beta type-1, putative 0.0197 0.123 0.761
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0458 0.069
Brugia malayi beta-lactamase family protein 0.0038 0.0172 0.0151
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0353 0.0332
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0172 0.0912
Onchocerca volvulus 0.0031 0.0121 0.0244
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0208 0.1134
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0052 0.005
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0122 0.073 0.4444
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0052 0.005
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0208 0.1134
Brugia malayi CXXC zinc finger family protein 0.0031 0.0121 0.0099
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0052 0.0109
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0065 0.0233
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1555 0.9668
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0254 0.1608 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0208 0.1134
Loa Loa (eye worm) hypothetical protein 0.0072 0.0393 0.0372
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0353 0.0524
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0353 0.1096
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0028 0.01 0.0077
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0236 0.0215
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0161 0.091
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0139 0.0118
Loa Loa (eye worm) norepinephrine transporter 0.0258 0.1639 0.1621
Schistosoma mansoni zinc finger protein 0.0065 0.0353 0.073
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0208 0.0712
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0353 0.073
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0073 0.0405 0.0606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0496
Onchocerca volvulus 0.0081 0.0458 0.1482
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0066 0.1879
Mycobacterium leprae putative cytochrome p450 0.0044 0.0208 0.0712
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0399 0.0378
Leishmania major hypothetical protein, conserved 0.0038 0.0172 0.015
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.005 0.0248 0.0226
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis jun protein 0.009 0.0514 0.0779
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.008 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0208 0.1134
Mycobacterium ulcerans proteasome PrcA 0.005 0.0248 0.0982
Onchocerca volvulus Neuropeptide F receptor homolog 0.0081 0.0458 0.1482
Onchocerca volvulus 0.0081 0.0458 0.1482
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.005 0.0248 0.0359
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0103 0.0082
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0052 0.005
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0052 0.005
Echinococcus granulosus neuropeptide receptor 0.0081 0.0458 0.069
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0052 0.005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0458 0.069
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0104 0.061 0.093
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0172 0.0239
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.005 0.0248 0.1392
Loa Loa (eye worm) SRC-1 0.0051 0.0257 0.0235
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0458 0.069
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0208 0.0431
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.005 0.0248 0.1259
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0066 0.0072
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0066 0.0367
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.011 0.0647 0.3676
Onchocerca volvulus 0.0081 0.0458 0.1482
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.005 0.0248 0.0982
Echinococcus granulosus GPCR family 2 0.0033 0.0139 0.0187
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0248 0.1405
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Leishmania major basic transcription factor 3a, putative 0.0037 0.0165 0.0142
Loa Loa (eye worm) hypothetical protein 0.0044 0.0208 0.0187
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1189 0.6763
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0208 0.1134
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0208 0.0712
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.005 0.0248 0.0226
Brugia malayi G protein-coupled receptor 0.0081 0.0458 0.0437
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Brugia malayi Cytochrome P450 family protein 0.0044 0.0208 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Giardia lamblia Farnesyl diphosphate synthase 0.011 0.0647 0.377
Leishmania major C-8 sterol isomerase-like protein 0.1511 1 1
Trypanosoma cruzi C-14 sterol reductase, putative 0.0051 0.0253 0.0231
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0028 0.01 0.0079
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis dro:myosuppressin receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0353 0.0332
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0066 0.0072
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0208 0.0712
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0458 0.069
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0065 0.0069
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0208 0.0712
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0179 0.0157
Plasmodium vivax proteasome subunit alpha type-6, putative 0.005 0.0248 0.1392
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0052 0.005
Entamoeba histolytica hypothetical protein 0.0038 0.0172 0.077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0634 0.4147 0.6509
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0122 0.073 0.1511
Onchocerca volvulus 0.0081 0.0458 0.1482
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0208 0.0431
Onchocerca volvulus 0.007 0.0386 0.1217
Schistosoma mansoni axis inhibition protein axin 0.002 0.0052 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.1757 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0066 0.0367
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0018 0.0033 0.001
Plasmodium vivax proteasome subunit beta type-6, putative 0.005 0.0248 0.1392
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0063 0.0336 0.0314
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0065 0.0042
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0386 0.0365
Onchocerca volvulus 0.0028 0.0103 0.018
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0458 0.0437
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0119 0.0572
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0133 0.0275
Loa Loa (eye worm) hypothetical protein 0.0139 0.0842 0.0822
Schistosoma mansoni multidrug resistance protein 0.0023 0.0066 0.0137
Leishmania major proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Schistosoma mansoni tyrosine kinase 0.0169 0.1046 0.2164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0105 0.059
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0066 0.0088
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0066 0.0367
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0165 0.0724
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0254 0.1608 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0458 0.069
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0052 0.0109
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0208 0.0712
Trypanosoma brucei cardiolipin synthetase 0.0038 0.0172 0.0149
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0056 0.0035
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.0257 0.0372
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0208 0.1134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0056 0.0056
Plasmodium vivax proteasome subunit alpha type-4, putative 0.005 0.0248 0.1392
Brugia malayi hypothetical protein 0.002 0.0052 0.0031
Echinococcus multilocularis FTZ F1 alpha 0.0139 0.0842 0.1296
Echinococcus granulosus neuropeptide s receptor 0.0573 0.3737 0.5862
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0494
Trypanosoma brucei Emopamil binding protein, putative 0.0429 0.278 0.2763
Plasmodium falciparum proteasome subunit beta type-5 0.0254 0.1608 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.005 0.0248 0.1405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0154 0.0868
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.005 0.0248 0.0226
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0151 0.0205
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0066 0.0367
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.005 0.0248 0.0359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0496
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.005 0.0248 0.0227
Echinococcus granulosus dro:myosuppressin receptor 0.0081 0.0458 0.069
Schistosoma mansoni sodium/chloride dependent transporter 0.0258 0.1639 0.3391
Echinococcus granulosus biogenic amine 5HT receptor 0.0211 0.1326 0.2059
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0208 0.0296
Brugia malayi bZIP transcription factor family protein 0.009 0.0514 0.0494
Loa Loa (eye worm) hypothetical protein 0.0492 0.3199 0.3184
Loa Loa (eye worm) serotonin transporter b 0.0258 0.1639 0.1621
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.0257 0.0372
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0066 0.0072
Brugia malayi nuclear receptor RXR 0.0065 0.0353 0.0332
Onchocerca volvulus 0.0023 0.0066 0.0044
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0081 0.0458 0.0947
Schistosoma mansoni hypothetical protein 0.0081 0.0458 0.0947
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0066 0.0367
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Brugia malayi PXA domain containing protein 0.0025 0.0084 0.0063
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0066 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0044
Onchocerca volvulus 0.0081 0.0458 0.1482
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0208 0.0431
Leishmania major proteasome alpha 1 subunit, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) CYP4Cod1 0.007 0.0386 0.0365
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0966 0.636 1
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0018 0.0033 0.003
Giardia lamblia 20S proteasome alpha subunit 5 0.005 0.0248 0.1187
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0133 0.0275
Echinococcus granulosus axis inhibition protein axin 0.002 0.0052 0.005
Entamoeba histolytica hypothetical protein 0.0038 0.0172 0.077
Loa Loa (eye worm) hypothetical protein 0.1511 1 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.005 0.0248 0.0226
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0081 0.0458 0.069
Onchocerca volvulus 0.0429 0.278 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.0257 0.0372
Echinococcus granulosus alpha 1A adrenergic receptor 0.0081 0.0458 0.069
Loa Loa (eye worm) proteasome subunit beta type 3 0.005 0.0248 0.0227
Giardia lamblia Proteasome subunit beta type 1 0.0197 0.123 0.7553
Schistosoma mansoni biogenic amine receptor 0.0081 0.0458 0.0947
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0258 0.1639 0.1621
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0353 0.0524
Schistosoma mansoni cpg binding protein 0.0032 0.0132 0.0273
Brugia malayi Ets-domain containing protein 0.0077 0.0432 0.0411
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0139 0.0842 0.0822
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0208 0.1134
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0172 0.0239
Schistosoma mansoni thyroid hormone receptor 0.0273 0.1739 0.3598
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0171 0.1055 0.1632
Onchocerca volvulus 0.0038 0.0172 0.0434
Loa Loa (eye worm) proteasome subunit alpha type 3 0.005 0.0248 0.0227
Treponema pallidum sodium- and chloride- dependent transporter 0.0258 0.1639 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0066 0.0367
Schistosoma mansoni regulator of G protein signaling 0.002 0.0052 0.0109
Brugia malayi neuropeptide F receptor 0.0081 0.0458 0.0437
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0248 0.1405
Echinococcus granulosus sex peptide receptor 0.0081 0.0458 0.069
Toxoplasma gondii hypothetical protein 0.0044 0.0208 0.1139
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0458 0.069
Giardia lamblia 20S proteasome alpha subunit 2 0.005 0.0248 0.1187
Schistosoma mansoni importin beta-1 0.003 0.0119 0.0246
Brugia malayi hypothetical protein 0.0065 0.0353 0.0332
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0248 0.1405
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0257 0.0372
Brugia malayi proteasome subunit alpha type 2 0.005 0.0248 0.0227
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0122 0.073 0.1511
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0458 0.069
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0066 0.0088
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0208 0.0712
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.005 0.0248 0.0226
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0011
Loa Loa (eye worm) hypothetical protein 0.0081 0.0458 0.0437
Echinococcus granulosus proteasome prosome macropain 0.0254 0.1608 0.2504
Schistosoma mansoni hypothetical protein 0.0073 0.0402 0.0832
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0022 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Echinococcus granulosus cpg binding protein 0.0032 0.0132 0.0176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0103 0.0082
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0203 0.042
Echinococcus granulosus tm gpcr rhodopsin 0.0634 0.4147 0.6509
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0165 0.0865
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0208 0.1134
Trypanosoma cruzi C-14 sterol reductase, putative 0.0051 0.0253 0.0231
Brugia malayi ABC transporter family protein 0.0023 0.0066 0.0044
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0177 0.0247
Echinococcus granulosus proteasome subunit alpha type 2 0.005 0.0248 0.0359
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0066 0.0072
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0208 0.1139
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0066 0.0239
Brugia malayi beta-lactamase family protein 0.0038 0.0172 0.0151
Brugia malayi hypothetical protein 0.0081 0.0458 0.0437
Leishmania major GTP-binding protein, putative 0.0022 0.0065 0.0042
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0139 0.0842 0.1296
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0073 0.0405 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0139 0.0842 0.0822
Plasmodium vivax amine transporter, putative 0.0044 0.0208 0.1139
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0028 0.01 0.0307
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0122 0.073 0.4358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0171 0.0962
Leishmania major C-14 sterol reductase, putative 0.0051 0.0253 0.0231
Onchocerca volvulus 0.0044 0.0208 0.0566
Echinococcus granulosus proteasome subunit beta type 7 0.005 0.0248 0.0359
Leishmania major proteasome alpha 1 subunit, putative 0.005 0.0248 0.0226
Toxoplasma gondii proteasome beta subunit 0.005 0.0248 0.1392
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0197 0.123 0.1908
Brugia malayi Dopamine receptor 0.0081 0.0458 0.0437
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0066 0.0367
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0065 0.0043
Schistosoma mansoni cpg binding protein 0.0032 0.0132 0.0273
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0066 0.0088
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0353 0.0332
Brugia malayi Proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.005 0.0248 0.0227
Echinococcus multilocularis microtubule associated protein 2 0.0737 0.4835 0.7593
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0131 0.0735
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0254 0.1608 1
Brugia malayi Blistered cuticle protein 3 0.0028 0.0103 0.0082
Brugia malayi neuropeptide F receptor 0.0081 0.0458 0.0437
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0028 0.0005
Brugia malayi GnHR receptor homolog 0.0081 0.0458 0.0437
Brugia malayi Doublecortin family protein 0.0021 0.0056 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1189 0.6763
Entamoeba histolytica hypothetical protein 0.0037 0.0165 0.0724
Brugia malayi Proteasome subunit alpha type 7-1 0.005 0.0248 0.0227
Schistosoma mansoni tyrosine kinase 0.0321 0.2057 0.4255
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0254 0.1608 0.9153
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0139 0.0842 0.1742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0089 0.0496
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.01 0.0077
Brugia malayi ecdysteroid receptor 0.0139 0.0842 0.0822
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0254 0.1608 0.159
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.005 0.0248 0.0514
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0028 0.01 0.0455

Activities

Activity type Activity value Assay description Source Reference
CE37 (functional) = 0.024 uM In vitro inhibition of L1210 (mouse leukaemia) cell cloning efficiency. ChEMBL. 3669015
CE37 (functional) = 0.024 uM In vitro inhibition of L1210 (mouse leukaemia) cell cloning efficiency. ChEMBL. 3669015
ED50 (functional) = 0.19 uM In vitro cellular toxicity against L1210 (mouse leukamia) cells. ChEMBL. 3669015
ED50 (functional) = 0.19 uM In vitro cellular toxicity against L1210 (mouse leukamia) cells. ChEMBL. 3669015
K (binding) = 10000000 M-1 Binding affinity against calf-thymus DNA at pH 7.4 ChEMBL. 3669015
MTD (functional) = 10 mg kg-1 In vivo maximum tolerate dose in L1210 (mouse leukaemia) inoculated mice. ChEMBL. 3669015
MTD (functional) = 10 mg kg-1 In vivo maximum tolerate dose in L1210 (mouse leukaemia) inoculated mice. ChEMBL. 3669015
OD (functional) = 10 mg kg-1 In vivo antitumour activity in L1210 (mouse leukaemia) inoculated mice (optimal dose). ChEMBL. 3669015
OD (functional) = 10 mg kg-1 In vivo antitumour activity in L1210 (mouse leukaemia) inoculated mice (optimal dose). ChEMBL. 3669015
T/C (functional) = 182 % In vivo change in mean survival time in L1210 (mouse leukaemia) inoculated mice. ChEMBL. 3669015
T/C (functional) = 182 % In vivo change in mean survival time in L1210 (mouse leukaemia) inoculated mice. ChEMBL. 3669015

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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