Detailed information for compound 1073631

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 352.496 | Formula: C20H24N4S
  • H donors: 1 H acceptors: 0 LogP: 3.82 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCC[C@H]1CCn1ccc2c1ccc(c2)NC(=N)c1cccs1
  • InChi: 1S/C20H24N4S/c1-23-10-2-4-17(23)9-12-24-11-8-15-14-16(6-7-18(15)24)22-20(21)19-5-3-13-25-19/h3,5-8,11,13-14,17H,2,4,9-10,12H2,1H3,(H2,21,22)/t17-/m0/s1
  • InChiKey: PRVOGTVRVMVUHG-KRWDZBQOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0055 0.0204 0.1174
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0056 0.028
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0055
Plasmodium falciparum importin beta, putative 0.0075 0.0314 0.1582
Echinococcus multilocularis neuropeptides capa receptor 0.011 0.0505 0.0502
Mycobacterium ulcerans hypothetical protein 0.0176 0.087 0.0898
Loa Loa (eye worm) hypothetical protein 0.0661 0.3554 0.6217
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0055 0.0204 0.1015
Brugia malayi ImpB/MucB/SamB family protein 0.0029 0.0056 0.0095
Echinococcus granulosus sodium:glucose cotransporter 0.0026 0.0041 0.0038
Echinococcus granulosus histone deacetylase 6 0.0282 0.1458 0.1455
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0771 0.4399
Echinococcus granulosus tm gpcr rhodopsin 0.011 0.0505 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0037 0.0099 0.0171
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0226 0.1146 0.1143
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0305 0.0288
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0305 0.0305
Echinococcus granulosus high affinity choline transporter 1 0.0236 0.1202 0.1199
Brugia malayi Cytochrome P450 family protein 0.007 0.0286 0.0499
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0016 0.0057
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0123 0.0579 0.0601
Echinococcus multilocularis acetylcholinesterase 0.013 0.0614 0.0611
Loa Loa (eye worm) histone deacetylase 1 0.0323 0.1687 0.295
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0179 0.0885 0.0882
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0254 0.1301 0.1299
Echinococcus granulosus somatostatin receptor 0.011 0.0505 0.0502
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0305 0.0304
Brugia malayi Inositol-1 0.0042 0.0129 0.0223
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0159 0.0775 0.0773
Echinococcus granulosus ecdysone induced protein 78C 0.0037 0.0099 0.0096
Brugia malayi Cation transporter family protein 0.0226 0.1146 0.2002
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0438 0.257
Schistosoma mansoni inositol transporter 0.0026 0.0041 0.0041
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0056 0.0042
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni heat shock protein 0.0098 0.0438 0.0438
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trypanosoma brucei histone deacetylase 4 0.0282 0.1458 0.8354
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0032 0.0032
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0238 0.0235
Echinococcus granulosus RUN 0.0091 0.0401 0.0398
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Schistosoma mansoni hypothetical protein 0.002 0.0007 0.0007
Brugia malayi 6-phosphofructokinase 0.0073 0.0302 0.0527
Echinococcus multilocularis allatostatin A receptor 0.011 0.0505 0.0502
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Echinococcus granulosus glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Echinococcus granulosus alpha 1A adrenergic receptor 0.011 0.0505 0.0502
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0042 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Loa Loa (eye worm) steroid hormone receptor 0.0037 0.0099 0.0173
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0121 0.0094
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0107 0.0488 0.0481
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0111
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Onchocerca volvulus 0.0226 0.1146 0.1994
Echinococcus granulosus sodium and chloride dependent glycine 0.0179 0.0885 0.0882
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0064 0.0249 0.1444
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0037 0.0099 0.0096
Echinococcus multilocularis neuropeptides capa receptor 0.011 0.0505 0.0502
Brugia malayi Histone deacetylase 1 0.0323 0.1687 0.2949
Schistosoma mansoni neuropeptide receptor 0.011 0.0505 0.0505
Brugia malayi follicle stimulating hormone receptor 0.0359 0.1885 0.3296
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0124 0.0671
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Echinococcus multilocularis glycine receptor subunit beta 0.0226 0.1146 0.1143
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Leishmania major DNA polymerase eta, putative 0.0029 0.0056 0.028
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) hypothetical protein 0.0064 0.0249 0.0436
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0021 0.0011 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.011 0.0505 0.0502
Echinococcus multilocularis expressed protein 0.0306 0.1588 0.1585
Brugia malayi Tachykinin-like peptides receptor 99D 0.011 0.0505 0.0882
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0104 0.0093
Schistosoma mansoni survival motor neuron protein 0.0035 0.0093 0.0093
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0226 0.1146 0.1146
Onchocerca volvulus Neuropeptide F receptor homolog 0.011 0.0505 0.0873
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0098 0.0441 0.0772
Entamoeba histolytica hypothetical protein 0.0021 0.0014 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0194 0.0973 0.097
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Schistosoma mansoni biogenic amine receptor 0.011 0.0505 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0037 0.0099 0.0171
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0055 0.0204 0.0201
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.011 0.0505 0.0882
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0004 0.0004
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.011 0.0505 0.0884
Echinococcus granulosus acetylcholinesterase 0.013 0.0614 0.0611
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0109 0.0502 0.0876
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0055 0.0204 0.1132
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.011 0.0505 0.0502
Giardia lamblia Histone deacetylase 0.0323 0.1687 1
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0075 0.0314 0.0314
Onchocerca volvulus 0.011 0.0505 0.0873
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0109 0.0502 0.0876
Trypanosoma cruzi cytochrome P450, putative 0.007 0.0286 0.1608
Brugia malayi glutathione reductase 0.0075 0.0314 0.0548
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0444 0.2352 0.2349
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Treponema pallidum NADH oxidase 0.0026 0.0042 0.0037
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0024 0.0032 0.0054
Giardia lamblia Nuclear ATP/GTP-binding protein 0.002 0.0007 0.0003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0075 0.0314 0.0311
Leishmania major trypanothione reductase 0.0075 0.0314 0.1769
Schistosoma mansoni biogenic amine receptor 0.011 0.0505 0.0505
Brugia malayi G-protein coupled receptor 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0029 0.0056 0.0097
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0004 0.0001
Onchocerca volvulus 0.0226 0.1146 0.1994
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0037 0.0099 0.0171
Onchocerca volvulus 0.0109 0.0502 0.0866
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0121 0.011
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0056 0.0283
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.0774 0.418 0.4378
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0085 0.0366 0.214
Loa Loa (eye worm) zinc carboxypeptidase 0.002 0.0007 0.0012
Echinococcus multilocularis 6 phosphofructokinase 0.0073 0.0302 0.03
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0238 0.1213 0.1213
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0022 0.0018 0.0069
Trypanosoma cruzi polo-like protein kinase, putative 0.0034 0.0084 0.0444
Plasmodium falciparum heat shock protein 90, putative 0.0371 0.1949 1
Brugia malayi Bromodomain containing protein 0.0038 0.0107 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Schistosoma mansoni hypothetical protein 0.011 0.0505 0.0505
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0207 0.1041 0.1087
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0042 0.0027
Onchocerca volvulus 0.0116 0.0538 0.093
Loa Loa (eye worm) carboxylesterase 0.0022 0.0018 0.0032
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0129 0.0701
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.0032 0.0029
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0207 0.1041 0.6158
Echinococcus multilocularis histone deacetylase 1 0.0323 0.1687 0.1684
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0139 0.041
Plasmodium falciparum phd finger protein, putative 0.0025 0.0036 0.0154
Plasmodium vivax importin-beta 2, putative 0.0075 0.0314 0.095
Trichomonas vaginalis heat shock protein, putative 0.0092 0.0405 0.2372
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.011 0.0505 0.0502
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0254 0.1301 0.1301
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0016 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Echinococcus multilocularis solute carrier family 5 0.0026 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Toxoplasma gondii heat shock protein 90, putative 0.0098 0.0438 0.2223
Toxoplasma gondii TIM10 family protein, putative 0.0035 0.0093 0.0447
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Schistosoma mansoni alpha-1 adrenergic receptor 0.011 0.0505 0.0505
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0036 0.0033
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0004 0.0001
Echinococcus granulosus g protein coupled receptor 0.011 0.0505 0.0502
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0099 0.0099
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0121 0.011
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0121 0.011
Echinococcus granulosus carboxylesterase 5A 0.013 0.0614 0.0611
Trypanosoma cruzi heat shock protein 90, putative 0.0084 0.036 0.2033
Loa Loa (eye worm) neuropeptide F receptor 0.011 0.0505 0.0884
Giardia lamblia Heat shock protein HSP 90-alpha 0.0098 0.0438 0.257
Echinococcus multilocularis ubiquitin specific protease 41 0.0025 0.0036 0.0033
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Schistosoma mansoni endoplasmin 0.0098 0.0438 0.0438
Trichomonas vaginalis DNA polymerase eta, putative 0.0029 0.0056 0.0292
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0037 0.0099 0.0099
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0129 0.063
Loa Loa (eye worm) latrophilin receptor protein 2 0.0159 0.0775 0.1356
Loa Loa (eye worm) hypothetical protein 0.1052 0.5717 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0771 0.4401
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0029 0.0056 0.0053
Brugia malayi Carboxylesterase family protein 0.0022 0.0018 0.003
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0207 0.1041 0.5953
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0121 0.0656
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0179 0.0885 0.0882
Mycobacterium ulcerans DNA polymerase IV 0.0029 0.0056 0.0042
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0037 0.0099 0.0096
Echinococcus granulosus sodium:myo inositol cotransporter 0.0026 0.0041 0.0038
Mycobacterium leprae PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE) 0.174 0.9526 1
Brugia malayi steroid hormone receptor 0.0037 0.0099 0.0171
Loa Loa (eye worm) norepinephrine transporter 0.1052 0.5717 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1052 0.5717 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0022 0.0018 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.0073 0.0302 0.0302
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0035 0.0093 0.0447
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0228 0.116 0.1157
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0226 0.1146 0.1146
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0092 0.0507
Echinococcus granulosus biogenic amine 5HT receptor 0.011 0.0505 0.0502
Schistosoma mansoni hypothetical protein 0.011 0.0505 0.0505
Loa Loa (eye worm) LGC-31 protein 0.0226 0.1146 0.2004
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0121 0.011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0238
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0185 0.0324
Trypanosoma brucei histone deacetylase, putative 0.0282 0.1458 0.8354
Loa Loa (eye worm) hypothetical protein 0.004 0.012 0.0209
Brugia malayi hypothetical protein 0.0174 0.0858 0.15
Schistosoma mansoni neuropeptide receptor 0.011 0.0505 0.0505
Toxoplasma gondii Hsp90 domain-containing protein 0.0371 0.1949 1
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0065 0.0257 0.1489
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0055 0.0204 0.1132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0121 0.011
Loa Loa (eye worm) G-protein coupled receptor 0.011 0.0505 0.0884
Entamoeba histolytica hypothetical protein 0.0049 0.0171 0.0977
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0032 0.0129
Trypanosoma brucei Heat shock protein 83, putative 0.0098 0.0438 0.2486
Brugia malayi jmjC domain containing protein 0.0083 0.0354 0.0617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0036 0.0174
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0207 0.1041 0.6158
Brugia malayi Hsp90 protein 0.0065 0.0257 0.0447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0092 0.0507
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0019 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0159 0.0775 0.0773
Plasmodium vivax hypothetical protein, conserved 0.002 0.0007 0.0002
Mycobacterium tuberculosis Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase) 0.174 0.9526 1
Brugia malayi phosphofructokinase 0.0073 0.0302 0.0527
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0692 0.1209
Onchocerca volvulus Serine\/threonine kinase homolog 0.0034 0.0084 0.0135
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0027 0.0044 0.0041
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0035 0.0093 0.0268
Schistosoma mansoni biogenic amine (5HT) receptor 0.011 0.0505 0.0505
Brugia malayi cytoplasmic intermediate filament protein 0.0023 0.0024 0.004
Leishmania major cytochrome p450-like protein 0.004 0.0121 0.0656
Echinococcus multilocularis heat shock protein 0.0098 0.0438 0.0435
Trichomonas vaginalis spcc417.12 protein, putative 0.0022 0.0018 0.0069
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0305 0.1777
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0016 0.0049
Echinococcus granulosus sodium:glucose cotransporter 2 0.0026 0.0041 0.0038
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.011 0.0505 0.0505
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0305 0.0304
Toxoplasma gondii ABC1 family protein 0.0074 0.0305 0.1537
Echinococcus granulosus 7tm_1 domain containing protein 0.011 0.0505 0.0502
Onchocerca volvulus Huntingtin homolog 0.0098 0.0441 0.076
Schistosoma mansoni high-affinity choline transporter 0.0236 0.1202 0.1202
Schistosoma mansoni hypothetical protein 0.0657 0.3532 0.3532
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0042 0.0199
Loa Loa (eye worm) phosphofructokinase 0.0073 0.0302 0.0529
Brugia malayi MH1 domain containing protein 0.0034 0.0085 0.0147
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0042 0.0181
Brugia malayi Dopamine receptor 0.011 0.0505 0.0882
Echinococcus granulosus dna polymerase eta 0.0029 0.0056 0.0053
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus tm gpcr rhodopsin 0.011 0.0505 0.0502
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0034 0.0084 0.0147
Loa Loa (eye worm) hypothetical protein 0.0121 0.0567 0.0991
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0226 0.1146 0.1143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0226 0.1146 0.2002
Brugia malayi Carboxylesterase family protein 0.013 0.0614 0.1072
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Onchocerca volvulus 0.011 0.0505 0.0873
Echinococcus granulosus g-protein coupled receptor 0.011 0.0505 0.0502
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0129 0.0728
Schistosoma mansoni hypothetical protein 0.004 0.0121 0.0121
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0064 0.0294
Brugia malayi Carboxylesterase family protein 0.0022 0.0018 0.003
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Mycobacterium leprae HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE ACPS (HOLO-ACP SYNTHASE) (CoA:APO-[ACP]PANTETHEINEPHOSPHOTRANSFERASE) (CoA:APO-[ACYL-CARRIE 0.0099 0.0444 0.0435
Brugia malayi G protein-coupled receptor 0.011 0.0505 0.0882
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0099 0.0171
Loa Loa (eye worm) nuclear factor I 0.0019 0.0001 0.0002
Mycobacterium ulcerans UDP-N-acetylenolpyruvoylglucosamine reductase 0.174 0.9526 1
Loa Loa (eye worm) histone deacetylase 7A 0.0282 0.1458 0.255
Brugia malayi putative neuropeptide receptor NPR1 0.011 0.0505 0.0882
Brugia malayi CXXC zinc finger family protein 0.0073 0.0304 0.0529
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0077 0.0325 0.0569
Brugia malayi Smad1 0.0034 0.0085 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0121 0.011
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.011 0.0505 0.0884
Loa Loa (eye worm) endoplasmin 0.0098 0.0438 0.0767
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Schistosoma mansoni amine GPCR 0.011 0.0505 0.0505
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0085 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Brugia malayi photoreceptor-specific nuclear receptor 0.0037 0.0099 0.0171
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0218 0.1101 0.1098
Schistosoma mansoni sodium-dependent amino acid transporter 0.0179 0.0885 0.0885
Onchocerca volvulus Putative nachr subunit 0.0226 0.1146 0.1994
Trichomonas vaginalis phosphofructokinase, putative 0.0073 0.0302 0.1762
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0042 0.0108
Brugia malayi RNA binding protein 0.0193 0.0967 0.1689
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0683 0.0683
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0305 0.1716
Mycobacterium tuberculosis Probable dehydrogenase 0.0172 0.0849 0.0876
Brugia malayi ecdysteroid receptor 0.0037 0.0099 0.0171
Schistosoma mansoni peptidase 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Brugia malayi Serotonin receptor 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0305 0.0302
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0064 0.0249 0.1444
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0034
Onchocerca volvulus 0.0022 0.0018 0.002
Toxoplasma gondii histone deacetylase HDAC4 0.0258 0.1324 0.6784
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0099 0.0099
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Trichomonas vaginalis set domain proteins, putative 0.0199 0.1001 0.5916
Leishmania major histone deacetylase, putative 0.0282 0.1458 0.8354
Loa Loa (eye worm) TYRA-2 protein 0.011 0.0505 0.0884
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0042 0.0027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0226 0.1146 0.2002
Trypanosoma cruzi histone deacetylase 1, putative 0.0323 0.1687 0.9669
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0019 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0965 0.5237 0.5235
Echinococcus multilocularis jumonji domain containing protein 0.0035 0.0091 0.0088
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0065 0.0257 0.0254
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0228 0.116 0.3566
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Trypanosoma brucei histone deacetylase 1 0.0323 0.1687 0.9669
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Plasmodium vivax histone deacetylase, putative 0.0282 0.1458 0.4488
Giardia lamblia NADPH oxidoreductase, putative 0.0085 0.0366 0.214
Schistosoma mansoni lamin 0.0043 0.0134 0.0134
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0121 0.0659
Echinococcus multilocularis GPCR, family 2 0.0159 0.0775 0.0773
Trypanosoma brucei histone deacetylase 3 0.0282 0.1458 0.8354
Loa Loa (eye worm) hypothetical protein 0.1052 0.5717 1
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Mycobacterium ulcerans hypothetical protein 0.0074 0.0305 0.0304
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0967
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0033 0.003
Echinococcus granulosus tachykinin peptides receptor 99D 0.011 0.0505 0.0502
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0121 0.011
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0438 0.2483
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Brugia malayi neuropeptide F receptor 0.011 0.0505 0.0882
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0092 0.0438
Schistosoma mansoni hypothetical protein 0.0159 0.0775 0.0775
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0159 0.0775 0.1356
Trypanosoma brucei Carboxypeptidase-like protein 0.002 0.0007 0.0004
Echinococcus granulosus histone lysine methyltransferase setb 0.0042 0.0129 0.0126
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus multilocularis alpha 1A adrenergic receptor 0.011 0.0505 0.0502
Onchocerca volvulus 0.011 0.0505 0.0873
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0226 0.1146 0.1143
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Brugia malayi gonadotropin-releasing hormone receptor 2 0.011 0.0505 0.0882
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0018 0.0018
Brugia malayi Endoplasmin precursor 0.0098 0.0438 0.0765
Trypanosoma brucei unspecified product 0.0029 0.0056 0.0283
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0121 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0092 0.0405 0.0393
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0228 0.116 0.1157
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0085 0.0149
Loa Loa (eye worm) carboxylesterase 0.0022 0.0018 0.0032
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0179 0.0885 0.0882
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0037 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0236 0.1202 0.2102
Schistosoma mansoni DNA polymerase eta 0.0029 0.0056 0.0056
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.4523
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0179 0.0885 0.0882
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0305 0.0304
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0042 0.0209
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0172 0.0849 0.0876
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0774 0.418 0.4378
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0085 0.0366 0.214
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0092 0.0158
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0129 0.0119
Echinococcus granulosus sodium and chloride dependent glycine 0.0179 0.0885 0.0882
Trypanosoma brucei DNA polymerase eta, putative 0.0029 0.0056 0.0283
Schistosoma mansoni lipoxygenase 0.028 0.1445 0.1445
Loa Loa (eye worm) hypothetical protein 0.0343 0.1795 0.314
Schistosoma mansoni histone deacetylase 0.0323 0.1687 0.1687
Mycobacterium leprae Probable lipase LipE 0.0074 0.0305 0.0288
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0043 0.0134 0.0234
Loa Loa (eye worm) solute carrier family 6 member 4 0.1052 0.5717 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0081 0.0343 0.06
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0016 0.0028
Echinococcus granulosus 7TM GPCR rhodopsin 0.011 0.0505 0.0502
Loa Loa (eye worm) acetylcholine receptor protein 0.0109 0.0502 0.0878
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.002 0.0007 0.0004
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0079 0.0332 0.0329
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0018 0.0018
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Treponema pallidum sodium- and chloride- dependent transporter 0.1052 0.5717 0.5999
Schistosoma mansoni neuropeptide f receptor 76f 0.011 0.0505 0.0505
Echinococcus multilocularis smad 0.0034 0.0085 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0254 0.1301 0.1301
Toxoplasma gondii flagellar/basal body protein 0.002 0.0007 0.0003
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0134 0.0234
Brugia malayi MH2 domain containing protein 0.05 0.2664 0.4659
Loa Loa (eye worm) melatonin receptor type 1A 0.011 0.0505 0.0884
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Toxoplasma gondii HEAT repeat-containing protein 0.0075 0.0314 0.1582
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Schistosoma mansoni amine GPCR 0.011 0.0505 0.0505
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0092 0.0507
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0085 0.0082
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Brugia malayi histone deacetylase 3 (HD3) 0.0323 0.1687 0.2949
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0207 0.1041 0.1038
Brugia malayi Carboxylesterase family protein 0.0022 0.0018 0.003
Echinococcus granulosus GPCR family 2 0.0159 0.0775 0.0773
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0207 0.1041 0.5327
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0226 0.1146 0.1143
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0305 0.1716
Leishmania major importin beta-1 subunit, putative 0.0061 0.0235 0.1312
Schistosoma mansoni hypothetical protein 0.011 0.0505 0.0505
Trypanosoma cruzi histone deacetylase, putative 0.0282 0.1458 0.8354
Mycobacterium tuberculosis Probable oxidoreductase 0.0191 0.0955 0.0988
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.011 0.0505 0.0502
Loa Loa (eye worm) histone deacetylase 11 0.0258 0.1324 0.2316
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0305 0.0302
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0042 0.0027
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0226 0.1146 0.1143
Echinococcus multilocularis histone deacetylase 6 0.0282 0.1458 0.1455
Schistosoma mansoni amine GPCR 0.011 0.0505 0.0505
Echinococcus granulosus cpg binding protein 0.0079 0.0336 0.0333
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi Carboxypeptidase A2 precursor 0.002 0.0007 0.001
Loa Loa (eye worm) glutathione reductase 0.0075 0.0314 0.055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.011 0.0505 0.0502
Brugia malayi hypothetical protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Schistosoma mansoni gliotactin 0.0022 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0146 0.0704 0.3589
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0092 0.0089
Brugia malayi Raf kinase 0.0137 0.0656 0.1146
Echinococcus granulosus BC026374 protein S09 family 0.0022 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0121 0.011
Echinococcus multilocularis snurportin 1 0.0804 0.4346 0.4345
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0121 0.011
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0254 0.1301 0.1301
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.0973 0.0973
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Loa Loa (eye worm) RNA binding protein 0.0193 0.0967 0.1691
Loa Loa (eye worm) hypothetical protein 0.0054 0.0196 0.0343
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trypanosoma cruzi histone deacetylase 1, putative 0.0323 0.1687 0.9669
Loa Loa (eye worm) hypothetical protein 0.0065 0.0255 0.0446
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0077 0.0325 0.0322
Echinococcus granulosus cytosolic carboxypeptidase 1 0.002 0.0007 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0238 0.0235
Brugia malayi Dopamine receptor protein 1 0.011 0.0505 0.0882
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Schistosoma mansoni alpha-glucosidase 0.0136 0.0652 0.0652
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Brugia malayi hypothetical protein 0.0179 0.0885 0.1546
Echinococcus multilocularis expressed protein 0.0035 0.0093 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0032 0.0145
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0026 0.0041 0.0177
Schistosoma mansoni bromodomain containing protein 0.0065 0.0255 0.0255
Echinococcus granulosus hypothetical protein 0.011 0.0505 0.0502
Echinococcus multilocularis g-protein coupled receptor 0.011 0.0505 0.0502
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Schistosoma mansoni RAR-like nuclear receptor 0.0037 0.0099 0.0099
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0032 0.0129
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Plasmodium vivax histone deacetylase 2, putative 0.0282 0.1458 0.4488
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0505 0.0505
Trichomonas vaginalis importin beta-1, putative 0.0061 0.0235 0.136
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0179 0.0885 0.0885
Plasmodium vivax thioredoxin reductase, putative 0.0075 0.0314 0.0952
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0238 0.0235
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0004 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0071
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.003 0.0064 0.0294
Loa Loa (eye worm) hypothetical protein 0.0137 0.0654 0.1145
Trypanosoma cruzi cytochrome P450, putative 0.007 0.0286 0.1608
Giardia lamblia DINP protein human, muc B family 0.0029 0.0056 0.0292
Echinococcus multilocularis neuropeptide receptor 0.011 0.0505 0.0502
Giardia lamblia Nuclear ATP/GTP-binding protein 0.002 0.0007 0.0003
Mycobacterium tuberculosis Conserved protein 0.0074 0.0305 0.0304
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.011 0.0505 0.0502
Echinococcus granulosus dro:myosuppressin receptor 0.011 0.0505 0.0502
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0036 0.006
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0226 0.1146 0.1143
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Schistosoma mansoni neurotransmitter gated ion channel 0.0109 0.0502 0.0502
Schistosoma mansoni myosin xvIII 0.011 0.0505 0.0505
Trichomonas vaginalis endoplasmin, putative 0.0071 0.029 0.1687
Entamoeba histolytica hypothetical protein 0.0116 0.0541 0.3181
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0037 0.0099 0.0171
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0108 0.0523
Echinococcus granulosus FTZ F1 alpha 0.0037 0.0099 0.0096
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylenolpyruvoylglucosamine reductase 0.174 0.9526 1
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0042 0.0209
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0121 0.011
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0024 0.0032 0.0029
Giardia lamblia NADPH oxidoreductase, putative 0.0085 0.0366 0.214
Brugia malayi heat shock protein 90 0.0098 0.0438 0.0765
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0099 0.0172
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0056 0.0283
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0092 0.0487
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Echinococcus multilocularis zinc finger protein 0.0025 0.0037 0.0034
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Brugia malayi Cytochrome P450 family protein 0.0131 0.0624 0.1089
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0109 0.0502 0.0878
Onchocerca volvulus 0.0074 0.0305 0.0522
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.011 0.0505 0.0502
Entamoeba histolytica hypothetical protein 0.0024 0.0032 0.0149
Loa Loa (eye worm) hypothetical protein 0.077 0.4159 0.7275
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0286 0.0501
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Schistosoma mansoni smad 0.0034 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0333 0.1741 0.1741
Brugia malayi ImpB/MucB/SamB family protein 0.0029 0.0056 0.0095
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0194 0.0973 0.1006
Loa Loa (eye worm) hypothetical protein 0.0207 0.1041 0.1821
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0099 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0305 0.1719
Brugia malayi Pre-SET motif family protein 0.0175 0.0868 0.1516
Plasmodium vivax heat shock protein, putative 0.0371 0.1949 0.6005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0016 0.0013
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0073 0.0302 0.1701
Schistosoma mansoni intermediate filament proteins 0.0043 0.0134 0.0134
Loa Loa (eye worm) beta-lactamase 0.0074 0.0305 0.0534
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0037 0.0099 0.0173
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0085 0.0085
Echinococcus granulosus peregrin 0.0031 0.0067 0.0064
Echinococcus granulosus intermediate filament protein 0.0043 0.0134 0.0131
Schistosoma mansoni heat shock protein 0.0065 0.0257 0.0257
Giardia lamblia Grp94/Hsp90 0.0092 0.0405 0.2372
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.011 0.0505 0.0502
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0061 0.0235 0.136
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.0097
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0226 0.1146 0.1143
Echinococcus granulosus expressed protein 0.0306 0.1588 0.1585
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.011 0.0505 0.0882
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0179 0.0885 0.0885
Schistosoma mansoni transcription factor LCR-F1 0.0049 0.0171 0.0171
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0021 0.0014 0.0046
Onchocerca volvulus 0.0116 0.0538 0.093
Echinococcus granulosus glycine receptor subunit beta 0.0226 0.1146 0.1143
Echinococcus multilocularis musashi 0.0043 0.0134 0.0131
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0032 0.0141
Toxoplasma gondii zinc carboxypeptidase, putative 0.002 0.0007 0.0003
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.011 0.0505 0.0884
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0024 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus multilocularis fmrfamide receptor 0.011 0.0505 0.0502
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0774 0.0772
Schistosoma mansoni endoplasmin 0.0098 0.0438 0.0438
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0121 0.011
Onchocerca volvulus 0.0022 0.0018 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.013 0.0614 0.1074
Echinococcus multilocularis somatostatin receptor 0.011 0.0505 0.0502
Echinococcus granulosus neuroligin 0.0022 0.0018 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.011 0.0505 0.0884
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0774 0.1353
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0121 0.011
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0121 0.011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0042 0.0027
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.01 0.045 0.137
Echinococcus granulosus PHD finger protein rhinoceros 0.0025 0.0036 0.0033
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0207 0.1041 0.3199
Entamoeba histolytica histone deacetylase, putative 0.0323 0.1687 1
Onchocerca volvulus 0.0116 0.0541 0.0935
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0036 0.0064
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0092 0.0507
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Schistosoma mansoni histone deacetylase 0.0323 0.1687 0.1687
Brugia malayi larval opioid receptor 0.011 0.0505 0.0882
Echinococcus granulosus snurportin 1 0.0804 0.4346 0.4345
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0967
Schistosoma mansoni steroid hormone receptor ad4bp 0.0037 0.0099 0.0099
Echinococcus multilocularis G-protein coupled receptor, putative 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0065 0.0257 0.0437
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0226 0.1146 0.2004
Toxoplasma gondii histone deacetylase HDAC5 0.0137 0.0654 0.3336
Trypanosoma cruzi DNA polymerase eta, putative 0.0029 0.0056 0.028
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0022 0.0018 0.0015
Onchocerca volvulus 0.0091 0.0401 0.0689
Loa Loa (eye worm) hypothetical protein 0.003 0.0062 0.0109
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0081 0.014
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0121 0.011
Onchocerca volvulus 0.011 0.0505 0.0873
Onchocerca volvulus 0.0091 0.0401 0.0689
Brugia malayi Cation transporter family protein 0.0226 0.1146 0.2002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0042 0.0108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0085 0.0366 0.214
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0026 0.0041 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Loa Loa (eye worm) heat shock protein 90 0.0098 0.0438 0.0767
Schistosoma mansoni ran 0.0055 0.0204 0.0204
Trypanosoma brucei importin beta-1 subunit, putative 0.0075 0.0314 0.1769
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0109 0.0502 0.0499
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.011 0.0505 0.0505
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0658 0.0655
Onchocerca volvulus 0.0199 0.1001 0.174
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0032 0.0016
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0305 0.0534
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0035 0.0093 0.0163
Onchocerca volvulus 0.0074 0.0305 0.0522
Loa Loa (eye worm) TAR-binding protein 0.0193 0.0967 0.1691
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Onchocerca volvulus 0.0092 0.0404 0.0696
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.4523
Loa Loa (eye worm) CYP4Cod1 0.007 0.0286 0.0501
Schistosoma mansoni smad1 5 8 and 0.0034 0.0085 0.0085
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0121 0.011
Brugia malayi PHD-finger family protein 0.0025 0.0036 0.0062
Schistosoma mansoni inositol transporter 0.0026 0.0041 0.0041
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0064 0.0109
Loa Loa (eye worm) hypothetical protein 0.0145 0.0701 0.1226
Echinococcus granulosus neuropeptide Y receptor 0.011 0.0505 0.0502
Onchocerca volvulus 0.0116 0.0541 0.0935
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.0967 0.1691
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0238 0.0235
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.011 0.0505 0.0502
Brugia malayi nuclear receptor NHR-88 0.0037 0.0099 0.0171
Trichomonas vaginalis phosphofructokinase, putative 0.0073 0.0302 0.1762
Onchocerca volvulus 0.011 0.0505 0.0873
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0079 0.0332 0.0329
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0037 0.0099 0.0173
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0073 0.0302 0.0311
Onchocerca volvulus 0.0035 0.0093 0.0151
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0438 0.2483
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0298 0.1734
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus serotonin receptor 0.011 0.0505 0.0502
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Chlamydia trachomatis phenylalanine--tRNA ligase subunit beta 0.0047 0.0158 0.0159
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.011 0.0505 0.0882
Brugia malayi Thioredoxin reductase 0.0075 0.0314 0.0548
Echinococcus multilocularis neuropeptide receptor 0.011 0.0505 0.0502
Schistosoma mansoni hypothetical protein 0.011 0.0505 0.0505
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0121 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0024 0.0032 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0121 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0085 0.0082
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0123 0.0579 0.0592
Entamoeba histolytica hypothetical protein 0.0049 0.0171 0.0977
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0092 0.0405 0.0409
Loa Loa (eye worm) hypothetical protein 0.0075 0.0314 0.0549
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0175 0.0868 0.1518
Plasmodium falciparum glutathione reductase 0.0075 0.0314 0.1585
Onchocerca volvulus 0.011 0.0505 0.0873
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.0973 0.1006
Echinococcus multilocularis neuroligin 0.0022 0.0018 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0226 0.1146 0.1143
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Trypanosoma brucei heat shock protein 84, putative 0.0065 0.0257 0.144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0007
Mycobacterium leprae putative cytochrome p450 0.004 0.0121 0.0094
Echinococcus multilocularis neuropeptide FF receptor 2 0.011 0.0505 0.0502
Trypanosoma cruzi histone deacetylase, putative 0.0282 0.1458 0.8354
Loa Loa (eye worm) neuropeptide F receptor 0.011 0.0505 0.0884
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Echinococcus granulosus acetylcholinesterase 0.013 0.0614 0.0611
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0123 0.0579 0.0592
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.0973 0.1006
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0207 0.1041 0.5953
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0121 0.011
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0196 0.0193
Schistosoma mansoni loxhd1 0.0091 0.0401 0.0401
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.0021 0.0014 0.0046
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.1548
Brugia malayi Latrophilin receptor protein 2 0.0159 0.0775 0.1355
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0092 0.016
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0228 0.116 0.2029
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Plasmodium vivax multidomain scavenger receptor, putative 0.0091 0.0401 0.1218
Echinococcus multilocularis cytosolic carboxypeptidase protein 5 0.002 0.0007 0.0004
Brugia malayi nuclear receptor RXR 0.0019 0.0004 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.05 0.2664 0.466
Trypanosoma brucei trypanothione reductase 0.0075 0.0314 0.1772
Echinococcus granulosus dnaJ subfamily B 0.0657 0.3532 0.353
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0226 0.1146 0.2004
Leishmania major heat shock protein, putative 0.0065 0.0257 0.1437
Brugia malayi AKH receptor 0.011 0.0505 0.0882
Echinococcus multilocularis neuropeptide receptor A26 0.011 0.0505 0.0502
Trichomonas vaginalis phosphofructokinase, putative 0.0073 0.0302 0.1762
Echinococcus granulosus para nitrobenzyl esterase 0.0022 0.0018 0.0015
Plasmodium falciparum thioredoxin reductase 0.0026 0.0042 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0121 0.011
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0039
Schistosoma mansoni hypothetical protein 0.0035 0.0093 0.0093
Toxoplasma gondii hypothetical protein 0.0179 0.0885 0.4523
Echinococcus multilocularis dnaJ subfamily B 0.0657 0.3532 0.353
Schistosoma mansoni acetylcholine receptor-related 0.0109 0.0502 0.0502
Echinococcus granulosus glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0444 0.2352 0.2349
Plasmodium vivax histone deacetylase, putative 0.0258 0.1324 0.4074
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0121 0.011
Toxoplasma gondii histone deacetylase HDAC1 0.0282 0.1458 0.7474
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0254 0.1301 0.2274
Loa Loa (eye worm) cytochrome P450 family protein 0.0131 0.0624 0.1091
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0109 0.0502 0.0499
Brugia malayi sulfakinin receptor protein 0.011 0.0505 0.0882
Echinococcus multilocularis raf serine:threonine protein kinase 0.0142 0.0683 0.0681
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0016 0.0013
Loa Loa (eye worm) carboxylesterase 0.013 0.0614 0.1074
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0116 0.0541 0.0944
Brugia malayi Carboxylesterase family protein 0.013 0.0614 0.1072
Echinococcus granulosus dna polymerase kappa 0.0029 0.0056 0.0053
Mycobacterium tuberculosis Conserved hypothetical protein 0.0029 0.0056 0.0042
Echinococcus multilocularis Smad4 0.0034 0.0085 0.0082
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0019 0.0034
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0084 0.036 0.0357
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.003 0.0027
Brugia malayi hypothetical protein 0.0109 0.0502 0.0876
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0121 0.011
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0056
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0179 0.0885 0.0882
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Loa Loa (eye worm) hypothetical protein 0.1052 0.5717 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0298 0.1734
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0037 0.0099 0.0171
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0502 0.2673 0.4676
Echinococcus multilocularis sex peptide receptor 0.011 0.0505 0.0502
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0049 0.0171 0.0168
Onchocerca volvulus 0.0116 0.0538 0.093
Echinococcus multilocularis neuropeptide Y receptor 0.011 0.0505 0.0502
Entamoeba histolytica phosphofructokinase, putative 0.0073 0.0302 0.1762
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0099 0.0096
Brugia malayi Steroid receptor seven-up type 2 0.0037 0.0099 0.0171
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0196 0.0193
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni coup transcription factor 0.0037 0.0099 0.0099
Schistosoma mansoni cytochrome P450 0.004 0.0121 0.0121
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0073 0.0302 0.0301
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0226
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus L aminoadipate semialdehyde 0.0024 0.0032 0.0029
Schistosoma mansoni hypothetical protein 0.0025 0.0036 0.0036
Echinococcus multilocularis histone deacetylase 6 0.0282 0.1458 0.1455
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0025 0.0036 0.0036
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) serotonin transporter b 0.1052 0.5717 1
Echinococcus multilocularis cpg binding protein 0.0079 0.0336 0.0333
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0226 0.1146 0.2002
Echinococcus multilocularis high affinity choline transporter 1 0.0236 0.1202 0.1199
Loa Loa (eye worm) MBCTL1 0.0062 0.0238 0.0416
Trypanosoma brucei histone deacetylase 2 0.0137 0.0654 0.3729
Trypanosoma brucei DNA polymerase IV, putative 0.0029 0.0056 0.0283
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0121 0.011
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.0967 0.1689
Echinococcus granulosus Polycystic kidney disease protein 0.0091 0.0401 0.0398
Trypanosoma cruzi histone deacetylase, putative 0.0282 0.1458 0.8354
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi N-terminal motif family protein 0.014 0.0671 0.1172
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni hypothetical protein 0.0745 0.4021 0.4021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0965 0.5237 0.5235
Toxoplasma gondii aldehyde dehydrogenase 0.0194 0.0973 0.4974
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0123 0.0579 0.2946
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Echinococcus granulosus neuropeptide s receptor 0.011 0.0505 0.0502
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0108 0.0605
Schistosoma mansoni cpg binding protein 0.0079 0.0336 0.0336
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0213 0.1189
Onchocerca volvulus 0.011 0.0505 0.0873
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0092 0.0405 0.0409
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Trypanosoma cruzi heat shock protein, putative 0.0065 0.0257 0.1437
Treponema pallidum heat shock protein 90 0.0092 0.0405 0.0419
Echinococcus granulosus neuropeptide receptor 0.011 0.0505 0.0502
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0092 0.0089
Echinococcus multilocularis g protein coupled receptor 0.011 0.0505 0.0502
Leishmania major histone deacetylase, putative 0.0282 0.1458 0.8354
Echinococcus granulosus endoplasmin 0.0092 0.0405 0.0402
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0109 0.0502 0.0499
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0037 0.0099 0.0171
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Brugia malayi 6-phosphofructokinase 0.0073 0.0302 0.0527
Plasmodium falciparum heat shock protein 90 0.0098 0.0438 0.2223
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0092 0.0507
Echinococcus multilocularis endoplasmin 0.0092 0.0405 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0037 0.0099 0.0171
Trichomonas vaginalis phosphofructokinase, putative 0.0073 0.0302 0.1762
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.011 0.0505 0.0502
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0438 0.2486
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0025 0.0036 0.0036
Schistosoma mansoni Smad4 0.0034 0.0085 0.0085
Onchocerca volvulus 0.1052 0.5717 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0003 0.0003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0036 0.0033
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0077 0.0325 0.0567
Brugia malayi latrophilin 2 splice variant baaae 0.0343 0.1795 0.3138
Echinococcus multilocularis RUN 0.0091 0.0401 0.0398
Schistosoma mansoni terminal deoxycytidyl transferase 0.0029 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0804 0.4346 0.4346
Echinococcus multilocularis lamin dm0 0.0043 0.0134 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0363 0.0363
Echinococcus granulosus histone deacetylase 7 0.0282 0.1458 0.1455
Schistosoma mansoni sodium/chloride dependent transporter 0.0179 0.0886 0.0886
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Brugia malayi hypothetical protein 0.0027 0.0047 0.0081
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0029 0.0056 0.0042
Echinococcus multilocularis histone deacetylase 3 0.0323 0.1687 0.1684
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0207 0.1041 0.1041
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0323 0.1687 1
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Echinococcus granulosus zinc finger protein 0.0025 0.0037 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Echinococcus multilocularis serotonin receptor 0.011 0.0505 0.0502
Brugia malayi Serotonin/octopamine receptor family protein 7 0.011 0.0505 0.0882
Loa Loa (eye worm) histone methyltransferase 0.0024 0.0028 0.0049
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0226 0.1146 0.1146
Echinococcus multilocularis orexin receptor type 2 0.011 0.0505 0.0502
Brugia malayi ORL1-like opioid receptor 0.011 0.0505 0.0882
Schistosoma mansoni biogenic amine (5HT) receptor 0.011 0.0505 0.0505
Brugia malayi Histone deacetylase family protein 0.0282 0.1458 0.2549
Echinococcus granulosus voltage gated potassium channel 0.0024 0.0032 0.0029
Loa Loa (eye worm) cytochrome P450 0.004 0.0121 0.0211
Echinococcus multilocularis lipoxygenase domain containing protein 0.0091 0.0401 0.0398
Trypanosoma cruzi heat shock protein 85, putative 0.0084 0.036 0.2033
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0003 0.0003
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0035 0.0093 0.0161
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0502 0.2673 0.4676
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.011 0.0505 0.0502
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0471 0.2505 0.2617
Schistosoma mansoni zinc finger protein 0.0025 0.0037 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0121 0.011
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0109 0.0502 0.0878
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0238 0.0235
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0305 0.1777
Echinococcus multilocularis Polycystic kidney disease protein 0.0091 0.0401 0.0398
Echinococcus granulosus histone deacetylase 1 0.0323 0.1687 0.1684
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Brugia malayi GnHR receptor homolog 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Schistosoma mansoni neurotransmitter gated ion channel 0.0116 0.0541 0.0541
Loa Loa (eye worm) zinc carboxypeptidase 0.002 0.0007 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0042 0.0181
Brugia malayi beta-lactamase 0.0074 0.0305 0.0532
Schistosoma mansoni biogenic amine receptor 0.011 0.0505 0.0505
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0047 0.0158 0.0149
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0042 0.0199
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0016 0.0029
Leishmania major histone deacetylase, putative 0.0323 0.1687 0.9669
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0037 0.0099 0.0096
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0064 0.0109
Trichomonas vaginalis esterase, putative 0.0074 0.0305 0.1777
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0037 0.0099 0.0161
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi hypothetical protein 0.0098 0.0441 0.077
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.002
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0226 0.1146 0.2002
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Mycobacterium tuberculosis Conserved protein 0.0074 0.0305 0.0304
Echinococcus multilocularis nAChR subunit 0.0116 0.0541 0.0538
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0305 0.0305
Onchocerca volvulus 0.0022 0.0018 0.002
Schistosoma mansoni family M14 non-peptidase homologue (M14 family) 0.002 0.0007 0.0007
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0207 0.1041 0.1038
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0305 0.0304
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0093 0.0161
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0226 0.1146 0.2002
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0116 0.0538 0.0535
Loa Loa (eye worm) G-protein coupled receptor 0.011 0.0505 0.0884
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0305 0.0532
Loa Loa (eye worm) MH2 domain-containing protein 0.05 0.2664 0.466
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Echinococcus granulosus heat shock protein 90 0.0098 0.0438 0.0435
Loa Loa (eye worm) acetyltransferase 0.0144 0.0692 0.1211
Onchocerca volvulus 0.0027 0.0044 0.0064
Onchocerca volvulus 0.0179 0.0885 0.1538
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0073 0.0302 0.1704
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0083 0.0354 0.0351
Onchocerca volvulus 0.0022 0.0018 0.002
Loa Loa (eye worm) histone deacetylase 0.0282 0.1458 0.255
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0024 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Entamoeba histolytica modulator of drug activity B homolog, putative 0.0021 0.0014 0.0046
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0226 0.1146 0.1143
Trypanosoma cruzi trypanothione reductase, putative 0.0075 0.0314 0.1769
Echinococcus multilocularis L aminoadipate semialdehyde 0.0024 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.0091 0.0401 0.0701
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.011 0.0505 0.0505
Schistosoma mansoni growth hormone secretagogue receptor 0.011 0.0505 0.0505
Schistosoma mansoni opsin-like receptor 0.011 0.0505 0.0505
Echinococcus granulosus geminin 0.0745 0.4021 0.4019
Schistosoma mansoni peptidase 0.002 0.0007 0.0007
Leishmania major cytochrome p450-like protein 0.007 0.0286 0.1608
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0049 0.0049
Schistosoma mansoni protease m14 carboxypeptidase 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0121 0.011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0502 0.2673 0.4675
Echinococcus granulosus thioredoxin glutathione reductase 0.0075 0.0314 0.0311
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0042 0.0181
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0774 0.0772
Onchocerca volvulus Huntingtin homolog 0.0098 0.0441 0.076
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Schistosoma mansoni retinoic acid receptor RXR 0.0037 0.0099 0.0099
Schistosoma mansoni rab6-interacting 0.0091 0.0401 0.0401
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0077 0.0325 0.0322
Toxoplasma gondii thioredoxin reductase 0.0075 0.0314 0.1585
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0026 0.0041 0.0038
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0016 0.0055
Leishmania major ATP-dependent phosphofructokinase 0.0073 0.0302 0.1701
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0023 0.0024 0.0042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.011 0.0505 0.0505
Brugia malayi G-protein coupled receptor 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0027 0.0044 0.0192
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0032 0.0076 0.0073
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0196 0.0193
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0196 0.0196
Echinococcus granulosus neuropeptides capa receptor 0.011 0.0505 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Schistosoma mansoni nAChR subunit 0.0226 0.1146 0.1146
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0055 0.0204 0.0356
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0305 0.0304
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Onchocerca volvulus 0.0037 0.0099 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0121 0.011
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0179 0.0885 0.0882
Brugia malayi hypothetical protein 0.0109 0.0502 0.0876
Brugia malayi Cation transporter family protein 0.0226 0.1146 0.2002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.118 0.6426 0.6425
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Brugia malayi hypothetical protein 0.0091 0.0401 0.0699
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0116 0.0538 0.0535
Leishmania major cytochrome p450-like protein 0.004 0.0121 0.0656
Echinococcus multilocularis BC026374 protein (S09 family) 0.0022 0.0018 0.0015
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0109 0.0502 0.0499
Onchocerca volvulus Protein ultraspiracle homolog 0.0037 0.0099 0.0161
Plasmodium falciparum amino acid transporter, putative 0.0179 0.0885 0.4523
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0037 0.0099 0.0096
Echinococcus granulosus lipoxygenase domain containing protein 0.0091 0.0401 0.0398
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0179 0.0885 0.0923
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0056 0.028
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0194 0.0973 0.5559
Loa Loa (eye worm) hypothetical protein 0.013 0.0614 0.1074
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0109 0.0502 0.0499
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0139 0.0789
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0016 0.0052
Onchocerca volvulus 0.0226 0.1146 0.1994
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0159 0.0775 0.0773
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0092 0.0507
Leishmania major GTP-binding protein, putative 0.0055 0.0204 0.1132
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0604 0.3241 1
Loa Loa (eye worm) hypothetical protein 0.0911 0.494 0.8641
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0035 0.0093 0.0093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0036 0.0166
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0238 0.0235
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0037 0.0099 0.0099
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.4523
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.0774 0.418 0.4378
Echinococcus granulosus Smad4 0.0034 0.0085 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0099 0.0096
Brugia malayi neuropeptide F receptor 0.011 0.0505 0.0882
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0692 0.0692
Echinococcus multilocularis dro:myosuppressin receptor 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0098 0.0441 0.0772
Loa Loa (eye worm) 6-phosphofructokinase 0.0073 0.0302 0.0529
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 0.1744 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0323 0.1687 1
Brugia malayi MH2 domain containing protein 0.0034 0.0085 0.0147
Loa Loa (eye worm) zinc carboxypeptidase 0.002 0.0007 0.0012
Schistosoma mansoni adenoreceptor 0.011 0.0505 0.0505
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Echinococcus granulosus nAChR subunit 0.0116 0.0541 0.0538
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0037 0.0099 0.0173
Echinococcus multilocularis lipoxygenase domain containing protein 0.0091 0.0401 0.0398
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0157 0.0862
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.1546
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0129 0.0728
Schistosoma mansoni sodium/chloride dependent transporter 0.0179 0.0885 0.0885
Schistosoma mansoni carboxypeptidase N (M14 family) 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0129 0.0126
Onchocerca volvulus 0.0226 0.1146 0.1994
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Echinococcus granulosus heat shock protein 0.0098 0.0438 0.0435
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0226 0.1146 0.2004
Onchocerca volvulus 0.0226 0.1146 0.1994
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0029 0.0056 0.0292
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.0973 0.1006
Schistosoma mansoni lamin 0.0043 0.0134 0.0134
Trypanosoma cruzi polo-like protein kinase, putative 0.0034 0.0084 0.0444
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0121 0.0656
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0172 0.0849 0.0861
Brugia malayi Pre-SET motif family protein 0.0027 0.0044 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0056 0.028
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0121 0.011
Brugia malayi MH1 domain containing protein 0.0034 0.0085 0.0147
Echinococcus granulosus heat shock protein 90 0.0084 0.036 0.0357
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0007
Echinococcus multilocularis FTZ F1 alpha 0.0037 0.0099 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Toxoplasma gondii hypothetical protein 0.0054 0.0195 0.097
Echinococcus granulosus thyrotropin releasing hormone receptor 0.011 0.0505 0.0502
Onchocerca volvulus 0.0109 0.0502 0.0866
Plasmodium vivax heat shock protein 86, putative 0.0098 0.0438 0.1335
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0305 0.0304
Echinococcus multilocularis geminin 0.0745 0.4021 0.4019
Schistosoma mansoni heat shock protein 0.0098 0.0438 0.0438
Loa Loa (eye worm) Smad1 0.0034 0.0085 0.0149
Echinococcus multilocularis peregrin 0.0031 0.0067 0.0064
Brugia malayi Importin beta-1 subunit 0.0075 0.0314 0.0547
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni peptidase 0.002 0.0007 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0004 0.0004
Echinococcus granulosus serotonin transporter 0.1052 0.5717 0.5716
Onchocerca volvulus Alhambra homolog 0.0025 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0323 0.1687 0.295
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.011 0.0505 0.0873
Echinococcus multilocularis tachykinin peptides receptor 99D 0.011 0.0505 0.0502
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0092 0.0405 0.2292
Loa Loa (eye worm) ACC-1 protein 0.0226 0.1146 0.2004
Schistosoma mansoni sodium/chloride dependent transporter 0.1052 0.5717 0.5717
Echinococcus multilocularis 0.004 0.0121 0.0118
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0121 0.011
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.011 0.0505 0.0505
Giardia lamblia Kinase, PLK 0.0034 0.0084 0.0462
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.011 0.0505 0.0505
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0228 0.116 0.5939
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0226 0.1146 0.1143
Schistosoma mansoni metallocarboxypeptidase D peptidase unit 2 (M14 family) 0.002 0.0007 0.0007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0104 0.0077
Schistosoma mansoni ap endonuclease 0.0022 0.0016 0.0016
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.011 0.0505 0.0502
Entamoeba histolytica Ran family GTPase 0.0055 0.0204 0.1174
Brugia malayi histone deacetylase 1 (HD1) 0.0323 0.1687 0.2949
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni ap endonuclease 0.0022 0.0016 0.0016
Brugia malayi G protein-coupled receptor F59B2.13 0.011 0.0505 0.0882
Schistosoma mansoni histone deacetylase 4 5 0.0282 0.1458 0.1458
Echinococcus multilocularis tar DNA binding protein 0.0193 0.0967 0.0964
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0228 0.116 0.2027
Schistosoma mansoni importin beta-1 0.0075 0.0314 0.0314
Echinococcus granulosus smad 0.0034 0.0085 0.0082
Brugia malayi PHD-finger family protein 0.003 0.0064 0.0109
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0129 0.0701
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0226 0.1146 0.1143
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0034 0.0084 0.0081
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0228 0.116 0.116
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus multilocularis para nitrobenzyl esterase 0.0022 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Onchocerca volvulus 0.0022 0.0018 0.002
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0123 0.0579 0.1769
Brugia malayi hypothetical protein 0.0109 0.0502 0.0876
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0305 0.0304
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0774 0.1355
Trichomonas vaginalis heat shock protein, putative 0.0084 0.036 0.2105
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0061 0.0235 0.136
Schistosoma mansoni opsin-like receptor 0.011 0.0505 0.0505
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.077 0.4159 0.7274
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0064 0.0177
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0035 0.0093 0.0447
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0305 0.1777
Leishmania major DNA polymerase kappa, putative 0.0029 0.0056 0.028
Echinococcus granulosus fmrfamide receptor 0.011 0.0505 0.0502
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0036 0.0093
Schistosoma mansoni hypothetical protein 0.0091 0.0401 0.0401
Echinococcus granulosus sex peptide receptor 0.011 0.0505 0.0502
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.014 0.0671 0.1163
Brugia malayi Serotonin receptor 0.0581 0.311 0.544
Toxoplasma gondii heat shock protein 75, putative 0.0065 0.0257 0.1288
Loa Loa (eye worm) hypothetical protein 0.0096 0.0428 0.0749
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0116 0.0538 0.093
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0022 0.0018 0.0002
Schistosoma mansoni inositol monophosphatase 0.0042 0.0129 0.0129
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0438 0.2483
Onchocerca volvulus Histone deacetylase 10 homolog 0.0137 0.0654 0.1134
Schistosoma mansoni polycystin 1-related 0.0091 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Chlamydia trachomatis UDP-N-acetylenolpyruvoylglucosamine reductase 0.174 0.9526 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.011 0.0505 0.0502
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0226 0.1146 0.1143
Mycobacterium tuberculosis Probable reductase 0.0172 0.0849 0.0876
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0036 0.0166
Brugia malayi MH2 domain containing protein 0.0034 0.0085 0.0147
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0196 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0774 0.0772
Schistosoma mansoni kinase 0.0112 0.0518 0.0518
Schistosoma mansoni neuropeptide F-like receptor 0.011 0.0505 0.0505
Trypanosoma cruzi heat shock protein 90, putative 0.0098 0.0438 0.2483
Brugia malayi excitatory GABA receptor EXP-1A 0.0226 0.1146 0.2002
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0022 0.0018 0.0002
Brugia malayi Histone deacetylase family protein 0.0282 0.1458 0.2549
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0037 0.0099 0.0171
Trichomonas vaginalis ran, putative 0.0055 0.0204 0.1174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0037 0.0099 0.0173
Brugia malayi hypothetical protein 0.0109 0.0502 0.0876
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0039
Onchocerca volvulus 0.0116 0.0538 0.093
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0226 0.1146 0.2002
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0016 0.0057
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0025 0.0036 0.0174
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0004 0.0008
Brugia malayi Sodium:solute symporter family protein 0.0026 0.0041 0.0069
Loa Loa (eye worm) hypothetical protein 0.0062 0.0238 0.0416
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1052 0.5717 0.5717
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0108 0.0605
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0121 0.011
Brugia malayi Cytochrome P450 family protein 0.007 0.0286 0.0499
Onchocerca volvulus 0.0109 0.0502 0.0866
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0238 0.0414
Echinococcus granulosus jumonji domain containing protein 0.0035 0.0091 0.0088
Entamoeba histolytica deoxycytidyl transferase, putative 0.0029 0.0056 0.0292
Plasmodium falciparum glutathione reductase 0.0026 0.0042 0.0181
Trypanosoma cruzi histone deacetylase, putative 0.0137 0.0654 0.3727
Mycobacterium ulcerans beta-lactamase 0.0074 0.0305 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Schistosoma mansoni jumonji domain containing protein 0.0066 0.026 0.026
Schistosoma mansoni alpha-glucosidase 0.0136 0.0652 0.0652
Brugia malayi mbt repeat family protein 0.0054 0.0196 0.0341
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0692 0.0689
Brugia malayi cytochrome P450 0.004 0.0121 0.0209
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0212 0.1221
Brugia malayi RNA, U transporter 1 0.0214 0.1082 0.1891
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0203
Plasmodium vivax hypothetical protein, conserved 0.0179 0.0885 0.2716
Echinococcus multilocularis g protein coupled receptor 0.011 0.0505 0.0502
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0037 0.0099 0.0173
Schistosoma mansoni acetylcholine receptor subunit beta 0.0109 0.0502 0.0502
Toxoplasma gondii PHD-finger domain-containing protein 0.0025 0.0036 0.0154
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0036 0.0169
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0116 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0064 0.025 0.0438
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Echinococcus multilocularis fmrfamide receptor 0.011 0.0505 0.0502
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0207 0.1041 0.5955
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni histone deacetylase 4 5 0.0282 0.1458 0.1458
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Loa Loa (eye worm) inositol-1 0.0042 0.0129 0.0225
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.011 0.0505 0.0505
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0121 0.0589
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0226 0.1146 0.1146
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0121 0.011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0042
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0121 0.011
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0026 0.0041 0.0038
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0018 0.0018
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0207 0.1041 0.6158
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0305 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0967
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0226 0.1146 0.2002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Brugia malayi Carboxylesterase family protein 0.0022 0.0018 0.003
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus granulosus survival motor neuron protein 1 0.0174 0.0858 0.0856
Echinococcus multilocularis glycine receptor subunit beta 0.0226 0.1146 0.1143
Echinococcus granulosus neuropeptide FF receptor 2 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0109 0.0502 0.0876
Onchocerca volvulus 0.0026 0.0041 0.0059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0004 0.0004
Echinococcus multilocularis histone deacetylase 6 0.0282 0.1458 0.1455
Loa Loa (eye worm) thioredoxin reductase 0.0075 0.0314 0.055
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0226 0.1146 0.2002
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus multilocularis histone deacetylase 8 0.0137 0.0654 0.0652
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0196 0.0193
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0055 0.0204 0.0354
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0016 0.0052
Echinococcus multilocularis ecdysone induced protein 78C 0.0037 0.0099 0.0096
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0438 0.257
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0099 0.0096
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0047 0.0158 0.0149
Echinococcus multilocularis lysine specific demethylase 5A 0.0031 0.0066 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0967
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0019 0.0016
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.0774 0.418 0.4384
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0121 0.0118
Echinococcus granulosus histone deacetylase 3 0.0323 0.1687 0.1684
Echinococcus granulosus neuropeptides capa receptor 0.011 0.0505 0.0502
Plasmodium falciparum phenylalanine--tRNA ligase 0.0147 0.071 0.3624
Plasmodium vivax endoplasmin, putative 0.0098 0.0438 0.1335
Brugia malayi hypothetical protein 0.0027 0.0047 0.0081
Echinococcus multilocularis serotonin transporter 0.1052 0.5717 0.5716
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0254 0.1301 0.1299
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Echinococcus granulosus tar DNA binding protein 0.0193 0.0967 0.0964
Toxoplasma gondii heat shock protein HSP90 0.0098 0.0438 0.2223
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0092 0.0507
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0226 0.1146 0.2004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0139 0.0136
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0025 0.0036 0.0174
Brugia malayi putative neuropeptide receptor 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0179 0.0885 0.0882
Echinococcus granulosus lamin dm0 0.0043 0.0134 0.0131
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0226 0.1146 0.2002
Plasmodium falciparum histone deacetylase 1 0.0323 0.1687 0.865
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0092 0.0507
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Echinococcus granulosus orexin receptor type 2 0.011 0.0505 0.0502
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0305 0.0923
Schistosoma mansoni hypothetical protein 0.0159 0.0775 0.0775
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0037 0.0099 0.0171
Echinococcus multilocularis Zinc carboxypeptidase family protein 0.002 0.0007 0.0004
Schistosoma mansoni BC026374 protein (S09 family) 0.0022 0.0018 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.0073 0.0302 0.1762
Onchocerca volvulus 0.0043 0.0134 0.0222
Schistosoma mansoni cpg binding protein 0.0073 0.0304 0.0304
Echinococcus granulosus neuropeptide Y receptor 0.011 0.0505 0.0502
Entamoeba histolytica hypothetical protein 0.0049 0.0171 0.0977
Brugia malayi beta-lactamase family protein 0.0074 0.0305 0.0532
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.011 0.0505 0.0502
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0194 0.0973 0.097
Plasmodium falciparum histone deacetylase, putative 0.0282 0.1458 0.7474
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0159 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0074 0.0305 0.0534
Echinococcus granulosus importin subunit beta 1 0.0075 0.0314 0.0311
Echinococcus multilocularis biogenic amine (5HT) receptor 0.011 0.0505 0.0502
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0116 0.0541 0.0541
Echinococcus granulosus Zinc carboxypeptidase family protein 0.002 0.0007 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0029 0.0056 0.028
Trichomonas vaginalis heat shock protein, putative 0.0071 0.029 0.1687
Schistosoma mansoni neurotransmitter gated ion channel 0.0109 0.0502 0.0502
Trypanosoma cruzi importin beta-1 subunit, putative 0.0061 0.0235 0.1312
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0037 0.0099 0.0096
Echinococcus granulosus G protein coupled receptor 139 0.011 0.0505 0.0502
Toxoplasma gondii histone deacetylase HDAC3 0.0323 0.1687 0.865
Trypanosoma brucei heat shock protein, putative 0.0098 0.0438 0.2486
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0044 0.0044
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0438 0.2486
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0179 0.0885 0.0885
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0025 0.0036 0.0036
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0196 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Echinococcus multilocularis PHD finger protein rhinoceros 0.0025 0.0036 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Mycobacterium ulcerans carboxylesterase, LipT 0.0022 0.0018 0.0002
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0065 0.0257 0.0254
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0092 0.0507
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Leishmania major histone deacetylase, putative 0.0323 0.1687 0.9669
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0157 0.0865
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Schistosoma mansoni lipoxygenase 0.0444 0.2352 0.2352
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0286 0.0501
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0092 0.0487
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0042 0.0209
Schistosoma mansoni neuropeptide receptor 0.011 0.0505 0.0505
Onchocerca volvulus 0.011 0.0505 0.0873
Brugia malayi Bromodomain containing protein 0.0075 0.0314 0.0547
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0042 0.0181
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0159 0.0775 0.0773
Entamoeba histolytica phosphofructokinase, putative 0.0073 0.0302 0.1762
Onchocerca volvulus Bile acid receptor homolog 0.0037 0.0099 0.0161
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0129 0.0728
Toxoplasma gondii PHD-finger domain-containing protein 0.0025 0.0036 0.0154
Brugia malayi Intermediate filament tail domain containing protein 0.0043 0.0134 0.0232
Echinococcus multilocularis 0.002 0.0007 0.0004
Trichomonas vaginalis heat shock protein, putative 0.0098 0.0438 0.257
Mycobacterium tuberculosis Conserved protein 0.0074 0.0305 0.0304
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Loa Loa (eye worm) GABA receptor subunit 0.0116 0.0541 0.0946
Loa Loa (eye worm) hypothetical protein 0.0174 0.0858 0.1501
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0029 0.0056 0.028
Echinococcus multilocularis serotonin receptor 0.011 0.0505 0.0502
Plasmodium falciparum histone deacetylase 2 0.0282 0.1458 0.7474
Plasmodium vivax SET domain protein, putative 0.0027 0.0044 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.0973 0.0973
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.1546
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0218 0.1101 0.1098
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Schistosoma mansoni peptide (allatostatin)-like receptor 0.011 0.0505 0.0505
Trichomonas vaginalis histone deacetylase, putative 0.0323 0.1687 1
Echinococcus granulosus histone deacetylase 8 0.0137 0.0654 0.0652
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0049 0.0171 0.0168
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0203
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0099 0.0096
Plasmodium falciparum LCCL domain-containing protein 0.0091 0.0401 0.2029
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0012
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0226 0.1146 0.2004
Echinococcus multilocularis survival motor neuron protein 1 0.0174 0.0858 0.0856
Brugia malayi Dopamine receptor protein 2 0.011 0.0505 0.0882
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0109 0.0502 0.0876
Echinococcus multilocularis dna polymerase kappa 0.0029 0.0056 0.0053
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Onchocerca volvulus 0.0179 0.0885 0.1538
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Plasmodium falciparum heat shock protein 90, putative 0.0057 0.0212 0.1056
Echinococcus granulosus glycine receptor subunit alpha 1 0.0226 0.1146 0.1143
Trichomonas vaginalis heat shock protein, putative 0.0092 0.0405 0.2372
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0196 0.0343
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0191 0.0955 0.0973
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0116 0.0541 0.0944
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0092 0.0507
Schistosoma mansoni histone deacetylase hda2 0.0137 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus granulosus histone deacetylase 6 0.0282 0.1458 0.1455
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0505 0.0505
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0042 0.0203
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.003 0.0064 0.0064
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0121 0.0656
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus multilocularis neuropeptide s receptor 0.011 0.0505 0.0502
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.011 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0037 0.0099 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Onchocerca volvulus 0.0226 0.1146 0.1994
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0037 0.0099 0.0099
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0157 0.0862
Giardia lamblia PHD finger protein 15 0.0025 0.0036 0.0178
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.013 0.0614 0.0614
Onchocerca volvulus 0.0043 0.0134 0.0222
Entamoeba histolytica hypothetical protein 0.0061 0.0235 0.136
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0129 0.0701
Echinococcus granulosus lipoxygenase domain containing protein 0.0091 0.0401 0.0398
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0129 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0121 0.011
Echinococcus multilocularis acetylcholinesterase 0.013 0.0614 0.0611
Onchocerca volvulus 0.0074 0.0305 0.0522
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0037 0.0099 0.0171
Brugia malayi serine/threonine-protein kinase plk-2 0.0034 0.0084 0.0145
Echinococcus granulosus peptide allatostatin:somatostatin 0.011 0.0505 0.0502
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0121 0.011
Schistosoma mansoni cpg binding protein 0.0079 0.0336 0.0336
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.01 0.045 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Schistosoma mansoni hypothetical protein 0.0745 0.4021 0.4021
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0196 0.0196
Schistosoma mansoni opsin-like receptor 0.011 0.0505 0.0505
Echinococcus multilocularis histone deacetylase 0.0282 0.1458 0.1455
Onchocerca volvulus 0.0073 0.0304 0.052
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0502 0.2673 0.4675
Trypanosoma cruzi histone deacetylase, putative 0.0137 0.0654 0.3727
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0238 0.0238
Toxoplasma gondii hypothetical protein 0.0179 0.0885 0.4523
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0116 0.0541 0.0541
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0025 0.0036 0.0166
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0157 0.0862
Treponema pallidum UDP-N-acetylenolpyruvoylglucosamine reductase 0.174 0.9526 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0254 0.1301 0.1299
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0179 0.0885 0.1546
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.007 0.0286 0.0284
Schistosoma mansoni hypothetical protein 0.0159 0.0775 0.0775
Brugia malayi hypothetical protein 0.0091 0.0401 0.0699
Entamoeba histolytica serine/threonine protein kinase, putative 0.0034 0.0084 0.0462
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0042 0.0027
Plasmodium vivax heat shock protein 90, putative 0.0065 0.0257 0.0773
Trypanosoma brucei cytochrome P450, putative 0.007 0.0286 0.1611
Loa Loa (eye worm) hypothetical protein 0.014 0.0671 0.1174
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0191 0.0955 0.0988
Echinococcus granulosus allatostatin A receptor 0.011 0.0505 0.0502
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0771 0.4399
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0026 0.0041 0.0038
Giardia lamblia NADPH oxidoreductase, putative 0.0085 0.0366 0.214
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0042 0.0027
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.1548
Onchocerca volvulus 0.0179 0.0885 0.1538
Mycobacterium ulcerans lipase LipD 0.0074 0.0305 0.0304
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0025 0.0036 0.0174
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0179 0.0885 0.1546
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0226
Plasmodium vivax glutathione reductase, putative 0.0075 0.0314 0.0952
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi nuclear hormone receptor 0.0037 0.0099 0.0171
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0505 0.0505
Schistosoma mansoni smad1 5 8 and 0.0034 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Echinococcus multilocularis g protein coupled receptor 0.011 0.0505 0.0502
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0129 0.0704
Schistosoma mansoni histamine h1 receptor 0.011 0.0505 0.0505
Onchocerca volvulus 0.011 0.0505 0.0873
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0226 0.1146 0.1146
Echinococcus granulosus solute carrier family 5 0.0026 0.0041 0.0038
Echinococcus multilocularis nAChR subunit 0.0226 0.1146 0.1143
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.01 0.045 0.2637
Brugia malayi jmjC domain containing protein 0.0036 0.0099 0.017
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0034 0.0084 0.0444
Brugia malayi Cytochrome P450 family protein 0.004 0.0121 0.0209
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0505 0.0505
Onchocerca volvulus 0.0054 0.0196 0.0332
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0139 0.0683
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0099 0.0096
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0037 0.0099 0.0096
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0037 0.0099 0.0096
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0226 0.1146 0.1146
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0323 0.1687 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Brugia malayi hypothetical protein 0.0109 0.0502 0.0876
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Schistosoma mansoni 6-phosphofructokinase 0.0073 0.0302 0.0302
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0804 0.4346 0.7603
Schistosoma mansoni nAChR subunit 0.0109 0.0502 0.0502
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0037 0.0099 0.0099
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0042 0.0203
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0172 0.0849 0.0876
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0092 0.0487
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0016 0.001
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0025 0.0036 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0016 0.0057
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0109 0.0502 0.0876
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0036 0.0174
Schistosoma mansoni sodium/solute symporter 0.0026 0.0041 0.0041
Loa Loa (eye worm) doublecortin family protein 0.0091 0.0401 0.0701
Giardia lamblia Heat shock protein HSP 90-alpha 0.0084 0.036 0.2105
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0014 0.0046
Brugia malayi hypothetical protein 0.0049 0.0171 0.0296
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0226 0.1146 0.1143
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0121 0.011
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0037 0.0099 0.0171
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0019 0.0016
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0129 0.0728
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0099 0.0099
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0085 0.0082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0359 0.1885 0.3298
Onchocerca volvulus 0.011 0.0505 0.0873
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0055 0.0204 0.1135
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Plasmodium falciparum transporter, putative 0.0179 0.0885 0.4523
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0305 0.1777
Schistosoma mansoni thyroid hormone receptor 0.0037 0.0099 0.0099
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0055 0.0204 0.061
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0083 0.0354 0.0351
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0091 0.0401 0.0701
Brugia malayi hypothetical protein 0.0019 0.0004 0.0004
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0022 0.0018 0.0015
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.003 0.0064 0.0061
Loa Loa (eye worm) intermediate filament protein 0.0043 0.0134 0.0234
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.0109 0.0502 0.0878
Echinococcus granulosus glycine receptor subunit beta 0.0226 0.1146 0.1143
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0121 0.011
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0116 0.0541 0.0944
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0179 0.0885 0.1548
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0032 0.0032
Onchocerca volvulus 0.011 0.0505 0.0873
Echinococcus granulosus histone deacetylase 6 0.0282 0.1458 0.1455
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0121 0.011
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0073 0.0302 0.0285
Echinococcus granulosus neuropeptide receptor A26 0.011 0.0505 0.0502
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0159 0.0775 0.1355
Trypanosoma cruzi Heat shock protein 83, putative 0.0098 0.0438 0.2483
Brugia malayi beta-lactamase family protein 0.0074 0.0305 0.0532
Schistosoma mansoni inositol monophosphatase 0.0042 0.0129 0.0129
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0055 0.0204 0.1015
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0025 0.0036 0.0033
Toxoplasma gondii histone deacetylase HDAC2 0.0323 0.1687 0.865
Schistosoma mansoni amine GPCR 0.011 0.0505 0.0505
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0042 0.0199
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Trypanosoma brucei polo-like protein kinase 0.0034 0.0084 0.0448
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Schistosoma mansoni acetylcholinesterase 0.0022 0.0018 0.0018
Schistosoma mansoni smad1 5 8 and 0.0034 0.0085 0.0085
Echinococcus granulosus g protein coupled receptor 0.011 0.0505 0.0502
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0029 0.0056 0.0053
Loa Loa (eye worm) hypothetical protein 0.0145 0.0701 0.1226
Loa Loa (eye worm) histone deacetylase 3 0.0323 0.1687 0.295
Schistosoma mansoni ran 0.0055 0.0204 0.0204
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.011 0.0505 0.0505
Brugia malayi hypothetical protein 0.0022 0.0018 0.003
Brugia malayi Zinc carboxypeptidase family protein 0.002 0.0007 0.001
Echinococcus granulosus raf serine:threonine protein kinase 0.0142 0.0683 0.0681
Schistosoma mansoni hypothetical protein 0.0343 0.1795 0.1795
Echinococcus multilocularis neuropeptide Y receptor 0.011 0.0505 0.0502
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0037 0.0099 0.0171
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0254 0.1301 0.2276
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.087 0.0898
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0249 0.1443
Echinococcus multilocularis importin subunit beta 1 0.0075 0.0314 0.0311
Echinococcus granulosus nAChR subunit 0.0226 0.1146 0.1143
Echinococcus granulosus cytosolic carboxypeptidase protein 5 0.002 0.0007 0.0004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0028 0.0025
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.01 0.045 0.2637
Brugia malayi histone deacetylase 11 0.0258 0.1324 0.2315
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0207 0.1041 0.5327
Brugia malayi Bromodomain containing protein 0.0031 0.0067 0.0116
Echinococcus multilocularis thyroid hormone receptor alpha 0.0037 0.0099 0.0096
Echinococcus multilocularis carboxylesterase 5A 0.013 0.0614 0.0611
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0121 0.011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0226 0.1146 0.2002
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0037 0.0099 0.0173
Echinococcus multilocularis histone deacetylase 7 0.0282 0.1458 0.1455
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0226 0.1146 0.1143
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0021 0.0011 0.0008
Echinococcus multilocularis dna polymerase eta 0.0029 0.0056 0.0053
Brugia malayi RE15519p 0.011 0.0505 0.0882
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0155
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0116 0.0541 0.0944
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0123 0.0579 0.0592
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0172 0.0849 0.0876
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0044 0.0044
Echinococcus granulosus neuropeptide receptor 0.011 0.0505 0.0502
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0084 0.0462
Schistosoma mansoni alpha glucosidase 0.0035 0.0092 0.0092
Schistosoma mansoni neuropeptide F-like receptor 0.011 0.0505 0.0505
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0121 0.0656
Plasmodium falciparum thioredoxin reductase 0.0075 0.0314 0.1585
Echinococcus granulosus 6 phosphofructokinase 0.0073 0.0302 0.03
Schistosoma mansoni hypothetical protein 0.0049 0.0171 0.0171
Loa Loa (eye worm) raf kinase 0.0141 0.068 0.1189
Brugia malayi intermediate filament protein 0.0043 0.0134 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0305 0.1777
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0366 0.214
Giardia lamblia Nuclear ATP/GTP-binding protein 0.002 0.0007 0.0003
Loa Loa (eye worm) 6-phosphofructokinase 0.0073 0.0302 0.0529
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0139 0.0683
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0121 0.011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0099 0.0173
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0042 0.0037
Schistosoma mansoni histone deacetylase hda2 0.0282 0.1458 0.1458
Mycobacterium ulcerans 6-phosphofructokinase 0.0073 0.0302 0.0301
Leishmania major mitochondrial DNA polymerase beta 0.0334 0.1744 1
Schistosoma mansoni histone deacetylase 1 2 3 0.0137 0.0654 0.0654
Brugia malayi Doublecortin family protein 0.0091 0.0401 0.0699
Mycobacterium ulcerans heat shock protein 90 0.0092 0.0405 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.0129 0.0129
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0042 0.0199
Loa Loa (eye worm) acetylcholinesterase 1 0.013 0.0614 0.1074
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Brugia malayi TAR-binding protein 0.0193 0.0967 0.1689
Brugia malayi hypothetical protein 0.011 0.0505 0.0882
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0157 0.0765 0.0765
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.1744 1
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0042 0.0129 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0037 0.0099 0.0171
Echinococcus multilocularis heat shock protein 90 0.0098 0.0438 0.0435
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0034 0.0084 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0505 0.0502
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0283
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0042 0.0199
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit beta 0.0047 0.0158 0.0149
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0254 0.1301 0.1299
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0139 0.0789
Toxoplasma gondii exonuclease III APE 0.0022 0.0016 0.0049
Echinococcus granulosus expressed protein 0.0035 0.0093 0.009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0191 0.0955 0.0988
Loa Loa (eye worm) zinc carboxypeptidase 0.002 0.0007 0.0012
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0032 0.0076 0.0073
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0123 0.0579 0.0601
Leishmania major hypothetical protein, conserved 0.0074 0.0305 0.1716
Loa Loa (eye worm) heat shock protein 75 0.0065 0.0257 0.0449
Entamoeba histolytica hypothetical protein 0.0049 0.0171 0.0977
Loa Loa (eye worm) ACC-1 protein 0.0226 0.1146 0.2004
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.002 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0152 0.0266
Schistosoma mansoni amine GPCR 0.011 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0092 0.0507
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0037 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Schistosoma mansoni nAChR subunit 0.0109 0.0502 0.0502
Echinococcus multilocularis lamin 0.0043 0.0134 0.0131
Onchocerca volvulus 0.0024 0.0032 0.0043
Schistosoma mansoni neuropeptide receptor 0.011 0.0505 0.0505
Schistosoma mansoni rab6-interacting 0.0091 0.0401 0.0401
Plasmodium falciparum phenylalanine--tRNA ligase 0.0228 0.116 0.5939
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0064
Echinococcus multilocularis sodium and chloride dependent glycine 0.0179 0.0885 0.0882
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.003 0.0064 0.0109
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0226 0.1146 0.2004
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0121 0.011
Leishmania major heat shock protein 83-1 0.0098 0.0438 0.2483
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0037 0.0099 0.0173
Plasmodium falciparum endoplasmin, putative 0.0071 0.029 0.1459
Trypanosoma brucei glucosidase, putative 0.0035 0.0092 0.0491
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0085 0.0082
Echinococcus granulosus histone deacetylase 0.0282 0.1458 0.1455
Onchocerca volvulus 0.011 0.0505 0.0873
Loa Loa (eye worm) CXXC zinc finger family protein 0.0073 0.0304 0.0531
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0172 0.0849 0.0876
Trypanosoma brucei importin beta-1 subunit, putative 0.0075 0.0314 0.1769
Loa Loa (eye worm) hypothetical protein 0.0226 0.1146 0.2004
Echinococcus granulosus lamin 0.0043 0.0134 0.0131
Trichomonas vaginalis modulator of drug activity B, putative 0.0021 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Echinococcus multilocularis heat shock protein 90 0.0084 0.036 0.0357
Loa Loa (eye worm) hypothetical protein 0.011 0.0505 0.0884
Brugia malayi mbt repeat family protein 0.0054 0.0196 0.0341
Plasmodium vivax amine transporter, putative 0.0179 0.0885 0.2716
Echinococcus granulosus ubiquitin specific protease 41 0.0025 0.0036 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0019 0.0019
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0129 0.0126
Plasmodium vivax histone deacetylase 1, putative 0.0323 0.1687 0.5194
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0042 0.0199
Loa Loa (eye worm) hypothetical protein 0.0116 0.0541 0.0946
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.002 0.0007 0.0004
Echinococcus granulosus GTP binding nuclear protein Ran 0.0055 0.0204 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0121 0.011
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0226 0.1146 0.1143
Brugia malayi GH02984p 0.0236 0.1202 0.21
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.011 0.0505 0.0502
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.1744 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0179 0.0885 0.0882
Schistosoma mansoni neuroligin 3 (S09 family) 0.0022 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0037 0.0099 0.0099
Echinococcus granulosus g protein coupled receptor 0.011 0.0505 0.0502
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0029 0.0056 0.0056
Brugia malayi Melatonin receptor type 1A 0.011 0.0505 0.0882
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0207 0.1041 0.1819
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0363 0.0363
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0109 0.0502 0.0876

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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