Detailed information for compound 1747188

Basic information

Technical information
  • TDR Targets ID: 1747188
  • Name: EU-0100860
  • MW: 450.957 | Formula: C26H27ClN2O3
  • H donors: 3 H acceptors: 2 LogP: 4.11 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c3c1O[C@@H]1C43CCN(C(C2)[C@]4(O)Cc2c1[nH]c1c2cccc1)CC1CC1.Cl
  • InChi: 1S/C26H26N2O3.ClH/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14;/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2;1H/t20?,24-,25?,26+;/m0./s1
  • InChiKey: KNJKRQXCFJCQHC-ONIXXLMQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 2 Starlite/ChEMBL No references
Homo sapiens transient receptor potential cation channel, subfamily V, member 1 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Echinococcus multilocularis potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128858 All targets in OG5_128858
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) voltage and ligand gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum Potassium voltage-gated channel subfamily H member 2, putative Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0018 0.0037
Onchocerca volvulus 0.0012 0.0009 0.0046
Brugia malayi AMP-binding enzyme family protein 0.005 0.0139 0.0138
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0065 0.0191 0.0252
Echinococcus granulosus GPCR family 2 0.0032 0.0076 0.0076
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0091 0.0091
Schistosoma mansoni zinc finger protein 0.0011 0.0004 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0148 0.0148
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.0341 0.0449
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0027 0.0059 0.0303
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus granulosus 7tm_1 domain containing protein 0.0102 0.0316 0.0316
Brugia malayi isocitrate dehydrogenase 0.0019 0.0033 0.0032
Onchocerca volvulus 0.0102 0.0316 0.3292
Brugia malayi nuclear hormone receptor 0.0011 0.0004 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0365 0.3759
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0011 0.0011
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0316 0.0316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0094 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0065 0.0191 0.0262
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0009 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0018 0.0009
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0102 0.0316 0.0312
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Brugia malayi Niemann-Pick C1 protein precursor 0.0198 0.0647 0.0646
Schistosoma mansoni hypothetical protein 0.0742 0.2515 0.2515
Onchocerca volvulus 0.0084 0.0256 0.266
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0015 0.0019 0.0023
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0019 0.0019
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0316 0.0316
Plasmodium falciparum diacylglycerol kinase, putative 0.0082 0.025 0.0964
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.0341 0.3553
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0198 0.0649 0.0649
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0065 0.0191 0.0252
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0018 0.0037
Echinococcus multilocularis allatostatin A receptor 0.0102 0.0316 0.0316
Brugia malayi Rhodanese-like domain containing protein 0.0015 0.0021 0.002
Trichomonas vaginalis cdc25b, putative 0.0198 0.0649 0.6776
Entamoeba histolytica disulphide oxidoreductase, putative 0.0015 0.0019 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0065 0.0191 0.0262
Echinococcus multilocularis carbonic anhydrase II 0.292 1 1
Echinococcus granulosus neuropeptide receptor 0.0102 0.0316 0.0316
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0016 0.0023 0.006
Loa Loa (eye worm) cytochrome P450 0.0065 0.0191 0.0187
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0065 0.0191 0.0182
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0019 0.0196
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0102 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0017
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0059 0.0069
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0019 0.0019
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0038 0.0097 0.0131
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.0046
Loa Loa (eye worm) hypothetical protein 0.0044 0.012 0.0116
Echinococcus granulosus ceramide kinase 0.0082 0.025 0.025
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0033 0.0033
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0102 0.0138
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0203 0.0202
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0382 0.0377
Brugia malayi conserved hypotetical protein 0.0011 0.0004 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0242 0.0932
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0054 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0092
Trypanosoma brucei PAB1-binding protein , putative 0.008 0.0242 0.0233
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0316 0.0316
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0198 0.0649 0.6776
Brugia malayi AMP-binding enzyme family protein 0.005 0.0139 0.0138
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0018 0.0037
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0011 0.0011
Toxoplasma gondii hypothetical protein 0.0742 0.2515 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0241 0.0795 0.0792
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0412 0.1384 0.1913
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0046 0.0046
Schistosoma mansoni ap endonuclease 0.0019 0.0033 0.0033
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0004
Trichomonas vaginalis bmru protein, putative 0.0082 0.025 0.2539
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.0015 0.0018 0.0014
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0161 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Echinococcus multilocularis carbonic anhydrase 0.0742 0.2515 0.2515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0116 0.1111
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0739 0.2508 0.3468
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0102 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0065 0.0191 0.0262
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0054 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0065 0.0191 0.0262
Schistosoma mansoni survival motor neuron protein 0.0049 0.0135 0.0135
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0017 0.0027 0.0024
Mycobacterium ulcerans polyketide synthase 0.0027 0.0059 0.0069
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0065 0.0191 0.0252
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0102 0.0316 0.0315
Mycobacterium ulcerans glutamate synthase subunit beta 0.0015 0.0019 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0259 0.0259
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.0015 0.0021 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0163 0.0526 1
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0316 0.0312
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0046 0.0046
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0018 0.0012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0046 0.0046
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0116 0.0365 0.0502
Toxoplasma gondii rhodanese family domain-containing protein 0.0015 0.0021 0.0048
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0033 0.047
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.0015 0.0021 0.0343
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0046 0.0046
Leishmania major hypothetical protein, conserved 0.0082 0.025 0.0241
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0019 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0046 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0018 0.0012
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0019 0.001
Echinococcus granulosus cytochrome P450 2K1 0.0065 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0027 0.006 0.0056
Schistosoma mansoni adenoreceptor 0.0102 0.0316 0.0316
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0015 0.0019 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0102 0.0316 0.0316
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0139 0.013
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0199 0.0759
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable lipase LipD 0.0116 0.0365 0.0502
Brugia malayi diacylglycerol kinase 0.0082 0.025 0.0249
Schistosoma mansoni amine GPCR 0.0102 0.0316 0.0316
Plasmodium vivax ataxin-2 like protein, putative 0.008 0.0242 0.4514
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0015 0.0019 0.0019
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0161 0.0152
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0076
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.292 1 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0017 0.0025 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0316 0.0316
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0242 0.0238
Leishmania major cytochrome p450-like protein 0.0106 0.033 0.0321
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0019 0.0007
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0065 0.0191 0.0252
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.0015 0.0021 0.0025
Schistosoma mansoni hypothetical protein 0.0065 0.0191 0.0191
Echinococcus granulosus expressed conserved protein 0.0186 0.0606 0.0606
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Echinococcus granulosus orexin receptor type 2 0.0102 0.0316 0.0316
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.025 0.0241
Onchocerca volvulus 0.0082 0.025 0.2593
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0102 0.0129
Echinococcus granulosus carbonic anhydrase 0.0742 0.2515 0.2515
Echinococcus granulosus lamin dm0 0.0058 0.0168 0.0168
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0046 0.0046
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0048 0.0131 0.013
Brugia malayi MH2 domain containing protein 0.0121 0.0382 0.0381
Echinococcus multilocularis cpg binding protein 0.0035 0.0087 0.0087
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Leishmania major diacylglycerol kinase, putative 0.0082 0.025 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0049 0.004
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0099 0.0098
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0082 0.025 0.025
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0039 0.0051
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0004 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0033 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0365 0.0356
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0082 0.025 0.0964
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0046 0.0046
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0046 0.0046
Mycobacterium tuberculosis Probable esterase LipL 0.0116 0.0365 0.0502
Mycobacterium leprae Polyketide synthase Pks13 0.0038 0.0097 0.0577
Schistosoma mansoni amine GPCR 0.0102 0.0316 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0259 0.2635
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.006 0.0051
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0102 0.0316 0.0312
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0102 0.0316 0.0316
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0018 0.0014
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0161 0.0608
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.0316 0.0316
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0316 0.0316
Trypanosoma brucei polo-like protein kinase 0.0109 0.0341 0.0332
Trypanosoma brucei NADH dehydrogenase 0.0015 0.0019 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0094 0.0339
Onchocerca volvulus 0.0102 0.0316 0.3292
Schistosoma mansoni sphingoid long chain base kinase 0.2113 0.7228 0.7228
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.011 0.0109
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0102 0.0316 0.0316
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0033 0.0033
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0011 0.0011
Toxoplasma gondii type I fatty acid synthase, putative 0.0029 0.0066 0.023
Leishmania major cytochrome p450-like protein 0.0065 0.0191 0.0182
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0049 0.2103
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0004 0.0004
Echinococcus granulosus Diacylglycerol kinase theta 0.0082 0.025 0.025
Onchocerca volvulus 0.0058 0.0168 0.1723
Schistosoma mansoni hypothetical protein 0.0082 0.0249 0.0249
Schistosoma mansoni amine GPCR 0.0102 0.0316 0.0316
Leishmania major DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Giardia lamblia Thioredoxin reductase 0.0015 0.0019 0.0288
Echinococcus granulosus tm gpcr rhodopsin 0.0727 0.2464 0.2464
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0046 0.0045
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0046 0.0046
Echinococcus multilocularis musashi 0.0058 0.0168 0.0168
Echinococcus granulosus neuropeptide receptor A26 0.0657 0.2225 0.2225
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0163 0.0526 0.0725
Mycobacterium ulcerans polyketide synthase Pks9 0.0017 0.0025 0.0021
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0019 0.0082
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0038 0.0097 0.0131
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0019 0.0013
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0033 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0046 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0046 0.0041
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0046 0.0436
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0102 0.0316 0.0316
Echinococcus granulosus 7TM GPCR rhodopsin 0.0102 0.0316 0.0316
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0198 0.0647 0.0873
Leishmania major cytochrome p450-like protein 0.0065 0.0191 0.0182
Loa Loa (eye worm) hypothetical protein 0.0084 0.0256 0.0252
Onchocerca volvulus 0.0102 0.0316 0.3292
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0049 0.0774
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0316 0.0316
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0025 0.0054 0.0264
Brugia malayi neuropeptide F receptor 0.0102 0.0316 0.0315
Mycobacterium ulcerans thioesterase 0.0021 0.0039 0.0042
Echinococcus granulosus neuropeptide s receptor 0.0657 0.2225 0.2225
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0065 0.0191 0.0262
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0004 0.0004
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0015 0.0021 0.0101
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0371 0.1242 0.1716
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0015 0.0019 0.0013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0087 0.0087
Echinococcus multilocularis GPCR, family 2 0.0032 0.0076 0.0076
Onchocerca volvulus 0.0102 0.0316 0.3292
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0316 0.0312
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0161 0.022
Schistosoma mansoni opsin-like receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0033 0.0024
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0048 0.0134 0.013
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.0341 0.0332
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0019 0.0082
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0054 0.0062
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0139 0.018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Onchocerca volvulus 0.0102 0.0316 0.3292
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0065 0.0191 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Onchocerca volvulus 0.0116 0.0365 0.3804
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0015 0.0019 0.0023
Brugia malayi Diacylglycerol kinase protein 2 0.0082 0.025 0.0249
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.0381 0.0381
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Loa Loa (eye worm) hypothetical protein 0.0153 0.0492 0.0488
Loa Loa (eye worm) hypothetical protein 0.2113 0.7228 0.7226
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Brugia malayi glutathione reductase 0.0163 0.0526 0.0525
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0065 0.0191 0.0252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0025 0.0025
Echinococcus multilocularis Niemann Pick C1 protein 0.0198 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0135
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0046 0.0046
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0259 0.0259
Onchocerca volvulus 0.0015 0.0019 0.0153
Loa Loa (eye worm) hypothetical protein 0.0742 0.2515 0.2512
Loa Loa (eye worm) hypothetical protein 0.0307 0.1021 0.1017
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.2831 0.2831
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0116 0.0365 0.0361
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0089 0.012
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0004 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0046 0.0046
Plasmodium falciparum ferrodoxin reductase-like protein 0.0015 0.0019 0.0041
Brugia malayi hypothetical protein 0.0011 0.0004 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0316 0.0316
Brugia malayi G protein-coupled receptor 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0102
Onchocerca volvulus 0.0198 0.0649 0.6799
Leishmania major hypothetical protein, conserved 0.008 0.0242 0.0233
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0312 0.0311
Echinococcus multilocularis geminin 0.0362 0.1212 0.1212
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0198 0.0649 0.6776
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Brugia malayi putative neuropeptide receptor NPR1 0.0102 0.0316 0.0315
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0019 0.0018
Echinococcus granulosus geminin 0.0362 0.1212 0.1212
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0065 0.0191 0.0252
Onchocerca volvulus 0.0102 0.0316 0.3292
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0049 0.2103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.0381 0.0372
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0076 0.0075
Brugia malayi Pre-SET motif family protein 0.0037 0.0094 0.0093
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Echinococcus multilocularis sex peptide receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0025 0.0054 0.0071
Mycobacterium ulcerans hypothetical protein 0.005 0.0139 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0092
Entamoeba histolytica rodhanase-like domain containing protein 0.0015 0.0021 0.0004
Leishmania major DNA polymerase eta, putative 0.0039 0.0102 0.0093
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.011 0.1054
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.0015 0.0021 0.0016
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0019 0.001
Schistosoma mansoni amine GPCR 0.0102 0.0316 0.0316
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0096 0.5416
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0007 0.0007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0033 0.0033
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0027 0.0059 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0015 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0365 0.0356
Trypanosoma cruzi cytochrome P450, putative 0.0106 0.033 0.0321
Echinococcus granulosus sphingosine kinase 1 0.2113 0.7228 0.7228
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0033 0.0081 0.0805
Echinococcus multilocularis heat shock protein 67b2 0.0015 0.0021 0.0021
Brugia malayi CXXC zinc finger family protein 0.0033 0.0081 0.008
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.0015 0.0021 0.0011
Onchocerca volvulus 0.0058 0.0168 0.1723
Leishmania major hypothetical protein, conserved 0.0015 0.0019 0.001
Schistosoma mansoni hypothetical protein 0.0015 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0082 0.025 0.0964
Brugia malayi Cyclic-nucleotide gated cation channel 0.0013 0.0011 0.001
Giardia lamblia Kinase, PLK 0.0109 0.0341 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0164 0.0531 0.0531
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0017 0.0027 0.0026
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Entamoeba histolytica rodhanase-like domain containing protein 0.0198 0.0649 0.0875
Onchocerca volvulus Fatty acid synthase homolog 0.0045 0.0123 0.1256
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus granulosus carbonic anhydrase 0.0742 0.2515 0.2515
Echinococcus granulosus alpha 1A adrenergic receptor 0.0102 0.0316 0.0316
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0046 0.0046
Echinococcus granulosus muscleblind protein 0.0307 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.0198 0.0647 0.0643
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0259 0.0259
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0116 0.0365 0.0364
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0102 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0362 0.1212 0.1212
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0161 0.021
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.292 1 1
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0015 0.0019 0.0007
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0046 0.0046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.0316 0.0316
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0004 0.0003
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0046 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0101
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Schistosoma mansoni carbonic anhydrase-related 0.0742 0.2515 0.2515
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0021 0.002
Brugia malayi tailless protein 0.0011 0.0004 0.0003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0102 0.0968
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0015 0.0019 0.0023
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0019 0.001
Brugia malayi beta-lactamase family protein 0.0116 0.0365 0.0364
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.0015 0.0021 0.0025
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0161 0.1593
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0742 0.2515 0.2514
Brugia malayi nuclear receptor NHR-88 0.0011 0.0004 0.0003
Brugia malayi Patched related family protein 10 0.0012 0.0009 0.0008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0458 0.0458
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0046 0.0045
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0102 0.0316 0.0316
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0094 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Brugia malayi CHE-14 protein 0.0085 0.0259 0.0258
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0116 0.2069
Schistosoma mansoni hypothetical protein 0.0362 0.1212 0.1212
Loa Loa (eye worm) hypothetical protein 0.0082 0.025 0.0246
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0161 0.0152
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0168 0.0163
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0139 0.018
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0033 0.0032
Onchocerca volvulus 0.0012 0.0009 0.0046
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Echinococcus granulosus Niemann Pick C1 protein 0.0198 0.0647 0.0647
Echinococcus granulosus somatostatin receptor 0.0102 0.0316 0.0316
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.0015 0.0021 0.0021
Echinococcus multilocularis serotonin receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0161 0.0152
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0076 0.0072
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0102 0.0316 0.0315
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0065 0.0191 0.0182
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0065 0.0191 0.0262
Schistosoma mansoni biogenic amine receptor 0.0102 0.0316 0.0316
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.0009
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0082 0.025 0.2539
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0381 0.0381
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0056 0.0161 1
Schistosoma mansoni glutamate synthase 0.0015 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Entamoeba histolytica rodhanase-like domain containing protein 0.0015 0.0021 0.0004
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0161 0.2945
Brugia malayi RIKEN cDNA 4930451A13 0.0015 0.0021 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0082 0.025 0.0241
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0065 0.0191 0.0252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0594 0.0594
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0082 0.025 0.0246
Loa Loa (eye worm) cytochrome P450 family protein 0.0106 0.033 0.0326
Loa Loa (eye worm) hypothetical protein 0.0183 0.0596 0.0592
Toxoplasma gondii selenide, water dikinase 0.0015 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi Thioredoxin reductase 0.0163 0.0526 0.0525
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0019
Brugia malayi Cytochrome P450 family protein 0.0065 0.0191 0.019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Schistosoma mansoni opsin-like receptor 0.0102 0.0316 0.0316
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0018 0.0018
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.0788 0.0788
Schistosoma mansoni neuropeptide receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans hypothetical protein 0.0015 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.0114 0.0109
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Mycobacterium ulcerans diacylglycerol kinase 0.0082 0.025 0.0334
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0025 0.0054 0.0053
Mycobacterium leprae Probable lipase LipE 0.0116 0.0365 0.2541
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0049 0.016
Onchocerca volvulus 0.0102 0.0316 0.3292
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0019 0.0082
Schistosoma mansoni hypothetical protein 0.0102 0.0316 0.0316
Leishmania major hypothetical protein, conserved 0.0116 0.0365 0.0356
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0021 0.0038 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0102 0.0316 0.0315
Toxoplasma gondii LsmAD domain-containing protein 0.008 0.0242 0.0932
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0076 0.0076
Brugia malayi MoeZ/MoeB domain containing protein 0.0015 0.0021 0.002
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0011 0.0011
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0065 0.0191 0.0262
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0049 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0594 0.0594
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0381 0.0381
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor 0.0102 0.0316 0.0316
Echinococcus multilocularis muscleblind protein 1 0.0307 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0018 0.0018
Echinococcus multilocularis carbonic anhydrase 0.0742 0.2515 0.2515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0046 0.0041
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0049 0.0064
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0014
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0018 0.0009
Schistosoma mansoni patched 1 0.0085 0.0259 0.0259
Plasmodium vivax rhodanese like protein, putative 0.0015 0.0021 0.0232
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0102 0.0102
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0135 0.0134
Schistosoma mansoni hypothetical protein 0.0015 0.0021 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.01 0.0312 0.0308
Plasmodium falciparum rhodanese like protein, putative 0.0015 0.0021 0.0048
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0033 0.0032
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0371 0.1242 0.1716
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0381 0.0514
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0038 0.0099 0.0095
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0102 0.0102
Trichomonas vaginalis sphingosine kinase, putative 0.0082 0.025 0.2539
Brugia malayi Dopamine receptor protein 2 0.0102 0.0316 0.0315
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0015 0.0019 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0139 0.018
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0017 0.0027 0.0024
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0065 0.0191 0.0252
Echinococcus multilocularis g-protein coupled receptor 0.0102 0.0316 0.0316
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0033 0.0973
Brugia malayi AMP-binding enzyme family protein 0.005 0.0139 0.0138
Schistosoma mansoni ap endonuclease 0.0019 0.0033 0.0033
Onchocerca volvulus 0.0015 0.0018 0.0143
Brugia malayi hypothetical protein 0.0052 0.0145 0.0144
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0015 0.0019 0.0019
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0015 0.0019 0.0013
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Onchocerca volvulus 0.0012 0.0009 0.0046
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0058 0.0168 0.0163
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0101
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0102 0.0968
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0594 0.059
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0082 0.025 0.0241
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0033 0.0229
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0019 0.0018
Echinococcus granulosus g protein coupled receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0007 0.0003
Onchocerca volvulus 0.0102 0.0316 0.3292
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0082 0.025 0.2539
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0015 0.0019 0.0013
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.025 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0152 0.1501
Mycobacterium tuberculosis Probable reductase 0.0371 0.1242 0.1716
Schistosoma mansoni hypothetical protein 0.0069 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0469 0.158 0.158
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0594 0.0593
Mycobacterium tuberculosis Diacylglycerol kinase 0.0082 0.025 0.0343
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0239 0.0788 0.0784
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0102 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.006 0.0051
Echinococcus multilocularis lamin dm0 0.0058 0.0168 0.0168
Brugia malayi polk-prov protein 0.0012 0.0009 0.0008
Brugia malayi sulfakinin receptor protein 0.0102 0.0316 0.0315
Brugia malayi Patched related family protein 4 0.0012 0.0009 0.0008
Giardia lamblia Glutamate synthase 0.0015 0.0019 0.0288
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0033 0.0033
Brugia malayi GnHR receptor homolog 0.0102 0.0316 0.0315
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0065 0.0191 0.0252
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0256 0.0256
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0102 0.0102
Echinococcus granulosus tachykinin peptides receptor 99D 0.0102 0.0316 0.0316
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0015 0.0019 0.001
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Loa Loa (eye worm) programmed cell death 8 0.0015 0.0019 0.0015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0161 0.0608
Onchocerca volvulus 0.0102 0.0316 0.3292
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0103 0.2835
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0046 0.0046
Schistosoma mansoni disulfide oxidoreductase 0.0015 0.0019 0.0019
Echinococcus granulosus Diacylglycerol kinase zeta 0.0082 0.025 0.025
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0019 0.001
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0065 0.0191 0.0262
Giardia lamblia DINP protein human, muc B family 0.0039 0.0102 0.28
Brugia malayi nuclear receptor NHR-67 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0076
Onchocerca volvulus Huntingtin homolog 0.0124 0.0393 0.4103
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0161 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0596 0.0592
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0076 0.0076
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0139 0.018
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0011 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0076 0.0076
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0046 0.0046
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0019 0.001
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.0788 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0341 0.0341
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0102 0.0316 0.0316
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0139 0.0889
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0201 0.0658 0.0658
Schistosoma mansoni hypothetical protein 0.0082 0.0249 0.0249
Leishmania major trypanothione reductase 0.0163 0.0526 0.0517
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0004
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0015 0.0019 0.0041
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.006 0.0051
Echinococcus multilocularis sphingosine kinase 1 0.2113 0.7228 0.7228
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.0341 0.034
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0082 0.025 0.025
Onchocerca volvulus Ceramide kinase 1 homolog 0.0082 0.025 0.2593
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0312 0.0308
Onchocerca volvulus 0.0153 0.0492 0.5139
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0116 0.0365 0.0502
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0065 0.0191 0.0262
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.0015 0.0021 0.002
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0015 0.0021 0.0025
Leishmania major carbonic anhydrase-like protein 0.292 1 1
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0015 0.0021 0.0101
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.025 0.0322
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0046 0.0046
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0033 0.0097
Schistosoma mansoni neuropeptide receptor 0.0102 0.0316 0.0316
Brugia malayi Cytochrome P450 family protein 0.0106 0.033 0.0329
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0046 0.0045
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0018 0.0038
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0004
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0102 0.0316 0.0316
Schistosoma mansoni neuropeptide f receptor 76f 0.0102 0.0316 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0092
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0161 0.0608
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0139 0.0889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0038 0.0099 0.0133
Echinococcus multilocularis G-protein coupled receptor, putative 0.0102 0.0316 0.0316
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0472 0.0472
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0065 0.0191 0.0252
Loa Loa (eye worm) hypothetical protein 0.0082 0.025 0.0246
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0365 0.3759
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.0365 0.3759
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0033 0.0229
Brugia malayi beta-lactamase family protein 0.0116 0.0365 0.0364
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0139 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.025 0.0322
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0365 0.6887
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0152 0.1501
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0046 0.0436
Loa Loa (eye worm) hypothetical protein 0.0124 0.0393 0.0389
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0033 0.0033
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0011 0.0007
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0011 0.0011
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.0163 0.0526 0.0517
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0065 0.0191 0.0252
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.292 1 1
Onchocerca volvulus 0.0012 0.0009 0.0046
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0161 0.0152
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0094 0.0094
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0212 0.0212
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.0009
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0065 0.0191 0.0252
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0046 0.0046
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0015 0.0019 0.0001
Schistosoma mansoni cpg binding protein 0.0035 0.0087 0.0087
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Schistosoma mansoni biogenic amine receptor 0.0102 0.0316 0.0316
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0015 0.0021 0.0021
Echinococcus granulosus dna polymerase kappa 0.0039 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Brugia malayi Rhodanese-like domain containing protein 0.0198 0.0649 0.0648
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Leishmania major sphingosine kinase A, B, putative 0.0082 0.025 0.0241
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0021
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0065 0.0191 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0102 0.0093
Entamoeba histolytica hypothetical protein 0.0015 0.0021 0.0004
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0082 0.025 0.2539
Brugia malayi intermediate filament protein 0.0058 0.0168 0.0167
Mycobacterium tuberculosis Probable dehydrogenase 0.0371 0.1242 0.1716
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0102 0.0316 0.0316
Schistosoma mansoni growth hormone secretagogue receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0065 0.0191 0.0262
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0018 0.0072
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0102 0.0098
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0015 0.0019 0.0001
Echinococcus granulosus Rhodanese 0.0015 0.0021 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0033 0.0023
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0065 0.0191 0.0252
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Plasmodium falciparum thioredoxin reductase 0.0163 0.0526 0.2065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0148 0.0181
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0069 0.0203 0.0199
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0027 0.0059 0.0079
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0015 0.0019 0.0196
Trichomonas vaginalis bmru protein, putative 0.0082 0.025 0.2539
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0046 0.0045
Schistosoma mansoni hypothetical protein 0.0082 0.025 0.025
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0139 0.0168
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0033 0.0464
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0017 0.0027 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.0657 0.2225 0.2225
Schistosoma mansoni hypothetical protein 0.0102 0.0316 0.0316
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0046 0.0046
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0161 0.0152
Trichomonas vaginalis diacylglycerol kinase, putative 0.0082 0.025 0.2539
Onchocerca volvulus 0.0102 0.0316 0.3292
Mycobacterium leprae conserved hypothetical protein 0.0116 0.0365 0.2541
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0033 0.0023
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0065 0.0191 0.0182
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0065 0.0191 0.0182
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma brucei diacylglycerol kinase, putative 0.0082 0.025 0.0241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0094 0.0089
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0009 0.0002
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0019 0.001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0102 0.0316 0.0312
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0102 0.0316 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0046 0.0045
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.0341 0.0341
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0198 0.0649 0.0645
Mycobacterium ulcerans ferredoxin reductase 0.0015 0.0019 0.0013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0011 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0046 0.0045
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0742 0.2515 0.2514
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0004 0.0003
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Giardia lamblia Hypothetical protein 0.0015 0.0021 0.0343
Loa Loa (eye worm) hypothetical protein 0.0742 0.2515 0.2512
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.0015 0.0021 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0046 0.0045
Brugia malayi Patched protein homolog 1 0.0012 0.0009 0.0008
Echinococcus multilocularis protein patched 0.0085 0.0259 0.0259
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0139 0.018
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0124 0.0393 0.0389
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0198 0.0649 0.0649
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0033 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0116 0.0365 0.0502
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0168 0.0163
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0102 0.0316 0.0316
Echinococcus granulosus beta LACTamase domain containing family member 0.0116 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus granulosus allatostatin A receptor 0.0102 0.0316 0.0316
Echinococcus multilocularis centrosomal protein of 41 kDa 0.0015 0.0021 0.0021
Echinococcus granulosus peptide allatostatin:somatostatin 0.0102 0.0316 0.0316
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0018 0.0009
Leishmania major hypothetical protein, conserved 0.0082 0.025 0.0241
Schistosoma mansoni diacylglycerol kinase theta 0.0082 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus multilocularis protein dispatched 1 0.0097 0.03 0.03
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0017 0.0027 0.0034
Brugia malayi Eye-specific diacylglycerol kinase 0.0082 0.025 0.0249
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0076 0.0075
Echinococcus granulosus G protein coupled receptor 139 0.0102 0.0316 0.0316
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0094 0.0094
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0065 0.0191 0.0262
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0033 0.0029
Entamoeba histolytica hypothetical protein 0.0015 0.0021 0.0004
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0015 0.0019 0.0023
Onchocerca volvulus 0.0049 0.0135 0.1375
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0033 0.0032
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0013 0.0011 0.0012
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Plasmodium vivax diacylglycerol kinase, putative 0.0082 0.025 0.4667
Echinococcus granulosus centrosomal protein of 41 kDa 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0102 0.0316 0.3292
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0365 0.0365
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0316 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0033 0.0705
Brugia malayi Rhodanese-like domain containing protein 0.0015 0.0021 0.002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0046 0.0046
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0064 0.0064
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0015 0.0019 0.0082
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0017 0.0027 0.0034
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0161 1
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0009 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Brugia malayi Muscleblind-like protein 0.0307 0.1021 0.102
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0059 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0161 0.0161
Leishmania major hypothetical protein, conserved 0.0015 0.0019 0.001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0018 0.0178
Schistosoma mansoni kinase 0.0055 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.006 0.0056
Loa Loa (eye worm) hypothetical protein 0.0104 0.0325 0.0321
Onchocerca volvulus 0.0017 0.0027 0.0235
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0018 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0046 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0065 0.0191 0.0262
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0015 0.0019 0.0015
Schistosoma mansoni histamine h1 receptor 0.0102 0.0316 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Chlamydia trachomatis hypothetical protein 0.0015 0.0021 0.0129
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Brugia malayi Dopamine receptor protein 1 0.0102 0.0316 0.0315
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0018 0.0017
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0009 0.0009
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0033 0.0097
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0096 0.1685
Schistosoma mansoni dual specificity protein phosphatase 0.0015 0.0021 0.0021
Loa Loa (eye worm) ceramide kinase 0.0082 0.025 0.0246
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0135
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.0015 0.0021 0.002
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0102 0.0316 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0027 0.0024
Onchocerca volvulus 0.0116 0.0365 0.3804
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0046 0.0046
Toxoplasma gondii ABC1 family protein 0.0116 0.0365 0.1422
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0064 0.006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0081 0.0076
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0025 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Onchocerca volvulus 0.0102 0.0316 0.3292
Brugia malayi glutamate synthase 0.0015 0.0019 0.0018
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0004
Echinococcus multilocularis expressed conserved protein 0.0186 0.0606 0.0606
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.2831 0.2831
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Loa Loa (eye worm) hypothetical protein 0.0032 0.0076 0.0072
Brugia malayi Putative carbonic anhydrase 5 precursor 0.292 1 1
Onchocerca volvulus 0.0015 0.0021 0.0172
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0046 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0082 0.025 0.0241
Giardia lamblia Hypothetical protein 0.0015 0.0021 0.0343
Echinococcus granulosus thioredoxin glutathione reductase 0.0164 0.0531 0.0531
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0017 0.0027 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0046 0.0045
Trypanosoma brucei unspecified product 0.0027 0.006 0.0051
Brugia malayi Serotonin receptor 0.0102 0.0316 0.0315
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0412 0.1384 0.1913
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0004 0.0004
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Loa Loa (eye worm) melatonin receptor type 1A 0.0102 0.0316 0.0312
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0472 0.0471
Onchocerca volvulus 0.0023 0.0046 0.0436
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0009 0.0004
Brugia malayi Cytochrome P450 family protein 0.0106 0.033 0.0329
Brugia malayi hypothetical protein 0.0124 0.0393 0.0392
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0011 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0025 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0094 0.0094
Brugia malayi nuclear receptor RXR 0.0011 0.0004 0.0003
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0018 0.0009
Echinococcus multilocularis neuropeptide FF receptor 2 0.0102 0.0316 0.0316
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma brucei Sphingosine kinase 0.0082 0.025 0.0241
Echinococcus granulosus intermediate filament protein 0.0058 0.0168 0.0168
Mycobacterium ulcerans lipase LipD 0.0116 0.0365 0.0493
Trypanosoma brucei carbonic anhydrase-like protein 0.292 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0139 0.0168
Schistosoma mansoni hypothetical protein 0.0102 0.0316 0.0316
Mycobacterium ulcerans polyketide synthase 0.0025 0.0054 0.0062
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.2113 0.7228 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0102 0.0316 0.3292
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0101
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0049 0.0055
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0065 0.0191 0.0252
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0004 0.0004
Onchocerca volvulus 0.005 0.0139 0.1424
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0065 0.0191 0.0252
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.0015 0.0021 0.0048
Trichomonas vaginalis cdc25c, putative 0.0015 0.0021 0.0101
Brugia malayi Dopamine receptor 0.0102 0.0316 0.0315
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0102 0.0316 0.0312
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0004 0.0004
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0021 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0046 0.0045
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0009 0.0008
Trypanosoma brucei cytochrome P450, putative 0.0106 0.033 0.0321
Echinococcus granulosus microtubule associated protein 2 0.0833 0.2831 0.2831
Brugia malayi beta-lactamase 0.0116 0.0365 0.0364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0015 0.0019 0.0013
Leishmania major NADH dehydrogenase, putative 0.0015 0.0019 0.001
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0017 0.0027 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0102 0.0138
Onchocerca volvulus 0.0198 0.0649 0.6799
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0049 0.016
Loa Loa (eye worm) diacylglycerol kinase 2 0.0082 0.025 0.0246
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0082 0.025 0.025
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0019 0.0019
Schistosoma mansoni myosin xvIII 0.0102 0.0316 0.0316
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0256 0.0256
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0096 0.0129
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0019 0.001
Echinococcus multilocularis dna polymerase eta 0.0039 0.0102 0.0102
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0015 0.0019 0.001
Schistosoma mansoni cpg binding protein 0.0033 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Echinococcus granulosus heat shock protein 67b2 0.0015 0.0021 0.0021
Echinococcus multilocularis dro:myosuppressin receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans NADH dehydrogenase 0.0015 0.0019 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0139 0.018
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0015 0.0019 0.0007
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0021 0.0011
Echinococcus multilocularis G protein coupled receptor 139 0.0102 0.0316 0.0316
Schistosoma mansoni nuclear receptor 0.0011 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0102 0.0316 0.0316
Schistosoma mansoni cpg binding protein 0.0035 0.0087 0.0087
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0018 0.0018
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.0015 0.0021 0.0101
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0259 0.0255
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0742 0.2515 0.2514
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0065 0.0191 0.0252
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Brugia malayi follicle stimulating hormone receptor 0.0102 0.0316 0.0315
Brugia malayi RE15519p 0.0102 0.0316 0.0315
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.0365 0.0365
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0091 0.0091
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0033 0.0042
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0011 0.0011
Schistosoma mansoni lamin 0.0058 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma cruzi Sphingosine kinase 0.0082 0.025 0.0241
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Echinococcus granulosus carbonic anhydrase 0.0742 0.2515 0.2515
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0015 0.0019 0.0041
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0116 0.1111
Echinococcus multilocularis g protein coupled receptor 0.0102 0.0316 0.0316
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0161 0.0152
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.011 0.0109
Echinococcus granulosus cpg binding protein 0.0035 0.0087 0.0087
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0048 0.0134 0.0134
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Echinococcus multilocularis muscleblind protein 0.0307 0.1021 0.1021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0046 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.0106 0.033 0.0326
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0006 0.0005
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0015 0.0019 0.0007
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0076
Brugia malayi Patched related family protein 12 0.0012 0.0009 0.0008
Schistosoma mansoni coup transcription factor 0.0023 0.0046 0.0046
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0103 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0019 0.001
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0048 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.0015 0.0021 0.002
Echinococcus multilocularis fmrfamide receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0089 0.012
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0015 0.0021 0.0101
Plasmodium falciparum glutathione reductase 0.0163 0.0526 0.2065
Trypanosoma brucei trypanothione reductase 0.0163 0.0526 0.0517
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0015 0.0019 0.0018
Echinococcus multilocularis ceramide kinase 0.0082 0.025 0.025
Mycobacterium tuberculosis Conserved protein 0.2113 0.7228 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0075 0.007
Entamoeba histolytica hypothetical protein 0.0015 0.0021 0.0004
Entamoeba histolytica rodhanase-like domain containing protein 0.0198 0.0649 0.0875
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0018 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0242 0.0932
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0015 0.0019 0.001
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0046 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Trichomonas vaginalis esterase, putative 0.0116 0.0365 0.3759
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0065 0.0191 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0065 0.0191 0.0262
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0054 0.0062
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.0015 0.0021 0.0025
Schistosoma mansoni hypothetical protein 0.0082 0.0249 0.0249
Schistosoma mansoni 60S ribosomal protein L21 0.0011 0.0005 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0161 0.0161
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0161 0.021
Onchocerca volvulus Neuropeptide F receptor homolog 0.0102 0.0316 0.3292
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0011 0.0011
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0065 0.0191 0.0252
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0135
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0019 0.0001
Schistosoma mansoni hypothetical protein 0.0102 0.0316 0.0316
Echinococcus granulosus dro:myosuppressin receptor 0.0102 0.0316 0.0316
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Brugia malayi nuclear receptor RXR 0.0012 0.0009 0.0008
Brugia malayi Serotonin receptor 0.0102 0.0316 0.0315
Echinococcus granulosus carbonic anhydrase II 0.292 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0065 0.0191 0.0262
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0312 0.0311
Plasmodium falciparum diacylglycerol kinase, putative 0.0082 0.025 0.0964
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.0046
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.0015 0.0021 0.0016
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0381 0.0514
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0161 0.2945
Onchocerca volvulus Huntingtin homolog 0.0124 0.0393 0.4103
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0096 0.0348
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0037 0.014
Schistosoma mansoni hypothetical protein 0.0015 0.0021 0.0021
Brugia malayi steroid hormone receptor 0.0023 0.0046 0.0045
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0051 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0015 0.0019 0.0019
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0742 0.2515 0.2514
Trichomonas vaginalis cdc25c, putative 0.0198 0.0649 0.6776
Onchocerca volvulus 0.0059 0.0168 0.1732
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0161 0.4572
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0021
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0076 0.0076
Loa Loa (eye worm) acetyltransferase 0.0147 0.0472 0.0468
Brugia malayi nuclear hormone receptor 0.0023 0.0046 0.0045
Schistosoma mansoni glutamate synthase 0.0015 0.0019 0.0019
Echinococcus granulosus hypothetical protein 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0014
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0017 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.0015 0.0021 0.0025
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0027 0.0059 0.0079
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0103 0.0378
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.0341 0.0332
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0011 0.0011
Mycobacterium ulcerans monoxygenase 0.0015 0.0019 0.0013
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0015 0.0019 0.0019
Echinococcus granulosus glutamate synthase 0.0015 0.0019 0.0019
Giardia lamblia Thiosulfate sulfurtransferase 0.0015 0.0021 0.0343
Schistosoma mansoni glutamate synthase 0.0015 0.0019 0.0019
Brugia malayi G-protein coupled receptor 0.0102 0.0316 0.0315
Entamoeba histolytica hypothetical protein 0.0024 0.0049 0.0043
Loa Loa (eye worm) hypothetical protein 0.0307 0.1021 0.1017
Treponema pallidum NADH oxidase 0.0056 0.0161 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0316 0.0316
Schistosoma mansoni intermediate filament proteins 0.0058 0.0168 0.0168
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0015 0.0019 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0102 0.0316 0.0316
Echinococcus granulosus neuropeptide FF receptor 2 0.0102 0.0316 0.0316
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0033 0.0024
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0102 0.0316 0.0316
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0594 0.0594
Mycobacterium tuberculosis Conserved protein 0.0116 0.0365 0.0502
Loa Loa (eye worm) hypothetical protein 0.0057 0.0164 0.016
Echinococcus multilocularis lamin 0.0058 0.0168 0.0168
Trypanosoma cruzi cytochrome P450, putative 0.0106 0.033 0.0321
Brugia malayi larval opioid receptor 0.0102 0.0316 0.0315
Mycobacterium tuberculosis Conserved protein 0.0015 0.0021 0.0025
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0082 0.025 0.0241
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0371 0.1242 0.1716
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.0316 0.0312
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0102 0.0102
Echinococcus granulosus dna polymerase eta 0.0039 0.0102 0.0102
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.0833 0.0829
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0015 0.0019 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Echinococcus granulosus dnaJ subfamily B 0.0469 0.158 0.158
Trichomonas vaginalis set domain proteins, putative 0.0287 0.0953 1
Trichomonas vaginalis diacylglycerol kinase, putative 0.0082 0.025 0.2539
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.292 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.025 0.2539
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.0316 0.0316
Brugia malayi nuclear receptor NHR-88 0.0023 0.0046 0.0045
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0102 0.0316 0.0316
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0004 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0049 0.0226
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0365 0.0356
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) TYRA-2 protein 0.0102 0.0316 0.0312
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0102 0.0316 0.0315
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0009 0.0002
Onchocerca volvulus 0.0012 0.0009 0.0046
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans esterase/lipase LipP 0.0116 0.0365 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0046 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.0316 0.0316
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0198 0.0649 0.6776
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0009 0.0009
Brugia malayi hypothetical protein 0.0239 0.0788 0.0787
Onchocerca volvulus 0.0198 0.0649 0.6799
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0039 0.0042
Brugia malayi diacylglycerol kinase 0.0082 0.025 0.0249
Mycobacterium tuberculosis Conserved protein 0.0116 0.0365 0.0502
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0742 0.2515 0.2512
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0139 0.013
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0256 0.0256
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0049 0.2103
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Echinococcus granulosus sex peptide receptor 0.0102 0.0316 0.0316
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0018 0.0009
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0093
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0008
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0161 0.0152
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0018 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.025 0.0241
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0011 0.0011
Brugia malayi Rhodanese-like domain containing protein 0.0198 0.0649 0.0648
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0046 0.0046
Brugia malayi AKH receptor 0.0102 0.0316 0.0315
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0116 0.0427
Brugia malayi Ceramide kinase 0.0082 0.025 0.0249
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0046 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0046 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0017
Mycobacterium leprae Conserved hypothetical protein 0.0065 0.0191 0.127
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0046 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.0316 0.0316
Trichomonas vaginalis sphingosine kinase, putative 0.0082 0.025 0.2539
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0092
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0021 0.0011
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0037 0.0039
Onchocerca volvulus 0.0116 0.0365 0.3804
Schistosoma mansoni carbonic anhydrase-related 0.0742 0.2515 0.2515
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0011 0.0011
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0019 0.0019
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0075 0.0074
Trypanosoma cruzi diacylglycerol kinase, putative 0.0082 0.025 0.0241
Brugia malayi G protein-coupled receptor F59B2.13 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0021 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0139 0.0189
Schistosoma mansoni carbonic anhydrase-related 0.0742 0.2515 0.2515
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.0381 0.0523
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0242 0.0233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.0015 0.0021 0.0011
Loa Loa (eye worm) glutathione reductase 0.0163 0.0526 0.0522
Onchocerca volvulus 0.0102 0.0316 0.3292
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0116 0.0365 0.0493
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0033 0.002
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0011 0.0011
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0025 0.0024
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi G-protein coupled receptor 0.0102 0.0316 0.0315
Loa Loa (eye worm) beta-lactamase 0.0116 0.0365 0.0361
Brugia malayi putative neuropeptide receptor 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni DNA polymerase eta 0.0039 0.0102 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0341 0.3507
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0017 0.0027 0.0024
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0242 0.0233
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0082 0.025 0.0246
Trypanosoma brucei unspecified product 0.0039 0.0102 0.0093
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0046 0.0041
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0004 0.0004
Onchocerca volvulus 0.0198 0.0649 0.6799
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0046 0.0045
Toxoplasma gondii type I fatty acid synthase, putative 0.0018 0.0029 0.0081
Trypanosoma cruzi diacylglycerol kinase, putative 0.0082 0.025 0.0241
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0033 0.0973
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0015 0.0019 0.001
Trypanosoma cruzi Sphingosine kinase 0.0082 0.025 0.0241
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0017 0.0025 0.005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0009 0.0009
Schistosoma mansoni diacylglycerol kinase theta 0.0082 0.025 0.025
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.0316 0.0312
Echinococcus multilocularis Rhodanese 0.0015 0.0021 0.0021
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.0341 0.0332
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0033 0.0024
Onchocerca volvulus 0.0287 0.0953 1
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0015 0.0019 0.0019
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0161 0.1593
Echinococcus granulosus g-protein coupled receptor 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0021
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0004 0.0004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Plasmodium falciparum carbonic anhydrase 0.0742 0.2515 1
Echinococcus granulosus lamin 0.0058 0.0168 0.0168
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0009 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0033 0.0033
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trichomonas vaginalis apoptosis inducing factor, putative 0.0015 0.0019 0.0082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0102 0.0316 0.0312
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0018 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0033 0.0023
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0106 0.033 0.0445
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0037 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0727 0.2464 0.2464
Toxoplasma gondii thioredoxin reductase 0.0163 0.0526 0.2065
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0082 0.025 0.025
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0382 0.0377
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0076
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0048 0.0134 0.0133
Schistosoma mansoni hypothetical protein 0.0049 0.0135 0.0135
Brugia malayi Pre-SET motif family protein 0.0252 0.0833 0.0832
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0365 0.3759
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.0316 0.0316
Schistosoma mansoni carbonic anhydrase 0.0742 0.2515 0.2515
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0049 0.016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0015 0.0021 0.0004
Loa Loa (eye worm) CYP4Cod1 0.0106 0.033 0.0326
Trypanosoma cruzi As/Sb Reductase, putative 0.0015 0.0021 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0412 0.1384 0.1913
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0033 0.0028
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0019 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.0316 0.0316
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0064 0.0064
Echinococcus multilocularis Diacylglycerol kinase theta 0.0082 0.025 0.025
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0102 0.0117
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.292 1 1
Echinococcus granulosus fmrfamide receptor 0.0102 0.0316 0.0316
Onchocerca volvulus 0.0012 0.0009 0.0046
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0015 0.0019 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0161 0.021
Mycobacterium ulcerans hypothetical protein 0.0015 0.0021 0.0016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0065 0.0191 0.0262
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.0316 0.0316
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0594 0.0594
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0082 0.025 0.025
Echinococcus multilocularis dnaJ subfamily B 0.0469 0.158 0.158
Leishmania major hypothetical protein, conserved 0.0015 0.0021 0.0011
Mycobacterium tuberculosis Probable hydrolase 0.0116 0.0365 0.0502
Schistosoma mansoni cytochrome P450 0.0065 0.0191 0.0191
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0742 0.2515 0.2514
Onchocerca volvulus 0.0102 0.0316 0.3292
Echinococcus multilocularis neuropeptide receptor A26 0.0657 0.2225 0.2225
Loa Loa (eye worm) thioredoxin reductase 0.0163 0.0526 0.0522
Schistosoma mansoni nuclear receptor 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0014 0.0017 0.002
Brugia malayi Cytochrome P450 family protein 0.0241 0.0795 0.0795
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0015 0.0019 0.0041
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.0341 0.0341
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0161 0.0608
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0019 0.001
Plasmodium vivax glutathione reductase, putative 0.0163 0.0526 1
Plasmodium vivax diacylglycerol kinase, putative 0.0082 0.025 0.4667
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Loa Loa (eye worm) fatty acid synthase 0.0025 0.0053 0.0049
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0009 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.0365 0.3759
Schistosoma mansoni hypothetical protein 0.0082 0.0249 0.0249
Brugia malayi ecdysone receptor 0.0011 0.0004 0.0003
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1618 0.5527 0.5527
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi hypothetical protein 0.0153 0.0492 0.0491
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0018 0.0021
Loa Loa (eye worm) carbonic anhydrase 3 0.292 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Brugia malayi hypothetical protein 0.0011 0.0004 0.0003
Loa Loa (eye worm) acyl carrier protein 0.0012 0.0007 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0594 0.0594
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0036 0.0091 0.0091
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0116 0.0365 0.0502
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0019 0.0013
Echinococcus granulosus serotonin receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.025 0.0322
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0098
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Mycobacterium leprae putative cytochrome p450 0.0065 0.0191 0.127
Mycobacterium ulcerans hypothetical protein 0.2113 0.7228 1
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.0015 0.0021 0.0129
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0009 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0018 0.0021
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.0381 0.1484
Toxoplasma gondii exonuclease III APE 0.0019 0.0033 0.0096
Onchocerca volvulus 0.0102 0.0316 0.3292
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0051 0.0068
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0019 0.001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.0381 0.0381
Schistosoma mansoni sphingosine kinase A B 0.2113 0.7228 0.7228
Loa Loa (eye worm) hypothetical protein 0.0085 0.0259 0.0255
Schistosoma mansoni neuropeptide receptor 0.0102 0.0316 0.0316
Schistosoma mansoni biogenic amine receptor 0.0102 0.0316 0.0316
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0161 0.0161
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0168 0.0167
Brugia malayi Myosin head containing protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0039 0.0159
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.0015 0.0021 0.0011
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0059 0.0069
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0046 0.0046
Mycobacterium tuberculosis Conserved protein 0.0116 0.0365 0.0502
Echinococcus multilocularis serotonin receptor 0.0102 0.0316 0.0316
Onchocerca volvulus 0.0038 0.0099 0.0996
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0015 0.0021 0.0025
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0102 0.0093
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0371 0.1242 0.1716
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0019 0.001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0018 0.0009
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0033 0.0096
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0472 0.0472
Brugia malayi neuropeptide F receptor 0.0102 0.0316 0.0315
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0065 0.0191 0.0262
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0019 0.001
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0011 0.0007
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0004
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0019 0.0041
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0161 0.0152
Echinococcus multilocularis glutamate synthase 0.0015 0.0019 0.0019
Schistosoma mansoni neuropeptide receptor 0.0102 0.0316 0.0316
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0381 0.0514
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0018 0.003 0.0038
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0015 0.0019 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0033 0.0033
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0102 0.0316 0.0316
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0015 0.0019 0.0001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0116 0.0365 0.0365
Trichomonas vaginalis cdc25b, putative 0.0198 0.0649 0.6776
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0102 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0093
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0004
Brugia malayi hypothetical protein 0.008 0.0242 0.0241
Brugia malayi Patched family protein 0.0012 0.0009 0.0008
Mycobacterium ulcerans polyketide synthase Pks13 0.0038 0.0097 0.0121
Brugia malayi hypothetical protein 0.0082 0.025 0.0249
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0004 0.0004
Brugia malayi Melatonin receptor type 1A 0.0102 0.0316 0.0315
Trypanosoma brucei unspecified product 0.0027 0.006 0.0051
Echinococcus multilocularis Niemann Pick C1 protein 0.0283 0.0939 0.0939
Plasmodium falciparum thioredoxin reductase 0.0056 0.0161 0.0608
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0004 0.0003
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0102 0.0316 0.0316
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.0015 0.0021 0.002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0033 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0371 0.1242 0.8959
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0021 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0089 0.012
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0198 0.0649 0.6776
Brugia malayi hypothetical protein 0.0102 0.0316 0.0315
Brugia malayi hypothetical protein 0.0012 0.0009 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0025 0.0025
Onchocerca volvulus 0.0037 0.0094 0.0943
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Brugia malayi cytochrome P450 0.0065 0.0191 0.019
Toxoplasma gondii cytochrome p450 superfamily protein 0.0065 0.0191 0.0729
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0046 0.0046
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0412 0.1384 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0019 0.0041
Toxoplasma gondii diacylglycerol kinase, putative 0.0082 0.025 0.0964
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0139 0.018
Onchocerca volvulus 0.0012 0.0009 0.0046
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.0015 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0065 0.0191 0.0262
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0139 0.0189
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0025 0.0054 0.0071
Echinococcus granulosus g protein coupled receptor 0.0102 0.0316 0.0316
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0161 0.0152
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0092
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0049 0.0055
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.0316 0.0316
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0742 0.2515 0.2512
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Entamoeba histolytica rodhanase-like domain containing protein 0.0015 0.0021 0.0004
Leishmania major diacylglycerol kinase-like protein 0.0082 0.025 0.0241
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0046 0.0046
Mycobacterium ulcerans hypothetical protein 0.0116 0.0365 0.0493
Schistosoma mansoni opsin-like receptor 0.0102 0.0316 0.0316
Entamoeba histolytica rodhanase-like domain containing protein 0.0198 0.0649 0.0875
Onchocerca volvulus 0.0102 0.0316 0.3292
Echinococcus multilocularis somatostatin receptor 0.0102 0.0316 0.0316
Entamoeba histolytica thioredoxin reductase, putative 0.0015 0.0019 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0046 0.0046
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0065 0.0191 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0093
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.0316 0.0316
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0116 0.0427
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0102 0.0316 0.0315
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0033 0.0042
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0015 0.0021 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0089 0.012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0019 0.0082
Brugia malayi ORL1-like opioid receptor 0.0102 0.0316 0.0315
Echinococcus granulosus Niemann Pick C1 protein 0.0283 0.0939 0.0939
Trichomonas vaginalis cdc25a, putative 0.0015 0.0021 0.0101
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0161 0.0152
Leishmania major As/Sb Reductase 0.0015 0.0021 0.0011
Onchocerca volvulus 0.0015 0.0021 0.0172
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0046 0.0436
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0015 0.0021 0.0025
Trypanosoma cruzi As/Sb Reductase, putative 0.0015 0.0021 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0065 0.0191 0.0262
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.0341 0.0337
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0033 0.0024
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.011 0.1054
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0065 0.0191 0.0252
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0102 0.0316 0.0316
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0025 0.0054 0.0264
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0015 0.0019 0.0288
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0102 0.0101
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0198 0.0649 0.0649
Schistosoma mansoni lamin 0.0058 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0116 0.0365 0.0361
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0594 0.0594
Leishmania major hypothetical protein, unknown function 0.0015 0.0021 0.0011
Onchocerca volvulus 0.0102 0.0316 0.3292
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0018 0.0017
Echinococcus multilocularis 0.0065 0.0191 0.0191
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.0015 0.0021 0.0232
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0015
Brugia malayi ecdysteroid receptor 0.0023 0.0046 0.0045
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0198 0.0649 0.6776
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0096 0.012
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0019 0.0041
Echinococcus multilocularis carbonic anhydrase 0.0742 0.2515 0.2515
Mycobacterium ulcerans beta-lactamase 0.0116 0.0365 0.0493
Mycobacterium ulcerans dehydrogenase 0.0015 0.0019 0.0013
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0054 0.0062
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0015 0.0021 0.0011
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0065 0.0191 0.0252
Loa Loa (eye worm) hypothetical protein 0.0198 0.0649 0.0645
Mycobacterium leprae Probable polyketide synthase Pks1 0.0027 0.0059 0.0303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.0316 0.0316
Plasmodium vivax SET domain protein, putative 0.0037 0.0094 0.1644
Loa Loa (eye worm) hypothetical protein 0.0102 0.0316 0.0312
Plasmodium vivax ferrodoxin reductase, putative 0.0015 0.0019 0.0196
Plasmodium falciparum glutathione reductase 0.0056 0.0161 0.0608

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7943 uM PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.7783 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: HTS Assay for Compounds that Act as Enhancers of the Vanilloid Receptor 1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488988] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774] ChEMBL. No reference
Potency (functional) = 37.933 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Human Peripheral Myelin Protein 22 (PMP22) Expression/Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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