Detailed information for compound 313892

Basic information

Technical information
  • TDR Targets ID: 313892
  • Name: 5-tert-butyldithiole-3-thione
  • MW: 190.349 | Formula: C7H10S3
  • H donors: 0 H acceptors: 0 LogP: 2.85 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(c1ssc(=S)c1)(C)C
  • InChi: 1S/C7H10S3/c1-7(2,3)5-4-6(8)10-9-5/h4H,1-3H3
  • InChiKey: UOJANZHJPTXZPP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-tert-butyl-3-dithiolethione
  • 5-tert-butyl-1,2-dithiole-3-thione
  • 5-tert-butyl-3H-1,2-dithiole-3-thione
  • 29507-64-0
  • 3H-1,2-Dithiole-3-thione, 5-(1,1-dimethylethyl)-
  • 3H-1,2-Dithiole-3-thione,5-(1,1-dimethylethyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0138 0.0597 0.3818
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0094 0.0336
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.015
Brugia malayi hypothetical protein 0.0008 0.0005 0.0011
Toxoplasma gondii pyruvate kinase PyKII 0.002 0.0059 0.0333
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.001 0.0018
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0138 0.0597 0.0595
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0532 0.2392 0.5754
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0005 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.0015 0.0038 0.0213
Echinococcus granulosus Sugar transporter ERD6 protein 0.001 0.0013 0.0012
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.0193 0.1232
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0027 0.0091 0.0219
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0007 0.0002 0.0005
Giardia lamblia Hexose transporter 0.001 0.0013 0.0023
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Plasmodium vivax pyruvate kinase, putative 0.0039 0.0144 0.0604
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0005 0.0018
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0138 0.0597 0.1435
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Brugia malayi POT family protein 0.0082 0.0344 0.0828
Trypanosoma cruzi hexose transporter 0.001 0.0013 0.0086
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0007 0.0002 0.0006
Onchocerca volvulus 0.0008 0.0005 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0094 0.0335
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Schistosoma mansoni pyruvate kinase 0.0039 0.0144 0.0144
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.0184 0.0808 0.2889
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.046 0.0797
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0005 0.0003
Mycobacterium tuberculosis Probable reductase 0.01 0.0424 0.1515
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0015 0.0038 0.009
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0008 0.0005 0.0011
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0011 0.0019 0.0046
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Schistosoma mansoni DNA helicase recq5 0.0009 0.001 0.001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0024 0.0023
Mycobacterium leprae Probable pyruvate kinase PykA 0.0039 0.0144 0.0511
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0138 0.0597 0.1033
Schistosoma mansoni lamin 0.0031 0.0111 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.045
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.0469 0.1129
Loa Loa (eye worm) hypothetical protein 0.0049 0.0192 0.0462
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0571 0.0571
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0005 0.0003
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0013 0.0086
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0212 0.0932 0.2243
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0008 0.0005 0.0003
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.001 0.0009
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0116 0.0498 0.0498
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0015 0.0038 0.0157
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Plasmodium vivax hexose transporter 0.001 0.0013 0.0056
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0011
Onchocerca volvulus 0.0008 0.0005 0.001
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.0506 0.0506
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Trypanosoma cruzi sugar transporter, putative 0.001 0.0013 0.0086
Mycobacterium tuberculosis Probable dehydrogenase 0.0008 0.0005 0.0016
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0111 0.0268
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.007 0.0069
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.001 0.0013 0.0048
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.001 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Echinococcus multilocularis dna polymerase eta 0.0022 0.007 0.0069
Loa Loa (eye worm) patched family protein 0.0007 0.00000022915 0.00000055132
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0108 0.0613
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.001 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0094 0.0336
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0092 0.0588
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0005 0.0034
Schistosoma mansoni sugar transporter 0.001 0.0013 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0074 0.0307 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0672 0.3029 0.5257
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.046 0.0799
Onchocerca volvulus 0.0031 0.0111 0.0235
Plasmodium falciparum hexose transporter 0.001 0.0013 0.0056
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0038 0.024
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0026
Brugia malayi Cytochrome P450 family protein 0.0013 0.0027 0.0065
Trichomonas vaginalis glucose transporter, putative 0.001 0.0013 0.0021
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Leishmania major cytochrome p450-like protein 0.0013 0.0027 0.0172
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Leishmania major myo-inositol/proton symporter (MIT) 0.001 0.0013 0.0086
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0032 0.0115 0.0197
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0045 0.0108
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0005 0.0029
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0025
Brugia malayi Myosin head containing protein 0.0007 0.00000022915 0.00000055132
Brugia malayi MAP kinase sur-1 0.0108 0.046 0.1108
Onchocerca volvulus 0.0008 0.0005 0.001
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.046 0.0459
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni lamin 0.0031 0.0111 0.0111
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0919 0.4156 1
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0032 0.0115 0.0651
Leishmania major 3-keto-dihydrosphingosine reductase 0.0008 0.0005 0.0029
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.0506 0.3235
Loa Loa (eye worm) hypothetical protein 0.0022 0.007 0.0169
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0276
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.046 0.0797
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.0005 0.0005
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Schistosoma mansoni transcription factor btf3 0.0078 0.0324 0.0324
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0058 0.0241
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0015 0.0038 0.0157
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0037 0.0036
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0007 0.0002 0.0005
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0005 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0137 0.0592 0.1425
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.007 0.045
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0008 0.0005 0.0026
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0015 0.0038 0.024
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.01 0.0424 0.151
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0027 0.0172
Toxoplasma gondii sugar transporter ST1 0.001 0.0013 0.0076
Echinococcus multilocularis pyruvate kinase 0.0039 0.0144 0.0143
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0026
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0008 0.0005 0.0019
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0015 0.0038 0.024
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Leishmania major DNA polymerase eta, putative 0.0022 0.007 0.045
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Onchocerca volvulus 0.001 0.0013 0.0028
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0192 0.0191
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0008 0.0005 0.0016
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0008 0.0005 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0039 0.0247
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.046 0.0459
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0211 0.0507
Loa Loa (eye worm) sugar transporter 0.001 0.0013 0.0032
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.007 0.0069
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0033 0.0031
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0008 0.0005 0.0011
Leishmania major trypanothione reductase 0.0044 0.0168 0.1076
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0094 0.0226
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0007 0.0002 0.001
Echinococcus granulosus solute carrier family 22 0.001 0.0013 0.0012
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0486 0.1169
Loa Loa (eye worm) hypothetical protein 0.0114 0.049 0.1179
Schistosoma mansoni glucose transport protein 0.001 0.0013 0.0013
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0532 0.2392 0.4151
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0008 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0052
Giardia lamblia Pyruvate kinase 0.0039 0.0144 0.0251
Echinococcus granulosus GPCR family 2 0.0018 0.0052 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0572 0.0572
Brugia malayi intermediate filament protein 0.0031 0.0111 0.0268
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.046 0.1108
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0008 0.0005 0.0003
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0005 0.0016
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0074 0.0307 0.0531
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0005 0.0034
Leishmania major basic transcription factor 3a, putative 0.0078 0.0324 0.2074
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Echinococcus granulosus oxidoreductase 0.0008 0.0005 0.0003
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0032 0.0115 0.0197
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0032 0.0115 0.0197
Trypanosoma brucei lanosterol synthase 0.0032 0.0115 0.0735
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0039 0.0247
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.0005 0.0005
Onchocerca volvulus 0.0138 0.0597 0.126
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0013 0.0032
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0005 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.0571 0.057
Trypanosoma brucei glucose transporter 2A 0.001 0.0013 0.0086
Echinococcus granulosus pyruvate kinase 0.0039 0.0144 0.0143
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0005 0.0016
Onchocerca volvulus 0.001 0.0013 0.0028
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0005 0.0029
Leishmania major hypothetical protein, conserved 0.001 0.0013 0.0086
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0015 0.0038 0.1178
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.0841
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0106 0.068
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0211 0.0209
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0015 0.0038 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0276
Echinococcus granulosus L aminoadipate semialdehyde 0.0264 0.1173 0.1172
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0023 0.0037
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0007 0.0002 0.0006
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.0002 0.001
Leishmania major glucose transporter/membrane transporter D2, putative 0.001 0.0013 0.0086
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0532 0.2392 0.5754
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0132 0.0572 0.057
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.0002 0.001
Brugia malayi Thioredoxin reductase 0.0044 0.0168 0.0404
Mycobacterium ulcerans hypothetical protein 0.0028 0.0094 0.0336
Schistosoma mansoni hypothetical protein 0.0047 0.0184 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0304 0.0304
Echinococcus multilocularis solute carrier family 22 0.001 0.0013 0.0012
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0013 0.0032
Echinococcus multilocularis cpg binding protein 0.0032 0.0113 0.0111
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0005 0.0003
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0005 0.0003
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0264 0.1173 0.1173
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0024
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0005 0.001
Echinococcus granulosus pyruvate kinase 0.002 0.0059 0.0057
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0007 0.0002 0.0009
Trypanosoma brucei trypanothione reductase 0.0044 0.0168 0.1076
Giardia lamblia Hypothetical protein 0.0008 0.0005 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Toxoplasma gondii hypothetical protein 0.0007 0.00000022915 0.0000012995
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0049 0.0049
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0108 0.0185
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0005 0.0029
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0106 0.068
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0074 0.0307 0.1098
Mycobacterium ulcerans pyruvate kinase 0.0039 0.0144 0.0516
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0032 0.0115 0.0113
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0486 0.1169
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0094 0.0601
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.046 0.0797
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0029
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni SET domain protein 0.0007 0.0001 0.0001
Onchocerca volvulus 0.001 0.0013 0.0028
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0138 0.0597 0.3818
Loa Loa (eye worm) hypothetical protein 0.0015 0.0035 0.0083
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0008 0.0005 0.0026
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0005 0.0034
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0211 0.0209
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0007 0.0002 0.0006
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0008 0.0005 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0012 0.0074
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0005 0.0029
Echinococcus granulosus Niemann Pick C1 protein 0.0114 0.049 0.0488
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0007 0.0002 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.1563 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0105 0.0253
Brugia malayi Patched related family protein 10 0.0007 0.00000022915 0.00000055132
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.001 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0224 0.0539
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0029
Brugia malayi Sugar transporter family protein 0.001 0.0013 0.0032
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0027 0.0172
Echinococcus granulosus transcription factor btf3 0.0078 0.0324 0.0323
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0211 0.0211
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0015 0.0038 0.0157
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0013 0.0032
Onchocerca volvulus 0.0031 0.0111 0.0235
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0144 0.0248
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0506 0.0504
Toxoplasma gondii sugar transporter ST3 0.001 0.0013 0.0076
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0005 0.0026
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0111 0.0268
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0111 0.0268
Leishmania major DNA polymerase kappa, putative 0.0022 0.007 0.045
Mycobacterium ulcerans acetyl-CoA synthetase 0.0008 0.0005 0.0019
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0007 0.0002 0.0006
Schistosoma mansoni carbonyl reductase 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi glutathione reductase 0.0044 0.0168 0.0404
Trypanosoma cruzi hexose transporter, putative 0.001 0.0013 0.0086
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Leishmania major pteridine reductase 1 0.0008 0.0005 0.0029
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0193 0.1232
Schistosoma mansoni hypothetical protein 0.001 0.0013 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0106 0.0185
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0005 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Brugia malayi Pre-SET motif family protein 0.0919 0.4156 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0045 0.0108
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0304 0.0302
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) pyruvate kinase 0.0008 0.0005 0.0013
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0011
Trypanosoma brucei transcription factor BTF3, putative 0.0078 0.0324 0.2074
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0007 0.0002 0.0005
Onchocerca volvulus 0.001 0.0013 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Mycobacterium ulcerans carveol-like dehydrogenase 0.0008 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Onchocerca volvulus 0.001 0.0013 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Plasmodium falciparum basic transcription factor 3b, putative 0.0078 0.0324 0.1355
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0005 0.0034
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.0571 0.3657
Schistosoma mansoni carbonyl reductase 0.0008 0.0005 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0159 0.0159
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0144 0.0348
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0232 0.0559
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.0168 0.0404
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0062 0.0913
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Brugia malayi major facilitator superfamily protein 0.001 0.0013 0.0032
Toxoplasma gondii hypothetical protein 0.0394 0.1763 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.0005 0.0011
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.045
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0012 0.0022 0.0052
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.015
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0008 0.0005 0.0016
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0052 0.0125
Mycobacterium tuberculosis Probable dehydrogenase 0.01 0.0424 0.1515
Echinococcus multilocularis transcription factor btf3 0.0078 0.0324 0.0323
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0007 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0032 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0052
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Echinococcus granulosus steroid dehydrogenase 0.0008 0.0005 0.0003
Plasmodium falciparum geranylgeranyltransferase, putative 0.0032 0.0115 0.048
Chlamydia trachomatis pyruvate kinase 0.0039 0.0144 0.3965
Brugia malayi CHE-14 protein 0.0049 0.0192 0.0462
Toxoplasma gondii sugar transporter ST2 0.001 0.0013 0.0076
Loa Loa (eye worm) dehydrogenase 0.0008 0.0005 0.0011
Trichomonas vaginalis myo-inositol transporter, putative 0.001 0.0013 0.0021
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0132 0.0572 0.3242
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0132 0.0572 0.057
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0092 0.0521
Entamoeba histolytica hypothetical protein 0.0078 0.0324 0.056
Brugia malayi hypothetical protein 0.0027 0.0092 0.0221
Giardia lamblia Rab geranylgeranyltransferase 0.0532 0.2392 0.4152
Leishmania major mitochondrial DNA polymerase beta 0.035 0.1563 1
Brugia malayi Pyruvate kinase, muscle isozyme 0.0039 0.0144 0.0348
Giardia lamblia Rab geranylgeranyltransferase 0.0032 0.0115 0.0199
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0005 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0651
Trypanosoma cruzi hexose transporter, putative 0.001 0.0013 0.0086
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0008 0.0005 0.0003
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.007 0.007
Echinococcus multilocularis retinol dehydrogenase 13 0.0008 0.0005 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0211 0.0209
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0005 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0723 0.4626
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0108 0.0185
Trypanosoma cruzi protein farnesyltransferase, putative 0.0032 0.0115 0.0735
Echinococcus multilocularis survival motor neuron protein 1 0.0275 0.1221 0.1219
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0023 0.0145
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0027 0.0065
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0108 0.0185
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0012 0.0024 0.0023
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0044 0.0168 0.06
Loa Loa (eye worm) ICD-1 protein 0.0078 0.0324 0.078
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.046 0.2947
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0032 0.0115 0.048
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0943 0.4263 0.4262
Brugia malayi Pre-SET motif family protein 0.0132 0.0572 0.1375
Schistosoma mansoni hypothetical protein 0.0056 0.0224 0.0224
Echinococcus granulosus Solute carrier family 22 5 0.1046 0.4735 0.4734
Schistosoma mansoni sugar transporter 0.001 0.0013 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.1563 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Plasmodium falciparum pyruvate kinase 2 0.002 0.0059 0.0246
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0137 0.0592 0.0591
Brugia malayi hypothetical protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni hypothetical protein 0.0047 0.0184 0.0184
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0008 0.0005 0.0005
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0144 0.0348
Trypanosoma cruzi lanosterol synthase, putative 0.0032 0.0115 0.0735
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0094 0.0226
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0486 0.1736
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.0002 0.001
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0007 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Onchocerca volvulus 0.0008 0.0005 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Echinococcus granulosus bloom syndrome protein 0.0022 0.007 0.0068
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.046 0.2947
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0008 0.0005 0.0019
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0008 0.0005 0.0003
Brugia malayi oxidoreductase 0.0008 0.0005 0.0011
Leishmania major glucose transporter, lmgt2 0.001 0.0013 0.0086
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0486 0.0841
Loa Loa (eye worm) glutathione reductase 0.0044 0.0168 0.0404
Giardia lamblia Rab geranylgeranyltransferase 0.0138 0.0597 0.1036
Trypanosoma cruzi hypothetical protein, conserved 0.0138 0.0597 0.3818
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.001 0.0043
Entamoeba histolytica hypothetical protein 0.0008 0.0005 0.0005
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0106 0.0256
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0005 0.0003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0058
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0052 0.005
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0304 0.0304
Schistosoma mansoni hypothetical protein 0.0047 0.0184 0.0184
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0192 0.0191
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0571 0.2043
Echinococcus multilocularis pyruvate kinase 0.002 0.0059 0.0057
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0532 0.2392 0.239
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.0571 0.2042
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0032 0.0115 0.0113
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0008 0.0005 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.016 0.0699 0.0699
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0008 0.0005 0.001
Echinococcus granulosus expressed conserved protein 0.0108 0.0458 0.0457
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Echinococcus granulosus pyruvate kinase 0.002 0.0059 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.015
Plasmodium falciparum lipid/sterol:H+ symporter 0.0007 0.00000022915 0.00000095812
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0005 0.0034
Brugia malayi hypothetical protein 0.0275 0.1221 0.2937
Onchocerca volvulus 0.001 0.0013 0.0028
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0621 0.2798 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0249 0.1415
Onchocerca volvulus 0.0008 0.0005 0.001
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0008 0.0005 0.0016
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0005 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0193 0.1232
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0005 0.0029
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi Niemann-Pick C1 protein precursor 0.0114 0.049 0.1179
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.0005 0.0011
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0032 0.0115 0.0115
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Schistosoma mansoni cpg binding protein 0.0032 0.0113 0.0113
Brugia malayi protein C24B5.3 0.0007 0.00000022915 0.00000055132
Entamoeba histolytica transcription factor BTF3, putative 0.0078 0.0324 0.056
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0007 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0025
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0005 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Schistosoma mansoni glucose transporter 0.001 0.0013 0.0013
Onchocerca volvulus 0.0008 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0029
Plasmodium vivax sugar transporter, putative 0.001 0.0013 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0324 0.056
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Trypanosoma brucei sugar transporter, putative 0.001 0.0013 0.0086
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0015 0.0038 0.0134
Entamoeba histolytica hypothetical protein 0.0042 0.0159 0.0273
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0007 0.0002 0.0006
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0032 0.0115 0.0651
Plasmodium falciparum flap endonuclease 1 0.003 0.0106 0.0445
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1271 0.576 1
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0008 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0058 0.0232 0.0559
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.007 0.0169
Loa Loa (eye worm) hypothetical protein 0.0028 0.0094 0.0226
Toxoplasma gondii patched family protein 0.0007 0.00000022915 0.0000012995
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0013 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Echinococcus granulosus dna polymerase kappa 0.0022 0.007 0.0069
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Schistosoma mansoni sugar transporter 0.001 0.0013 0.0013
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0486 0.3108
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0007 0.0002 0.0006
Schistosoma mansoni cpg binding protein 0.003 0.0105 0.0105
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0057 0.0204
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0026
Schistosoma mansoni carbonyl reductase 0.0008 0.0005 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.0841
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.045
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0115 0.0735
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0024 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.007 0.0119
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0475 0.1697
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.0348
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0144 0.0305
Echinococcus multilocularis Niemann Pick C1 protein 0.0164 0.0714 0.0712
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0005 0.0018
Echinococcus granulosus Niemann Pick C1 protein 0.0164 0.0714 0.0712
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0005 0.0003
Echinococcus multilocularis solute carrier family 22 0.001 0.0013 0.0012
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0621 0.2798 1
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Echinococcus granulosus solute carrier family 22 0.001 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.046 0.0459
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Trypanosoma cruzi lanosterol synthase, putative 0.0032 0.0115 0.0735
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0242 0.1546
Echinococcus granulosus histone lysine methyltransferase setb 0.0132 0.0572 0.057
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Toxoplasma gondii thioredoxin reductase 0.0044 0.0168 0.0953
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0011 0.0019 0.0046
Echinococcus multilocularis lamin 0.0031 0.0111 0.011
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0005 0.0003
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.046 0.0459
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Brugia malayi hypothetical protein 0.0008 0.0005 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0005 0.0016
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0074 0.0307 0.1742
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0008 0.0005 0.0013
Brugia malayi Patched related family protein 12 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.007 0.0169
Trypanosoma cruzi hexose transporter, putative 0.001 0.0013 0.0086
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Plasmodium falciparum thioredoxin reductase 0.0015 0.0038 0.0157
Schistosoma mansoni hypothetical protein 0.0042 0.0159 0.0159
Onchocerca volvulus 0.0132 0.0572 0.1207
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0111 0.0475 0.1697
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0138 0.0597 0.3818
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Schistosoma mansoni sugar transporter 0.001 0.0013 0.0013
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0015 0.0038 0.0038
Toxoplasma gondii hypothetical protein 0.0056 0.0226 0.1279
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0137 0.0592 0.0591
Plasmodium vivax steroid dehydrogenase, putative 0.0008 0.0005 0.0019
Trichomonas vaginalis sugar transport protein, putative 0.001 0.0013 0.0021
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.001 0.0013 0.0013
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Leishmania major glucose transporter, lmgt1 0.001 0.0013 0.0086
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.007 0.045
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.045
Loa Loa (eye worm) RecQ helicase 0.0022 0.007 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0192 0.0331
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0015 0.0038 0.0036
Schistosoma mansoni patched 1 0.0049 0.0192 0.0192
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0005 0.0018
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0008 0.0005 0.0029
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.007 0.0119
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0486 0.0484
Trichomonas vaginalis glutathione reductase, putative 0.0015 0.0038 0.0063
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0036 0.0206
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0032 0.0115 0.0276
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0005 0.0005
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.023 0.023
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0532 0.2392 0.239
Onchocerca volvulus 0.0007 0.0001 0.0003
Trypanosoma cruzi glucose transporter, putative 0.001 0.0013 0.0086
Echinococcus multilocularis lamin dm0 0.0031 0.0111 0.011
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.0005 0.0005
Onchocerca volvulus 0.0008 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.001 0.0013 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0307 0.1966
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0013 0.0032
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.0002 0.001
Schistosoma mansoni pyruvate kinase 0.0039 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0092 0.0588
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.0841
Plasmodium vivax geranylgeranyltransferase, putative 0.0032 0.0115 0.048
Trypanosoma cruzi transcription factor btf3, putative 0.0078 0.0324 0.2074
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0008 0.0005 0.0016
Brugia malayi hypothetical protein 0.0007 0.00000022915 0.00000055132
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0094 0.0601
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0005 0.0016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0127 0.0547 0.0545
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Brugia malayi Retinol dehydrogenase 12 0.0008 0.0005 0.0011
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0008 0.0005 0.0013
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0307 0.1284
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0005 0.0006
Onchocerca volvulus 0.001 0.0013 0.0028
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0094 0.0336
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.0268
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0027 0.0065
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0015 0.0038 0.024
Toxoplasma gondii pyruvate kinase PyK1 0.0039 0.0144 0.0819
Plasmodium falciparum thioredoxin reductase 0.0044 0.0168 0.0703
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0032 0.0115 0.048
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0032 0.0115 0.0735
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0621 0.2798 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.046 0.2947
Echinococcus granulosus flap endonuclease 1 0.003 0.0106 0.0105
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.0571 0.3241
Toxoplasma gondii patched family protein 0.0007 0.00000022915 0.0000012995
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0052
Loa Loa (eye worm) aldehyde dehydrogenase 0.0007 0.0002 0.0004
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.001 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0005 0.0019
Mycobacterium ulcerans oxidoreductase 0.0008 0.0005 0.0016
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.0171 0.0169
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0108 0.2618
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Trypanosoma brucei unspecified product 0.0022 0.007 0.045
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0094 0.033
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0324 0.056
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0144 0.0305
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0149 0.0358
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0038 0.024
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0108 0.0613
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0193 0.1232
Loa Loa (eye worm) hypothetical protein 0.0275 0.1221 0.2937
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0074 0.0307 1
Plasmodium vivax thioredoxin reductase, putative 0.0044 0.0168 0.0703
Loa Loa (eye worm) dehydrogenase 0.0008 0.0005 0.0011
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.0005 0.003
Loa Loa (eye worm) POT family protein 0.0082 0.0344 0.0828
Treponema pallidum fructose-bisphosphate aldolase 0.1271 0.576 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0532 0.2392 0.4151
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0212 0.0932 0.0931
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0005 0.0013
Echinococcus multilocularis synaptic vesicle 2 protein 0.001 0.0013 0.0012
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0007 0.0002 0.0006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0008 0.0005 0.0019
Schistosoma mansoni hypothetical protein 0.0197 0.0866 0.0866
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0005 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0094 0.016
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0032 0.0115 0.0197
Echinococcus granulosus hypothetical protein 0.0008 0.0005 0.0003
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0008 0.0005 0.0011
Brugia malayi aldehyde dehydrogenase 0.0007 0.0002 0.0004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Echinococcus granulosus WW domain containing oxidoreductase 0.0008 0.0005 0.0003
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0094 0.033
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0094 0.0226
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0108 0.0613
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Onchocerca volvulus 0.0008 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Mycobacterium ulcerans short-chain type oxidoreductase 0.0008 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.0047 0.0184 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Loa Loa (eye worm) patched family protein 0.0007 0.00000022915 0.00000055132
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0005 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Leishmania major pyruvate kinase 0.0039 0.0144 0.0925
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0062 0.026
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0062 0.026
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0304 0.0731
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.007 0.0251
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0025
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.0005 0.0011
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0015 0.0038 0.1178
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.001 0.0013 0.039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0038 0.024
Brugia malayi hypothetical protein 0.001 0.0013 0.0032
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0008 0.0005 0.0016
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0032 0.0115 0.0276
Trichomonas vaginalis glucose transporter, putative 0.001 0.0013 0.0021
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0005 0.0005
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0007 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0264 0.1173 0.2822
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.046 0.0797
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Brugia malayi hypothetical protein 0.0042 0.0159 0.0382
Schistosoma mansoni flap endonuclease-1 0.0027 0.0093 0.0093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0137 0.0592 0.0591
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0005 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0013 0.0032
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0486 0.1169
Echinococcus multilocularis Sugar transporter ERD6 protein 0.001 0.0013 0.0012
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0212 0.0932 0.1616
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0052 0.0125
Entamoeba histolytica pyruvate kinase, putative 0.0027 0.0091 0.0156
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.0005 0.0011
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.046 0.2947
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0005 0.0018
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.007 0.0168
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0015 0.0038 0.0134
Giardia lamblia Sugar-proton symporter 0.001 0.0013 0.0023
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0005 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0094 0.016
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0005 0.0018
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0307 0.1284
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0184 0.0808 0.2888
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0486 0.3108
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0094 0.016
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0111 0.0475 0.1697
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0115 0.0735
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0094 0.0336
Toxoplasma gondii carbonyl reductase 1, putative 0.0008 0.0005 0.0026
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0026
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0005 0.001
Toxoplasma gondii NAC domain-containing protein 0.0078 0.0324 0.1838
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0304 0.0731
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0304 0.0304
Echinococcus granulosus pyruvate kinase 0.0039 0.0144 0.0143
Echinococcus granulosus synaptic vesicle 2 protein 0.001 0.0013 0.0012
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0138 0.0597 0.1033
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0138 0.0597 0.0595
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.046 0.2947
Mycobacterium tuberculosis Putative ferredoxin reductase 0.01 0.0424 0.1515
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.045
Brugia malayi CXXC zinc finger family protein 0.003 0.0105 0.0253
Echinococcus multilocularis dna polymerase kappa 0.0022 0.007 0.0069
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0197
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0007 0.0002 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0005 0.0019
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0007 0.0002 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0005 0.0016
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0004
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0144 0.0925
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0024 0.0024
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0094 0.0335
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.007 0.045
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0032 0.0115 0.048
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Schistosoma mansoni hypothetical protein 0.0007 0.0002 0.0002
Mycobacterium ulcerans oxidoreductase 0.0008 0.0005 0.0016
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0005 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0571 0.2043
Echinococcus granulosus survival motor neuron protein 1 0.0275 0.1221 0.1219
Echinococcus multilocularis GPCR, family 2 0.0018 0.0052 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0324 0.056
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.0841
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0108 0.0452
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.0506 0.1216
Loa Loa (eye worm) hypothetical protein 0.0057 0.023 0.0554
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.006 0.0243 0.0583
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0092 0.0384
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0506 0.0504
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0092 0.0588
Plasmodium vivax patched family protein, putative 0.0007 0.00000022915 0.00000095812
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0137 0.0592 0.0591
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0159 0.0157
Trypanosoma brucei unspecified product 0.0015 0.0039 0.0247
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0106 0.0603
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.0005 0.0005
Echinococcus multilocularis solute carrier family 22 0.001 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0012 0.0024 0.0024
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0013 0.0086
Echinococcus multilocularis tumor protein p63 0.0393 0.1758 0.1757
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0138 0.0597 0.1435
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0144 0.0248
Brugia malayi Aldehyde dehydrogenase protein 4 0.0007 0.0002 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Echinococcus multilocularis oxidoreductase 0.0008 0.0005 0.0003
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.0005 0.0011
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0506 0.1807
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi major facilitator superfamily protein 0.001 0.0013 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Mycobacterium leprae Probable oxidoreductase 0.0008 0.0005 0.0011
Trypanosoma brucei pyruvate kinase 1, putative 0.0039 0.0144 0.0925
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.046 0.2947
Echinococcus granulosus pyruvate kinase 0.002 0.0059 0.0057
Schistosoma mansoni survival motor neuron protein 0.0056 0.0224 0.0224
Brugia malayi SET domain containing protein 0.0007 0.0001 0.0003
Brugia malayi Pyruvate kinase, M2 isozyme 0.0039 0.0144 0.0348
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0007 0.0002 0.0003
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0037 0.0036
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0005 0.0005
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0007 0.0002 0.001
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.0171 0.0169
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0119
Entamoeba histolytica hypothetical protein 0.0042 0.0159 0.0273
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.009
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0005 0.0003
Plasmodium falciparum steroid dehydrogenase, putative 0.0008 0.0005 0.0019
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0005 0.0016
Plasmodium falciparum glutathione reductase 0.0015 0.0038 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni intermediate filament proteins 0.0031 0.0111 0.0111
Brugia malayi pyruvate kinase 0.0008 0.0005 0.0013
Loa Loa (eye worm) sugar transporter 0.001 0.0013 0.0032
Leishmania major glucose transporter, lmgt3 0.001 0.0013 0.0086
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0027 0.0096
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0108 0.0185
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0138 0.0597 0.0595
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.01 0.0424 0.1515
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0532 0.2392 0.2392
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0005 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0005 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Onchocerca volvulus 0.0016 0.0041 0.0087
Echinococcus multilocularis Niemann Pick C1 protein 0.0114 0.049 0.0488
Echinococcus multilocularis protein patched 0.0049 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.015
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0094 0.0336
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.0005 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0571 0.2043
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0532 0.2392 0.4151
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0138 0.0597 0.2495
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0137 0.0592 0.0592
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0052 0.0125
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Leishmania major phosphopantetheinyl transferase-like protein 0.0074 0.0307 0.1966
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0572 0.0572
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0005 0.0029
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0138 0.0597 0.3818
Plasmodium falciparum glutathione reductase 0.0044 0.0168 0.0703
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0032 0.0115 0.0197
Plasmodium falciparum pyruvate kinase 0.0039 0.0144 0.0604
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0094 0.0226
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) RNA binding protein 0.0074 0.0304 0.0731
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Mycobacterium ulcerans sugar transporter 0.001 0.0013 0.0048
Onchocerca volvulus 0.001 0.0013 0.0028
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0007 0.0002 0.0005
Leishmania major short chain dehydrogenase, putative 0.0008 0.0005 0.0029
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Trypanosoma cruzi protein farnesyltransferase, putative 0.0032 0.0115 0.0735
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.001 0.0013 0.0086
Onchocerca volvulus 0.001 0.0013 0.0028
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0005 0.0003
Onchocerca volvulus 0.0057 0.023 0.0486
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Brugia malayi hypothetical protein 0.0017 0.0048 0.0116
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0108 0.2618
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0094 0.0336
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.01 0.0424 0.1515
Entamoeba histolytica hypothetical protein 0.0074 0.0307 0.0531
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.0261
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0144 0.0925
Brugia malayi hypothetical protein 0.0007 0.00000022915 0.00000055132
Toxoplasma gondii propionate-CoA ligase 0.0008 0.0005 0.003
Brugia malayi hypothetical protein 0.001 0.0013 0.0032
Leishmania major oxidoreductase-like protein 0.0008 0.0005 0.0029
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.007 0.0251
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0114 0.049 0.0848
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.028 0.028
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0532 0.2392 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Giardia lamblia Reductase, putative 0.0008 0.0005 0.0008
Brugia malayi hypothetical protein 0.001 0.0013 0.0032
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0005 0.0003
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0304 0.0731
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0486 0.1736
Echinococcus multilocularis pyruvate kinase 0.002 0.0059 0.0057
Brugia malayi Flap endonuclease-1 0.003 0.0106 0.0256
Schistosoma mansoni hypothetical protein 0.0197 0.0866 0.0866
Entamoeba histolytica Flap nuclease, putative 0.003 0.0106 0.0182
Loa Loa (eye worm) patched family protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0008 0.0005 0.0016
Onchocerca volvulus 0.0056 0.0224 0.0473
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus multilocularis L aminoadipate semialdehyde 0.0264 0.1173 0.1172
Entamoeba histolytica hypothetical protein 0.0042 0.0159 0.0273
Brugia malayi phosphofructokinase 0.0114 0.0486 0.1169
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Toxoplasma gondii patched family protein 0.0007 0.00000022915 0.0000012995
Onchocerca volvulus 0.003 0.0105 0.0222
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0027 0.0065
Onchocerca volvulus 0.0008 0.0005 0.001
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0032 0.0115 0.0276
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0005 0.0029
Leishmania major geranylgeranyltransferase, putative 0.0032 0.0115 0.0735
Echinococcus multilocularis geminin 0.0197 0.0866 0.0864
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Trypanosoma brucei unspecified product 0.0015 0.0039 0.0247
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0008 0.0005 0.0029
Brugia malayi Patched related family protein 4 0.0007 0.00000022915 0.00000055132
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0007 0.0002 0.001
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.001 0.0013 0.0048
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0106 0.068
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0486 0.1732
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0008 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0039 0.0144 0.0516
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0038 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0007 0.0002 0.0005
Schistosoma mansoni DNA helicase recq1 0.0009 0.001 0.001
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.007 0.0251
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0007 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0052
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0005 0.0029
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0005 0.0003
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0032 0.0115 0.0115
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0144 0.0305
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0074 0.0307 0.1098
Leishmania major dehydrogenase-like protein 0.0008 0.0005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Schistosoma mansoni pyruvate kinase 0.002 0.0059 0.0059
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0015 0.0035 0.0083
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.0841
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0007 0.0002 0.0006
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0008 0.0005 0.0003
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Echinococcus granulosus mixed lineage leukemia protein mll 0.0012 0.0024 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0094 0.0601
Onchocerca volvulus 0.001 0.0013 0.0028
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0486 0.3108
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0057 0.0204
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.007 0.0169
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0015 0.0038 0.0134
Giardia lamblia Prenyltransferase 0.0032 0.0115 0.0199
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.046 0.2947
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0486 0.0841
Echinococcus granulosus solute carrier family 22 0.001 0.0013 0.0012
Echinococcus multilocularis pyruvate kinase 0.0039 0.0144 0.0143
Brugia malayi hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma brucei glucose transporter, putative 0.001 0.0013 0.0086
Trypanosoma brucei glucose transporter 1E 0.001 0.0013 0.0086
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0008 0.0005 0.003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0062 0.0222
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0008 0.0005 0.0034
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.007 0.0119
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0007 0.0002 0.0009
Onchocerca volvulus 0.0008 0.0005 0.001
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0062 0.0222
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.001 0.0058
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.007 0.0119
Schistosoma mansoni DNA polymerase eta 0.0022 0.007 0.007
Onchocerca volvulus 0.0008 0.0005 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Onchocerca volvulus 0.001 0.0013 0.0028
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0192 0.0462
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0032 0.0115 0.048
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0023 0.0145
Trichomonas vaginalis glucose transporter, putative 0.001 0.0013 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0211 0.0209
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0008 0.0005 0.0003
Echinococcus granulosus cpg binding protein 0.0032 0.0113 0.0111
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0138 0.0597 0.2495
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0138 0.0597 0.0595
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans dehydrogenase 0.0008 0.0005 0.0016
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0015 0.0038 0.0157
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0108 0.0188
Plasmodium vivax pyruvate kinase 2, putative 0.002 0.0059 0.0246
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0008 0.0005 0.0016
Giardia lamblia Short-chain dehydrogenase, putative 0.0008 0.0005 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0005 0.0018
Giardia lamblia NADH oxidase lateral transfer candidate 0.0015 0.0038 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0005 0.0019
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0015 0.0038 0.024
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0008 0.0005 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0038 0.024
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0212 0.0932 0.0931
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0197
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0232 0.0559
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.0005 0.0005
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0008 0.0005 0.0029
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0037 0.0155
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0092 0.0384
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0008 0.0005 0.0003
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0032 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.2202 1 1
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Echinococcus granulosus lamin 0.0031 0.0111 0.011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.0002 0.001
Giardia lamblia DINP protein human, muc B family 0.0022 0.007 0.0122
Brugia malayi TAR-binding protein 0.0074 0.0304 0.0731
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0032
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Onchocerca volvulus 0.0028 0.0094 0.0198
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0106 0.0182
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.045
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0232 0.0559
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0007 0.0002 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0132 0.0572 0.1375
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0008 0.0005 0.0016
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0013
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.0002 0.001
Onchocerca volvulus 0.001 0.0013 0.0028
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0038 0.024
Leishmania major pyruvate kinase 0.0039 0.0144 0.0925
Schistosoma mansoni glucose transport protein 0.001 0.0013 0.0013
Leishmania major farnesyltransferase beta subunit 0.0032 0.0115 0.0735
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Echinococcus granulosus tar DNA binding protein 0.0074 0.0304 0.0302
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.001 0.0009
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0571 0.0571
Trypanosoma brucei oxidoreductase-like protein 0.0008 0.0005 0.0029
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.0005 0.0011
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0723 0.4626
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0007 0.0002 0.0006
Echinococcus granulosus tumor protein p63 0.0393 0.1758 0.1757
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0212 0.0932 0.2243
Brugia malayi beta-NAC-like protein 0.0078 0.0324 0.078
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0074 0.0307 0.1098
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0005 0.0029
Loa Loa (eye worm) histone methyltransferase 0.0014 0.0033 0.0079
Onchocerca volvulus 0.1046 0.4735 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.001 0.0009
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0111 0.0475 0.1692
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Trypanosoma brucei hypothetical protein, conserved 0.0138 0.0597 0.3818
Plasmodium vivax basic transcription factor 3b, putative 0.0078 0.0324 0.1355
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0394 0.1763 0.306
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0091 0.0219
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0005 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.046 0.046
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0013
Trypanosoma brucei pyruvate kinase 1 0.0039 0.0144 0.0925
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0506 0.1807
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0094 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0023 0.0145
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0108 0.0452
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0032 0.0115 0.0197
Echinococcus granulosus solute carrier family 22 0.001 0.0013 0.0012
Onchocerca volvulus 0.0008 0.0005 0.001
Schistosoma mansoni microtubule-associated protein tau 0.2202 1 1
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0007 0.0002 0.0004
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0005 0.0026
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0015 0.0038 0.0213
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0735
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0125
Leishmania major hypothetical protein, conserved 0.0027 0.0092 0.0588
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0008 0.0005 0.0026
Plasmodium vivax SET domain protein, putative 0.0132 0.0572 0.239
Leishmania major short chain dehydrogenase-like protein 0.0008 0.0005 0.0029
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0159 0.0157
Brugia malayi RNA binding protein 0.0074 0.0304 0.0731
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.0005 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Giardia lamblia Pyruvate kinase 0.002 0.0059 0.0102
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Echinococcus multilocularis flap endonuclease 1 0.003 0.0106 0.0105
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.001 0.0013 0.0056
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.0506 0.1807
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0092 0.0384
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Echinococcus multilocularis expressed conserved protein 0.0108 0.0458 0.0457
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0211 0.0507
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0304 0.0304
Echinococcus multilocularis protein dispatched 1 0.0056 0.0224 0.0222
Echinococcus multilocularis bloom syndrome protein 0.0022 0.007 0.0068
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.045
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0532 0.2392 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0039 0.0247
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0013 0.0021
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0007 0.0002 0.0004
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0032 0.0115 0.0113
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0307 0.1093
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0027 0.0172
Onchocerca volvulus Putative transporter 0.001 0.0013 0.0028
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0052 0.005
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0138 0.0597 0.3818
Echinococcus multilocularis musashi 0.0031 0.0111 0.011
Trypanosoma cruzi hexose transporter, putative 0.001 0.0013 0.0086
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0008 0.0005 0.0097
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0008 0.0005 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0013
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0005 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.007 0.0251
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.0002 0.001
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi pyruvate kinase, muscle isozyme 0.0008 0.0005 0.0013
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0033 0.0031
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0008 0.0005 0.0006
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0005 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0008 0.0005 0.0016
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0005 0.0004
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.007 0.0119
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0486 0.0484
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0212 0.0932 0.1616
Onchocerca volvulus 0.001 0.0013 0.0028
Echinococcus granulosus hypothetical protein 0.0008 0.0005 0.0003
Onchocerca volvulus 0.0264 0.1173 0.2478
Brugia malayi 6-phosphofructokinase 0.0114 0.0486 0.1169
Echinococcus multilocularis solute carrier family 22 0.001 0.0013 0.0012
Entamoeba histolytica hypothetical protein 0.0042 0.0159 0.0273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0007 0.0002 0.0006
Brugia malayi Patched protein homolog 1 0.0007 0.00000022915 0.00000055132
Mycobacterium ulcerans integral membrane transport protein 0.001 0.0013 0.0048
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0108 0.0452
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0005 0.0029
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0032 0.0115 0.0197
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1271 0.576 1
Onchocerca volvulus 0.001 0.0013 0.0028
Plasmodium vivax glutathione reductase, putative 0.0044 0.0168 0.0703
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0138 0.0597 0.3818
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0138 0.0597 0.3818
Trypanosoma brucei mitochondrial DNA polymerase beta 0.035 0.1563 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0005 0.0005
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.0571 0.057
Loa Loa (eye worm) patched family protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) hypothetical protein 0.004 0.0149 0.0358
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0138 0.0597 0.3818
Onchocerca volvulus 0.0008 0.0005 0.001
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0486 0.0486
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Trypanosoma brucei protein kinase, putative 0.0108 0.046 0.2947
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0486 0.0841
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.015
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0007 0.0002 0.0002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.046 0.2611
Plasmodium vivax acetyl-CoA synthetase, putative 0.0008 0.0005 0.0022
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0168 0.1076
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0008 0.0005 0.0029
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0007 0.0002 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0011
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0015 0.0038 0.0036
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0005 0.0005
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0074 0.0307 0.1742
Mycobacterium ulcerans dehydrogenase/reductase 0.0008 0.0005 0.0016
Leishmania major short chain dehydrogenase, putative 0.0008 0.0005 0.0029
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Giardia lamblia Alcohol dehydrogenase 0.0007 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0132 0.0572 0.0572
Schistosoma mansoni hypothetical protein 0.004 0.0149 0.0149
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi Sugar transporter family protein 0.001 0.0013 0.0032
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0052 0.005
Brugia malayi Cytochrome P450 family protein 0.0013 0.0027 0.0065
Loa Loa (eye worm) patched family protein 0.0007 0.00000022915 0.00000055132
Trichomonas vaginalis set domain proteins, putative 0.1046 0.4735 0.8219
Trypanosoma cruzi transcription factor btf3, putative 0.0078 0.0324 0.2074
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0007 0.0002 0.0006
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0007 0.00000022915 0.00000055132
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0005 0.0016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Toxoplasma gondii facilitative glucose transporter GT1 0.001 0.0013 0.0076
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0005 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0166 0.0723 0.4626
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0013 0.0012
Onchocerca volvulus 0.0008 0.0005 0.001
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0532 0.2392 0.5754
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0108 0.0452
Onchocerca volvulus 0.001 0.0013 0.0028
Onchocerca volvulus 0.0008 0.0005 0.0011
Leishmania major hypothetical protein, conserved 0.0009 0.0012 0.0074
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0007 0.0002 0.0006
Brugia malayi protein C24B5.3 0.0007 0.00000022915 0.00000055132
Trichomonas vaginalis sugar transporter, putative 0.001 0.0013 0.0021
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0264 0.1173 0.2822
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0057 0.0204
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0005 0.0029
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0094 0.0226
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0005 0.0018
Echinococcus multilocularis pyruvate kinase 0.002 0.0059 0.0057
Trichomonas vaginalis mercuric reductase, putative 0.0015 0.0038 0.0063
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0005 0.0016
Brugia malayi 6-phosphofructokinase 0.0114 0.0486 0.1169
Toxoplasma gondii transporter, major facilitator family protein 0.001 0.0013 0.0076
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.01 0.0424 0.1515
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0026
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0005 0.0029
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0007 0.0002 0.0006
Echinococcus granulosus lamin dm0 0.0031 0.0111 0.011
Toxoplasma gondii hypothetical protein 0.0138 0.0597 0.3383
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.0005 0.0005
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0007 0.0002 0.001
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Brugia malayi Sugar transporter family protein 0.001 0.0013 0.0032
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0106 0.0445
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1271 0.576 1
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.001 0.0013 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0057 0.0204
Giardia lamblia Fructose-bisphosphate aldolase 0.1271 0.576 1
Onchocerca volvulus 0.001 0.0013 0.0028
Echinococcus granulosus intermediate filament protein 0.0031 0.0111 0.011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0024 0.0023
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0532 0.2392 0.4151
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0221
Schistosoma mansoni glucose transport protein 0.001 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0011
Treponema pallidum NADH oxidase 0.0015 0.0038 0.0063
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0212 0.0932 0.0932
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0032 0.0115 0.0735
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0572 0.0572
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0137 0.0592 0.1425
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0212 0.0932 0.0932
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0052 0.005
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.0002 0.001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0024 0.0022
Echinococcus granulosus geminin 0.0197 0.0866 0.0864
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0192 0.0191
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0005 0.0029
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0672 0.3029 0.5257
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0007 0.0002 0.001
Onchocerca volvulus Sepiapterin reductase homolog 0.0008 0.0005 0.001
Brugia malayi Patched family protein 0.0007 0.00000022915 0.00000055132
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0144 0.0348
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0032 0.0115 0.041
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0029
Echinococcus multilocularis pyruvate kinase 0.0031 0.0107 0.0106
Echinococcus granulosus dna polymerase eta 0.0022 0.007 0.0069
Toxoplasma gondii patched family protein 0.0007 0.00000022915 0.0000012995

Activities

Activity type Activity value Assay description Source Reference
Log CDGH (functional) = 1.477 Increased production of growth hormone ChEMBL. 15686952
Log CDQR (functional) = 0.699 Increased quinone reductase specific activity ChEMBL. 15686952
Log CDQR (functional) = 0.699 Increased quinone reductase specific activity ChEMBL. 15686952
logP (ADMET) = 3.25 Partition coefficient (logP) ChEMBL. 15686952

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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