Detailed information for compound 427968

Basic information

Technical information
  • TDR Targets ID: 427968
  • Name: N-[4-[6-[4-[1-(4-fluorophenyl)ethyl]piperazin -1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-y l]acetamide
  • MW: 492.568 | Formula: C25H25FN6O2S
  • H donors: 1 H acceptors: 4 LogP: 4.3 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1sc2c(n1)c(ccc2)Oc1ncnc(c1)N1CCN(CC1)C(c1ccc(cc1)F)C
  • InChi: 1S/C25H25FN6O2S/c1-16(18-6-8-19(26)9-7-18)31-10-12-32(13-11-31)22-14-23(28-15-27-22)34-20-4-3-5-21-24(20)30-25(35-21)29-17(2)33/h3-9,14-16H,10-13H2,1-2H3,(H,29,30,33)
  • InChiKey: QUHZTEMPQQZPNB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[[6-[4-[1-(4-fluorophenyl)ethyl]-1-piperazinyl]-4-pyrimidinyl]oxy]-1,3-benzothiazol-2-yl]acetamide
  • N-[4-[6-[4-[1-(4-fluorophenyl)ethyl]piperazin-1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]ethanamide
  • N-[4-[6-[4-[1-(4-fluorophenyl)ethyl]piperazino]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Vanilloid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Onchocerca volvulus Glycogen phosphorylase homolog 0.0116 0.028 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0367
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0017 0.0032
Brugia malayi acetyltransferase, GNAT family protein 0.0173 0.0431 0.0846
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0758 0.1988 0.3905
Onchocerca volvulus 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0037
Loa Loa (eye worm) MBCTL1 0.0053 0.0111 0.0219
Brugia malayi Cathepsin L-like precursor 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0044
Schistosoma mansoni thyroid hormone receptor 0.003 0.005 0.0085
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.0646
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0111 0.0111
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Trypanosoma brucei C-8 sterol isomerase, putative 0.0758 0.1988 1
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0014 0.0161
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0111 0.0111
Plasmodium vivax vivapain-2 0.002 0.0024 0.028
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0014 0.0161
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0111 0.0111
Schistosoma mansoni myosin xvIII 0.0131 0.032 0.0542
Entamoeba histolytica protein kinase, putative 0.0057 0.0123 0.3335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Entamoeba histolytica glycogen phosphorylase, putative 0.0116 0.028 0.7597
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0829
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.005 0.0099
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0016 0.0013 0.0013
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0281 0.0281
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0021
Onchocerca volvulus 0.002 0.0024 0.0046
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.005 0.0098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0017 0.0465
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus metabotropic glutamate receptor 2 0.0016 0.0013 0.0013
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.005 0.0085
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0015 0.0175
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0326 0.084 0.084
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0017 0.0032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0131 0.032 0.0628
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0288 0.0567
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0029
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0046 0.009
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi hypothetical protein 0.0035 0.0064 0.0125
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Brugia malayi vesicular acetylcholine transporter unc-17 0.1122 0.2957 0.5808
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0008 0.0013
Echinococcus multilocularis synaptojanin 1 0.0016 0.0014 0.0014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0094 0.0184
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Entamoeba histolytica hypothetical protein 0.0028 0.0046 0.1239
Brugia malayi diacylglycerol kinase 0.0017 0.0015 0.0029
Onchocerca volvulus 0.0131 0.032 0.0628
Onchocerca volvulus 0.0028 0.0046 0.009
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0031 0.0031
Trypanosoma cruzi extracellular receptor, putative 0.0016 0.0013 0.005
Brugia malayi Cation transporter family protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) TK protein kinase 0.0042 0.0081 0.0159
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0281 0.0527
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Echinococcus granulosus glutamate NMDA receptor subunit 0.0325 0.0835 0.0835
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0077 0.1289
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0018 0.0087
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0014 0.0023
Loa Loa (eye worm) glutamate receptor 0.0016 0.0013 0.0025
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0065 0.0779
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0013
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0131 0.032 0.032
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0131 0.032 0.032
Echinococcus multilocularis serotonin receptor 0.0131 0.032 0.032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Brugia malayi PAS domain containing protein 0.0051 0.0107 0.021
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0131 0.032 0.0542
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0008 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.032 0.032
Onchocerca volvulus 0.0127 0.0309 0.0607
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0034
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0281 1
Brugia malayi carbohydrate phosphorylase 0.0116 0.028 0.055
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Tachykinin-like peptides receptor 99D 0.0131 0.032 0.0628
Onchocerca volvulus 0.0037 0.0068 0.0133
Onchocerca volvulus 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis sodium and chloride dependent glycine 0.0326 0.084 0.084
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.005 0.0085
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0088
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0043 0.0201
Leishmania major C-14 sterol reductase, putative 0.0092 0.0216 0.1082
Onchocerca volvulus Cathepsin L homolog 0.002 0.0024 0.0046
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0055 0.0649
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Onchocerca volvulus 0.0024 0.0035 0.0068
Echinococcus granulosus protein kinase c eta type 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0129
Leishmania major DNA polymerase kappa, putative 0.0025 0.0038 0.0187
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0012 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0131 0.032 0.032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0274 0.07 0.1376
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.032 0.032
Echinococcus granulosus FTZ F1 alpha 0.003 0.005 0.005
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0142 0.0142
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0281 1
Brugia malayi Protein kinase c protein 2 0.0017 0.0017 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0077 0.1289
Loa Loa (eye worm) RNA binding protein 0.0066 0.0146 0.0286
Onchocerca volvulus 0.0016 0.0013 0.0024
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0017 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) glutamate receptor 2 0.0153 0.0377 0.0741
Toxoplasma gondii diacylglycerol kinase, putative 0.0017 0.0015 0.0182
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0077 0.0915
Schistosoma mansoni nocturnin 0.0016 0.0014 0.0023
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0018 0.003
Loa Loa (eye worm) inositol-1 0.0074 0.0167 0.0328
Echinococcus multilocularis muscleblind protein 0.0145 0.0358 0.0358
Schistosoma mansoni glutamate receptor NMDA 0.025 0.0637 0.108
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0017 0.0017 0.0033
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0131 0.032 0.0542
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0046 0.009
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0068 0.0068
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis tyrosine protein kinase HCK 0.0037 0.007 0.007
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0111 0.0217
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0077 0.0406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0062 0.0062
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0035 0.0176
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Brugia malayi Metabotropic glutamate receptor precursor. 0.0016 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0038 0.0072 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0326 0.084 0.1423
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0323 0.0829 0.0829
Echinococcus granulosus dro:myosuppressin receptor 0.0131 0.032 0.032
Schistosoma mansoni unc-13 (munc13) 0.0019 0.0021 0.0035
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.005 0.0105 0.1703
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Brugia malayi Raf kinase 0.0466 0.1211 0.2378
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni neuropeptide f receptor 76f 0.0131 0.032 0.0542
Schistosoma mansoni inositol monophosphatase 0.0074 0.0167 0.0283
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0101 0.154
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0012 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0024 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0094 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0006 0.0085
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0057 0.0121 0.0121
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0111 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0111 0.0217
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0014 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Echinococcus granulosus g-protein coupled receptor 0.0131 0.032 0.032
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0107 0.0181
Brugia malayi nuclear receptor NHR-88 0.003 0.005 0.0098
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.005 0.005
Brugia malayi Uncoordinated protein 44 0.0015 0.0012 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Onchocerca volvulus 0.0131 0.032 0.0628
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0014 0.0161
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000046697 0.0000091722
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0131 0.032 0.0542
Schistosoma mansoni biogenic amine (5HT) receptor 0.0131 0.032 0.0542
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0184 0.0184
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0068 0.0943
Brugia malayi nuclear hormone receptor 0.003 0.005 0.0098
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0131 0.032 0.0628
Brugia malayi Pleckstrin Homology Domain 0.0017 0.0015 0.0029
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0003 0.0003
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0013 0.0024
Schistosoma mansoni nuclear hormone receptor 0.003 0.005 0.0085
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0077 0.1289
Brugia malayi hypothetical protein 0.0064 0.0142 0.0278
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0014 0.0069
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Onchocerca volvulus 0.0127 0.0309 0.0607
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus multilocularis c src tyrosine kinase 0.0012 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0131 0.032 0.0628
Schistosoma mansoni biogenic amine (5HT) receptor 0.0131 0.032 0.0542
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0077 0.1289
Schistosoma mansoni diacylglycerol kinase theta 0.0017 0.0015 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Onchocerca volvulus 0.002 0.0024 0.0046
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0184 0.0361
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Echinococcus granulosus sodium and chloride dependent glycine 0.0326 0.084 0.084
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3767 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0023
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.015 0.0369 0.0725
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0111 0.0217
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Echinococcus granulosus metabotropic glutamate receptor 5 0.0016 0.0013 0.0013
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0008 0.0008
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0046 0.0077
Leishmania major sterol C-24 reductase, putative 0.0048 0.0098 0.0491
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0184 0.0184
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0077 0.1289
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0011 0.002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0167 0.2312
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0065 0.0065
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0106 0.1259
Onchocerca volvulus 0.0131 0.032 0.0628
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0077 0.1289
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0012 0.0002 0.0002
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0019 0.0022 0.0037
Brugia malayi nuclear receptor RXR 0.0014 0.0008 0.0015
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0046 0.0077
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0015 0.0025
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0111 0.0188
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0006 0.001
Onchocerca volvulus 0.002 0.0024 0.0046
Schistosoma mansoni diacylglycerol kinase theta 0.0017 0.0015 0.0025
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0325 0.0835 0.0835
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Echinococcus granulosus intermediate filament protein 0.0028 0.0045 0.0045
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0017 0.0465
Schistosoma mansoni growth hormone secretagogue receptor 0.0131 0.032 0.0542
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Brugia malayi hypothetical protein 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0064 0.0142 0.0279
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1122 0.2957 0.5809
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0012 0.0012
Onchocerca volvulus 0.0131 0.032 0.0628
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Echinococcus granulosus transcription factor Dp 1 0.0087 0.0201 0.0201
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Echinococcus granulosus protein kinase c iota type 0.0017 0.0017 0.0017
Brugia malayi Cytochrome P450 family protein 0.0078 0.0178 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.1923 0.5091 0.8629
Echinococcus multilocularis glutamate receptor NMDA 0.0082 0.0188 0.0188
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0014 0.0056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.032 0.0542
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.005 0.005
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0077 0.0406
Echinococcus granulosus Rac GTPase activating protein 1 0.0017 0.0015 0.0015
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0035 0.0163
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0008 0.0013
Schistosoma mansoni nuclear receptor 0.0014 0.0008 0.0013
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Brugia malayi 6-phosphofructokinase 0.0117 0.0281 0.0552
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Brugia malayi G protein-coupled receptor 0.0131 0.032 0.0628
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0043 0.0214
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0014 0.0191
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.0646
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0131 0.032 0.0628
Echinococcus multilocularis N chimaerin 0.0021 0.0027 0.0027
Echinococcus granulosus nAChR subunit 0.0028 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus granulosus serotonin transporter 0.1923 0.5091 0.5091
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0098 0.0479
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0017 0.0075
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0043 0.0507
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0646
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0035 0.0035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.0123 0.1464
Onchocerca volvulus 0.0013 0.0006 0.0011
Echinococcus granulosus lamin dm0 0.0028 0.0045 0.0045
Brugia malayi Dopamine receptor protein 1 0.0131 0.032 0.0628
Schistosoma mansoni hypothetical protein 0.0703 0.1842 0.3121
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0014 0.0027
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0077 0.2574
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0036
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0077 0.0406
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0216 0.1072
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.005 0.0099
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0055 0.1526
Brugia malayi Pre-SET motif family protein 0.0036 0.0065 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0131 0.032 0.032
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0377 0.0639
Brugia malayi steroid hormone receptor 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0014 0.0227
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Echinococcus multilocularis G-protein coupled receptor, putative 0.0131 0.032 0.032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0038 0.0189
Schistosoma mansoni protein kinase C mu 0.0017 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Brugia malayi RhoGEF domain containing protein 0.0017 0.0015 0.0029
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0094 0.0094
Loa Loa (eye worm) RasGEF domain-containing protein 0.0017 0.0015 0.003
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0281 0.1413
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0077 0.1289
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0057 0.0121 0.0121
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0125 0.0629
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0068 0.1143
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0086
Brugia malayi Steroid receptor seven-up type 2 0.003 0.005 0.0098
Leishmania major cysteine peptidase A (CPA) 0.002 0.0024 0.0118
Echinococcus granulosus Ankyrin 0.0016 0.0013 0.0013
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0161
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0077 0.1289
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0077 0.1289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi RhoGAP domain containing protein 0.0021 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Onchocerca volvulus 0.0326 0.084 0.1649
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0037 0.0069 0.0136
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.065 0.1276
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0111 0.0111
Echinococcus granulosus Diacylglycerol kinase theta 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Echinococcus multilocularis fmrfamide receptor 0.0131 0.032 0.032
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0038 0.0626
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0111 0.0217
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.044 0.6089
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0131 0.032 0.032
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Echinococcus granulosus glycogen phosphorylase 0.0116 0.028 0.028
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0014 0.0367
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0127 0.0309 0.0524
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.005 0.0098
Loa Loa (eye worm) fibroinase 0.002 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Entamoeba histolytica glycogenphosphorylase, putative 0.005 0.0105 0.2827
Loa Loa (eye worm) SRC-1 0.0046 0.0092 0.0182
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0015 0.0025
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Brugia malayi cathepsin L-like precursor 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0013 0.0006 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0014 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Giardia lamblia GTOR 0.0018 0.0017 0.0136
Loa Loa (eye worm) hypothetical protein 0.0103 0.0245 0.0481
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0281 0.0476
Toxoplasma gondii cathepsin CPL 0.002 0.0024 0.0283
Brugia malayi sulfakinin receptor protein 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0068 0.033
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0003 0.0064
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.065 0.1277
Trichomonas vaginalis glycogen phosphorylase, putative 0.0116 0.028 0.3877
Schistosoma mansoni vesicular amine transporter 0.0567 0.1479 0.2506
Schistosoma mansoni sodium/chloride dependent transporter 0.0326 0.084 0.1423
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0181 0.0181
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0065 0.0065
Echinococcus granulosus dna polymerase eta 0.0017 0.0017 0.0017
Trichomonas vaginalis esterase, putative 0.0037 0.0068 0.0943
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0111 0.0111
Echinococcus granulosus protein kinase shaggy 0.0057 0.0123 0.0123
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0131 0.032 0.032
Onchocerca volvulus 0.0057 0.0123 0.0241
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0131 0.032 0.0629
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Echinococcus multilocularis Glycosyl transferase, family 35 0.0116 0.028 0.028
Brugia malayi Cation transporter family protein 0.0127 0.0309 0.0607
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0088
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.005 0.0099
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0013 0.0021
Echinococcus multilocularis protein kinase c eta type 0.0017 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.1013 0.2668 0.5241
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0074
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0015 0.0075
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0125 0.0246
Schistosoma mansoni hypothetical protein 0.004 0.0077 0.013
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0014 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0077 0.0374
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0013 0.0021
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0057 0.0121 0.0121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Echinococcus multilocularis serotonin transporter 0.1923 0.5091 0.5091
Brugia malayi RE15519p 0.0131 0.032 0.0628
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Echinococcus multilocularis somatostatin receptor 0.0131 0.032 0.032
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0017 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0017 0.0029
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0085 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0034
Brugia malayi Dopamine receptor 0.0131 0.032 0.0628
Brugia malayi polk-prov protein 0.0037 0.0069 0.0136
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.015 0.0369 0.0369
Echinococcus multilocularis Rac GTPase activating protein 1 0.0017 0.0015 0.0015
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.1255 0.2127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.005 0.005
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0094 0.0159
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.008 0.0185 0.5004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0065 0.0065
Echinococcus multilocularis synaptic vesicular amine transporter 0.0567 0.1479 0.1479
Echinococcus multilocularis allatostatin A receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus nmda type glutamate receptor 0.0138 0.0339 0.0339
Echinococcus granulosus myotubularin protein 13 0.0017 0.0015 0.0015
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0111 0.0111
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0179
Echinococcus multilocularis lamin dm0 0.0028 0.0045 0.0045
Loa Loa (eye worm) acetyltransferase 0.0173 0.0431 0.0847
Echinococcus multilocularis neuropeptide s receptor 0.0131 0.032 0.032
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0035 0.0068
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0008 0.0015
Echinococcus multilocularis sex peptide receptor 0.0131 0.032 0.032
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0008 0.0008
Schistosoma mansoni atypical protein kinase C 0.0017 0.0017 0.0028
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0077 0.0374
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.013 0.0641
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Schistosoma mansoni cytochrome P450 0.004 0.0077 0.013
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0501 0.0501
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0012 0.0022
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0131 0.032 0.0628
Schistosoma mansoni glycogen phosphorylase 0.0116 0.028 0.0475
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0131 0.032 0.0629
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0013 0.0025
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0014 0.0068
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0646
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0127 0.0309 0.0524
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Onchocerca volvulus 0.002 0.0024 0.0046
Echinococcus granulosus G protein coupled receptor 139 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Giardia lamblia DINP protein human, muc B family 0.0025 0.0038 0.0889
Onchocerca volvulus 0.0028 0.0045 0.0088
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.032 0.0542
Echinococcus granulosus serotonin receptor 0.0131 0.032 0.032
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.0022 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.032 0.032
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.005 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.032 0.032
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0017 0.0088
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0006 0.0083
Leishmania major cytochrome p450-like protein 0.004 0.0077 0.0385
Schistosoma mansoni vav2 0.0021 0.0027 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0014 0.0161
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0123 0.3335
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Loa Loa (eye worm) melatonin receptor type 1A 0.0131 0.032 0.0629
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1122 0.2957 0.5808
Echinococcus granulosus raf serine:threonine protein kinase 0.0483 0.1255 0.1255
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0014 0.0191
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Brugia malayi beta-lactamase 0.0037 0.0068 0.0133
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.005 0.0085
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0125 0.0617
Brugia malayi RhoGAP domain containing protein 0.0017 0.0015 0.0029
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0367
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0167 0.4646
Loa Loa (eye worm) hypothetical protein 0.0145 0.0358 0.0703
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0406
Echinococcus granulosus atrial natriuretic peptide receptor 0.0016 0.0013 0.0013
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0123 0.1704
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0077 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Schistosoma mansoni tyrosine kinase 0.0019 0.0022 0.0037
Brugia malayi AKH receptor 0.0131 0.032 0.0628
Brugia malayi isocitrate dehydrogenase 0.0017 0.0015 0.0029
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0081 0.0081
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0106 0.1465
Brugia malayi Cytochrome P450 family protein 0.0058 0.0125 0.0245
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0085 0.0167
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Echinococcus multilocularis unc 13 (munc13) 0.0017 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0077 0.1289
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0035 0.0416
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0027 0.0045
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Entamoeba histolytica cysteine protease, putative 0.002 0.0024 0.0637
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0068 0.033
Schistosoma mansoni inositol monophosphatase 0.0074 0.0167 0.0283
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0016 0.0013 0.0025
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0055 0.008
Echinococcus granulosus glycogen phosphorylase 0.0116 0.028 0.028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0013 0.0021
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.005 0.0098
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0011 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0131 0.032 0.032
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0092 0.0092
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.005 0.005
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Schistosoma mansoni vesicular acetylcholine transporter 0.1122 0.2957 0.5012
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.005 0.0098
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0101 0.0508
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0045 0.0089
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0077 0.0387
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Onchocerca volvulus 0.0131 0.032 0.0628
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0017 0.007
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0012 0.0003 0.0003
Echinococcus multilocularis cysteine protease 0.002 0.0024 0.0024
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0169 0.0419 0.0419
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0027 0.0052
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0016 0.0013 0.0013
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0014 0.0023
Brugia malayi Inositol-1 0.0074 0.0167 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.005 0.0099
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0011 0.0011
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0 0.0004
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0095 0.1124
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0105 0.2827
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.005 0.0098
Echinococcus multilocularis dna polymerase kappa 0.0049 0.0101 0.0101
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Leishmania major cytochrome p450-like protein 0.0058 0.0125 0.0628
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0035 0.0059
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0017 0.0028
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Schistosoma mansoni hypothetical protein 0.0057 0.0121 0.0205
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.0111 0.0111
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Plasmodium vivax vivapain-2 0.002 0.0024 0.028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Loa Loa (eye worm) TYRA-2 protein 0.0131 0.032 0.0629
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0015 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Echinococcus granulosus glutamate receptor subunit protein glur 0.0057 0.0121 0.0121
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0006 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0167 0.4527
Loa Loa (eye worm) RecQ helicase 0.0023 0.0031 0.006
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0167 0.0167
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0024 0.0024
Echinococcus granulosus tar DNA binding protein 0.0066 0.0146 0.0146
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.015 0.0369 0.0724
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0024 0.0046
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0111 0.0217
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0185 0.2555
Echinococcus multilocularis myotubularin protein 13 0.0017 0.0015 0.0015
Brugia malayi G protein-coupled receptor F59B2.13 0.0131 0.032 0.0628
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0092 0.0092
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0131 0.032 0.032
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0646 0.1268
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0012 0.0003 0.0003
Echinococcus multilocularis RUN 0.0064 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.005 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0111 0.0111
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0013
Brugia malayi Melatonin receptor type 1A 0.0131 0.032 0.0628
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0185 0.2197
Brugia malayi protein kinase C3,putative 0.0017 0.0017 0.0032
Echinococcus granulosus neuropeptide receptor A26 0.0131 0.032 0.032
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0147 0.5107
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.0123 0.0208
Treponema pallidum exodeoxyribonuclease (exoA) 0.008 0.0185 0.0337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Brugia malayi phosphofructokinase 0.0117 0.0281 0.0552
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.005 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0024
Echinococcus granulosus tyrosine kinase 0.0042 0.0081 0.0081
Trichomonas vaginalis DNA polymerase eta, putative 0.0049 0.0101 0.1397
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0014 0.0056
Echinococcus multilocularis GPCR, family 2 0.008 0.0184 0.0184
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0011 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2072 0.2072
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis Ankyrin 0.0016 0.0013 0.0013
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0077 0.0385
Onchocerca volvulus 0.0037 0.0068 0.0133
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0156
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0077 0.1289
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0173 0.0859
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica hypothetical protein 0.0016 0.0013 0.0335
Echinococcus granulosus neuropeptide receptor 0.0131 0.032 0.032
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0006 0.0069
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0281 0.0476
Echinococcus granulosus synaptic vesicular amine transporter 0.0567 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0092 0.0092
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0017 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Echinococcus granulosus sex peptide receptor 0.0131 0.032 0.032
Echinococcus multilocularis tyrosine kinase 0.0019 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0077 0.1289
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0077 0.0406
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.032 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0123 0.1704
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0123 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Brugia malayi neuropeptide F receptor 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0011 0.0011
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0123 0.0242
Echinococcus granulosus peptide allatostatin:somatostatin 0.0131 0.032 0.032
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0111 0.0218
Schistosoma mansoni nuclear receptor 0.0014 0.0008 0.0013
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Schistosoma mansoni thyroid hormone receptor 0.003 0.005 0.0085
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.005 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus granulosus histone acetyltransferase KAT2B 0.0168 0.0418 0.0418
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Chlamydia trachomatis glycogen phosphorylase 0.0116 0.028 0.3336
Brugia malayi mbt repeat family protein 0.0046 0.0094 0.0184
Loa Loa (eye worm) serotonin transporter b 0.1923 0.5091 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0017 0.0029
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0021 0.0027 0.0027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0008 0.0008
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0101 0.154
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0035 0.0068
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0017 0.0441
Echinococcus granulosus alpha 1A adrenergic receptor 0.0131 0.032 0.032
Schistosoma mansoni ap endonuclease 0.008 0.0185 0.0313
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0069 0.0349
Schistosoma mansoni glutamate receptor NMDA 0.0325 0.0835 0.1414
Brugia malayi intermediate filament protein 0.0028 0.0045 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.005 0.0085
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0281 0.0281
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Brugia malayi 6-phosphofructokinase 0.0117 0.0282 0.0552
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.0123 0.0618
Onchocerca volvulus 0.0014 0.0008 0.0015
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0387 0.1002 0.1968
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0008 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0014 0.0068
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Brugia malayi Cytochrome P450 family protein 0.0058 0.0125 0.0245
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0012 0.0012
Echinococcus granulosus orexin receptor type 2 0.0131 0.032 0.032
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Schistosoma mansoni microtubule-associated protein tau 0.2227 0.59 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0017
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.0022 0.0022
Brugia malayi Cytochrome P450 family protein 0.004 0.0077 0.015
Brugia malayi Dopamine receptor protein 2 0.0131 0.032 0.0628
Schistosoma mansoni lipoxygenase 0.0207 0.0521 0.0882
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.008 0.0185 0.0917
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0111 0.0187
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0127 0.0309 0.0607
Echinococcus granulosus glutamate receptor NMDA 0.0082 0.0188 0.0188
Echinococcus multilocularis raf serine:threonine protein kinase 0.0483 0.1255 0.1255
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0057 0.0121 0.0121
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.015 0.0369 0.0369
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0646 0.1268
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0035 0.0068
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0185
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0022
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0006 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0077 0.1289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0019
Trypanosoma brucei C-14 sterol reductase, putative 0.0092 0.0216 0.1084
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0046 0.009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0086
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0077 0.0406
Echinococcus multilocularis 0.004 0.0077 0.0077
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0131 0.032 0.032
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0014 0.0056
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Onchocerca volvulus Putative nachr subunit 0.0053 0.0111 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0281 0.0552
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0123 0.3335
Toxoplasma gondii exonuclease III APE 0.008 0.0185 0.22
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0012 0.0012
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0068 0.0933
Onchocerca volvulus 0.0127 0.0309 0.0607
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Brugia malayi C1-like domain containing protein 0.0017 0.0017 0.0032
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0131 0.032 0.0542
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0014 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0024 0.004
Echinococcus granulosus cathepsin l1 0.0013 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0077 0.0406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0089
Echinococcus granulosus hypothetical protein 0.0131 0.032 0.032
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0092 0.0092
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0167 0.0167
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0018 0.0075
Plasmodium falciparum transporter, putative 0.0326 0.084 1
Onchocerca volvulus 0.002 0.0024 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0077 0.1289
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0094 0.0159
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0111 0.0217
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.005 0.0085
Echinococcus multilocularis protein kinase c iota type 0.0017 0.0017 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0098 0.0192
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0068 0.1143
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.032 0.032
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0068 0.0943
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0095 0.3034
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0013 0.0021
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0064 0.0064
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0378 0.0978 0.192
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0014 0.0056
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0014 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0281 0.1403
Echinococcus multilocularis nAChR subunit 0.0053 0.0111 0.0111
Onchocerca volvulus 0.0037 0.0068 0.0133
Brugia malayi protein kinase C II. 0.0017 0.0017 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0068 0.0809
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0077 0.0406
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.005 0.0098
Brugia malayi Latrophilin receptor protein 2 0.008 0.0184 0.0361
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Onchocerca volvulus 0.0053 0.0111 0.0217
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.0111 0.0111
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Schistosoma mansoni nAChR subunit 0.0024 0.0035 0.0059
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0377 0.0639
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0105 0.2827
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0501 0.0501
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0567 0.1479 0.2905
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Entamoeba histolytica glycogen phosphorylase, putative 0.0116 0.028 0.7597
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Loa Loa (eye worm) steroid hormone receptor 0.003 0.005 0.0099
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0125 0.0246
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0077 0.0406
Echinococcus multilocularis nAChR subunit 0.0028 0.0046 0.0046
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Onchocerca volvulus 0.0028 0.0045 0.0088
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.005 0.005
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0179
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.005 0.005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1845
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0017 0.0017 0.0032
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0031 0.0423
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0131 0.032 0.032
Onchocerca volvulus 0.0053 0.0111 0.0217
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0 0.0001
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0014 0.0014
Schistosoma mansoni lamin 0.0028 0.0045 0.0076
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0006 0.0012
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0068 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.005 0.0098
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0017 0.0086
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0068 0.0343
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0035 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0172 0.0429 0.0842
Onchocerca volvulus 0.1923 0.5091 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0047
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis sodium and chloride dependent glycine 0.0326 0.084 0.084
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0345 0.0676
Echinococcus multilocularis lamin 0.0028 0.0045 0.0045
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0014 0.0056
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Schistosoma mansoni Lamin B receptor (ERG24) 0.0092 0.0216 0.0365
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0014 0.0014
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0057 0.0121 0.0121
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.015 0.0369 0.1854
Toxoplasma gondii hypothetical protein 0.0326 0.084 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0008 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0011 0.0011
Toxoplasma gondii hypothetical protein 0.0326 0.084 1
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.005 0.005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0011 0.0127
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0011 0.0129
Brugia malayi TAR-binding protein 0.0066 0.0146 0.0285
Leishmania major protein kinase, putative 0.0019 0.0021 0.0105
Plasmodium falciparum amino acid transporter, putative 0.0326 0.084 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi nuclear receptor NHR-67 0.0014 0.0008 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Brugia malayi nuclear receptor RXR 0.0016 0.0013 0.0024
Schistosoma mansoni zinc finger protein 0.0014 0.0008 0.0013
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.008 0.0185 0.0185
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0026 0.0117
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0015 0.003
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0077 0.1289
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Entamoeba histolytica diacylglycerol kinase, putative 0.0017 0.0015 0.0406
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0123 0.4105
Onchocerca volvulus 0.0016 0.0014 0.0027
Echinococcus multilocularis microtubule associated protein 2 0.2227 0.59 0.59
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0288 0.0567
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Leishmania major hypothetical protein, conserved 0.0027 0.0043 0.0213
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1845
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi hypothetical protein 0.0027 0.0043 0.0083
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0185 0.2555
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0077 0.0406
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0234 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni hypothetical protein 0.0173 0.0432 0.0732
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0072 0.0159
Echinococcus granulosus bloom syndrome protein 0.0023 0.0031 0.0031
Schistosoma mansoni alpha-1 adrenergic receptor 0.0131 0.032 0.0542
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0095 0.2561
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus multilocularis glycogen phosphorylase 0.0116 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Echinococcus multilocularis neuropeptide FF receptor 2 0.0131 0.032 0.032
Plasmodium vivax SET domain protein, putative 0.0036 0.0065 0.0776
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0024 0.0047
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0125 0.0617
Schistosoma mansoni tyrosine kinase 0.0012 0.0003 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0131 0.032 0.032
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Brugia malayi ecdysone receptor 0.0014 0.0008 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0178 0.0349
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Brugia malayi Cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0002
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0012 0.0012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0131 0.032 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Schistosoma mansoni hypothetical protein 0.005 0.0105 0.0177
Brugia malayi putative neuropeptide receptor NPR1 0.0131 0.032 0.0628
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0145 0.0358 0.0703
Echinococcus multilocularis Diacylglycerol kinase theta 0.0017 0.0015 0.0015
Brugia malayi intracellular kinase 0.0057 0.0123 0.0241
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0098 0.0479
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0012 0.0002 0.0002
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.0123 0.0123
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0017 0.0017 0.0033
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi beta-lactamase family protein 0.0037 0.0068 0.0133
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0008 0.0015
Onchocerca volvulus 0.0036 0.0065 0.0128
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0014 0.0014
Leishmania major protein kinase, putative 0.0014 0.0008 0.0036
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0167 0.2312
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0011 0.0018
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0111 0.0111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.008 0.0185 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.008 0.0185 0.0363
Leishmania major DNA polymerase eta, putative 0.0017 0.0017 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.005 0.0098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.008 0.0185 0.3104
Echinococcus multilocularis neuropeptide receptor 0.0131 0.032 0.032
Brugia malayi hypothetical protein 0.0017 0.0017 0.0033
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0131 0.032 0.0629
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Brugia malayi hypothetical protein 0.0172 0.0429 0.0841
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0077 0.0406
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0014 0.0056
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0077 0.0406
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0377 0.0377
Onchocerca volvulus Bile acid receptor homolog 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni hypothetical protein 0.0035 0.0064 0.0108
Loa Loa (eye worm) ctsf protein 0.002 0.0024 0.0047
Echinococcus multilocularis glycogen phosphorylase 0.0116 0.028 0.028
Loa Loa (eye worm) cysteine protease 0.002 0.0024 0.0047
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.0123 0.0607
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0142 0.0279
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0014 0.0367
Brugia malayi beta-lactamase family protein 0.0037 0.0068 0.0133
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0326 0.084 0.084
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0758 0.1988 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Plasmodium vivax amine transporter, putative 0.0326 0.084 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.005 0.0099
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Brugia malayi CCR4 0.0016 0.0014 0.0027
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0015 0.0175
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0016 0.0013 0.0024
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0068 0.0115
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Schistosoma mansoni rab6-interacting 0.0064 0.0142 0.024
Brugia malayi metabotropic glutamate receptor type 2 0.0016 0.0013 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0077 0.0374
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.0123 0.0123
Trichomonas vaginalis taga, putative 0.0011 0 0.0004
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1856
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0068 0.226
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0008 0.0013
Brugia malayi cytochrome P450 0.004 0.0077 0.015
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0035 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.044 0.6089
Brugia malayi GnHR receptor homolog 0.0131 0.032 0.0628
Echinococcus multilocularis G protein coupled receptor 139 0.0131 0.032 0.032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Echinococcus granulosus biogenic amine 5HT receptor 0.0131 0.032 0.032
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0035 0.0035
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.0123 0.1464
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Onchocerca volvulus 0.0064 0.0142 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0024 0.0328
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0123 0.4105
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0014 0.0069
Onchocerca volvulus 0.0017 0.0015 0.0029
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0358 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0065 0.011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0131 0.032 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi neuropeptide F receptor 0.0131 0.032 0.0628
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Brugia malayi Tyrosine-protein kinase abl-1 0.0012 0.0003 0.0005
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0092 0.0092
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0017 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0829
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0142 0.0142
Brugia malayi protein-tyrosine kinase 0.0042 0.0081 0.0159
Trypanosoma brucei unspecified product 0.0041 0.008 0.0403
Schistosoma mansoni single-minded 0.0051 0.0107 0.0181
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0131 0.032 0.0542
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.005 0.0098
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0003 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0131 0.032 0.0628
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0094 0.0159
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0106 0.1262
Loa Loa (eye worm) DR-78 0.0014 0.0008 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0077 0.1289
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0031 0.0423
Echinococcus granulosus death domain containing protein 0.0015 0.0012 0.0012
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Echinococcus granulosus cathepsin l1 0.002 0.0024 0.0024
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0014 0.0068
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0035 0.0035
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0156 0.0771
Brugia malayi MH2 domain containing protein 0.0119 0.0288 0.0566
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0013
Echinococcus granulosus Glycosyl transferase family 35 0.0116 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0101 0.0508
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0055 0.0649
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0008 0.0013
Brugia malayi Glutamate receptor 2 precursor 0.0153 0.0377 0.074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0483
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0024 0.0637
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0064 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0014 0.0161
Onchocerca volvulus 0.002 0.0024 0.0046
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi Abnormal catecholamine distribution protein 1 0.0567 0.1479 0.2904
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Schistosoma mansoni protein kinase C mu 0.0017 0.0017 0.0028
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0326 0.084 0.1649
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis glutamate receptor 2 0.0112 0.0269 0.0269
Loa Loa (eye worm) norepinephrine transporter 0.1923 0.5091 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis nmda type glutamate receptor 0.0138 0.0339 0.0339
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Echinococcus granulosus GPCR family 2 0.008 0.0184 0.0184
Loa Loa (eye worm) glycogen phosphorylase 0.0116 0.028 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0055 0.0753
Onchocerca volvulus 0.0046 0.0094 0.0184
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0758 0.1988 0.3905
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Treponema pallidum sodium- and chloride- dependent transporter 0.1923 0.5091 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.005 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Schistosoma mansoni loxhd1 0.0064 0.0142 0.024
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0046 0.0077
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus multilocularis orexin receptor type 2 0.0131 0.032 0.032
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0014 0.0056
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Echinococcus multilocularis protein kinase shaggy 0.0057 0.0123 0.0123
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Brugia malayi Doublecortin family protein 0.0064 0.0142 0.0278
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0173 0.0431 0.0431
Echinococcus granulosus geminin 0.0703 0.1842 0.1842
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0069 0.0349
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0068 0.0933
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0068 0.0115
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0057 0.0121 0.0121
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.005 0.005
Loa Loa (eye worm) glutamate receptor 1 0.0153 0.0377 0.0741
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0839
Schistosoma mansoni polycystin 1-related 0.0064 0.0142 0.024
Echinococcus granulosus RUN 0.0064 0.0142 0.0142
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0111 0.0217
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0003
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.0123 0.1467
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Brugia malayi nuclear receptor NHR-88 0.0014 0.0008 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0068 0.1143
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0 0.0003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0015 0.0062
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0014 0.0069
Echinococcus granulosus c src tyrosine kinase 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0131 0.032 0.0628
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0077 0.1289
Onchocerca volvulus 0.0283 0.0724 0.1422
Giardia lamblia Glycogen phosphorylase 0.0116 0.028 1
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0008 0.0013
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0092 0.0092
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0169 0.0419 0.0419
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0015 0.0248
Brugia malayi hypothetical protein 0.0014 0.0008 0.0015
Echinococcus granulosus unc 13 munc13 0.0017 0.0015 0.0015
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0014 0.0161
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Echinococcus granulosus muscleblind protein 0.0145 0.0358 0.0358
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.005 0.0105 0.1754
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0068 0.1143
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0072 0.0072
Brugia malayi Cation transporter family protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0111 0.0217
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0094 0.0159
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.008 0.0185 0.6413
Echinococcus granulosus allatostatin A receptor 0.0131 0.032 0.032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Schistosoma mansoni rab6-interacting 0.0064 0.0142 0.024
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0035 0.0035
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0014 0.0068
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0281 0.0552
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0326 0.084 0.084
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis geminin 0.0703 0.1842 0.1842
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0094 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0131 0.032 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.005 0.0099
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0008 0.0008
Schistosoma mansoni intermediate filament proteins 0.0028 0.0045 0.0076
Echinococcus granulosus single minded 2 0.0042 0.0081 0.0081
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.165
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0094 0.0094
Leishmania major C-8 sterol isomerase-like protein 0.0758 0.1988 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Brugia malayi hypothetical protein 0.0326 0.084 0.1649
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0081 0.0081
Brugia malayi Ras association domain family 1 isoform A 0.0017 0.0015 0.0029
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Echinococcus granulosus lamin b receptor 0.0092 0.0216 0.0216
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0017 0.0017 0.0033
Onchocerca volvulus 0.0024 0.0035 0.0068
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0248 0.0632 0.1241
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0014 0.0027
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0416 0.0817
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Schistosoma mansoni glycogen phosphorylase 0.0116 0.028 0.0475
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.005 0.0098
Echinococcus granulosus neuropeptide FF receptor 2 0.0131 0.032 0.032
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0014 0.0161
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0068 0.1143
Echinococcus granulosus nmda type glutamate receptor 0.0098 0.0231 0.0231
Leishmania major hypothetical protein, conserved 0.0037 0.0068 0.0342
Echinococcus multilocularis protein kinase c epsilon type 0.0017 0.0017 0.0017
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0146 0.0286
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Echinococcus granulosus Protein kinase C brain isozyme 0.0017 0.0017 0.0017
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0345 0.0677
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0062
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0055 0.147
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0046 0.009
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0008 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1923 0.5091 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0024 0.0637
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0077 0.0406
Echinococcus granulosus somatostatin receptor 0.0131 0.032 0.032
Echinococcus multilocularis dna polymerase eta 0.0017 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Entamoeba histolytica hypothetical protein 0.0024 0.0035 0.094
Echinococcus multilocularis musashi 0.0028 0.0045 0.0045
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0013 0.0021
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0035 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.005 0.005
Schistosoma mansoni lipoxygenase 0.0323 0.0829 0.1405
Brugia malayi SRC-1 0.0046 0.0092 0.0181
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0219
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0017 0.0207
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0043 0.0201
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0111 0.0217
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0111 0.0217
Brugia malayi G-protein coupled receptor 0.0131 0.032 0.0628
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0092 0.0092
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0142 0.0279
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0077 0.0406
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.032 0.032
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Echinococcus multilocularis nmda type glutamate receptor 0.0098 0.0231 0.0231
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0024 0.028
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Brugia malayi ORL1-like opioid receptor 0.0131 0.032 0.0628
Echinococcus multilocularis cysteine protease 0.002 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0173 0.0432 0.0849
Schistosoma mansoni protein kinase 0.0019 0.0022 0.0037
Onchocerca volvulus 0.0024 0.0035 0.0068
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0094 0.0159
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0022 0.0043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0015 0.003
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0068 0.1143
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0046 0.009
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0142 0.1688
Trypanosoma brucei unspecified product 0.0012 0.0002 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus granulosus tyrosine protein kinase HCK 0.0037 0.007 0.007
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0017 0.0083
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Cathepsin L-like precursor 0.0013 0.0006 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0008 0.0016
Schistosoma mansoni synaptojanin 0.0016 0.0014 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0432 0.0848
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.008 0.0403
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0023 0.0274
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0393 0.0772
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Schistosoma mansoni nAChR subunit 0.0024 0.0035 0.0059
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0024 0.0047
Brugia malayi tailless protein 0.0014 0.0008 0.0015
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0055 0.0646
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0033
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.008 0.0185 0.5471
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0081 0.0081
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0077 0.1289
Mycobacterium leprae Probable lipase LipE 0.0037 0.0068 0.226
Brugia malayi diacylglycerol kinase 0.0017 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0111 0.0111
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0326 0.084 0.084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.008 0.0185 0.0185
Brugia malayi hypoxia-induced factor 1 0.0159 0.0393 0.0772
Schistosoma mansoni cript-related 0.0016 0.0014 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Onchocerca volvulus 0.0016 0.0014 0.0027
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0072 0.0072
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0106 0.1262
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0081 0.0081
Echinococcus granulosus tyrosine kinase 0.0019 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0017 0.0015 0.003
Echinococcus multilocularis serotonin receptor 0.0131 0.032 0.032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0184 0.0184
Brugia malayi Protein kinase domain containing protein 0.0016 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Serotonin receptor 0.0131 0.032 0.0628
Trypanosoma brucei unspecified product 0.0012 0.0002 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Onchocerca volvulus 0.0028 0.0046 0.009
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0125 0.0246
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0077 0.0406
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis transcription factor Dp 1 0.0087 0.0201 0.0201
Schistosoma mansoni DNA polymerase eta 0.0017 0.0017 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0077 0.1289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0015 0.0015
Brugia malayi conserved hypotetical protein 0.0014 0.0008 0.0015
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0111 0.0111
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0049 0.0101 0.1397
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0006 0.0083
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.1013 0.2668 0.5241
Schistosoma mansoni hypothetical protein 0.0064 0.0142 0.024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0106 0.1465
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.032 0.0542
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0131 0.032 0.032
Echinococcus granulosus microtubule associated protein 2 0.2227 0.59 0.59
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0156
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0111 0.0111
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.032 0.032
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0024 0.0106
Brugia malayi follicle stimulating hormone receptor 0.0378 0.0978 0.192
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0024 0.028
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0017 0.0088
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0147 0.2462
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0111 0.0111
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Echinococcus granulosus N chimaerin 0.0021 0.0027 0.0027
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0016 0.0013 0.0025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0008 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0327 0.0841 0.1425
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.008 0.0185 0.0929
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0173 0.0431 0.073
Echinococcus granulosus sodium and chloride dependent glycine 0.0326 0.084 0.084
Brugia malayi Serotonin receptor 0.0131 0.032 0.0628
Onchocerca volvulus 0.002 0.0024 0.0046
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0077 0.1289
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0217
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Schistosoma mansoni sodium-dependent amino acid transporter 0.0326 0.084 0.1423
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0045 0.0089
Loa Loa (eye worm) hypothetical protein 0.0127 0.0309 0.0607
Onchocerca volvulus 0.0326 0.084 0.1649
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0012 0.0003 0.0004
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0131 0.032 0.032
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0146 0.0146
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Onchocerca volvulus 0.0019 0.0022 0.0043
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.005 0.005
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0068 0.0068
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.015 0.0369 0.0625
Echinococcus multilocularis fmrfamide receptor 0.0131 0.032 0.032
Onchocerca volvulus 0.0017 0.0015 0.0029
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0167 0.199
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0011 0.0021
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Schistosoma mansoni protein kinase C 0.0017 0.0015 0.0025
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0072 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0021 0.0027 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0017 0.0274
Echinococcus multilocularis FTZ F1 alpha 0.003 0.005 0.005
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Echinococcus multilocularis lamin b receptor 0.0092 0.0216 0.0216
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0092 0.0092
Loa Loa (eye worm) cytochrome P450 0.004 0.0077 0.0151
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0014 0.0056
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0281 0.4727
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.005 0.005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0131 0.032 0.032
Brugia malayi Muscleblind-like protein 0.0145 0.0358 0.0702
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0092 0.0092
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.008 0.0185 0.0917
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0068 0.0133
Echinococcus granulosus nAChR subunit 0.0053 0.0111 0.0111
Onchocerca volvulus 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0111 0.0111
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.032 0.032
Entamoeba histolytica diacylglycerol kinase, putative 0.0017 0.0015 0.0406
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0012 0.0023
Schistosoma mansoni rac gtpase activating protein 0.0017 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0254 0.0646 0.1268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.005 0.0098
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0035 0.0035
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Schistosoma mansoni ap endonuclease 0.008 0.0185 0.0313
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.005 0.005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) solute carrier family 6 member 4 0.1923 0.5091 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) TK protein kinase 0.0037 0.007 0.0137
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0019 0.0022 0.0043
Leishmania major cytochrome p450-like protein 0.004 0.0077 0.0385
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0146 0.0285
Entamoeba histolytica protein kinase, putative 0.0037 0.007 0.188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.005 0.0098
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Echinococcus granulosus tyrosine protein kinase Lyn 0.0046 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni hypothetical protein 0.0703 0.1842 0.3121
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0055 0.0649
Schistosoma mansoni tyrosine kinase 0.0012 0.0003 0.0004
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0055 0.0646
Brugia malayi larval opioid receptor 0.0131 0.032 0.0628
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0024
Echinococcus granulosus tachykinin peptides receptor 99D 0.0131 0.032 0.032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0146 0.0286
Echinococcus multilocularis vesicular acetylcholine transporter 0.1122 0.2957 0.2957
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0216 0.1072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.005 0.0098
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.005 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Mycobacterium leprae putative cytochrome p450 0.004 0.0077 0.2574
Plasmodium vivax hypothetical protein, conserved 0.0326 0.084 1
Echinococcus multilocularis glutamate receptor 2 0.0169 0.0419 0.0419
Echinococcus granulosus fmrfamide receptor 0.0131 0.032 0.032
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0035 0.0068
Onchocerca volvulus Cathepsin L homolog 0.002 0.0024 0.0046
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0014 0.0014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Loa Loa (eye worm) raf kinase 0.0479 0.1246 0.2447
Trichomonas vaginalis glycogen phosphorylase, putative 0.0116 0.028 0.3877
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.005 0.0085
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1923 0.5091 0.8629
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0111 0.0111
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.005 0.0085
Schistosoma mansoni hypothetical protein 0.0298 0.0765 0.1296
Onchocerca volvulus 0.0326 0.084 0.1649
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0281 0.0552
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus dna polymerase kappa 0.0049 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0131 0.032 0.032
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0012 0.0002 0.0002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Echinococcus granulosus 7TM GPCR rhodopsin 0.0131 0.032 0.032
Schistosoma mansoni synaptojanin 0.0016 0.0014 0.0023
Echinococcus granulosus 7tm_1 domain containing protein 0.0131 0.032 0.032
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0024 0.0024
Schistosoma mansoni netrin receptor unc5 0.0015 0.0012 0.0019
Trypanosoma brucei protein kinase, putative 0.0057 0.0123 0.062
Schistosoma mansoni lamin 0.0028 0.0045 0.0076
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni glycogen phosphorylase 0.005 0.0105 0.0177
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Onchocerca volvulus 0.0064 0.0142 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0017 0.0017 0.0017
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0111 0.0217
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0131 0.032 0.0542
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0167 0.2312
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0077 0.0406
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0184 0.0362
Brugia malayi nuclear hormone receptor 0.0014 0.0008 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0323 0.0829 0.0829
Echinococcus granulosus protein kinase c epsilon type 0.0017 0.0017 0.0017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0326 0.084 0.1423
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0068 0.1143
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0125 0.2668
Brugia malayi putative neuropeptide receptor 0.0131 0.032 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Brugia malayi ecdysteroid receptor 0.003 0.005 0.0098
Echinococcus multilocularis NMDA receptor 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.008 0.0184 0.0362
Echinococcus granulosus glutamate receptor 2 0.0112 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi hypothetical protein 0.0064 0.0142 0.0278
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Brugia malayi Pre-SET motif family protein 0.0248 0.0632 0.124
Trichomonas vaginalis set domain proteins, putative 0.0283 0.0723 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0084
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0326 0.084 1
Echinococcus granulosus vesicular acetylcholine transporter 0.1122 0.2957 0.2957
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0111 0.0111
Brugia malayi Glutamate receptor 1 precursor 0.0153 0.0377 0.074
Echinococcus granulosus lamin 0.0028 0.0045 0.0045
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0111 0.0111
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0014 0.0367
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0006 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0017 0.0086
Schistosoma mansoni histamine h1 receptor 0.0131 0.032 0.0542
Echinococcus multilocularis tyrosine protein kinase Abl 0.0012 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0035 0.0069
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis g-protein coupled receptor 0.0131 0.032 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0012 0.0002 0.0002
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0111 0.0217
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.165
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0035 0.0069
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0142 0.1688
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0038 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Brugia malayi Death domain containing protein 0.0015 0.0012 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Leishmania major extracellular receptor, putative 0.0016 0.0013 0.0062
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0022 0.0043
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0081 0.0081
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0106 0.0106
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.0111 0.0217
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0021 0.0027 0.0027
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0185 0.2197
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Toxoplasma gondii ABC1 family protein 0.0037 0.0068 0.0812
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0111
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0014 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus granulosus neuropeptide receptor 0.0131 0.032 0.032
Schistosoma mansoni coup transcription factor 0.003 0.005 0.0085
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.032 0.0629
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.008 0.0185 0.0928
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0075
Echinococcus granulosus glutamate receptor 2 0.0169 0.0419 0.0419
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Brugia malayi RNA binding protein 0.0066 0.0146 0.0285
Schistosoma mansoni ATP-binding cassette transporter 0.0153 0.0378 0.0639
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0085 0.0166
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0281 0.1414
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0088
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0024 0.004
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0841
Onchocerca volvulus Cathepsin F homolog 0.002 0.0024 0.0046
Echinococcus multilocularis neuropeptide receptor 0.0131 0.032 0.032
Brugia malayi mbt repeat family protein 0.0046 0.0094 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0646 0.1268
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0064 0.0108
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.032 0.032
Brugia malayi exodeoxyribonuclease III family protein 0.008 0.0185 0.0362
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Echinococcus granulosus synaptojanin 1 0.0016 0.0014 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0006 0.016
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0017 0.0086
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.032 0.032
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0006 0.0069
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0024 0.028
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0045 0.0088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Echinococcus multilocularis dro:myosuppressin receptor 0.0131 0.032 0.032
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.015 0.0369 1
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0016 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0077 0.0406
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Onchocerca volvulus 0.0017 0.0015 0.0029
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) beta-lactamase 0.0037 0.0068 0.0134
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.032 0.0629
Schistosoma mansoni adenoreceptor 0.0131 0.032 0.0542
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.005 0.0098
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0077 0.0406
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629

Activities

Activity type Activity value Assay description Source Reference
AUC (ADMET) = 1000 ng.hr/ml AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751
AUC (ADMET) = 1800 ng.hr/ml AUC (0-inf) in Sprague-Dawley rat at 5 mg/kg, po up to 8 hrs ChEMBL. 17585751
CL (ADMET) = 1.1 L/hr.Kg Clearance in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751
F (ADMET) = 35 % Oral bioavailability in Sprague-Dawley rat at 5 mg/kg ChEMBL. 17585751
IC50 (binding) = 3.1 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as acid-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 3.1 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as acid-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 4.9 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as capsaicin-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 4.9 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as capsaicin-induced Ca2+ influx ChEMBL. 17585751
Solubility = 5 ug ml-1 Solubility in PBS ChEMBL. 17585751
Solubility = 34 ug ml-1 Solubility in SIF ChEMBL. 17585751
Solubility >= 200 ug ml-1 Solubility in 0.01N HCl ChEMBL. 17585751
t1/2 (ADMET) = 2.4 hr Half life in Sprague-Dawley rat at 1 mg/kg, iv ChEMBL. 17585751
Vss (ADMET) = 2.9 L/Kg Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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