Detailed information for compound 427971

Basic information

Technical information
  • TDR Targets ID: 427971
  • Name: N-[4-[6-[4-[(1R)-1-(4-fluorophenyl)ethyl]pipe razin-1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazo l-2-yl]acetamide
  • MW: 492.568 | Formula: C25H25FN6O2S
  • H donors: 1 H acceptors: 4 LogP: 4.3 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1sc2c(n1)c(ccc2)Oc1ncnc(c1)N1CCN(CC1)[C@@H](c1ccc(cc1)F)C
  • InChi: 1S/C25H25FN6O2S/c1-16(18-6-8-19(26)9-7-18)31-10-12-32(13-11-31)22-14-23(28-15-27-22)34-20-4-3-5-21-24(20)30-25(35-21)29-17(2)33/h3-9,14-16H,10-13H2,1-2H3,(H,29,30,33)/t16-/m1/s1
  • InChiKey: QUHZTEMPQQZPNB-MRXNPFEDSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[4-[[6-[4-[(1R)-1-(4-fluorophenyl)ethyl]-1-piperazinyl]-4-pyrimidinyl]oxy]-1,3-benzothiazol-2-yl]acetamide
  • N-[4-[6-[4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]ethanamide
  • N-[4-[6-[4-[(1R)-1-(4-fluorophenyl)ethyl]piperazino]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Vanilloid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis lamin dm0 0.0028 0.0045 0.0045
Echinococcus granulosus myotubularin protein 13 0.0017 0.0015 0.0015
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0111 0.0111
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0179
Echinococcus granulosus nmda type glutamate receptor 0.0138 0.0339 0.0339
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Echinococcus multilocularis neuropeptide s receptor 0.0131 0.032 0.032
Loa Loa (eye worm) acetyltransferase 0.0173 0.0431 0.0847
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0035 0.0068
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0008 0.0015
Echinococcus multilocularis sex peptide receptor 0.0131 0.032 0.032
Schistosoma mansoni atypical protein kinase C 0.0017 0.0017 0.0028
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0077 0.0374
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0008 0.0008
Schistosoma mansoni cytochrome P450 0.004 0.0077 0.013
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.013 0.0641
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0072 0.0072
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0012 0.0022
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0501 0.0501
Schistosoma mansoni glycogen phosphorylase 0.0116 0.028 0.0475
Onchocerca volvulus Neuropeptide F receptor homolog 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0131 0.032 0.0629
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0013 0.0025
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0181 0.0181
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0014 0.0068
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0127 0.0309 0.0524
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0017 0.0017
Echinococcus multilocularis somatostatin receptor 0.0131 0.032 0.032
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0017 0.0029
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0085 0.0085
Brugia malayi Dopamine receptor 0.0131 0.032 0.0628
Brugia malayi polk-prov protein 0.0037 0.0069 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.015 0.0369 0.0369
Echinococcus multilocularis Rac GTPase activating protein 1 0.0017 0.0015 0.0015
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.1255 0.2127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.005 0.005
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0094 0.0159
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.008 0.0185 0.5004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus multilocularis allatostatin A receptor 0.0131 0.032 0.032
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0065 0.0065
Echinococcus multilocularis synaptic vesicular amine transporter 0.0567 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.1013 0.2668 0.5241
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0035 0.0059
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0015 0.0075
Schistosoma mansoni hypothetical protein 0.004 0.0077 0.013
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0125 0.0246
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0014 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0077 0.0374
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0013 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0057 0.0121 0.0121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Echinococcus multilocularis serotonin transporter 0.1923 0.5091 0.5091
Brugia malayi RE15519p 0.0131 0.032 0.0628
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.065 0.1277
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Schistosoma mansoni vesicular amine transporter 0.0567 0.1479 0.2506
Schistosoma mansoni sodium/chloride dependent transporter 0.0326 0.084 0.1423
Trichomonas vaginalis glycogen phosphorylase, putative 0.0116 0.028 0.3877
Echinococcus granulosus dna polymerase eta 0.0017 0.0017 0.0017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0065 0.0065
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0181 0.0181
Trichomonas vaginalis esterase, putative 0.0037 0.0068 0.0943
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0012
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0111 0.0111
Echinococcus granulosus protein kinase shaggy 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0131 0.032 0.032
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0131 0.032 0.0629
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Onchocerca volvulus 0.0057 0.0123 0.0241
Brugia malayi Cation transporter family protein 0.0127 0.0309 0.0607
Echinococcus multilocularis Glycosyl transferase, family 35 0.0116 0.028 0.028
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0088
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.005 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis protein kinase c eta type 0.0017 0.0015 0.0015
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0077 0.0387
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0017 0.007
Onchocerca volvulus 0.0131 0.032 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0012 0.0003 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0027 0.0052
Echinococcus multilocularis cysteine protease 0.002 0.0024 0.0024
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0169 0.0419 0.0419
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0016 0.0013 0.0013
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0014 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.005 0.0099
Brugia malayi Inositol-1 0.0074 0.0167 0.0328
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0011 0.0011
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0 0.0004
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0095 0.1124
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.005 0.0098
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0105 0.2827
Echinococcus multilocularis dna polymerase kappa 0.0049 0.0101 0.0101
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0085 0.0167
Brugia malayi Cytochrome P450 family protein 0.0058 0.0125 0.0245
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0077 0.1289
Echinococcus multilocularis unc 13 (munc13) 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0035 0.0416
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0027 0.0045
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.002 0.0024 0.0637
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0068 0.033
Schistosoma mansoni inositol monophosphatase 0.0074 0.0167 0.0283
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0055 0.008
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0016 0.0013 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0013 0.0021
Echinococcus granulosus glycogen phosphorylase 0.0116 0.028 0.028
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Echinococcus granulosus biogenic amine 5HT receptor 0.0131 0.032 0.032
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.005 0.0098
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0092 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0101 0.0508
Schistosoma mansoni vesicular acetylcholine transporter 0.1122 0.2957 0.5012
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0045 0.0089
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068
Loa Loa (eye worm) melatonin receptor type 1A 0.0131 0.032 0.0629
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0014 0.0191
Echinococcus granulosus raf serine:threonine protein kinase 0.0483 0.1255 0.1255
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1122 0.2957 0.5808
Brugia malayi beta-lactamase 0.0037 0.0068 0.0133
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.005 0.0085
Brugia malayi RhoGAP domain containing protein 0.0017 0.0015 0.0029
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0125 0.0617
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0367
Loa Loa (eye worm) hypothetical protein 0.0145 0.0358 0.0703
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0167 0.4646
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Entamoeba histolytica hypothetical protein 0.0017 0.0015 0.0406
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Echinococcus granulosus atrial natriuretic peptide receptor 0.0016 0.0013 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0123 0.1704
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0077 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Schistosoma mansoni tyrosine kinase 0.0019 0.0022 0.0037
Brugia malayi AKH receptor 0.0131 0.032 0.0628
Brugia malayi isocitrate dehydrogenase 0.0017 0.0015 0.0029
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0106 0.1465
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0081 0.0081
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Onchocerca volvulus 0.002 0.0024 0.0046
Echinococcus granulosus G protein coupled receptor 139 0.0131 0.032 0.032
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Onchocerca volvulus 0.0028 0.0045 0.0088
Giardia lamblia DINP protein human, muc B family 0.0025 0.0038 0.0889
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Echinococcus granulosus serotonin receptor 0.0131 0.032 0.032
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.032 0.0542
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.032 0.032
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.0022 0.0022
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.005 0.0098
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0017 0.0088
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.032 0.032
Leishmania major cytochrome p450-like protein 0.004 0.0077 0.0385
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0006 0.0083
Schistosoma mansoni vav2 0.0021 0.0027 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0123 0.3335
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0014 0.0161
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus granulosus sex peptide receptor 0.0131 0.032 0.032
Echinococcus multilocularis tyrosine kinase 0.0019 0.0022 0.0022
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0017 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0077 0.1289
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0077 0.0406
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.032 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0123 0.1704
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0123 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Brugia malayi neuropeptide F receptor 0.0131 0.032 0.0628
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.0123 0.0242
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0011 0.0011
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0111 0.0218
Schistosoma mansoni nuclear receptor 0.0014 0.0008 0.0013
Echinococcus granulosus peptide allatostatin:somatostatin 0.0131 0.032 0.032
Schistosoma mansoni thyroid hormone receptor 0.003 0.005 0.0085
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.005 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0014 0.0056
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0004
Echinococcus multilocularis GPCR, family 2 0.008 0.0184 0.0184
Echinococcus multilocularis Ankyrin 0.0016 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0011 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2072 0.2072
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0077 0.0385
Onchocerca volvulus 0.0037 0.0068 0.0133
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0173 0.0859
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0077 0.1289
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0156
Echinococcus granulosus neuropeptide receptor 0.0131 0.032 0.032
Entamoeba histolytica hypothetical protein 0.0016 0.0013 0.0335
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0281 0.0476
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0006 0.0069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Echinococcus granulosus synaptic vesicular amine transporter 0.0567 0.1479 0.1479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0092 0.0092
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0092 0.0092
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0131 0.032 0.032
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.032 0.0629
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0646 0.1268
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Echinococcus multilocularis RUN 0.0064 0.0142 0.0142
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.005 0.0085
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0013
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0111 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Brugia malayi Melatonin receptor type 1A 0.0131 0.032 0.0628
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0185 0.2197
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0147 0.5107
Echinococcus granulosus neuropeptide receptor A26 0.0131 0.032 0.032
Brugia malayi protein kinase C3,putative 0.0017 0.0017 0.0032
Treponema pallidum exodeoxyribonuclease (exoA) 0.008 0.0185 0.0337
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.0123 0.0208
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.005 0.005
Echinococcus granulosus tyrosine kinase 0.0042 0.0081 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0024
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Brugia malayi phosphofructokinase 0.0117 0.0281 0.0552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis DNA polymerase eta, putative 0.0049 0.0101 0.1397
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0017 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0035 0.0059
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Leishmania major cytochrome p450-like protein 0.0058 0.0125 0.0628
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Schistosoma mansoni hypothetical protein 0.0057 0.0121 0.0205
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.0111 0.0111
Plasmodium vivax vivapain-2 0.002 0.0024 0.028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Loa Loa (eye worm) TYRA-2 protein 0.0131 0.032 0.0629
Echinococcus granulosus glutamate receptor subunit protein glur 0.0057 0.0121 0.0121
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0035 0.0035
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0015 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0006 0.0085
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Loa Loa (eye worm) RecQ helicase 0.0023 0.0031 0.006
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0167 0.4527
Echinococcus granulosus tar DNA binding protein 0.0066 0.0146 0.0146
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0167 0.0167
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0024 0.0024
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0111 0.0217
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.015 0.0369 0.0724
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0185 0.2555
Brugia malayi G protein-coupled receptor F59B2.13 0.0131 0.032 0.0628
Echinococcus multilocularis myotubularin protein 13 0.0017 0.0015 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0014 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0123 0.3335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0281 0.0552
Toxoplasma gondii exonuclease III APE 0.008 0.0185 0.22
Onchocerca volvulus Putative nachr subunit 0.0053 0.0111 0.0217
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0068 0.0933
Onchocerca volvulus 0.0127 0.0309 0.0607
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0131 0.032 0.0542
Brugia malayi C1-like domain containing protein 0.0017 0.0017 0.0032
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0024 0.004
Echinococcus granulosus cathepsin l1 0.0013 0.0006 0.0006
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0089
Echinococcus granulosus hypothetical protein 0.0131 0.032 0.032
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0131 0.032 0.0628
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0167 0.0167
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0092 0.0092
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0018 0.0075
Plasmodium falciparum transporter, putative 0.0326 0.084 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0077 0.1289
Onchocerca volvulus 0.002 0.0024 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.005 0.0085
Echinococcus multilocularis protein kinase c iota type 0.0017 0.0017 0.0017
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0111 0.0217
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0094 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.0048 0.0098 0.0192
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0068 0.1143
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0057 0.0121 0.0121
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.015 0.0369 0.0369
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0646 0.1268
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0035 0.0068
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0185
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0022
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0006 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0077 0.1289
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0046 0.009
Trypanosoma brucei C-14 sterol reductase, putative 0.0092 0.0216 0.1084
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0086
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0077 0.0406
Echinococcus multilocularis 0.004 0.0077 0.0077
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0131 0.032 0.032
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.0123 0.0618
Onchocerca volvulus 0.0014 0.0008 0.0015
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0387 0.1002 0.1968
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0008 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0014 0.0068
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0012 0.0012
Brugia malayi Cytochrome P450 family protein 0.0058 0.0125 0.0245
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Echinococcus granulosus orexin receptor type 2 0.0131 0.032 0.032
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0017
Schistosoma mansoni microtubule-associated protein tau 0.2227 0.59 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.0022 0.0022
Brugia malayi Dopamine receptor protein 2 0.0131 0.032 0.0628
Brugia malayi Cytochrome P450 family protein 0.004 0.0077 0.015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.008 0.0185 0.0917
Schistosoma mansoni lipoxygenase 0.0207 0.0521 0.0882
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0111 0.0187
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0111 0.0111
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Loa Loa (eye worm) hypothetical protein 0.0127 0.0309 0.0607
Echinococcus granulosus glutamate receptor NMDA 0.0082 0.0188 0.0188
Echinococcus multilocularis raf serine:threonine protein kinase 0.0483 0.1255 0.1255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus granulosus histone acetyltransferase KAT2B 0.0168 0.0418 0.0418
Chlamydia trachomatis glycogen phosphorylase 0.0116 0.028 0.3336
Brugia malayi mbt repeat family protein 0.0046 0.0094 0.0184
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Loa Loa (eye worm) serotonin transporter b 0.1923 0.5091 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0021 0.0027 0.0027
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0008 0.0008
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0111 0.0111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0035 0.0068
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0101 0.154
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0017 0.0441
Echinococcus granulosus alpha 1A adrenergic receptor 0.0131 0.032 0.032
Schistosoma mansoni ap endonuclease 0.008 0.0185 0.0313
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0069 0.0349
Schistosoma mansoni glutamate receptor NMDA 0.0325 0.0835 0.1414
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.005 0.0085
Brugia malayi intermediate filament protein 0.0028 0.0045 0.0088
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0281 0.0281
Brugia malayi 6-phosphofructokinase 0.0117 0.0282 0.0552
Brugia malayi diacylglycerol kinase 0.0017 0.0015 0.0029
Onchocerca volvulus 0.0131 0.032 0.0628
Onchocerca volvulus 0.0028 0.0046 0.009
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0031 0.0031
Brugia malayi Cation transporter family protein 0.0053 0.0111 0.0217
Trypanosoma cruzi extracellular receptor, putative 0.0016 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0002 0.0002
Loa Loa (eye worm) TK protein kinase 0.0042 0.0081 0.0159
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0281 0.0527
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Echinococcus granulosus glutamate NMDA receptor subunit 0.0325 0.0835 0.0835
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0077 0.1289
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0014 0.0023
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0018 0.0087
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0013
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0065 0.0779
Loa Loa (eye worm) glutamate receptor 0.0016 0.0013 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0131 0.032 0.032
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0131 0.032 0.032
Echinococcus multilocularis serotonin receptor 0.0131 0.032 0.032
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0046 0.009
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi hypothetical protein 0.0035 0.0064 0.0125
Brugia malayi vesicular acetylcholine transporter unc-17 0.1122 0.2957 0.5808
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0008 0.0013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Echinococcus multilocularis synaptojanin 1 0.0016 0.0014 0.0014
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0094 0.0184
Entamoeba histolytica hypothetical protein 0.0028 0.0046 0.1239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Entamoeba histolytica glycogen phosphorylase, putative 0.0116 0.028 0.7597
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0829
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0281 0.0281
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0016 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.005 0.0099
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.005 0.0098
Onchocerca volvulus 0.002 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus metabotropic glutamate receptor 2 0.0016 0.0013 0.0013
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0017 0.0465
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.005 0.0085
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0281 0.762
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0326 0.084 0.084
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0015 0.0175
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0017 0.0032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0131 0.032 0.0628
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0288 0.0567
Onchocerca volvulus Glycogen phosphorylase homolog 0.0116 0.028 0.055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0367
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0017 0.0032
Brugia malayi acetyltransferase, GNAT family protein 0.0173 0.0431 0.0846
Onchocerca volvulus 0.003 0.005 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.005 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0758 0.1988 0.3905
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Loa Loa (eye worm) MBCTL1 0.0053 0.0111 0.0219
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0037
Brugia malayi Cathepsin L-like precursor 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0044
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0111 0.0111
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.0646
Schistosoma mansoni thyroid hormone receptor 0.003 0.005 0.0085
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Trypanosoma brucei C-8 sterol isomerase, putative 0.0758 0.1988 1
Plasmodium vivax vivapain-2 0.002 0.0024 0.028
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0014 0.0161
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0014 0.0161
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0111 0.0111
Schistosoma mansoni myosin xvIII 0.0131 0.032 0.0542
Entamoeba histolytica protein kinase, putative 0.0057 0.0123 0.3335
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.005 0.0105 0.1703
Schistosoma mansoni unc-13 (munc13) 0.0019 0.0021 0.0035
Echinococcus granulosus dro:myosuppressin receptor 0.0131 0.032 0.032
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0323 0.0829 0.0829
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Brugia malayi Raf kinase 0.0466 0.1211 0.2378
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Schistosoma mansoni inositol monophosphatase 0.0074 0.0167 0.0283
Mycobacterium ulcerans DNA polymerase IV 0.0049 0.0101 0.154
Schistosoma mansoni neuropeptide f receptor 76f 0.0131 0.032 0.0542
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0024 0.0024
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0012 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0006 0.0085
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0057 0.0121 0.0121
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0094 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0111 0.0217
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0014 0.0068
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0111 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Echinococcus granulosus g-protein coupled receptor 0.0131 0.032 0.032
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0107 0.0181
Brugia malayi nuclear receptor NHR-88 0.003 0.005 0.0098
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.005 0.005
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Brugia malayi Uncoordinated protein 44 0.0015 0.0012 0.0022
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0014 0.0161
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000046697 0.0000091722
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0018 0.003
Loa Loa (eye worm) inositol-1 0.0074 0.0167 0.0328
Schistosoma mansoni glutamate receptor NMDA 0.025 0.0637 0.108
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Echinococcus multilocularis muscleblind protein 0.0145 0.0358 0.0358
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0017 0.0017 0.0033
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0131 0.032 0.0542
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0046 0.009
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0068 0.0068
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0111 0.0217
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis tyrosine protein kinase HCK 0.0037 0.007 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0077 0.0406
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0062 0.0062
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0035 0.0176
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Brugia malayi Metabotropic glutamate receptor precursor. 0.0016 0.0013 0.0024
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0006 0.0012
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0326 0.084 0.1423
Onchocerca volvulus 0.0038 0.0072 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Leishmania major DNA polymerase kappa, putative 0.0025 0.0038 0.0187
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0129
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0012 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis neuropeptide receptor A26 0.0131 0.032 0.032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0274 0.07 0.1376
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.032 0.032
Echinococcus granulosus FTZ F1 alpha 0.003 0.005 0.005
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0281 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0142 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0077 0.1289
Loa Loa (eye worm) RNA binding protein 0.0066 0.0146 0.0286
Brugia malayi Protein kinase c protein 2 0.0017 0.0017 0.0032
Onchocerca volvulus 0.0016 0.0013 0.0024
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0017 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) glutamate receptor 2 0.0153 0.0377 0.0741
Schistosoma mansoni nocturnin 0.0016 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0077 0.0915
Toxoplasma gondii diacylglycerol kinase, putative 0.0017 0.0015 0.0182
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0008 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0131 0.032 0.0542
Brugia malayi PAS domain containing protein 0.0051 0.0107 0.021
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0017 0.0034
Onchocerca volvulus 0.0127 0.0309 0.0607
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.032 0.032
Brugia malayi carbohydrate phosphorylase 0.0116 0.028 0.055
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0281 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0111 0.0217
Onchocerca volvulus 0.0014 0.0008 0.0015
Onchocerca volvulus 0.0037 0.0068 0.0133
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.005 0.0085
Echinococcus multilocularis sodium and chloride dependent glycine 0.0326 0.084 0.084
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0043 0.0201
Leishmania major C-14 sterol reductase, putative 0.0092 0.0216 0.1082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0088
Onchocerca volvulus Cathepsin L homolog 0.002 0.0024 0.0046
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0055 0.0649
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Echinococcus granulosus protein kinase c eta type 0.0017 0.0015 0.0015
Onchocerca volvulus 0.0024 0.0035 0.0068
Echinococcus granulosus transcription factor Dp 1 0.0087 0.0201 0.0201
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Echinococcus granulosus protein kinase c iota type 0.0017 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Brugia malayi Cytochrome P450 family protein 0.0078 0.0178 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0014 0.0056
Echinococcus multilocularis glutamate receptor NMDA 0.0082 0.0188 0.0188
Schistosoma mansoni sodium/chloride dependent transporter 0.1923 0.5091 0.8629
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0077 0.0406
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.005 0.005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.032 0.0542
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0035 0.0163
Echinococcus granulosus Rac GTPase activating protein 1 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni neuropeptide receptor 0.0131 0.032 0.0542
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni nuclear receptor 0.0014 0.0008 0.0013
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Brugia malayi 6-phosphofructokinase 0.0117 0.0281 0.0552
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0077 0.1289
Schistosoma mansoni tyrosine kinase 0.0019 0.0022 0.0037
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0035 0.0035
Brugia malayi nuclear receptor RXR 0.0014 0.0008 0.0015
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0046 0.0077
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0015 0.0025
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0111 0.0188
Onchocerca volvulus 0.002 0.0024 0.0046
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0006 0.001
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0325 0.0835 0.0835
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068
Schistosoma mansoni diacylglycerol kinase theta 0.0017 0.0015 0.0025
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0024 0.0024
Echinococcus granulosus intermediate filament protein 0.0028 0.0045 0.0045
Schistosoma mansoni growth hormone secretagogue receptor 0.0131 0.032 0.0542
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0017 0.0465
Loa Loa (eye worm) hypothetical protein 0.0064 0.0142 0.0279
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1122 0.2957 0.5809
Brugia malayi hypothetical protein 0.0014 0.0008 0.0015
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.015 0.0369 0.0725
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0111 0.0217
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0077 0.0077
Echinococcus granulosus metabotropic glutamate receptor 5 0.0016 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0008 0.0008
Leishmania major sterol C-24 reductase, putative 0.0048 0.0098 0.0491
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0046 0.0077
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0011 0.002
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0077 0.1289
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0167 0.2312
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0065 0.0065
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0106 0.1259
Onchocerca volvulus 0.0131 0.032 0.0628
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0184 0.0184
Schistosoma mansoni biogenic amine (5HT) receptor 0.0131 0.032 0.0542
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0068 0.0943
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Brugia malayi nuclear hormone receptor 0.003 0.005 0.0098
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0131 0.032 0.0628
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0003 0.0003
Brugia malayi Pleckstrin Homology Domain 0.0017 0.0015 0.0029
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0013 0.0024
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0077 0.1289
Schistosoma mansoni nuclear hormone receptor 0.003 0.005 0.0085
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0014 0.0069
Brugia malayi hypothetical protein 0.0064 0.0142 0.0278
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Onchocerca volvulus 0.0127 0.0309 0.0607
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Echinococcus multilocularis c src tyrosine kinase 0.0012 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Schistosoma mansoni biogenic amine (5HT) receptor 0.0131 0.032 0.0542
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0131 0.032 0.0628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0077 0.1289
Schistosoma mansoni diacylglycerol kinase theta 0.0017 0.0015 0.0025
Onchocerca volvulus 0.002 0.0024 0.0046
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3767 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0023
Echinococcus granulosus sodium and chloride dependent glycine 0.0326 0.084 0.084
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0184 0.0361
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0127 0.0309 0.0524
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.005 0.0098
Loa Loa (eye worm) fibroinase 0.002 0.0024 0.0047
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0014 0.0367
Echinococcus granulosus glycogen phosphorylase 0.0116 0.028 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0117
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Entamoeba histolytica glycogenphosphorylase, putative 0.005 0.0105 0.2827
Loa Loa (eye worm) SRC-1 0.0046 0.0092 0.0182
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0015 0.0025
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Brugia malayi cathepsin L-like precursor 0.0013 0.0006 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0173 0.0859
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0002 0.0002
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Onchocerca volvulus 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0103 0.0245 0.0481
Giardia lamblia GTOR 0.0018 0.0017 0.0136
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0281 0.0476
Toxoplasma gondii cathepsin CPL 0.002 0.0024 0.0283
Brugia malayi sulfakinin receptor protein 0.0131 0.032 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0068 0.033
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0003 0.0064
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0077 0.1289
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0077 0.1289
Echinococcus multilocularis g protein coupled receptor 0.0131 0.032 0.032
Brugia malayi RhoGAP domain containing protein 0.0021 0.0027 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Onchocerca volvulus 0.0326 0.084 0.1649
Loa Loa (eye worm) hypothetical protein 0.0037 0.0069 0.0136
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.065 0.1276
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0111 0.0111
Echinococcus granulosus Diacylglycerol kinase theta 0.0017 0.0015 0.0015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0038 0.0626
Echinococcus multilocularis fmrfamide receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0111 0.0217
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0131 0.032 0.032
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.044 0.6089
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Onchocerca volvulus 0.0131 0.032 0.0628
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Brugia malayi Pre-SET motif family protein 0.0036 0.0065 0.0128
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0377 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0131 0.032 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Brugia malayi steroid hormone receptor 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0014 0.0227
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Echinococcus multilocularis G-protein coupled receptor, putative 0.0131 0.032 0.032
Schistosoma mansoni protein kinase C mu 0.0017 0.0015 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0038 0.0189
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi RhoGEF domain containing protein 0.0017 0.0015 0.0029
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0077 0.1289
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0094 0.0094
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0281 0.1413
Loa Loa (eye worm) RasGEF domain-containing protein 0.0017 0.0015 0.003
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0057 0.0121 0.0121
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0068 0.1143
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0125 0.0629
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0086
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0161
Echinococcus granulosus Ankyrin 0.0016 0.0013 0.0013
Brugia malayi Steroid receptor seven-up type 2 0.003 0.005 0.0098
Leishmania major cysteine peptidase A (CPA) 0.002 0.0024 0.0118
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Brugia malayi G protein-coupled receptor 0.0131 0.032 0.0628
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0043 0.0214
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0014 0.0191
Brugia malayi G-protein coupled receptor 0.0131 0.032 0.0628
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.0646
Echinococcus multilocularis N chimaerin 0.0021 0.0027 0.0027
Echinococcus granulosus nAChR subunit 0.0028 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0098 0.0479
Echinococcus granulosus serotonin transporter 0.1923 0.5091 0.5091
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0043 0.0507
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0017 0.0075
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Schistosoma mansoni hypothetical protein 0.0131 0.032 0.0542
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0035 0.0035
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0646
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.0123 0.1464
Schistosoma mansoni hypothetical protein 0.0703 0.1842 0.3121
Echinococcus granulosus lamin dm0 0.0028 0.0045 0.0045
Onchocerca volvulus 0.0013 0.0006 0.0011
Brugia malayi Dopamine receptor protein 1 0.0131 0.032 0.0628
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0077 0.2574
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0014 0.0027
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0077 0.0406
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0216 0.1072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0036
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0075
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.005 0.0099
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0055 0.1526
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0432 0.0848
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Schistosoma mansoni nAChR subunit 0.0024 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0393 0.0772
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.008 0.0403
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0023 0.0274
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0024 0.0047
Brugia malayi tailless protein 0.0014 0.0008 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0081 0.0081
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.008 0.0185 0.5471
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0033
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0055 0.0646
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0077 0.1289
Mycobacterium leprae Probable lipase LipE 0.0037 0.0068 0.226
Brugia malayi diacylglycerol kinase 0.0017 0.0015 0.0029
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.008 0.0185 0.0185
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0326 0.084 0.084
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0111 0.0111
Schistosoma mansoni cript-related 0.0016 0.0014 0.0023
Brugia malayi hypoxia-induced factor 1 0.0159 0.0393 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0072 0.0072
Onchocerca volvulus 0.0016 0.0014 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Onchocerca volvulus 0.0024 0.0035 0.0068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0111 0.0217
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0094 0.0159
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0022 0.0043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0015 0.003
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0068 0.1143
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0046 0.009
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0142 0.1688
Trypanosoma brucei unspecified product 0.0012 0.0002 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0017 0.0083
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus granulosus tyrosine protein kinase HCK 0.0037 0.007 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Cathepsin L-like precursor 0.0013 0.0006 0.0012
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0008 0.0016
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Schistosoma mansoni synaptojanin 0.0016 0.0014 0.0023
Echinococcus granulosus somatostatin receptor 0.0131 0.032 0.032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Entamoeba histolytica hypothetical protein 0.0024 0.0035 0.094
Echinococcus multilocularis musashi 0.0028 0.0045 0.0045
Echinococcus multilocularis dna polymerase eta 0.0017 0.0017 0.0017
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0035 0.0059
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0013 0.0021
Brugia malayi SRC-1 0.0046 0.0092 0.0181
Schistosoma mansoni lipoxygenase 0.0323 0.0829 0.1405
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.005 0.005
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0017 0.0207
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0219
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0326 0.084 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0092 0.0092
Brugia malayi G-protein coupled receptor 0.0131 0.032 0.0628
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0111 0.0217
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0043 0.0201
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0111 0.0217
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0142 0.0279
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0077 0.0406
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.032 0.032
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus multilocularis nmda type glutamate receptor 0.0098 0.0231 0.0231
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0068 0.0943
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0024 0.028
Echinococcus multilocularis cysteine protease 0.002 0.0024 0.0024
Brugia malayi ORL1-like opioid receptor 0.0131 0.032 0.0628
Schistosoma mansoni protein kinase 0.0019 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0173 0.0432 0.0849
Echinococcus granulosus neuropeptide FF receptor 2 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.005 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0014 0.0161
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0068 0.1143
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus nmda type glutamate receptor 0.0098 0.0231 0.0231
Echinococcus multilocularis protein kinase c epsilon type 0.0017 0.0017 0.0017
Leishmania major hypothetical protein, conserved 0.0037 0.0068 0.0342
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0146 0.0286
Echinococcus granulosus Protein kinase C brain isozyme 0.0017 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0062
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0055 0.147
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0345 0.0677
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0046 0.009
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1923 0.5091 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0008 0.0015
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0024 0.0637
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0077 0.0406
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0142 0.0142
Schistosoma mansoni sodium-dependent amino acid transporter 0.0326 0.084 0.1423
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0012 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0127 0.0309 0.0607
Onchocerca volvulus 0.0326 0.084 0.1649
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0045 0.0089
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0146 0.0146
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0131 0.032 0.032
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Onchocerca volvulus 0.0019 0.0022 0.0043
Brugia malayi hypothetical protein 0.0016 0.0013 0.0024
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.005 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.065 0.8988
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0015 0.0015
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0068 0.0068
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.015 0.0369 0.0625
Echinococcus multilocularis fmrfamide receptor 0.0131 0.032 0.032
Onchocerca volvulus 0.0017 0.0015 0.0029
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0377 0.0639
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Schistosoma mansoni protein kinase C 0.0017 0.0015 0.0025
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0011 0.0021
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0167 0.199
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0072 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0021 0.0027 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0017 0.0274
Echinococcus multilocularis FTZ F1 alpha 0.003 0.005 0.005
Trichomonas vaginalis ABC transporter, putative 0.0011 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0017 0.0088
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0111 0.0111
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0147 0.2462
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0008 0.0015
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0016 0.0013 0.0025
Echinococcus granulosus N chimaerin 0.0021 0.0027 0.0027
Schistosoma mansoni sodium/chloride dependent transporter 0.0327 0.0841 0.1425
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.008 0.0185 0.0929
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0173 0.0431 0.073
Echinococcus granulosus sodium and chloride dependent glycine 0.0326 0.084 0.084
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Serotonin receptor 0.0131 0.032 0.0628
Onchocerca volvulus 0.002 0.0024 0.0046
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0077 0.1289
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0075
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0217
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0015 0.0015
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0111 0.0111
Brugia malayi conserved hypotetical protein 0.0014 0.0008 0.0015
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0006 0.0083
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0049 0.0101 0.1397
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.1013 0.2668 0.5241
Schistosoma mansoni hypothetical protein 0.0064 0.0142 0.024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0106 0.1465
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0326 0.084 0.1423
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0131 0.032 0.032
Echinococcus granulosus microtubule associated protein 2 0.2227 0.59 0.59
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.032 0.0542
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0156
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.032 0.032
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0003 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0024 0.0106
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0024 0.028
Brugia malayi follicle stimulating hormone receptor 0.0378 0.0978 0.192
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0106 0.1262
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0081 0.0081
Echinococcus granulosus tyrosine kinase 0.0019 0.0022 0.0022
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0017 0.0028
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Echinococcus multilocularis serotonin receptor 0.0131 0.032 0.032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0184 0.0184
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0017 0.0015 0.003
Brugia malayi Protein kinase domain containing protein 0.0016 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Serotonin receptor 0.0131 0.032 0.0628
Trypanosoma brucei unspecified product 0.0012 0.0002 0.0011
Onchocerca volvulus 0.0028 0.0046 0.009
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0131 0.032 0.0542
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0125 0.0246
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0077 0.0406
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Schistosoma mansoni DNA polymerase eta 0.0017 0.0017 0.0028
Echinococcus multilocularis transcription factor Dp 1 0.0087 0.0201 0.0201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0077 0.1289
Echinococcus granulosus 7TM GPCR rhodopsin 0.0131 0.032 0.032
Echinococcus granulosus 7tm_1 domain containing protein 0.0131 0.032 0.032
Schistosoma mansoni synaptojanin 0.0016 0.0014 0.0023
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0024 0.0024
Schistosoma mansoni netrin receptor unc5 0.0015 0.0012 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Schistosoma mansoni lamin 0.0028 0.0045 0.0076
Trypanosoma brucei protein kinase, putative 0.0057 0.0123 0.062
Schistosoma mansoni glycogen phosphorylase 0.005 0.0105 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Onchocerca volvulus 0.0064 0.0142 0.0278
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0017 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0111 0.0217
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0167 0.2312
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0131 0.032 0.0542
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0184 0.0362
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0077 0.0406
Echinococcus multilocularis vesicular acetylcholine transporter 0.1122 0.2957 0.2957
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0024
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0146 0.0286
Echinococcus granulosus tachykinin peptides receptor 99D 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.005 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Trypanosoma cruzi C-14 sterol reductase, putative 0.0092 0.0216 0.1072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.005 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0326 0.084 1
Mycobacterium leprae putative cytochrome p450 0.004 0.0077 0.2574
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0035 0.0068
Echinococcus multilocularis glutamate receptor 2 0.0169 0.0419 0.0419
Echinococcus granulosus fmrfamide receptor 0.0131 0.032 0.032
Onchocerca volvulus Cathepsin L homolog 0.002 0.0024 0.0046
Trichomonas vaginalis glycogen phosphorylase, putative 0.0116 0.028 0.3877
Loa Loa (eye worm) raf kinase 0.0479 0.1246 0.2447
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0014 0.0014
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.005 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.005 0.0085
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.0298 0.0765 0.1296
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1923 0.5091 0.8629
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0014 0.0014
Onchocerca volvulus 0.0326 0.084 0.1649
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0281 0.0552
Echinococcus granulosus dna polymerase kappa 0.0049 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0131 0.032 0.032
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0012 0.0002 0.0002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0092 0.0092
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.005 0.005
Schistosoma mansoni ap endonuclease 0.008 0.0185 0.0313
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) solute carrier family 6 member 4 0.1923 0.5091 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Loa Loa (eye worm) TK protein kinase 0.0037 0.007 0.0137
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Leishmania major cytochrome p450-like protein 0.004 0.0077 0.0385
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0019 0.0022 0.0043
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Entamoeba histolytica protein kinase, putative 0.0037 0.007 0.188
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0024 0.0328
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0146 0.0285
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.005 0.0098
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0055 0.0649
Schistosoma mansoni hypothetical protein 0.0703 0.1842 0.3121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus granulosus tyrosine protein kinase Lyn 0.0046 0.0094 0.0094
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0055 0.0646
Schistosoma mansoni tyrosine kinase 0.0012 0.0003 0.0004
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0016 0.0013 0.0025
Brugia malayi larval opioid receptor 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Loa Loa (eye worm) cytochrome P450 0.004 0.0077 0.0151
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0092 0.0092
Echinococcus multilocularis lamin b receptor 0.0092 0.0216 0.0216
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0014 0.0056
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0281 0.4727
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0131 0.032 0.0628
Brugia malayi Muscleblind-like protein 0.0145 0.0358 0.0702
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0131 0.032 0.032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.005 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0092 0.0092
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.008 0.0185 0.0917
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0068 0.0133
Echinococcus granulosus nAChR subunit 0.0053 0.0111 0.0111
Onchocerca volvulus 0.0053 0.0111 0.0217
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0111 0.0111
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica diacylglycerol kinase, putative 0.0017 0.0015 0.0406
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Loa Loa (eye worm) hypothetical protein 0.0254 0.0646 0.1268
Schistosoma mansoni rac gtpase activating protein 0.0017 0.0015 0.0025
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0012 0.0023
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.005 0.0098
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0035 0.0035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0035 0.0068
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0017 0.0086
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0006 0.016
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.032 0.032
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0024 0.028
Schistosoma mansoni amine GPCR 0.0131 0.032 0.0542
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0006 0.0069
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0045 0.0088
Echinococcus multilocularis dro:myosuppressin receptor 0.0131 0.032 0.032
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.015 0.0369 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0016 0.0013 0.0013
Brugia malayi hypothetical protein 0.0024 0.0035 0.0068
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Onchocerca volvulus 0.0017 0.0015 0.0029
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0077 0.0406
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Loa Loa (eye worm) beta-lactamase 0.0037 0.0068 0.0134
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.032 0.0629
Schistosoma mansoni adenoreceptor 0.0131 0.032 0.0542
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.005 0.0098
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.008 0.0185 0.2197
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0021 0.0027 0.0027
Toxoplasma gondii ABC1 family protein 0.0037 0.0068 0.0812
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0014 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Echinococcus granulosus neuropeptide receptor 0.0131 0.032 0.032
Schistosoma mansoni coup transcription factor 0.003 0.005 0.0085
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.032 0.0629
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0075
Echinococcus granulosus glutamate receptor 2 0.0169 0.0419 0.0419
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.008 0.0185 0.0928
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni ATP-binding cassette transporter 0.0153 0.0378 0.0639
Brugia malayi RNA binding protein 0.0066 0.0146 0.0285
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0085 0.0166
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0017 0.0088
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0281 0.1414
Schistosoma mansoni biogenic amine receptor 0.0131 0.032 0.0542
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0024 0.004
Brugia malayi mbt repeat family protein 0.0046 0.0094 0.0184
Onchocerca volvulus Cathepsin F homolog 0.002 0.0024 0.0046
Echinococcus multilocularis neuropeptide receptor 0.0131 0.032 0.032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0841
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0646 0.1268
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Brugia malayi exodeoxyribonuclease III family protein 0.008 0.0185 0.0362
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0064 0.0108
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.032 0.032
Echinococcus granulosus synaptojanin 1 0.0016 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0017 0.0086
Schistosoma mansoni histamine h1 receptor 0.0131 0.032 0.0542
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0035 0.0069
Echinococcus multilocularis tyrosine protein kinase Abl 0.0012 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Echinococcus multilocularis g-protein coupled receptor 0.0131 0.032 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0012 0.0002 0.0002
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.165
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0111 0.0217
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0131 0.032 0.0628
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0142 0.1688
Trypanosoma cruzi DNA polymerase kappa, putative 0.0049 0.0101 0.0496
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0035 0.0069
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0038 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Brugia malayi Death domain containing protein 0.0015 0.0012 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.032 0.0542
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.0111 0.0217
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0081 0.0081
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0106 0.0106
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0022 0.0043
Leishmania major extracellular receptor, putative 0.0016 0.0013 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0416 0.5757
Brugia malayi nuclear hormone receptor 0.0014 0.0008 0.0015
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0323 0.0829 0.0829
Echinococcus granulosus protein kinase c epsilon type 0.0017 0.0017 0.0017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0326 0.084 0.1423
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0056
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0068 0.1143
Brugia malayi putative neuropeptide receptor 0.0131 0.032 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0125 0.2668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi ecdysteroid receptor 0.003 0.005 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Echinococcus multilocularis NMDA receptor 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi hypothetical protein 0.0064 0.0142 0.0278
Echinococcus granulosus glutamate receptor 2 0.0112 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.008 0.0184 0.0362
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0077 0.0406
Trichomonas vaginalis set domain proteins, putative 0.0283 0.0723 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Brugia malayi Pre-SET motif family protein 0.0248 0.0632 0.124
Echinococcus granulosus vesicular acetylcholine transporter 0.1122 0.2957 0.2957
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0084
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0326 0.084 1
Brugia malayi Glutamate receptor 1 precursor 0.0153 0.0377 0.074
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0111 0.0111
Echinococcus granulosus lamin 0.0028 0.0045 0.0045
Leishmania major cathepsin L-like protease 0.0076 0.0173 0.087
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0006 0.0083
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0014 0.0367
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0008 0.0015
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0043 0.0504
Toxoplasma gondii hypothetical protein 0.0326 0.084 1
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0011 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0345 0.0584
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0011 0.0127
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.005 0.005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0011 0.0129
Brugia malayi TAR-binding protein 0.0066 0.0146 0.0285
Leishmania major protein kinase, putative 0.0019 0.0021 0.0105
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Plasmodium falciparum amino acid transporter, putative 0.0326 0.084 1
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi nuclear receptor NHR-67 0.0014 0.0008 0.0015
Brugia malayi nuclear receptor RXR 0.0016 0.0013 0.0024
Schistosoma mansoni zinc finger protein 0.0014 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0 0.0004
Schistosoma mansoni opsin-like receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0015 0.003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.008 0.0185 0.0185
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0026 0.0117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0077 0.1289
Entamoeba histolytica diacylglycerol kinase, putative 0.0017 0.0015 0.0406
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0111 0.0111
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0017 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.005 0.0098
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0068 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0035 0.0059
Onchocerca volvulus 0.1923 0.5091 1
Loa Loa (eye worm) hypothetical protein 0.0172 0.0429 0.0842
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0047
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0111 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Echinococcus multilocularis sodium and chloride dependent glycine 0.0326 0.084 0.084
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0345 0.0345
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0345 0.0676
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0014 0.0023
Echinococcus multilocularis lamin 0.0028 0.0045 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0281 0.3889
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0017 0.0017
Schistosoma mansoni Lamin B receptor (ERG24) 0.0092 0.0216 0.0365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.015 0.0369 0.1854
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0014 0.0014
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0057 0.0121 0.0121
Toxoplasma gondii hypothetical protein 0.0326 0.084 1
Schistosoma mansoni nAChR subunit 0.0024 0.0035 0.0059
Entamoeba histolytica glycogen phosphorylase, putative 0.005 0.0105 0.2827
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0377 0.0639
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0567 0.1479 0.2905
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.032 0.032
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0501 0.0501
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Entamoeba histolytica glycogen phosphorylase, putative 0.0116 0.028 0.7597
Loa Loa (eye worm) steroid hormone receptor 0.003 0.005 0.0099
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0125 0.0246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Echinococcus multilocularis nAChR subunit 0.0028 0.0046 0.0046
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0077 0.0406
Onchocerca volvulus 0.0028 0.0045 0.0088
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0179
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.005 0.005
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.005 0.005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1845
Onchocerca volvulus 0.0053 0.0111 0.0217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0184 0.0184
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0031 0.0423
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0017 0.0017 0.0032
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0 0.0001
Schistosoma mansoni lamin 0.0028 0.0045 0.0076
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0014 0.0014
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0068 0.0134
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0006 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.032 0.032
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0068 0.0943
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Schistosoma mansoni metabotropic glutamate receptor 0.0016 0.0013 0.0021
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0095 0.3034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0064 0.0064
Echinococcus granulosus g protein coupled receptor 0.0131 0.032 0.032
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0014 0.0056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0378 0.0978 0.192
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0017 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0014 0.0069
Echinococcus multilocularis nAChR subunit 0.0053 0.0111 0.0111
Brugia malayi protein kinase C II. 0.0017 0.0017 0.0032
Onchocerca volvulus 0.0037 0.0068 0.0133
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0281 0.1403
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0068 0.0809
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.005 0.0098
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0077 0.0406
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Brugia malayi Latrophilin receptor protein 2 0.008 0.0184 0.0361
Onchocerca volvulus 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.0111 0.0111
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0101 0.0508
Schistosoma mansoni hypothetical protein 0.0035 0.0064 0.0108
Loa Loa (eye worm) ctsf protein 0.002 0.0024 0.0047
Echinococcus multilocularis glycogen phosphorylase 0.0116 0.028 0.028
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0002 0.0002
Loa Loa (eye worm) cysteine protease 0.002 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.0123 0.0607
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0326 0.084 0.165
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0142 0.0279
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0014 0.0161
Brugia malayi beta-lactamase family protein 0.0037 0.0068 0.0133
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0014 0.0367
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0758 0.1988 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0326 0.084 0.084
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.032 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.005 0.0099
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0008 0.0008
Plasmodium vivax amine transporter, putative 0.0326 0.084 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0753
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0015 0.0175
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Brugia malayi CCR4 0.0016 0.0014 0.0027
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0017 0.0017 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0 0.0004
Brugia malayi beta-lactamase family protein 0.0037 0.0068 0.0133
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0326 0.084 0.084
Onchocerca volvulus 0.0036 0.0065 0.0128
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0008 0.0015
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0014 0.0014
Leishmania major protein kinase, putative 0.0014 0.0008 0.0036
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0167 0.2312
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.032 0.032
Leishmania major DNA polymerase eta, putative 0.0017 0.0017 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.008 0.0185 0.0363
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0111 0.0111
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.008 0.0185 1
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0011 0.0018
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0326 0.084 0.1423
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0065 0.011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.005 0.0098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.008 0.0185 0.3104
Echinococcus multilocularis neuropeptide receptor 0.0131 0.032 0.032
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0131 0.032 0.0629
Brugia malayi hypothetical protein 0.0017 0.0017 0.0033
Brugia malayi hypothetical protein 0.0172 0.0429 0.0841
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0014 0.0056
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0077 0.0406
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0077 0.0406
Onchocerca volvulus Bile acid receptor homolog 0.003 0.005 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0377 0.0377
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Schistosoma mansoni tyrosine kinase 0.0012 0.0003 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0178 0.0349
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0 0.0004
Brugia malayi ecdysone receptor 0.0014 0.0008 0.0015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0131 0.032 0.032
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0012 0.0012
Brugia malayi Cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0037 0.0068 0.1143
Onchocerca volvulus 0.0131 0.032 0.0628
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0083
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0111 0.0217
Schistosoma mansoni hypothetical protein 0.005 0.0105 0.0177
Echinococcus multilocularis Diacylglycerol kinase theta 0.0017 0.0015 0.0015
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0098 0.0479
Brugia malayi intracellular kinase 0.0057 0.0123 0.0241
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0017 0.0075
Loa Loa (eye worm) hypothetical protein 0.0145 0.0358 0.0703
Brugia malayi putative neuropeptide receptor NPR1 0.0131 0.032 0.0628
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0012 0.0002 0.0002
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.0123 0.0123
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0123 0.4105
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0017 0.0017
Echinococcus multilocularis microtubule associated protein 2 0.2227 0.59 0.59
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0288 0.0567
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Onchocerca volvulus 0.0016 0.0014 0.0027
Leishmania major hypothetical protein, conserved 0.0027 0.0043 0.0213
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1845
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0241
Brugia malayi hypothetical protein 0.0027 0.0043 0.0083
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0234 0.0595 1
Trichomonas vaginalis ap endonuclease, putative 0.008 0.0185 0.2555
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0077 0.0406
Schistosoma mansoni hypothetical protein 0.0173 0.0432 0.0732
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0072 0.0159
Schistosoma mansoni alpha-1 adrenergic receptor 0.0131 0.032 0.0542
Echinococcus granulosus bloom syndrome protein 0.0023 0.0031 0.0031
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0095 0.2561
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Echinococcus multilocularis glycogen phosphorylase 0.0116 0.028 0.028
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0012
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0024 0.0047
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0125 0.0617
Plasmodium vivax SET domain protein, putative 0.0036 0.0065 0.0776
Echinococcus multilocularis neuropeptide FF receptor 2 0.0131 0.032 0.032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0064 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0024 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0483
Brugia malayi Glutamate receptor 2 precursor 0.0153 0.0377 0.074
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0014 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0024 0.0328
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Onchocerca volvulus 0.002 0.0024 0.0046
Schistosoma mansoni protein kinase C mu 0.0017 0.0017 0.0028
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Brugia malayi Abnormal catecholamine distribution protein 1 0.0567 0.1479 0.2904
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0326 0.084 0.1649
Loa Loa (eye worm) norepinephrine transporter 0.1923 0.5091 1
Echinococcus multilocularis glutamate receptor 2 0.0112 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0017 0.0017
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0164
Echinococcus multilocularis nmda type glutamate receptor 0.0138 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0014 0.0367
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0031 0.006
Echinococcus granulosus GPCR family 2 0.008 0.0184 0.0184
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0055 0.0753
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Loa Loa (eye worm) glycogen phosphorylase 0.0116 0.028 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.005 0.0098
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0758 0.1988 0.3905
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0014 0.0191
Onchocerca volvulus 0.0046 0.0094 0.0184
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.005 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.032 0.032
Treponema pallidum sodium- and chloride- dependent transporter 0.1923 0.5091 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0094 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0077 0.1289
Loa Loa (eye worm) DR-78 0.0014 0.0008 0.0016
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0106 0.1262
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0099
Leishmania major cathepsin L-like protease 0.002 0.0024 0.0118
Echinococcus granulosus death domain containing protein 0.0015 0.0012 0.0012
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0031 0.0423
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0035 0.0035
Echinococcus granulosus cathepsin l1 0.002 0.0024 0.0024
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0014 0.0068
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0156 0.0771
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0003 0.0013
Brugia malayi MH2 domain containing protein 0.0119 0.0288 0.0566
Trypanosoma brucei DNA polymerase IV, putative 0.0049 0.0101 0.0508
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus Glycosyl transferase family 35 0.0116 0.028 0.028
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0055 0.0649
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0008 0.0013
Onchocerca volvulus 0.0017 0.0015 0.0029
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0014 0.0069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0014 0.0027
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0358 0.0358
Brugia malayi neuropeptide F receptor 0.0131 0.032 0.0628
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0131 0.032 0.0542
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0065 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0014 0.0191
Brugia malayi Tyrosine-protein kinase abl-1 0.0012 0.0003 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0345 0.0345
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0092 0.0092
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0829
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0017 0.0017 0.0017
Trypanosoma brucei unspecified product 0.0041 0.008 0.0403
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0142 0.0142
Brugia malayi protein-tyrosine kinase 0.0042 0.0081 0.0159
Schistosoma mansoni single-minded 0.0051 0.0107 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.005 0.0098
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0131 0.032 0.0542
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0003 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0131 0.032 0.0628
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0016 0.0013 0.0024
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0068 0.0115
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0075
Schistosoma mansoni rab6-interacting 0.0064 0.0142 0.024
Brugia malayi metabotropic glutamate receptor type 2 0.0016 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0069
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0077 0.0374
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.0123 0.0123
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0008 0.0013
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0068 0.226
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0369 0.1856
Trichomonas vaginalis taga, putative 0.0011 0 0.0004
Brugia malayi cytochrome P450 0.004 0.0077 0.015
Brugia malayi GnHR receptor homolog 0.0131 0.032 0.0628
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.044 0.6089
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0035 0.0069
Echinococcus granulosus biogenic amine 5HT receptor 0.0131 0.032 0.032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Echinococcus multilocularis G protein coupled receptor 139 0.0131 0.032 0.032
Schistosoma mansoni hypothetical protein 0.008 0.0184 0.0312
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.1727
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0035 0.0035
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.0123 0.1464
Onchocerca volvulus 0.0064 0.0142 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0024 0.0328
Giardia lamblia Kinase, CMGC GSK 0.0057 0.0123 0.4105
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0014 0.0069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Echinococcus multilocularis geminin 0.0703 0.1842 0.1842
Loa Loa (eye worm) hypothetical protein 0.0131 0.032 0.0629
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.005 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0173 0.0871
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0131 0.032 0.032
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0008 0.0008
Echinococcus granulosus single minded 2 0.0042 0.0081 0.0081
Schistosoma mansoni intermediate filament proteins 0.0028 0.0045 0.0076
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.009
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0094 0.0094
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0017 0.0086
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.165
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0008 0.0025
Leishmania major C-8 sterol isomerase-like protein 0.0758 0.1988 1
Brugia malayi hypothetical protein 0.0326 0.084 0.1649
Onchocerca volvulus 0.0131 0.032 0.0628
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0081 0.0081
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0027 0.0045
Brugia malayi Ras association domain family 1 isoform A 0.0017 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0014 0.0027
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0248 0.0632 0.1241
Onchocerca volvulus 0.0024 0.0035 0.0068
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0017 0.0017 0.0033
Echinococcus granulosus lamin b receptor 0.0092 0.0216 0.0216
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Schistosoma mansoni glycogen phosphorylase 0.0116 0.028 0.0475
Brugia malayi hypothetical protein 0.0131 0.032 0.0628
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0416 0.0817
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0092 0.0092
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0169 0.0419 0.0419
Brugia malayi hypothetical protein 0.0014 0.0008 0.0015
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0015 0.0248
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0014 0.0161
Echinococcus granulosus unc 13 munc13 0.0017 0.0015 0.0015
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0008 0.0008
Echinococcus granulosus muscleblind protein 0.0145 0.0358 0.0358
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.005 0.0105 0.1754
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0072 0.0072
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0068 0.1143
Brugia malayi Cation transporter family protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0111 0.0217
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0094 0.0159
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.008 0.0185 0.6413
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Schistosoma mansoni rab6-interacting 0.0064 0.0142 0.024
Brugia malayi Cathepsin L-like precursor 0.002 0.0024 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0111 0.0217
Echinococcus granulosus allatostatin A receptor 0.0131 0.032 0.032
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0035 0.0035
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0014 0.0068
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0326 0.084 0.084
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0281 0.0552
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0146 0.0246
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0173 0.0431 0.0431
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0326 0.084 0.1649
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0069 0.0349
Echinococcus granulosus geminin 0.0703 0.1842 0.1842
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0068 0.0115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0068 0.0933
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0057 0.0121 0.0121
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0024 0.0328
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0167 0.0839
Loa Loa (eye worm) glutamate receptor 1 0.0153 0.0377 0.0741
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0022 0.0044
Echinococcus granulosus RUN 0.0064 0.0142 0.0142
Schistosoma mansoni polycystin 1-related 0.0064 0.0142 0.024
Onchocerca volvulus 0.0131 0.032 0.0628
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0111 0.0217
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0134
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.0123 0.1467
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0003
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0 0.0003
Brugia malayi nuclear receptor NHR-88 0.0014 0.0008 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0068 0.1143
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0015 0.0062
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0014 0.0069
Echinococcus granulosus c src tyrosine kinase 0.0012 0.0003 0.0003
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0131 0.032 0.0628
Loa Loa (eye worm) hypothetical protein 0.1923 0.5091 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0077 0.1289
Onchocerca volvulus 0.0283 0.0724 0.1422
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0008 0.0013
Giardia lamblia Glycogen phosphorylase 0.0116 0.028 1
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0169 0.0419 0.0419
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0046 0.0077
Schistosoma mansoni loxhd1 0.0064 0.0142 0.024
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0014 0.0027
Echinococcus multilocularis orexin receptor type 2 0.0131 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0217
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0014 0.0056
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0169 0.0419 0.0419
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0027
Schistosoma mansoni nAChR subunit 0.0053 0.0111 0.0187
Echinococcus multilocularis protein kinase shaggy 0.0057 0.0123 0.0123
Brugia malayi Doublecortin family protein 0.0064 0.0142 0.0278
Trichomonas vaginalis abcb9, putative 0.0011 0 0.0004
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0025
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0068

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Inhibition of capsaicin-induced flinching in rat at 10 mg/kg, po up to 8 hrs ChEMBL. 17585751
AUC (ADMET) = 1200 ng.hr/ml AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751
AUC (ADMET) = 3100 ng.hr/ml AUC (0-inf) in Sprague-Dawley rat at 5 mg/kg, po up to 8 hrs ChEMBL. 17585751
CL (ADMET) = 0.8 L/hr.Kg Clearance in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751
CL (ADMET) = 400 ml/hr.kg Clearance in monkey at 1 mg/kg, iv ChEMBL. 17585751
CL (ADMET) = 830 ml/hr.kg Clearance in Sprague-Dawley rat at 1 mg/kg, iv after 72 hrs ChEMBL. 17585751
CL (ADMET) = 2400 ml/hr.kg Clearance in dog at 1 mg/kg, iv ChEMBL. 17585751
Cp (ADMET) = 70 ng/ml Plasma concentration in rat model of CFA-induced inflammation ChEMBL. 17585751
Cp (ADMET) = 128 ng/ml Plasma concentration in rat with capsaicin-evoked paw flinching ChEMBL. 17585751
ED50 (functional) = 1.9 mg kg-1 Suppresion of capsaicin-evoked paw flinching in orally dosed rat ChEMBL. 17585751
F (ADMET) = 12 % Oral bioavailability in monkey at 3 mg/kg ChEMBL. 17585751
F (ADMET) = 51 % Oral bioavailability in Sprague-Dawley rat at 5 mg/kg ChEMBL. 17585751
F (ADMET) = 83 % Oral bioavailability in dog at 3 mg/kg ChEMBL. 17585751
IC50 (binding) = 2 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as acid-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 2 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as acid-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 3.7 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as capsaicin-induced Ca2+ influx ChEMBL. 17585751
IC50 (binding) = 3.7 nM Inhibition of rat TRPV1 expressed in CHO cells assessed as capsaicin-induced Ca2+ influx ChEMBL. 17585751
MED (functional) = 1 mg kg-1 Reduction of thermal hyperalgesia in rat model of CFA-induced inflammation in assessed as minimum effective dose ChEMBL. 17585751
Solubility = 7 ug ml-1 Solubility in PBS ChEMBL. 17585751
Solubility = 64 ug ml-1 Solubility in SIF ChEMBL. 17585751
Solubility >= 200 ug ml-1 Solubility in 0.01N HCl ChEMBL. 17585751
t1/2 (ADMET) = 2.7 hr Half life in Sprague-Dawley rat at 1 mg/kg, iv ChEMBL. 17585751
t1/2 (ADMET) = 2.7 hr Half life in dog at 1 mg/kg, iv ChEMBL. 17585751
t1/2 (ADMET) = 3.2 hr Half life in monkey at 1 mg/kg, iv ChEMBL. 17585751
t1/2 (ADMET) = 3.8 hr Half life in Sprague-Dawley rat at 1 mg/kg, iv after 72 hrs ChEMBL. 17585751
Vss (ADMET) = 2.8 L/Kg Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv up to 6 hrs ChEMBL. 17585751
Vss (ADMET) = 900 ml/kg Volume of distribution at steady state in monkey at 1 mg/kg, iv ChEMBL. 17585751
Vss (ADMET) = 2600 ml/kg Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv after 72 hrs ChEMBL. 17585751
Vss (ADMET) = 4000 ml/kg Volume of distribution at steady state in dog at 1 mg/kg, iv ChEMBL. 17585751

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.