Detailed information for compound 566158

Basic information

Technical information
  • TDR Targets ID: 566158
  • Name: 2-amino-4-(butylsulfonimidoyl)butanoic acid
  • MW: 222.305 | Formula: C8H18N2O3S
  • H donors: 2 H acceptors: 3 LogP: -1.1 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCS(=O)(=N)CCC(C(=O)O)N
  • InChi: 1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)
  • InChiKey: KJQFBVYMGADDTQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-azanyl-4-(butylsulfonimidoyl)butanoic acid
  • 2-amino-4-(butylsulfonimidoyl)butyric acid
  • Buthionine Sulfoximine
  • 71765-30-5
  • 5072-26-4
  • 19176_FLUKA
  • DL-Buthionine-sulfoximine
  • NCI60_002827
  • EU-0100231
  • Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-
  • Buthionine-S,R-sulfoximine, L-
  • L-Buthionine (SR)-sulfoximine
  • L-Buthionine-(S,R)-sulfoximine
  • NCGC00093696-02
  • 2-Amino-4-(S-butylsulfonimidoyl)butanoic acid
  • BRN 2367136
  • Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-
  • Buthione sulfoximine
  • Buthionine sulfoxamine
  • Buthionine sulphoximine
  • Buthionine-S,R-sulfoximine
  • Butionine sulfoximine
  • NSC 326231
  • NSC 381100
  • Sulfoximine, S-(3-amino-3-carboxypropyl)-S-butyl-
  • BSPBio_002464
  • Lopac0_000231
  • 71765-30-5 (DELETED)
  • AIDS-026783
  • AIDS026783
  • DL-Buthionine-S,R-sulfoximine
  • B2640_SIGMA
  • C04543
  • S-Butyl-DL-homocysteine-[S,R]-sulfoximine
  • ST5307007
  • L-Buthionine-(S,R)-sulphoximine
  • SPECTRUM1505108
  • BSO
  • L-Buthionine sulfoximine
  • NSC326231
  • NSC381100
  • 2-azaniumyl-4-(butylsulfonimidoyl)butanoate
  • 2-ammonio-4-(butylsulfonimidoyl)butanoate
  • 2-ammonio-4-(butylsulfonimidoyl)butyrate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Plasmodium falciparum gamma-glutamylcysteine synthetase Curated by TDR Targets References
Leishmania major trypanothione reductase Curated by TDR Targets References
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium falciparum gamma-glutamylcysteine synthetase Get druggable targets OG5_128698 All targets in OG5_128698
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus glutamate cysteine ligase catalytic subunit Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis glutamate-cysteine ligase catalytic subunit, putative Get druggable targets OG5_128698 All targets in OG5_128698
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium knowlesi gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K01919 glutamate--cysteine ligase [EC6.3.2.2], putative Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii gamma-glutamylcysteine synthetase-related Get druggable targets OG5_128698 All targets in OG5_128698
Leishmania major gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Schistosoma mansoni glutamate-cysteine ligase Get druggable targets OG5_128698 All targets in OG5_128698
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gamma-glutamylcysteine synthetase Get druggable targets OG5_128698 All targets in OG5_128698
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis glutamate cysteine ligase, catalytic subunit Get druggable targets OG5_128698 All targets in OG5_128698
Giardia lamblia Glutamate-cysteine ligase Get druggable targets OG5_128698 All targets in OG5_128698
Brugia malayi glutamate--cysteine ligase Get druggable targets OG5_128698 All targets in OG5_128698
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei gamma-glutamylcysteine synthetase Get druggable targets OG5_128698 All targets in OG5_128698
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum gamma-glutamylcysteine synthetase Get druggable targets OG5_128698 All targets in OG5_128698
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) glutamate-cysteine ligase Get druggable targets OG5_128698 All targets in OG5_128698
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae GSH1 (YJL101C) Get druggable targets OG5_128698 All targets in OG5_128698
Candida albicans similar to S. cerevisiae GSH1 (YJL101C) Get druggable targets OG5_128698 All targets in OG5_128698
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii glutamate-cysteine ligase, catalytic subunit domain-containing protein Get druggable targets OG5_128698 All targets in OG5_128698
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania donovani gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva gamma-glutamylcysteine synthetase, putative Get druggable targets OG5_128698 All targets in OG5_128698
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast trypanothione reductase 491 aa 551 aa 23.4 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0067 0.0652
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0105 0.0051 0.2859
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0012 0.0327
Trichomonas vaginalis penicillin-binding protein, putative 0.0621 0.0356 0.3471
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0063 0.0027 0.0028
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0002 0.0048
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0095 0.0046 0.0446
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0036 0.1044
Schistosoma mansoni aldehyde dehydrogenase 0.0216 0.0117 0.0122
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0025 0.0004 0.0038
Echinococcus granulosus GPCR family 2 0.0456 0.0258 0.027
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0064 0.0027 0.0752
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0019 0 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Brugia malayi RNA binding protein 0.0307 0.0171 0.1666
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0025 0.0245
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Schistosoma mansoni zinc finger protein 0.0045 0.0016 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0055 0.0022 0.0609
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Onchocerca volvulus 0.0061 0.0026 0.0308
Toxoplasma gondii thioredoxin reductase 0.0185 0.0099 0.2777
Schistosoma mansoni amine GPCR 0.0061 0.0026 0.0027
Brugia malayi Patched protein homolog 1 0.0018 0 0.0001
Trichomonas vaginalis adenylate cyclase type, putative 0.0025 0.0004 0.0038
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0004 0.0108
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0038 0.0012 0.0012
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.0176 0.511
Onchocerca volvulus 0.0061 0.0026 0.0308
Schistosoma mansoni hypothetical protein 0.0061 0.0025 0.0026
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0002 0.0132
Brugia malayi Pre-SET motif family protein 0.0181 0.0096 0.0939
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Echinococcus granulosus peregrin 0.0044 0.0015 0.0016
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0063 0.0027 0.0027
Trichomonas vaginalis esterase, putative 0.0621 0.0356 0.3471
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.0098
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0211 0.0114 0.0487
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0095 0.0046 0.0446
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0476 0.027 0.76
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0055 0.0022 0.0093
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0141 0.0073 0.2029
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0037 0.1038
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0002 0.0046
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0007 0.0181
Onchocerca volvulus 0.0026 0.0005 0.0059
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0067 0.0029 0.0279
Leishmania major cyclic nucleotide-binding protein-like protein 0.0038 0.0012 0.0316
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0011 0.0307
Schistosoma mansoni topbp1 0.003 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0018 0.0073
Echinococcus multilocularis inositol monophosphatase 1 0.016 0.0084 0.0084
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0033 0.0926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0064 0.0027 0.0266
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0133 0.0068 0.0659
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0081 0.0037 0.1028
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0002 0.0002
Trypanosoma cruzi ISWI complex protein 0.0045 0.0016 0.0445
Schistosoma mansoni neuropeptide receptor 0.0266 0.0146 0.0153
Echinococcus multilocularis nibrin 0.003 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0035 0.001 0.0271
Treponema pallidum fructose-bisphosphate aldolase 0.0315 0.0176 0.9799
Brugia malayi isocitrate dehydrogenase 0.0021 0.0002 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0005 0.0138
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0088 0.0042 0.1167
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0095 0.0046 0.0446
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0055 0.0022 0.0609
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 1
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0038 0.0012 0.0327
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0154 0.008 0.2249
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0045 0.0016 0.0016
Echinococcus granulosus snurportin 1 0.1745 0.1019 0.1064
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0027 0.0264
Brugia malayi Bromodomain containing protein 0.012 0.006 0.0585
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.016 0.0084 0.4616
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0004 0.0108
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0055 0.0022 0.0093
Echinococcus granulosus chromobox protein 2 0.0026 0.0005 0.0005
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0002 0.0069
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0016 0.0017
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0064 0.0027 0.0763
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0004 0.0038
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.013 0.0066 0.1851
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0026 0.0027
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0095 0.0046 0.0048
Mycobacterium ulcerans hypothetical protein 0.0038 0.0012 0.0317
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0042 0.0042
Trichomonas vaginalis adenylate cyclase type III, putative 0.0025 0.0004 0.0038
Schistosoma mansoni neuropeptide receptor 0.0061 0.0026 0.0027
Schistosoma mansoni retinoic acid receptor RXR 0.0095 0.0046 0.0048
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus multilocularis ferritin 0.0021 0.0002 0.0002
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.013 0.0066 0.1851
Echinococcus granulosus sex peptide receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0067 0.0029 0.0279
Onchocerca volvulus 0.0026 0.0005 0.0059
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0066 0.0028 0.0028
Onchocerca volvulus 0.0094 0.0045 0.0537
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Trichomonas vaginalis Heterochromatin protein, putative 0.0026 0.0005 0.0048
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0067 0.0029 0.003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0015 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0026 0.0027
Echinococcus multilocularis thyroid hormone receptor alpha 0.0351 0.0196 0.0196
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0038 0.0012 0.0326
Brugia malayi follicle stimulating hormone receptor 0.0339 0.019 0.185
Trichomonas vaginalis DNA polymerase eta, putative 0.0081 0.0037 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1549 0.0904 0.0904
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0095 0.0046 0.0446
Loa Loa (eye worm) thioredoxin reductase 0.0185 0.0099 0.0964
Brugia malayi nuclear receptor NHR-88 0.0095 0.0046 0.0446
Echinococcus granulosus serotonin receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Brugia malayi Patched related family protein 10 0.0018 0 0.0001
Plasmodium vivax hypothetical protein, conserved 0.003 0.0007 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0271 0.0149 0.1458
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0016 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0307 0.0171 0.0178
Echinococcus granulosus allatostatin A receptor 0.0061 0.0026 0.0027
Onchocerca volvulus Cathepsin F homolog 0.0035 0.001 0.0121
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0043 0.0015 0.0015
Echinococcus multilocularis chromobox protein 1 0.0161 0.0085 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.018 0.0095 0.2681
Plasmodium falciparum flap endonuclease 1 0.0019 0 0.0023
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.016 0.0084 0.2354
Onchocerca volvulus 0.0095 0.0046 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Echinococcus granulosus cGMP dependent protein kinase 0.0038 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0002 0.0003
Brugia malayi Cathepsin L-like precursor 0.0023 0.0003 0.0031
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.001 0.0287
Leishmania major protein kinase, putative 0.0038 0.0012 0.032
Loa Loa (eye worm) glutathione reductase 0.0185 0.0099 0.0964
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0037 0.0038
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0011 0.0105
Leishmania major cathepsin L-like protease 0.0035 0.001 0.0271
Echinococcus granulosus g protein coupled receptor 0.0061 0.0026 0.0027
Plasmodium falciparum glutathione reductase 0.0064 0.0027 0.1523
Leishmania major DNA polymerase kappa, putative 0.0081 0.0037 0.1027
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0026 0.0026
Echinococcus granulosus lamin 0.0137 0.007 0.0073
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0225 0.0122 0.3439
Brugia malayi Inositol-1 0.016 0.0084 0.0817
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Brugia malayi PHD-finger family protein 0.0084 0.0039 0.0383
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0016 0.0017
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0055 0.0022 0.0023
Schistosoma mansoni glutaminase 0.0562 0.0321 0.0335
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0189 0.0101 0.2821
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0038 0.0012 0.0326
Brugia malayi Ets-domain containing protein 0.0047 0.0017 0.0166
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0055 0.0022 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0055 0.0022 0.0619
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0026 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0019 0.0187
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0074 0.0033 0.0926
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0026 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0038 0.0012 0.0048
Brugia malayi Fli-1 protein 0.0142 0.0073 0.0716
Mycobacterium ulcerans transmembrane transport protein 0.0038 0.0012 0.0317
Echinococcus granulosus intermediate filament protein 0.0137 0.007 0.0073
Onchocerca volvulus Protein patched homolog 0.0018 0 0.0001
Schistosoma mansoni inositol monophosphatase 0.016 0.0084 0.0087
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0067 0.0029 0.0279
Brugia malayi beta-lactamase family protein 0.0621 0.0356 0.3471
Loa Loa (eye worm) hypothetical protein 0.0063 0.0027 0.0261
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0074 0.0033 0.0926
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0013 0.0126
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0025 0.0004 0.0038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0038 0.0012 0.033
Schistosoma mansoni Smad4 0.0063 0.0027 0.0028
Echinococcus multilocularis fk506 binding protein 0.0025 0.0004 0.0004
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0055 0.0022 0.0215
Brugia malayi mothers against decapentaplegic homolog 3 0.0028 0.0006 0.0058
Onchocerca volvulus 0.0067 0.0029 0.0345
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0039 0.0012 0.0013
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni methyl-cpg binding protein mbd 0.005 0.0019 0.002
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0245 0.0134 0.0575
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0081 0.0037 0.0039
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0088 0.0042 0.1167
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0011 0.0103
Schistosoma mansoni nuclear hormone receptor 0.0095 0.0046 0.0048
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0067 0.0029 0.003
Onchocerca volvulus 0.055 0.0314 0.378
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.016 0.0084 0.0817
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Brugia malayi kap beta 3 protein 0.0031 0.0008 0.0074
Brugia malayi glutamate--cysteine ligase 0.013 0.0066 0.0643
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0025 0.0004 0.0106
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0031 0.0301
Brugia malayi AMP-binding enzyme family protein 0.0189 0.0101 0.0982
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) AGC/PKG protein kinase 0.0038 0.0012 0.0115
Echinococcus granulosus cGMP dependent protein kinase 1 0.0038 0.0012 0.0012
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0002 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0216 0.0117 0.0122
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0081 0.0037 0.0361
Onchocerca volvulus 0.0061 0.0026 0.0308
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0009
Schistosoma mansoni hypothetical protein 0.1745 0.1019 0.1064
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0256 0.0141 0.0602
Trypanosoma cruzi trypanothione reductase, putative 0.0064 0.0027 0.0767
Schistosoma mansoni immunophilin 0.0021 0.0002 0.0002
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0007 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0307 0.0171 0.0178
Loa Loa (eye worm) hypothetical protein 0.0067 0.0029 0.0279
Echinococcus multilocularis bloom syndrome protein 0.0026 0.0005 0.0005
Brugia malayi CHD4 protein 0.0036 0.0011 0.0105
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Brugia malayi TAR-binding protein 0.0307 0.0171 0.1666
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0095 0.0046 0.0048
Schistosoma mansoni smad1 5 8 and 0.0063 0.0027 0.0028
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0182 0.0097 0.0101
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0255 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0189 0.0101 0.0982
Schistosoma mansoni bromodomain containing protein 0.0024 0.0004 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0095 0.0046 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0037 0.0039
Brugia malayi hypothetical protein 0.0067 0.0029 0.0279
Loa Loa (eye worm) hypothetical protein 0.1441 0.084 0.8193
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.001 0.0098
Brugia malayi Serotonin receptor 0.0061 0.0026 0.025
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0067 0.0029 0.0279
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0038 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0042 0.0405
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0064 0.0027 0.0115
Plasmodium vivax SET domain containing protein 0.0022 0.0003 0.0071
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0064 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0095 0.0046 0.0446
Onchocerca volvulus 0.031 0.0172 0.2073
Trichomonas vaginalis immunophilin, putative 0.0025 0.0004 0.0037
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0067 0.0029 0.003
Trichomonas vaginalis abcb9, putative 0.0022 0.0002 0.0023
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0064 0.0027 0.0763
Brugia malayi ecdysteroid receptor 0.0095 0.0046 0.0446
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0756
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.0127
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0067 0.0029 0.003
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0026 0.0027
Trypanosoma brucei PAB1-binding protein , putative 0.018 0.0095 0.2681
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0007 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0216 0.0117 0.3282
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Brugia malayi 6-phosphofructokinase 0.0131 0.0067 0.0652
Mycobacterium tuberculosis Probable oxidoreductase 0.0304 0.0169 0.0722
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0038 0.0012 0.0114
Brugia malayi phosphofructokinase 0.0131 0.0067 0.0652
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0002 0.0003
Echinococcus multilocularis cysteine protease 0.0035 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0007 0.0067
Echinococcus granulosus importin subunit beta 1 0.0163 0.0086 0.009
Echinococcus multilocularis serotonin receptor 0.0061 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0023 0.0227
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0067 0.0029 0.0279
Schistosoma mansoni patched 1 0.0129 0.0065 0.0068
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni ferritin light chain 0.0021 0.0002 0.0002
Onchocerca volvulus 0.0061 0.0026 0.0308
Onchocerca volvulus Neuropeptide F receptor homolog 0.0061 0.0026 0.0308
Toxoplasma gondii aldehyde dehydrogenase 0.0216 0.0117 0.3288
Leishmania major hypothetical protein, conserved 0.0621 0.0356 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.005 0.0019 0.0187
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0141 0.0073 0.031
Brugia malayi Importin beta-1 subunit 0.0163 0.0086 0.0837
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0067 0.0029 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0088 0.0042 0.1209
Echinococcus multilocularis cpg binding protein 0.0084 0.0039 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0189 0.0101 0.282
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0007 0.0197
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0304 0.0169 0.0722
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0002 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.018 0.0095 0.5325
Brugia malayi jmjC domain containing protein 0.0046 0.0016 0.016
Brugia malayi hypothetical protein 0.0027 0.0005 0.0049
Mycobacterium tuberculosis Conserved protein 0.0621 0.0356 0.1525
Giardia lamblia PHD finger protein 15 0.003 0.0007 0.0368
Loa Loa (eye worm) hypothetical protein 0.0233 0.0127 0.124
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0038 0.0012 0.0049
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0007 0.0007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0021 0.0002 0.0048
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0105 0.0051 0.144
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0038 0.0012 0.0012
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0621 0.0356 1
Giardia lamblia Replication factor C, subunit 1 0.003 0.0007 0.0377
Onchocerca volvulus 0.0207 0.0112 0.1346
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0026 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0182 0.0097 0.0945
Brugia malayi Patched family protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0011 0.0103
Trypanosoma brucei DNA damage repair protein, putative 0.0025 0.0004 0.0115
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0022 0.0215
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.003 0.0007 0.0187
Brugia malayi Bromodomain containing protein 0.0044 0.0015 0.0148
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Entamoeba histolytica HEAT repeat domain containing protein 0.0031 0.0008 0.0221
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0047 0.0017 0.0166
Onchocerca volvulus 0.0061 0.0026 0.0308
Schistosoma mansoni peptidase Clp (S14 family) 0.0321 0.0179 0.0187
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0026 0.025
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0038 0.0012 0.0012
Brugia malayi ecdysone receptor 0.0045 0.0016 0.0155
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0005 0.0048
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0021 0.0002 0.0002
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0021 0.0002 0.0007
Echinococcus granulosus geminin 0.3089 0.1813 0.1892
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Onchocerca volvulus 0.0022 0.0002 0.0029
Loa Loa (eye worm) isocitrate dehydrogenase 0.0021 0.0002 0.0017
Plasmodium vivax DNA repair protein REV1, putative 0.0025 0.0004 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0095 0.0046 0.0446
Mycobacterium ulcerans transcriptional regulatory protein 0.0038 0.0012 0.0317
Onchocerca volvulus 0.0067 0.0029 0.035
Echinococcus granulosus histone acetyltransferase KAT2B 0.0284 0.0157 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0031 0.0301
Entamoeba histolytica hypothetical protein 0.06 0.0344 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0105 0.0051 0.2901
Trypanosoma cruzi cAMP binding protein, putative 0.0038 0.0012 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0007 0.0067
Mycobacterium tuberculosis Probable lipase LipD 0.0621 0.0356 0.1525
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0007 0.0392
Onchocerca volvulus 0.0061 0.0026 0.0308
Brugia malayi beta-lactamase 0.0621 0.0356 0.3471
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0055 0.0022 0.0215
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Brugia malayi Protein cec-1. 0.0026 0.0005 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0007 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0007 0.0067
Brugia malayi Dopamine receptor 0.0061 0.0026 0.025
Brugia malayi multidrug resistance protein 3 0.0022 0.0002 0.0023
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0055 0.0022 0.0617
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.001 0.0289
Onchocerca volvulus 0.0018 0 0.0001
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0038 0.0012 0.0114
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0216 0.0117 0.0122
Echinococcus granulosus zinc finger protein 0.0069 0.003 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Brugia malayi Ets-domain containing protein 0.0047 0.0017 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0004 0.0115
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0081 0.0037 0.0037
Echinococcus multilocularis tar DNA binding protein 0.0307 0.0171 0.0171
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0055 0.0022 0.0023
Echinococcus multilocularis GA binding protein alpha chain 0.0047 0.0017 0.0017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.001 0.0098
Toxoplasma gondii cathepsin CPL 0.0035 0.001 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0304 0.0169 0.4733
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0026 0.0027
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0067 0.0029 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0068
Echinococcus granulosus importin 5 0.0031 0.0008 0.0008
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0026 0.0005 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0005 0.0048
Trypanosoma brucei importin beta-1 subunit, putative 0.0163 0.0086 0.2412
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0068 0.1918
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0074 0.0033 0.0915
Trypanosoma brucei polo-like protein kinase 0.0081 0.0037 0.1039
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0029 0.0029
Mycobacterium ulcerans DNA polymerase IV 0.0081 0.0037 0.1028
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.005 0.0019 0.0019
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0016 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0007 0.0067
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0105 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0067
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0007 0.0197
Schistosoma mansoni neuropeptide receptor 0.0061 0.0026 0.0027
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0003 0.0031
Brugia malayi photoreceptor-specific nuclear receptor 0.0403 0.0227 0.2219
Plasmodium vivax gamma-glutamylcysteine synthetase, putative 0.013 0.0066 0.1851
Loa Loa (eye worm) kap beta 3 protein 0.0031 0.0008 0.0074
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0173 0.0091 0.0095
Schistosoma mansoni hypothetical protein 0.0087 0.0041 0.0042
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0011 0.0011
Echinococcus multilocularis sterol regulatory element binding protein 0.0129 0.0065 0.0065
Schistosoma mansoni importin-beta 2 0.0031 0.0008 0.0008
Echinococcus multilocularis mothers against decapentaplegic 6 0.0028 0.0006 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0225 0.0122 0.3439
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0182 0.0097 0.0945
Trypanosoma brucei cAMP response protein 1, putative 0.0038 0.0012 0.0327
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0767
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0021 0.0002 0.0002
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0067 0.0029 0.003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.1549 0.0904 0.8818
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.001 0.01
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0026 0.0026
Onchocerca volvulus 0.0035 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.008 0.0037 0.0358
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0002 0.0065
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0026 0.025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0028
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0082 0.0038 0.1054
Onchocerca volvulus Serine\/threonine kinase homolog 0.0081 0.0037 0.0445
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0025 0.0004 0.0195
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0 0.0003
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0095 0.0046 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0189 0.0101 0.2821
Brugia malayi putative neuropeptide receptor 0.0061 0.0026 0.025
Trichomonas vaginalis glutaminase, putative 0.0562 0.0321 0.3132
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0019 0.002
Schistosoma mansoni amine GPCR 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0031 0.0301
Toxoplasma gondii glutamate-cysteine ligase, catalytic subunit domain-containing protein 0.013 0.0066 0.185
Echinococcus multilocularis peptidase Clp (S14 family) 0.0211 0.0114 0.0114
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Plasmodium vivax flap endonuclease 1, putative 0.0019 0 0.0012
Leishmania major DNA polymerase kappa, putative 0.0025 0.0004 0.0104
Loa Loa (eye worm) patched family protein 0.0018 0 0.0001
Mycobacterium ulcerans bacterioferritin BfrA 0.0021 0.0002 0.0045
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0074 0.0033 0.0959
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0016 0.0155
Schistosoma mansoni DNA ligase IV 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Schistosoma mansoni importin beta-1 0.0163 0.0086 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0253 0.0139 0.1356
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1549 0.0904 0.0904
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0023
Brugia malayi exodeoxyribonuclease III family protein 0.0074 0.0033 0.0322
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.03 0.0166 0.4838
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0095 0.0046 0.0048
Brugia malayi G-protein alpha subunit 0.0067 0.0029 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0013 0.0126
Trichomonas vaginalis antibiotic synthetase, putative 0.0055 0.0022 0.0215
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0067 0.1878
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0016 0.016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0022 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0021 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Loa Loa (eye worm) glutaminase 2 0.0562 0.0321 0.3132
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0021 0.0002 0.0048
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0026 0.0026
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0026 0.025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0029 0.0807
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0004 0.0108
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0064 0.0027 0.0756
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0016 0.0016
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0002 0.0003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0095 0.0046 0.0048
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.001 0.01
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0012 0.0012
Echinococcus granulosus g protein coupled receptor 0.0061 0.0026 0.0027
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0085 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.018 0.0095 0.2681
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1549 0.0904 0.0943
Brugia malayi Probable ClpP-like protease 0.0321 0.0179 0.1748
Echinococcus multilocularis lamin 0.0137 0.007 0.007
Mycobacterium tuberculosis Probable esterase LipL 0.0621 0.0356 0.1525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0021 0.02
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0021 0.0002 0.0007
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0064 0.0027 0.0028
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0066 0.0028 0.003
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0002 0.0069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Echinococcus granulosus fmrfamide receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.001 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0189 0.0101 0.0982
Schistosoma mansoni smad1 5 8 and 0.0063 0.0027 0.0028
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.001 0.0561
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0067 0.0029 0.0279
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0055 0.0022 0.0093
Entamoeba histolytica Flap nuclease, putative 0.0019 0 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0026 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0304 0.0169 0.0722
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0181 0.0096 0.0096
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0073 0.0033 0.0318
Mycobacterium ulcerans aldehyde dehydrogenase 0.0216 0.0117 0.3282
Onchocerca volvulus 0.0018 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Loa Loa (eye worm) hypothetical protein 0.03 0.0166 0.1622
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0038 0.0012 0.0327
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Entamoeba histolytica acyl-CoA synthetase, putative 0.0189 0.0101 0.2929
Schistosoma mansoni smdr2 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Brugia malayi RNA recognition motif domain containing protein 0.0307 0.0171 0.1666
Brugia malayi latrophilin 2 splice variant baaae 0.0985 0.0571 0.5568
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0026 0.025
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0067 0.0029 0.003
Plasmodium vivax transportin, putative 0.0031 0.0008 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0037 0.0038
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0007 0.0204
Onchocerca volvulus 0.0061 0.0026 0.0308
Loa Loa (eye worm) transcription factor SMAD2 0.0925 0.0535 0.5223
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.001 0.0289
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0021 0.0002 0.0048
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0141 0.0073 0.3967
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0068 0.1918
Echinococcus granulosus replication factor c subunit 1 0.003 0.0007 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Onchocerca volvulus 0.0055 0.0022 0.0265
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.007 0.0031 0.0032
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.016 0.0084 0.2346
Leishmania major cathepsin L-like protease 0.0134 0.0068 0.1909
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0055 0.0022 0.0619
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0067 0.0652
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0025 0.0004 0.0038
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0004 0.0004
Plasmodium vivax heterochromatin protein 1, putative 0.0026 0.0005 0.0138
Loa Loa (eye worm) MH1 domain-containing protein 0.0063 0.0027 0.0259
Schistosoma mansoni hypothetical protein 0.3089 0.1813 0.1892
Brugia malayi RE15519p 0.0061 0.0026 0.025
Onchocerca volvulus 0.0061 0.0026 0.0308
Schistosoma mansoni DNA polymerase eta 0.012 0.006 0.0063
Echinococcus multilocularis isocitrate dehydrogenase 0.0021 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0033 0.0321
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.001 0.0011
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0026 0.0005 0.0048
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0047 0.0017 0.0168
Echinococcus multilocularis importin 5 0.0031 0.0008 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0095 0.0046 0.0446
Brugia malayi ImpB/MucB/SamB family protein 0.0081 0.0037 0.036
Brugia malayi hypothetical protein 0.0018 0 0.0001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0064 0.0027 0.0765
Echinococcus granulosus g protein coupled receptor 0.0061 0.0026 0.0027
Treponema pallidum exodeoxyribonuclease (exoA) 0.0074 0.0033 0.1749
Brugia malayi Associated with TFs and helicases family protein 0.0026 0.0005 0.0048
Loa Loa (eye worm) RecQ helicase 0.0026 0.0005 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0067 0.0029 0.0279
Brugia malayi PHD-finger family protein 0.003 0.0007 0.0067
Echinococcus granulosus somatostatin receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0339 0.019 0.185
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0029 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.0171
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0047 0.0456
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0067 0.007
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0321 0.0179 0.5034
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0055 0.0022 0.0609
Brugia malayi CHE-14 protein 0.0129 0.0065 0.0637
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0021 0.0002 0.0006
Schistosoma mansoni steroid hormone receptor ad4bp 0.0095 0.0046 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0033 0.1839
Schistosoma mansoni voltage-gated potassium channel 0.0296 0.0164 0.0171
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0026 0.0027
Schistosoma mansoni ferritin 0.0021 0.0002 0.0002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0456 0.0258 0.2521
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 1
Schistosoma mansoni hypothetical protein 0.0061 0.0026 0.0027
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0067 0.0029 0.003
Schistosoma mansoni biogenic amine receptor 0.0061 0.0026 0.0027
Plasmodium vivax thioredoxin reductase, putative 0.0185 0.0099 0.2778
Echinococcus granulosus tar DNA binding protein 0.0307 0.0171 0.0178
Echinococcus granulosus expressed conserved protein 0.0281 0.0156 0.0162
Echinococcus multilocularis neuropeptide receptor 0.0266 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Leishmania major peptidylprolyl isomerase-like protein 0.0025 0.0004 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0031 0.0301
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0321 0.0179 0.5034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.031 0.0172 0.1681
Schistosoma mansoni immunophilin 0.0025 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.002 0.0197
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.0005 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0063 0.0027 0.0259
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.001 0.001
Trichomonas vaginalis ferritin, putative 0.0021 0.0002 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0163 0.0086 0.0838
Entamoeba histolytica hypothetical protein 0.06 0.0344 1
Echinococcus granulosus neuropeptide s receptor 0.1153 0.067 0.0699
Brugia malayi steroid hormone receptor 0.0095 0.0046 0.0446
Loa Loa (eye worm) hypothetical protein 0.0383 0.0216 0.2103
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0304 0.0169 0.0176
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0 0.0008
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0026 0.0026
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.008 0.0037 0.0358
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trichomonas vaginalis inositol monophosphatase, putative 0.016 0.0084 0.0817
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0004 0.0004
Brugia malayi Patched related family protein 4 0.0018 0 0.0001
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0026 0.0005 0.0005
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0007 0.0191
Schistosoma mansoni multidrug resistance protein 0.0022 0.0002 0.0003
Echinococcus multilocularis expressed conserved protein 0.0281 0.0156 0.0156
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0007 0.0191
Mycobacterium tuberculosis Probable dehydrogenase 0.0256 0.0141 0.0602
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0038 0.0012 0.0114
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0067 0.187
Leishmania major mitochondrial DNA polymerase beta 0.0476 0.027 0.7597
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0038 0.0012 0.0012
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0067 0.0285
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0019 0.0187
Onchocerca volvulus 0.0018 0 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0026 0.0026
Onchocerca volvulus Bile acid receptor homolog 0.0095 0.0046 0.055
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0042 0.0405
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0081 0.0037 0.0037
Trichomonas vaginalis penicillin-binding protein, putative 0.0621 0.0356 0.3471
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0067 0.0652
Brugia malayi neuropeptide F receptor 0.0061 0.0026 0.025
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0476 0.027 0.76
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0064 0.0027 0.1429
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0016 0.0017
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Brugia malayi Myosin head containing protein 0.0018 0 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0105 0.0052 0.0054
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0004 0.0108
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0055 0.0022 0.0609
Onchocerca volvulus 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0185 0.0099 0.2778
Plasmodium falciparum acyl-CoA synthetase 0.0141 0.0073 0.4047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0016 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0043 0.0416
Plasmodium vivax vivapain-2 0.0035 0.001 0.0282
Schistosoma mansoni hypothetical protein 0.0025 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0031 0.0008 0.0202
Entamoeba histolytica acyl-coA synthetase, putative 0.0189 0.0101 0.2929
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0055 0.0022 0.0641
Mycobacterium tuberculosis Conserved hypothetical protein 0.0081 0.0037 0.0157
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0016 0.0155
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0093 0.0044 0.1241
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0067 0.0029 0.003
Trypanosoma brucei glucosidase, putative 0.0036 0.0011 0.0296
Echinococcus granulosus patatin phospholipase domain containing protein 0.0038 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0154 0.008 0.2249
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0055 0.0022 0.0609
Brugia malayi larval opioid receptor 0.0061 0.0026 0.025
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0081 0.0037 0.1027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0088 0.0042 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0005 0.0048
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0067 0.0029 0.0279
Brugia malayi tailless protein 0.0045 0.0016 0.0155
Echinococcus multilocularis chromobox protein 2 0.0026 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0095 0.0046 0.0446
Loa Loa (eye worm) hypothetical protein 0.0208 0.0112 0.1092
Trichomonas vaginalis importin beta-1, putative 0.0133 0.0068 0.0659
Schistosoma mansoni cpg binding protein 0.0074 0.0033 0.0034
Entamoeba histolytica hypothetical protein 0.06 0.0344 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus multilocularis survival motor neuron protein 1 0.1519 0.0886 0.0886
Brugia malayi beta-lactamase family protein 0.0621 0.0356 0.3471
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0026 0.0026
Brugia malayi conserved hypotetical protein 0.0045 0.0016 0.0155
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0047 0.0456
Loa Loa (eye worm) hypothetical protein 0.03 0.0166 0.1622
Loa Loa (eye worm) hypothetical protein 0.0063 0.0027 0.0261
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0189 0.0101 0.043
Echinococcus multilocularis chromobox protein 1 0.0161 0.0085 0.0085
Echinococcus multilocularis thioredoxin glutathione reductase 0.0186 0.0099 0.0099
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0016 0.0155
Echinococcus multilocularis G protein coupled receptor 139 0.0266 0.0146 0.0146
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0067 0.0029 0.003
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0000070463 0.0000027389
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0055 0.0022 0.0609
Entamoeba histolytica hypothetical protein 0.003 0.0007 0.0204
Onchocerca volvulus 0.0035 0.001 0.0121
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.001 0.0098
Toxoplasma gondii HEAT repeat-containing protein 0.0163 0.0086 0.2411
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0061 0.0026 0.0308
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Onchocerca volvulus 0.0061 0.0026 0.0308
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0708
Trypanosoma cruzi cAMP response protein 1 0.0038 0.0012 0.0327
Onchocerca volvulus 0.0035 0.001 0.0121
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0002 0.0069
Entamoeba histolytica hypothetical protein 0.0133 0.0068 0.1967
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0711
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0271 0.0149 0.0149
Brugia malayi CXXC zinc finger family protein 0.0074 0.0033 0.0321
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni neuropeptide receptor 0.0061 0.0026 0.0027
Leishmania major hypothetical protein, unknown function 0.0038 0.0012 0.0316
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0002 0.0002
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0026 0.0005 0.0136
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0005 0.0044
Loa Loa (eye worm) cysteine protease 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trypanosoma brucei unspecified product 0.0056 0.0022 0.0622
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0067 0.0029 0.0279
Echinococcus granulosus neuropeptide receptor 0.0266 0.0146 0.0153
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0476 0.027 0.76
Trichomonas vaginalis adenylate cyclase type, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis ran, putative 0.0105 0.0051 0.05
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0007 0.0192
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0016 0.0155
Mycobacterium tuberculosis Probable lipase LipE 0.0621 0.0356 0.1525
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0016 0.0155
Mycobacterium ulcerans acyl-CoA synthetase 0.0189 0.0101 0.2821
Schistosoma mansoni hypothetical protein 0.0456 0.0258 0.027
Schistosoma mansoni hypothetical protein 0.0124 0.0063 0.0065
Brugia malayi hypothetical protein 0.005 0.0019 0.0187
Onchocerca volvulus Alhambra homolog 0.003 0.0007 0.0083
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0088 0.0042 0.1167
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.016 0.0084 0.2353
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Brugia malayi nuclear receptor RXR 0.0045 0.0016 0.0155
Echinococcus granulosus lamin dm0 0.0137 0.007 0.0073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0456 0.0258 0.027
Schistosoma mansoni GTP-binding protein alpha subunit 0.0067 0.0029 0.003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0095 0.0046 0.0048
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0055 0.0022 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.017
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0097 0.0047 0.0563
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0085 0.0828
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0096 0.01
Echinococcus multilocularis ubiquitin specific protease 41 0.0064 0.0027 0.0027
Echinococcus granulosus Smad4 0.0063 0.0027 0.0028
Schistosoma mansoni ferritin 0.0021 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Loa Loa (eye worm) ctsf protein 0.0035 0.001 0.0098
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0093 0.0044 0.1241
Leishmania major protein kinase A regulatory subunit, putative 0.0038 0.0012 0.0316
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0025 0.0004 0.0038
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0016 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0026 0.025
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0026 0.0005 0.0143
Brugia malayi RNA, U transporter 1 0.0465 0.0264 0.2573
Echinococcus multilocularis glutamate cysteine ligase, catalytic subunit 0.013 0.0066 0.0066
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0043 0.0015 0.0015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0093 0.0044 0.0431
Echinococcus granulosus Niemann Pick C1 protein 0.0428 0.0242 0.0253
Echinococcus multilocularis voltage gated potassium channel 0.008 0.0037 0.0037
Loa Loa (eye worm) patched family protein 0.0018 0 0.0001
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0055 0.0022 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.001 0.001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0026 0.0026
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0081 0.0037 0.0037
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0105 0.0051 0.144
Schistosoma mansoni hypothetical protein 0.0124 0.0063 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0055 0.0022 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0043 0.0015 0.0015
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0025 0.0004 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0026 0.0026
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0067 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0124 0.0063 0.0065
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0211 0.0114 0.319
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0022 0.0609
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Schistosoma mansoni chromobox protein 0.0026 0.0005 0.0005
Brugia malayi Patched family protein 0.0018 0 0.0001
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0002 0.0069
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0026 0.0027
Schistosoma mansoni hypothetical protein 0.0026 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Echinococcus multilocularis methyl CpG binding domain protein 2 0.005 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0095 0.0046 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Loa Loa (eye worm) fli-1 protein 0.0142 0.0073 0.0716
Chlamydia trachomatis DNA ligase 0.003 0.0007 0.0263
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0025 0.0004 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Echinococcus multilocularis ecdysone induced protein 78C 0.0095 0.0046 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0064 0.0027 0.0756
Brugia malayi Valyl-tRNA synthetase 0.0026 0.0005 0.0048
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Schistosoma mansoni RAR-like nuclear receptor 0.0095 0.0046 0.0048
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.016 0.0084 0.2345
Brugia malayi DKFZp564C0469 protein 0.003 0.0007 0.0069
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0038 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0255 0.014 0.0146
Entamoeba histolytica cysteine protease, putative 0.0035 0.001 0.0292
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0064 0.0027 0.0767
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.001 0.0011
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0055 0.0022 0.1229
Brugia malayi Patched family protein 0.0018 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.0171
Echinococcus multilocularis protein dispatched 1 0.0147 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0067 0.0029 0.0279
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0074 0.0033 0.014
Echinococcus granulosus glutamate cysteine ligase catalytic subunit 0.013 0.0066 0.0069
Schistosoma mansoni ferritin 0.0021 0.0002 0.0002
Plasmodium falciparum transportin 0.0031 0.0008 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0021 0.02
Brugia malayi M-phase phosphoprotein, mpp8 0.0026 0.0005 0.0048
Loa Loa (eye worm) Smad1 0.0063 0.0027 0.0259
Trichomonas vaginalis fk506-binding protein, putative 0.0025 0.0004 0.0037
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0001 0.0001
Echinococcus granulosus mothers against decapentaplegic 5 0.0063 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Onchocerca volvulus 0.0035 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0007 0.0067
Brugia malayi hypothetical protein 0.0018 0 0.0001
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0055 0.0022 0.0609
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trypanosoma brucei hypothetical protein, conserved 0.0621 0.0356 1
Brugia malayi MH2 domain containing protein 0.0925 0.0535 0.5223
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0007 0.0069
Trypanosoma brucei target of rapamycin kinase 3, putative 0.007 0.0031 0.0868
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0256 0.0141 0.0602
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0038 0.0012 0.0114
Brugia malayi G-protein coupled receptor 0.0061 0.0026 0.025
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0025 0.0004 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.001 0.0562
Echinococcus multilocularis muscleblind protein 0.0333 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0321 0.0179 0.1748
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0022 0.0093
Brugia malayi hypothetical protein 0.0018 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Onchocerca volvulus 0.0023 0.0003 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus granulosus FTZ F1 alpha 0.0504 0.0287 0.0299
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0154 0.008 0.0343
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.016 0.0084 0.2354
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0035 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Onchocerca volvulus 0.0055 0.0022 0.0265
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0026 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.018 0.0095 0.5325
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0067 0.1878
Schistosoma mansoni biogenic amine receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0005 0.0048
Echinococcus granulosus single minded 2 0.0025 0.0004 0.0004
Onchocerca volvulus 0.0621 0.0356 0.4282
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0189 0.0101 0.2821
Brugia malayi Dopamine receptor protein 2 0.0061 0.0026 0.025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Entamoeba histolytica Ran family GTPase 0.0105 0.0051 0.1491
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0038 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni opsin-like receptor 0.0061 0.0026 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0037 0.1038
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0067 0.007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0216 0.0117 0.0501
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0271 0.0149 0.1458
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0015
Brugia malayi hypothetical protein 0.0116 0.0058 0.0564
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0026 0.025
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0026 0.0027
Schistosoma mansoni 60S ribosomal protein L21 0.0042 0.0014 0.0015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1549 0.0904 0.0943
Onchocerca volvulus Protein ultraspiracle homolog 0.0095 0.0046 0.055
Onchocerca volvulus 0.0061 0.0026 0.0308
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0055 0.0022 0.0216
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0088 0.0042 0.1157
Schistosoma mansoni inositol monophosphatase 0.016 0.0084 0.0087
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0299 0.0166 0.0173
Echinococcus granulosus voltage gated potassium channel 0.008 0.0037 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0095 0.0046 0.0446
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0026 0.0026
Brugia malayi intermediate filament protein 0.0137 0.007 0.0683
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0038 0.0012 0.065
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0026 0.025
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Onchocerca volvulus 0.0045 0.0016 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0055 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.009 0.0043 0.0417
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0001 0.0001
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0985 0.0571 0.5568
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0026 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0189 0.0101 0.2821
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0016 0.0017
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0055 0.0022 0.0609
Schistosoma mansoni GTP-binding protein alpha subunit 0.0067 0.0029 0.003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0064 0.0027 0.079
Schistosoma mansoni chromobox protein 0.0161 0.0085 0.0088
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0016 0.0192
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0026 0.0005 0.0274
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0005 0.0005
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0067 0.0029 0.0279
Entamoeba histolytica acyl-CoA synthetase, putative 0.0189 0.0101 0.2929
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Toxoplasma gondii ABC1 family protein 0.0621 0.0356 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Echinococcus granulosus potassium voltage gated channel subfamily H 0.008 0.0037 0.0038
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.06 0.0344 0.0359
Schistosoma mansoni gabp alpha 0.0047 0.0017 0.0018
Echinococcus granulosus thioredoxin glutathione reductase 0.0186 0.0099 0.0104
Brugia malayi cytoplasmic intermediate filament protein 0.0073 0.0033 0.0318
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0026 0.0026
Brugia malayi Cyclic-nucleotide gated cation channel 0.0055 0.0022 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0007 0.0197
Mycobacterium leprae Possible transporter protein 0.0025 0.0004 0.01
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0321 0.0179 0.503
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0038 0.0012 0.0012
Trypanosoma cruzi major cysteine proteinase, putative 0.0105 0.0051 0.1444
Loa Loa (eye worm) fibroinase 0.0035 0.001 0.0098
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0026 0.0027
Treponema pallidum NADH oxidase 0.0064 0.0027 0.1429
Schistosoma mansoni apoferritin-2 0.0021 0.0002 0.0002
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0299 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0049
Onchocerca volvulus 0.0061 0.0026 0.0308
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0187
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Onchocerca volvulus 0.003 0.0007 0.0085
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Schistosoma mansoni hypothetical protein 0.0604 0.0346 0.0361
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0006 0.0058
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0007 0.0007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0095 0.0046 0.0446
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0002 0.0003
Brugia malayi nuclear receptor NHR-88 0.0045 0.0016 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0307 0.0171 0.0178
Brugia malayi protein C24B5.3 0.0018 0 0.0001
Mycobacterium leprae Conserved hypothetical protein 0.0038 0.0012 0.0317
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0055 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Conserved protein 0.0621 0.0356 0.1525
Loa Loa (eye worm) patched family protein 0.0018 0 0.0001
Echinococcus granulosus expressed protein 0.0067 0.0029 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1549 0.0904 0.0943
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Schistosoma mansoni Smad4 0.0028 0.0006 0.0006
Schistosoma mansoni zinc finger protein 0.0045 0.0016 0.0017
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor A26 0.1153 0.067 0.067
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0134 0.0069 0.0668
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0105 0.0051 0.05
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0095 0.0046 0.0046
Loa Loa (eye worm) patched family protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Schistosoma mansoni hypothetical protein 0.0456 0.0258 0.027
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Echinococcus granulosus mothers against decapentaplegic 2 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0002 0.0036
Echinococcus multilocularis mothers against decapentaplegic 5 0.0063 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0038 0.0012 0.0012
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0143 0.0074 0.2068
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0055 0.0022 0.0022
Entamoeba histolytica serine/threonine protein kinase, putative 0.0081 0.0037 0.1076
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0067 0.0029 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0004 0.0108
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0067 0.0029 0.0279
Loa Loa (eye worm) phosphatidylinositol 3 0.0088 0.0042 0.0405
Loa Loa (eye worm) hypothetical protein 0.1519 0.0886 0.8645
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0067 0.1945
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0095 0.0046 0.0046
Brugia malayi F/Y-rich N-terminus family protein 0.0044 0.0016 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0011 0.0011
Brugia malayi hypothetical protein 0.018 0.0095 0.0931
Echinococcus granulosus cysteine protease 0.0018 0.0000070463 0.0000073537
Echinococcus multilocularis dnaJ subfamily B 0.0604 0.0346 0.0346
Onchocerca volvulus Glucosylceramidase homolog 0.1151 0.0669 0.8051
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0011 0.0103
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0216 0.0117 0.0117
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0055 0.0022 0.0617
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0182 0.0097 0.0101
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.001 0.0292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.005 0.0019 0.002
Leishmania major hypothetical protein, conserved 0.018 0.0095 0.2673
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0002 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0133 0.0068 0.0659
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0105 0.0051 0.1438
Brugia malayi GnHR receptor homolog 0.0061 0.0026 0.025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Brugia malayi hypothetical protein 0.0045 0.0016 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0231 0.0126 0.0126
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0000070463 0.0000027389
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0005 0.0143
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1441 0.084 0.8193
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0055 0.0022 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0002 0.0069
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0038 0.0012 0.0327
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0067 0.3661
Brugia malayi cathepsin L-like precursor 0.0023 0.0003 0.0031
Trypanosoma brucei gamma-glutamylcysteine synthetase 0.013 0.0066 0.1851
Schistosoma mansoni acetyl-CoA synthetase 0.0055 0.0022 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0034 0.0331
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0026 0.0027
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0025 0.0004 0.0038
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0029 0.0284
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0025 0.0004 0.0038
Brugia malayi glutathione reductase 0.0185 0.0099 0.0964
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0026 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0025 0.0004 0.0112
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0025 0.0004 0.0215
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0025 0.0004 0.0098
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0621 0.0356 0.1525
Schistosoma mansoni hypothetical protein 0.031 0.0172 0.018
Onchocerca volvulus 0.0061 0.0026 0.0308
Trichomonas vaginalis abcb9, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0081 0.0037 0.0157
Onchocerca volvulus 0.0067 0.0029 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Schistosoma mansoni cpg binding protein 0.0084 0.0039 0.004
Brugia malayi hypothetical protein 0.0147 0.0076 0.0743
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0122 0.0061 0.1726
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0095 0.0046 0.0446
Echinococcus granulosus dnaJ subfamily B 0.0604 0.0346 0.0361
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0026 0.0027
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Onchocerca volvulus 0.0061 0.0026 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Echinococcus granulosus hyperpolarization activated cyclic 0.0055 0.0022 0.0023
Schistosoma mansoni hypothetical protein 0.0061 0.0026 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0038 0.0012 0.0012
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0055 0.0022 0.0609
Loa Loa (eye worm) hypothetical protein 0.055 0.0314 0.3064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Schistosoma mansoni chromobox protein 0.0026 0.0005 0.0005
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0028 0.0006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0129 0.0065 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0023 0.0003 0.0075
Echinococcus multilocularis dna polymerase eta 0.012 0.006 0.006
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0067 0.1869
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0043 0.0015 0.0421
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.0027 0.0265
Trypanosoma brucei cAMP binding protein, putative 0.0038 0.0012 0.0327
Schistosoma mansoni histamine h1 receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1745 0.1019 0.9945
Schistosoma mansoni intermediate filament proteins 0.0137 0.007 0.0073
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0002 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0095 0.0046 0.0048
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Echinococcus granulosus ferritin 0.0021 0.0002 0.0002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0088 0.0042 0.1157
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0074 0.0033 0.0033
Schistosoma mansoni amine GPCR 0.0061 0.0026 0.0027
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0007 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0161 0.0085 0.0824
Brugia malayi G-protein coupled receptor 0.0061 0.0026 0.025
Onchocerca volvulus 0.0018 0 0.0001
Echinococcus multilocularis expressed protein 0.0067 0.0029 0.0029
Leishmania major acetyl-CoA synthetase, putative 0.0055 0.0022 0.0608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.017
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0321 0.0179 0.0179
Onchocerca volvulus 0.0038 0.0012 0.014
Onchocerca volvulus 0.0038 0.0012 0.014
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0163 0.0086 0.0089
Mycobacterium ulcerans glutaminase 0.0562 0.0321 0.9024
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0007 0.0066
Echinococcus granulosus ubiquitin specific protease 41 0.0064 0.0027 0.0028
Onchocerca volvulus Cathepsin L homolog 0.0035 0.001 0.0121
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0307 0.0171 0.1666
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0105 0.0051 0.05
Brugia malayi Steroid receptor seven-up type 2 0.0095 0.0046 0.0446
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0095 0.0046 0.0446
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0007 0.0068
Mycobacterium ulcerans beta-lactamase 0.0621 0.0356 1
Schistosoma mansoni survival motor neuron protein 0.031 0.0172 0.018
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0011 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0005 0.0143
Echinococcus multilocularis FTZ F1 alpha 0.0182 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0003 0.0031
Echinococcus multilocularis somatostatin receptor 0.0061 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0031 0.0301
Echinococcus granulosus peptidase Clp S14 family 0.0211 0.0114 0.0119
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0064 0.0027 0.1523
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0007 0.0067
Echinococcus granulosus histone lysine methyltransferase setb 0.0231 0.0126 0.0131
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0042 0.0044
Echinococcus granulosus dna polymerase eta 0.012 0.006 0.0063
Brugia malayi MH1 domain containing protein 0.0063 0.0027 0.0259
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0026 0.0027
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0025 0.0004 0.0195
Brugia malayi AMP-binding enzyme family protein 0.0189 0.0101 0.0982
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0002 0.0003
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0004 0.0108
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0055 0.0022 0.0023
Leishmania major importin beta-1 subunit, putative 0.0133 0.0068 0.189
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0036 0.2024
Leishmania major cathepsin L-like protease 0.0035 0.001 0.0271
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0064 0.0027 0.1429
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.016 0.0084 0.0817
Schistosoma mansoni transcription factor LCR-F1 0.06 0.0344 0.0358
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0025 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0026 0.0026
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0025 0.0004 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.001 0.0098
Leishmania major fk506-binding protein 1-like protein 0.0025 0.0004 0.0096
Echinococcus multilocularis translational activator gcn1 0.0031 0.0008 0.0008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0757
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0007 0.0181
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0064 0.0027 0.0757
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0064 0.0027 0.0027
Leishmania major protein kinase, putative 0.0038 0.0012 0.032
Brugia malayi SET domain containing protein 0.0035 0.001 0.0095
Loa Loa (eye worm) heterochromatin protein 1 0.0161 0.0085 0.0825
Schistosoma mansoni multidrug resistance protein 0.0022 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0004 0.004
Echinococcus granulosus cGMP dependent protein kinase 1 0.0038 0.0012 0.0012
Schistosoma mansoni kinase 0.0041 0.0014 0.0014
Giardia lamblia Kinase, PLK 0.0081 0.0037 0.2086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0031
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0027 0.077
Brugia malayi glutaminase DH11.1 0.0562 0.0321 0.3132
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0002 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0067 0.0029 0.0279
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0067 0.0029 0.0811
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Echinococcus granulosus transportin 1 0.0031 0.0008 0.0008
Echinococcus multilocularis GPCR, family 2 0.0456 0.0258 0.0258
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0093 0.0044 0.0431
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0025 0.0004 0.0114
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0038 0.0012 0.0326
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0038 0.0012 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Brugia malayi Calcitonin receptor-like protein seb-1 0.1441 0.084 0.8193
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0055 0.0022 0.0215
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0133 0.0068 0.029
Schistosoma mansoni voltage-gated potassium channel 0.0296 0.0164 0.0171
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0067 0.0029 0.003
Schistosoma mansoni bromodomain containing protein 0.0197 0.0106 0.011
Entamoeba histolytica deoxycytidyl transferase, putative 0.0081 0.0037 0.1074
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0011 0.0296
Echinococcus granulosus inositol monophosphatase 1 0.016 0.0084 0.0087
Echinococcus granulosus orexin receptor type 2 0.0061 0.0026 0.0027
Loa Loa (eye worm) flap endonuclease-1 0.0019 0 0.0004
Plasmodium vivax patched family protein, putative 0.0018 0 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0026 0.0026
Schistosoma mansoni ferritin light chain 0.0021 0.0002 0.0002
Echinococcus granulosus GTP binding nuclear protein Ran 0.0105 0.0051 0.0054
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0067 0.0067
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0011 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0189 0.0101 0.282
Loa Loa (eye worm) hypothetical protein 0.0051 0.0019 0.0189
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0047 0.0047
Schistosoma mansoni smad 0.0063 0.0027 0.0028
Echinococcus multilocularis cathepsin L 0.0018 0.0000070463 0.0000070463
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0256 0.0141 0.0602
Loa Loa (eye worm) hypothetical protein 0.0182 0.0097 0.0945
Schistosoma mansoni thyroid hormone receptor 0.0351 0.0196 0.0205
Echinococcus multilocularis cysteine protease 0.0035 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Giardia lamblia NADH oxidase lateral transfer candidate 0.0064 0.0027 0.1533
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0315 0.0176 0.511
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0187
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0025 0.0004 0.0114
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0093 0.0044 0.1243
Brugia malayi MH2 domain containing protein 0.0028 0.0006 0.0058
Schistosoma mansoni biogenic amine receptor 0.0061 0.0026 0.0027
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0004 0.0038
Schistosoma mansoni hypothetical protein 0.0045 0.0016 0.0017
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0225 0.0122 0.3431
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.001 0.0092
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0067 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0456 0.0258 0.2521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus granulosus cathepsin l1 0.0023 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0015 0.0406
Echinococcus granulosus TGF beta signal transducer SmadC 0.0063 0.0027 0.0028
Echinococcus granulosus mothers against decapentaplegic 6 0.0028 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.0171
Echinococcus multilocularis hyperpolarization activated cyclic 0.0055 0.0022 0.0022
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1232 0.0717 0.6992
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Plasmodium falciparum heterochromatin protein 1 0.0026 0.0005 0.0274
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Brugia malayi Smad1 0.0063 0.0027 0.0259
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0002 0.0002
Loa Loa (eye worm) RNA binding protein 0.0307 0.0171 0.1666
Loa Loa (eye worm) hypothetical protein 0.0231 0.0126 0.1227
Echinococcus granulosus bloom syndrome protein 0.0026 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0018
Schistosoma mansoni lamin 0.0137 0.007 0.0073
Treponema pallidum catabolite gene activator (Crp) 0.0038 0.0012 0.0546
Loa Loa (eye worm) hypothetical protein 0.0185 0.0099 0.0962
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0708
Trypanosoma brucei Flagellar Member 6 0.0038 0.0012 0.0327
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0016 0.0017
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0026 0.0027
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0002 0.0002
Trypanosoma cruzi polo-like protein kinase, putative 0.0081 0.0037 0.1039
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0026 0.0026
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0025 0.0004 0.0112
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0038 0.0012 0.0012
Plasmodium falciparum thioredoxin reductase 0.0064 0.0027 0.1523
Schistosoma mansoni zinc finger protein 0.0069 0.003 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Onchocerca volvulus 0.0137 0.007 0.0842
Schistosoma mansoni multidrug resistance protein 0.0022 0.0002 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0026 0.0026
Echinococcus granulosus flap endonuclease 1 0.0019 0 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0026 0.025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0095 0.0046 0.0446
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0011 0.0103
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0007 0.0007
Toxoplasma gondii propionate-CoA ligase 0.0055 0.0022 0.0617
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0095 0.0046 0.0048
Echinococcus multilocularis serotonin receptor 0.0061 0.0026 0.0026
Brugia malayi nuclear receptor NHR-67 0.0045 0.0016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0067 0.0029 0.0279
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0038 0.0012 0.0326
Mycobacterium tuberculosis Probable hydrolase 0.0621 0.0356 0.1525
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0026 0.0027
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0189 0.0101 0.2821
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0111 0.0055 0.1538
Giardia lamblia Glutamate-cysteine ligase 0.013 0.0066 0.3736
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0007 0.0192
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0105 0.0051 0.144
Brugia malayi hypothetical protein 0.03 0.0166 0.1622
Echinococcus granulosus methyl CpG binding domain protein 2 0.005 0.0019 0.002
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0085 0.0828
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.001 0.0447
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0012 0.0114
Onchocerca volvulus Huntingtin homolog 0.0185 0.0099 0.1186
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0026 0.0249
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.007 0.0031 0.0858
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0038 0.0012 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0005 0.0048
Onchocerca volvulus 0.0621 0.0356 0.4282
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0068
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0025 0.0004 0.0114
Trypanosoma cruzi protein kinase A regulatory subunit 0.0038 0.0012 0.0327
Schistosoma mansoni opsin-like receptor 0.0061 0.0026 0.0027
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.06 0.0344 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Brugia malayi hypothetical protein 0.1519 0.0886 0.8645
Brugia malayi Angiotensin-converting enzyme family protein 0.1232 0.0717 0.6992
Leishmania major trypanothione reductase 0.0185 0.0099 0.2769
Echinococcus granulosus chromobox protein 1 0.0161 0.0085 0.0088
Echinococcus multilocularis Smad4 0.0063 0.0027 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.001 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Plasmodium falciparum cGMP-dependent protein kinase 0.0038 0.0012 0.0659
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0067 0.0029 0.0811
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0064 0.0027 0.0028
Brugia malayi Cytochrome P450 family protein 0.002 0.0001 0.0014
Brugia malayi Patched family protein 0.0018 0 0.0001
Leishmania major p-glycoprotein 0.0022 0.0002 0.0055
Trypanosoma brucei DNA damage repair protein, putative 0.0025 0.0004 0.0115
Leishmania major pantothenate kinase subunit, putative 0.0023 0.0003 0.0064
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0002 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.1153 0.067 0.067
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0038 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0047 0.0017 0.0168
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0088 0.0042 0.0405
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0015 0.0144
Schistosoma mansoni ets-related 0.0142 0.0073 0.0077
Trypanosoma cruzi Flagellar Member 6 0.0038 0.0012 0.0327
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0002 0.0069
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0321 0.0179 0.0187
Echinococcus multilocularis peregrin 0.0044 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1754 0.1025 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0004 0.0115
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Trichomonas vaginalis glucosylceramidase, putative 0.1213 0.0705 0.6882
Mycobacterium ulcerans regulatory protein 0.0038 0.0012 0.0317
Echinococcus multilocularis Chromo domain 0.0026 0.0005 0.0005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0026 0.025
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Trypanosoma brucei importin beta-1 subunit, putative 0.0163 0.0086 0.2412
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0004
Brugia malayi Muscleblind-like protein 0.0333 0.0186 0.1816
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0021 0.0002 0.0002
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0055 0.0022 0.0619
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0129 0.0065 0.0637
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0067 0.0029 0.0811
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0026 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0022 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0011 0.0285
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0456 0.0258 0.0258
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0189 0.0101 0.0982
Loa Loa (eye worm) beta-lactamase 0.0621 0.0356 0.3471
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0007 0.0067
Echinococcus granulosus beta LACTamase domain containing family member 0.0621 0.0356 0.0371
Schistosoma mansoni hypothetical protein 0.0061 0.0026 0.0027
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0067 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0189 0.0101 0.043
Leishmania major DNA damage repair protein, putative 0.0025 0.0004 0.0104
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0211 0.0114 0.0487
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Loa Loa (eye worm) patched family protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1441 0.084 0.8193
Brugia malayi Heterochromatin protein 1 0.0161 0.0085 0.0825
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 0.503
Entamoeba histolytica hypothetical protein 0.0026 0.0005 0.0143
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Schistosoma mansoni ran 0.0105 0.0051 0.0053
Leishmania major GTP-binding protein, putative 0.0105 0.0051 0.143
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0064 0.0027 0.0768
Trichomonas vaginalis glucosylceramidase, putative 0.1213 0.0705 0.6882
Trypanosoma cruzi DNA damage repair protein, putative 0.0025 0.0004 0.0115
Loa Loa (eye worm) hypothetical protein 0.0067 0.0029 0.0279
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1549 0.0904 0.0943
Brugia malayi Flap endonuclease-1 0.0019 0 0.0004
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0055 0.0022 0.0608
Mycobacterium tuberculosis Probable reductase 0.0256 0.0141 0.0602
Brugia malayi ORL1-like opioid receptor 0.0061 0.0026 0.025
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0029 0.0806
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0064 0.0027 0.0767
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Brugia malayi Patched family protein 0.0018 0 0.0001
Schistosoma mansoni hypothetical protein 0.0456 0.0258 0.027
Brugia malayi Melatonin receptor type 1A 0.0061 0.0026 0.025
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0085 0.0089
Echinococcus multilocularis transportin 1 0.0031 0.0008 0.0008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0005 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0067 0.0029 0.003
Trichomonas vaginalis glutathione reductase, putative 0.0064 0.0027 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0081 0.0037 0.036
Leishmania major acetyl-CoA synthetase, putative 0.0055 0.0022 0.0608
Schistosoma mansoni hypothetical protein 0.3089 0.1813 0.1892
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0055 0.0022 0.0023
Echinococcus granulosus histone acetyltransferase KAT2B 0.0093 0.0044 0.0046
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0038 0.0012 0.0012
Mycobacterium ulcerans hypothetical protein 0.0189 0.0101 0.2821
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0016 0.0017
Schistosoma mansoni lamin 0.0137 0.007 0.0073
Echinococcus granulosus tumor protein p63 0.3758 0.2207 0.2303
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.001 0.001
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0064 0.0027 0.1523
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0253 0.0139 0.1356
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0002 0.0003
Loa Loa (eye worm) glutamate-cysteine ligase 0.013 0.0066 0.0643
Trypanosoma brucei chrX additional, unordered contigs 0.0025 0.0004 0.0115
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0187
Echinococcus granulosus expressed protein 0.0021 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0025 0.0004 0.0105
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0026 0.025
Echinococcus granulosus Protein patched homolog 1 0.0129 0.0065 0.0068
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0067 0.0029 0.0279
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0055 0.0022 0.0216
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0015 0.0406
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0016 0.0192
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Plasmodium falciparum gamma-glutamylcysteine synthetase 0.013 0.0066 0.3677
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0003 0.0033
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0007 0.0069
Brugia malayi Latrophilin receptor protein 2 0.0456 0.0258 0.2521
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0003 0.0003
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0043 0.0015 0.0141
Echinococcus multilocularis lamin dm0 0.0137 0.007 0.007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0026 0.0027
Schistosoma mansoni hypothetical protein 0.0061 0.0026 0.0027
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0007 0.0196
Loa Loa (eye worm) hypothetical protein 0.0333 0.0186 0.1816
Schistosoma mansoni glutamate-cysteine ligase 0.013 0.0066 0.0069
Giardia lamblia DNA damage repair protein 0.0025 0.0004 0.021
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0031
Plasmodium vivax SET domain protein, putative 0.0181 0.0096 0.2704
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0012 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0621 0.0356 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0074 0.0033 0.0322
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0007 0.0192
Trypanosoma cruzi hypothetical protein, conserved 0.0621 0.0356 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0022 0.0622
Brugia malayi MH1 domain containing protein 0.0035 0.001 0.0097
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0026 0.0027
Trypanosoma brucei ISWI complex protein 0.0045 0.0016 0.0445
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0002 0.0023
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0011 0.0307
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0002 0.0048
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0026 0.0005 0.0136
Plasmodium falciparum importin beta, putative 0.0163 0.0086 0.4791
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0256 0.0141 0.3949
Schistosoma mansoni hypothetical protein 0.06 0.0344 0.0358
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0189 0.0101 0.2821
Onchocerca volvulus 0.0061 0.0026 0.0308
Schistosoma mansoni alpha-glucosidase 0.0139 0.0072 0.0075
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 0.503
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0025 0.0004 0.0038
Brugia malayi AKH receptor 0.0061 0.0026 0.025
Brugia malayi polk-prov protein 0.0025 0.0004 0.004
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0002 0.0023
Schistosoma mansoni amine GPCR 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0055 0.0022 0.0093
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) acetyltransferase 0.0299 0.0166 0.162
Schistosoma mansoni amine GPCR 0.0061 0.0026 0.0027
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0055 0.0022 0.0022
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Leishmania major DNA polymerase eta, putative 0.012 0.006 0.1683
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0031 0.0008 0.0213
Echinococcus granulosus cathepsin L 0.0018 0.0000070463 0.0000073537
Trypanosoma cruzi polo-like protein kinase, putative 0.0081 0.0037 0.1039
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0038 0.0012 0.0641
Echinococcus multilocularis muscleblind protein 1 0.0333 0.0186 0.0186
Mycobacterium leprae Probable lipase LipE 0.0621 0.0356 1
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.0037 0.036
Mycobacterium ulcerans epoxide hydrolase EphA 0.0245 0.0134 0.3767
Mycobacterium ulcerans hypothetical protein 0.0621 0.0356 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0014 0.0015
Trypanosoma brucei unspecified product 0.0081 0.0037 0.1038
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0026 0.0026
Treponema pallidum cyclic nucleotide binding protein 0.0038 0.0012 0.0546
Brugia malayi protein C24B5.3 0.0018 0 0.0001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0081 0.0037 0.1028
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Schistosoma mansoni smad 0.0028 0.0006 0.0006
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0007 0.0068
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0067 0.0652
Trypanosoma cruzi DNA polymerase eta, putative 0.012 0.006 0.1692
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Mycobacterium ulcerans aldehyde dehydrogenase 0.0216 0.0117 0.3282
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0022 0.0093
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.001 0.0098
Toxoplasma gondii NADPH-glutathione reductase 0.0064 0.0027 0.0765
Onchocerca volvulus Cathepsin L homolog 0.0035 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0127 0.0064 0.0626
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0095 0.0046 0.0046
Loa Loa (eye worm) latrophilin receptor protein 2 0.0456 0.0258 0.2521
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0067 0.0652
Brugia malayi hypothetical protein 0.0045 0.0016 0.0155
Schistosoma mansoni immunophilin 0.0025 0.0004 0.0004
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0036 0.2003
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.0005 0.0045
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0002 0.0023
Brugia malayi serine/threonine-protein kinase plk-2 0.0081 0.0037 0.0361
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0026 0.0027
Schistosoma mansoni alpha-glucosidase 0.0139 0.0072 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0038 0.0012 0.0048
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0038 0.0012 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Entamoeba histolytica G protein alpha subunit, putative 0.0067 0.0029 0.0833
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Brugia malayi Thioredoxin reductase 0.0185 0.0099 0.0964
Echinococcus multilocularis importin subunit beta 1 0.0163 0.0086 0.0086
Schistosoma mansoni thyroid hormone receptor 0.0351 0.0196 0.0205
Schistosoma mansoni tar DNA-binding protein 0.0307 0.0171 0.0178
Leishmania major hypothetical protein, conserved 0.0045 0.0016 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0005 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0003 0.0093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0026 0.0026
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0026 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0026 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Brugia malayi Niemann-Pick C1 protein precursor 0.03 0.0166 0.1622
Leishmania major hypothetical protein, conserved 0.0038 0.0012 0.0316
Trichomonas vaginalis adenylate cyclase type III, putative 0.0025 0.0004 0.0038
Brugia malayi sulfakinin receptor protein 0.0061 0.0026 0.025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0133 0.0068 0.029
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0141 0.0073 0.0877
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0088 0.0042 0.0043
Brugia malayi Cathepsin L-like precursor 0.0023 0.0003 0.0031
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0004 0.0038
Toxoplasma gondii exonuclease III APE 0.0074 0.0033 0.0925
Echinococcus granulosus Chromobox protein 3 0.0026 0.0005 0.0005
Brugia malayi hypothetical protein 0.0185 0.0099 0.0961
Leishmania major 4-coumarate:coa ligase-like protein 0.0189 0.0101 0.282
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0068
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0067 0.0652
Echinococcus granulosus lysine specific demethylase 5A 0.0046 0.0016 0.0017
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0016 0.0155
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0002 0.0023
Schistosoma mansoni opsin-like receptor 0.0061 0.0026 0.0027
Echinococcus granulosus ecdysone induced protein 78C 0.0095 0.0046 0.0048
Brugia malayi Egg laying defective protein 4 0.0038 0.0012 0.0115
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0095 0.0046 0.0446
Trypanosoma cruzi ISWI complex protein 0.0045 0.0016 0.0445
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.005 0.0019 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0071 0.0031 0.0304
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.003 0.0007 0.0187
Trichomonas vaginalis abcb9, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0708
Trypanosoma brucei DNA polymerase eta, putative 0.012 0.006 0.1692
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.017
Leishmania major cathepsin L-like protease 0.0134 0.0068 0.1909
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0187 0.01 0.0104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0095 0.0046 0.0048
Loa Loa (eye worm) inositol-1 0.016 0.0084 0.0817
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0016 0.0155
Echinococcus granulosus neuropeptide receptor A26 0.1153 0.067 0.0699
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0026 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0004 0.0115
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus multilocularis microtubule associated protein 2 1.6253 0.9582 0.9582
Echinococcus granulosus survival motor neuron protein 1 0.1519 0.0886 0.0925
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0031
Schistosoma mansoni coup transcription factor 0.0095 0.0046 0.0048
Onchocerca volvulus Protein patched homolog 0.0018 0 0.0001
Schistosoma mansoni nuclear receptor 0.0045 0.0016 0.0017
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1754 0.1025 1
Onchocerca volvulus 0.0061 0.0026 0.0308
Echinococcus multilocularis expressed protein 0.0021 0.0002 0.0002
Schistosoma mansoni chromobox protein 0.0161 0.0085 0.0088
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0026 0.0027
Leishmania major cathepsin L-like protease 0.0134 0.0068 0.1909
Brugia malayi PHD-finger family protein 0.002 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0067 0.0029 0.003
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0026 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0207 0.0112 0.0117
Echinococcus granulosus GA binding protein alpha chain 0.0047 0.0017 0.0018
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.001 0.0287
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0111 0.0055 0.3055
Plasmodium falciparum thioredoxin reductase 0.0185 0.0099 0.5517
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0111 0.0055 0.2978
Onchocerca volvulus 0.03 0.0166 0.2001
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0067 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.0069
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.0007
Plasmodium vivax vivapain-2 0.0035 0.001 0.0282
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0446
Schistosoma mansoni hypothetical protein 0.0081 0.0037 0.0039
Plasmodium vivax importin-beta 2, putative 0.0163 0.0086 0.2412
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0016 0.0017
Giardia lamblia Fructose-bisphosphate aldolase 0.0315 0.0176 1
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.001 0.0287
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0189 0.0101 0.2821
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0067 0.007
Echinococcus granulosus Chromo domain 0.0026 0.0005 0.0005
Mycobacterium ulcerans lipase LipD 0.0621 0.0356 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0011 0.0011
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0081 0.0037 0.0039
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Schistosoma mansoni hypothetical protein 0.0985 0.0571 0.0595
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0007 0.0197
Brugia malayi G protein-coupled receptor 0.0061 0.0026 0.025
Schistosoma mansoni topbp1 0.003 0.0007 0.0007
Schistosoma mansoni Smad4 0.0028 0.0006 0.0006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0767
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0000070463 0.0000027389
Trypanosoma cruzi cAMP response protein 1, putative 0.0038 0.0012 0.0327
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0011 0.0103
Leishmania major DNA polymerase eta, putative 0.0064 0.0027 0.0759
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0068 0.1918
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0026 0.025
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0021 0.0002 0.0045
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0038 0.0012 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0012
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0002 0.0023
Trypanosoma cruzi cruzipain precursor, putative 0.0134 0.0068 0.1918
Mycobacterium tuberculosis Conserved protein 0.0621 0.0356 0.1525
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.018 0.0095 0.0931
Trypanosoma cruzi importin beta-1 subunit, putative 0.0133 0.0068 0.1899
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0055 0.0022 0.0619
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.008 0.0037 0.0037
Treponema pallidum catabolite gene activator 0.0038 0.0012 0.0546
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0137 0.007 0.0683
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0067 0.0652
Loa Loa (eye worm) hypothetical protein 0.012 0.006 0.0588
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.016 0.0084 0.2354
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0055 0.0022 0.0023
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0016 0.0016
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.001 0.0011
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.001 0.0299
Echinococcus multilocularis smad 0.0063 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0018 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0042 0.0405
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0185 0.0099 0.0423
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0007 0.0196
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0038 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0067 0.0029 0.003
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0067 0.187
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0011 0.0103
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0055 0.0022 0.0023
Schistosoma mansoni methyl-cpg binding protein mbd 0.005 0.0019 0.002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0064 0.0027 0.0767
Echinococcus multilocularis sex peptide receptor 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0048
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0002 0.0023
Mycobacterium ulcerans bacterioferritin BfrB 0.0021 0.0002 0.0045
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0038 0.0012 0.0327
Schistosoma mansoni cellular tumor antigen P53 0.055 0.0314 0.0328
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0137 0.0588
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0074 0.0033 0.1749
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0006 0.0058
Loa Loa (eye worm) nuclear factor I 0.0035 0.001 0.0097
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0005 0.0274
Echinococcus multilocularis beta LACTamase domain containing family member 0.0621 0.0356 0.0356
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0026 0.0027
Onchocerca volvulus 0.0189 0.0101 0.1211
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0002 0.0023
Loa Loa (eye worm) intermediate filament protein 0.0137 0.007 0.0683
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0067 0.0029 0.0279
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0007 0.0069
Brugia malayi Pre-SET motif family protein 0.1252 0.0729 0.7109
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0185 0.0099 0.0962
Echinococcus multilocularis hyperpolarization activated cyclic 0.0055 0.0022 0.0022
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0007 0.0197
Loa Loa (eye worm) bromodomain containing protein 0.0059 0.0024 0.0236
Schistosoma mansoni terminal deoxycytidyl transferase 0.0081 0.0037 0.0039
Brugia malayi N-terminal motif family protein 0.0141 0.0073 0.0711
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0026 0.0027
Onchocerca volvulus Huntingtin homolog 0.0185 0.0099 0.1186
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0011 0.0103
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0321 0.0179 0.5035
Brugia malayi Bromodomain containing protein 0.0232 0.0126 0.1229
Brugia malayi hypothetical protein 0.0018 0 0.0001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0026 0.0027
Onchocerca volvulus 0.0045 0.0016 0.0192
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0095 0.0046 0.0446
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0189 0.0101 0.2821
Schistosoma mansoni cpg binding protein 0.0084 0.0039 0.004
Echinococcus granulosus fetal alzheimer antigen falz 0.007 0.0031 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Onchocerca volvulus 0.0018 0 0.0001
Echinococcus granulosus neuropeptide receptor 0.0061 0.0026 0.0027
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0038 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0066 0.0028 0.0276
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0026 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0095 0.0046 0.0046
Plasmodium vivax acyl-CoA synthetase, putative 0.0141 0.0073 0.2038
Loa Loa (eye worm) hypothetical protein 0.0141 0.0073 0.0708
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Loa Loa (eye worm) hypothetical protein 0.0621 0.0356 0.3471
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0026 0.025
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.1549 0.0904 0.8818
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0022 0.0622
Loa Loa (eye worm) hypothetical protein 0.0333 0.0186 0.1816
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0111 0.0055 0.1529
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0026 0.025
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0026 0.025
Mycobacterium ulcerans esterase/lipase LipP 0.0621 0.0356 1
Brugia malayi Patched family protein 0.0018 0 0.0001
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Brugia malayi hypothetical protein 0.06 0.0344 0.3352
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0005 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Echinococcus multilocularis fetal alzheimer antigen, falz 0.007 0.0031 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0621 0.0356 0.0371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0002 0.0002
Schistosoma mansoni alpha glucosidase 0.0036 0.0011 0.0011
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.0097
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0067 0.0029 0.0279
Plasmodium vivax acetyl-CoA synthetase, putative 0.0055 0.0022 0.0619
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0064 0.0027 0.1409
Loa Loa (eye worm) hypothetical protein 0.0064 0.0027 0.0265
Schistosoma mansoni DNA polymerase IV / kappa 0.0025 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Schistosoma mansoni smad1 5 8 and 0.0063 0.0027 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0067 0.0029 0.0279
Loa Loa (eye worm) importin-beta domain-containing protein 0.0031 0.0008 0.0074
Mycobacterium ulcerans hypothetical protein 0.0251 0.0137 0.3855
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0046 0.0446
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Trypanosoma brucei trypanothione reductase 0.0185 0.0099 0.2778
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Onchocerca volvulus 0.0055 0.0022 0.0265
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0038 0.0012 0.0012
Echinococcus multilocularis Chromobox protein 3 0.0026 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0003 0.0031
Trypanosoma cruzi DNA damage repair protein, putative 0.0025 0.0004 0.0115
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Echinococcus granulosus dna polymerase kappa 0.0081 0.0037 0.0039
Brugia malayi MH2 domain containing protein 0.0063 0.0027 0.0259
Echinococcus multilocularis Niemann Pick C1 protein 0.0428 0.0242 0.0242
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0067 0.1945
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0033 0.0321
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.001 0.0561
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0256 0.0141 0.0602
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1549 0.0904 0.0943
Schistosoma mansoni ap endonuclease 0.0074 0.0033 0.0034
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0002 0.0023
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0081 0.0037 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0026 0.0027
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0038 0.0012 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0137 0.007 0.0683
Echinococcus multilocularis musashi 0.0137 0.007 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0004 0.0004
Trypanosoma cruzi target of rapamycin kinase 3 0.007 0.0031 0.0868
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0231 0.0126 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0058
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0011 0.0103
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0064 0.0027 0.1526
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Trichomonas vaginalis hypothetical protein 0.0031 0.0008 0.0074
Echinococcus granulosus smad 0.0063 0.0027 0.0028
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0002 0.0065
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0034
Plasmodium vivax ataxin-2 like protein, putative 0.018 0.0095 0.2681
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0621 0.0356 0.1525
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0064 0.0027 0.0265
Echinococcus granulosus hyperpolarization activated cyclic 0.0055 0.0022 0.0023
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0055 0.0022 0.0609
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0095 0.0046 0.055
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0064 0.0027 0.0767
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0002 0.0069
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0067 0.0029 0.003
Leishmania major cathepsin L-like protease 0.0035 0.001 0.0271
Mycobacterium ulcerans hypothetical protein 0.0038 0.0012 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0181 0.0096 0.2703
Echinococcus multilocularis geminin 0.3089 0.1813 0.1813
Brugia malayi ImpB/MucB/SamB family protein 0.012 0.006 0.0588
Onchocerca volvulus 0.0067 0.0029 0.0345
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0004 0.0115
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0016 0.0155
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0055 0.0022 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0002 0.0046
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0043 0.0015 0.0141
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0002 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0055 0.0022 0.0023
Echinococcus granulosus transcription factor Dp 1 0.0025 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0063 0.0027 0.0259
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0022 0.0093
Echinococcus granulosus Niemann Pick C1 protein 0.03 0.0166 0.0173
Echinococcus granulosus cathepsin l1 0.0035 0.001 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni ran 0.0105 0.0051 0.0053
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis flap endonuclease-1, putative 0.0019 0 0.0004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0456 0.0258 0.0258
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Brugia malayi hypothetical protein 0.003 0.0007 0.0069
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0038 0.0012 0.0326
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0019 0 0.0003
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0088 0.0042 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0068 0.1918
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0067 0.0029 0.0279
Brugia malayi jmjC domain containing protein 0.0097 0.0047 0.0456
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0002 0.0023
Brugia malayi Patched family protein 0.0018 0 0.0001
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0038 0.0012 0.0048
Onchocerca volvulus 0.0061 0.0026 0.0308
Leishmania major regulatory subunit of protein kinase a-like protein 0.0038 0.0012 0.0316
Echinococcus granulosus chromobox protein 1 0.0161 0.0085 0.0088
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0012 0.0048
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0182 0.0097 0.0097
Echinococcus multilocularis dna polymerase kappa 0.0081 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0064 0.0027 0.0028
Schistosoma mansoni apoferritin-2 0.0021 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.002 0.0197
Toxoplasma gondii hypothetical protein 0.0111 0.0055 0.1537
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus granulosus sterol regulatory element binding protein 0.0129 0.0065 0.0068
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0029 0.0807
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0007 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.001 0.0282
Brugia malayi hypothetical protein 0.003 0.0007 0.0069
Echinococcus multilocularis transcription factor Dp 1 0.0025 0.0004 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Trichomonas vaginalis chromobox protein, putative 0.0161 0.0085 0.0824
Giardia lamblia GTOR 0.0088 0.0042 0.2347
Schistosoma mansoni ap endonuclease 0.0074 0.0033 0.0034
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0216 0.0117 0.3281
Toxoplasma gondii histone lysine methyltransferase SET1 0.0161 0.0084 0.2363
Trichomonas vaginalis D-aminoacylase, putative 0.0621 0.0356 0.3471
Trichomonas vaginalis D-aminoacylase, putative 0.0621 0.0356 0.3471
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus multilocularis expressed conserved protein 0.0038 0.0012 0.0012
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0756
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0105 0.0051 0.144
Onchocerca volvulus 0.0035 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0021 0.0002 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Brugia malayi Isocitrate dehydrogenase 0.0021 0.0002 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0095 0.0046 0.0048
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0064 0.0027 0.0029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0007 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0925 0.0535 0.5223
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0011 0.0103
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0025 0.0004 0.0004
Mycobacterium ulcerans hypothetical protein 0.0038 0.0012 0.0317
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0095 0.0046 0.0446
Brugia malayi 6-phosphofructokinase 0.0132 0.0067 0.0654
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0038 0.0012 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0043 0.0416
Echinococcus granulosus microtubule associated protein 2 1.6253 0.9582 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0026 0.0027
Onchocerca volvulus 0.0074 0.0033 0.0396
Loa Loa (eye worm) DR-78 0.0045 0.0016 0.0155
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Brugia malayi neuropeptide F receptor 0.0061 0.0026 0.025
Loa Loa (eye worm) hypothetical protein 0.0055 0.0022 0.0215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0098
Echinococcus multilocularis protein patched 0.0129 0.0065 0.0065
Brugia malayi acetyltransferase, GNAT family protein 0.0299 0.0166 0.162
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Brugia malayi MH1 domain containing protein 0.0035 0.001 0.0097
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.0027 0.0265
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0133 0.0068 0.029
Loa Loa (eye worm) FKBP5 protein 0.0025 0.0004 0.0038
Onchocerca volvulus 0.0137 0.007 0.0842
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0007 0.0007
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0255 0.014 0.0146
Brugia malayi nuclear receptor RXR 0.005 0.0019 0.0187
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0038 0.0012 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0064 0.0027 0.0767
Entamoeba histolytica hypothetical protein 0.06 0.0344 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0012 0.0317
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.0022 0.0215
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0067 0.0029 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0095 0.0046 0.0048
Plasmodium falciparum glutathione reductase 0.0185 0.0099 0.5517
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0037 0.1038
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0003 0.015
Toxoplasma gondii LsmAD domain-containing protein 0.018 0.0095 0.268
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0000070463 0.0000073537
Toxoplasma gondii target of rapamycin (TOR), putative 0.0066 0.0028 0.079
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0271 0.0149 0.0156
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0007 0.0197
Onchocerca volvulus 0.0621 0.0356 0.4282
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0064 0.0027 0.0028
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0015 0.0406
Treponema pallidum cyclic nucleotide binding protein 0.0038 0.0012 0.0546
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0019 0 0.001
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0016 0.0017
Onchocerca volvulus 0.1425 0.0831 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0002 0.0023
Trypanosoma brucei protein kinase A regulatory subunit 0.0038 0.0012 0.0327
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0074 0.0033 0.0917
Schistosoma mansoni tar DNA-binding protein 0.0307 0.0171 0.0178
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.001 0.001
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.0043 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0028 0.0275
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.001 0.0292
Mycobacterium ulcerans acetyl-CoA synthetase 0.0055 0.0022 0.0609
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0621 0.0356 0.3471
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0098
Brugia malayi ABC transporter family protein 0.0022 0.0002 0.0023
Trichomonas vaginalis set domain proteins, putative 0.1425 0.0831 0.8104
Loa Loa (eye worm) TAR-binding protein 0.0307 0.0171 0.1666
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0067 0.1945
Brugia malayi Serotonin receptor 0.0061 0.0026 0.025
Plasmodium vivax glutathione reductase, putative 0.0185 0.0099 0.2778
Trichomonas vaginalis hypothetical protein 0.0026 0.0005 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0133 0.0068 0.029
Onchocerca volvulus 0.0071 0.0031 0.0375
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0088 0.0042 0.1209
Leishmania major cysteine peptidase A (CPA) 0.0035 0.001 0.0271
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0055 0.0022 0.0619
Schistosoma mansoni microtubule-associated protein tau 1.6253 0.9582 1
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0038 0.0012 0.0012
Loa Loa (eye worm) steroid hormone receptor 0.0095 0.0046 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0095 0.0046 0.0446
Plasmodium falciparum phd finger protein, putative 0.003 0.0007 0.0383
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0007 0.0192
Echinococcus granulosus translational activator gcn1 0.0031 0.0008 0.0008
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0002 0.0067
Trichomonas vaginalis mercuric reductase, putative 0.0064 0.0027 0.0266
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0155
Brugia malayi Patched family protein 0.0018 0 0.0001
Echinococcus multilocularis Niemann Pick C1 protein 0.03 0.0166 0.0166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0015 0.0144
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0025 0.0004 0.0004
Loa Loa (eye worm) glutaminase 0.0562 0.0321 0.3132
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0023
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0038 0.0012 0.0327
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0004 0.0115
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0231 0.0126 0.0131
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.001 0.0469
Leishmania major hypothetical protein, conserved 0.0038 0.0012 0.0316
Trichomonas vaginalis adenylate cyclase type, putative 0.0025 0.0004 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0026 0.0026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0074 0.0033 0.0321
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0026 0.025
Leishmania major gamma-glutamylcysteine synthetase, putative 0.013 0.0066 0.1842
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0029 0.0123
Plasmodium falciparum DNA repair protein REV1, putative 0.0025 0.0004 0.0229
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0038 0.0012 0.0012
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0067 0.0029 0.0279
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.001 0.0561
Mycobacterium leprae conserved hypothetical protein 0.0621 0.0356 1
Trichomonas vaginalis taga, putative 0.0022 0.0002 0.0023
Onchocerca volvulus 0.0035 0.001 0.0121
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0037 0.0011 0.031
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0019 0 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0037 0.1038
Brugia malayi topoisomerase 0.003 0.0007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0061 0.0026 0.025
Trypanosoma brucei unspecified product 0.0056 0.0022 0.0622
Brugia malayi hypothetical protein 0.0061 0.0026 0.025
Leishmania major hypothetical protein, conserved 0.0038 0.0012 0.0316
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.001 0.0447
Loa Loa (eye worm) hypothetical protein 0.0113 0.0056 0.0545
Loa Loa (eye worm) oxidoreductase 0.0055 0.0022 0.0215
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0026 0.0027
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0067 0.0029 0.0811
Echinococcus granulosus hypothetical protein 0.0061 0.0026 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0064 0.0027 0.0767
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0064 0.0027 0.0763
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0011 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0024 0.0238
Schistosoma mansoni hypothetical protein 0.0124 0.0063 0.0065
Echinococcus granulosus muscleblind protein 0.0333 0.0186 0.0194
Brugia malayi Patched family protein 0.0018 0 0.0001
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0038 0.0012 0.0012
Schistosoma mansoni ferritin 0.0021 0.0002 0.0002
Trichomonas vaginalis hypothetical protein 0.0025 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0114
Loa Loa (eye worm) hypothetical protein 0.0067 0.0029 0.0279
Schistosoma mansoni hypothetical protein 0.0456 0.0258 0.027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.001 0.0573
Trichomonas vaginalis glucosylceramidase, putative 0.1151 0.0669 0.6526
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0001 0.0001
Echinococcus multilocularis mothers against decapentaplegic 2 0.0028 0.0006 0.0006
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0067 0.0029 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0157 0.0082 0.0803
Mycobacterium tuberculosis Conserved protein 0.0038 0.0012 0.0048
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0002 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0026 0.025
Plasmodium vivax hypothetical protein, conserved 0.0621 0.0356 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1252 0.0729 0.7109
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0026 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0012 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0456 0.0258 0.027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0621 0.0356 0.0371
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0403 0.0227 0.2219
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0321 0.0179 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0189 0.0101 0.0982
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0022 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Brugia malayi Dopamine receptor protein 1 0.0061 0.0026 0.025
Onchocerca volvulus 0.0018 0 0.0001
Brugia malayi chromobox protein homolog 3 0.009 0.0043 0.0417
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0001 0.0014
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0026 0.0027
Onchocerca volvulus 0.0035 0.001 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0027 0.0264
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Treponema pallidum DNA ligase (lig) 0.003 0.0007 0.0285
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0187 0.01 0.01
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0025 0.0004 0.0037
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0081 0.0037 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0074 0.0033 0.0926
Echinococcus multilocularis zinc finger protein 0.0069 0.003 0.003
Toxoplasma gondii hypothetical protein 0.0077 0.0035 0.0973
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.001 0.0011
Entamoeba histolytica hypothetical protein 0.0026 0.0005 0.0143
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0088 0.0042 0.1167
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0007 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.1754 0.1025 1
Schistosoma mansoni nuclear receptor 0.0045 0.0016 0.0017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0074 0.0033 0.0034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0064 0.0027 0.0767
Brugia malayi nuclear hormone receptor 0.0045 0.0016 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0004 0.0038
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0025 0.0004 0.0038
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0021 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.0081 0.0037 0.2084
Entamoeba histolytica myo-inositol monophosphatase, putative 0.016 0.0084 0.2437
Loa Loa (eye worm) G protein alpha subunit 3 0.0067 0.0029 0.0279
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0021 0.0002 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0067 0.0029 0.0029
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0074 0.0033 0.1857
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0022 0.0609
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0064 0.0027 0.0757
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0026 0.0026
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0055 0.0022 0.0619
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0187
Onchocerca volvulus 0.0061 0.0026 0.0308
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0081 0.0037 0.036
Echinococcus granulosus nibrin 0.003 0.0007 0.0007
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0055 0.0022 0.0023
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0011 0.0295
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0315 0.0176 0.1713
Schistosoma mansoni myosin xvIII 0.0061 0.0026 0.0027
Brugia malayi Patched related family protein 12 0.0018 0 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0016 0.0017
Leishmania major cathepsin L-like protease 0.0035 0.001 0.0271
Trichomonas vaginalis D-aminoacylase, putative 0.0621 0.0356 0.3471
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0026 0.0027
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0055 0.0022 0.0215
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.003 0.0007 0.0285
Loa Loa (eye worm) hypothetical protein 0.0137 0.007 0.0683
Mycobacterium tuberculosis Possible penicillin-binding protein 0.3965 0.233 1
Schistosoma mansoni adenoreceptor 0.0061 0.0026 0.0027
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0016 0.0016
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0026 0.025
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0105 0.0051 0.0051
Echinococcus multilocularis tumor protein p63 0.3758 0.2207 0.2207
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0042 0.0014 0.0394
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0026 0.0005 0.0136
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0143 0.0074 0.0315
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0005 0.0138
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.001 0.0573
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0038 0.0012 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0004 0.0115
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0621 0.0356 0.3471
Trichomonas vaginalis antibiotic synthetase, putative 0.0055 0.0022 0.0215
Brugia malayi nuclear hormone receptor 0.0095 0.0046 0.0446
Echinococcus granulosus cpg binding protein 0.0084 0.0039 0.004
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0002 0.0023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0621 0.0356 0.1525
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0008 0.0217
Loa Loa (eye worm) helicase 0.0026 0.0005 0.0048
Brugia malayi MH2 domain containing protein 0.0063 0.0027 0.0259
Echinococcus multilocularis snurportin 1 0.1745 0.1019 0.1019
Loa Loa (eye worm) hypothetical protein 0.0055 0.0022 0.0216
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0043 0.0015 0.0395
Brugia malayi Patched family protein 0.0018 0 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0098
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0025 0.0004 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0027 0.0265
Brugia malayi Intermediate filament tail domain containing protein 0.0137 0.007 0.0683
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0065 0.0636
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0004 0.0038
Brugia malayi hypothetical protein 0.005 0.0019 0.0187

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione ChEMBL. 24703231
Activity (binding) Induction of eumelanogenesis assessed as mushroom tyrosinase-mediated simulation of eumelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in absence of glutathione and presence of H2O2 ChEMBL. 24703231
Activity (binding) Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione ChEMBL. 24703231
Activity (binding) Induction of pheomelanogenesis assessed as mushroom tyrosinase-mediated simulation of pheomelanogenesis by measuring oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 0.65 to 3.2 mM of glutathione and H2O2 ChEMBL. 24703231
Inhibition (binding) Inhibition of mushroom tyrosinase-mediated simulation of pheomelanogenesis assessed as oxidation of L-DOPA at 4.5 to 184.4 mM after 48 hrs by Vis-spectrophotometer analysis in presence of 16.3 to 81.3 mM of glutathione ChEMBL. 24703231
Potency (functional) 2.0787 uM PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 22664  
Annotator: aaronjr@u.washington.edu Comment: Drug: 16037-91-5. chemical inhibition with various inhibitors leads to reduced enzyme activity in vitro; References: 15766869
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium falciparum 4864  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 10677377
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium berghei 4864  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 7628559

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

23 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.