Detailed information for compound 1173339

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.859 | Formula: C21H20ClFN4O5
  • H donors: 0 H acceptors: 5 LogP: 3.06 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@@]1(C)[C@@H](COC(=O)c2ccccc2)O[C@H]([C@]1(C)F)n1cnc2c1ncnc2Cl
  • InChi: 1S/C21H20ClFN4O5/c1-12(28)32-21(3)14(9-30-18(29)13-7-5-4-6-8-13)31-19(20(21,2)23)27-11-26-15-16(22)24-10-25-17(15)27/h4-8,10-11,14,19H,9H2,1-3H3/t14-,19-,20+,21+/m1/s1
  • InChiKey: KMFXMKZVUZGOKU-PLBGURBNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.0381 0.085
Onchocerca volvulus Huntingtin homolog 0.0119 0.0103 0.1065
Schistosoma mansoni caspase-7 (C14 family) 0.0833 0.0869 0.1939
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0109 0.0092 0.0296
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0277 0.0272 0.0919
Echinococcus granulosus caspase 0.0833 0.0869 0.1939
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0022 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Plasmodium vivax importin-beta 2, putative 0.0029 0.0007 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0007 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0087 0.0069 0.0203
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0039 0.0018 0.0057
Echinococcus granulosus hypothetical protein 0.0039 0.0018 0.0039
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.037 0.0373 0.9941
Brugia malayi protein C24B5.3 0.0044 0.0023 0.0076
Mycobacterium ulcerans hypothetical protein 0.037 0.0373 0.994
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0028 0.0092
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0007 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0007 0.0024
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0042 0.014
Echinococcus granulosus retinol dehydrogenase 11 0.0039 0.0018 0.0039
Brugia malayi MH1 domain containing protein 0.0024 0.0001 0.0003
Echinococcus multilocularis carbonyl reductase 1 0.0039 0.0018 0.0018
Brugia malayi nuclear hormone receptor 0.0062 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0021 0.0049
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0036
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0094 0.0316
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0042 0.0436
Plasmodium vivax serine/threonine kinase-1, putative 0.0062 0.0042 0.0143
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0087 0.0069 0.1494
Schistosoma mansoni smad1 5 8 and 0.0043 0.0022 0.0048
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0109 0.0092 0.0296
Echinococcus granulosus Chromobox protein 3 0.0023 0.0000000052477 0.00000001171
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0259 0.0253 0.0565
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.031 0.0308 0.1155
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0109 0.0092 0.0296
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0065 0.1727
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.0141 0.0141
Echinococcus multilocularis steroid dehydrogenase 0.0039 0.0018 0.0018
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0013 0.0013
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0109 0.0092 0.0308
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0147 0.0495
Schistosoma mansoni hypothetical protein 0.0301 0.0298 0.0665
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0051 0.0031 0.0101
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0087 0.0069 0.0229
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.037 0.0373 0.1415
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Chlamydia trachomatis DNA ligase 0.0091 0.0073 0.2488
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0042 0.0143
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0042 0.0094
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Mycobacterium ulcerans fatty-acid-CoA ligase 0.037 0.0373 0.994
Echinococcus granulosus oxidoreductase 0.0039 0.0018 0.0039
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.2167
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0013 0.0045
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0147 0.0327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Brugia malayi jmjC domain containing protein 0.0117 0.01 0.0339
Loa Loa (eye worm) DR-78 0.0029 0.0007 0.0024
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0039 0.0018 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Echinococcus granulosus sterol regulatory element binding protein 0.0312 0.031 0.0692
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Echinococcus multilocularis Niemann Pick C1 protein 0.1039 0.109 0.109
Toxoplasma gondii ABC1 family protein 0.0372 0.0375 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0011 0.0024
Trichomonas vaginalis chromobox protein, putative 0.014 0.0126 0.0425
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0036 0.34
Loa Loa (eye worm) hypothetical protein 0.0109 0.0092 0.0311
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0091 0.0073 0.1819
Echinococcus multilocularis lamin 0.011 0.0094 0.0094
Mycobacterium ulcerans acetyl-CoA synthetase 0.0109 0.0092 0.2147
Echinococcus granulosus retinol dehydrogenase 11 0.0039 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0109 0.0092 0.2147
Brugia malayi PAS domain containing protein 0.005 0.0029 0.0096
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0039 0.0018 0.0311
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0028 0.0094
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0062 0.0042 0.0141
Brugia malayi Protein kinase domain containing protein 0.0062 0.0042 0.0143
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0042 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0035 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0087 0.0069 0.021
Echinococcus multilocularis microtubule associated protein 2 0.42 0.4481 0.4481
Toxoplasma gondii patched family protein 0.0044 0.0023 0.0605
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Brugia malayi Patched related family protein 4 0.0044 0.0023 0.0076
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0259 0.0253 0.0565
Echinococcus granulosus beta LACTamase domain containing family member 0.0372 0.0375 0.0837
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0066 0.0223
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0259 0.0253 0.0851
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0094 0.0316
Schistosoma mansoni hypothetical protein 0.0087 0.0069 0.0153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0014 0.0046
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0001 0.0002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0007 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0378 0.0381 0.085
Brugia malayi Pre-SET motif family protein 0.0815 0.085 0.2869
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Echinococcus granulosus carbonyl reductase 1 0.0039 0.0018 0.0039
Brugia malayi AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0147 0.0495
Brugia malayi hypothetical protein 0.0044 0.0023 0.0076
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0007 0.0016
Mycobacterium ulcerans ketoacyl reductase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0277 0.0272 0.0919
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0036 0.0119
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0036 0.0099
Brugia malayi hypothetical protein 0.0166 0.0154 0.0518
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0007 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0028 0.0028
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0062 0.0042 0.113
Plasmodium vivax glycylpeptide N-tetradecanoyltransferase, putative 0.2785 0.2964 1
Entamoeba histolytica hypothetical protein 0.1017 0.1067 0.36
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0042 0.0094
Schistosoma mansoni hypothetical protein 0.1051 0.1103 0.2461
Loa Loa (eye worm) hypothetical protein 0.011 0.0094 0.0317
Entamoeba histolytica acyl-coA synthetase, putative 0.037 0.0373 0.1258
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0042 0.0143
Onchocerca volvulus 0.0372 0.0375 0.3862
Trichomonas vaginalis N-myristoyl transferase, putative 0.2785 0.2964 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0028 0.0072
Entamoeba histolytica short chain dehydrogenase family protein 0.0039 0.0018 0.0059
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0024 0.0054
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0087 0.0069 0.1494
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0094 0.0314
Loa Loa (eye worm) hypothetical protein 0.037 0.0373 0.1258
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0109 0.0092 0.2147
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0022 0.0048
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0022
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0000000052477 0.0000000052477
Plasmodium falciparum importin beta, putative 0.0029 0.0007 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0042 0.0143
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0007 0.0024
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.056 0.0577 0.1946
Schistosoma mansoni N-myristoyltransferase 0.2785 0.2964 0.6614
Brugia malayi CHD4 protein 0.0026 0.0003 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.037 0.0373 0.1258
Schistosoma mansoni survival motor neuron protein 0.0463 0.0472 0.1053
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0117 0.01 0.01
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.0042 0.0138
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Trichomonas vaginalis D-aminoacylase, putative 0.0372 0.0375 0.1265
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0006 0.0022
Brugia malayi N-terminal motif family protein 0.0379 0.0382 0.1288
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Onchocerca volvulus 0.011 0.0094 0.0968
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0015 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0013 0.003
Toxoplasma gondii patched family protein 0.0044 0.0023 0.0605
Leishmania major hypothetical protein, conserved 0.0039 0.0018 0.0057
Loa Loa (eye worm) nuclear factor I 0.0024 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0013 0.0045
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0013 0.0357
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Leishmania major 4-coumarate:coa ligase-like protein 0.037 0.0373 0.1256
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Onchocerca volvulus 0.0372 0.0375 0.3862
Loa Loa (eye worm) dehydrogenase 0.0039 0.0018 0.0059
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0028 0.0005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0087 0.0069 0.0229
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0299 0.0297 0.0297
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0063 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0073 0.0247
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0042 0.0094
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0034 0.0065
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0015 0.0033
Echinococcus granulosus importin subunit beta 1 0.0029 0.0007 0.0015
Onchocerca volvulus 0.0928 0.0971 1
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Echinococcus granulosus chromobox protein 1 0.014 0.0126 0.0281
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0147 0.0147
Brugia malayi hypothetical protein 0.0091 0.0073 0.0247
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0062 0.0042 0.0141
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0293 0.029 0.0979
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.006 0.0201
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0036 0.0121
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0013 0.0045
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0262 0.0256 0.095
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0042 0.0042
Trichomonas vaginalis steroid dehydrogenase, putative 0.0039 0.0018 0.0059
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0042 0.0042
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0007 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0727 0.0755 0.0755
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0039 0.0018 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.0114 0.0098 0.0329
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0094 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0018 0.0059
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Toxoplasma gondii hypothetical protein 0.0044 0.0023 0.0605
Trypanosoma brucei N-myristoyl transferase, putative 0.2785 0.2964 1
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0039 0.0018 0.0059
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0042 0.0094
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0007 0.0072
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0034 0.0034
Leishmania major acetyl-CoA synthetase, putative 0.0109 0.0092 0.0308
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0094 0.0316
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Plasmodium vivax patched family protein, putative 0.0044 0.0023 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0013 0.0043
Echinococcus multilocularis protein dispatched 1 0.0356 0.0357 0.0357
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0118 0.0102 0.0102
Leishmania major cathepsin L-like protease 0.0062 0.0042 0.014
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0003 0.0012
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0087 0.0069 0.1494
Echinococcus granulosus smad 0.0043 0.0022 0.0048
Echinococcus multilocularis retinol dehydrogenase 13 0.0039 0.0018 0.0018
Echinococcus multilocularis carbonyl reductase 1 0.0039 0.0018 0.0018
Onchocerca volvulus 0.0039 0.0018 0.0182
Brugia malayi oxidoreductase 0.0039 0.0018 0.0059
Mycobacterium ulcerans hypothetical protein 0.0372 0.0375 1
Mycobacterium tuberculosis Probable esterase LipL 0.0372 0.0375 0.1423
Entamoeba histolytica short chain dehydrogenase family protein 0.0039 0.0018 0.0059
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0087 0.0069 0.0229
Schistosoma mansoni carbonyl reductase 0.0039 0.0018 0.0039
Brugia malayi MH2 domain containing protein 0.0043 0.0022 0.0073
Schistosoma mansoni alpha-glucosidase 0.0137 0.0123 0.0274
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Schistosoma mansoni DNA ligase IV 0.0091 0.0073 0.0163
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0114 0.0098 0.2316
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0087 0.0069 0.1494
Echinococcus multilocularis phd:f box containing protein 0.0031 0.0009 0.0009
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0109 0.0092 0.0296
Echinococcus multilocularis expressed conserved protein 0.0683 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0118 0.0102 0.0344
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0003
Loa Loa (eye worm) cytochrome P450 0.0087 0.0069 0.0231
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0087 0.0069 0.0203
Brugia malayi nuclear receptor RXR 0.0033 0.0011 0.0036
Schistosoma mansoni hypothetical protein 0.031 0.0308 0.0688
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Trypanosoma brucei Metacaspase-4 0.0315 0.0313 0.1038
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0042 0.0094
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0065 0.0144
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0012 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Echinococcus multilocularis carbonyl reductase 1 0.0039 0.0018 0.0018
Loa Loa (eye worm) beta-lactamase 0.0372 0.0375 0.1265
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0042 0.0095
Mycobacterium leprae Probable oxidoreductase 0.0039 0.0018 0.0311
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0094 0.219
Entamoeba histolytica hypothetical protein 0.0091 0.0073 0.0247
Echinococcus multilocularis dnaJ subfamily B 0.0807 0.0841 0.0841
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0039 0.0018 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0063 0.0192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Plasmodium vivax hypothetical protein, conserved 0.0372 0.0375 0.1265
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Schistosoma mansoni caspase-3 (C14 family) 0.0833 0.0869 0.1939
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0062 0.0042 0.0121
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0042 0.0094
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0039 0.0131
Brugia malayi hypothetical protein 0.0293 0.029 0.0979
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0042 0.0042
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0042 0.0094
Trypanosoma cruzi metacaspase, putative 0.0315 0.0313 0.1055
Onchocerca volvulus 0.0293 0.029 0.2985
Mycobacterium tuberculosis Conserved protein 0.0372 0.0375 0.1423
Echinococcus granulosus caspase 3 0.0518 0.0531 0.1185
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0087 0.0069 0.1494
Mycobacterium tuberculosis Probable lipase LipD 0.0372 0.0375 0.1423
Brugia malayi Dehydrogenases, short chain protein 30 0.0039 0.0018 0.0059
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0007 0.0195
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0109 0.0092 0.2147
Onchocerca volvulus 0.0039 0.0018 0.0182
Brugia malayi ecdysone receptor 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Plasmodium vivax acetyl-CoA synthetase, putative 0.0109 0.0092 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Onchocerca volvulus 0.037 0.0373 0.384
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0315 0.0313 0.8359
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0042 0.0143
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0034 0.0065
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0031 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0063 0.0214
Echinococcus granulosus Niemann Pick C1 protein 0.1039 0.109 0.2432
Brugia malayi nuclear receptor NHR-88 0.0029 0.0007 0.0024
Loa Loa (eye worm) oxidoreductase 0.0109 0.0092 0.0311
Echinococcus multilocularis smad 0.0043 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0166 0.0154 0.0518
Brugia malayi Patched protein homolog 1 0.0044 0.0023 0.0076
Onchocerca volvulus 0.0109 0.0092 0.0948
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0039 0.0018 0.0182
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0112 0.0096 0.0214
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0039 0.0018 0.0311
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0137 0.0305
Schistosoma mansoni hypothetical protein 0.0301 0.0298 0.0665
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0013 0.0045
Toxoplasma gondii oxidoreductase, putative 0.0039 0.0018 0.047
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0042 0.0042
Schistosoma mansoni cellular tumor antigen P53 0.0308 0.0306 0.0682
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0039 0.0018 0.0039
Schistosoma mansoni coup transcription factor 0.0062 0.0042 0.0094
Brugia malayi jmjC domain containing protein 0.012 0.0104 0.035
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.1017 0.1067 0.2381
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0039 0.0018 0.0059
Trypanosoma brucei unspecified product 0.0043 0.0021 0.0049
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0109 0.0092 0.2147
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0062 0.0042 0.0141
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.022 0.0211 0.0712
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0094 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Brugia malayi MH1 domain containing protein 0.0043 0.0022 0.0073
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0013 0.0043
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0007 0.0024
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.002 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0013 0.0045
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0065 0.0144
Leishmania major oxidoreductase-like protein 0.0039 0.0018 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.0114 0.0098 0.0329
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0051 0.0031 0.0103
Plasmodium falciparum lipid/sterol:H+ symporter 0.0044 0.0023 0.0076
Mycobacterium ulcerans aldehyde dehydrogenase 0.031 0.0308 0.8129
Onchocerca volvulus 0.0039 0.0018 0.0182
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0118 0.0102 0.0102
Brugia malayi hypothetical protein 0.0044 0.0023 0.0076
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0024 0.0645
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Brugia malayi Cytochrome P450 family protein 0.0203 0.0193 0.0651
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0042 0.0143
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0042 0.0119
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0022 0.0048
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0109 0.0092 0.2147
Loa Loa (eye worm) dehydrogenase 0.0039 0.0018 0.0059
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0087 0.0069 0.1494
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0007 0.0016
Giardia lamblia CDC72 0.2785 0.2964 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0091 0.0073 0.0247
Mycobacterium tuberculosis Conserved protein 0.0372 0.0375 0.1423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Treponema pallidum DNA ligase (lig) 0.0091 0.0073 0.7673
Echinococcus granulosus cytochrome P450 2K1 0.0087 0.0069 0.0153
Schistosoma mansoni smad1 5 8 and 0.0043 0.0022 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0094 0.0316
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0031 0.0081
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0039 0.0018 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0087 0.0069 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0087 0.0069 0.0203
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0262 0.0256 0.095
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0094 0.2371
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0013 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Echinococcus granulosus Protein patched homolog 1 0.0312 0.031 0.0692
Brugia malayi hypothetical protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) latrophilin receptor protein 2 0.0299 0.0297 0.1001
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0039 0.0018 0.0035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1157 0.1217 0.4105
Brugia malayi Cytochrome P450 family protein 0.0087 0.0069 0.0231
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.0141 0.0477
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Leishmania major short chain dehydrogenase-like protein 0.0039 0.0018 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0109 0.0243
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0039 0.0018 0.0037
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0094 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.002 0.0068
Echinococcus multilocularis glycylpeptide N tetradecanoyltransferase 0.2785 0.2964 0.2964
Trypanosoma brucei short-chain dehydrogenase, putative 0.0039 0.0018 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0042 0.0119
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0087 0.0069 0.0203
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0259 0.0253 0.0851
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0063 0.0214
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0087 0.0069 0.0203
Leishmania major DNA polymerase eta, putative 0.0062 0.0042 0.0138
Trichomonas vaginalis antibiotic synthetase, putative 0.0109 0.0092 0.0311
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0299 0.0297 0.1001
Schistosoma mansoni hypothetical protein 0.0299 0.0297 0.0662
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0308 0.0306 0.1032
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0062 0.0042 0.014
Echinococcus granulosus nibrin 0.0091 0.0073 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.0387 0.0391 0.132
Echinococcus granulosus histone lysine methyltransferase setb 0.0118 0.0102 0.0228
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0007 0.0016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0042 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0042 0.0143
Echinococcus multilocularis geminin 0.1051 0.1103 0.1103
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0039 0.0018 0.047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0042 0.0143
Mycobacterium ulcerans short-chain dehydrogenase 0.0039 0.0018 0.0081
Mycobacterium ulcerans beta-lactamase 0.0372 0.0375 1
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0259 0.0253 0.0939
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0051 0.0031 0.0068
Brugia malayi phosphofructokinase 0.011 0.0094 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.006 0.0201
Echinococcus multilocularis snurportin 1 0.031 0.0308 0.0308
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0042 0.0143
Loa Loa (eye worm) patched family protein 0.0044 0.0023 0.0076
Brugia malayi Latrophilin receptor protein 2 0.0299 0.0297 0.1001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0012 0.0027
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.0042 0.0096
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0094 0.0094
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0018 0.0018
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0147 0.0147
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0028 0.0062
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0277 0.0272 0.1014
Brugia malayi Niemann-Pick C1 protein precursor 0.0727 0.0755 0.2548
Schistosoma mansoni zinc finger protein 0.0029 0.0007 0.0016
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0034 0.0076
Trypanosoma cruzi N-myristoyl transferase, putative 0.2785 0.2964 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0036 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0087 0.0069 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.0381 0.085
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0039 0.0018 0.0059
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0042 0.0143
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0039 0.0018 0.0081
Echinococcus granulosus hypothetical protein 0.0039 0.0018 0.0039
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0007 0.0016
Leishmania major hypothetical protein, conserved 0.0039 0.0018 0.0057
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0036 0.008
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0028 0.0745
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0042 0.0138
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0039 0.0018 0.0057
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0051 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Brugia malayi dehydrogenases, short chain protein 2 0.0039 0.0018 0.0059
Schistosoma mansoni DNA polymerase eta 0.0062 0.0042 0.0093
Echinococcus granulosus lysine specific demethylase 6a 0.0031 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Echinococcus granulosus mitogen activated protein kinase 3 0.0259 0.0253 0.0564
Brugia malayi hypothetical protein 0.0082 0.0063 0.0214
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.0018 0.0059
Brugia malayi DKFZp564C0469 protein 0.0091 0.0073 0.0247
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0039 0.0018 0.0039
Mycobacterium leprae conserved hypothetical protein 0.0372 0.0375 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0039 0.0018 0.0059
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0029 0.0064
Echinococcus granulosus WW domain containing oxidoreductase 0.0039 0.0018 0.0039
Brugia malayi Cell death protein 3 precursor 0.0608 0.0628 0.212
Mycobacterium ulcerans acyl-CoA synthetase 0.037 0.0373 0.994
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0033 0.0073
Onchocerca volvulus 0.0092 0.0074 0.0767
Schistosoma mansoni alpha-glucosidase 0.0137 0.0123 0.0274
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0031 0.0101
Brugia malayi latrophilin 2 splice variant baaae 0.0647 0.0669 0.2258
Schistosoma mansoni smad 0.0043 0.0022 0.0048
Mycobacterium ulcerans dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0259 0.0253 0.0833
Loa Loa (eye worm) hypothetical protein 0.0727 0.0755 0.2548
Echinococcus granulosus mitogen activated protein kinase 0.0259 0.0253 0.0564
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0109 0.0092 0.0205
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0073 0.0247
Giardia lamblia Replication factor C, subunit 1 0.0091 0.0073 0.0223
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0022 0.0048
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0028 0.0094
Trypanosoma cruzi short chain dehydrogenase, putative 0.0039 0.0018 0.0057
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0009 0.0027
Brugia malayi Calcitonin receptor-like protein seb-1 0.0946 0.099 0.3342
Onchocerca volvulus 0.0463 0.0472 0.4862
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0091 0.0073 0.1625
Leishmania major short chain dehydrogenase, putative 0.0039 0.0018 0.0057
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0039 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.0079 0.006 0.0201
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0094 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0007 0.0024
Echinococcus granulosus carbonyl reductase 1 0.0039 0.0018 0.0039
Onchocerca volvulus 0.0039 0.0018 0.0182
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0039 0.0018 0.0059
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0042 0.0094
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0087 0.0069 0.1494
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0372 0.0375 1
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0031 0.0103
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.056 0.0577 0.1946
Leishmania major 4-coumarate:coa ligase-like protein 0.037 0.0373 0.1256
Brugia malayi hypothetical protein 0.0033 0.0011 0.0036
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0091 0.0073 0.0247
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0036 0.0119
Mycobacterium ulcerans lipase LipD 0.0372 0.0375 1
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0042 0.0143
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0007 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0299 0.0297 0.0297
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0039 0.0018 0.0081
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.031 0.0308 0.1036
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Trypanosoma cruzi N-myristoyl transferase, putative 0.2785 0.2964 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0091 0.0073 0.0163
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0042 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Loa Loa (eye worm) cytochrome P450 family protein 0.0114 0.0098 0.0331
Toxoplasma gondii carbonyl reductase 1, putative 0.0039 0.0018 0.047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Onchocerca volvulus 0.0039 0.0018 0.0182
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0091 0.0073 0.0247
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0109 0.0092 0.0308
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0109 0.0092 0.2147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0042 0.0094
Echinococcus multilocularis retinol dehydrogenase 11 0.0039 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0039 0.0018 0.0057
Toxoplasma gondii ATPase, AAA family protein 0.0091 0.0073 0.1954
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0062 0.0042 0.0093
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0007 0.0024
Echinococcus granulosus JmjC domain containing protein 4 0.0031 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.0018 0.0081
Schistosoma mansoni aldehyde dehydrogenase 0.031 0.0308 0.0686
Brugia malayi hypothetical protein 0.0091 0.0073 0.0247
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0013 0.0045
Echinococcus multilocularis protein patched 0.0312 0.031 0.031
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0007 0.0025
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Trichomonas vaginalis chromobox protein, putative 0.014 0.0126 0.0425
Schistosoma mansoni cpg binding protein 0.006 0.004 0.0088
Trypanosoma brucei short-chain dehydrogenase, putative 0.0039 0.0018 0.0037
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0042 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Toxoplasma gondii aldehyde dehydrogenase 0.031 0.0308 0.8203
Brugia malayi RNA, U transporter 1 0.0083 0.0064 0.0216
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0036 0.0121
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0042 0.0436
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0036 0.0121
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) patched family protein 0.0044 0.0023 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0372 0.0375 0.1263
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0372 0.0375 0.0837
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0039 0.0018 0.0057
Mycobacterium leprae Probable lipase LipE 0.0372 0.0375 1
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0039 0.0018 0.0057
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Toxoplasma gondii cytochrome p450 superfamily protein 0.0087 0.0069 0.1828
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Schistosoma mansoni Smad4 0.0043 0.0022 0.0048
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Brugia malayi beta-lactamase 0.0372 0.0375 0.1265
Brugia malayi beta-lactamase family protein 0.0372 0.0375 0.1265
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0087 0.0069 0.1494
Loa Loa (eye worm) hypothetical protein 0.0053 0.0033 0.011
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0259 0.0253 0.0851
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi 6-phosphofructokinase 0.011 0.0094 0.0316
Echinococcus multilocularis ubiquitin specific protease 41 0.0051 0.0031 0.0031
Plasmodium falciparum replication factor C subunit 1, putative 0.0091 0.0073 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Loa Loa (eye worm) hypothetical protein 0.0277 0.0272 0.0919
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.003 0.0103
Leishmania major 3-keto-dihydrosphingosine reductase 0.0039 0.0018 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0039 0.0018 0.0039
Echinococcus granulosus dna polymerase kappa 0.0062 0.0042 0.0093
Loa Loa (eye worm) hypothetical protein 0.0382 0.0385 0.13
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0006 0.0021
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0039 0.0018 0.0039
Onchocerca volvulus 0.0023 0.0000000052477 0.000000054053
Brugia malayi MH2 domain containing protein 0.0043 0.0022 0.0073
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.8469
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0946 0.099 0.3342
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0087 0.0069 0.0203
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0013 0.0045
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0007 0.0025
Brugia malayi Retinol dehydrogenase 12 0.0039 0.0018 0.0059
Toxoplasma gondii propionate-CoA ligase 0.0109 0.0092 0.2455
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0253 0.0564
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0039 0.0018 0.0311
Schistosoma mansoni hypothetical protein 0.0301 0.0298 0.0665
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0087 0.0069 0.0203
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0042 0.0119
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0104 0.0232
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0039 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Toxoplasma gondii patched family protein 0.0044 0.0023 0.0605
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0372 0.0375 0.1265
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0109 0.0092 0.0308
Onchocerca volvulus 0.0062 0.0042 0.0436
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.047
Brugia malayi hypothetical protein 0.0044 0.0023 0.0076
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0039 0.0018 0.0057
Mycobacterium ulcerans short-chain dehydrogenase 0.0039 0.0018 0.0081
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Schistosoma mansoni hypothetical protein 0.0299 0.0297 0.0662
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0738 0.0767 0.1712
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Leishmania major cytochrome p450-like protein 0.0114 0.0098 0.0329
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.0141 0.0315
Trichomonas vaginalis penicillin-binding protein, putative 0.0372 0.0375 0.1265
Leishmania major short chain dehydrogenase/reductase, putative 0.0039 0.0018 0.0057
Trypanosoma brucei unspecified product 0.0062 0.0042 0.0119
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0087 0.0069 0.1494
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0039 0.0018 0.0059
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0051 0.0031 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0042 0.0143
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0091 0.0073 0.1954
Echinococcus granulosus caspase 8 0.0315 0.0313 0.0699
Loa Loa (eye worm) hypothetical protein 0.006 0.0039 0.0133
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Toxoplasma gondii hypothetical protein 0.0029 0.0006 0.0164
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2379 0.2528 1
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0039 0.0018 0.0018
Trypanosoma brucei short-chain dehydrogenase, putative 0.0039 0.0018 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0042 0.0143
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0073 0.0247
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0109 0.0092 0.0296
Loa Loa (eye worm) hypothetical protein 0.0608 0.0628 0.212
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0042 0.0094
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0028 0.0092
Mycobacterium leprae Conserved hypothetical protein 0.0087 0.0069 0.1691
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0087 0.0069 0.1494
Loa Loa (eye worm) hypothetical protein 0.0082 0.0063 0.0214
Echinococcus multilocularis chromobox protein 1 0.014 0.0126 0.0126
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0062 0.0042 0.0042
Onchocerca volvulus 0.0044 0.0023 0.0234
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0009 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0024 0.0082
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0028 0.0028
Brugia malayi hypothetical protein 0.227 0.241 0.8133
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0031 0.0009 0.0007
Brugia malayi jmjC domain containing protein 0.0031 0.0009 0.0029
Trypanosoma brucei glucosidase, putative 0.0035 0.0013 0.0023
Schistosoma mansoni caspase-7 (C14 family) 0.0608 0.0628 0.1402
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0372 0.0375 0.1423
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0031 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi MAP kinase sur-1 0.0259 0.0253 0.0853
Onchocerca volvulus 0.0039 0.0018 0.0182
Echinococcus multilocularis cpg binding protein 0.006 0.004 0.004
Leishmania major hypothetical protein, conserved 0.0082 0.0063 0.0212
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0042 0.0138
Echinococcus granulosus lysine specific demethylase 5A 0.012 0.0104 0.0232
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Brugia malayi Probable ClpP-like protease 0.0083 0.0065 0.0218
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0109 0.0092 0.0296
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0006 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0031 0.0101
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0013 0.0045
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0051 0.0031 0.0068
Schistosoma mansoni hypothetical protein 0.0037 0.0015 0.0033
Mycobacterium ulcerans short-chain dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0039 0.0018 0.0057
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0109 0.0092 0.0311
Leishmania major acetyl-CoA synthetase, putative 0.0109 0.0092 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Brugia malayi hypothetical protein 0.0119 0.0103 0.0349
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0011 0.0011
Brugia malayi MH1 domain containing protein 0.0043 0.0022 0.0073
Loa Loa (eye worm) acetyltransferase 0.0155 0.0141 0.0477
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Mycobacterium tuberculosis Probable hydrolase 0.0372 0.0375 0.1423
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0372 0.0375 0.1423
Echinococcus granulosus tumor protein p63 0.2104 0.2233 0.4982
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0087 0.0069 0.0203
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0039 0.0018 0.0059
Entamoeba histolytica hypothetical protein 0.0024 0.0001 0.0002
Schistosoma mansoni importin beta-1 0.0029 0.0007 0.0015
Plasmodium vivax SET domain protein, putative 0.0118 0.0102 0.0344
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0091 0.0073 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0034 0.0754
Trypanosoma brucei metacaspase MCA2 0.0315 0.0313 0.1038
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0259 0.0253 0.0853
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0094 0.0316
Giardia lamblia Short-chain dehydrogenase, putative 0.0039 0.0018 0.0035
Plasmodium falciparum protein serine/threonine kinase-1 0.0062 0.0042 0.0143
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0042 0.0042
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.0372 0.0375 0.1265
Brugia malayi AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Echinococcus granulosus steroid dehydrogenase 0.0039 0.0018 0.0039
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0042 0.0138
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0104 0.0232
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Trichomonas vaginalis esterase, putative 0.0372 0.0375 0.1265
Schistosoma mansoni intermediate filament proteins 0.011 0.0094 0.021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Echinococcus granulosus chromobox protein 1 0.014 0.0126 0.0281
Brugia malayi AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Echinococcus granulosus Smad4 0.0043 0.0022 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0028 0.0028
Mycobacterium ulcerans dehydrogenase/reductase 0.0039 0.0018 0.0081
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0007 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Brugia malayi conserved hypotetical protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0299 0.0297 0.1001
Onchocerca volvulus Protein patched homolog 0.0044 0.0023 0.0234
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0099 0.2647
Schistosoma mansoni hypothetical protein 0.0647 0.0669 0.1493
Schistosoma mansoni patched 1 0.0312 0.031 0.0692
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Schistosoma mansoni jumonji domain containing protein 0.0117 0.01 0.0224
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0315 0.0313 0.8359
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0013 0.0045
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0087 0.0069 0.0203
Loa Loa (eye worm) hypothetical protein 0.227 0.241 0.8133
Entamoeba histolytica deoxycytidyl transferase, putative 0.0062 0.0042 0.014
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0109 0.0092 0.0308
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0042 0.0094
Brugia malayi nuclear receptor NHR-67 0.0029 0.0007 0.0024
Onchocerca volvulus 0.0037 0.0015 0.0152
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0259 0.0253 0.0851
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Brugia malayi hypothetical protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0259 0.0253 0.0853
Echinococcus multilocularis mitogen activated protein kinase 0.0259 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0372 0.0375 0.0375
Entamoeba histolytica acyl-CoA synthetase, putative 0.037 0.0373 0.1258
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.006 0.0615
Loa Loa (eye worm) hypothetical protein 0.0108 0.0092 0.031
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0833 0.0869 0.0869
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0066 0.0223
Toxoplasma gondii patched family protein 0.0044 0.0023 0.0605
Schistosoma mansoni cytochrome P450 0.0087 0.0069 0.0153
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0039 0.0018 0.0059
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0062 0.0042 0.0121
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Brugia malayi isocitrate dehydrogenase 0.0049 0.0028 0.0094
Loa Loa (eye worm) hypothetical protein 0.0379 0.0382 0.1288
Leishmania major 4-coumarate:coa ligase-like protein 0.037 0.0373 0.1256
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Brugia malayi ecdysteroid receptor 0.0062 0.0042 0.0143
Brugia malayi AMP-binding enzyme family protein 0.037 0.0373 0.1258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0262 0.0256 0.095
Schistosoma mansoni carbonyl reductase 0.0039 0.0018 0.0039
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0042 0.0143
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Schistosoma mansoni hypothetical protein 0.0463 0.0472 0.1053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0259 0.0253 0.6623
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0117 0.01 0.0224
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0087 0.0069 0.1494
Schistosoma mansoni acetyl-CoA synthetase 0.0109 0.0092 0.0205
Schistosoma mansoni hypothetical protein 0.0299 0.0297 0.0662
Echinococcus granulosus snurportin 1 0.031 0.0308 0.0688
Entamoeba histolytica hypothetical protein 0.1017 0.1067 0.36
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0036 0.0122
Trypanosoma cruzi FHA domain containing protein, putative 0.0091 0.0073 0.0245
Echinococcus granulosus dna polymerase eta 0.0062 0.0042 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Entamoeba histolytica glycylpeptide N-tetradecanoyltransferase, putative 0.2785 0.2964 1
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0063 0.0214
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0463 0.0472 0.1593
Schistosoma mansoni microtubule-associated protein tau 0.42 0.4481 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Echinococcus multilocularis 0.0087 0.0069 0.0069
Brugia malayi Patched related family protein 12 0.0044 0.0023 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0042 0.0143
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0039 0.0018 0.047
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0039 0.0018 0.0182
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.037 0.0373 0.994
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0007 0.0025
Entamoeba histolytica hypothetical protein 0.1017 0.1067 0.36
Onchocerca volvulus 0.0044 0.0023 0.0234
Schistosoma mansoni ap endonuclease 0.0056 0.0036 0.008
Brugia malayi hypoxia-induced factor 1 0.0153 0.014 0.0472
Echinococcus granulosus carbonyl reductase 1 0.0039 0.0018 0.0039
Leishmania major cytochrome p450-like protein 0.0087 0.0069 0.0229
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0042 0.0094
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Conserved protein 0.0372 0.0375 0.1423
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0007 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0087 0.0069 0.0203
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.037 0.0373 0.9941
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0109 0.0092 0.0289
Brugia malayi topoisomerase 0.0091 0.0073 0.0247
Schistosoma mansoni aldehyde dehydrogenase 0.031 0.0308 0.0686
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0042 0.0143
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0036 0.0121
Schistosoma mansoni cpg binding protein 0.006 0.004 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0042 0.0042
Schistosoma mansoni alpha glucosidase 0.0035 0.0013 0.003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0118 0.0102 0.272
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0028 0.0028
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Plasmodium vivax acyl-CoA synthetase, putative 0.0277 0.0272 0.0919
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.031 0.0308 0.0308
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0009 0.0029
Entamoeba histolytica hypothetical protein 0.0039 0.0018 0.0059
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0063 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0035 0.0118
Schistosoma mansoni retinal dehydrogenase 0.0039 0.0018 0.0039
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0042 0.0143
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0091 0.0073 0.0245
Echinococcus granulosus lamin 0.011 0.0094 0.021
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0024 0.0645
Toxoplasma gondii oxidoreductase, putative 0.0039 0.0018 0.047
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0372 0.0375 0.1265
Mycobacterium ulcerans acyl-CoA synthetase 0.037 0.0373 0.994
Mycobacterium ulcerans short-chain type oxidoreductase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0119 0.0103 0.0349
Onchocerca volvulus 0.0039 0.0018 0.0182
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0378 0.0381 0.1286
Brugia malayi Pre-SET motif family protein 0.0118 0.0102 0.0344
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0259 0.0253 0.6623
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0109 0.0092 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.037 0.0373 0.1415
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0042 0.0143
Trypanosoma cruzi metacaspase 5, putative 0.0315 0.0313 0.1055
Loa Loa (eye worm) transcription factor SMAD2 0.0632 0.0654 0.2205
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.037 0.0373 0.994
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.1389
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0036 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0312 0.031 0.1046
Mycobacterium ulcerans ketoacyl reductase 0.0039 0.0018 0.0081
Brugia malayi dehydrogenases, short chain protein 9 0.0039 0.0018 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0253 0.0853
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0087 0.0069 0.0203
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0253 0.0853
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0091 0.0073 0.0247
Brugia malayi AMP-binding enzyme family protein 0.037 0.0373 0.1258
Echinococcus multilocularis replication factor c subunit 1 0.0091 0.0073 0.0073
Schistosoma mansoni carbonyl reductase 0.0039 0.0018 0.0039
Brugia malayi jmjC domain containing protein 0.0031 0.0009 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0042 0.0143
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0109 0.0092 0.0311
Onchocerca volvulus Glucosylceramidase homolog 0.0368 0.037 0.381
Onchocerca volvulus 0.0039 0.0018 0.0182
Brugia malayi tailless protein 0.0029 0.0007 0.0024
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0277 0.0272 1
Echinococcus multilocularis caspase 2 0.0608 0.0628 0.0628
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0109 0.0092 0.0092
Echinococcus granulosus hypothetical protein 0.006 0.0039 0.0088
Echinococcus granulosus lamin dm0 0.011 0.0094 0.021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0042 0.0747
Trichomonas vaginalis penicillin-binding protein, putative 0.0372 0.0375 0.1265
Plasmodium vivax JmjC domain containing protein 0.0031 0.0009 0.0029
Schistosoma mansoni single-minded 0.005 0.0029 0.0064
Echinococcus multilocularis steroid dehydrogenase 0.0039 0.0018 0.0018
Echinococcus granulosus microtubule associated protein 2 0.42 0.4481 1
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Brugia malayi N-myristoyltransferase 2 0.2785 0.2964 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0011 0.0036
Brugia malayi MH1 domain containing protein 0.0024 0.0001 0.0003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0036 0.0097
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0379 0.0382 0.3931
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0042 0.0094
Trypanosoma brucei metacaspase 5, putative 0.0315 0.0313 0.1038
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0042 0.0042
Trypanosoma brucei cytochrome P450, putative 0.0114 0.0098 0.031
Onchocerca volvulus Sepiapterin reductase homolog 0.0039 0.0018 0.0182
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0007 0.0007
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0039 0.0018 0.0037
Echinococcus multilocularis survival motor neuron protein 1 0.227 0.241 0.241
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0024 0.0082
Onchocerca volvulus 0.0109 0.0092 0.0948
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Echinococcus granulosus dnaJ subfamily B 0.0807 0.0841 0.1877
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0001 0.0002
Leishmania major short chain dehydrogenase, putative 0.0039 0.0018 0.0057
Mycobacterium tuberculosis Probable lipase LipE 0.0372 0.0375 0.1423
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Schistosoma mansoni hypothetical protein 0.1017 0.1067 0.2381
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0007 0.0007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0372 0.0375 0.1423
Trichomonas vaginalis D-aminoacylase, putative 0.0372 0.0375 0.1265
Echinococcus granulosus replication factor c subunit 1 0.0091 0.0073 0.0163
Echinococcus multilocularis JmjC domain containing protein 4 0.0031 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Giardia lamblia Kinase, CMGC MAPK 0.0259 0.0253 0.083
Echinococcus granulosus geminin 0.1051 0.1103 0.2461
Brugia malayi nuclear hormone receptor 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0029
Echinococcus granulosus cpg binding protein 0.006 0.004 0.0088
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0015 0.005
Echinococcus granulosus Niemann Pick C1 protein 0.0727 0.0755 0.1685
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0028 0.0094
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0036 0.3284
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0036 0.0121
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.014
Brugia malayi Heterochromatin protein 1 0.014 0.0126 0.0425
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Schistosoma mansoni topbp1 0.0091 0.0073 0.0163
Schistosoma mansoni hypothetical protein 0.0299 0.0297 0.0662
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0109 0.0092 0.0296
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0378 0.0381 0.0381
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0031 0.0009 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.0018 0.0059
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0087 0.0069 0.0203
Echinococcus granulosus GPCR family 2 0.0299 0.0297 0.0662
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0007 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0039 0.0018 0.0037
Echinococcus granulosus carbonyl reductase 1 0.0039 0.0018 0.0039
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0042 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0109 0.0092 0.0311
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0042 0.014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0028 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0029
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0042 0.0094
Echinococcus multilocularis retinol dehydrogenase 11 0.0039 0.0018 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Brugia malayi hypothetical protein 0.0053 0.0032 0.0109
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0087 0.0069 0.0203
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0087 0.0069 0.1494
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0042 0.0436
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0087 0.0069 0.1494
Loa Loa (eye worm) hypothetical protein 0.0083 0.0065 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0073 0.0245
Onchocerca volvulus 0.0062 0.0041 0.0427
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0007 0.0175
Brugia malayi Cytochrome P450 family protein 0.0114 0.0098 0.0331
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0042 0.014
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0039 0.0018 0.0039
Onchocerca volvulus 0.0044 0.0023 0.0234
Leishmania major DNA polymerase kappa, putative 0.0062 0.0042 0.0138
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0109 0.0092 0.2147
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Plasmodium falciparum JmjC domain-containing protein, putative 0.0031 0.0009 0.0029
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Echinococcus multilocularis chromobox protein 1 0.014 0.0126 0.0126
Echinococcus multilocularis caspase 8 0.0315 0.0313 0.0313
Trypanosoma cruzi short chain dehydrogenase, putative 0.0039 0.0018 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0104 0.035
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) patched family protein 0.0044 0.0023 0.0076
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0028 0.0094
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0094 0.0317
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0259 0.0253 0.0253
Echinococcus multilocularis musashi 0.011 0.0094 0.0094
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0013 0.0045
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0065 0.1588
Echinococcus multilocularis dna polymerase eta 0.0062 0.0042 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0727 0.0755 0.2548
Loa Loa (eye worm) MH2 domain-containing protein 0.0632 0.0654 0.2205
Loa Loa (eye worm) hypothetical protein 0.0315 0.0313 0.1057
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0007 0.0024
Brugia malayi intermediate filament protein 0.011 0.0094 0.0317
Loa Loa (eye worm) intermediate filament protein 0.011 0.0094 0.0317
Trypanosoma cruzi metacaspase 5, putative 0.0315 0.0313 0.1055
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0042 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0253 0.0853
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0042 0.0747
Trypanosoma cruzi metacaspase, putative 0.0315 0.0313 0.1055
Onchocerca volvulus 0.0044 0.0023 0.0234
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0259 0.0253 0.0855
Giardia lamblia Kinase, CMGC CLK 0.0062 0.0042 0.0119
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0039 0.0018 0.0037
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0013 0.0045
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0033 0.0033
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0015 0.0015
Onchocerca volvulus Protein patched homolog 0.0044 0.0023 0.0234
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Schistosoma mansoni nuclear receptor 0.0029 0.0007 0.0016
Schistosoma mansoni transcription factor LCR-F1 0.1017 0.1067 0.2381
Echinococcus multilocularis sterol regulatory element binding protein 0.0312 0.031 0.031
Trichomonas vaginalis set domain proteins, putative 0.0928 0.0971 0.3276
Echinococcus multilocularis lamin dm0 0.011 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Mycobacterium ulcerans oxidoreductase 0.0039 0.0018 0.0081
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0109 0.0092 0.2147
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0039 0.0018 0.0057
Mycobacterium ulcerans esterase/lipase LipP 0.0372 0.0375 1
Echinococcus granulosus single minded 2 0.0037 0.0015 0.0033
Leishmania major dehydrogenase-like protein 0.0039 0.0018 0.0057
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0062 0.0042 0.0141
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0091 0.0073 0.0247
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Onchocerca volvulus 0.0057 0.0036 0.0373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0042 0.0042
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0109 0.0092 0.0296
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0014 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0102 0.0228
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0028 0.0028
Plasmodium falciparum steroid dehydrogenase, putative 0.0039 0.0018 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0087 0.0069 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0042 0.0143
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0042 0.0143
Schistosoma mansoni phosphatidylserine receptor 0.0031 0.0009 0.0019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Leishmania major hypothetical protein, conserved 0.0039 0.0018 0.0057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Brugia malayi CXXC zinc finger family protein 0.0057 0.0036 0.0122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0062 0.0042 0.0096
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0022 0.0073
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.031 0.0308 0.0686
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Trypanosoma brucei oxidoreductase-like protein 0.0039 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Leishmania major pteridine reductase 1 0.0039 0.0018 0.0057
Echinococcus multilocularis GPCR, family 2 0.0299 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0372 0.0375 0.1265
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0007 0.0195
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.6699
Loa Loa (eye worm) cytochrome P450 family protein 0.0203 0.0193 0.0651
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0109 0.0092 0.2455
Onchocerca volvulus Cell death protein 3 homolog 0.0608 0.0628 0.6471
Plasmodium vivax steroid dehydrogenase, putative 0.0039 0.0018 0.0059
Loa Loa (eye worm) patched family protein 0.0044 0.0023 0.0076
Mycobacterium leprae putative cytochrome p450 0.0087 0.0069 0.1691
Brugia malayi hypothetical protein 0.1017 0.1067 0.36
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0094 0.0209
Brugia malayi Cytochrome P450 family protein 0.0114 0.0098 0.0331
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0039 0.0131
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0109 0.0092 0.2329
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0039 0.0018 0.0059
Brugia malayi Dehydrogenases, short chain protein 2 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.037 0.0373 0.1258
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.047
Loa Loa (eye worm) hypothetical protein 0.0091 0.0073 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.002 0.0043
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0028 0.0072
Brugia malayi MH2 domain containing protein 0.0632 0.0654 0.2205
Trypanosoma brucei metacaspase 0.0315 0.0313 0.1038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0094 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.037 0.0373 0.994
Loa Loa (eye worm) hypothetical protein 0.037 0.0373 0.1258
Echinococcus multilocularis oxidoreductase 0.0039 0.0018 0.0018
Onchocerca volvulus 0.0372 0.0375 0.3862
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0378 0.0381 0.085
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0109 0.0092 0.0289
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0299 0.0297 0.0662
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0065 0.0065
Echinococcus granulosus jumonji domain containing 1A 0.0031 0.0009 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Brugia malayi hypothetical protein 0.0039 0.0018 0.0059
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0299 0.0297 0.0662
Loa Loa (eye worm) hypothetical protein 0.0119 0.0103 0.0349
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0039 0.0018 0.0059
Brugia malayi Patched related family protein 10 0.0044 0.0023 0.0076
Onchocerca volvulus 0.0293 0.029 0.2989
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0372 0.0375 0.0837
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0141 0.0127 0.0283
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0277 0.0272 0.7151
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0259 0.0253 0.0851
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0011 0.0036
Schistosoma mansoni chromobox protein 0.014 0.0126 0.0281
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0042 0.014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0042 0.0094
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0833 0.0869 0.1939
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Leishmania major cathepsin L-like protease 0.0062 0.0042 0.014
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0039 0.0018 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0087 0.0069 0.0203
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0109 0.0092 0.2329
Toxoplasma gondii exonuclease III APE 0.0056 0.0036 0.0957
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Trypanosoma brucei protein kinase, putative 0.0259 0.0253 0.0833
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Onchocerca volvulus 0.0148 0.0134 0.1383
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0102 0.0228
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0028 0.0062
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0946 0.099 0.3342
Schistosoma mansoni jumonji domain containing protein 0.0031 0.0009 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0094 0.0316
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0109 0.0092 0.0311
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0039 0.0018 0.047
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0091 0.0073 0.0247
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0946 0.099 0.3342
Echinococcus multilocularis nibrin 0.0091 0.0073 0.0073
Onchocerca volvulus 0.0039 0.0018 0.0182
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0036
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0007 0.0195
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0021 0.0049
Loa Loa (eye worm) patched family protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Echinococcus granulosus expressed conserved protein 0.0683 0.0708 0.158
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0315 0.0313 0.1057
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0378 0.0381 0.1286
Brugia malayi Myosin head containing protein 0.0044 0.0023 0.0076
Schistosoma mansoni ap endonuclease 0.0056 0.0036 0.008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0039 0.0018 0.0182
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0013 0.0045
Brugia malayi jmjC domain containing protein 0.0031 0.0009 0.0029
Trypanosoma brucei unspecified product 0.0043 0.0021 0.0049
Brugia malayi cytochrome P450 0.0087 0.0069 0.0231
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0073 0.0245
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0051 0.0031 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0051 0.0031 0.0068
Plasmodium falciparum acyl-CoA synthetase 0.0277 0.0272 0.0919
Entamoeba histolytica hypothetical protein 0.1017 0.1067 0.36
Brugia malayi nuclear receptor NHR-88 0.0062 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0109 0.0092 0.0296
Leishmania major hypothetical protein, conserved 0.0039 0.0018 0.0057
Loa Loa (eye worm) heterochromatin protein 1 0.014 0.0126 0.0425
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0087 0.0069 0.1494
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.2167
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Onchocerca volvulus 0.0308 0.0306 0.3149
Loa Loa (eye worm) hypothetical protein 0.0647 0.0669 0.2258
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0042 0.014
Schistosoma mansoni phd/f-box containing protein 0.0031 0.0009 0.0019
Onchocerca volvulus 0.0039 0.0018 0.0182
Leishmania major protein kinase, putative 0.0062 0.0042 0.0141
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0051 0.0031 0.0031
Brugia malayi chromobox protein homolog 3 0.0079 0.006 0.0201
Onchocerca volvulus Huntingtin homolog 0.0119 0.0103 0.1065
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0063 0.169
Brugia malayi Pax transcription activation domain interacting protein 0.0091 0.0073 0.0247
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.014 0.0472
Echinococcus multilocularis Smad4 0.0043 0.0022 0.0022
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0039 0.0018 0.0018
Brugia malayi hypothetical protein 0.0033 0.0011 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0372 0.0375 0.1246
Mycobacterium ulcerans ketoacyl reductase 0.0039 0.0018 0.0081
Onchocerca volvulus 0.0044 0.0023 0.0234
Loa Loa (eye worm) CYP4Cod1 0.0114 0.0098 0.0331
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0066 0.0681
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0315 0.0313 0.1057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0042 0.0094
Loa Loa (eye worm) cytochrome P450 family protein 0.0114 0.0098 0.0331
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0039 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0027 0.0004 0.0011
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0007 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0028 0.0041
Leishmania major metacaspase, putative 0.0315 0.0313 0.1055
Schistosoma mansoni smad1 5 8 and 0.0043 0.0022 0.0048
Loa Loa (eye worm) Smad1 0.0043 0.0022 0.0073
Echinococcus granulosus glycylpeptide N tetradecanoyltransferase 0.2785 0.2964 0.6614
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0087 0.0069 0.0203
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0087 0.0069 0.1494
Brugia malayi steroid hormone receptor 0.0062 0.0042 0.0143
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0007 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0013 0.0043
Echinococcus granulosus survival motor neuron protein 1 0.227 0.241 0.5379
Loa Loa (eye worm) hypothetical protein 0.0109 0.0092 0.0311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0022 0.0022
Leishmania major protein kinase, putative 0.0024 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0301 0.0298 0.0665
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.0059
Trypanosoma brucei short-chain dehydrogenase, putative 0.0039 0.0018 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0378 0.0381 0.0381
Giardia lamblia DINP protein human, muc B family 0.0062 0.0042 0.0116
Brugia malayi hypothetical protein 0.0029 0.0007 0.0024
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0087 0.0069 0.1494
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0036 0.0588
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0065 0.1727
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0073 0.0247
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0065 0.1389
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0143
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0009 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0046
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0007 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0042 0.0143
Onchocerca volvulus 0.0091 0.0073 0.0755
Trypanosoma brucei metacaspase MCA3 0.0315 0.0313 0.1038
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0018 0.0057
Brugia malayi follicle stimulating hormone receptor 0.1157 0.1217 0.4105
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0087 0.0069 0.1494
Onchocerca volvulus 0.0141 0.0127 0.1304
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0039 0.0018 0.0059
Echinococcus multilocularis apoptotic protease activating factor 1 0.0293 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0277 0.0272 0.0919
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0312 0.031 0.1046
Brugia malayi AMP-binding enzyme family protein 0.037 0.0373 0.1258
Plasmodium vivax replication factor C subunit 1, putative 0.0091 0.0073 0.0247
Schistosoma mansoni lamin 0.011 0.0094 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Trichomonas vaginalis glucosylceramidase, putative 0.0368 0.037 0.1248
Brugia malayi 6-phosphofructokinase 0.011 0.0094 0.0316
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0018 0.047
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0021 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0009 0.0029
Trypanosoma cruzi metacaspase, putative 0.0315 0.0313 0.1055
Echinococcus granulosus phd:f box containing protein 0.0031 0.0009 0.0019
Onchocerca volvulus 0.0039 0.0018 0.0182
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Echinococcus multilocularis lysine specific demethylase 5A 0.0117 0.01 0.01
Brugia malayi beta-lactamase family protein 0.0372 0.0375 0.1265
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0051 0.0031 0.0079
Schistosoma mansoni cpg binding protein 0.0057 0.0036 0.0081
Giardia lamblia Hypothetical protein 0.0039 0.0018 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0042 0.0143
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0094 0.0209
Schistosoma mansoni terminal deoxycytidyl transferase 0.0062 0.0042 0.0093
Brugia malayi nuclear receptor RXR 0.0029 0.0007 0.0024
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0007 0.0072
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Leishmania major hypothetical protein, conserved 0.0039 0.0018 0.0057
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0313 0.1057
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Leishmania major hypothetical protein, conserved 0.0031 0.0009 0.0027
Onchocerca volvulus 0.0109 0.0092 0.0948
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0007 0.0016
Leishmania major quinonoid dihydropteridine reductase 0.0039 0.0018 0.0057
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0007 0.0016
Echinococcus multilocularis 0.006 0.0039 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0087 0.0069 0.0203
Brugia malayi CHE-14 protein 0.0312 0.031 0.1046
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0031 0.0009 0.0232
Schistosoma mansoni chromobox protein 0.014 0.0126 0.0281
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0062 0.0042 0.0143
Onchocerca volvulus 0.0039 0.0018 0.0182
Mycobacterium ulcerans short-chain dehydrogenase 0.0039 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0051 0.003 0.0103
Loa Loa (eye worm) hypothetical protein 0.0312 0.031 0.1046
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0042 0.0119
Loa Loa (eye worm) hypothetical protein 0.0293 0.029 0.0978
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0109 0.0092 0.0308
Trichomonas vaginalis antibiotic synthetase, putative 0.0109 0.0092 0.0311
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0062 0.0042 0.0093
Brugia malayi hypothetical protein 0.0293 0.029 0.0978
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0109 0.0092 0.0296
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) N-myristoyltransferase 2 0.2785 0.2964 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0315 0.0313 0.0699
Brugia malayi Smad1 0.0043 0.0022 0.0073
Echinococcus granulosus caspase 2 0.0608 0.0628 0.1402
Mycobacterium ulcerans carveol-like dehydrogenase 0.0039 0.0018 0.0081
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0039 0.0018 0.0057
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0042 0.0094
Schistosoma mansoni steroid dehydrogenase 0.0039 0.0018 0.0039
Trypanosoma cruzi metacaspase, putative 0.0315 0.0313 0.1055
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0087 0.0069 0.0229
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0815 0.085 0.2869
Schistosoma mansoni protein phosphatase 2C 0.0031 0.0009 0.0019
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0311
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Echinococcus multilocularis lysine specific demethylase 6a 0.0031 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0807 0.0841 0.1877
Plasmodium vivax metacaspase 1, putative 0.0315 0.0313 0.1057
Brugia malayi jmjC domain containing protein 0.0031 0.0009 0.0029
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.037 0.0373 0.994
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0024 0.0082
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0315 0.0313 0.8359
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0042 0.0119
Onchocerca volvulus 0.0029 0.0007 0.0072
Onchocerca volvulus 0.0044 0.0023 0.0234
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0039 0.0018 0.0057
Onchocerca volvulus 0.011 0.0094 0.0968
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0065 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.056 0.0577 0.1946
Echinococcus multilocularis caspase 0.0833 0.0869 0.0869
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0007 0.0007
Brugia malayi SET domain containing protein 0.0028 0.0006 0.002
Leishmania major cathepsin L-like protease 0.0062 0.0042 0.014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0011 0.0036
Echinococcus multilocularis conserved hypothetical protein 0.0039 0.0018 0.0018
Echinococcus multilocularis mitogen activated protein kinase 3 0.0259 0.0253 0.0253
Trichomonas vaginalis replication factor C large subunit, putative 0.0091 0.0073 0.0247
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0094 0.0209
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Echinococcus multilocularis tumor protein p63 0.2104 0.2233 0.2233
Loa Loa (eye worm) phosphofructokinase 0.011 0.0094 0.0316
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0036 0.0121
Schistosoma mansoni hypothetical protein 0.1051 0.1103 0.2461
Echinococcus multilocularis caspase 3 0.0518 0.0531 0.0531
Schistosoma mansoni nuclear receptor 0.0029 0.0007 0.0016
Leishmania major N-myristoyl transferase, putative 0.2785 0.2964 1
Trypanosoma brucei N-myristoyltransferase 0.2785 0.2964 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0042 0.014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Brugia malayi hypothetical protein 0.0044 0.0023 0.0076
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0051 0.0031 0.0103
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0094 0.0317
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0039 0.0018 0.0057
Brugia malayi protein C24B5.3 0.0044 0.0023 0.0076
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0036 0.012
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0087 0.0069 0.1494
Mycobacterium ulcerans acyl-CoA synthetase 0.0109 0.0092 0.2147
Echinococcus granulosus intermediate filament protein 0.011 0.0094 0.021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0007 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0372 0.0375 0.1263
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0039 0.0018 0.0039
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0311
Mycobacterium ulcerans oxidoreductase 0.0039 0.0018 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0042 0.0095
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0007 0.0016
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.0018 0.0081
Mycobacterium ulcerans aldehyde dehydrogenase 0.031 0.0308 0.8129
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0042 0.0042
Mycobacterium ulcerans aldehyde dehydrogenase 0.031 0.0308 0.8129
Echinococcus granulosus dual specificity protein kinase clk2 0.0062 0.0042 0.0095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0059
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0094 0.0314
Trichomonas vaginalis glucosylceramidase, putative 0.0387 0.0391 0.132
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0028 0.0092
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0007 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Brugia malayi Importin beta-1 subunit 0.0029 0.0007 0.0022
Brugia malayi Patched family protein 0.0044 0.0023 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0007 0.0025
Plasmodium falciparum glycylpeptide N-tetradecanoyltransferase 0.2785 0.2964 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0262 0.0256 0.095
Echinococcus multilocularis jumonji domain containing 1A 0.0031 0.0009 0.0009
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0042 0.0094
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.1017 0.1067 0.1067
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0091 0.0073 0.0226
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0102 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0073 0.0247
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0042 0.014
Schistosoma mansoni topbp1 0.0091 0.0073 0.0163
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0042 0.0094
Schistosoma mansoni short chain dehydrogenase 0.0039 0.0018 0.0039
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0259 0.0253 0.0851
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0036
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0001 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0028 0.0745
Plasmodium falciparum metacaspase-like protein 0.0315 0.0313 0.1057
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0253 0.0853
Leishmania major cytochrome p450-like protein 0.0087 0.0069 0.0229
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0031 0.0009 0.0232
Echinococcus granulosus ubiquitin specific protease 41 0.0051 0.0031 0.0068
Leishmania major short chain dehydrogenase/reductase, putative 0.0039 0.0018 0.0057
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0087 0.0069 0.1494
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.0018 0.0081
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0109 0.0092 0.2329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0042 0.012
Onchocerca volvulus 0.0029 0.0007 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0313 0.1057
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0003 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0042 0.0138
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0087 0.0069 0.1494
Loa Loa (eye worm) hypothetical protein 0.0044 0.0023 0.0076
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0109 0.0092 0.0311
Echinococcus granulosus apoptotic protease activating factor 1 0.0293 0.029 0.0648
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0087 0.0069 0.0203
Leishmania major pantothenate kinase subunit, putative 0.0027 0.0004 0.0011
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0094 0.0294
Leishmania major hypothetical protein, conserved 0.0372 0.0375 0.1263
Loa Loa (eye worm) oxidoreductase 0.0039 0.0018 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.0381 0.085
Loa Loa (eye worm) hypothetical protein 0.0277 0.0272 0.0919
Leishmania major protein kinase, putative 0.0062 0.0042 0.0141
Schistosoma mansoni lamin 0.011 0.0094 0.021
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0109 0.0092 0.2455
Echinococcus multilocularis carbonyl reductase 1 0.0039 0.0018 0.0018
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0259 0.0253 0.6742
Echinococcus multilocularis dual specificity protein kinase clk2 0.0062 0.0042 0.0042
Plasmodium falciparum metacaspase 1 0.0315 0.0313 0.1057
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.0308 0.104
Schistosoma mansoni hypothetical protein 0.0293 0.029 0.0648
Onchocerca volvulus 0.0044 0.0023 0.0234
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0076 0.0232
Trypanosoma brucei short-chain dehydrogenase, putative 0.0039 0.0018 0.0037
Giardia lamblia Reductase, putative 0.0039 0.0018 0.0035
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0039 0.0018 0.0059
Trichomonas vaginalis N-myristoyl transferase, putative 0.183 0.1939 0.6542
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0022 0.0022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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