Detailed information for compound 1346429

Basic information

Technical information
  • TDR Targets ID: 1346429
  • Name: 3-(2,3-dihydro-1H-inden-5-yloxymethyl)benzohy drazide
  • MW: 282.337 | Formula: C17H18N2O2
  • H donors: 2 H acceptors: 1 LogP: 2.75 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: NNC(=O)c1cccc(c1)COc1ccc2c(c1)CCC2
  • InChi: 1S/C17H18N2O2/c18-19-17(20)15-6-1-3-12(9-15)11-21-16-8-7-13-4-2-5-14(13)10-16/h1,3,6-10H,2,4-5,11,18H2,(H,19,20)
  • InChiKey: QWQKOQFUSUKFQR-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 3-(indan-5-yloxymethyl)benzohydrazide
  • 3-(5-indanyloxymethyl)benzohydrazide
  • 3-(Indan-5-yloxymethyl)-benzoic acid hydrazide
  • MLS000591082
  • SMR000217878
  • STK052020
  • Oprea1_121143
  • ZINC00522808

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 0.0087 0.0455 0.052
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0208 0.0238
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Trypanosoma cruzi rac serine-threonine kinase, putative 0.004 0.0025 0.0077
Brugia malayi Protein kinase domain containing protein 0.032 0.2624 0.4544
Trichomonas vaginalis TKL family protein kinase 0.0038 0.0007 0.000000041062
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0232 0.1805 0.3123
Toxoplasma gondii casein kinase I 0.0114 0.0712 0.2792
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0455 0.1714
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0712 0.1569
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0164 0.1174 0.4932
Echinococcus multilocularis netrin receptor unc 5 0.004 0.0026 0.003
Schistosoma mansoni hypothetical protein 0.0059 0.0198 0.0425
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0041 0.0036 0.006
Loa Loa (eye worm) hypothetical protein 0.0077 0.037 0.064
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0375 0.1405
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0375 0.1405
Plasmodium falciparum calcium-dependent protein kinase 5 0.0114 0.0709 0.5859
Echinococcus multilocularis Zinc finger, DBF type 0.0507 0.4369 0.4986
Brugia malayi Calcitonin receptor-like protein seb-1 0.0186 0.1382 0.2387
Echinococcus granulosus casein kinase i 0.0114 0.0712 0.0712
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.1042 0.1798
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0259 0.2059 0.8667
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0455 0.1714
Trichomonas vaginalis AGC family protein kinase 0.004 0.0025 0.007
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0038 0.0007 0.001
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0071 0.0313 0.0541
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0434 0.3686 0.4206
Entamoeba histolytica protein kinase, putative 0.0084 0.0432 0.1625
Loa Loa (eye worm) hypothetical protein 0.0045 0.0069 0.0117
Echinococcus granulosus tyrosine protein kinase Blk 0.0196 0.147 0.147
Loa Loa (eye worm) AGC/PKN protein kinase 0.0316 0.2593 0.4497
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0044 0.0058 0.0058
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0087 0.0455 0.1895
Plasmodium falciparum calcium-dependent protein kinase 2 0.0114 0.0709 0.5859
Loa Loa (eye worm) serine/threonine protein kinase 0.0038 0.0007 0.001
Onchocerca volvulus 0.0093 0.0517 0.1589
Schistosoma mansoni tyrosine kinase 0.0203 0.1541 0.3414
Giardia lamblia Kinase, PLK 0.0293 0.2374 1
Echinococcus granulosus Immunoglobulin 0.0069 0.0292 0.0292
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0332 0.2736 0.4745
Echinococcus granulosus calcium activated potassium channel 0.0109 0.0667 0.0667
Echinococcus granulosus tyrosine protein kinase Src42A 0.0159 0.1133 0.1133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0056 0.0173 0.0289
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0126 0.082 0.3434
Echinococcus multilocularis serine:threonine protein kinase 0.0075 0.035 0.04
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis tensin 0.006 0.0208 0.0238
Schistosoma mansoni tyrosine kinase 0.0334 0.2761 0.6129
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0075 0.0259
Loa Loa (eye worm) RasGEF domain-containing protein 0.0041 0.0036 0.006
Giardia lamblia Kinase, CAMK CAMKL 0.008 0.0398 0.165
Echinococcus granulosus fch and double sh3 domains protein 2 0.0039 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.049 0.4208 0.7295
Brugia malayi serine/threonine-protein kinase plk-2 0.0293 0.2374 0.4111
Brugia malayi Furin-like cysteine rich region family protein 0.0203 0.1541 0.2663
Brugia malayi protein-tyrosine kinase 0.0196 0.147 0.254
Brugia malayi cytokine inducible SH2-containing protein 5 0.006 0.0208 0.035
Schistosoma mansoni hypothetical protein 0.0056 0.0169 0.0361
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0038 0.0007 0.0008
Plasmodium vivax tyrosine kinase-like protein, putative 0.0084 0.0427 0.3509
Echinococcus granulosus dual specificity 0.0089 0.0478 0.0478
Echinococcus multilocularis Glutaredoxin protein 5 0.0137 0.0922 0.1052
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Echinococcus multilocularis dual specificity 0.0129 0.0851 0.0972
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0088 0.0465 0.175
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0087 0.0455 0.1714
Echinococcus multilocularis cyclin dependent kinase 0.0078 0.0375 0.0427
Trypanosoma cruzi cdc2-related kinase 1 0.0078 0.0375 0.1553
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.005 0.0116 0.0416
Echinococcus multilocularis serine:threonine protein kinase N2 0.0316 0.2593 0.296
Echinococcus granulosus SH2 domain containing adapter protein F 0.006 0.0208 0.0208
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.008 0.0398 0.1493
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0114 0.0709 0.1219
Echinococcus granulosus cyclin dependent kinase 5 0.0078 0.0375 0.0375
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0084 0.0427 0.3509
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.004 0.0025 0.007
Loa Loa (eye worm) TK/FER protein kinase 0.0434 0.3686 0.6392
Loa Loa (eye worm) hypothetical protein 0.027 0.2158 0.3741
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0144 0.0994 0.8242
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0075 0.0259
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Schistosoma mansoni tyrosine kinase 0.0132 0.0881 0.1946
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0173 0.126 0.126
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0116 0.0727 0.1259
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0059 0.0198 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Echinococcus multilocularis FL cytokine receptor 0.0038 0.0007 0.0008
Schistosoma mansoni protein kinase subunit beta 0.0126 0.082 0.1809
Loa Loa (eye worm) RGC/RGC protein kinase 0.0038 0.0007 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0075 0.0269
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Onchocerca volvulus 0.0056 0.0173 0.0518
Onchocerca volvulus 0.0038 0.0007 0.000000033436
Loa Loa (eye worm) hypothetical protein 0.0099 0.0568 0.0984
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0553 0.0631
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0098 0.0565 0.0645
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0039 0.0009 0.0013
Giardia lamblia Kinase, CAMK CAMKL 0.008 0.0398 0.165
Entamoeba histolytica hypothetical protein 0.0129 0.0851 0.3227
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0057 0.0185 0.0211
Loa Loa (eye worm) AGC/PKA protein kinase 0.0075 0.0345 0.0596
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0086 0.0449 0.1867
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0056 0.0169 0.0361
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0266 0.2125 0.2125
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0667 0.1468
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.017 0.1234 0.2139
Brugia malayi P38 map kinase family protein 2 0.017 0.1231 0.2125
Brugia malayi diacylglycerol kinase 0.0041 0.0036 0.005
Onchocerca volvulus 0.0056 0.0169 0.0505
Schistosoma mansoni tyrosine kinase 0.023 0.1786 0.396
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0084 0.0432 0.0748
Echinococcus granulosus protein tyrosine kinase 0.0038 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0126 0.0827 0.1825
Schistosoma mansoni unc-13 (munc13) 0.0043 0.0049 0.0093
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0245 0.1934 0.3347
Loa Loa (eye worm) latrophilin receptor protein 2 0.0059 0.0198 0.0342
Brugia malayi Protein kinase domain containing protein 0.0216 0.1659 0.2869
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0196 0.0722
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0059 0.0198 0.0332
Echinococcus granulosus casein kinase I alpha 0.0114 0.0712 0.0712
Entamoeba histolytica casein kinase, putative 0.0114 0.0712 0.2694
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0133 0.089 0.3732
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0038 0.0007 0.0008
Echinococcus multilocularis serine:threonine protein kinase N2 0.0143 0.0984 0.1123
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0345
Leishmania major protein kinase, putative 0.004 0.0025 0.0077
Brugia malayi ephrin receptor 1 precursor 0.0072 0.0317 0.0539
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Echinococcus multilocularis SH2 motif 0.006 0.0208 0.0238
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0208 0.0238
Loa Loa (eye worm) TK/FAK protein kinase 0.0038 0.0007 0.001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0186 0.1382 0.2387
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1091 0.189
Toxoplasma gondii AGC kinase 0.031 0.2532 1
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0019 0.0106
Schistosoma mansoni ephrin receptor 0.0109 0.0665 0.1466
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0167 0.1205 0.5062
Loa Loa (eye worm) hypothetical protein 0.0284 0.2297 0.3983
Loa Loa (eye worm) hypothetical protein 0.0136 0.0917 0.1589
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0038 0.0007 0.001
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.005 0.0116 0.046
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Trypanosoma brucei protein kinase, putative 0.0069 0.029 0.1081
Schistosoma mansoni atypical protein kinase C 0.0313 0.2561 0.5683
Leishmania major folate/biopterin transporter, putative 0.004 0.0025 0.0077
Echinococcus multilocularis dual specificity 0.0089 0.0478 0.0546
Echinococcus multilocularis twitchin 0.005 0.0111 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0384 0.3221 0.5585
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0709 0.2683
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Brugia malayi Protein kinase domain containing protein 0.0086 0.0449 0.0768
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0051 0.0123 0.0211
Loa Loa (eye worm) hypothetical protein 0.005 0.0115 0.0197
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Brugia malayi Tensin 0.006 0.0208 0.035
Leishmania major hypothetical protein, conserved 0.0126 0.082 0.3434
Brugia malayi Protein kinase domain containing protein 0.0098 0.0565 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.004 0.0025 0.0077
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0155 0.1091 0.1245
Echinococcus multilocularis unc 13 (munc13) 0.0043 0.0049 0.0055
Schistosoma mansoni tyrosine kinase 0.0088 0.047 0.1031
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.023 0.1786 0.1786
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0067 0.0278 0.0278
Trichomonas vaginalis STE family protein kinase 0.0089 0.0479 0.1804
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0646 0.1422
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0332 0.2736 0.2736
Trypanosoma cruzi casein kinase, putative 0.0114 0.0712 0.2978
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0345 0.0752
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0126 0.082 0.1412
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0056 0.0169 0.0686
Schistosoma mansoni tensin-related 0.006 0.0208 0.0448
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0384 0.3221 0.3676
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2307 0.2307
Leishmania major protein kinase, putative 0.0114 0.0709 0.2966
Toxoplasma gondii AGC kinase 0.0075 0.0345 0.1339
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0709 0.1562
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0114 0.0709 0.5859
Giardia lamblia Kinase, CMGC CLK 0.0164 0.1174 0.4932
Leishmania major protein kinase, putative 0.005 0.0116 0.046
Plasmodium vivax serine/threonine protein kinase, putative 0.0086 0.0449 0.3689
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0078 0.0375 0.0648
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0994 0.3774
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Schistosoma mansoni protein kinase C mu 0.0041 0.0036 0.0064
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0054 0.0156 0.0269
Brugia malayi Protein kinase domain containing protein 0.0657 0.5766 1
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0517 0.1136
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.1084 0.2397
Echinococcus granulosus expressed protein 0.0086 0.0449 0.0449
Entamoeba histolytica PH domain containing protein kinase, putative 0.0085 0.0437 0.1643
Echinococcus multilocularis myotubularin protein 13 0.0051 0.0128 0.0146
Schistosoma mansoni nephrin 0.0095 0.0532 0.1168
Echinococcus granulosus expressed conserved protein 0.006 0.0208 0.0208
Leishmania major serine/threonine-protein kinase, putative 0.005 0.0116 0.046
Echinococcus granulosus retinal guanylyl cyclase 2 0.0038 0.0007 0.0007
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0125 0.0215
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0089 0.0478 0.1867
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.006 0.0208 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0392 0.0858
Plasmodium falciparum protein serine/threonine kinase-1 0.0164 0.1174 0.9744
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0517 0.1951
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0007 0.0008
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0114 0.0709 0.1228
Trypanosoma cruzi cdc2-related kinase 3 0.0078 0.0375 0.1553
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0165 0.1187 0.451
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0126 0.0827 0.0827
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.017 0.1231 0.517
Entamoeba histolytica protein kinase, putative 0.0075 0.0348 0.1302
Loa Loa (eye worm) hypothetical protein 0.0097 0.0548 0.0949
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0345
Echinococcus granulosus SH2 motif 0.006 0.0208 0.0208
Echinococcus multilocularis protein patched 0.0051 0.0125 0.0143
Loa Loa (eye worm) TK/ACK protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0038 0.0007 0.0008
Echinococcus granulosus kinase suppressor of Ras 1 0.0038 0.0007 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.023 0.0387
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.017 0.1231 0.2133
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0056 0.0169 0.0686
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0517 0.1951
Entamoeba histolytica protein kinase, putative 0.0086 0.0449 0.1689
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.1755 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0778 0.2946
Echinococcus multilocularis 0.0133 0.0891 0.1017
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0756 0.0863
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis tyrosine protein kinase HCK 0.0136 0.0912 0.104
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0712 0.0812
Brugia malayi probable protein kinase 0.0086 0.0452 0.0773
Toxoplasma gondii NEK kinase 0.005 0.0116 0.0431
Entamoeba histolytica protein kinase, putative 0.0155 0.1091 0.4141
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0086 0.0452 0.0452
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0286 0.2312 0.4009
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.029 0.1195
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis PAK box P21 Rho binding 0.0065 0.0256 0.0292
Schistosoma mansoni tar DNA-binding protein 0.0062 0.023 0.0496
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.004 0.0025 0.007
Schistosoma mansoni hypothetical protein 0.0058 0.0192 0.0412
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Brugia malayi Immunoglobulin I-set domain containing protein 0.0423 0.3584 0.6211
Echinococcus multilocularis roundabout 2 0.0103 0.061 0.0696
Schistosoma mansoni tensin 0.006 0.0208 0.0448
Schistosoma mansoni tar DNA-binding protein 0.0062 0.023 0.0496
Echinococcus multilocularis RNA directed DNA polymerase 0.0044 0.0058 0.0066
Echinococcus multilocularis tyrosine protein kinase shark 0.0334 0.2761 0.3151
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0154 0.1084 0.1084
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1091 0.189
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.126 0.2788
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1805 0.4003
Echinococcus multilocularis tyrosine protein kinase Abl 0.0132 0.0881 0.1006
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0044 0.0062 0.0062
Schistosoma mansoni tensin-related 0.006 0.0208 0.0448
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0208 0.0238
Entamoeba histolytica hypothetical protein 0.0072 0.0318 0.1189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1805 0.4003
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0059 0.0198 0.0226
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0075 0.0345 0.2821
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0056 0.0169 0.0193
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Entamoeba histolytica protein kinase, putative 0.0038 0.0007 0.000000041062
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.005 0.0116 0.0416
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0089 0.0479 0.0479
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0214 0.1643 0.1643
Plasmodium falciparum calcium-dependent protein kinase 7 0.004 0.0025 0.0152
Loa Loa (eye worm) hypothetical protein 0.0044 0.0058 0.0099
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0136 0.0918 0.159
Brugia malayi Protein kinase domain containing protein 0.0078 0.0375 0.0639
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0053 0.0143 0.0522
Leishmania major protein kinase, putative 0.0088 0.0465 0.1935
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Loa Loa (eye worm) hypothetical protein 0.0657 0.5766 1
Giardia lamblia Kinase, CK1 Casein kinase 0.0114 0.0712 0.2978
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0673 0.2546
Loa Loa (eye worm) hypothetical protein 0.0059 0.0196 0.0338
Echinococcus multilocularis integrin linked protein kinase 0.0038 0.0007 0.0008
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0173 0.126 0.1438
Brugia malayi Protein kinase domain containing protein 0.009 0.0491 0.0841
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0384 0.3221 0.3221
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0286 0.2312 0.2639
Echinococcus multilocularis tyrosine protein kinase Fyn 0.023 0.1786 0.2038
Echinococcus granulosus MAP kinase activated protein kinase 2 0.043 0.3649 0.3649
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0129 0.0851 0.1475
Entamoeba histolytica protein kinase, putative 0.032 0.2624 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.023 0.1786 0.2038
Schistosoma mansoni protein kinase 0.0089 0.0479 0.105
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.2374 1
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0038 0.0007 0.001
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0039 0.001 0.0012
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0078 0.0375 0.1456
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.1174 0.4462
Plasmodium vivax serine/threonine kinase-1, putative 0.0164 0.1174 0.9744
Echinococcus multilocularis growth factor receptor bound protein 2 0.0094 0.0525 0.0599
Loa Loa (eye worm) hypothetical protein 0.0097 0.0548 0.0949
Brugia malayi Protein kinase domain containing protein 0.0072 0.0319 0.0541
Trypanosoma cruzi SNF1-related protein kinases, putative 0.008 0.0398 0.165
Giardia lamblia Kinase, AGC PKA 0.0075 0.0345 0.1428
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0293 0.2374 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0169 0.0292
Brugia malayi Tyrosine-protein kinase abl-1 0.0132 0.0881 0.1518
Echinococcus multilocularis SHC transforming protein 3 0.006 0.0208 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0069 0.0137
Echinococcus granulosus tyrosine protein kinase Src42A 0.023 0.1786 0.1786
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0084 0.0429 0.1782
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0164 0.1174 0.4932
Brugia malayi hypothetical protein 0.0214 0.1643 0.2841
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0075 0.035 0.0606
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0278 0.2236 0.3877
Schistosoma mansoni tyrosine kinase 0.0395 0.333 0.7394
Echinococcus granulosus Glutaredoxin protein 5 0.0137 0.0922 0.0922
Schistosoma mansoni hypothetical protein 0.006 0.0208 0.0448
Brugia malayi Variant SH3 domain containing protein 0.0071 0.0313 0.0532
Echinococcus multilocularis CDC7 cell division cycle 7 0.0093 0.0517 0.059
Entamoeba histolytica protein kinase, putative 0.0075 0.0348 0.1302
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0075 0.0345 0.1428
Loa Loa (eye worm) hypothetical protein 0.0076 0.0354 0.0611
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0216 0.1659 0.1893
Onchocerca volvulus Netrin receptor homolog 0.0051 0.0126 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.2125 0.4714
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Brugia malayi Bromodomain containing protein 0.0079 0.0385 0.0657
Schistosoma mansoni hypothetical protein 0.0059 0.0198 0.0425
Echinococcus multilocularis nervana 2 0.0137 0.0922 0.1052
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0089 0.0479 0.0546
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0075 0.0345 0.1339
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Schistosoma mansoni hypothetical protein 0.0059 0.0198 0.0425
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0284 0.2297 0.2297
Trichomonas vaginalis CAMK family protein kinase 0.02 0.1512 0.575
Echinococcus multilocularis serine threonine protein kinase 0.0218 0.1681 0.1918
Leishmania major protein kinase, putative 0.004 0.0025 0.0077
Plasmodium falciparum NIMA related kinase 1 0.0144 0.0994 0.8242
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0155 0.1091 0.4141
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0114 0.0709 0.2683
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0154 0.1084 0.1237
Trypanosoma brucei NIMA-related protein kinase 0.005 0.0116 0.0416
Brugia malayi hypothetical protein 0.006 0.0208 0.035
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0054 0.0156 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0116 0.0416
Loa Loa (eye worm) hypothetical protein 0.0133 0.0891 0.1544
Trichomonas vaginalis STE family protein kinase 0.0089 0.0479 0.1804
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0036 0.0064
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0057 0.0185 0.0185
Loa Loa (eye worm) RGC/RGC protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0394
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0167 0.1205 0.1375
Loa Loa (eye worm) hypothetical protein 0.0326 0.2687 0.466
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0354 0.0602
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0038 0.0007 0.0008
Loa Loa (eye worm) TK/ABL protein kinase 0.0098 0.0565 0.0978
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0094 0.0525 0.1152
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2307 0.2633
Giardia lamblia Kinase, AGC PKA 0.0167 0.1205 0.5062
Loa Loa (eye worm) hypothetical protein 0.0079 0.0384 0.0664
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Giardia lamblia Kinase, NEK 0.0144 0.0994 0.4172
Loa Loa (eye worm) loechrig isoform VII 0.0259 0.2059 0.3569
Toxoplasma gondii NEK kinase 0.005 0.0116 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0125 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.026 0.2066 0.4583
Entamoeba histolytica serine/threonine protein kinase, putative 0.008 0.0398 0.1493
Trichomonas vaginalis AGC family protein kinase 0.0196 0.147 0.5591
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0657 0.5766 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0101 0.0594 0.0678
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0455 0.1714
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0394
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0086 0.0452 0.0516
Echinococcus granulosus casein kinase I delta 0.0114 0.0712 0.0712
Schistosoma mansoni tyrosine kinase 0.0073 0.033 0.0718
Onchocerca volvulus 0.0158 0.1119 0.3461
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis transfer RNA-Thr 0.0038 0.0007 0.0008
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0164 0.1174 0.4462
Echinococcus multilocularis tyrosine kinase 0.0098 0.0565 0.0645
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis myosin iiia 0.0088 0.0465 0.0531
Echinococcus multilocularis tyrosine protein kinase Fyn 0.023 0.1786 0.2038
Echinococcus granulosus tyrosine protein kinase Src64B 0.023 0.1786 0.1786
Schistosoma mansoni ste20-related kinase 0.0221 0.1704 0.3777
Trypanosoma brucei aurora B kinase 0.0155 0.1091 0.4141
Loa Loa (eye worm) hypothetical protein 0.0153 0.1078 0.1867
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0196 0.147 0.1677
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0175 0.1282 0.2222
Echinococcus granulosus activated cdc42 kinase 1 0.0038 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0038 0.0007 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Loa Loa (eye worm) RNA binding protein 0.0062 0.023 0.0396
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Trypanosoma brucei protein kinase, putative 0.0136 0.0918 0.348
Loa Loa (eye worm) hypothetical protein 0.0186 0.1382 0.2395
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0088 0.0465 0.175
Trichomonas vaginalis STE family protein kinase 0.0089 0.0479 0.1804
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0075 0.0345 0.1292
Schistosoma mansoni vesicular amine transporter 0.0069 0.0292 0.0634
Echinococcus granulosus myotubularin protein 13 0.0051 0.0128 0.0128
Echinococcus granulosus tyrosine protein kinase shark 0.0334 0.2761 0.2761
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.1042 0.1189
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0838 0.1849
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0236 0.1842 0.2102
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0086 0.0449 0.1689
Loa Loa (eye worm) hypothetical protein 0.0158 0.1119 0.194
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0657 0.5766 1
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0094 0.0525 0.0908
Echinococcus multilocularis dual specificity protein kinase clk2 0.0164 0.1174 0.134
Echinococcus granulosus nervana 2 0.0137 0.0922 0.0922
Loa Loa (eye worm) SRC-1 0.023 0.1786 0.3096
Entamoeba histolytica PH domain containing protein kinase, putative 0.0085 0.0437 0.1643
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Plasmodium vivax protein kinase Crk2 0.0078 0.0375 0.3069
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.043 0.3649 0.6328
Echinococcus multilocularis mitogen activated protein kinase 14 0.017 0.1231 0.1405
Schistosoma mansoni hypothetical protein 0.0072 0.0318 0.0693
Loa Loa (eye worm) hypothetical protein 0.007 0.03 0.0519
Echinococcus granulosus GPCR family 2 0.0059 0.0198 0.0198
Brugia malayi hypothetical protein 0.0286 0.2307 0.3995
Echinococcus granulosus cyclin dependent kinase 1 0.0078 0.0375 0.0375
Onchocerca volvulus Serine\/threonine kinase homolog 0.0293 0.2374 0.7366
Schistosoma mansoni bromodomain containing protein 0.0067 0.0278 0.0603
Echinococcus granulosus mitogen activated protein kinase 14 0.017 0.1231 0.1231
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0056 0.0169 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0205 0.1562 0.5943
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0132 0.0881 0.1946
Loa Loa (eye worm) TK/CSK protein kinase 0.0038 0.0007 0.001
Entamoeba histolytica protein kinase, putative 0.0089 0.0478 0.1802
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0089 0.0479 0.0546
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0156 0.0332
Echinococcus multilocularis rac serine:threonine kinase 0.0177 0.1297 0.148
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Brugia malayi Fes/CIP4 homology domain containing protein 0.0118 0.0747 0.1285
Echinococcus multilocularis SH2 domain containing protein 7 0.006 0.0208 0.0238
Echinococcus multilocularis serine:threonine protein kinase N2 0.0173 0.126 0.1438
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0673 0.2546
Onchocerca volvulus 0.0071 0.0309 0.0939
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0155 0.1091 0.4141
Echinococcus granulosus SHC transforming protein 3 0.006 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0084 0.0427 0.1665
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0712 0.0812
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0188 0.1402 0.2431
Onchocerca volvulus 0.0136 0.0918 0.2834
Entamoeba histolytica serine/threonine protein kinase, putative 0.005 0.0116 0.0416
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0089 0.0478 0.0819
Echinococcus granulosus tyrosine protein kinase Fyn 0.023 0.1786 0.1786
Echinococcus granulosus tyrosine kinase 0.0098 0.0565 0.0565
Brugia malayi Protein-tyrosine phosphatase containing protein 0.006 0.0208 0.035
Trypanosoma cruzi casein kinase, putative 0.0114 0.0712 0.2978
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0167 0.1205 1
Echinococcus multilocularis death associated protein kinase 1 0.0932 0.8321 0.9496
Schistosoma mansoni protein kinase 0.0155 0.1091 0.2412
Echinococcus multilocularis cyclin dependent kinase 1 0.0078 0.0375 0.0427
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0208 0.0359
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0038 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.009 0.0491 0.1078
Echinococcus granulosus twitchin 0.0119 0.0753 0.0753
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0075 0.0345 0.1428
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0056 0.0169 0.062
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0245 0.1934 0.3353
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0063 0.0235 0.0873
Echinococcus multilocularis activated cdc42 kinase 1 0.0038 0.0007 0.0008
Echinococcus multilocularis raf serine:threonine protein kinase 0.008 0.0392 0.0448
Echinococcus multilocularis insulin receptor 0.009 0.0491 0.056
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0038 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0274 0.2203 0.4888
Echinococcus granulosus roundabout 2 0.0103 0.061 0.061
Schistosoma mansoni serine/threonine protein kinase 0.043 0.3649 0.8105
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.0478 0.1802
Echinococcus multilocularis serine:threonine kinase SAD 1 0.008 0.0398 0.0454
Schistosoma mansoni rap gtpase-activating protein 0.0056 0.0169 0.0361
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0025 0.007
Trypanosoma cruzi cdc2-related kinase 1 0.0078 0.0375 0.1553
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0072 0.0323 0.0368
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0756 0.0756
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0038 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.1091 0.2412
Echinococcus multilocularis epidermal growth factor receptor 0.0203 0.1541 0.1758
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0712 0.0812
Schistosoma mansoni protein kinase 0.0065 0.0256 0.0554
Echinococcus granulosus suppressor of cytokine signaling 7 0.006 0.0208 0.0208
Trypanosoma cruzi casein kinase, putative 0.0114 0.0712 0.2978
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0116 0.0416
Loa Loa (eye worm) TK/RYK protein kinase 0.0038 0.0007 0.001
Echinococcus granulosus AMPK beta subunit 0.0126 0.082 0.082
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Echinococcus granulosus serine:threonine protein kinase 3 0.0278 0.2236 0.2236
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0087 0.0455 0.1776
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0553 0.0553
Trypanosoma brucei protein kinase, putative 0.004 0.0025 0.007
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0384 0.3221 0.5585
Trichomonas vaginalis set domain proteins, putative 0.0219 0.1692 0.6438
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0089 0.0478 0.1992
Loa Loa (eye worm) casein kinase 0.0199 0.1505 0.2608
Echinococcus granulosus integrin linked protein kinase 0.0038 0.0007 0.0007
Echinococcus granulosus ephrin type A receptor 4 A 0.0109 0.0665 0.0665
Schistosoma mansoni protein kinase C 0.0043 0.0049 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0069 0.0137
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.004 0.0025 0.0077
Loa Loa (eye worm) AGC/NDR protein kinase 0.0173 0.126 0.2183
Loa Loa (eye worm) AGC/PKA protein kinase 0.0075 0.0345 0.0596
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0043 0.0049 0.0049
Echinococcus multilocularis GPCR, family 2 0.0059 0.0198 0.0226
Brugia malayi casein kinase I 0.0114 0.0712 0.1224
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0129 0.0851 0.3568
Echinococcus granulosus tyrosine protein kinase ABL1 0.0098 0.0565 0.0565
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0394
Loa Loa (eye worm) hypothetical protein 0.0153 0.1078 0.1867
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Schistosoma mansoni protein kinase 0.0089 0.0479 0.105
Brugia malayi RNA binding protein 0.0062 0.023 0.0387
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Brugia malayi hypothetical protein 0.0098 0.0565 0.0969
Onchocerca volvulus 0.0098 0.0565 0.1736
Schistosoma mansoni unc-13 (munc13) 0.0043 0.0049 0.0093
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.008 0.0398 0.165
Loa Loa (eye worm) hypothetical protein 0.0395 0.3329 0.5773
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus granulosus signal transduction protein lnk realted 0.006 0.0208 0.0208
Echinococcus granulosus mitogen activated protein kinase 0.0087 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0019 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0345 0.1292
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0155 0.1091 0.4141
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0136 0.0918 0.159
Onchocerca volvulus 0.006 0.0208 0.0626
Brugia malayi Sex muscle abnormal protein 5 0.0094 0.0525 0.0899
Echinococcus multilocularis 0.006 0.0208 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0894 0.339
Leishmania major protein kinase, putative 0.0155 0.1091 0.4578
Echinococcus granulosus aurora kinase A 0.0155 0.1091 0.1091
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0038 0.0007 0.0008
Echinococcus multilocularis expressed conserved protein 0.0112 0.0689 0.0787
Loa Loa (eye worm) hypothetical protein 0.0069 0.0292 0.0504
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.2312 0.5131
Schistosoma mansoni titin 0.0056 0.0173 0.037
Echinococcus multilocularis dual specificity 0.0089 0.0478 0.0546
Echinococcus granulosus NCK adaptor protein 0.0094 0.0525 0.0525
Brugia malayi Fibronectin type III domain containing protein 0.0076 0.0354 0.0602
Echinococcus multilocularis SH2 motif 0.006 0.0208 0.0238
Echinococcus multilocularis casein kinase i 0.0114 0.0712 0.0812
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0398 0.0869
Brugia malayi Protein kinase domain containing protein 0.0175 0.1282 0.2214
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0136 0.0918 0.3607
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0167 0.1205 0.1205
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0359 0.2993 0.2993
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0084 0.0432 0.0748
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.017 0.1231 0.517
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.023 0.0396
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0126 0.082 0.3434
Echinococcus granulosus dual specificity 0.0089 0.0478 0.0478
Echinococcus multilocularis protein dispatched 1 0.0058 0.0192 0.0219
Schistosoma mansoni rac gtpase activating protein 0.0041 0.0036 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0449 0.0984
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0918 0.348
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0087 0.0455 0.1895
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.008 0.0398 0.165
Echinococcus multilocularis protein kinase c epsilon type 0.0216 0.1658 0.1892
Entamoeba histolytica PH domain containing protein kinase, putative 0.0177 0.1297 0.4931
Echinococcus multilocularis suppressor of cytokine signaling 6 0.006 0.0208 0.0238
Echinococcus granulosus tyrosine protein kinase Fyn 0.023 0.1786 0.1786
Onchocerca volvulus 0.006 0.0208 0.0626
Schistosoma mansoni survival motor neuron protein 0.0058 0.0192 0.0412
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0164 0.1174 0.2035
Loa Loa (eye worm) protein kinase domain-containing protein 0.0038 0.0007 0.001
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0086 0.0449 0.1751
Echinococcus multilocularis casein kinase I gamma 0.023 0.1788 0.204
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0114 0.0709 0.0709
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0075 0.0345 0.1428
Brugia malayi CHE-14 protein 0.0051 0.0125 0.0205
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0038 0.0007 0.001
Brugia malayi latrophilin 2 splice variant baaae 0.0127 0.0834 0.1436
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.1174 0.2598
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Schistosoma mansoni tyrosine kinase 0.0088 0.047 0.1031
Trichomonas vaginalis TKL family protein kinase 0.0038 0.0007 0.000000041062
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0196 0.147 0.147
Schistosoma mansoni hypothetical protein 0.0504 0.4336 0.9634
Echinococcus multilocularis serine:threonine protein kinase 0.0075 0.035 0.04
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0173 0.126 0.1438
Onchocerca volvulus 0.006 0.0208 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0455 0.1714
Onchocerca volvulus 0.0098 0.0565 0.1736
Echinococcus granulosus cyclin dependent kinase 0.0078 0.0375 0.0375
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0427 0.3625 0.3625
Brugia malayi protein kinase C3,putative 0.0163 0.1171 0.2022
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.029 0.1195
Echinococcus granulosus receptor type guanylyl cyclase 0.0038 0.0007 0.0007
Toxoplasma gondii NEK kinase 0.005 0.0116 0.0431
Loa Loa (eye worm) TK/EGFR protein kinase 0.0203 0.1541 0.2671
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0087 0.0455 0.1895
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0982 0.0982
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0038 0.0007 0.0007
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0259 0.2059 0.2059
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0114 0.0709 0.0709
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0144 0.0994 0.3911
Echinococcus multilocularis aurora kinase A 0.0155 0.1091 0.1245
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0712 0.1233
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0101 0.0594 0.1306
Schistosoma mansoni tensin 0.006 0.0208 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0667 0.1468
Echinococcus granulosus Diacylglycerol kinase theta 0.0041 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.0089 0.0479 0.1804
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Onchocerca volvulus 0.0084 0.0429 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1091 0.4141
Brugia malayi hypothetical protein 0.0056 0.0169 0.0282
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0007 0.0008
Toxoplasma gondii protein kinase domain-containing protein 0.004 0.0025 0.0072
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.1231 0.1231
Onchocerca volvulus 0.0098 0.0565 0.1736
Giardia lamblia Kinase, NEK 0.0038 0.0007 0.000000045391
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0712 0.2694
Entamoeba histolytica protein kinase, putative 0.004 0.0025 0.007
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0208 0.0359
Echinococcus multilocularis c src tyrosine kinase 0.0132 0.0881 0.1006
Schistosoma mansoni protein kinase 0.0359 0.2993 0.6646
Entamoeba histolytica serine/threonine protein kinase, putative 0.0293 0.2374 0.9046
Loa Loa (eye worm) TK protein kinase 0.0423 0.3584 0.6215
Echinococcus granulosus titin 0.0056 0.0173 0.0173
Onchocerca volvulus 0.0039 0.0009 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0059 0.0198 0.0198
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0208 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0667 0.1468
Echinococcus granulosus tensin C1 domain containing phosphatase 0.006 0.0208 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Onchocerca volvulus 0.0093 0.0517 0.1589
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Echinococcus multilocularis serine:threonine protein kinase 38 0.0173 0.126 0.1438
Leishmania major casein kinase, putative 0.0114 0.0712 0.2978
Entamoeba histolytica hypothetical protein 0.0039 0.001 0.0012
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0044 0.0062 0.0071
Echinococcus multilocularis protein KINase family member (kin 25) 0.0038 0.0007 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0116 0.0242
Echinococcus multilocularis dual specificity 0.0089 0.0478 0.0546
Brugia malayi diacylglycerol kinase 0.0041 0.0036 0.005
Brugia malayi Stress-activated protein kinase jnk-1 0.0286 0.2312 0.4003
Entamoeba histolytica protein kinase 2, putative 0.0167 0.1205 0.4579
Entamoeba histolytica protein kinase, putative 0.0129 0.0851 0.3227
Echinococcus granulosus serine:threonine protein kinase 0.0075 0.035 0.035
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1091 0.4141
Echinococcus multilocularis expressed protein 0.0086 0.0449 0.0512
Brugia malayi Protein kinase domain containing protein 0.0098 0.0565 0.0969
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0039 0.0009 0.001
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0101 0.0594 0.1306
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0154 0.1084 0.1084
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0054 0.0156 0.0259
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0075 0.0075
Echinococcus multilocularis protein kinase c eta type 0.0041 0.0036 0.0041
Echinococcus granulosus calcium dependent protein kinase 0.0083 0.0426 0.0426
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0186 0.1382 0.2395
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.1231 0.1405
Schistosoma mansoni vam6/vps39 related 0.0056 0.0169 0.0361
Plasmodium falciparum serine/threonine protein kinase, putative 0.0155 0.1091 0.9044
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0136 0.0918 0.3847
Brugia malayi RhoGAP domain containing protein 0.0101 0.0594 0.1019
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0069 0.0292 0.0634
Schistosoma mansoni growth factor receptor-bound protein 0.0094 0.0525 0.1152
Echinococcus granulosus suppressor of cytokine signaling 6 0.006 0.0208 0.0208
Echinococcus granulosus titin 0.0056 0.0173 0.0173
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0128 0.0838 0.0838
Echinococcus multilocularis heat shock protein 70 0.0038 0.0007 0.0008
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Brugia malayi TAR-binding protein 0.0062 0.023 0.0387
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0019 0.0053
Echinococcus multilocularis tensin 0.006 0.0208 0.0238
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0038 0.0007 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0727 0.125
Leishmania major protein kinase, putative 0.0164 0.1174 0.4932
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0116 0.0416
Brugia malayi Latrophilin receptor protein 2 0.0059 0.0198 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus granulosus insulin receptor 0.009 0.0491 0.0491
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0164 0.1174 0.4624
Schistosoma mansoni protein kinase 0.0069 0.029 0.063
Trichomonas vaginalis TKL family protein kinase 0.0038 0.0007 0.000000041062
Brugia malayi SRC-1 0.023 0.1786 0.3089
Loa Loa (eye worm) hypothetical protein 0.0051 0.0128 0.0219
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0075 0.0566
Echinococcus granulosus raf serine:threonine protein kinase 0.008 0.0392 0.0392
Giardia lamblia Kinase, NEK 0.005 0.0116 0.046
Onchocerca volvulus 0.0219 0.1692 0.5242
Loa Loa (eye worm) raf kinase 0.0041 0.0036 0.006
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0159 0.1133 0.1294
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.126 0.2788
Brugia malayi Variant SH3 domain containing protein 0.0101 0.0594 0.1019
Trichomonas vaginalis STE family protein kinase 0.0089 0.0479 0.1804
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0089 0.0478 0.0828
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0086 0.0449 0.1867
Schistosoma mansoni hypothetical protein 0.006 0.0208 0.0448
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0114 0.0712 0.1233
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.006 0.0208 0.0359
Schistosoma mansoni signal transduction protein lnk-related 0.006 0.0208 0.0448
Schistosoma mansoni tyrosine kinase 0.0088 0.047 0.1031
Echinococcus granulosus netrin receptor unc 5 0.004 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0056 0.0169 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0196 0.147 0.5591
Echinococcus multilocularis protein kinase 0.0038 0.0007 0.0008
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0041 0.0027 0.0031
Schistosoma mansoni serine/threonine-protein kinase 0.0177 0.1297 0.2871
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0114 0.0709 0.2781
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.043 0.3649 0.4164
Schistosoma mansoni cell adhesion molecule 0.0084 0.0432 0.0946
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0069 0.0292 0.0634
Loa Loa (eye worm) CAMK/PKD protein kinase 0.023 0.1788 0.3099
Schistosoma mansoni growth factor receptor-bound protein 0.0096 0.0545 0.1198
Echinococcus multilocularis signal transduction protein lnk realted 0.006 0.0208 0.0238
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0098 0.0565 0.2132
Trichomonas vaginalis STE family protein kinase 0.0065 0.0256 0.0951
Echinococcus granulosus Protein kinase C brain isozyme 0.026 0.2066 0.2066
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.005 0.0116 0.046
Echinococcus multilocularis tar DNA binding protein 0.0062 0.023 0.0262
Echinococcus granulosus mitogen activated protein kinase 11 0.017 0.1231 0.1231
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Echinococcus multilocularis casein kinase I delta 0.0114 0.0712 0.0812
Trichomonas vaginalis AGC family protein kinase 0.004 0.0025 0.007
Trypanosoma brucei rac serine-threonine kinase, putative 0.032 0.2624 1
Brugia malayi Ras association domain family 1 isoform A 0.0041 0.0036 0.005
Entamoeba histolytica casein kinase 1, putative 0.0114 0.0712 0.2694
Entamoeba histolytica hypothetical protein 0.004 0.0025 0.007
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0164 0.1174 0.4462
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0125 0.0125
Loa Loa (eye worm) CDC7 protein kinase 0.0093 0.0517 0.0896
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0214 0.1643 0.2848
Plasmodium falciparum protein kinase, putative 0.0069 0.029 0.2362
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0136 0.0918 0.1047
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.023 0.1786 0.2038
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.031 0.2532 0.439
Echinococcus multilocularis calcium dependent protein kinase 0.0083 0.0426 0.0486
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.005 0.0116 0.046
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0094 0.0525 0.0908
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0114 0.0709 0.0809
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Schistosoma mansoni tyrosine kinase 0.023 0.1786 0.396
Entamoeba histolytica hypothetical protein 0.004 0.0025 0.007
Onchocerca volvulus Alicorn homolog 0.011 0.0672 0.2069
Onchocerca volvulus 0.0114 0.0712 0.2193
Entamoeba histolytica protein kinase , putative 0.0155 0.1091 0.4141
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0063 0.0235 0.0873
Entamoeba histolytica hypothetical protein 0.0072 0.0318 0.1189
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0851 0.3227
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Echinococcus granulosus dual specificity 0.0129 0.0851 0.0851
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0227 0.087
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0293 0.2374 0.4117
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0114 0.0709 0.5859
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.006 0.0208 0.0626
Entamoeba histolytica protein kinase, putative 0.0086 0.0449 0.1689
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0075 0.0269
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0094 0.0525 0.0908
Loa Loa (eye worm) TK/ALK protein kinase 0.0308 0.2515 0.436
Loa Loa (eye worm) TK/ROR protein kinase 0.0057 0.0185 0.0319
Loa Loa (eye worm) AGC/AKT protein kinase 0.032 0.2624 0.4549
Brugia malayi Doublecortin family protein 0.0161 0.1145 0.1977
Schistosoma mansoni nck2/grb4 0.0094 0.0525 0.1152
Schistosoma mansoni hypothetical protein 0.0166 0.1194 0.2642
Schistosoma mansoni hypothetical protein 0.0049 0.0108 0.0225
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0193 0.1445 0.2504
Giardia lamblia Kinase, STE STE20 0.0089 0.0479 0.1994
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0038 0.0007 0.0008
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0114 0.0712 0.2978
Loa Loa (eye worm) hypothetical protein 0.004 0.0022 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.026 0.2066 0.4583
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0086 0.0449 0.0777
Entamoeba histolytica protein kinase, putative 0.0039 0.001 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0076 0.0354 0.0612
Brugia malayi hypothetical protein 0.0072 0.0318 0.054
Brugia malayi Pleckstrin Homology Domain 0.0051 0.0128 0.021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1805 0.206
Trichomonas vaginalis STE family protein kinase 0.005 0.0116 0.0416
Brugia malayi casein kinase 1, delta 0.0114 0.0712 0.1224
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.004 0.0025 0.007
Onchocerca volvulus 0.0209 0.1597 0.4947
Brugia malayi RhoGEF domain containing protein 0.0041 0.0036 0.005
Leishmania major serine/threonine-protein kinase a, putative 0.004 0.0025 0.0077
Trypanosoma cruzi NIMA-related kinase, putative 0.004 0.0025 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0345 0.0752
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.004 0.0025 0.0077
Brugia malayi Protein kinase domain containing protein 0.0384 0.3221 0.5581
Echinococcus multilocularis mitogen activated protein kinase 11 0.017 0.1231 0.1405
Onchocerca volvulus 0.0064 0.0249 0.0755
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0114 0.0709 0.2781
Plasmodium falciparum NIMA related kinase 2 0.005 0.0116 0.0909
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.45 1
Schistosoma mansoni tyrosine kinase 0.0132 0.0881 0.1946
Echinococcus granulosus tyrosine protein kinase 0.0038 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0136 0.0912 0.3457
Entamoeba histolytica diacylglycerol kinase, putative 0.0041 0.0036 0.011
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Echinococcus granulosus protein kinase c iota type 0.0306 0.2498 0.2498
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0053 0.0143 0.0522
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0359 0.2993 0.3416
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.023 0.1786 0.1786
Entamoeba histolytica protein kinase, putative 0.032 0.2624 1
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0293 0.2381 0.2381
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0214 0.1643 0.1875
Entamoeba histolytica cell division protein kinase 2, putative 0.0078 0.0375 0.1405
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0075 0.0345 0.1292
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Echinococcus multilocularis hypothetical protein 0.0079 0.0384 0.0438
Echinococcus multilocularis tyrosine protein kinase Fgr 0.023 0.1786 0.2038
Schistosoma mansoni protein kinase 0.0038 0.0007 0.000000023914
Schistosoma mansoni shc transforming protein 0.006 0.0208 0.0448
Brugia malayi Protein kinase domain 0.0089 0.0479 0.082
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0007 0.0007
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis titin 0.0056 0.0173 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Leishmania major protein kinase A catalytic subunit isoform 1 0.0075 0.0345 0.1428
Schistosoma mansoni kinase 0.0313 0.2564 0.5691
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0101 0.0594 0.0594
Echinococcus multilocularis protein kinase c iota type 0.0306 0.2498 0.2851
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Trichomonas vaginalis AGC family protein kinase 0.004 0.0025 0.007
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0078 0.0375 0.0648
Echinococcus granulosus nervana 2 0.0137 0.0922 0.0922
Echinococcus granulosus SH2 domain containing protein 7 0.006 0.0208 0.0208
Echinococcus multilocularis receptor type guanylyl cyclase 0.0038 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0056 0.0096
Trypanosoma brucei casein kinase I, isoform 2 0.0114 0.0712 0.2694
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0251 0.1981 0.3435
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0918 0.348
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.004 0.0025 0.0152
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0036 0.0064
Entamoeba histolytica PH domain containing protein kinase, putative 0.004 0.0025 0.007
Trichomonas vaginalis STE family protein kinase 0.0144 0.0994 0.3774
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0778 0.2946
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0136 0.0917 0.1589
Entamoeba histolytica protein kinase, putative 0.0072 0.0323 0.1207
Schistosoma mansoni hypothetical protein 0.0049 0.0108 0.0225
Brugia malayi tRNA modification GTPase TrmE family protein 0.006 0.0208 0.035
Loa Loa (eye worm) hypothetical protein 0.0098 0.0565 0.0978
Brugia malayi Protein kinase domain containing protein 0.0308 0.2516 0.4356
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0332 0.2736 0.3123
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0041 0.0036 0.006
Brugia malayi Protein kinase domain containing protein 0.0164 0.1174 0.2027
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Brugia malayi Serine/threonine-protein kinase SULU 0.0214 0.1643 0.2841
Loa Loa (eye worm) hypothetical protein 0.0056 0.0169 0.0292
Echinococcus granulosus tensin 0.006 0.0208 0.0208
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0126 0.082 0.3107
Brugia malayi Protein kinase domain containing protein 0.0062 0.023 0.0388
Leishmania major protein kinase, putative 0.0164 0.1174 0.4932
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0404 0.3406 0.3887
Echinococcus multilocularis tyrosine protein kinase Src64B 0.023 0.1786 0.2038
Echinococcus multilocularis cyclin dependent kinase 1 0.0078 0.0375 0.0427
Loa Loa (eye worm) hypothetical protein 0.0069 0.0292 0.0504
Echinococcus granulosus protein kinase 0.0038 0.0007 0.0007
Entamoeba histolytica SH2-protein kinase domain containing protein 0.009 0.0491 0.1851
Leishmania major protein kinase, putative 0.0069 0.029 0.1195
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Echinococcus granulosus SH2 motif 0.006 0.0208 0.0208
Plasmodium falciparum casein kinase 1 0.0114 0.0712 0.5882
Schistosoma mansoni serine/threonine-protein kinase 0.0177 0.1297 0.2871
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.005 0.0116 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0196 0.147 0.2548
Brugia malayi Kinase associated domain 1 family protein 0.0079 0.0384 0.0654
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0041 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0084 0.0432 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.1084 0.2397
Schistosoma mansoni serine/threonine kinase 0.02 0.1512 0.3349
Loa Loa (eye worm) hypothetical protein 0.0059 0.0198 0.0342
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0067 0.0278 0.0317
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.017 0.1231 0.517
Loa Loa (eye worm) hypothetical protein 0.0209 0.1597 0.2768
Onchocerca volvulus 0.006 0.0208 0.0626
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0208 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Schistosoma mansoni SH2A 0.006 0.0208 0.0448
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Echinococcus granulosus activin receptor type 0.0069 0.029 0.029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0455 0.1895
Echinococcus granulosus tyrosine kinase 0.0038 0.0007 0.0007
Schistosoma mansoni protein kinase 0.0332 0.2736 0.6074
Brugia malayi Protein kinase domain containing protein 0.0098 0.0565 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.2381 0.5283
Entamoeba histolytica protein kinase, putative 0.0065 0.0256 0.0951
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0216 0.1659 0.2876
Echinococcus granulosus hypothetical protein 0.006 0.0208 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0038 0.0007 0.000000041062
Plasmodium vivax protein kinase, putative 0.0055 0.0162 0.1295
Brugia malayi Bromodomain containing protein 0.0041 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0119 0.0756 0.131
Toxoplasma gondii aurora kinase 0.0155 0.1091 0.4292
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Echinococcus granulosus defective proboscis extension response 0.0069 0.0292 0.0292
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0192 0.0322
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0208 0.0448
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0069 0.029 0.029
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0054 0.0156 0.0269
Loa Loa (eye worm) hypothetical protein 0.0075 0.0345 0.0596
Plasmodium falciparum glycogen synthase kinase 3 0.0136 0.0918 0.76
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0216 0.1658 0.2875
Brugia malayi Temporarily assigned gene name protein 59 0.0056 0.0169 0.0282
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0087 0.0455 0.1895
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.023 0.1786 0.2038
Echinococcus multilocularis mitogen activated protein kinase 14 0.017 0.1231 0.1405
Entamoeba histolytica PH domain containing protein kinase, putative 0.0177 0.1297 0.4931
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0114 0.0709 0.5859
Echinococcus multilocularis protein kinase 0.0038 0.0007 0.0008
Echinococcus multilocularis activin receptor type 0.0069 0.029 0.0331
Plasmodium vivax calcium-dependent protein kinase, putative 0.0114 0.0709 0.5859
Brugia malayi serine/threonine kinase 12 0.0155 0.1091 0.1882
Schistosoma mansoni protein kinase 0.0069 0.029 0.063
Brugia malayi intracellular kinase 0.0136 0.0918 0.1581
Echinococcus multilocularis tyrosine kinase 0.0038 0.0007 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0216 0.1659 0.1659
Giardia lamblia Kinase, CMGC GSK 0.0136 0.0918 0.3847
Loa Loa (eye worm) TK protein kinase 0.0136 0.0912 0.1579
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.2593 0.5756
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0293 0.2381 0.2717
Giardia lamblia Kinase, NEK 0.0144 0.0994 0.4172
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0161 0.1145 0.1985
Echinococcus multilocularis Protein kinase C, brain isozyme 0.026 0.2066 0.2358
Loa Loa (eye worm) TK protein kinase 0.0374 0.3128 0.5424
Entamoeba histolytica protein kinase, putative 0.0038 0.0007 0.000000041062
Echinococcus granulosus protein kinase c epsilon type 0.0216 0.1658 0.1658
Schistosoma mansoni tensin 0.006 0.0208 0.0448
Schistosoma mansoni protein kinase 0.0114 0.0712 0.1569
Entamoeba histolytica hypothetical protein 0.0039 0.001 0.0012
Echinococcus multilocularis kinase suppressor of Ras 1 0.0038 0.0007 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1659 0.3677
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0323 0.0368
Schistosoma mansoni hypothetical protein 0.0049 0.0108 0.0225
Trypanosoma brucei cdc2-related kinase 1 0.0078 0.0375 0.1405
Plasmodium falciparum calcium-dependent protein kinase 3 0.0114 0.0709 0.5859
Echinococcus granulosus tar DNA binding protein 0.0062 0.023 0.023
Loa Loa (eye worm) TK/Met protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis 0.0051 0.0128 0.0146
Schistosoma mansoni protein kinase 0.0086 0.0452 0.0991
Toxoplasma gondii histone kinase SNF1, putative 0.008 0.0398 0.1547
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0284 0.2297 0.5097
Entamoeba histolytica hypothetical protein 0.0044 0.0058 0.0197
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Entamoeba histolytica protein kinase, putative 0.004 0.0025 0.007
Loa Loa (eye worm) hypothetical protein 0.0069 0.0295 0.0509
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0069 0.0292 0.0333
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.006 0.0208 0.0626
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0007 0.0008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0245 0.0245
Echinococcus granulosus serine:threonine protein kinase N2 0.0143 0.0984 0.0984
Loa Loa (eye worm) protein-tyrosine phosphatase 0.006 0.0208 0.0359
Echinococcus multilocularis tyrosine protein kinase Src42A 0.023 0.1786 0.2038
Schistosoma mansoni GTPase activating protein 0.006 0.0208 0.0448
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.004 0.0025 0.0077
Loa Loa (eye worm) RGC/RGC protein kinase 0.0038 0.0007 0.001
Onchocerca volvulus 0.006 0.0208 0.0626
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.049 0.4208 0.7298
Entamoeba histolytica protein kinase, putative 0.031 0.2532 0.9649
Giardia lamblia Kinase, CMGC SRPK 0.0086 0.0449 0.1867
Onchocerca volvulus 0.0153 0.1078 0.3332
Plasmodium vivax glycogen synthase kinase 3, putative 0.0136 0.0918 0.76
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0088 0.0465 0.175
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0137 0.0922 0.1052
Echinococcus granulosus geminin 0.0166 0.1194 0.1194
Brugia malayi hypothetical protein 0.0136 0.0917 0.1581
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0208 0.0238
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0089 0.0479 0.0479
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Entamoeba histolytica cell division protein kinase 2, putative 0.0078 0.0375 0.1405
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0398 0.0869
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0323 0.0323
Entamoeba histolytica hypothetical protein 0.0039 0.001 0.0012
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0089 0.0478 0.1802
Trypanosoma brucei protein kinase, putative 0.0087 0.0455 0.1714
Giardia lamblia Kinase, NEK 0.0144 0.0994 0.4172
Loa Loa (eye worm) hypothetical protein 0.0099 0.0568 0.0984
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0156 0.0332
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0208 0.0238
Trypanosoma brucei polo-like protein kinase 0.0293 0.2374 0.9046
Giardia lamblia Kinase, CMGC CDK 0.0078 0.0375 0.1553
Trypanosoma cruzi serine/threonine protein kinase, putative 0.004 0.0025 0.0077
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0114 0.0709 0.1228
Giardia lamblia Kinase, CMGC MAPK 0.0087 0.0455 0.1895
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0074 0.034 0.132
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.1643 0.3641
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0918 0.348
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0084 0.0432 0.0493
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0434 0.3686 0.3686
Brugia malayi STE20-like kinase MST 0.0278 0.2236 0.3871
Echinococcus granulosus epidermal growth factor receptor 0.0203 0.1541 0.1541
Toxoplasma gondii diacylglycerol kinase, putative 0.0041 0.0036 0.0114
Schistosoma mansoni protein kinase 0.0069 0.029 0.063
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0427 0.3625 0.4137
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0851 0.188
Schistosoma mansoni hypothetical protein 0.0049 0.0108 0.0225
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0175 0.1282 0.1282
Echinococcus granulosus tyrosine protein kinase Lyn 0.026 0.2069 0.2069
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0375 0.0818
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.1174 0.2598
Onchocerca volvulus 0.0058 0.0192 0.0576
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0038 0.0007 0.0007
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0059 0.0198 0.0226
Echinococcus granulosus dual specificity protein kinase clk2 0.0164 0.1174 0.1174
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.004 0.0025 0.0077
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0044 0.0058 0.0066
Echinococcus granulosus Rac GTPase activating protein 1 0.0041 0.0036 0.0036
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0128 0.0838 0.0956
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0038 0.0007 0.0008
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0038 0.0007 0.001
Plasmodium falciparum calcium-dependent protein kinase 4 0.0114 0.0709 0.5859
Plasmodium falciparum serine/threonine protein kinase KIN 0.008 0.0398 0.326
Echinococcus granulosus c src tyrosine kinase 0.0132 0.0881 0.0881
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.1282 0.2838
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.008 0.0398 0.165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1805 0.206
Echinococcus multilocularis tyrosine protein kinase 0.0038 0.0007 0.0008
Echinococcus granulosus casein kinase I alpha 0.0114 0.0712 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.3221 0.7152
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0114 0.0709 0.0809
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0007 0.0007
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0173 0.126 0.2183
Echinococcus granulosus epidermal growth factor receptor 0.0126 0.0827 0.0827
Loa Loa (eye worm) TAR-binding protein 0.0062 0.023 0.0396
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0126 0.082 0.1412
Echinococcus granulosus neuroglian 0.0088 0.047 0.047
Schistosoma mansoni tyrosine kinase 0.0404 0.3406 0.7564
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0075 0.035 0.0606
Entamoeba histolytica diacylglycerol kinase, putative 0.0041 0.0036 0.011
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0136 0.0918 0.0918
Schistosoma mansoni tar DNA-binding protein 0.0062 0.023 0.0496
Brugia malayi Pre-SET motif family protein 0.0193 0.1445 0.2497
Echinococcus multilocularis natriuretic peptide receptor 1 0.0038 0.0007 0.0008
Loa Loa (eye worm) CAMK protein kinase 0.0056 0.0173 0.0299
Trypanosoma brucei SNF1-related protein kinases, putative 0.008 0.0398 0.1493
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0375 0.0818
Plasmodium falciparum protein kinase 5 0.0078 0.0375 0.3069
Entamoeba histolytica hypothetical protein 0.0072 0.0318 0.1189
Echinococcus multilocularis protein tyrosine kinase 0.0038 0.0007 0.0008
Brugia malayi C1-like domain containing protein 0.023 0.1788 0.3093
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0116 0.0416
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0245 0.028
Giardia lamblia Protein 21.1 0.0038 0.0007 0.000000045391
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0087 0.0455 0.0788
Loa Loa (eye worm) RGC/RGC protein kinase 0.0038 0.0007 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Loa Loa (eye worm) TK protein kinase 0.0038 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0525 0.0899
Trypanosoma brucei cdc2-related kinase 3 0.0078 0.0375 0.1405
Brugia malayi Protein kinase domain containing protein 0.0332 0.2736 0.4739
Entamoeba histolytica ankyrin repeat protein 0.0038 0.0007 0.000000041062
Echinococcus granulosus serine/threonine protein kinase 0.0177 0.1297 0.1297
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.004 0.0025 0.0072
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0126 0.082 0.3434
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0054 0.0156 0.0631
Loa Loa (eye worm) hypothetical protein 0.007 0.0297 0.0513
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0121 0.0778 0.0778
Onchocerca volvulus 0.0098 0.0565 0.1736
Entamoeba histolytica SH2 domain containing protein 0.006 0.0208 0.0769
Echinococcus granulosus natriuretic peptide receptor 1 0.0038 0.0007 0.0007
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0293 0.2381 0.4122
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0404 0.3406 0.3887
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0398 0.0869
Brugia malayi Hr1 repeat family protein 0.0316 0.2593 0.4491
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0455 0.0998
Brugia malayi hypothetical protein 0.0076 0.0354 0.0602
Entamoeba histolytica protein kinase, putative 0.004 0.0025 0.007
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.005 0.0116 0.0909
Brugia malayi putative serine/threonine kinase SADA gamma 0.008 0.0398 0.0678
Echinococcus multilocularis NCK adaptor protein 0.0096 0.0545 0.0622
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0136 0.0918 0.2027
Schistosoma mansoni hypothetical protein 0.0079 0.0384 0.0839
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.0846 0.1465
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0075 0.0345 0.0587
Trypanosoma cruzi aurora B kinase, putative 0.0155 0.1091 0.4578
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0069 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Schistosoma mansoni tyrosine kinase 0.009 0.0491 0.1078
Echinococcus granulosus CDC7 cell division cycle 7 0.0093 0.0517 0.0517
Echinococcus granulosus tyrosine protein kinase HCK 0.0136 0.0912 0.0912
Echinococcus granulosus tyrosine protein kinase Srms 0.0549 0.4759 0.4759
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.023 0.1788 0.3093
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0069 0.029 0.0331
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0155 0.1091 0.1091
Loa Loa (eye worm) hypothetical protein 0.0195 0.1463 0.2536
Brugia malayi Protein kinase domain containing protein 0.0196 0.147 0.2541
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Plasmodium falciparum calcium-dependent protein kinase 1 0.0114 0.0709 0.5859
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0056 0.0173 0.0299
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0056 0.0169 0.0361
Echinococcus multilocularis SH2 motif 0.006 0.0208 0.0238
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Giardia lamblia Kinase, STE STE20 0.0088 0.0465 0.1935
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0404 0.3406 0.3406
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0525 0.0899
Echinococcus multilocularis casein kinase I delta 0.0114 0.0712 0.0812
Entamoeba histolytica protein kinase, putative 0.0136 0.0918 0.348
Onchocerca volvulus 0.0098 0.0565 0.1736
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0129 0.0851 0.3227
Echinococcus granulosus Zinc finger DBF type 0.0113 0.0706 0.0706
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Schistosoma mansoni netrin receptor unc5 0.004 0.0026 0.0042
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1091 0.189
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0167 0.1205 1
Brugia malayi p70 ribosomal S6 kinase beta 0.031 0.2532 0.4384
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0175 0.1282 0.1463
Echinococcus granulosus tyrosine protein kinase Fyn 0.023 0.1786 0.1786
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0323 0.0703
Brugia malayi Protein kinase domain containing protein 0.0038 0.0007 0.000000018659
Echinococcus multilocularis SH2 domain containing adapter protein F 0.006 0.0208 0.0238
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0318 0.0318
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0712 0.2694
Schistosoma mansoni hypothetical protein 0.0127 0.0834 0.184
Echinococcus multilocularis tyrosine protein kinase Srms 0.0196 0.147 0.1677
Giardia lamblia Kinase, CMGC CDK 0.0078 0.0375 0.1553
Schistosoma mansoni tar DNA-binding protein 0.0062 0.023 0.0496
Loa Loa (eye worm) acetyltransferase 0.015 0.1042 0.1806
Loa Loa (eye worm) protein kinase domain-containing protein 0.023 0.1788 0.3099
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0075 0.0345 0.2821
Loa Loa (eye worm) hypothetical protein 0.0153 0.1078 0.1867
Schistosoma mansoni tyrosine-protein kinase zap-70 0.006 0.0208 0.0448
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0044 0.0058 0.0115
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0114 0.0709 0.2781
Echinococcus granulosus serine threonine protein kinase nrc 0.0167 0.1205 0.1205
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0069 0.029 0.1121
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0121 0.0778 0.0888
Schistosoma mansoni protein kinase 0.0038 0.0007 0.000000023914
Loa Loa (eye worm) hypothetical protein 0.0286 0.2307 0.4001
Echinococcus multilocularis mitogen activated protein kinase 11 0.017 0.1231 0.1405
Brugia malayi protein unc-22 0.0056 0.0173 0.0289
Schistosoma mansoni ephrin receptor 0.0045 0.0069 0.0138
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0123 0.0201
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1805 0.1805
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0712 0.1233
Loa Loa (eye worm) hypothetical protein 0.005 0.0115 0.0197
Echinococcus multilocularis Diacylglycerol kinase theta 0.0041 0.0036 0.0041
Plasmodium falciparum serine/threonine protein kinase 0.0086 0.0449 0.3689
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0384 0.3221 0.5581
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Plasmodium vivax casein kinase 1, putative 0.0114 0.0712 0.5882
Echinococcus multilocularis tyrosine protein kinase Blk 0.0196 0.147 0.1677
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0111 0.0232
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.008 0.0398 0.0688
Echinococcus multilocularis epidermal growth factor receptor 0.0126 0.0827 0.0944
Toxoplasma gondii AGC kinase 0.0075 0.0345 0.1339
Brugia malayi Protein kinase domain containing protein 0.0093 0.0517 0.0887
Onchocerca volvulus 0.0043 0.0049 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0345 0.0752
Loa Loa (eye worm) hypothetical protein 0.0076 0.0354 0.0611
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.035 0.1313
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.02 0.1512 0.262
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0056 0.0169 0.0169
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0038 0.0007 0.000000041062
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0072 0.0323 0.0323
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.8763 1
Entamoeba histolytica p21-activated kinase 0.0099 0.0571 0.2155
Brugia malayi serine/threonine-protein kinase 6 0.0155 0.1091 0.1882
Schistosoma mansoni hypothetical protein 0.0041 0.0036 0.0064
Schistosoma mansoni protein kinase subunit gamma 0.0259 0.2059 0.4566
Brugia malayi MAP kinase sur-1 0.0087 0.0455 0.0779
Onchocerca volvulus Serine\/threonine kinase homolog 0.0175 0.1282 0.3967
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0038 0.0007 0.001
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0136 0.0918 0.3847
Echinococcus granulosus RNA directed DNA polymerase 0.0044 0.0058 0.0058
Trypanosoma cruzi Protein kinase B 0.0177 0.1297 0.545
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis tyrosine protein kinase pr2 0.0038 0.0007 0.0008
Brugia malayi Protein kinase domain containing protein 0.0098 0.0565 0.0969
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Trypanosoma cruzi casein kinase, putative 0.0114 0.0712 0.2978
Brugia malayi serine/threonine-protein kinase PAK 7 0.0251 0.1981 0.3429
Onchocerca volvulus Tyrosine kinase homolog 0.0057 0.0185 0.0554
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.004 0.0025 0.007
Trypanosoma cruzi p21-activated kinase 3, putative 0.0054 0.0156 0.0631
Giardia lamblia Kinase, CDC7 0.0093 0.0517 0.2157
Loa Loa (eye worm) hypothetical protein 0.0071 0.0309 0.0533
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0318 0.0363
Loa Loa (eye worm) hypothetical protein 0.0199 0.1505 0.2609
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0404 0.3406 0.3406
Schistosoma mansoni hypothetical protein 0.0059 0.0198 0.0425
Brugia malayi hypothetical protein 0.005 0.0115 0.0187
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.0009 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0173 0.126 0.4788
Loa Loa (eye worm) hypothetical protein 0.0114 0.0709 0.1228
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1091 0.4141
Brugia malayi phosphoinositide-dependent protein kinase I 0.0084 0.0432 0.0738
Echinococcus multilocularis Immunoglobulin 0.0069 0.0292 0.0333
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.017 0.1231 0.4677
Giardia lamblia Aurora kinase 0.0155 0.1091 0.4578
Echinococcus granulosus protein kinase c eta type 0.0041 0.0036 0.0036
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Schistosoma mansoni hypothetical protein 0.0166 0.1194 0.2642
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0345 0.0394
Echinococcus granulosus serine:threonine kinase SAD 1 0.008 0.0398 0.0398
Echinococcus multilocularis nervana 2 0.0137 0.0922 0.1052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0125 0.0215
Schistosoma mansoni vav2 0.0111 0.0686 0.1511
Trichomonas vaginalis AGC family protein kinase 0.032 0.2624 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Echinococcus granulosus serine:threonine protein kinase N2 0.0316 0.2593 0.2593
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0089 0.0479 0.0479
Schistosoma mansoni protein kinase 0.0359 0.2993 0.6646
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0375 0.1405
Schistosoma mansoni serine/threonine kinase 0.0173 0.126 0.2788
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Loa Loa (eye worm) hypothetical protein 0.0047 0.0092 0.0157
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0088 0.0465 0.1935
Echinococcus multilocularis Immunoglobulin 0.0069 0.0292 0.0333
Echinococcus granulosus retinal guanylyl cyclase 2 0.0038 0.0007 0.0007
Onchocerca volvulus 0.0199 0.1505 0.4661
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0293 0.2374 0.2374
Brugia malayi Protein kinase domain containing protein 0.023 0.1788 0.3092
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0123 0.0798 0.1374
Loa Loa (eye worm) hypothetical protein 0.0395 0.3329 0.5773
Brugia malayi SH2 domain containing protein 0.0434 0.3686 0.6388
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0293 0.2374 0.2709
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0078 0.0375 0.1553
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0065 0.0252 0.0435
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0173 0.126 0.126
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0089 0.0479 0.0546
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.0918 0.348
Brugia malayi Protein kinase domain containing protein 0.02 0.1512 0.2613
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0266 0.2125 0.2425
Echinococcus multilocularis serine:threonine protein kinase 3 0.0278 0.2236 0.2552
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0478 0.1802
Trypanosoma cruzi casein kinase, putative 0.0114 0.0712 0.2978
Brugia malayi Cam kinase protein 1 0.0114 0.0709 0.1219
Brugia malayi STAT protein, DNA binding domain containing protein 0.006 0.0208 0.035
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0129 0.0851 0.3568
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0088 0.0465 0.1935
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0318 0.0693
Echinococcus granulosus casein kinase I delta 0.0114 0.0712 0.0712
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0038 0.0007 0.001
Trypanosoma cruzi NIMA-related kinase, putative 0.005 0.0116 0.046
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0565 0.0978
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0232 0.1805 0.313
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Loa Loa (eye worm) hypothetical protein 0.0056 0.0169 0.0292
Echinococcus granulosus serine:threonine protein kinase 0.0075 0.035 0.035
Leishmania major protein kinase A catalytic subunit isoform 2 0.0075 0.0345 0.1428
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.0007 0.001
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0044 0.0058 0.0067
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0077 0.037 0.037
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.004 0.0025 0.0077
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0075 0.0345 0.1428
Schistosoma mansoni protein kinase subunit beta 0.0067 0.0278 0.0603
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0125 0.0143
Echinococcus multilocularis neuroglian 0.0088 0.047 0.0536
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.008 0.0398 0.326
Entamoeba histolytica protein kinase, putative 0.0072 0.0323 0.1207
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0517 0.1951
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.006
Brugia malayi Protein kinase domain containing protein 0.0173 0.126 0.2175
Entamoeba histolytica protein kinase, putative 0.0173 0.126 0.4788
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0164 0.1174 0.4932
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0089 0.0478 0.1992
Onchocerca volvulus 0.006 0.0208 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0838 0.1849
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0154 0.1084 0.1237
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0208 0.0448
Schistosoma mansoni tyrosine kinase 0.0066 0.0263 0.0571
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1805 0.4003
Echinococcus granulosus unc 13 munc13 0.0043 0.0049 0.0049
Echinococcus granulosus activated cdc42 kinase 1 0.0038 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.023 0.1788 0.3963
Entamoeba histolytica protein kinase, putative 0.0114 0.0709 0.2683
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Echinococcus multilocularis cyclin dependent kinase 5 0.0078 0.0375 0.0427
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.1042 0.2304
Echinococcus granulosus protein kinase shaggy 0.0136 0.0918 0.0918
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0756 0.2864
Echinococcus granulosus hypothetical protein 0.0133 0.0891 0.0891
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.029 0.1081
Echinococcus granulosus NDR protein kinase 0.0173 0.126 0.126
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1658 0.3675
Loa Loa (eye worm) hypothetical protein 0.0043 0.0049 0.0082
Trichomonas vaginalis STE family protein kinase 0.0088 0.0465 0.175
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0125 0.0125
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.005 0.0116 0.0909
Schistosoma mansoni tyrosine kinase 0.0126 0.0827 0.1825
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0078 0.0375 0.1553
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.004 0.0025 0.0077
Brugia malayi loechrig isoform VII 0.0259 0.2059 0.3563
Echinococcus multilocularis mitogen activated protein kinase 3 0.0087 0.0455 0.052
Loa Loa (eye worm) hypothetical protein 0.006 0.0208 0.0359
Loa Loa (eye worm) TK/DDR protein kinase 0.0038 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0127 0.0834 0.1445
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0266 0.2125 0.3684
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.2374 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0129 0.0851 0.3568
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.2217 0.4919
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0177 0.1297 0.545
Echinococcus multilocularis calcium activated potassium channel 0.0109 0.0667 0.0761
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0384 0.3221 1
Echinococcus granulosus c-Jun N-terminal kinases 0.0286 0.2312 0.2312
Entamoeba histolytica protein kinase, putative 0.0155 0.1091 0.4141
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0398 0.0869
Loa Loa (eye worm) hypothetical protein 0.008 0.0398 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0173 0.037
Schistosoma mansoni patched 1 0.0051 0.0125 0.0263
Giardia lamblia Kinase, CMGC GSK 0.0136 0.0918 0.3847
Entamoeba histolytica hypothetical protein 0.0041 0.0036 0.011
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0069 0.029 0.1081
Brugia malayi RhoGAP domain containing protein 0.0041 0.0036 0.005
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0078 0.0375 0.0648
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0154 0.1084 0.1084
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0155 0.1091 0.9044
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0069 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0007 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Brugia malayi Protein kinase domain containing protein 0.0075 0.035 0.0597
Echinococcus granulosus growth factor receptor bound protein 2 0.0096 0.0545 0.0545
Entamoeba histolytica protein kinase, putative 0.0129 0.0851 0.3227
Loa Loa (eye worm) hypothetical protein 0.0062 0.0232 0.04
Loa Loa (eye worm) TK/INSR protein kinase 0.009 0.0491 0.085
Onchocerca volvulus 0.0098 0.0565 0.1736
Echinococcus granulosus tyrosine kinase 0.0196 0.147 0.147
Loa Loa (eye worm) STAT protein 0.006 0.0208 0.0359
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0259 0.2059 0.2349
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0208 0.0208
Echinococcus granulosus protein kinase C gamma type 0.0218 0.1681 0.1681
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Schistosoma mansoni hypothetical protein 0.0079 0.0384 0.0839
Brugia malayi Protein kinase domain containing protein 0.0657 0.5766 1
Trypanosoma cruzi cdc2-related kinase 3 0.0078 0.0375 0.1553
Brugia malayi cell division control protein 2 homolog 0.0078 0.0375 0.0639
Echinococcus multilocularis protein kinase shaggy 0.0136 0.0918 0.1047
Echinococcus granulosus mitogen activated protein kinase 3 0.0087 0.0455 0.0455
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0432 0.1625
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Brugia malayi integrin-linked kinase 0.0038 0.0007 0.000000018659
Plasmodium falciparum NIMA related kinase 4 0.005 0.0116 0.0909
Brugia malayi SH2 domain containing protein 0.006 0.0208 0.035
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0053 0.0143 0.0522
Trichomonas vaginalis AGC family protein kinase 0.0053 0.0143 0.0522
Echinococcus multilocularis geminin 0.0166 0.1194 0.1363
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0293 0.2381 0.4128
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0137 0.0922 0.0922
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0398 0.1493
Schistosoma mansoni tar DNA-binding protein 0.0062 0.023 0.0496
Loa Loa (eye worm) hypothetical protein 0.0158 0.1119 0.194
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.2374 0.5268
Schistosoma mansoni protein kinase 0.0359 0.2993 0.6646
Loa Loa (eye worm) thyroid receptor interactor 0.0118 0.0747 0.1294
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0114 0.0709 0.0709
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.023 0.1786 0.2038
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0432 0.1625
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0432 0.1625
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0774 0.1706
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1805 0.1805
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0284 0.2297 0.2622
Entamoeba histolytica protein kinase, putative 0.009 0.0491 0.1851
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0756 0.1302
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0478 0.1049
Echinococcus multilocularis Rac GTPase activating protein 1 0.0041 0.0036 0.0041
Entamoeba histolytica protein kinase, putative 0.0115 0.0722 0.2733
Brugia malayi Protein kinase domain containing protein 0.0098 0.0565 0.0969
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0455 0.1895
Echinococcus multilocularis N chimaerin 0.0101 0.0594 0.0678
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0233 0.0502
Schistosoma mansoni protein kinase C mu 0.023 0.1788 0.3964
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0164 0.1174 0.4932
Giardia lamblia Kinase, AGC AKT 0.0123 0.0798 0.3343
Brugia malayi Protein kinase c protein 2 0.0117 0.074 0.1272
Giardia lamblia Kinase, CMGC DYRK 0.0089 0.0478 0.1992
Loa Loa (eye worm) hypothetical protein 0.0076 0.0354 0.0611
Echinococcus granulosus N chimaerin 0.0101 0.0594 0.0594
Brugia malayi serine/threonine protein kinase 6 0.0155 0.1091 0.1882
Echinococcus multilocularis ephrin type A receptor 4 A 0.0109 0.0665 0.0759
Loa Loa (eye worm) hypothetical protein 0.0085 0.0444 0.0767
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.001
Echinococcus granulosus Vam6:Vps39 protein 0.0056 0.0169 0.0169
Echinococcus granulosus expressed conserved protein 0.0112 0.0689 0.0689
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0154 0.1084 0.1237
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2374 0.9046
Echinococcus multilocularis AMPK beta subunit 0.0126 0.082 0.0936
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0075 0.0345 0.1292
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0894 0.339
Echinococcus granulosus retinal guanylyl cyclase 2 0.0038 0.0007 0.0007
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0084 0.0432 0.0432
Brugia malayi Protein kinase domain containing protein 0.0129 0.0851 0.1467
Entamoeba histolytica protein kinase domain containing protein 0.0155 0.1091 0.4141
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0043 0.0049 0.0055
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0712 0.2694
Brugia malayi map kinase activated protein kinase protein 2 0.043 0.3649 0.6324
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0114 0.0709 0.0809
Echinococcus granulosus tyrosine protein kinase pr2 0.0038 0.0007 0.0007
Brugia malayi SH2 domain containing protein 0.0098 0.0565 0.0969
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0235 0.0873
Brugia malayi protein kinase C II. 0.0216 0.1658 0.2868
Schistosoma mansoni adapter molecule crk 0.0094 0.0525 0.1152
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0101 0.0594 0.1028
Trypanosoma cruzi NIMA-related kinase, putative 0.004 0.0025 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0432 0.0946
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0026 0.0033
Entamoeba histolytica hypothetical protein 0.0072 0.0318 0.1189
Echinococcus granulosus casein kinase I alpha 0.0114 0.0712 0.0712
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0126 0.082 0.142
Loa Loa (eye worm) TK protein kinase 0.0196 0.147 0.2547
Echinococcus granulosus casein kinase I gamma 0.023 0.1788 0.1788
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0078 0.0375 0.0375
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1091 0.4141
Echinococcus granulosus dual specificity 0.0089 0.0478 0.0478
Leishmania major protein kinase A catalytic subunit 0.0075 0.0345 0.1428

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) = 2.12 uM PUBCHEM_BIOASSAY: Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504586] ChEMBL. No reference
Potency (functional) = 0.2239 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.2593 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 0.2617 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.3981 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.4109 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 0.5012 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.5221 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.122 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.0596 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 2.3934 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.1735 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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