Detailed information for compound 145380

Basic information

Technical information
  • TDR Targets ID: 145380
  • Name: dodecyl 2-(1-methylpiperidin-1-ium-1-yl)ethyl phosphate
  • MW: 391.526 | Formula: C20H42NO4P
  • H donors: 0 H acceptors: 2 LogP: 5.38 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCOP(=O)(OCC[N+]1(C)CCCCC1)[O-]
  • InChi: 1S/C20H42NO4P/c1-3-4-5-6-7-8-9-10-11-15-19-24-26(22,23)25-20-18-21(2)16-13-12-14-17-21/h3-20H2,1-2H3
  • InChiKey: YYOKQCIRJQDCHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • dodecyl 2-(1-methyl-1-piperidin-1-iumyl)ethyl phosphate
  • lauryl 2-(1-methylpiperidin-1-ium-1-yl)ethyl phosphate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0072 0.0072
Echinococcus granulosus dna polymerase eta 0.0039 0.0102 0.0158
Schistosoma mansoni amine GPCR 0.0026 0.005 0.0077
Leishmania major cytochrome P450 reductase, putative 0.028 0.1038 0.4539
Echinococcus granulosus beta 1 syntrophin 0.0014 0.0004 0.0006
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0354 0.1326 0.2059
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0121 0.042 0.3563
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0036 0.009 0.0139
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.005 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0055 0.0238
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0037 0.0058
Entamoeba histolytica hypothetical protein, conserved 0.1672 0.6437 1
Trypanosoma cruzi reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0026 0.005 0.013
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0064 0.0201 0.0201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Echinococcus granulosus pdz domain containing protein 0.0014 0.0004 0.0006
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.1044 0.4775
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis partitioning defective 3 0.0014 0.0004 0.0004
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0007
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0071 0.0226 0.2757
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0047 0.0204
Schistosoma mansoni hypothetical protein 0.0705 0.2684 0.417
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0051 0.0079
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Leishmania major NADH-dependent fumarate reductase-like protein 0.0036 0.009 0.0392
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0065 0.0203 0.0887
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0208 0.0324
Trypanosoma cruzi Sphingosine kinase 0.0065 0.0203 0.0887
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0053 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0021 0.0089
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis ligand of numb protein x 2 0.0014 0.0004 0.0004
Echinococcus granulosus glutamate receptor interacting protein 1 0.0014 0.0004 0.0006
Echinococcus granulosus cell polarity protein 0.0014 0.0004 0.0007
Brugia malayi Guanylate kinase family protein 0.0014 0.0004 0.0009
Onchocerca volvulus 0.0019 0.0024 0.0061
Echinococcus granulosus segment polarity protein dishevelled 0.0023 0.004 0.0061
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0121 0.042 0.192
Schistosoma mansoni pdz domain containing protein 0.0014 0.0004 0.0005
Brugia malayi RasGEF domain containing protein 0.002 0.0029 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.005 0.0078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0024 0.0037
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Onchocerca volvulus 0.0239 0.0877 0.2285
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0005 0.0018
Brugia malayi glutathione reductase 0.014 0.0493 0.1285
Echinococcus granulosus paired box protein pax 6 0.0019 0.0025 0.0039
Echinococcus granulosus survival motor neuron protein 1 0.0254 0.0936 0.1454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Schistosoma mansoni NADPH flavin oxidoreductase 0.0159 0.0569 0.0883
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.005 0.0078
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0021 0.0033
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0005 0.0018
Giardia lamblia GTOR 0.0018 0.0021 0.0196
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.005 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0226 0.0986
Entamoeba histolytica type A flavoprotein, putative 0.0121 0.042 0.0651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.014 0.0493 0.0765
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0079 0.0122
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Onchocerca volvulus 0.0026 0.005 0.013
Plasmodium falciparum JmjC domain-containing protein, putative 0.0039 0.0103 0.0467
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0141 0.0141
Brugia malayi hypothetical protein 0.0065 0.0203 0.0529
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0004 0.0027
Schistosoma mansoni hypothetical protein 0.086 0.3287 0.5106
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0025 0.0025
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0021 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0141 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0125
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.005 0.005
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.004 0.0103
Echinococcus granulosus paired box gene 3/7 (eyeless, eyegone, twin of eyeless) 0.0019 0.0025 0.0039
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0005 0.0007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0066 0.0206 0.0897
Trypanosoma cruzi PAB1-binding protein , putative 0.0154 0.0549 0.2401
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0312 0.1364
Mycobacterium tuberculosis Conserved protein 0.1672 0.6437 1
Loa Loa (eye worm) ceramide kinase 0.0065 0.0203 0.0316
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Echinococcus multilocularis pdz domain containing protein 0.0014 0.0004 0.0004
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Echinococcus multilocularis cytochrome b5 reductase 4 0.0036 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0042 0.0115 0.0179
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0312 0.1364
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0021 0.0032
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0121 0.042 0.1835
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0024 0.0024
Leishmania major reductase, putative 0.0036 0.009 0.0392
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0206 0.0897
Trichomonas vaginalis diacylglycerol kinase, putative 0.0065 0.0203 0.1723
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0094 0.1146
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0004 0.0005
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.0001 0.0001
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0025 0.0064
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0312 0.0813
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0052 0.008
Echinococcus multilocularis dna polymerase eta 0.0039 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0137
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0316 0.1177 0.1177
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0051 0.0051
Loa Loa (eye worm) Smad1 0.005 0.0144 0.0224
Brugia malayi Smad1 0.005 0.0144 0.0374
Entamoeba histolytica hypothetical protein 0.0221 0.0808 0.1254
Schistosoma mansoni hypothetical protein 0.0705 0.2684 0.417
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.005 0.0077
Echinococcus multilocularis phd:f box containing protein 0.0039 0.0103 0.0103
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0053 0.0447
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.004 0.0063
Loa Loa (eye worm) fibroinase 0.0019 0.0024 0.0037
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0094 0.0796
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0239 0.2024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0141 0.0217
Echinococcus multilocularis amyloid beta A4 protein 0.0014 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Echinococcus granulosus Diacylglycerol kinase zeta 0.0065 0.0203 0.0316
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0017 0.0025
Onchocerca volvulus 0.0074 0.0239 0.0621
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0018
Schistosoma mansoni cpg binding protein 0.006 0.0185 0.0286
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0021 0.0021
Trichomonas vaginalis hypothetical protein 0.0017 0.0017 0.0138
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.004 0.004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0167 0.0258
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0065 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Trichomonas vaginalis esterase, putative 0.0074 0.0239 0.2024
Loa Loa (eye worm) hypothetical protein 0.0223 0.0818 0.127
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0139 0.0604
Echinococcus multilocularis paired box protein pax 1 0.0019 0.0025 0.0025
Brugia malayi cell junction protein LIN-7 0.0014 0.0004 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0024 0.0024
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0066 0.0206 0.032
Chlamydia trachomatis sulfite reductase 0.0195 0.0708 1
Brugia malayi Nuclear hormone receptor E75 0.0023 0.004 0.0103
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0014 0.0004 0.0005
Echinococcus multilocularis partitioning defective protein 6 0.0014 0.0004 0.0004
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0036 0.009 0.0234
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0135 0.0588
Schistosoma mansoni opsin-like receptor 0.0026 0.005 0.0077
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0135 0.0209
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.005 0.0077
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Schistosoma mansoni DNA polymerase eta 0.0039 0.0102 0.0157
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Brugia malayi G-protein coupled receptor 0.0026 0.005 0.013
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0026 0.005 0.005
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0182 0.0282
Brugia malayi sulfakinin receptor protein 0.0026 0.005 0.013
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0025 0.0064
Echinococcus granulosus methionine synthase reductase 0.0195 0.0708 0.11
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0339 0.0526
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0065 0.0203 0.0887
Schistosoma mansoni biogenic amine receptor 0.0026 0.005 0.0077
Echinococcus granulosus partitioning defective 3 0.0014 0.0004 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0443
Echinococcus multilocularis neuropeptide receptor A26 0.0026 0.005 0.005
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.005 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis mothers against decapentaplegic 2 0.0022 0.0037 0.0037
Brugia malayi PDZ domain containing protein 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0239 0.037
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.004 0.0062
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0141 0.0217
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0208 0.0324
Entamoeba histolytica type A flavoprotein, putative 0.0121 0.042 0.0651
Onchocerca volvulus Arc homolog 0.0014 0.0004 0.0009
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.004 0.0103
Loa Loa (eye worm) hypothetical protein 0.0148 0.0524 0.0814
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0077
Onchocerca volvulus Alhambra homolog 0.0121 0.0421 0.1097
Loa Loa (eye worm) glutathione reductase 0.014 0.0493 0.0766
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.005 0.013
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0073
Schistosoma mansoni leucine-rich repeat protein 0.0014 0.0004 0.0006
Echinococcus granulosus tachykinin peptides receptor 99D 0.0026 0.005 0.0078
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.005 0.005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0135 0.0209
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Treponema pallidum ferredoxin-NADP(+) reductase subunit alpha 0.0036 0.009 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0135 0.0209
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0226 0.035
Echinococcus granulosus tar DNA binding protein 0.0325 0.1213 0.1884
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Brugia malayi diaphorase 0.0036 0.009 0.0234
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0148 0.0524 0.0524
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0239 0.0371
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0103 0.0159
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0051 0.0131
Loa Loa (eye worm) hypothetical protein 0.0208 0.0757 0.1176
Loa Loa (eye worm) jmjC domain-containing protein 0.015 0.0533 0.0829
Loa Loa (eye worm) histone methyltransferase 0.002 0.0028 0.0043
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0037 0.0058
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0312 0.0813
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Echinococcus multilocularis smad 0.005 0.0144 0.0144
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.005 0.005
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0014 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0041 0.0109 0.0168
Echinococcus granulosus segment polarity protein dishevelled 0.0023 0.004 0.0061
Toxoplasma gondii cathepsin CPL 0.0019 0.0024 0.0284
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus pdz domain containing protein 0.0014 0.0004 0.0006
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0094 0.0145
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.005 0.0077
Echinococcus granulosus g protein coupled receptor 0.0026 0.005 0.0078
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0089 0.023
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0024 0.0024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.005 0.0078
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.004 0.0062
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0239 0.037
Echinococcus multilocularis survival motor neuron protein 1 0.0254 0.0936 0.0936
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0072 0.0111
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.005 0.005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0103 0.0446
Echinococcus granulosus microtubule associated protein 2 0.0691 0.2633 0.409
Trypanosoma cruzi p450 reductase, putative 0.0316 0.1177 0.5149
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.004 0.0103
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0125
Loa Loa (eye worm) paired box protein 0.0019 0.0025 0.0039
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0063 0.0097
Echinococcus multilocularis pdz domain containing protein 0.0014 0.0004 0.0004
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.005 0.0078
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0135 0.0209
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0048 0.0139 0.0604
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0135 0.0615
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0005 0.0019
Echinococcus granulosus carbonic anhydrase 0.0223 0.0818 0.127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0024 0.0061
Schistosoma mansoni pdz and lim domain protein 0.0014 0.0004 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0026 0.005 0.005
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0014 0.0004 0.0004
Schistosoma mansoni opsin-like receptor 0.0026 0.005 0.0077
Echinococcus multilocularis importin 5 0.0017 0.0017 0.0017
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0223 0.0818 0.2132
Brugia malayi Inositol-1 0.0037 0.0094 0.0244
Schistosoma mansoni diacylglycerol kinase theta 0.0065 0.0203 0.0315
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0141 0.0217
Loa Loa (eye worm) latrophilin receptor protein 2 0.0148 0.0524 0.0814
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0135 0.0588
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0239 0.2024
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0021 0.0089
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0065 0.0203 0.0316
Mycobacterium ulcerans lipase LipD 0.0074 0.0239 0.037
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0333 0.0517
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0014 0.0004 0.0006
Echinococcus granulosus somatostatin receptor 0.0026 0.005 0.0078
Loa Loa (eye worm) RNA binding protein 0.0325 0.1213 0.1884
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0135 0.0209
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0137
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Schistosoma mansoni importin beta-1 0.009 0.0301 0.0466
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Onchocerca volvulus 0.0019 0.0024 0.0061
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0234 0.1987
Echinococcus granulosus importin 5 0.0017 0.0017 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0026 0.005 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0026 0.0052 0.0133
Echinococcus multilocularis musashi 0.0026 0.0052 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.014 0.0495 0.0495
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0053
Schistosoma mansoni hypothetical protein 0.0148 0.0524 0.0813
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Onchocerca volvulus 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0099 0.0333 0.0518
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni transcription factor LCR-F1 0.0221 0.0808 0.1254
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0021 0.0032
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0089 0.1241
Brugia malayi jmjC domain containing protein 0.0397 0.1491 0.3889
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0021 0.0094
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0319 0.1188 0.1844
Echinococcus multilocularis segment polarity protein dishevelled 0.0023 0.004 0.004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0102 0.086
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0072 0.0111
Echinococcus granulosus sphingosine kinase 1 0.1672 0.6437 1
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0144 0.0224
Mycobacterium ulcerans beta-lactamase 0.0074 0.0239 0.037
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0144 0.0224
Echinococcus granulosus lysosomal alpha glucosidase 0.032 0.1191 0.185
Schistosoma mansoni tight junction protein 0.0014 0.0004 0.0005
Schistosoma mansoni Smad4 0.0022 0.0037 0.0057
Schistosoma mansoni MAGUK homolog 0.0014 0.0005 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.0071 0.0226 0.0588
Echinococcus granulosus tumor protein p63 0.0338 0.1264 0.1964
Echinococcus granulosus nuclear factor of activated T cells 5 0.0064 0.0201 0.0312
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0312 0.0312
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0234 0.1987
Trichomonas vaginalis diacylglycerol kinase, putative 0.0065 0.0203 0.1723
Schistosoma mansoni amine GPCR 0.0026 0.005 0.0077
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0121 0.0421 0.0653
Echinococcus granulosus pdz domain containing protein 0.0014 0.0004 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Leishmania major trypanothione reductase 0.014 0.0493 0.2155
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0013 0.0021
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0048 0.0139 0.1689
Brugia malayi jmjC domain containing protein 0.015 0.0533 0.139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Brugia malayi beta-lactamase 0.0074 0.0239 0.0621
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0239 0.037
Brugia malayi jmjC domain containing protein 0.0039 0.0103 0.0266
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Schistosoma mansoni jumonji domain containing protein 0.0315 0.1175 0.1824
Trichomonas vaginalis sphingosine kinase, putative 0.0065 0.0203 0.1723
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0089 0.0136
Loa Loa (eye worm) hypothetical protein 0.0043 0.0118 0.0183
Echinococcus multilocularis carbonic anhydrase II 0.0602 0.2286 0.2286
Echinococcus multilocularis carbonic anhydrase 0.0223 0.0818 0.0818
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0182 0.0793
Echinococcus granulosus JmjC domain containing protein 4 0.0039 0.0103 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0239 0.1042
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0072 0.0112
Echinococcus granulosus expressed conserved protein 0.0093 0.031 0.0482
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Leishmania major hypothetical protein, conserved 0.0154 0.0549 0.2401
Mycobacterium tuberculosis Probable reductase 0.0319 0.1188 0.1844
Onchocerca volvulus 0.0019 0.0024 0.0061
Schistosoma mansoni cytochrome P450 reductase 0.0316 0.1177 0.1828
Trichomonas vaginalis glutathione reductase, putative 0.0048 0.0139 0.1173
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0485 0.0752
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0226 0.1914
Schistosoma mansoni paired box protein pax-6 0.0019 0.0025 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0021 0.0094
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Brugia malayi Gooseberry protein 0.0019 0.0025 0.0064
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0121 0.042 0.1835
Brugia malayi flavodoxin family protein 0.0121 0.042 0.1094
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0014 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0026 0.005 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0024 0.0102
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0195 0.0708 0.1099
Brugia malayi ecdysone receptor 0.0023 0.004 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0053 0.0447
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0141 0.0141
Echinococcus multilocularis microtubule associated protein 2 0.0691 0.2633 0.2633
Onchocerca volvulus 0.0014 0.0004 0.0009
Trichomonas vaginalis maltase-glucoamylase, putative 0.0071 0.0226 0.1914
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.0014 0.0004 0.0004
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0065 0.0203 0.1723
Loa Loa (eye worm) isocitrate dehydrogenase 0.0066 0.0206 0.032
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0024 0.0036
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0021 0.0094
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0005 0.0052
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Schistosoma mansoni ran 0.0066 0.0208 0.0323
Echinococcus multilocularis Partitioning defective 3 protein B 0.0014 0.0004 0.0004
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0014 0.0004 0.0005
Brugia malayi 9ORF binding protein 1 0.0014 0.0004 0.0009
Loa Loa (eye worm) DR-78 0.0023 0.004 0.0063
Schistosoma mansoni ran 0.0066 0.0208 0.0323
Echinococcus multilocularis serotonin receptor 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus MAGUK p55 subfamily 0.0014 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0161
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0017 0.0199
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0079
Toxoplasma gondii thioredoxin reductase 0.014 0.0493 0.6025
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0089
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0072 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0014 0.0005 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0103 0.0446
Leishmania major NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis tar DNA binding protein 0.0325 0.1213 0.1213
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0005 0.0052
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0021 0.0174
Echinococcus multilocularis isocitrate dehydrogenase 0.0066 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.008
Leishmania major DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0024 0.0037
Treponema pallidum NADH oxidase 0.0048 0.0139 0.0632
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.0001 0.0001
Echinococcus granulosus multiple pdz domain protein 0.0014 0.0004 0.0006
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.0014 0.0004 0.0006
Onchocerca volvulus 0.0019 0.0024 0.0061
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0182 0.0282
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0602 0.2286 0.355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Schistosoma mansoni discs large 0.0014 0.0004 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0141 0.0365
Echinococcus multilocularis neurabin 1 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Onchocerca volvulus 0.0074 0.0239 0.0621
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0017 0.0026
Onchocerca volvulus 0.0014 0.0004 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0055 0.0238
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0053 0.0447
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0039
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Schistosoma mansoni hypothetical protein 0.0963 0.3685 0.5724
Brugia malayi ecdysteroid receptor 0.0049 0.0141 0.0365
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.1038 0.1612
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0083
Onchocerca volvulus Big bang homolog 0.0014 0.0004 0.0009
Echinococcus multilocularis fmrfamide receptor 0.0026 0.005 0.005
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0316 0.1177 0.5149
Onchocerca volvulus 0.0026 0.005 0.013
Plasmodium falciparum diacylglycerol kinase, putative 0.0065 0.0203 0.0928
Loa Loa (eye worm) ctsf protein 0.0019 0.0024 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Plasmodium vivax flavodoxin domain containing protein 0.028 0.1038 0.4749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0047 0.0397
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0208 0.0908
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0048 0.0139 0.0214
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Leishmania major NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.005 0.0078
Brugia malayi G-protein coupled receptor 0.0026 0.005 0.013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Echinococcus multilocularis tight junction protein ZO 3 0.0014 0.0004 0.0004
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0024 0.0037
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0229 0.1
Schistosoma mansoni ap endonuclease 0.0018 0.0021 0.0032
Schistosoma mansoni paired box protein pax-6 0.0019 0.0025 0.0038
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0018
Mycobacterium tuberculosis Conserved protein 0.0074 0.0239 0.037
Brugia malayi jmjC domain containing protein 0.0039 0.0103 0.0266
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Echinococcus multilocularis sphingosine kinase 1 0.1672 0.6437 0.6437
Loa Loa (eye worm) PHD-finger family protein 0.0121 0.0421 0.0654
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0141 0.0141
Echinococcus multilocularis segment polarity protein dishevelled 0.0023 0.004 0.004
Schistosoma mansoni diacylglycerol kinase theta 0.0065 0.0203 0.0315
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0135 0.0209
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.0014 0.0004 0.0006
Onchocerca volvulus 0.0026 0.005 0.013
Onchocerca volvulus 0.0014 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0041 0.0109 0.0168
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Schistosoma mansoni ap endonuclease 0.0018 0.0021 0.0032
Mycobacterium ulcerans hypothetical protein 0.0047 0.0135 0.0209
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0001 0.0001
Onchocerca volvulus 0.006 0.0185 0.0481
Schistosoma mansoni coup transcription factor 0.0049 0.0141 0.0217
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0239 0.2024
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0141 0.0218
Onchocerca volvulus 0.0185 0.0668 0.1741
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.005 0.0078
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0021 0.0033
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0036 0.009 0.009
Echinococcus granulosus ligand of numb protein x 2 0.0014 0.0004 0.0006
Loa Loa (eye worm) guanylate kinase 0.0014 0.0004 0.0006
Brugia malayi N-terminal motif family protein 0.0186 0.0673 0.1754
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0319 0.1188 0.1844
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.028 0.1038 0.8815
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0223 0.0818 0.2132
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0182 0.0182
Brugia malayi gamma-syntrophin-like protein SYN2 0.0014 0.0004 0.0009
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.005 0.0077
Echinococcus granulosus thioredoxin glutathione reductase 0.014 0.0495 0.0769
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0024 0.0061
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.005 0.0077
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0482 0.182 0.2827
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0102 0.0157
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0066 0.0206 0.0319
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0047 0.0204
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.004 0.0063
Trypanosoma cruzi p450 reductase, putative 0.0036 0.009 0.0392
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0239 0.037
Onchocerca volvulus 0.0026 0.005 0.013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0239 0.037
Echinococcus granulosus pdz domain containing protein 0.0014 0.0004 0.0006
Trypanosoma brucei unspecified product 0.0039 0.0102 0.0443
Schistosoma mansoni sphingosine kinase A B 0.1672 0.6437 1
Loa Loa (eye worm) cell junction protein LIN-7 0.0014 0.0004 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0141 0.0365
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi Peripheral plasma membrane protein CASK 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Probable monooxygenase 0.0036 0.009 0.0139
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0005 0.0007
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0014 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0397 0.1491 0.1491
Plasmodium vivax thioredoxin reductase, putative 0.014 0.0493 0.2254
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0014 0.0005 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Onchocerca volvulus 0.0019 0.0024 0.0061
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0602 0.2286 0.355
Schistosoma mansoni Patj homolog 0.0014 0.0004 0.0005
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Diacylglycerol kinase 0.0065 0.0203 0.0315
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0467 0.1762 0.2738
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0017 0.0018 0.0076
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0021 0.025
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.005 0.013
Schistosoma mansoni alpha-glucosidase 0.0275 0.1018 0.158
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0013 0.0013
Brugia malayi Eye-specific diacylglycerol kinase 0.0065 0.0203 0.0529
Echinococcus multilocularis geminin 0.0705 0.2684 0.2684
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0141 0.0217
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0066 0.0206 0.0939
Loa Loa (eye worm) hypothetical protein 0.0154 0.0549 0.0853
Onchocerca volvulus 0.005 0.0143 0.0371
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0397 0.1491 0.2317
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0047 0.0074
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0021 0.0089
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.004 0.004
Onchocerca volvulus 0.0026 0.005 0.013
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0135 0.0209
Echinococcus granulosus protein lin 7 B 0.0014 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0048 0.0139 0.1951
Loa Loa (eye worm) MH2 domain-containing protein 0.073 0.2785 0.4326
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0021 0.009
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Schistosoma mansoni alpha-glucosidase 0.0275 0.1018 0.158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi Melatonin receptor type 1A 0.0026 0.005 0.013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0152 0.0394
Echinococcus multilocularis methionine synthase reductase 0.0195 0.0708 0.0708
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.028 0.1038 0.1613
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Toxoplasma gondii NADPH-glutathione reductase 0.0048 0.0139 0.1689
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.005 0.0078
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0148 0.0524 0.0814
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0036 0.009 0.0139
Echinococcus multilocularis jumonji domain containing protein 0.0169 0.0605 0.0605
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0182 0.0282
Echinococcus multilocularis mothers against decapentaplegic 6 0.0022 0.0037 0.0037
Echinococcus granulosus MAGUK p55 subfamily 0.0014 0.0004 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0319 0.1188 0.1844
Schistosoma mansoni cell polarity protein 0.0014 0.0004 0.0005
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0602 0.2286 0.5962
Leishmania major cathepsin L-like protease 0.0019 0.0024 0.0102
Schistosoma mansoni jumonji/arid domain-containing protein 0.015 0.0533 0.0828
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.005 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.005 0.005
Schistosoma mansoni maguk P55 subfamily member 26 0.0014 0.0004 0.0005
Plasmodium falciparum ferredoxin--NADP reductase 0.0036 0.009 0.041
Brugia malayi PDZ-domain protein scribble 0.0014 0.0004 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus granulosus hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Onchocerca volvulus 0.0031 0.0072 0.0186
Brugia malayi nuclear receptor RXR 0.0026 0.0051 0.0131
Echinococcus granulosus Smad4 0.005 0.0144 0.0224
Toxoplasma gondii isocitrate dehydrogenase 0.0066 0.0206 0.2509
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Brugia malayi Dopamine receptor 0.0026 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0141 0.0218
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.005 0.0078
Plasmodium falciparum thioredoxin reductase 0.0048 0.0139 0.0632
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0024 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0182 0.2218
Giardia lamblia PHD finger protein 15 0.0121 0.0421 0.4031
Brugia malayi hypothetical protein 0.0026 0.0051 0.0131
Plasmodium falciparum nitric oxide synthase, putative 0.0316 0.1177 0.5387
Mycobacterium ulcerans diacylglycerol kinase 0.0065 0.0203 0.0315
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0034 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Onchocerca volvulus 0.0014 0.0004 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.005 0.0078
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0214
Echinococcus multilocularis GPCR, family 2 0.0148 0.0524 0.0524
Giardia lamblia DINP protein human, muc B family 0.0039 0.0102 0.097
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0229 0.1
Onchocerca volvulus Retinal homeobox protein Rx homolog 0.0019 0.0025 0.0064
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.004 0.0103
Schistosoma mansoni histamine h1 receptor 0.0026 0.005 0.0077
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0024 0.0106
Trypanosoma cruzi PAB1-binding protein , putative 0.0154 0.0549 0.2401
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.005 0.0077
Echinococcus granulosus jumonji domain containing protein 0.0169 0.0605 0.094
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0121 0.042 0.1835
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0485 0.0752
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0206 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0141 0.0365
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0223 0.0818 0.1269
Trypanosoma brucei diacylglycerol kinase, putative 0.0065 0.0203 0.0887
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0065 0.0203 0.2482
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.1038 0.1038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.005 0.0078
Leishmania major importin beta-1 subunit, putative 0.0073 0.0234 0.1023
Loa Loa (eye worm) oxidoreductase 0.0014 0.0005 0.0008
Schistosoma mansoni cpg binding protein 0.0064 0.0198 0.0307
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0602 0.2286 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0043 0.0116 0.018
Brugia malayi Bromodomain containing protein 0.0121 0.0421 0.1097
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.005 0.005
Toxoplasma gondii flavodoxin domain-containing protein 0.0157 0.0559 0.6838
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0205 0.0894
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.017 0.0739
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0005 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0023 0.004 0.0101
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.005 0.0077
Schistosoma mansoni lim domain 0.0014 0.0004 0.0005
Echinococcus granulosus amyloid beta A4 protein 0.0014 0.0004 0.0006
Schistosoma mansoni cpg binding protein 0.0064 0.0198 0.0307
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0004
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.005 0.0078
Brugia malayi Neurabin protein 1 0.0014 0.0004 0.0009
Onchocerca volvulus 0.0014 0.0004 0.0009
Echinococcus granulosus cpg binding protein 0.0064 0.0198 0.0308
Schistosoma mansoni adenoreceptor 0.0026 0.005 0.0077
Onchocerca volvulus 0.0014 0.0005 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0072 0.0872
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0103 0.0159
Trypanosoma brucei NADH-dependent fumarate reductase 0.0036 0.009 0.0392
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0014 0.0004 0.0009
Echinococcus multilocularis Smad4 0.005 0.0144 0.0144
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.005 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0141 0.0365
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0239 0.037
Loa Loa (eye worm) hypothetical protein 0.0298 0.1108 0.1721
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0021 0.0053
Brugia malayi intermediate filament protein 0.0026 0.0052 0.0133
Schistosoma mansoni discs lost-related 0.0014 0.0004 0.0005
Schistosoma mansoni cell polarity protein 0.0014 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Echinococcus granulosus geminin 0.0705 0.2684 0.417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0208 0.0908
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.013 0.1098
Schistosoma mansoni amine GPCR 0.0026 0.005 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Schistosoma mansoni sap-97 0.0014 0.0004 0.0005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.005 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0239 0.1042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0135 0.0209
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.0014 0.0004 0.0004
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0021 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.005 0.0078
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0148 0.0524 0.1365
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.005 0.0077
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.005 0.005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.032 0.1191 0.185
Trichomonas vaginalis maltase-glucoamylase, putative 0.0026 0.0053 0.0447
Loa Loa (eye worm) diaphorase 0.0036 0.009 0.014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0216
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0239 0.0621
Echinococcus granulosus multiple pdz domain protein 0.0014 0.0004 0.0006
Echinococcus multilocularis multiple pdz domain protein 0.0014 0.0004 0.0004
Schistosoma mansoni afadin (af-6 protein) 0.0014 0.0004 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0141 0.0217
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.005 0.005
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0119 0.0541
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0229 0.1
Echinococcus multilocularis disks large 3 0.0014 0.0004 0.0004
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.005 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0026 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0021 0.009
Schistosoma mansoni hypothetical protein 0.0041 0.0109 0.0168
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0005 0.0018
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0182 0.0283
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0055 0.0238
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Leishmania major alpha glucosidase II subunit, putative 0.0071 0.0226 0.0986
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0141 0.0218
Mycobacterium tuberculosis Probable oxidoreductase 0.0354 0.1326 0.2059
Brugia malayi PDZ domain containing protein 0.0014 0.0004 0.0009
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Echinococcus multilocularis partitioning defective 3 0.0014 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0094 0.0796
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0039 0.0103 0.0158
Loa Loa (eye worm) beta-lactamase 0.0074 0.0239 0.0371
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0141 0.0217
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0208 0.095
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0065 0.0203 0.2482
Echinococcus multilocularis pdz domain containing protein 0.0014 0.0004 0.0004
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0019
Onchocerca volvulus 0.0026 0.005 0.013
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0014 0.0004 0.0005
Echinococcus multilocularis PHD finger protein rhinoceros 0.0121 0.0421 0.0421
Toxoplasma gondii LsmAD domain-containing protein 0.0154 0.0549 0.6714
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0051 0.0131
Brugia malayi Syntrophin-1 0.0014 0.0004 0.0009
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0005 0.0007
Leishmania major p450 reductase, putative 0.0316 0.1177 0.5149
Loa Loa (eye worm) hypothetical protein 0.009 0.0301 0.0467
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.005 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0125
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Mycobacterium tuberculosis Possible oxygenase 0.0036 0.009 0.0139
Echinococcus multilocularis ceramide kinase 0.0065 0.0203 0.0203
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Schistosoma mansoni alpha glucosidase 0.0071 0.0226 0.035
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0602 0.2286 0.3551
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0316 0.1177 0.5149
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0102 0.0158
Onchocerca volvulus 0.0026 0.0052 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0079
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0048 0.0139 0.0214
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.0014 0.0004 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.005 0.0078
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.005 0.013
Echinococcus granulosus glutamate synthase 0.0013 0.0001 0.0001
Echinococcus granulosus mothers against decapentaplegic 2 0.0022 0.0037 0.0058
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0036 0.009 0.0139
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Leishmania major diacylglycerol kinase-like protein 0.0065 0.0203 0.0887
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0102 0.0443
Schistosoma mansoni lamin 0.0026 0.0052 0.0079
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0498 0.0498
Echinococcus multilocularis lysosomal alpha glucosidase 0.032 0.1191 0.1191
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0485 0.2216
Leishmania major oxidoreductase-like protein 0.0036 0.009 0.0392
Brugia malayi DIX domain containing protein 0.0023 0.004 0.0101
Onchocerca volvulus 0.0014 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0139
Brugia malayi nuclear receptor NHR-67 0.0023 0.004 0.0103
Toxoplasma gondii PHD-finger domain-containing protein 0.0121 0.0421 0.5146
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0014 0.0004 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Brugia malayi conserved hypotetical protein 0.0023 0.004 0.0103
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.005 0.0077
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0333 0.0518
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0036 0.009 0.041
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0005 0.0007
Echinococcus multilocularis multiple pdz domain protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0316 0.1177 0.1829
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0036 0.009 0.0139
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0141 0.0141
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.005 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.005 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0135 0.021
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0094 0.0147
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.004 0.0063
Brugia malayi hypothetical protein 0.0154 0.0549 0.1431
Treponema pallidum hypothetical protein 0.0576 0.2185 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.005 0.005
Brugia malayi flavodoxin family protein 0.0316 0.1177 0.307
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.005 0.005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0079 0.036
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.0001 0.0001
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.004 0.0062
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0014 0.0004 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Toxoplasma gondii flavodoxin domain-containing protein 0.0157 0.0559 0.6838
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0141 0.0365
Trypanosoma cruzi Sphingosine kinase 0.0065 0.0203 0.0887
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0066 0.0206 0.0939
Brugia malayi MH1 domain containing protein 0.005 0.0144 0.0374
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0102 0.0157
Echinococcus multilocularis dnaJ subfamily B 0.086 0.3287 0.3287
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0239 0.2024
Echinococcus multilocularis PRKCA binding protein 0.0014 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0072 0.0229 0.1
Brugia malayi Partitioning defective-6 homolog alpha 0.0014 0.0004 0.0009
Loa Loa (eye worm) flavodoxin family protein 0.0121 0.042 0.0652
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0021 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0039
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Echinococcus multilocularis carbonic anhydrase 0.0223 0.0818 0.0818
Mycobacterium leprae Probable lipase LipE 0.0074 0.0239 0.109
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0018
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.0014 0.0004 0.0006
Brugia malayi Pax transcription factor protein 2 0.1001 0.3833 1
Echinococcus granulosus allatostatin A receptor 0.0026 0.005 0.0078
Echinococcus multilocularis expressed conserved protein 0.0093 0.031 0.031
Brugia malayi gopc protein 0.0014 0.0004 0.0009
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.005 0.0078
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0005 0.0018
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0094 0.6784
Schistosoma mansoni intermediate filament proteins 0.0026 0.0052 0.0079
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0069 0.0219 0.0219
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0048 0.0139 0.0604
Brugia malayi paired box pox-meso protein 0.0019 0.0025 0.0064
Plasmodium falciparum diacylglycerol kinase, putative 0.0065 0.0203 0.0928
Brugia malayi hypothetical protein 0.0221 0.0808 0.2106
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.005 0.013
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0036 0.009 0.0859
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0053 0.0082
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0239 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Trichomonas vaginalis bmru protein, putative 0.0065 0.0203 0.1723
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0223 0.0818 0.127
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0963 0.3685 0.5725
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0125
Onchocerca volvulus 0.0019 0.0025 0.0064
Schistosoma mansoni kinase 0.0047 0.0135 0.0208
Brugia malayi rho guanine nucleotide exchange factor 12 0.0014 0.0004 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0005 0.0011
Toxoplasma gondii diacylglycerol kinase, putative 0.0065 0.0203 0.2482
Schistosoma mansoni biogenic amine receptor 0.0026 0.005 0.0077
Schistosoma mansoni carbonic anhydrase-related 0.0223 0.0818 0.1269
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.005 0.005
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.005 0.0077
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.0301 0.3671
Loa Loa (eye worm) hypothetical protein 0.0223 0.0818 0.127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0206 0.0206
Schistosoma mansoni neuropeptide receptor 0.0026 0.005 0.0077
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.0014 0.0004 0.0009
Echinococcus multilocularis serotonin receptor 0.0026 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Leishmania major cathepsin L-like protease 0.0019 0.0024 0.0102
Onchocerca volvulus 0.0023 0.004 0.0103
Trichomonas vaginalis mercuric reductase, putative 0.0048 0.0139 0.1173
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0239 0.037
Echinococcus granulosus neutral alpha glucosidase AB 0.0071 0.0226 0.0351
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0121 0.042 0.3563
Schistosoma mansoni hypothetical protein 0.0121 0.0421 0.0653
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0141 0.0217
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.025 0.0922 0.1432
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Echinococcus granulosus multiple pdz domain protein 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis tumor protein p63 0.0338 0.1264 0.1264
Echinococcus granulosus dna polymerase kappa 0.0039 0.0102 0.0158
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0051 0.0078
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Entamoeba histolytica type A flavoprotein, putative 0.0121 0.042 0.0651
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0316 0.1177 0.5149
Leishmania major nitrate reductase, putative 0.0036 0.009 0.0392
Brugia malayi nuclear receptor NHR-88 0.0023 0.004 0.0103
Trypanosoma brucei nitrate reductase, putative 0.0036 0.009 0.0392
Echinococcus granulosus g-protein coupled receptor 0.0026 0.005 0.0078
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0021 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0024 0.0061
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0021 0.0089
Loa Loa (eye worm) hypothetical protein 0.0047 0.0135 0.021
Echinococcus multilocularis lysosomal alpha glucosidase 0.032 0.1191 0.1191
Echinococcus granulosus cytochrome b5 reductase 4 0.0036 0.009 0.014
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.005 0.0077
Brugia malayi TAR-binding protein 0.0325 0.1213 0.3163
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.005 0.0078
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0208 0.0542
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0094 0.041
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0182 0.0282
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0141 0.0365
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0024 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0121 0.042 0.3563
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0071 0.0226 0.0351
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0316 0.1177 0.1829
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0066 0.0206 0.0206
Plasmodium vivax ataxin-2 like protein, putative 0.0154 0.0549 0.2511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Echinococcus granulosus jumonji domain containing 1A 0.0039 0.0103 0.0159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0037
Onchocerca volvulus 0.0014 0.0004 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Brugia malayi Dopamine receptor protein 2 0.0026 0.005 0.013
Schistosoma mansoni multiple pdz domain protein 0.0014 0.0004 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0102 0.0264
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis fmrfamide receptor 0.0026 0.005 0.005
Brugia malayi Guanylate kinase family protein 0.0014 0.0004 0.0009
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0014 0.0004 0.0006
Echinococcus granulosus neuropeptide receptor A26 0.0026 0.005 0.0078
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0065 0.0203 0.0203
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Onchocerca volvulus 0.0026 0.005 0.013
Schistosoma mansoni lamin 0.0026 0.0052 0.0079
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0208 0.095
Echinococcus multilocularis carbonic anhydrase 0.0223 0.0818 0.0818
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0061
Brugia malayi neuropeptide F receptor 0.0026 0.005 0.013
Schistosoma mansoni protein phosphatase 2C 0.0039 0.0103 0.0158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.004 0.0063
Plasmodium falciparum phd finger protein, putative 0.0121 0.0421 0.1925
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.004 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.1038 0.1038
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.0203 0.0315
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0048 0.0139 0.0604
Mycobacterium ulcerans monooxygenase 0.0036 0.009 0.0139
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0141 0.0217
Echinococcus multilocularis JmjC domain containing protein 4 0.0039 0.0103 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0141 0.0218
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0443
Echinococcus granulosus neuropeptide s receptor 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Trypanosoma brucei glucosidase, putative 0.0071 0.0226 0.0986
Brugia malayi steroid hormone receptor 0.0049 0.0141 0.0365
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0226 0.035
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Mycobacterium ulcerans hypothetical protein 0.1672 0.6437 1
Plasmodium falciparum transportin 0.0017 0.0017 0.0075
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0036 0.009 0.0392
Brugia malayi protein kinase C-binding protein PICK1 0.0014 0.0004 0.0009
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0214
Onchocerca volvulus 0.0023 0.004 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Brugia malayi Isocitrate dehydrogenase 0.0066 0.0206 0.0535
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.004 0.004
Leishmania major sphingosine kinase A, B, putative 0.0065 0.0203 0.0887
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0043 0.0116 0.0116
Echinococcus multilocularis importin subunit beta 1 0.009 0.0301 0.0301
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Trypanosoma brucei polo-like protein kinase 0.0093 0.0312 0.1364
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0141 0.0365
Plasmodium falciparum ataxin-2 like protein, putative 0.0154 0.0549 0.2511
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0182 0.0282
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0141 0.0365
Toxoplasma gondii isocitrate dehydrogenase 0.0066 0.0206 0.2509
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0079
Brugia malayi G protein-coupled receptor 0.0026 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0036 0.009 0.014
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0141 0.0218
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0089 0.0402
Brugia malayi nuclear receptor RXR 0.0023 0.004 0.0103
Onchocerca volvulus Ceramide kinase 1 homolog 0.0065 0.0203 0.0529
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0006
Schistosoma mansoni paired box protein pax-6 0.0019 0.0025 0.0038
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0017 0.0026
Leishmania major cytochrome-b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni amine GPCR 0.0026 0.005 0.0077
Echinococcus multilocularis disks large 1 0.0014 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0141 0.0365
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0102 0.0157
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0121 0.042 0.1835
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0039 0.0103 0.0446
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0223 0.0818 0.2132
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0102 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0141 0.0365
Onchocerca volvulus 0.0065 0.0203 0.0529
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Echinococcus multilocularis neutral alpha glucosidase AB 0.0071 0.0226 0.0226
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0014 0.0005 0.0007
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0026 0.0053 0.023
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.0139 0.0604
Echinococcus granulosus carbonic anhydrase II 0.0602 0.2286 0.3551
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trypanosoma brucei trypanothione reductase 0.014 0.0493 0.2155
Onchocerca volvulus 0.0298 0.1108 0.2889
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0014 0.0004 0.0006
Mycobacterium ulcerans hypothetical protein 0.0074 0.0239 0.037
Schistosoma mansoni smad 0.0022 0.0037 0.0057
Onchocerca volvulus 0.0049 0.0141 0.0365
Mycobacterium tuberculosis Conserved protein 0.0074 0.0239 0.037
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0017 0.0071
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0014 0.0004 0.0006
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0094 0.041
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.0014 0.0004 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.015 0.0533 0.0828
Brugia malayi ORL1-like opioid receptor 0.0026 0.005 0.013
Schistosoma mansoni ATP-dependent RNA Helicase 0.0014 0.0004 0.0005
Brugia malayi GnHR receptor homolog 0.0026 0.005 0.013
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0185 0.0288
Brugia malayi interleukin-16 0.0014 0.0004 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0007
Echinococcus granulosus disks large 3 0.0014 0.0004 0.0006
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0089
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.005 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus granulosus Partitioning defective 3 protein B 0.0014 0.0004 0.0006
Loa Loa (eye worm) PDZ domain-containing protein 0.0014 0.0004 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0221 0.0808 0.1255
Schistosoma mansoni cell polarity protein 0.0014 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0048 0.0139 0.0632
Echinococcus granulosus lysine specific demethylase 6a 0.0039 0.0103 0.0159
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0316 0.1177 0.5149
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0014 0.0005 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0094 0.0796
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0066 0.0206 0.0319
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0028 0.0028
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0186 0.0673 0.1754
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0021 0.009
Brugia malayi Diacylglycerol kinase protein 2 0.0065 0.0203 0.0529
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.0011
Onchocerca volvulus 0.0014 0.0004 0.0009
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0021 0.0033
Trypanosoma brucei oxidoreductase-protein, putative 0.0036 0.009 0.0392
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Brugia malayi beta-lactamase family protein 0.0074 0.0239 0.0621
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0024 0.0024
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0036 0.009 0.1096
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0005 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.013 0.1098
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0148 0.0524 0.0814
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0115 0.0179
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0021 0.0032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.005 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0141 0.0141
Brugia malayi 'Paired box' domain containing protein 0.0019 0.0025 0.0064
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0239 0.037
Onchocerca volvulus 0.1001 0.3833 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0604
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0013 0.0021
Echinococcus multilocularis protein piccolo 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0026 0.005 0.013
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0047 0.0047
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0021 0.0033
Schistosoma mansoni paired box protein pax-1-related 0.0019 0.0025 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Echinococcus granulosus paired box protein pax 6 0.0019 0.0025 0.0039
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0316 0.1177 0.1828
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Plasmodium falciparum thioredoxin reductase 0.014 0.0493 0.2254
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0316 0.1177 0.1829
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0014 0.0004 0.0006
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0206 0.0897
Echinococcus multilocularis lamin 0.0026 0.0052 0.0052
Loa Loa (eye worm) diacylglycerol kinase 2 0.0065 0.0203 0.0316
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0239 0.1042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.005 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trichomonas vaginalis sphingosine kinase, putative 0.0065 0.0203 0.1723
Schistosoma mansoni maguk P55 subfamily member 35 0.0014 0.0004 0.0005
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0602 0.2286 1
Echinococcus granulosus MAGUK p55 subfamily 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Mycobacterium ulcerans oxidoreductase 0.0036 0.009 0.0139
Leishmania major hypothetical protein, conserved 0.0065 0.0203 0.0887
Brugia malayi nuclear hormone receptor 0.0049 0.0141 0.0365
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0141 0.0365
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0021 0.0089
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0014 0.0004 0.0006
Onchocerca volvulus 0.0014 0.0004 0.0009
Leishmania major hypothetical protein, conserved 0.0017 0.0017 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.005 0.0077
Brugia malayi MH2 domain containing protein 0.005 0.0144 0.0374
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0021 0.0089
Chlamydia trachomatis tail-specific protease 0.0014 0.0004 0.0047
Toxoplasma gondii hypothetical protein 0.0223 0.0818 1
Leishmania major diacylglycerol kinase, putative 0.0065 0.0203 0.0887
Brugia malayi jmjC domain containing protein 0.0039 0.0103 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0141 0.0365
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0141 0.0218
Echinococcus multilocularis somatostatin receptor 0.0026 0.005 0.005
Echinococcus granulosus phd:f box containing protein 0.0039 0.0103 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0141 0.0218
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.005 0.0078
Echinococcus multilocularis jumonji domain containing 1A 0.0039 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Brugia malayi mothers against decapentaplegic homolog 3 0.0022 0.0037 0.0095
Schistosoma mansoni multiple pdz domain protein 0.0014 0.0004 0.0005
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0036 0.009 0.1266
Schistosoma mansoni dishevelled 0.0023 0.004 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0312 0.0484
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0576 0.2185 1
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0135 0.0351
Brugia malayi hypothetical protein 0.0023 0.004 0.0103
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0576 0.2185 0.3394
Leishmania major DNA polymerase eta, putative 0.0039 0.0102 0.0443
Echinococcus multilocularis cysteine protease 0.0019 0.0024 0.0024
Brugia malayi putative neuropeptide receptor 0.0026 0.005 0.013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0354 0.1326 0.6066
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.005 0.0077
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0319 0.1188 0.1844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Loa Loa (eye worm) gopc protein 0.0014 0.0004 0.0006
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0143 0.0221
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0316 0.1177 0.5387
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0005 0.0011
Leishmania major carbonic anhydrase-like protein 0.0602 0.2286 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.005 0.005
Leishmania major cathepsin L-like protease 0.0019 0.0024 0.0102
Schistosoma mansoni patched 1 0.0042 0.0115 0.0178
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Schistosoma mansoni syntenin 0.0014 0.0004 0.0005
Trichomonas vaginalis importin beta-1, putative 0.0073 0.0234 0.1987
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0208 0.2541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Schistosoma mansoni hypothetical protein 0.0069 0.0219 0.034
Leishmania major NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trypanosoma brucei PAB1-binding protein , putative 0.0154 0.0549 0.2401
Loa Loa (eye worm) transcription factor SMAD2 0.073 0.2785 0.4326
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0021 0.009
Trypanosoma brucei unspecified product 0.0027 0.0055 0.0238
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0576 0.2185 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0037 0.0058
Onchocerca volvulus 0.0014 0.0005 0.0011
Echinococcus multilocularis syndecan binding protein (syntenin) 0.0014 0.0004 0.0004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0325 0.1213 0.1884
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0316 0.1177 0.1177
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.005 0.0078
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0005 0.0052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Plasmodium falciparum importin beta, putative 0.009 0.0301 0.1373
Schistosoma mansoni cell polarity protein 0.0014 0.0004 0.0005
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0141 0.0365
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.0203 0.0315
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.005 0.013
Echinococcus multilocularis protein patched 0.0042 0.0115 0.0115
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0005 0.0008
Echinococcus granulosus dnaJ subfamily B 0.086 0.3287 0.5107
Brugia malayi RNA, U transporter 1 0.0256 0.0946 0.2465
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0226 0.0986
Giardia lamblia Hypothetical protein 0.028 0.1038 0.9944
Trypanosoma cruzi diacylglycerol kinase, putative 0.0065 0.0203 0.0887
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0005 0.0018
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.005 0.0078
Echinococcus multilocularis MAGUK p55 subfamily 0.0014 0.0004 0.0004
Echinococcus multilocularis pdz domain containing protein 0.0014 0.0004 0.0004
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0121 0.042 0.3563
Echinococcus multilocularis peregrin 0.0121 0.0421 0.0421
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Brugia malayi hypothetical protein 0.0298 0.1108 0.2889
Brugia malayi FAD binding domain containing protein 0.0316 0.1177 0.307
Schistosoma mansoni tar DNA-binding protein 0.0325 0.1213 0.1883
Schistosoma mansoni hypothetical protein 0.0065 0.0203 0.0315
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0014 0.0004 0.0005
Brugia malayi nuclear receptor NHR-88 0.0049 0.0141 0.0365
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0066 0.0206 0.0206
Entamoeba histolytica type A flavoprotein, putative 0.0121 0.042 0.0651
Echinococcus granulosus serotonin receptor 0.0026 0.005 0.0078
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0021 0.0053
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0007
Onchocerca volvulus 0.0014 0.0004 0.0009
Brugia malayi jmjC domain containing protein 0.0039 0.0103 0.0266
Schistosoma mansoni nuclear receptor 0.0023 0.004 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Onchocerca volvulus 0.0026 0.005 0.013
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.0234 0.1023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0024 0.0197
Loa Loa (eye worm) hypothetical protein 0.0121 0.0421 0.0654
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0094 0.0094
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.041
Echinococcus multilocularis neuropeptide receptor 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Brugia malayi C2 domain containing protein 0.0014 0.0004 0.0009
Schistosoma mansoni jumonji domain containing protein 0.0039 0.0103 0.0158
Echinococcus multilocularis protein lin 7 B 0.0014 0.0004 0.0004
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0036 0.009 0.014
Brugia malayi hypothetical protein 0.0026 0.0051 0.0131
Echinococcus multilocularis lysine specific demethylase 5A 0.0147 0.052 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Toxoplasma gondii PHD-finger domain-containing protein 0.004 0.0105 0.1271
Schistosoma mansoni PDZ domain protein 0.0014 0.0004 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0021 0.0033
Brugia malayi diacylglycerol kinase 0.0065 0.0203 0.0529
Schistosoma mansoni tar DNA-binding protein 0.0325 0.1213 0.1883
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Loa Loa (eye worm) thioredoxin reductase 0.014 0.0493 0.0766
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Leishmania major hypothetical protein, conserved 0.0065 0.0203 0.0887
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni carbonic anhydrase-related 0.0223 0.0818 0.1269
Schistosoma mansoni inositol monophosphatase 0.0037 0.0094 0.0145
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0014 0.0004 0.0004
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0004
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0089 0.0402
Schistosoma mansoni lin-7-like proteins 0.0014 0.0004 0.0005
Loa Loa (eye worm) carbonic anhydrase 3 0.0602 0.2286 0.3551
Onchocerca volvulus 0.0074 0.0239 0.0621
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0102 0.0443
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0024 0.0197
Plasmodium vivax vivapain-2 0.0019 0.0024 0.0106
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0316 0.1177 0.5149
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0148 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Echinococcus multilocularis lamin dm0 0.0026 0.0052 0.0052
Echinococcus granulosus transportin 1 0.0017 0.0017 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.028 0.1038 0.2707
Schistosoma mansoni hypothetical protein 0.0026 0.005 0.0077
Echinococcus granulosus GPCR family 2 0.0148 0.0524 0.0814
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0182 0.0282
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0022 0.0037 0.0095
Echinococcus multilocularis sex peptide receptor 0.0026 0.005 0.005
Echinococcus multilocularis snurportin 1 0.0963 0.3685 0.3685
Trypanosoma cruzi trypanothione reductase, putative 0.014 0.0493 0.2155
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0048 0.0139 0.036
Leishmania major NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Schistosoma mansoni pdz domain containing protein 0.0014 0.0004 0.0005
Brugia malayi MH2 domain containing protein 0.0022 0.0037 0.0095
Leishmania major cytochrome-b5 reductase, putative 0.0036 0.009 0.0392
Schistosoma mansoni neuropeptide receptor 0.0026 0.005 0.0077
Echinococcus multilocularis neuropeptide s receptor 0.0026 0.005 0.005
Entamoeba histolytica hypothetical protein 0.0221 0.0808 0.1254
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0208 0.199
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0036 0.009 0.1096
Onchocerca volvulus 0.0052 0.0152 0.0394
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0021 0.0032
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0014 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0141 0.0218
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0024 0.0106
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0013 0.0013
Toxoplasma gondii exonuclease III APE 0.0018 0.0021 0.025
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0137
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0005 0.0011
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0065 0.0203 0.0315
Echinococcus granulosus snurportin 1 0.0963 0.3685 0.5725
Schistosoma mansoni inositol monophosphatase 0.0037 0.0094 0.0145
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0121 0.042 0.192
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.005 0.0077
Entamoeba histolytica Ran family GTPase 0.0066 0.0208 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Schistosoma mansoni nuclear receptor 0.0023 0.004 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Entamoeba histolytica hypothetical protein 0.0073 0.0234 0.0363
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.0203 0.0315
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0036 0.009 0.041
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0053 0.0447
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Toxoplasma gondii ABC1 family protein 0.0074 0.0239 0.2914
Brugia malayi Latrophilin receptor protein 2 0.0148 0.0524 0.1365
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0135 0.0351
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.004 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0229 0.1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0137
Brugia malayi Ceramide kinase 0.0065 0.0203 0.0529
Mycobacterium ulcerans oxygenase 0.0036 0.009 0.0139
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0312 0.0485
Brugia malayi neuropeptide F receptor 0.0026 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0072 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0141 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0203 0.1723
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0316 0.1177 0.5149
Brugia malayi beta-lactamase family protein 0.0074 0.0239 0.0621
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0065 0.0203 0.0887
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0005 0.0019
Brugia malayi Serotonin receptor 0.0026 0.005 0.013
Onchocerca volvulus 0.0014 0.0004 0.0009
Trypanosoma brucei glycosyl hydrolase-like protein 0.0026 0.0053 0.023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.1038 0.1612
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0467 0.1762 0.4597
Brugia malayi PDZ domain 0.0014 0.0004 0.0009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0048 0.0139 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0005 0.0008
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0047 0.0571
Echinococcus multilocularis lysine specific demethylase 6a 0.0039 0.0103 0.0103
Echinococcus granulosus neuropeptide receptor 0.0026 0.005 0.0078
Onchocerca volvulus 0.0026 0.005 0.013
Plasmodium vivax JmjC domain containing protein 0.0039 0.0103 0.0467
Echinococcus granulosus importin subunit beta 1 0.009 0.0301 0.0467
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0235
Brugia malayi Pre-SET motif family protein 0.0031 0.0072 0.0186
Brugia malayi follicle stimulating hormone receptor 0.0482 0.182 0.4747
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0226 0.1914
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0048 0.0139 0.0632
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0065 0.0203 0.0887
Plasmodium vivax vivapain-2 0.0019 0.0024 0.0106
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0239 0.037
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.0019 0.0024 0.0102
Brugia malayi RNA binding protein 0.0325 0.1213 0.3163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0036 0.009 0.0392
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.004 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0048 0.0139 0.0604
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.0014 0.0004 0.0004
Echinococcus multilocularis transportin 1 0.0017 0.0017 0.0017
Schistosoma mansoni amyloid beta A4 protein related 0.0014 0.0004 0.0005
Brugia malayi nuclear hormone receptor 0.0023 0.004 0.0103
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0014 0.0004 0.0006
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Leishmania major hypothetical protein, conserved 0.0121 0.042 0.1835
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0474 0.1791 0.2781
Brugia malayi CXXC zinc finger family protein 0.006 0.0185 0.0481
Echinococcus granulosus neuropeptide receptor 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trichomonas vaginalis ran, putative 0.0066 0.0208 0.1764
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0014 0.0005 0.0008
Echinococcus granulosus carbonic anhydrase 0.0223 0.0818 0.127
Leishmania major cathepsin L-like protease 0.0072 0.0229 0.1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0312 0.0484
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0005 0.0008
Schistosoma mansoni zinc finger protein 0.0023 0.004 0.0062
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0105 0.0454
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0208 0.0908
Echinococcus granulosus lamin 0.0026 0.0052 0.008
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.009 0.0139
Onchocerca volvulus 0.0019 0.0025 0.0064
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0301 0.1313
Echinococcus granulosus lysine specific demethylase 5A 0.015 0.0533 0.0829
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0005 0.0007
Brugia malayi diacylglycerol kinase 0.0065 0.0203 0.0529
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0141 0.0217
Schistosoma mansoni hypothetical protein 0.0148 0.0524 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0014 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0026 0.005 0.0077
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.0001 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0047 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Brugia malayi hypothetical protein 0.01 0.0337 0.0878
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0014 0.0004 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.0026 0.0053 0.0137
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0005 0.0036
Brugia malayi tailless protein 0.0023 0.004 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi Shank2E 0.0014 0.0004 0.0009
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0576 0.2185 1
Brugia malayi hypothetical protein 0.0023 0.004 0.0103
Plasmodium vivax hypothetical protein, conserved 0.0121 0.042 0.192
Onchocerca volvulus 0.0036 0.009 0.0234
Echinococcus multilocularis MAGUK p55 subfamily 0.0014 0.0004 0.0004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0021 0.0196
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0239 0.109
Schistosoma mansoni carbonic anhydrase-related 0.0223 0.0818 0.1269
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.004 0.0103
Brugia malayi larval opioid receptor 0.0026 0.005 0.013
Brugia malayi Glycosyl hydrolases family 31 protein 0.032 0.1191 0.3105
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0048 0.0139 0.0632
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Brugia malayi Synapse defective protein 1 0.0014 0.0004 0.0009
Trichomonas vaginalis helicase, putative 0.0014 0.0004 0.0027
Echinococcus multilocularis 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0089 0.0136
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Echinococcus granulosus Rho GTPase activating protein 21 0.0014 0.0004 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0141 0.0365
Treponema pallidum flavodoxin 0.0121 0.042 0.192
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0052 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.005 0.0078
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.009 0.0392
Schistosoma mansoni myosin xvIII 0.0026 0.005 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0226 0.1914
Schistosoma mansoni phd/f-box containing protein 0.0039 0.0103 0.0158
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0014 0.0005 0.0007
Brugia malayi PHD-finger family protein 0.0043 0.0118 0.0306
Brugia malayi Ferm domain 0.0014 0.0004 0.0009
Echinococcus granulosus mothers against decapentaplegic 6 0.0022 0.0037 0.0058
Schistosoma mansoni neuropeptide receptor 0.0026 0.005 0.0077
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0115 0.0179
Echinococcus granulosus peregrin 0.0121 0.0421 0.0654
Loa Loa (eye worm) DIX domain-containing protein 0.0023 0.004 0.0061
Loa Loa (eye worm) programmed cell death 8 0.0013 0.0001 0.0001
Loa Loa (eye worm) PX domain-containing protein 0.0014 0.0004 0.0006
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0144 0.0224
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0102 0.0443
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0021 0.0033
Trypanosoma brucei Sphingosine kinase 0.0065 0.0203 0.0887
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0141 0.0141
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.004 0.0105 0.1271
Echinococcus granulosus g protein coupled receptor 0.0026 0.005 0.0078
Brugia malayi PX domain containing protein 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0354 0.1326 0.2059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.005 0.0077
Echinococcus granulosus PHD finger protein rhinoceros 0.0121 0.0421 0.0654
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0065 0.0203 0.0316
Echinococcus granulosus orexin receptor type 2 0.0026 0.005 0.0078
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0094 0.041
Echinococcus granulosus carbonic anhydrase 0.0223 0.0818 0.127
Echinococcus granulosus syndecan binding protein syntenin 0.0014 0.0004 0.0006
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0005 0.0007
Entamoeba histolytica diacylglycerol kinase, putative 0.0065 0.0203 0.0315
Schistosoma mansoni syntrophin 0.0014 0.0004 0.0005
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0005 0.0007
Echinococcus granulosus disks large 1 0.0014 0.0004 0.0006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0102 0.0157
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.005 0.005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0102 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0141 0.0365
Loa Loa (eye worm) hypothetical protein 0.0065 0.0203 0.0316
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.1044 1
Loa Loa (eye worm) hypothetical protein 0.0467 0.1762 0.2738
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Plasmodium vivax transportin, putative 0.0017 0.0017 0.0075
Loa Loa (eye worm) cysteine protease 0.0019 0.0024 0.0037
Brugia malayi RNA recognition motif domain containing protein 0.0325 0.1213 0.3163
Onchocerca volvulus 0.0047 0.0135 0.0351
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Schistosoma mansoni smad1 5 8 and 0.005 0.0144 0.0223
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0021 0.0032
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0065 0.0203 0.0315
Schistosoma mansoni smad1 5 8 and 0.005 0.0144 0.0223
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0103 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0047 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Loa Loa (eye worm) PAR-6 protein 0.0014 0.0004 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0239 0.037
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) hypothetical protein 0.0065 0.0203 0.0316
Loa Loa (eye worm) 9ORF binding protein 1 0.0014 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0226 0.1914
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.004 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0121 0.0421 0.1925
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.0011
Brugia malayi RE15519p 0.0026 0.005 0.013
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0089
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0239 0.2024
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0102 0.0102
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0065 0.0203 0.1723
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0141 0.0218
Brugia malayi hypothetical protein 0.0014 0.0004 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0053 0.0447
Schistosoma mansoni multiple pdz domain protein 0.0014 0.0004 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.005 0.0078
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0024 0.0036
Onchocerca volvulus 0.0026 0.005 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0004 0.0027
Entamoeba histolytica type A flavoprotein, putative 0.0121 0.042 0.0651
Schistosoma mansoni opsin-like receptor 0.0026 0.005 0.0077
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0102 0.0102
Echinococcus multilocularis glutamate synthase 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0019 0.0024 0.0061
Toxoplasma gondii PHD-finger domain-containing protein 0.0121 0.0421 0.5146
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0048 0.0139 0.0604
Brugia malayi Cathepsin L-like precursor 0.0019 0.0024 0.0061
Schistosoma mansoni cytochrome B5 0.0036 0.009 0.0139
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.0011
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0319 0.1188 0.5434
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0021 0.0089
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.0001 0.0001
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0602 0.2286 0.5962
Schistosoma mansoni diflavin oxidoreductase 0.0157 0.0559 0.0868
Echinococcus granulosus translational activator gcn1 0.0017 0.0017 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0159
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0052 0.008
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0021 0.1482
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0023 0.004 0.0103
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0072 0.0111
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0021 0.0089
Trypanosoma brucei unspecified product 0.0027 0.0055 0.0238
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0066 0.0206 0.0897
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0135 0.0209
Loa Loa (eye worm) pax transcription factor protein 2 0.1001 0.3833 0.5955
Schistosoma mansoni dishevelled 0.0023 0.004 0.006
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0014 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.005 0.0078
Entamoeba histolytica hypothetical protein 0.0221 0.0808 0.1254
Trichomonas vaginalis bmru protein, putative 0.0065 0.0203 0.1723
Loa Loa (eye worm) FAD binding domain-containing protein 0.0316 0.1177 0.1829
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0051 0.0079
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.0001 0.0001
Loa Loa (eye worm) TAR-binding protein 0.0325 0.1213 0.1884
Loa Loa (eye worm) X11 protein 0.0014 0.0004 0.0006
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0026 0.0053 0.023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0039 0.0103 0.1248
Brugia malayi PDZ domain containing protein 0.0014 0.0004 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0325 0.1213 0.1883
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0144 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Schistosoma mansoni tar DNA-binding protein 0.0325 0.1213 0.1883
Echinococcus granulosus ceramide kinase 0.0065 0.0203 0.0316
Schistosoma mansoni hypothetical protein 0.0026 0.005 0.0077
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0021 0.0089
Schistosoma mansoni hypothetical protein 0.0041 0.0109 0.0168
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0048 0.0139 0.0604
Giardia lamblia NADH oxidase lateral transfer candidate 0.0048 0.0139 0.1323
Echinococcus granulosus partitioning defective 3 0.0014 0.0004 0.0006
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0203 0.0887
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0094 0.0145
Echinococcus granulosus cathepsin l1 0.0019 0.0024 0.0037
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0089
Brugia malayi PDZ domain containing protein 0.0014 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Schistosoma mansoni microtubule-associated protein tau 0.0691 0.2633 0.4089
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0876 0.7441
Entamoeba histolytica hypothetical protein 0.0221 0.0808 0.1254
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0005 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0053 0.0447
Schistosoma mansoni Smad4 0.0022 0.0037 0.0057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0135 0.021
Echinococcus multilocularis cpg binding protein 0.0064 0.0198 0.0198
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.0203 0.0887
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0014 0.0005 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0141 0.0141
Onchocerca volvulus 0.0026 0.005 0.013
Onchocerca volvulus 0.0019 0.0024 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.005 0.005
Schistosoma mansoni carbonic anhydrase 0.0223 0.0818 0.1269
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0135 0.0209
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0135 0.0615
Echinococcus multilocularis MAGUK p55 subfamily 0.0014 0.0004 0.0004
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0141 0.0218
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0452 0.0701
Schistosoma mansoni smad 0.005 0.0144 0.0223
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.005 0.0078
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0312 0.0485
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0141 0.0218
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0239 0.037
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0316 0.1177 0.5149
Leishmania major cathepsin L-like protease 0.0072 0.0229 0.1
Echinococcus granulosus PRKCA binding protein 0.0014 0.0004 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0229 0.1
Trypanosoma cruzi nitrate reductase, putative 0.0036 0.009 0.0392
Brugia malayi isocitrate dehydrogenase 0.0066 0.0206 0.0535
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0048 0.0139 0.0214
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.004 0.004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0764 0.1188
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0144 0.0144
Mycobacterium ulcerans electron transfer protein FdxB 0.0036 0.009 0.0139
Schistosoma mansoni phosphatidylserine receptor 0.0039 0.0103 0.0158
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Schistosoma mansoni hypothetical protein 0.0221 0.0808 0.1254
Onchocerca volvulus 0.0026 0.005 0.013
Trypanosoma cruzi diacylglycerol kinase, putative 0.0065 0.0203 0.0887
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0137
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0312 0.265
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Leishmania major hypothetical protein, conserved 0.0039 0.0103 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Plasmodium vivax importin-beta 2, putative 0.009 0.0301 0.1373
Echinococcus multilocularis cysteine protease 0.0019 0.0024 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0141 0.0218
Echinococcus multilocularis neuropeptide receptor 0.0026 0.005 0.005
Giardia lamblia Nitric oxide synthase, inducible 0.028 0.1038 0.9944
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0026 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0319 0.1189 0.1847
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1044 0.1621
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0144 0.0224
Plasmodium vivax glutathione reductase, putative 0.014 0.0493 0.2254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1044 0.8865
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Schistosoma mansoni leucine-rich repeat protein 0.0014 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.005 0.0078
Entamoeba histolytica cysteine protease, putative 0.0019 0.0024 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0239 0.109
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Mycobacterium tuberculosis Probable dehydrogenase 0.0319 0.1188 0.1844
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0141 0.0218
Echinococcus granulosus g protein coupled receptor 0.0026 0.005 0.0078
Loa Loa (eye worm) RasGEF domain-containing protein 0.002 0.0029 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Echinococcus multilocularis Diacylglycerol kinase theta 0.0065 0.0203 0.0203
Schistosoma mansoni importin-beta 2 0.0017 0.0017 0.0025
Echinococcus multilocularis orexin receptor type 2 0.0026 0.005 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0141 0.0365
Brugia malayi Dopamine receptor protein 1 0.0026 0.005 0.013
Leishmania major GTP-binding protein, putative 0.0066 0.0208 0.0908
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0141 0.0365
Loa Loa (eye worm) inositol-1 0.0037 0.0094 0.0147
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.005 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0102 0.086
Giardia lamblia Kinase, PLK 0.0093 0.0312 0.2989
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0036 0.009 0.0392
Brugia malayi paired box protein 0.0019 0.0025 0.0064
Echinococcus multilocularis beta 1 syntrophin 0.0014 0.0004 0.0004
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.0014 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Plasmodium falciparum glutathione reductase 0.0048 0.0139 0.0632
Trichomonas vaginalis sucrase-isomaltase, putative 0.0071 0.0226 0.1914
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0021 0.0089
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0014 0.0004 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.005 0.005
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0024 0.0106
Schistosoma mansoni biogenic amine receptor 0.0026 0.005 0.0077
Plasmodium falciparum carbonic anhydrase 0.0223 0.0818 0.3741
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0024 0.0102
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0135 0.0209
Brugia malayi Serotonin receptor 0.0026 0.005 0.013
Brugia malayi FAD binding domain containing protein 0.0195 0.0708 0.1846
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.1672 0.6437 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.004 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.1038 0.1613
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0043 0.0119 0.0541
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.1038 0.1612
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0226 0.1914
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.0141 0.0218
Schistosoma mansoni multiple pdz domain protein 0.0014 0.0004 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0226 0.1914
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.005 0.0077
Onchocerca volvulus 0.0026 0.005 0.013
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.005 0.005
Echinococcus granulosus neurabin 1 0.0014 0.0004 0.0006
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.004 0.0103
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0141 0.0217
Onchocerca volvulus 0.0026 0.005 0.013
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0102 0.0157
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0102 0.0158
Brugia malayi Protein-tyrosine phosphatase 1 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Conserved protein 0.0074 0.0239 0.037
Schistosoma mansoni tar DNA-binding protein 0.0325 0.1213 0.1883
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0399 0.4873
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0048 0.0139 0.0604
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0144 0.0223
Echinococcus multilocularis paired box protein pax 6 0.0019 0.0025 0.0025
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0141 0.0218
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0141 0.0218
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0017 0.0199
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Trypanosoma brucei NADH-dependent fumarate reductase 0.0036 0.009 0.0392
Loa Loa (eye worm) hypothetical protein 0.0065 0.0203 0.0316
Brugia malayi Pre-SET motif family protein 0.021 0.0764 0.1993
Plasmodium vivax diacylglycerol kinase, putative 0.0065 0.0203 0.0928
Brugia malayi AKH receptor 0.0026 0.005 0.013
Echinococcus multilocularis protein dispatched 1 0.0048 0.0138 0.0138
Echinococcus granulosus smad 0.005 0.0144 0.0224
Brugia malayi Importin beta-1 subunit 0.009 0.0301 0.0783
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.005 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0174
Echinococcus granulosus tight junction protein ZO 3 0.0014 0.0004 0.0006
Plasmodium vivax SET domain protein, putative 0.0031 0.0072 0.0326
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0039
Brugia malayi Calcitonin receptor-like protein seb-1 0.0467 0.1762 0.4597
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.005 0.0078
Schistosoma mansoni hypothetical protein 0.0026 0.005 0.0077
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.0236
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.0001 0.0001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0089 0.023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0141 0.0365
Loa Loa (eye worm) hypothetical protein 0.0074 0.0239 0.0371
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0102 0.0443
Schistosoma mansoni smad1 5 8 and 0.005 0.0144 0.0223
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.005 0.005
Echinococcus granulosus sex peptide receptor 0.0026 0.005 0.0078
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.0014 0.0004 0.0004
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0105 0.0454
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0316 0.1177 0.5149
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.005 0.0077
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0223 0.0818 0.2132
Schistosoma mansoni MAGUK homolog 0.0014 0.0004 0.0005
Echinococcus multilocularis multiple pdz domain protein 0.0014 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0028 0.0058 0.0148
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0001 0.0001
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0065 0.0203 0.1723
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0005 0.0007
Echinococcus granulosus paired box protein pax 1 0.0019 0.0025 0.0039
Brugia malayi syntenin 0.0014 0.0004 0.0009
Schistosoma mansoni multiple pdz domain protein 0.0014 0.0004 0.0005
Onchocerca volvulus 0.0026 0.005 0.013
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0021 0.0089
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0024 0.0037
Trypanosoma brucei carbonic anhydrase-like protein 0.0602 0.2286 1
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0006
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0102 0.0264
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.004 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0135 0.0209
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0576 0.2185 0.3394
Trichomonas vaginalis sulfite reductase, putative 0.0316 0.1177 1
Plasmodium falciparum glutathione reductase 0.014 0.0493 0.2254
Loa Loa (eye worm) nuclear factor I 0.0028 0.0058 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.005 0.005
Brugia malayi PHD-finger family protein 0.0121 0.0421 0.1097
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0066 0.0206 0.0897
Brugia malayi MH1 domain containing protein 0.0028 0.0058 0.0148
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0063
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0028 0.0043
Echinococcus multilocularis Rho GTPase activating protein 21 0.0014 0.0004 0.0004
Brugia malayi latrophilin 2 splice variant baaae 0.0319 0.1189 0.3101
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.005 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0226 0.1914
Leishmania major hypothetical protein, conserved 0.0074 0.0239 0.1042
Schistosoma mansoni hypothetical protein 0.0148 0.0524 0.0813
Plasmodium falciparum ataxin-2 like protein, putative 0.0154 0.0549 0.2511
Brugia malayi AF-10 protein 0.004 0.0105 0.0271
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.005 0.013
Leishmania major cathepsin L-like protease 0.0019 0.0024 0.0102
Brugia malayi Patj homolog 0.0014 0.0004 0.0009
Trypanosoma cruzi oxidoreductase-protein, putative 0.0036 0.009 0.0392
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0024 0.0197
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0036 0.009 0.0392
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1044 0.1621
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0223 0.0818 0.2132
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0135 0.0588
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0102 0.0443
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Plasmodium vivax diacylglycerol kinase, putative 0.0065 0.0203 0.0928
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0005 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0135 0.0351
Schistosoma mansoni nuclear hormone receptor 0.0023 0.004 0.0062
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0021 0.009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0141 0.0217
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0159
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Brugia malayi MH1 domain containing protein 0.005 0.0144 0.0374
Echinococcus multilocularis g protein coupled receptor 0.0026 0.005 0.005
Brugia malayi kap beta 3 protein 0.0017 0.0017 0.0042
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.005 0.013
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0005
Brugia malayi MH2 domain containing protein 0.073 0.2785 0.7264
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0141 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0027
Brugia malayi F/Y-rich N-terminus family protein 0.0059 0.018 0.0469
Schistosoma mansoni hypothetical protein 0.0148 0.0524 0.0813
Echinococcus granulosus intermediate filament protein 0.0026 0.0052 0.008
Echinococcus granulosus cytochrome b5 reductase 4 0.0036 0.009 0.014
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0005 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.1038 0.1613
Schistosoma mansoni survival motor neuron protein 0.0052 0.0152 0.0235
Brugia malayi PDZ domain 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0319 0.1189 0.1847
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.005 0.005
Loa Loa (eye worm) vab-3 0.0019 0.0025 0.0039
Echinococcus granulosus fmrfamide receptor 0.0026 0.005 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0115 0.0972
Loa Loa (eye worm) guanylate kinase 0.0014 0.0004 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0239 0.0239
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0498 0.0773
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.004 0.0063
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0069 0.0219 0.0341
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.0001 0.0001
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0039 0.0103 0.1248
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0312 0.1364
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0028 0.0058 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Brugia malayi Thioredoxin reductase 0.014 0.0493 0.1285
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0333 0.0868
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0021 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0024 0.0197
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0051 0.0078
Leishmania major glycosyl hydrolase-like protein 0.0026 0.0053 0.023
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0024 0.0061
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0026 0.0053 0.0137
Schistosoma mansoni protein kinase C alpha binding protein 0.0014 0.0004 0.0005
Schistosoma mansoni sphingoid long chain base kinase 0.1672 0.6437 1
Echinococcus granulosus lamin dm0 0.0026 0.0052 0.008
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0078
Schistosoma mansoni Smad4 0.005 0.0144 0.0223
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0023 0.004 0.0101
Brugia malayi vab-3 gene. 0.0019 0.0025 0.0064
Brugia malayi hypothetical protein 0.0254 0.0936 0.2441
Echinococcus granulosus Diacylglycerol kinase theta 0.0065 0.0203 0.0316
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0141 0.0217
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0223 0.0818 0.127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0023 0.004 0.0062
Brugia malayi CHE-14 protein 0.0042 0.0115 0.0298
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0004 0.0027
Brugia malayi MH2 domain containing protein 0.005 0.0144 0.0374
Loa Loa (eye worm) FAD binding domain-containing protein 0.0195 0.0708 0.11
Loa Loa (eye worm) hypothetical protein 0.0186 0.0673 0.1046
Loa Loa (eye worm) hypothetical protein 0.005 0.0143 0.0222
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0221 0.0808 0.0808
Schistosoma mansoni amine GPCR 0.0026 0.005 0.0077
Brugia malayi hypothetical protein 0.0026 0.005 0.013
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0301 0.1313
Loa Loa (eye worm) syntrophin-1 0.0014 0.0004 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0141 0.0218
Loa Loa (eye worm) hypothetical protein 0.0254 0.0936 0.1454
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0014 0.0004 0.0004
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0208 0.0208
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0094 0.041
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0048 0.0139 0.0632
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0036 0.009 0.0139
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0115 0.0179
Echinococcus multilocularis translational activator gcn1 0.0017 0.0017 0.0017

Activities

Activity type Activity value Assay description Source Reference
Cytotoxicity (functional) 0 In vitro cytotoxic effect in 1 of 6 human tumor xenografts, LXFS ChEMBL. 8691459
IC50 (binding) > 1000 uM Inhibition of Cell division cycle 2 (cdc2) kinase ChEMBL. 8691459
IC50 (binding) > 1000 uM Inhibition of Cell division cycle 25 (Cdc25) phosphatase ChEMBL. 8691459
IC50 (binding) > 1000 uM Inhibition of Cell division cycle 2 (cdc2) kinase ChEMBL. 8691459
IC50 (binding) > 1000 uM Inhibition of Cell division cycle 25 (Cdc25) phosphatase ChEMBL. 8691459
Mean IC70 (functional) > 10 ug ml-1 In vitro cytotoxicity in nonsmall cell lung carcinoma cell line LXFL 529 and small cell lung carcinoma cell line LXFS 538 human tumor xenografts. ChEMBL. 8691459

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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