Detailed information for compound 175073

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 732.856 | Formula: C42H52O11
  • H donors: 2 H acceptors: 2 LogP: 6.82 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(ccc1OC(C(c1ccc(c(c1)OC)OC)O)C)[C@H]1O[C@@H]([C@@H]([C@H]1C)C)c1ccc(c(c1)OC)OC(C(c1ccc(c(c1)OC)OC)O)C
  • InChi: 1S/C42H52O11/c1-23-24(2)42(30-14-18-34(38(22-30)50-10)52-26(4)40(44)28-12-16-32(46-6)36(20-28)48-8)53-41(23)29-13-17-33(37(21-29)49-9)51-25(3)39(43)27-11-15-31(45-5)35(19-27)47-7/h11-26,39-44H,1-10H3/t23-,24-,25?,26?,39?,40?,41+,42+/m1/s1
  • InChiKey: ZGXXNVOBEIRACL-JAWLWFRMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens sterol O-acyltransferase 1 Starlite/ChEMBL References
Homo sapiens sterol O-acyltransferase 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Echinococcus multilocularis sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Schistosoma mansoni sterol O-acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Schistosoma japonicum ko:K00637 sterol O-acyltransferase [EC2.3.1.26], putative Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme sterol O-acyltransferase 2 522 aa 531 aa 25.2 %
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha sterol O-acyltransferase 1 492 aa 413 aa 25.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1473 0.5505 0.7964
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis orexin receptor type 2 0.0366 0.1325 0.1322
Plasmodium vivax vivapain-3 0.0032 0.0063 0.0332
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0102 0.0141
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi G-protein coupled receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0052 0.0138 0.0134
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0016 0.0004 0.0006
Leishmania major phosphatidylinositol 3-kinase, putative 0.0181 0.0628 0.0909
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0174 0.1002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0126 0.042 0.0583
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0016 0.0005 0.0007
Echinococcus multilocularis neuropeptides capa receptor 0.0366 0.1325 0.1322
Plasmodium falciparum DNA gyrase subunit B 0.0139 0.0467 0.2772
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.002 0.0018 0.0027
Echinococcus granulosus peregrin 0.0057 0.016 0.0225
Schistosoma mansoni heat shock protein 0.0162 0.0555 0.0803
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0025 0.0188
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0162 0.0555 0.0797
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Echinococcus granulosus cathepsin b 0.017 0.0587 0.0843
Loa Loa (eye worm) phosphatidylinositol 3 0.0147 0.0497 0.0713
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0057 0.0159 0.0224
Mycobacterium ulcerans polyketide synthase Pks13 0.003 0.0058 0.0481
Trypanosoma cruzi target of rapamycin kinase 3 0.1473 0.5505 0.7964
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0366 0.1325 0.1913
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0363 0.1313 0.1894
Loa Loa (eye worm) hypothetical protein 0.0057 0.0159 0.0224
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0366 0.1325 0.1918
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0083 0.0159
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Echinococcus granulosus tar DNA binding protein 0.007 0.0206 0.0292
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Giardia lamblia Pms1-like protein 0.0139 0.0467 0.0579
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Mycobacterium tuberculosis Conserved protein 0.0139 0.0467 0.411
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Trichomonas vaginalis endoplasmin, putative 0.0301 0.1078 0.1538
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0038 0.0088 0.0122
Loa Loa (eye worm) hypothetical protein 0.0135 0.0452 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Echinococcus granulosus mitogen activated protein kinase 14 0.0215 0.0755 0.1087
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0004 0.0004
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0021 0.0025 0.0182
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0021 0.0025 0.0188
Onchocerca volvulus 0.0061 0.0174 0.1287
Onchocerca volvulus 0.0135 0.0452 0.3389
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Plasmodium vivax heat shock protein 90, putative 0.0162 0.0555 0.3317
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0163 0.0559 0.0555
Brugia malayi follicle stimulating hormone receptor 0.0366 0.1325 0.1913
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0452 0.0647
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0432 0.0619
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Echinococcus granulosus fmrfamide receptor 0.0366 0.1325 0.1913
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0016 0.0004 0.0006
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0176 0.0608 0.0855
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0148 0.0214
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0245 0.087 0.1259
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0144 0.0139
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0139 0.0467 0.4106
Schistosoma mansoni hypothetical protein 0.0162 0.0554 0.0801
Schistosoma mansoni aryl hydrocarbon receptor 0.0176 0.0609 0.0881
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0093
Brugia malayi larval opioid receptor 0.0366 0.1325 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Plasmodium falciparum heat shock protein 90 0.0453 0.1655 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0251 0.0892 0.1267
Loa Loa (eye worm) serotonin transporter b 0.0165 0.0565 0.0812
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0016 0.0004 0.0006
Onchocerca volvulus 0.0037 0.0083 0.0605
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0181 0.0628 0.0909
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0211 0.074 0.1065
Onchocerca volvulus 0.0057 0.0159 0.1177
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Mycobacterium tuberculosis Probable thioesterase TesA 0.0017 0.0007 0.0033
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0052 0.0138 0.0134
Brugia malayi TAR-binding protein 0.007 0.0206 0.0292
Toxoplasma gondii heat shock protein HSP90 0.0453 0.1655 0.3216
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Brugia malayi putative neuropeptide receptor 0.0366 0.1325 0.1913
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.036 0.1304 0.1882
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0052 0.0138 0.0194
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0119 0.0173
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0504 0.1848 0.3591
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0148 0.0285
Brugia malayi Dopamine receptor protein 2 0.0366 0.1325 0.1913
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0139 0.0467 0.0676
Onchocerca volvulus Matrilysin homolog 0.0114 0.0374 0.28
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0054 0.0149 0.0215
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0119 0.0876
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Onchocerca volvulus Matrilysin homolog 0.0253 0.0898 0.6764
Mycobacterium ulcerans two component regulator - sensor kinase 0.0139 0.0467 0.411
Echinococcus granulosus cathepsin L cysteine proteinase 0.0057 0.0159 0.0224
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0287 0.1029 0.1489
Echinococcus granulosus heat shock protein 0.0453 0.1655 0.239
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Treponema pallidum sodium- and chloride- dependent transporter 0.0165 0.0565 0.43
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0139 0.0467 0.411
Echinococcus granulosus neuropeptide s receptor 0.0366 0.1325 0.1913
Leishmania major hypothetical protein, conserved 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0366 0.1324 0.2573
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Echinococcus granulosus potassium voltage gated channel protein 0.0062 0.0177 0.0249
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0126 0.042 0.3692
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0591 0.2176 0.3144
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0037 0.0082 0.0113
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Loa Loa (eye worm) hypothetical protein 0.0267 0.0953 0.1374
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Brugia malayi MH2 domain containing protein 0.0205 0.0717 0.1032
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0061 0.0174 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0507 0.1859 0.267
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0494 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0494 0.069
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0016 0.0004 0.0006
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Onchocerca volvulus 0.0366 0.1325 1
Trichomonas vaginalis conserved hypothetical protein 0.0228 0.0804 0.114
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Plasmodium vivax endoplasmin, putative 0.0453 0.1655 1
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0139 0.0467 0.411
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0046 0.0117 0.0142
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0061 0.0174 0.017
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0139 0.0467 0.0905
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0119 0.0167
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Onchocerca volvulus 0.0126 0.042 0.315
Loa Loa (eye worm) norepinephrine transporter 0.0165 0.0565 0.0812
Schistosoma mansoni endoplasmin 0.0453 0.1655 0.2394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0143 0.0482 0.0934
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.037 0.1341 0.1935
Echinococcus granulosus serotonin receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.017 0.0587 0.0843
Loa Loa (eye worm) hypothetical protein 0.0225 0.0795 0.1144
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0546 0.2004 0.2001
Echinococcus multilocularis neuropeptide Y receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.002 0.0018 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0147 0.0497 0.0713
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0052 0.0138 0.0194
Schistosoma mansoni sodium/chloride dependent transporter 0.0165 0.0565 0.0818
Giardia lamblia Phosphatidylinositol 4-kinase 0.0147 0.0497 0.0623
Onchocerca volvulus 0.0061 0.0174 0.1287
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0139 0.0467 0.2772
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0126 0.042 0.3692
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0882 0.3272 0.4734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0181 0.0628 0.0903
Loa Loa (eye worm) phosphatidylinositol 3 0.0135 0.0452 0.0647
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0162 0.0554 0.0802
Brugia malayi putative neuropeptide receptor NPR1 0.0366 0.1325 0.1913
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Entamoeba histolytica cysteine proteinase 1, putative 0.0032 0.0063 0.0066
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.0219
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0063 0.018 0.0261
Schistosoma mansoni adenoreceptor 0.0366 0.1325 0.1918
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Trichomonas vaginalis adenylate cyclase, putative 0.0046 0.0117 0.0142
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0039 0.0091 0.0777
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0083 0.0438
Trichomonas vaginalis PIKK family atypical protein kinase 0.1244 0.4638 0.6702
Echinococcus multilocularis GPCR, family 2 0.0042 0.0102 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Loa Loa (eye worm) cathepsin B 0.0063 0.018 0.0255
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0027 0.0022
Entamoeba histolytica heat shock protein 90, putative 0.0453 0.1655 0.2374
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.002 0.002 0.014
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0034 0.0071 0.0097
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0062 0.0177 0.0249
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0007
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0419 0.0606
Brugia malayi PHD-finger family protein 0.0055 0.0151 0.0213
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0061 0.0173 0.0169
Loa Loa (eye worm) hypothetical protein 0.0037 0.0085 0.0117
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Echinococcus granulosus g-protein coupled receptor 0.0366 0.1325 0.1913
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0139 0.0467 0.411
Plasmodium falciparum cysteine proteinase falcipain 3 0.0057 0.0159 0.0898
Trypanosoma brucei heat shock protein 84, putative 0.0162 0.0555 0.0803
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.063 0.2322 0.3355
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0089 0.017
Brugia malayi jmjC domain containing protein 0.0126 0.0419 0.06
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0647
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0135 0.0452 0.0647
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Echinococcus multilocularis mitogen activated protein kinase 11 0.0215 0.0755 0.0751
Echinococcus granulosus hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Loa Loa (eye worm) G-protein coupled receptor 0.0366 0.1325 0.1913
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Toxoplasma gondii cathepsin CPL 0.0057 0.0159 0.0306
Echinococcus granulosus neuropeptide Y receptor 0.0366 0.1325 0.1913
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0083 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Brugia malayi Tachykinin-like peptides receptor 99D 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.017 0.0584 0.0839
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0177 0.0255
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0119 0.0115
Brugia malayi Dopamine receptor 0.0366 0.1325 0.1913
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0428 0.0594
Brugia malayi SH2 domain containing protein 0.017 0.0584 0.0839
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0144 0.0202
Onchocerca volvulus 0.0057 0.0159 0.1177
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0366 0.1325 0.1918
Plasmodium falciparum acyl-CoA synthetase 0.0094 0.03 0.1753
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0061 0.0172 0.0168
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0056 0.0155 0.0218
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1473 0.5505 0.7964
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0181 0.0628 0.1219
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0362 0.1312 0.1877
Echinococcus multilocularis lysine specific demethylase 5A 0.0124 0.0412 0.0407
Schistosoma mansoni zinc finger protein 0.0052 0.0138 0.02
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0206 0.0292
Leishmania major hypothetical protein, conserved 0.0033 0.0068 0.0099
Echinococcus granulosus 7TM GPCR rhodopsin 0.0366 0.1325 0.1913
Plasmodium vivax hypothetical protein, conserved 0.0135 0.0452 0.2689
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0052 0.0138 0.02
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0139 0.0467 0.3311
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0034 0.0071 0.0067
Echinococcus granulosus phd:f box containing protein 0.0033 0.0068 0.0093
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0083 0.0709
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0135 0.0452 0.0653
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0139 0.0467 0.0676
Echinococcus granulosus neuropeptide FF receptor 2 0.0366 0.1325 0.1913
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0245 0.087 0.1259
Onchocerca volvulus 0.0366 0.1325 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis neuropeptides capa receptor 0.0366 0.1325 0.1322
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0006 0.0009
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0362 0.1312 0.1898
Plasmodium vivax heat shock protein 86, putative 0.0453 0.1655 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0068 0.013
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0164 0.0159
Mycobacterium leprae PROBABLE HYDROLASE 0.0139 0.0468 0.411
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0165 0.0565 0.0812
Leishmania major protein kinase, putative 0.0052 0.0139 0.0202
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Loa Loa (eye worm) heat shock protein 90 0.0453 0.1655 0.239
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0362 0.1312 0.1898
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0135 0.0452 0.0653
Brugia malayi RNA binding protein 0.007 0.0206 0.0292
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0139 0.0467 0.411
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.005 0.0232
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0095 0.0301 0.0435
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0159 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0126 0.042 0.3692
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0139 0.0467 0.0651
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0139 0.0468 0.0671
Brugia malayi intermediate filament protein 0.0025 0.0039 0.0051
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0094 0.03 0.2624
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus granulosus geminin 0.0476 0.1743 0.2516
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0068 0.0346
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0163 0.0559 0.1084
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0366 0.1325 0.1322
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Loa Loa (eye worm) TYRA-2 protein 0.0366 0.1325 0.1913
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0009 0.0013
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trypanosoma brucei cysteine peptidase C (CPC) 0.0063 0.018 0.0261
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Loa Loa (eye worm) RNA binding protein 0.007 0.0206 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0016 0.0004 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0083 0.0159
Loa Loa (eye worm) hypothetical protein 0.0069 0.0204 0.0289
Brugia malayi GnHR receptor homolog 0.0366 0.1325 0.1913
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0004 0.0006
Mycobacterium ulcerans polyketide synthase 0.002 0.002 0.0146
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0006 0.0002
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.002 0.0018 0.0032
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0159 0.0204
Brugia malayi RE15519p 0.0366 0.1325 0.1913
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0144 0.0202
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0184 0.0638 0.0899
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0184 0.064 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0028 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Treponema pallidum heat shock protein 90 0.0315 0.1131 1
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0116 0.0167
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0139 0.0467 0.411
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0445 0.1624 0.1621
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0139 0.0467 0.0905
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0414 0.1508 0.2176
Loa Loa (eye worm) PDE1B protein 0.0445 0.1624 0.2345
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0028 0.005 0.0072
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0018 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.036 0.1304 0.1882
Onchocerca volvulus 0.0072 0.0216 0.161
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi hypothetical protein 0.0042 0.01 0.0139
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0366 0.1325 0.1918
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1312 0.1893
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis neuropeptide receptor 0.0366 0.1325 0.1322
Schistosoma mansoni bromodomain containing protein 0.0062 0.0177 0.0256
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0093
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0034 0.0071 0.0362
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0184 0.064 0.3833
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.002 0.002 0.0146
Echinococcus granulosus allatostatin A receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0159 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0094 0.011
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Mycobacterium ulcerans hydrolase 0.0139 0.0468 0.4113
Giardia lamblia DNA repair protein RAD52 0.0256 0.0909 0.1225
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0052 0.0138 0.0134
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0199 0.0693 0.0909
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trypanosoma brucei glycerol uptake protein, putative 0.0052 0.0138 0.02
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.1127 0.4197 0.6069
Echinococcus granulosus expressed conserved protein 0.0041 0.0097 0.0135
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0139 0.0467 0.067
Echinococcus granulosus cathepsin L 0.0032 0.0063 0.0086
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0046 0.0117 0.0142
Mycobacterium ulcerans heat shock protein 90 0.0315 0.1131 1
Echinococcus granulosus neuropeptide receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Schistosoma mansoni myosin xvIII 0.0366 0.1325 0.1918
Echinococcus granulosus orexin receptor type 2 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.013 0.0434 0.0622
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0083 0.0709
Toxoplasma gondii PHD-finger domain-containing protein 0.0055 0.0151 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0139 0.0467 0.411
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1913
Brugia malayi Hsp90 protein 0.0162 0.0555 0.0797
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0075 0.0103
Echinococcus multilocularis neuropeptide s receptor 0.0366 0.1325 0.1322
Loa Loa (eye worm) hypothetical protein 0.1127 0.4197 0.6069
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0034 0.0071 0.0067
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0016 0.0004 0.0006
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0006 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1322
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0052 0.0138 0.02
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) phosphatidylinositol 3 0.014 0.0472 0.0677
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0184 0.064 0.5642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Echinococcus granulosus biogenic amine 5HT receptor 0.0366 0.1325 0.1913
Echinococcus granulosus cathepsin l cysteine peptidase 0.0057 0.0159 0.0224
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0135 0.0452 0.0653
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0184 0.0638 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0159 0.0204
Brugia malayi hypoxia-induced factor 1 0.0545 0.2003 0.2893
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1846 0.6912 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.042 0.3688
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0083 0.0115
Giardia lamblia Heat shock protein HSP 90-alpha 0.0453 0.1655 0.2315
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Leishmania major eukaryotic translation initiation factor-like 0.002 0.0018 0.0027
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0139 0.0467 0.411
Plasmodium vivax unspecified product 0.0032 0.0063 0.0332
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0052 0.0138 0.0194
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0135 0.0452 0.0875
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0009 0.0006
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Loa Loa (eye worm) hypothetical protein 0.0055 0.0152 0.0213
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0048 0.0123 0.0172
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0804 0.114
Loa Loa (eye worm) hypothetical protein 0.0046 0.0117 0.0163
Leishmania major oxidoreductase-like protein 0.0016 0.0004 0.0005
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0402 0.1461 0.2839
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0315 0.1131 1
Leishmania major heat shock protein, putative 0.0162 0.0555 0.0803
Trypanosoma cruzi cysteine protease, putative 0.0032 0.0063 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0006 0.0003
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0016 0.0004 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1846 0.6912 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0135 0.0452 0.0628
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.002 0.0146
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0039 0.0051
Toxoplasma gondii DNA topoisomerase 2, putative 0.0139 0.0467 0.0905
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0139 0.0467 0.3311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0052 0.0138 0.0134
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0063 0.018 0.0261
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus granulosus single minded 2 0.0134 0.045 0.0645
Mycobacterium ulcerans hypothetical protein 0.0126 0.042 0.3692
Mycobacterium ulcerans thioesterase 0.0017 0.0007 0.0033
Brugia malayi Serotonin receptor 0.0366 0.1325 0.1913
Onchocerca volvulus 0.0047 0.0119 0.0876
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1322
Trichomonas vaginalis receptor histidine kinase, putative 0.0139 0.0467 0.0651
Loa Loa (eye worm) hypothetical protein 0.0042 0.0102 0.0141
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0366 0.1325 0.1322
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0135 0.0452 0.2689
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0148 0.0214
Schistosoma mansoni hypothetical protein 0.0135 0.0452 0.0653
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Echinococcus granulosus neuropeptide receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0068 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.03 0.2624
Trypanosoma brucei developmentally regulated phosphoprotein 0.1127 0.4197 0.6072
Schistosoma mansoni intermediate filament proteins 0.0025 0.0039 0.0057
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0119 0.0167
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0016 0.0004 0.0006
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0061 0.0174 0.0245
Schistosoma mansoni jumonji domain containing protein 0.02 0.0701 0.1013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Plasmodium falciparum phosphodiesterase gamma, putative 0.0034 0.0071 0.0362
Leishmania major phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0021
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0366 0.1325 0.1913
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.002 0.002 0.014
Trichomonas vaginalis porcupine, putative 0.0052 0.0138 0.0174
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0135 0.0452 0.0653
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0238 0.084 0.0836
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0135 0.0452 0.0628
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Loa Loa (eye worm) neuropeptide F receptor 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Probable two component sensor kinase 0.0139 0.0467 0.411
Brugia malayi hypothetical protein 0.0061 0.0174 0.0245
Echinococcus multilocularis neuropeptide Y receptor 0.0366 0.1325 0.1322
Brugia malayi AF-10 protein 0.0018 0.0011 0.001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi heat shock protein 90, putative 0.0291 0.1044 0.151
Brugia malayi Serotonin receptor 0.0366 0.1325 0.1913
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0068 0.0099
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0295 0.1057 0.1507
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0016 0.0004 0.0006
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma cruzi Heat shock protein 83, putative 0.0453 0.1655 0.2394
Leishmania major cysteine peptidase A (CPA) 0.0057 0.0159 0.023
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0068 0.0093
Leishmania major phosphatidylinositol kinase, putative 0.0135 0.0452 0.0653
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0027 0.0039
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1913
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0148 0.0214
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0139 0.0467 0.4106
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0068 0.0099
Loa Loa (eye worm) fatty acid synthase 0.002 0.0019 0.0021
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0184 0.0638 0.0917
Loa Loa (eye worm) hypothetical protein 0.011 0.0357 0.0511
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Mycobacterium leprae conserved hypothetical protein 0.0135 0.0452 0.3968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0095 0.0301 0.0336
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0091 0.0126
Echinococcus multilocularis serotonin receptor 0.0366 0.1325 0.1322
Schistosoma mansoni neuropeptide F-like receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0447
Toxoplasma gondii cathepsin B 0.0063 0.018 0.0347
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0184 0.064 0.9996
Brugia malayi neuropeptide F receptor 0.0366 0.1325 0.1913
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0162 0.0554 0.4164
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0114 0.0374 0.0541
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0245 0.087 0.1235
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0016 0.0004 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0063 0.0092
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0366 0.1325 0.1913
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Loa Loa (eye worm) fibroinase 0.0057 0.0159 0.0224
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0456 0.1666 0.1662
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0016 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1204 0.4489 0.6485
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Plasmodium vivax DNA topoisomerase II, putative 0.0139 0.0467 0.2784
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0034 0.0071 0.0097
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0016 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Loa Loa (eye worm) PHD-finger family protein 0.0055 0.0151 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.1578 0.5902 0.8535
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0018 0.0011 0.0019
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Onchocerca volvulus 0.0366 0.1325 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0147 0.0497 0.0719
Echinococcus granulosus biogenic amine 5HT receptor 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0016 0.0004 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Onchocerca volvulus 0.0162 0.0554 0.416
Loa Loa (eye worm) prolyl oligopeptidase 0.0162 0.0554 0.0796
Loa Loa (eye worm) phosphatidylinositol kinase 0.0135 0.0452 0.0647
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0034 0.0071 0.0067
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi kinase, mitochondrial precursor 0.1127 0.4197 0.6069
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Loa Loa (eye worm) hypothetical protein 0.0039 0.0091 0.0126
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Entamoeba histolytica vacuolar protein sorting 26 0.0052 0.0138 0.0174
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0316 0.1136 0.1638
Schistosoma mansoni hypothetical protein 0.002 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0144 0.0202
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0445 0.1624 0.2345
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Brugia malayi G protein-coupled receptor 0.0366 0.1325 0.1913
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0083 0.0115
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0083 0.0703
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Brugia malayi Cathepsin L-like cysteine proteinase 0.004 0.0094 0.013
Mycobacterium leprae Probable polyketide synthase Pks1 0.0021 0.0025 0.0182
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0362
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0159 0.1177
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0295 0.1057 0.1507
Onchocerca volvulus 0.013 0.0434 0.3258
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Toxoplasma gondii hypothetical protein 0.0052 0.0138 0.0266
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Plasmodium falciparum cysteine proteinase falcipain 1 0.0032 0.0063 0.0316
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0139 0.0467 0.0463
Trypanosoma brucei DNA topoisomerase ii 0.0139 0.0467 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0034 0.0071 0.0097
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0076 0.0104
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0139 0.0467 0.3507
Leishmania major hypothetical protein, conserved 0.0034 0.0071 0.0103
Schistosoma mansoni cytochrome P450 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0139 0.0467 0.067
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0037 0.0083 0.0115
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0225 0.0795 0.1144
Entamoeba histolytica heat shock protein 90, putative 0.0453 0.1655 0.2374
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0165 0.0565 0.0818
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0267 0.0953 0.095
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0009
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0091 0.0285 0.0407
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) solute carrier family 6 member 4 0.0165 0.0565 0.0812
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0245 0.087 0.1253
Brugia malayi FAT domain containing protein 0.0267 0.0953 0.1374
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0016 0.0004 0.0006
Echinococcus multilocularis sodium and chloride dependent glycine 0.0225 0.0795 0.0791
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0139 0.0467 0.411
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0144 0.0208
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0377
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0452 0.0647
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0139 0.0467 0.067
Echinococcus granulosus cathepsin l1 0.0057 0.0159 0.0224
Brugia malayi PHD-finger family protein 0.002 0.0019 0.0021
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0366 0.1325 0.1913
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.002 0.0018 0.0027
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0083 0.0703
Trichomonas vaginalis hypothetical protein 0.0184 0.064 0.0902
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0039 0.0091 0.0777
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0052 0.0138 0.0266
Onchocerca volvulus Glucosylceramidase homolog 0.0138 0.0466 0.3499
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Trypanosoma cruzi cruzipain precursor, putative 0.0057 0.0159 0.023
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni cathepsin F (C01 family) 0.004 0.0094 0.0136
Entamoeba histolytica hypothetical protein 0.0362 0.1312 0.1877
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Loa Loa (eye worm) hypothetical protein 0.0037 0.0083 0.0115
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.037 0.1341 0.1919
Echinococcus multilocularis fmrfamide receptor 0.0366 0.1325 0.1322
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) matrixin family protein 0.0275 0.0984 0.1418
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0068 0.0099
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Echinococcus granulosus neuropeptide Y receptor 0.0366 0.1325 0.1913
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) translation initiation factor 4E 0.002 0.0018 0.002
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0139 0.0467 0.0676
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0366 0.1325 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.017 0.0587 0.0849
Onchocerca volvulus 0.0366 0.1325 1
Loa Loa (eye worm) heat shock protein 75 0.0162 0.0555 0.0797
Loa Loa (eye worm) phosphatidylinositol 3 0.0111 0.0362 0.0518
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0061 0.0174 0.0169
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0159 0.0155
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Schistosoma mansoni growth hormone secretagogue receptor 0.0366 0.1325 0.1918
Schistosoma mansoni polycystin 1-related 0.0061 0.0172 0.0249
Echinococcus multilocularis heat shock protein 90 0.0315 0.1131 0.1128
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0061 0.0172 0.0243
Brugia malayi Endoplasmin precursor 0.0453 0.1655 0.239
Loa Loa (eye worm) MBCTL1 0.0053 0.0144 0.0202
Loa Loa (eye worm) hypothetical protein 0.0228 0.0804 0.1158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0063 0.0092
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0006 0.0003
Loa Loa (eye worm) phosphatidylinositol 3 0.0392 0.1424 0.2056
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0245 0.087 0.1235
Loa Loa (eye worm) G-protein coupled receptor 0.0366 0.1325 0.1913
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Leishmania major phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0009 0.0007
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0245 0.087 0.1235
Echinococcus multilocularis heat shock protein 0.0453 0.1655 0.1651
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0174 0.0251
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0016 0.0004 0.0006
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0083 0.0079
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0016 0.0004 0.0006
Echinococcus granulosus serine protein kinase ATM 0.0362 0.1312 0.1893
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0039 0.0091 0.0777
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0016 0.0005 0.0014
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) matrixin family protein 0.0253 0.0898 0.1293
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0046 0.0117 0.0163
Entamoeba histolytica DNA topoisomerase II, putative 0.0139 0.0467 0.0651
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0034 0.0071 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0094 0.03 0.2698
Mycobacterium ulcerans DNA gyrase subunit B 0.0139 0.0467 0.411
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0056 0.0155 0.1341
Plasmodium falciparum DNA topoisomerase 2 0.0139 0.0467 0.2772
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0231 0.0816 0.1088
Echinococcus granulosus lysine specific demethylase 5A 0.0126 0.0419 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0452 0.0628
Brugia malayi jmjC domain containing protein 0.0238 0.084 0.121
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0315 0.1131 0.1632
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0091 0.0777
Echinococcus multilocularis zinc finger protein 0.0019 0.0016 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1846 0.6912 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.0213
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis fmrfamide receptor 0.0366 0.1325 0.1322
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0362 0.1312 0.1898
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0366 0.1325 0.1918
Trypanosoma brucei heat shock protein 90, putative 0.0453 0.1655 0.2394
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.063 0.2322 0.3355
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.037 0.1341 0.194
Onchocerca volvulus 0.004 0.0094 0.0683
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Plasmodium vivax DNA gyrase subunit B, putative 0.0139 0.0467 0.2784
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0139 0.0467 0.411
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0163 0.0559 0.0809
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Schistosoma mansoni transcription factor LCR-F1 0.0061 0.0172 0.0249
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0068 0.0099
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0225 0.0795 0.0791
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0061 0.0174 0.0169
Onchocerca volvulus 0.0042 0.0104 0.076
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0139 0.0467 0.0651
Brugia malayi G-protein coupled receptor 0.0366 0.1325 0.1913
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0061 0.0174 0.0245
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0147 0.0497 0.0713
Onchocerca volvulus 0.0366 0.1325 1
Entamoeba histolytica hypothetical protein 0.0052 0.0138 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Echinococcus granulosus neuropeptides capa receptor 0.0366 0.1325 0.1913
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Brugia malayi G protein-coupled receptor F59B2.13 0.0366 0.1325 0.1913
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0054 0.0149 0.0215
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0148 0.0144
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0017 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0139 0.0468 0.0671
Plasmodium vivax vivapain-2 0.0057 0.0159 0.0913
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Mycobacterium ulcerans putative regulatory protein 0.013 0.0436 0.3835
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0028 0.005 0.0066
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0021 0.0025 0.0188
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.063 0.2322 0.3359
Loa Loa (eye worm) jmjC domain-containing protein 0.0114 0.0372 0.0533
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0016 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Plasmodium vivax JmjC domain containing protein 0.0033 0.0068 0.0362
Leishmania major phosphatidylinositol 3-kinase, putative 0.063 0.2322 0.3359
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Echinococcus granulosus neuropeptides capa receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0366 0.1325 0.1913
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0006 0.0009
Brugia malayi bHLH-PAS transcription factor 0.013 0.0436 0.0625
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0362 0.1312 0.1308
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0256 0.0909 0.1292
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0063 0.0092
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0061 0.0174 0.0245
Brugia malayi Hhat protein 0.0052 0.0138 0.0194
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0011 0.0019
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0083 0.0709
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0519 0.0745
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0039 0.0051
Echinococcus granulosus cathepsin l1 0.004 0.0094 0.013
Brugia malayi hypothetical protein 0.0061 0.0172 0.0243
Echinococcus multilocularis musashi 0.0025 0.0039 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Onchocerca volvulus 0.0057 0.0159 0.1177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Mycobacterium leprae Possible regulatory protein 0.0046 0.0117 0.0996
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.037 0.1341 0.1919
Schistosoma mansoni hypothetical protein 0.0476 0.1743 0.2521
Toxoplasma gondii FATC domain-containing protein 0.0362 0.1312 0.2549
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni hypothetical protein 0.0267 0.0953 0.1379
Brugia malayi P38 map kinase family protein 2 0.0215 0.0755 0.1087
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0135 0.0452 0.0653
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Brugia malayi AKH receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0139 0.0467 0.067
Loa Loa (eye worm) hypoxia-induced factor 1 0.0545 0.2003 0.2893
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0057 0.0159 0.0898
Giardia lamblia Heat shock protein HSP 90-alpha 0.0315 0.1131 0.155
Onchocerca volvulus 0.0135 0.0452 0.3389
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.037 0.1341 0.194
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0019 0.0021
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0164 0.0231
Onchocerca volvulus 0.0052 0.0138 0.1019
Echinococcus granulosus heat shock protein 90 0.0315 0.1131 0.1632
Schistosoma mansoni pyruvate dehydrogenase 0.0988 0.3673 0.5315
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Bromodomain containing protein 0.0057 0.016 0.0225
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0181 0.0628 0.0885
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0139 0.0467 0.411
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0315 0.1131 1
Echinococcus multilocularis cysteine protease 0.0057 0.0159 0.0155
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0111 0.0362 0.0524
Schistosoma mansoni neuropeptide f receptor 76f 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0238 0.0843 0.1213
Brugia malayi Latrophilin receptor protein 2 0.0042 0.0102 0.0141
Echinococcus granulosus cathepsin L cysteine protease 0.0032 0.0063 0.0086
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.037 0.1341 0.1919
Loa Loa (eye worm) matrix metalloproteinase 0.0114 0.0374 0.0535
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis transmembrane protein nessy, putative 0.0052 0.0138 0.0174
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Schistosoma mansoni heat shock protein 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Brugia malayi Bromodomain containing protein 0.0037 0.0085 0.0116
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0267 0.0953 0.1357
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Trichomonas vaginalis receptor histidine kinase, putative 0.0139 0.0467 0.0651
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Loa Loa (eye worm) phosphatidylinositol 3 0.063 0.2322 0.3355
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0042 0.0102 0.0098
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0362 0.1312 0.1898
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Echinococcus multilocularis cysteine protease 0.0057 0.0159 0.0155
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0016 0.0004 0.0006
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0152 0.0519 0.0745
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0052 0.0138 0.0771
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0163 0.0559 0.0803
Trypanosoma brucei Heat shock protein 83, putative 0.0453 0.1655 0.2394
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0063 0.0092
Plasmodium falciparum endoplasmin, putative 0.0301 0.1078 0.6491
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0366 0.1325 0.1918
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0004 0.0006
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Schistosoma mansoni sterol O-acyltransferase 1 0.029 0.1037 0.15
Schistosoma mansoni endoplasmin 0.0453 0.1655 0.2394
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.002 0.0146
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0004 0.0005
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0139 0.0467 0.411
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Toxoplasma gondii heat shock protein 90, putative 0.0453 0.1655 0.3216
Trichomonas vaginalis DNA topoisomerase II, putative 0.0139 0.0467 0.0651
Onchocerca volvulus 0.0057 0.0159 0.1177
Echinococcus multilocularis serotonin receptor 0.0366 0.1325 0.1322
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0052 0.0138 0.0786
Leishmania major developmentally regulated phosphoprotein-like protein 0.1127 0.4197 0.6072
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0183 0.0636 0.0632
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0445 0.1624 0.235
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0046 0.0117 0.0163
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0039 0.0091 0.0777
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0052 0.0138 0.0266
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Onchocerca volvulus 0.0057 0.0159 0.1177
Brugia malayi Cathepsin L-like precursor 0.004 0.0094 0.013
Entamoeba histolytica cysteine protease, putative 0.0057 0.0159 0.0204
Leishmania major hypothetical protein, conserved 0.0135 0.0452 0.0653
Trypanosoma cruzi heat shock protein 85, putative 0.0315 0.1131 0.1637
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0315 0.1131 0.1637
Echinococcus multilocularis g-protein coupled receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0061 0.0174 0.017
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0315 0.1131 0.3196
Echinococcus multilocularis somatostatin receptor 0.0366 0.1325 0.1322
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1846 0.6912 1
Schistosoma mansoni lamin 0.0025 0.0039 0.0057
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Brugia malayi cathepsin B-like cysteine proteinase 0.017 0.0587 0.0843
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0139 0.0467 0.0651
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1099 0.4092 0.5909
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Echinococcus multilocularis transfer RNA-Lys 0.013 0.0436 0.0432
Schistosoma mansoni cathepsin s 0.0017 0.0009 0.0013
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0015 0.0002 0.0002
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1846 0.6912 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0366 0.1325 0.1913
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0057 0.0159 0.0898
Onchocerca volvulus 0.0057 0.0159 0.1177
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0083 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.1127 0.4197 0.6072
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.017 0.0587 0.0849
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0366 0.1325 0.1322
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi heat shock protein 90, putative 0.0315 0.1131 0.1637
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0135 0.0452 0.0628
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0052 0.0138 0.0194
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0144 0.0202
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0062 0.0177 0.0249
Onchocerca volvulus 0.0366 0.1325 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0063 0.0092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0225 0.0795 0.1144
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.029 0.1037 0.1495
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0184 0.064 0.1241
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0061 0.0174 0.0245
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0004 0.0006
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0045
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0414 0.1508 0.1504
Brugia malayi hypothetical protein 0.013 0.0434 0.0622
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0063 0.0066
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0456 0.1666 0.2405
Echinococcus granulosus neuropeptide receptor A26 0.0366 0.1325 0.1913
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Echinococcus granulosus sterol O acyltransferase 1 0.029 0.1037 0.1495
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0139 0.0467 0.411
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1127 0.4197 0.4194
Toxoplasma gondii type I fatty acid synthase, putative 0.0027 0.0044 0.0083
Brugia malayi neuropeptide F receptor 0.0366 0.1325 0.1913
Leishmania major hypothetical protein, conserved 0.0139 0.0467 0.0676
Echinococcus multilocularis cathepsin b 0.017 0.0587 0.0583
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Echinococcus multilocularis cathepsin b 0.017 0.0587 0.0583
Echinococcus granulosus lamin 0.0025 0.0039 0.0051
Leishmania major DNA topoisomerase ii 0.0139 0.0467 0.0676
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Loa Loa (eye worm) apoptosis regulator protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans thioesterase TesA 0.0017 0.0007 0.0033
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis mitogen activated protein kinase 11 0.0215 0.0755 0.0751
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Entamoeba histolytica acyl-coA synthetase, putative 0.0126 0.042 0.0583
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0004 0.0005
Echinococcus granulosus intermediate filament protein 0.0025 0.0039 0.0051
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0139 0.0467 0.3507
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0016 0.0004 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1846 0.6912 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0028 0.005 0.0045
Schistosoma mansoni sodium-dependent amino acid transporter 0.0061 0.0174 0.0251
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis mitogen activated protein kinase 14 0.0215 0.0755 0.0751
Schistosoma mansoni hypothetical protein 0.0052 0.0138 0.02
Plasmodium falciparum transporter, putative 0.0061 0.0174 0.0987
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Loa Loa (eye worm) ctsf protein 0.0057 0.0159 0.0224
Leishmania major protein kinase, putative 0.0047 0.012 0.0173
Trypanosoma cruzi GUP1, putative 0.0052 0.0138 0.02
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0135 0.0452 0.0447
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0267 0.0953 0.1374
Echinococcus granulosus peptide allatostatin:somatostatin 0.0366 0.1325 0.1913
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0068 0.0064
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0072
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Brugia malayi Calcitonin receptor-like protein seb-1 0.0132 0.0444 0.0636
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1312 0.1893
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni pyruvate dehydrogenase 0.0988 0.3673 0.5315
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Loa Loa (eye worm) hypothetical protein 0.0091 0.0285 0.0407
Echinococcus granulosus aryl hydrocarbon receptor 0.0046 0.0117 0.0163
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0163 0.0559 0.1084
Loa Loa (eye worm) latrophilin receptor protein 2 0.0042 0.0102 0.0141
Toxoplasma gondii hypothetical protein 0.0061 0.0174 0.0335
Echinococcus multilocularis serine protein kinase ATM 0.0362 0.1312 0.1308
Trichomonas vaginalis heat shock protein, putative 0.0162 0.0555 0.0778
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Plasmodium falciparum amino acid transporter, putative 0.0061 0.0174 0.0987
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0119 0.0173
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0366 0.1325 0.1322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0094 0.011
Echinococcus granulosus G protein coupled receptor 139 0.0366 0.1325 0.1913
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0073 0.0218 0.029
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0225 0.0795 0.1144
Leishmania major hypothetical protein, unknown function 0.0135 0.0452 0.0653
Schistosoma mansoni histamine h1 receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1127 0.4197 0.4194
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Loa Loa (eye worm) oxidoreductase 0.0037 0.0083 0.0115
Entamoeba histolytica protein kinase rad3, putative 0.0362 0.1312 0.1877
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0095 0.0301 0.0297
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0016 0.0004 0.0006
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Schistosoma mansoni fkbp-rapamycin associated protein 0.0362 0.1312 0.1898
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0076 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0139 0.0467 0.067
Trypanosoma brucei glycerol uptake protein, putative 0.0052 0.0138 0.02
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0129 0.0432 0.0619
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0139 0.0467 0.411
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0139 0.0469 0.3518
Brugia malayi Matrixin family protein 0.0275 0.0984 0.1418
Echinococcus multilocularis heat shock protein 90 0.0453 0.1655 0.1651
Mycobacterium tuberculosis Polyketide synthase Pks13 0.003 0.0058 0.0481
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Trypanosoma cruzi DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0064 0.0536
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Plasmodium vivax vivapain-1 0.0032 0.0063 0.0332
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus lamin dm0 0.0025 0.0039 0.0051
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0102 0.0098
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) endoplasmin 0.0453 0.1655 0.239
Loa Loa (eye worm) TOPoisomerase family member 0.0139 0.0467 0.067
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trypanosoma cruzi heat shock protein, putative 0.0162 0.0555 0.0803
Echinococcus multilocularis dro:myosuppressin receptor 0.0366 0.1325 0.1322
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0052 0.0138 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0184 0.064 0.0831
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0238 0.084 0.121
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.036 0.1304 0.13
Trypanosoma brucei heat shock protein 90, putative 0.0453 0.1655 0.2394
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0432 0.0619
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0042 0.0102 0.0141
Plasmodium vivax amine transporter, putative 0.0061 0.0174 0.1002
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0016 0.0004 0.0006
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0083 0.0709
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Plasmodium falciparum heat shock protein 90, putative 0.0162 0.0555 0.3306
Trichomonas vaginalis heat shock protein, putative 0.0453 0.1655 0.2374
Toxoplasma gondii PHD-finger domain-containing protein 0.0055 0.0151 0.0291
Loa Loa (eye worm) transcription factor SMAD2 0.0205 0.0717 0.1032
Loa Loa (eye worm) hypothetical protein 0.0062 0.0177 0.0249
Schistosoma mansoni zinc finger protein 0.0019 0.0016 0.0023
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0063 0.018 0.0261
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0184 0.0638 0.0923
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Echinococcus multilocularis allatostatin A receptor 0.0366 0.1325 0.1322
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0039 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0083 0.0709
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0215 0.0755 0.1093
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0083 0.0095
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0075 0.0071
Echinococcus multilocularis expressed conserved protein 0.0041 0.0097 0.0093
Mycobacterium tuberculosis Conserved hypothetical protein 0.0135 0.0452 0.3972
Loa Loa (eye worm) neuropeptide F receptor 0.0366 0.1325 0.1913
Schistosoma mansoni single-minded 0.0176 0.0609 0.0881
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1846 0.6912 1
Loa Loa (eye worm) hhat protein 0.0052 0.0138 0.0194
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0061 0.0173 0.0245
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0181 0.0628 0.3763
Loa Loa (eye worm) hypothetical protein 0.0402 0.1461 0.2109
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0211 0.074 0.1065
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) phosphatidylinositol 3 0.0135 0.0452 0.0647
Echinococcus multilocularis PHD finger protein rhinoceros 0.0055 0.0151 0.0147
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0148 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Schistosoma mansoni hypothetical protein 0.0476 0.1743 0.2521
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0366 0.1325 0.1913
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0366 0.1325 0.1322
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Schistosoma mansoni apoptosis regulator bax 0.0061 0.0174 0.0251
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0162 0.0555 0.0551
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0452 0.0628
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0139 0.0467 0.411
Onchocerca volvulus 0.0366 0.1325 1
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Onchocerca volvulus 0.0366 0.1325 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0159 0.0204
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0068 0.0064
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0447
Leishmania major phosphatidylinositol kinase related protein, putative 0.0135 0.0452 0.0653
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0159 0.0155
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0139 0.0467 0.0651
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0034 0.0071 0.0362
Plasmodium falciparum heat shock protein 90, putative 0.0162 0.0555 0.3306
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0063 0.0066
Schistosoma mansoni vesicular amine transporter 0.0017 0.0007 0.001
Trichomonas vaginalis guanylate cyclase, putative 0.0046 0.0117 0.0142
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0184 0.0638 0.0917
Onchocerca volvulus Fatty acid synthase homolog 0.0036 0.0081 0.0588
Brugia malayi prolyl oligopeptidase family protein 0.0162 0.0554 0.0796
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Schistosoma mansoni lamin 0.0025 0.0039 0.0057
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0103
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0061 0.0174 0.017
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0188 0.0653 0.1267
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0366 0.1325 1
Leishmania major mitochondrial DNA topoisomerase II 0.0139 0.0467 0.0676
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0366 0.1325 0.1918
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0366 0.1325 0.1913
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0139 0.0467 0.411
Loa Loa (eye worm) melatonin receptor type 1A 0.0366 0.1325 0.1913
Brugia malayi cathepsin L-like precursor 0.004 0.0094 0.013
Onchocerca volvulus 0.0366 0.1325 1
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0181 0.0628 0.3753
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0018 0.0011 0.0017
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Giardia lamblia Grp94/Hsp90 0.0315 0.1131 0.155
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0138 0.0174
Schistosoma mansoni biogenic amine (5HT) receptor 0.0366 0.1325 0.1918
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0151 0.0865
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0003
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0206 0.0292
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Loa Loa (eye worm) TAR-binding protein 0.007 0.0206 0.0292
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Onchocerca volvulus Tyrosine kinase homolog 0.0142 0.0481 0.3611
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0432 0.0428
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0177 0.0255
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0017
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0102 0.0141
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0016 0.0004 0.0006
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0119 0.0115
Loa Loa (eye worm) hypothetical protein 0.0132 0.0444 0.0636
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Mycobacterium tuberculosis Polyketide synthase Pks2 0.002 0.0018 0.0125
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0316 0.1136 0.1132
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0084 0.0095
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0366 0.1325 0.1322
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0061 0.0173 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Echinococcus granulosus dro:myosuppressin receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis peregrin 0.0057 0.016 0.0156
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0135 0.0452 0.0875
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0456 0.1666 0.241
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0083 0.0095
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0184 0.064 0.5639
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0052 0.0138 0.02
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Mycobacterium tuberculosis Possible two component sensor kinase 0.0139 0.0467 0.411
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0025 0.0188
Trypanosoma cruzi heat shock protein 90, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0159 0.0224
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Schistosoma mansoni heat shock protein 0.0453 0.1655 0.2394
Loa Loa (eye worm) PHD-finger family protein 0.002 0.002 0.0022
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Brugia malayi Melatonin receptor type 1A 0.0366 0.1325 0.1913
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Brugia malayi ORL1-like opioid receptor 0.0366 0.1325 0.1913
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0285 0.102 0.1453
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0045
Brugia malayi PHD-finger family protein 0.0024 0.0035 0.0045
Echinococcus granulosus GPCR family 2 0.0042 0.0102 0.0141
Loa Loa (eye worm) hypothetical protein 0.0373 0.1351 0.195
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0126 0.042 0.3692
Onchocerca volvulus 0.0025 0.0039 0.0271
Plasmodium vivax heat shock protein, putative 0.0162 0.0555 0.3317
Toxoplasma gondii hypothetical protein 0.0061 0.0174 0.0335
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1846 0.6912 0.6911
Echinococcus granulosus zinc finger protein 0.0019 0.0016 0.0017
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0004 0.0006
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni biogenic amine (5HT) receptor 0.0366 0.1325 0.1918
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0135 0.0452 0.0653
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Onchocerca volvulus Cathepsin F homolog 0.0057 0.0159 0.1177
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0689 0.2546 1
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0086 0.0268 0.0382
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0068 0.013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0042 0.0102 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0016 0.0004 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0126 0.042 0.3692
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Plasmodium vivax acyl-CoA synthetase, putative 0.0094 0.03 0.1766
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0016 0.0004 0.0006
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0377
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0163 0.0559 0.3343
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0135 0.0452 0.2689
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0055 0.0151 0.0219
Plasmodium vivax vivapain-2 0.0057 0.0159 0.0913
Onchocerca volvulus Matrix metalloproteinase homolog 0.0253 0.0898 0.6764
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Schistosoma mansoni hypothetical protein 0.0061 0.0172 0.0249
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Echinococcus multilocularis lamin dm0 0.0025 0.0039 0.0035
Echinococcus granulosus mitogen activated protein kinase 11 0.0215 0.0755 0.1087
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0103
Echinococcus granulosus sex peptide receptor 0.0366 0.1325 0.1913
Schistosoma mansoni neuropeptide F-like receptor 0.0366 0.1325 0.1918
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0148 0.128
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis sterol O acyltransferase 1 0.029 0.1037 0.1033
Brugia malayi AMP-binding enzyme family protein 0.0056 0.0155 0.0218
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Loa Loa (eye worm) hypothetical protein 0.0362 0.1312 0.1893
Brugia malayi heat shock protein 90 0.0453 0.1655 0.239
Echinococcus multilocularis 0.0147 0.0497 0.0493
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0068 0.0064
Plasmodium falciparum enoyl-acyl carrier reductase 0.0184 0.064 0.3824
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0159 0.1177
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0366 0.1325 0.1918
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Echinococcus granulosus Dipeptidyl peptidase 9 0.0054 0.0149 0.0209
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus granulosus alpha 1A adrenergic receptor 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0184 0.064 0.5642
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0016 0.0004 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trichomonas vaginalis heat shock protein, putative 0.0301 0.1078 0.1538
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus serotonin transporter 0.0165 0.0565 0.0812
Echinococcus multilocularis G protein coupled receptor 139 0.0366 0.1325 0.1322
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0139 0.0467 0.411
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1846 0.6912 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.004 0.0094 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Echinococcus multilocularis endoplasmin 0.0315 0.1131 0.1128
Onchocerca volvulus Alhambra homolog 0.0055 0.0151 0.1117
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0135 0.0452 0.2678
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0162 0.0554 0.055
Echinococcus multilocularis sex peptide receptor 0.0366 0.1325 0.1322
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0028 0.005 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Giardia lamblia PHD finger protein 15 0.0055 0.0151 0.0117
Leishmania major pteridine reductase 1 0.0016 0.0004 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis Zinc finger, PHD finger 0.0181 0.0628 0.0624
Echinococcus multilocularis jumonji domain containing protein 0.0077 0.0233 0.0228
Brugia malayi PAS domain containing protein 0.0176 0.0609 0.0875
Loa Loa (eye worm) cysteine protease 0.0057 0.0159 0.0224
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0011 0.0016
Onchocerca volvulus 0.0165 0.0565 0.4249
Onchocerca volvulus 0.0114 0.0374 0.28
Leishmania major hypothetical protein, conserved 0.0052 0.0138 0.02
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0016 0.0004 0.0006
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0021 0.0025 0.0182
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0094 0.0299 0.0433
Loa Loa (eye worm) MH2 domain-containing protein 0.0205 0.0717 0.1032
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Plasmodium falciparum phosphodiesterase delta, putative 0.0034 0.0071 0.0362
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0039 0.0091 0.0777
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0054 0.0149 0.0286
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0099 0.0319 0.0617
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0032 0.0063 0.0092
Brugia malayi hypothetical protein 0.0591 0.2176 0.3144
Echinococcus granulosus tachykinin peptides receptor 99D 0.0546 0.2004 0.2895
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus granulosus 7tm_1 domain containing protein 0.0366 0.1325 0.1913
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0162 0.0555 0.417
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0139 0.0467 0.411
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0366 0.1325 0.1322
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Leishmania major eukaryotic translation initiation factor-like protein 0.002 0.0018 0.0027
Echinococcus granulosus sodium and chloride dependent glycine 0.0225 0.0795 0.1144
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0236 0.0833 0.1182
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0119 0.0167
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0061 0.0174 0.0245
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.042 0.3688
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0034 0.0071 0.0103
Brugia malayi diacylglycerol acyltransferase 0.0052 0.0138 0.0194
Plasmodium vivax phosphodiesterase gamma, putative 0.0034 0.0071 0.0377
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.0419 0.06
Echinococcus granulosus jumonji domain containing protein 0.0077 0.0233 0.033
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0094 0.011
Schistosoma mansoni sodium/chloride dependent transporter 0.0225 0.0795 0.115
Brugia malayi mbt repeat family protein 0.0047 0.0119 0.0167
Echinococcus multilocularis mitogen activated protein kinase 14 0.0215 0.0755 0.0751
Trichomonas vaginalis sensor histidine kinase, putative 0.0139 0.0467 0.0651
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0139 0.0467 0.0651
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0059 0.0167 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Echinococcus granulosus cathepsin b 0.017 0.0587 0.0843
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni DNA topoisomerase II 0.0139 0.0467 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Echinococcus multilocularis potassium voltage gated channel protein 0.0062 0.0177 0.0172
Echinococcus multilocularis aryl hydrocarbon receptor 0.0046 0.0117 0.0112
Echinococcus granulosus PHD finger protein rhinoceros 0.0055 0.0151 0.0213
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0009 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Loa Loa (eye worm) hypothetical protein 0.0095 0.0301 0.0429
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0061 0.0174 0.0245
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0009 0.0007
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Brugia malayi Cathepsin L-like precursor 0.004 0.0094 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.0129
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0139 0.0467 0.411
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0245 0.087 0.1235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0306 0.1099 0.1568
Giardia lamblia Hypothetical protein 0.0135 0.0452 0.0556
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0028 0.005 0.0045
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0366 0.1325 0.1918
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Brugia malayi translation initiation factor 4E 0.002 0.0018 0.002
Schistosoma mansoni sodium/chloride dependent transporter 0.0226 0.0798 0.1154
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0061 0.0174 0.0251
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Trichomonas vaginalis guanylate cyclase, putative 0.0046 0.0117 0.0142
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Leishmania major cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii Hsp90 domain-containing protein 0.0162 0.0555 0.1076
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1846 0.6912 1
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0102 0.0141
Entamoeba histolytica hypothetical protein 0.0306 0.1099 0.1568
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0159 0.0155
Schistosoma mansoni hypothetical protein 0.0091 0.0285 0.0413
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0068 0.0064
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0025 0.0039 0.0271
Echinococcus multilocularis neuropeptide FF receptor 2 0.0366 0.1325 0.1322
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.063 0.2322 0.2319
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0043 0.0107 0.0148
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0042 0.0102 0.0098
Onchocerca volvulus 0.0061 0.0174 0.1287
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Brugia malayi sulfakinin receptor protein 0.0366 0.1325 0.1913
Plasmodium falciparum phd finger protein, putative 0.0055 0.0151 0.085
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0052 0.0138 0.0194
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Mycobacterium leprae Probable two-component sensor kinase 0.0139 0.0467 0.4106
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.005 0.0248
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0016 0.0004 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0039 0.0091 0.0777
Echinococcus granulosus endoplasmin 0.0315 0.1131 0.1632
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0052 0.0138 0.0134
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0184 0.0638 0.0917
Echinococcus multilocularis tar DNA binding protein 0.007 0.0206 0.0202
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0139 0.0467 0.3507
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Schistosoma mansoni pyruvate dehydrogenase 0.1127 0.4197 0.6072
Loa Loa (eye worm) hypothetical protein 0.0042 0.0101 0.014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0419 0.0606
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Mycobacterium leprae Probable two component sensor kinase MprB 0.0139 0.0467 0.4106
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0159 0.0155
Onchocerca volvulus 0.013 0.0436 0.3272
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0776 0.2874 0.4159
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0119 0.0173
Toxoplasma gondii target of rapamycin (TOR), putative 0.1377 0.5142 1
Onchocerca volvulus 0.0057 0.0159 0.1177
Schistosoma mansoni hypothetical protein 0.0041 0.0097 0.0141
Brugia malayi Dopamine receptor protein 1 0.0366 0.1325 0.1913
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0083 0.0709
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0139 0.0467 0.411
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0063 0.0086
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0095 0.0301 0.0297
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0083 0.0095
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0016 0.0004 0.0006
Loa Loa (eye worm) phosphatidylinositol 3 0.1846 0.6912 1
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0162 0.0555 0.0778
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0083 0.0453
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.0051
Onchocerca volvulus Neuropeptide F receptor homolog 0.0366 0.1325 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0228 0.0804 0.1164
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Mycobacterium ulcerans polyketide synthase 0.0021 0.0025 0.0188
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus multilocularis lamin 0.0025 0.0039 0.0035
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.002 0.002 0.0023
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0039 0.0091 0.0771
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Onchocerca volvulus 0.0046 0.0117 0.0855
Loa Loa (eye worm) hypothetical protein 0.0047 0.0119 0.0167
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0042 0.0102 0.0141
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0017 0.0007 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0063 0.018 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0184 0.0638 0.0899
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.2966
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.1099 0.4092 0.5909
Echinococcus multilocularis geminin 0.0476 0.1743 0.1739
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Entamoeba histolytica cysteine proteinase 2 0.0032 0.0063 0.0066
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0068 0.0099
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Echinococcus multilocularis serotonin transporter 0.0165 0.0565 0.0561
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Schistosoma mansoni hypothetical protein 0.0283 0.1012 0.1464
Plasmodium vivax hypothetical protein, conserved 0.0139 0.0467 0.2784
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.003 0.0058 0.0481
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Echinococcus multilocularis neuropeptide receptor A26 0.0366 0.1325 0.1322
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0147 0.0497 0.2955
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0028 0.005 0.0093
Onchocerca volvulus 0.0056 0.0155 0.1145
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0132 0.0444 0.0636
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1846 0.6912 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0362 0.1312 0.1893
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1846 0.6912 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0016 0.0004 0.0006
Brugia malayi Probable DNA topoisomerase II 0.0139 0.0467 0.067
Entamoeba histolytica hypothetical protein 0.0073 0.0218 0.029
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0366 0.1325 0.1322
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0132 0.0444 0.0636
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0083 0.0709
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0042 0.01 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0068 0.0093
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0126 0.042 0.3692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Mycobacterium leprae Polyketide synthase Pks13 0.003 0.0058 0.0475
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Trichomonas vaginalis conserved hypothetical protein 0.0402 0.1461 0.2093
Echinococcus granulosus sodium and chloride dependent glycine 0.0225 0.0795 0.1144
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0095 0.0301 0.0429
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Echinococcus granulosus cysteine protease 0.0032 0.0063 0.0086
Toxoplasma gondii heat shock protein 75, putative 0.0162 0.0555 0.1076
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0095 0.0301 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0116 0.0167
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0647
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.002 0.0146
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0215 0.0755 0.1087
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Loa Loa (eye worm) hhat protein 0.0052 0.0138 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0061 0.0173 0.0245
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0021 0.0025 0.0188
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0139 0.0468 0.4113
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0174 0.0251
Echinococcus multilocularis cathepsin L 0.0032 0.0063 0.0059
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.063 0.2322 0.3359
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0034 0.0071 0.0097
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0009 0.0013
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0183 0.0636 0.0915
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0054 0.0149 0.0145
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0043 0.0107 0.0102
Chlamydia trachomatis DNA gyrase subunit B 0.0139 0.0467 0.6291
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0162 0.0554 0.0796
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Echinococcus multilocularis G-protein coupled receptor, putative 0.0366 0.1325 0.1322
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0129 0.0432 0.0619
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0016 0.0004 0.0006
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0184 0.0638 0.0634
Mycobacterium ulcerans putative regultory protein 0.0139 0.0467 0.411
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0016 0.0004 0.0006
Mycobacterium ulcerans two component sensor kinase MprB 0.0139 0.0467 0.411
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0139 0.0467 0.0676
Plasmodium vivax hypothetical protein 0.0135 0.0452 0.2689
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0046 0.0117 0.0112
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0054 0.0149 0.0215
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0039 0.0091 0.0777
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Brugia malayi Hemopexin family protein 0.0162 0.0554 0.0795
Schistosoma mansoni alpha-1 adrenergic receptor 0.0366 0.1325 0.1918
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0159 0.0224
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0027 0.0032
Schistosoma mansoni hypothetical protein 0.0018 0.0011 0.0017
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0052 0.0138 0.0194
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0061 0.0174 0.0245
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Brugia malayi Bromodomain containing protein 0.0073 0.022 0.0312
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.002 0.0018 0.002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0445 0.1624 0.2345
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.002 0.0018 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0039 0.0091 0.0777
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0366 0.1325 0.1913
Echinococcus granulosus somatostatin receptor 0.0366 0.1325 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Brugia malayi mbt repeat family protein 0.0047 0.0119 0.0167
Trypanosoma cruzi GUP1, putative 0.0052 0.0138 0.02
Echinococcus granulosus heat shock protein 90 0.0453 0.1655 0.239
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0016 0.0004 0.0006
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.037 0.1341 0.1919
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0144 0.0139
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0063 0.0086
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0366 0.1325 0.1913
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Chlamydia trachomatis DNA gyrase subunit B 0.0139 0.0467 0.6291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Brugia malayi prolyl oligopeptidase family protein 0.0054 0.0149 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0362
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0432 0.0428
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Giardia lamblia GTOR 0.1846 0.6912 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8 uM Concentration of the compound required to inhibit Acyl coenzyme A:cholesterol acyltransferase 1 ChEMBL. 15149654
IC50 (binding) = 8 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 2 expressed in Hi5 cells ChEMBL. 15603959
IC50 (binding) = 8 uM Concentration of the compound required to inhibit Acyl coenzyme A:cholesterol acyltransferase 1 ChEMBL. 15149654
IC50 (binding) = 8 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 2 expressed in Hi5 cells ChEMBL. 15603959
IC50 (binding) = 39 uM Concentration of the compound required to inhibit Acyl coenzyme A:cholesterol acyltransferase 2 ChEMBL. 15149654
IC50 (binding) = 39 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 1 expressed in Hi5 cells ChEMBL. 15603959
IC50 (binding) = 39 uM Concentration of the compound required to inhibit Acyl coenzyme A:cholesterol acyltransferase 2 ChEMBL. 15149654
IC50 (binding) = 39 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 1 expressed in Hi5 cells ChEMBL. 15603959

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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