Detailed information for compound 1819452

Basic information

Technical information
  • TDR Targets ID: 1819452
  • Name: (1R,2R)-1-(3,4-dimethoxyphenyl)-2-[4-[(2S,3R, 4R,5S)-5-(3,4-dimethoxyphenyl)-3,4-dimethylox olan-2-yl]-2-methoxyphenoxy]propan-1-ol
  • MW: 552.655 | Formula: C32H40O8
  • H donors: 1 H acceptors: 1 LogP: 5.6 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(ccc1O[C@@H]([C@@H](c1ccc(c(c1)OC)OC)O)C)[C@H]1O[C@@H]([C@@H]([C@H]1C)C)c1ccc(c(c1)OC)OC
  • InChi: 1S/C32H40O8/c1-18-19(2)32(40-31(18)22-10-13-25(35-5)28(16-22)37-7)23-11-14-26(29(17-23)38-8)39-20(3)30(33)21-9-12-24(34-4)27(15-21)36-6/h9-20,30-33H,1-8H3/t18-,19-,20-,30+,31+,32+/m1/s1
  • InChiKey: JYXVAMLAJSGCDL-PLCQSOOISA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1R,2R)-1-(3,4-dimethoxyphenyl)-2-[4-[(2S,3R,4R,5S)-5-(3,4-dimethoxyphenyl)-3,4-dimethyl-tetrahydrofuran-2-yl]-2-methoxy-phenoxy]propan-1-ol
  • (1R,2R)-1-(3,4-dimethoxyphenyl)-2-[4-[(2S,3R,4R,5S)-5-(3,4-dimethoxyphenyl)-3,4-dimethyl-2-tetrahydrofuranyl]-2-methoxyphenoxy]propan-1-ol
  • (1R,2R)-1-(3,4-dimethoxyphenyl)-2-[4-[(2S,3R,4R,5S)-5-(3,4-dimethoxyphenyl)-3,4-dimethyl-oxolan-2-yl]-2-methoxy-phenoxy]propan-1-ol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) References
Homo sapiens endothelial PAS domain protein 1 References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Brugia malayi hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) hypoxia-induced factor 1 Get druggable targets OG5_131074 All targets in OG5_131074
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131074 All targets in OG5_131074
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0139 0.0467 0.411
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0037 0.0085 0.0117
Echinococcus granulosus g-protein coupled receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0061 0.0173 0.0169
Brugia malayi PHD-finger family protein 0.0055 0.0151 0.0213
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0419 0.0606
Brugia malayi jmjC domain containing protein 0.0126 0.0419 0.06
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0089 0.017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.063 0.2322 0.3355
Trypanosoma brucei heat shock protein 84, putative 0.0162 0.0555 0.0803
Plasmodium falciparum cysteine proteinase falcipain 3 0.0057 0.0159 0.0898
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0063 0.018 0.0261
Schistosoma mansoni adenoreceptor 0.0366 0.1325 0.1918
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.0219
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Brugia malayi putative neuropeptide receptor NPR1 0.0366 0.1325 0.1913
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0162 0.0554 0.0802
Entamoeba histolytica cysteine proteinase 1, putative 0.0032 0.0063 0.0066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0181 0.0628 0.0903
Loa Loa (eye worm) phosphatidylinositol 3 0.0135 0.0452 0.0647
Entamoeba histolytica heat shock protein 90, putative 0.0453 0.1655 0.2374
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0027 0.0022
Loa Loa (eye worm) cathepsin B 0.0063 0.018 0.0255
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0034 0.0071 0.0097
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0062 0.0177 0.0249
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.002 0.002 0.014
Echinococcus multilocularis GPCR, family 2 0.0042 0.0102 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Trichomonas vaginalis PIKK family atypical protein kinase 0.1244 0.4638 0.6702
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0083 0.0438
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Trichomonas vaginalis adenylate cyclase, putative 0.0046 0.0117 0.0142
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0039 0.0091 0.0777
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Echinococcus granulosus phd:f box containing protein 0.0033 0.0068 0.0093
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0034 0.0071 0.0067
Echinococcus granulosus 7TM GPCR rhodopsin 0.0366 0.1325 0.1913
Plasmodium vivax hypothetical protein, conserved 0.0135 0.0452 0.2689
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0206 0.0292
Leishmania major hypothetical protein, conserved 0.0033 0.0068 0.0099
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0052 0.0138 0.02
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0139 0.0467 0.3311
Echinococcus multilocularis lysine specific demethylase 5A 0.0124 0.0412 0.0407
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0362 0.1312 0.1877
Schistosoma mansoni zinc finger protein 0.0052 0.0138 0.02
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0362 0.1312 0.1898
Mycobacterium leprae PROBABLE HYDROLASE 0.0139 0.0468 0.411
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0164 0.0159
Plasmodium vivax heat shock protein 86, putative 0.0453 0.1655 1
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0068 0.013
Echinococcus multilocularis neuropeptides capa receptor 0.0366 0.1325 0.1322
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0006 0.0009
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0245 0.087 0.1259
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Onchocerca volvulus 0.0366 0.1325 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0135 0.0452 0.0653
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0083 0.0709
Echinococcus granulosus neuropeptide FF receptor 2 0.0366 0.1325 0.1913
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0139 0.0467 0.0676
Toxoplasma gondii cathepsin CPL 0.0057 0.0159 0.0306
Echinococcus granulosus neuropeptide Y receptor 0.0366 0.1325 0.1913
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) G-protein coupled receptor 0.0366 0.1325 0.1913
Trypanosoma cruzi DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Echinococcus multilocularis mitogen activated protein kinase 11 0.0215 0.0755 0.0751
Echinococcus granulosus hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0647
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0135 0.0452 0.0647
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1473 0.5505 0.7964
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0181 0.0628 0.1219
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Plasmodium falciparum acyl-CoA synthetase 0.0094 0.03 0.1753
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0057 0.0159 0.1177
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0006
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0056 0.0155 0.0218
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0061 0.0172 0.0168
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0119 0.0115
Brugia malayi Dopamine receptor 0.0366 0.1325 0.1913
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0144 0.0202
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Brugia malayi SH2 domain containing protein 0.017 0.0584 0.0839
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0428 0.0594
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0083 0.0121
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0177 0.0255
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.017 0.0584 0.0839
Brugia malayi Tachykinin-like peptides receptor 99D 0.0366 0.1325 0.1913
Mycobacterium ulcerans polyketide synthase 0.002 0.002 0.0146
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.002 0.0018 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0006 0.0002
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0083 0.0159
Loa Loa (eye worm) RNA binding protein 0.007 0.0206 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0016 0.0004 0.0006
Brugia malayi GnHR receptor homolog 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0069 0.0204 0.0289
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma brucei cysteine peptidase C (CPC) 0.0063 0.018 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0009 0.0013
Treponema pallidum heat shock protein 90 0.0315 0.1131 1
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0116 0.0167
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0139 0.0467 0.0905
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0414 0.1508 0.2176
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0445 0.1624 0.1621
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0139 0.0467 0.411
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0028 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0184 0.064 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0184 0.0638 0.0899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0159 0.0204
Brugia malayi RE15519p 0.0366 0.1325 0.1913
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0144 0.0202
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0139 0.0467 0.0651
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0095 0.0301 0.0435
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.005 0.0232
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0159 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0126 0.042 0.3692
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0135 0.0452 0.0653
Brugia malayi RNA binding protein 0.007 0.0206 0.0292
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0139 0.0467 0.411
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0165 0.0565 0.0812
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0362 0.1312 0.1898
Loa Loa (eye worm) heat shock protein 90 0.0453 0.1655 0.239
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Leishmania major protein kinase, putative 0.0052 0.0139 0.0202
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0366 0.1325 0.1322
Loa Loa (eye worm) TYRA-2 protein 0.0366 0.1325 0.1913
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0068 0.0346
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0163 0.0559 0.1084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Echinococcus granulosus geminin 0.0476 0.1743 0.2516
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Brugia malayi intermediate filament protein 0.0025 0.0039 0.0051
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0139 0.0468 0.0671
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0094 0.03 0.2624
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus neuropeptide receptor 0.0366 0.1325 0.1913
Mycobacterium ulcerans heat shock protein 90 0.0315 0.1131 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0046 0.0117 0.0142
Schistosoma mansoni myosin xvIII 0.0366 0.1325 0.1918
Echinococcus granulosus orexin receptor type 2 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.013 0.0434 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Echinococcus granulosus cathepsin L 0.0032 0.0063 0.0086
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0139 0.0467 0.067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus granulosus expressed conserved protein 0.0041 0.0097 0.0135
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.1127 0.4197 0.6069
Trypanosoma brucei glycerol uptake protein, putative 0.0052 0.0138 0.02
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0199 0.0693 0.0909
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0052 0.0138 0.0134
Brugia malayi Hsp90 protein 0.0162 0.0555 0.0797
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.1127 0.4197 0.6069
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0034 0.0071 0.0067
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0075 0.0103
Echinococcus multilocularis neuropeptide s receptor 0.0366 0.1325 0.1322
Toxoplasma gondii PHD-finger domain-containing protein 0.0055 0.0151 0.0291
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0083 0.0709
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0139 0.0467 0.411
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0034 0.0071 0.0362
Schistosoma mansoni bromodomain containing protein 0.0062 0.0177 0.0256
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0093
Echinococcus multilocularis neuropeptide receptor 0.0366 0.1325 0.1322
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1312 0.1893
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0366 0.1325 0.1322
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0028 0.005 0.0072
Loa Loa (eye worm) PDE1B protein 0.0445 0.1624 0.2345
Onchocerca volvulus 0.0072 0.0216 0.161
Brugia malayi hypothetical protein 0.0042 0.01 0.0139
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0018 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.036 0.1304 0.1882
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Mycobacterium ulcerans hydrolase 0.0139 0.0468 0.4113
Giardia lamblia DNA repair protein RAD52 0.0256 0.0909 0.1225
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.002 0.002 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0094 0.011
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0159 0.023
Echinococcus granulosus allatostatin A receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0184 0.064 0.3833
Loa Loa (eye worm) hypothetical protein 0.0057 0.0159 0.0224
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0083 0.0159
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0366 0.1325 0.1918
Trypanosoma cruzi target of rapamycin kinase 3 0.1473 0.5505 0.7964
Mycobacterium ulcerans polyketide synthase Pks13 0.003 0.0058 0.0481
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0363 0.1313 0.1894
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0366 0.1325 0.1913
Loa Loa (eye worm) phosphatidylinositol 3 0.0147 0.0497 0.0713
Echinococcus granulosus cathepsin b 0.017 0.0587 0.0843
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0057 0.0159 0.0224
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus granulosus mitogen activated protein kinase 14 0.0215 0.0755 0.1087
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0135 0.0452 0.0647
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0021 0.0025 0.0182
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0038 0.0088 0.0122
Mycobacterium tuberculosis Conserved protein 0.0139 0.0467 0.411
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Trichomonas vaginalis endoplasmin, putative 0.0301 0.1078 0.1538
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Echinococcus granulosus tar DNA binding protein 0.007 0.0206 0.0292
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Giardia lamblia Pms1-like protein 0.0139 0.0467 0.0579
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0174 0.1002
Leishmania major phosphatidylinositol 3-kinase, putative 0.0181 0.0628 0.0909
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0016 0.0004 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0126 0.042 0.0583
Brugia malayi G-protein coupled receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0102 0.0141
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0052 0.0138 0.0134
Plasmodium vivax vivapain-3 0.0032 0.0063 0.0332
Echinococcus multilocularis orexin receptor type 2 0.0366 0.1325 0.1322
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1473 0.5505 0.7964
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0162 0.0555 0.0797
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0025 0.0188
Echinococcus granulosus peregrin 0.0057 0.016 0.0225
Schistosoma mansoni heat shock protein 0.0162 0.0555 0.0803
Plasmodium falciparum DNA gyrase subunit B 0.0139 0.0467 0.2772
Echinococcus multilocularis neuropeptides capa receptor 0.0366 0.1325 0.1322
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0016 0.0005 0.0007
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.002 0.0018 0.0027
Plasmodium falciparum heat shock protein 90 0.0453 0.1655 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0251 0.0892 0.1267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Schistosoma mansoni aryl hydrocarbon receptor 0.0176 0.0609 0.0881
Brugia malayi larval opioid receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0093
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0139 0.0467 0.4106
Schistosoma mansoni hypothetical protein 0.0162 0.0554 0.0801
Brugia malayi TAR-binding protein 0.007 0.0206 0.0292
Brugia malayi putative neuropeptide receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Toxoplasma gondii heat shock protein HSP90 0.0453 0.1655 0.3216
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Onchocerca volvulus 0.0057 0.0159 0.1177
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Mycobacterium tuberculosis Probable thioesterase TesA 0.0017 0.0007 0.0033
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0052 0.0138 0.0134
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0181 0.0628 0.0909
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0211 0.074 0.1065
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0016 0.0004 0.0006
Loa Loa (eye worm) serotonin transporter b 0.0165 0.0565 0.0812
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Onchocerca volvulus 0.0037 0.0083 0.0605
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0135 0.0452 0.3389
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Plasmodium vivax heat shock protein 90, putative 0.0162 0.0555 0.3317
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Onchocerca volvulus 0.0061 0.0174 0.1287
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0021 0.0025 0.0188
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0144 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0148 0.0214
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0176 0.0608 0.0855
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0245 0.087 0.1259
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0432 0.0619
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0452 0.0647
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0016 0.0004 0.0006
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Echinococcus granulosus fmrfamide receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0163 0.0559 0.0555
Brugia malayi follicle stimulating hormone receptor 0.0366 0.1325 0.1913
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0366 0.1324 0.2573
Echinococcus granulosus potassium voltage gated channel protein 0.0062 0.0177 0.0249
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0139 0.0467 0.411
Echinococcus granulosus neuropeptide s receptor 0.0366 0.1325 0.1913
Treponema pallidum sodium- and chloride- dependent transporter 0.0165 0.0565 0.43
Leishmania major hypothetical protein, conserved 0.0034 0.0071 0.0103
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0507 0.1859 0.267
Loa Loa (eye worm) hypothetical protein 0.0267 0.0953 0.1374
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0061 0.0174 0.0245
Brugia malayi MH2 domain containing protein 0.0205 0.0717 0.1032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0082 0.0113
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0034 0.0071 0.0103
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0126 0.042 0.3692
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0591 0.2176 0.3144
Onchocerca volvulus Matrilysin homolog 0.0114 0.0374 0.28
Brugia malayi Dopamine receptor protein 2 0.0366 0.1325 0.1913
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0148 0.0285
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0504 0.1848 0.3591
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0139 0.0467 0.0676
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0119 0.0173
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0052 0.0138 0.0194
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.036 0.1304 0.1882
Echinococcus granulosus heat shock protein 0.0453 0.1655 0.239
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0287 0.1029 0.1489
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Onchocerca volvulus Matrilysin homolog 0.0253 0.0898 0.6764
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0119 0.0876
Echinococcus granulosus cathepsin L cysteine proteinase 0.0057 0.0159 0.0224
Mycobacterium ulcerans two component regulator - sensor kinase 0.0139 0.0467 0.411
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0054 0.0149 0.0215
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0147 0.0497 0.0713
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0546 0.2004 0.2001
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.002 0.0018 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0366 0.1325 0.1322
Loa Loa (eye worm) hypothetical protein 0.0225 0.0795 0.1144
Echinococcus granulosus serotonin receptor 0.0366 0.1325 0.1913
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.037 0.1341 0.1935
Loa Loa (eye worm) hypothetical protein 0.017 0.0587 0.0843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0882 0.3272 0.4734
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni sodium/chloride dependent transporter 0.0165 0.0565 0.0818
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0052 0.0138 0.0194
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0126 0.042 0.3692
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0139 0.0467 0.2772
Giardia lamblia Phosphatidylinositol 4-kinase 0.0147 0.0497 0.0623
Onchocerca volvulus 0.0061 0.0174 0.1287
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Plasmodium vivax endoplasmin, putative 0.0453 0.1655 1
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0139 0.0467 0.411
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0228 0.0804 0.114
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0016 0.0004 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0494 0.069
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0494 0.069
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0143 0.0482 0.0934
Onchocerca volvulus 0.0126 0.042 0.315
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Loa Loa (eye worm) norepinephrine transporter 0.0165 0.0565 0.0812
Schistosoma mansoni endoplasmin 0.0453 0.1655 0.2394
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0046 0.0117 0.0142
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0119 0.0167
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0139 0.0467 0.0905
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0061 0.0174 0.017
Loa Loa (eye worm) solute carrier family 6 member 4 0.0165 0.0565 0.0812
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0009
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0091 0.0285 0.0407
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.001
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0165 0.0565 0.0818
Entamoeba histolytica heat shock protein 90, putative 0.0453 0.1655 0.2374
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0225 0.0795 0.1144
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0267 0.0953 0.095
Loa Loa (eye worm) hypothetical protein 0.0037 0.0083 0.0115
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0377
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0139 0.0467 0.067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0452 0.0647
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0144 0.0208
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0139 0.0467 0.411
Brugia malayi FAT domain containing protein 0.0267 0.0953 0.1374
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0016 0.0004 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0245 0.087 0.1253
Echinococcus multilocularis sodium and chloride dependent glycine 0.0225 0.0795 0.0791
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Onchocerca volvulus 0.013 0.0434 0.3258
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Toxoplasma gondii hypothetical protein 0.0052 0.0138 0.0266
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0362
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0159 0.1177
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0295 0.1057 0.1507
Mycobacterium leprae Probable polyketide synthase Pks1 0.0021 0.0025 0.0182
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi G protein-coupled receptor 0.0366 0.1325 0.1913
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0083 0.0115
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0445 0.1624 0.2345
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0083 0.0703
Brugia malayi Cathepsin L-like cysteine proteinase 0.004 0.0094 0.013
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0316 0.1136 0.1638
Loa Loa (eye worm) hypothetical protein 0.0053 0.0144 0.0202
Schistosoma mansoni hypothetical protein 0.002 0.002 0.0028
Leishmania major hypothetical protein, conserved 0.0034 0.0071 0.0103
Schistosoma mansoni cytochrome P450 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0139 0.0467 0.067
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0139 0.0467 0.3507
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0366 0.1325 0.1913
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0076 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Trypanosoma brucei DNA topoisomerase ii 0.0139 0.0467 0.0676
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0034 0.0071 0.0097
Onchocerca volvulus 0.0366 0.1325 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Plasmodium falciparum cysteine proteinase falcipain 1 0.0032 0.0063 0.0316
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0139 0.0467 0.0463
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Loa Loa (eye worm) phosphatidylinositol 3 0.0111 0.0362 0.0518
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Loa Loa (eye worm) heat shock protein 75 0.0162 0.0555 0.0797
Onchocerca volvulus 0.0366 0.1325 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.017 0.0587 0.0849
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0366 0.1325 1
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0139 0.0467 0.0676
Loa Loa (eye worm) translation initiation factor 4E 0.002 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi Endoplasmin precursor 0.0453 0.1655 0.239
Loa Loa (eye worm) MBCTL1 0.0053 0.0144 0.0202
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0061 0.0172 0.0243
Trypanosoma cruzi glycerol uptake protein, putative 0.0052 0.0138 0.02
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0159 0.0155
Schistosoma mansoni growth hormone secretagogue receptor 0.0366 0.1325 0.1918
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0061 0.0174 0.0169
Schistosoma mansoni polycystin 1-related 0.0061 0.0172 0.0249
Echinococcus multilocularis heat shock protein 90 0.0315 0.1131 0.1128
Schistosoma mansoni cathepsin F (C01 family) 0.004 0.0094 0.0136
Trypanosoma cruzi cruzipain precursor, putative 0.0057 0.0159 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.017 0.0587 0.0849
Mycobacterium ulcerans acyl-CoA synthetase 0.0126 0.042 0.3692
Trichomonas vaginalis hypothetical protein 0.0184 0.064 0.0902
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0083 0.0703
Onchocerca volvulus Glucosylceramidase homolog 0.0138 0.0466 0.3499
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0052 0.0138 0.0266
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0039 0.0091 0.0777
Brugia malayi PHD-finger family protein 0.002 0.0019 0.0021
Echinococcus granulosus cathepsin l1 0.0057 0.0159 0.0224
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0366 0.1325 0.1913
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.002 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Echinococcus granulosus neuropeptide Y receptor 0.0366 0.1325 0.1913
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Echinococcus multilocularis fmrfamide receptor 0.0366 0.1325 0.1322
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0068 0.0099
Loa Loa (eye worm) matrixin family protein 0.0275 0.0984 0.1418
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0016 0.0004 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.037 0.1341 0.1919
Loa Loa (eye worm) hypothetical protein 0.0037 0.0083 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Entamoeba histolytica hypothetical protein 0.0362 0.1312 0.1877
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Plasmodium falciparum DNA topoisomerase 2 0.0139 0.0467 0.2772
Mycobacterium ulcerans DNA gyrase subunit B 0.0139 0.0467 0.411
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0056 0.0155 0.1341
Echinococcus granulosus lysine specific demethylase 5A 0.0126 0.0419 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0452 0.0628
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0231 0.0816 0.1088
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0034 0.0071 0.0097
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0046 0.0117 0.0163
Entamoeba histolytica DNA topoisomerase II, putative 0.0139 0.0467 0.0651
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0094 0.03 0.2698
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Loa Loa (eye worm) matrixin family protein 0.0253 0.0898 0.1293
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0016 0.0005 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Echinococcus multilocularis fmrfamide receptor 0.0366 0.1325 0.1322
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0362 0.1312 0.1898
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.0213
Echinococcus multilocularis zinc finger protein 0.0019 0.0016 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1846 0.6912 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0366 0.1325 0.1918
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0315 0.1131 0.1632
Brugia malayi jmjC domain containing protein 0.0238 0.084 0.121
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0091 0.0777
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0174 0.0251
Echinococcus multilocularis heat shock protein 0.0453 0.1655 0.1651
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0009 0.0007
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0245 0.087 0.1235
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Loa Loa (eye worm) G-protein coupled receptor 0.0366 0.1325 0.1913
Leishmania major phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0228 0.0804 0.1158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0063 0.0092
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0245 0.087 0.1235
Loa Loa (eye worm) phosphatidylinositol 3 0.0392 0.1424 0.2056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0039 0.0091 0.0777
Echinococcus granulosus serine protein kinase ATM 0.0362 0.1312 0.1893
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0083 0.0079
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0016 0.0004 0.0006
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0016 0.0004 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0017 0.0006 0.0023
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0148 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Plasmodium vivax vivapain-2 0.0057 0.0159 0.0913
Loa Loa (eye worm) hypothetical protein 0.0139 0.0468 0.0671
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi G protein-coupled receptor F59B2.13 0.0366 0.1325 0.1913
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0054 0.0149 0.0215
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Echinococcus granulosus neuropeptides capa receptor 0.0366 0.1325 0.1913
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0147 0.0497 0.0713
Entamoeba histolytica hypothetical protein 0.0052 0.0138 0.0174
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0006 0.0009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0366 0.1325 0.1913
Echinococcus granulosus neuropeptides capa receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Leishmania major phosphatidylinositol 3-kinase, putative 0.063 0.2322 0.3359
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Plasmodium vivax JmjC domain containing protein 0.0033 0.0068 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Loa Loa (eye worm) jmjC domain-containing protein 0.0114 0.0372 0.0533
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.063 0.2322 0.3359
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0016 0.0004 0.0006
Mycobacterium ulcerans putative regulatory protein 0.013 0.0436 0.3835
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0028 0.005 0.0066
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0021 0.0025 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Echinococcus multilocularis sodium and chloride dependent glycine 0.0225 0.0795 0.0791
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0009
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0139 0.0467 0.411
Schistosoma mansoni transcription factor LCR-F1 0.0061 0.0172 0.0249
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0068 0.0099
Trypanosoma cruzi heat shock protein 85, putative 0.0453 0.1655 0.2394
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0163 0.0559 0.0809
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.063 0.2322 0.3355
Onchocerca volvulus 0.004 0.0094 0.0683
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.037 0.1341 0.194
Plasmodium vivax DNA gyrase subunit B, putative 0.0139 0.0467 0.2784
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trypanosoma brucei heat shock protein 90, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0366 0.1325 0.1918
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0139 0.0467 0.0651
Brugia malayi G-protein coupled receptor 0.0366 0.1325 0.1913
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0061 0.0174 0.0245
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0061 0.0174 0.0169
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Onchocerca volvulus 0.0042 0.0104 0.076
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0135 0.0452 0.0875
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0052 0.0138 0.0194
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Leishmania major eukaryotic translation initiation factor-like 0.002 0.0018 0.0027
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Plasmodium vivax unspecified product 0.0032 0.0063 0.0332
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0139 0.0467 0.411
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0083 0.0115
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Giardia lamblia Heat shock protein HSP 90-alpha 0.0453 0.1655 0.2315
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0315 0.1131 1
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0402 0.1461 0.2839
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Loa Loa (eye worm) hypothetical protein 0.0046 0.0117 0.0163
Leishmania major oxidoreductase-like protein 0.0016 0.0004 0.0005
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0103
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0009 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0804 0.114
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Loa Loa (eye worm) hypothetical protein 0.0055 0.0152 0.0213
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0048 0.0123 0.0172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Echinococcus granulosus biogenic amine 5HT receptor 0.0366 0.1325 0.1913
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0135 0.0452 0.0653
Echinococcus granulosus cathepsin l cysteine peptidase 0.0057 0.0159 0.0224
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) phosphatidylinositol 3 0.014 0.0472 0.0677
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0184 0.064 0.5642
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0016 0.0004 0.0006
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0052 0.0138 0.02
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1322
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0006 0.0002
Brugia malayi hypoxia-induced factor 1 0.0545 0.2003 0.2893
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1846 0.6912 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.042 0.3688
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0159 0.0204
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0184 0.0638 0.0899
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0068 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Echinococcus granulosus neuropeptide receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0335
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0148 0.0214
Schistosoma mansoni hypothetical protein 0.0135 0.0452 0.0653
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0052 0.0138 0.0134
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0135 0.0452 0.2689
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1322
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0042 0.0102 0.0141
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0366 0.1325 0.1322
Trichomonas vaginalis receptor histidine kinase, putative 0.0139 0.0467 0.0651
Plasmodium falciparum phosphodiesterase gamma, putative 0.0034 0.0071 0.0362
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Leishmania major phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0366 0.1325 0.1913
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0021
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0061 0.0174 0.0245
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0016 0.0004 0.0006
Schistosoma mansoni jumonji domain containing protein 0.02 0.0701 0.1013
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0119 0.0167
Trypanosoma brucei developmentally regulated phosphoprotein 0.1127 0.4197 0.6072
Schistosoma mansoni intermediate filament proteins 0.0025 0.0039 0.0057
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.03 0.2624
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0039 0.0051
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.002 0.0146
Toxoplasma gondii DNA topoisomerase 2, putative 0.0139 0.0467 0.0905
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1846 0.6912 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0135 0.0452 0.0628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0006 0.0003
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0016 0.0004 0.0006
Leishmania major heat shock protein, putative 0.0162 0.0555 0.0803
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Trypanosoma cruzi cysteine protease, putative 0.0032 0.0063 0.0092
Mycobacterium ulcerans thioesterase 0.0017 0.0007 0.0033
Brugia malayi Serotonin receptor 0.0366 0.1325 0.1913
Onchocerca volvulus 0.0047 0.0119 0.0876
Mycobacterium ulcerans hypothetical protein 0.0126 0.042 0.3692
Echinococcus granulosus single minded 2 0.0134 0.045 0.0645
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0052 0.0138 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0139 0.0467 0.3311
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0063 0.018 0.0261
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0091 0.0126
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0095 0.0301 0.0336
Echinococcus multilocularis serotonin receptor 0.0366 0.1325 0.1322
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0184 0.0638 0.0917
Loa Loa (eye worm) hypothetical protein 0.011 0.0357 0.0511
Loa Loa (eye worm) fatty acid synthase 0.002 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium leprae conserved hypothetical protein 0.0135 0.0452 0.3968
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0068 0.0099
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0366 0.1325 0.1913
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0148 0.0214
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0139 0.0467 0.4106
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0245 0.087 0.1235
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0016 0.0004 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0063 0.0092
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0162 0.0554 0.4164
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0114 0.0374 0.0541
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Toxoplasma gondii cathepsin B 0.0063 0.018 0.0347
Brugia malayi neuropeptide F receptor 0.0366 0.1325 0.1913
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0184 0.064 0.9996
Schistosoma mansoni neuropeptide F-like receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0447
Brugia malayi AF-10 protein 0.0018 0.0011 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.0366 0.1325 0.1322
Brugia malayi hypothetical protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Probable two component sensor kinase 0.0139 0.0467 0.411
Loa Loa (eye worm) neuropeptide F receptor 0.0366 0.1325 0.1913
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0135 0.0452 0.0653
Trichomonas vaginalis porcupine, putative 0.0052 0.0138 0.0174
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.002 0.002 0.014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0238 0.084 0.0836
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0089 0.028 0.2452
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0135 0.0452 0.0628
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0027 0.0039
Leishmania major phosphatidylinositol kinase, putative 0.0135 0.0452 0.0653
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0068 0.0093
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0016 0.0004 0.0006
Trypanosoma cruzi Heat shock protein 83, putative 0.0453 0.1655 0.2394
Leishmania major cysteine peptidase A (CPA) 0.0057 0.0159 0.023
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Serotonin receptor 0.0366 0.1325 0.1913
Trypanosoma cruzi heat shock protein 90, putative 0.0291 0.1044 0.151
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0068 0.0099
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0295 0.1057 0.1507
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Loa Loa (eye worm) phosphatidylinositol kinase 0.0135 0.0452 0.0647
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0034 0.0071 0.0067
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Loa Loa (eye worm) prolyl oligopeptidase 0.0162 0.0554 0.0796
Onchocerca volvulus 0.0162 0.0554 0.416
Onchocerca volvulus 0.0366 0.1325 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus biogenic amine 5HT receptor 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0016 0.0004 0.0006
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0147 0.0497 0.0719
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Entamoeba histolytica vacuolar protein sorting 26 0.0052 0.0138 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Onchocerca volvulus 0.0366 0.1325 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0091 0.0126
Brugia malayi kinase, mitochondrial precursor 0.1127 0.4197 0.6069
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Loa Loa (eye worm) fibroinase 0.0057 0.0159 0.0224
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0016 0.0005 0.0014
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0456 0.1666 0.1662
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) PHD-finger family protein 0.0055 0.0151 0.0213
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0018 0.0011 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.1578 0.5902 0.8535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0034 0.0071 0.0097
Plasmodium vivax DNA topoisomerase II, putative 0.0139 0.0467 0.2784
Trichomonas vaginalis PIKK family atypical protein kinase 0.1204 0.4489 0.6485
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0139 0.0467 0.411
Trypanosoma brucei glycerol uptake protein, putative 0.0052 0.0138 0.02
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0139 0.0467 0.067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0129 0.0432 0.0619
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Brugia malayi Cathepsin L-like precursor 0.0057 0.0159 0.0224
Schistosoma mansoni fkbp-rapamycin associated protein 0.0362 0.1312 0.1898
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0076 0.0072
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0016 0.0004 0.0006
Loa Loa (eye worm) oxidoreductase 0.0037 0.0083 0.0115
Entamoeba histolytica protein kinase rad3, putative 0.0362 0.1312 0.1877
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0095 0.0301 0.0297
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0064 0.0536
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Trypanosoma cruzi DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Onchocerca volvulus 0.0139 0.0469 0.3518
Brugia malayi Matrixin family protein 0.0275 0.0984 0.1418
Echinococcus multilocularis heat shock protein 90 0.0453 0.1655 0.1651
Mycobacterium tuberculosis Polyketide synthase Pks13 0.003 0.0058 0.0481
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Toxoplasma gondii hypothetical protein 0.0061 0.0174 0.0335
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0084 0.0095
Schistosoma mansoni pyruvate dehydrogenase 0.0988 0.3673 0.5315
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus aryl hydrocarbon receptor 0.0046 0.0117 0.0163
Loa Loa (eye worm) latrophilin receptor protein 2 0.0042 0.0102 0.0141
Loa Loa (eye worm) hypothetical protein 0.0091 0.0285 0.0407
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0163 0.0559 0.1084
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Brugia malayi Calcitonin receptor-like protein seb-1 0.0132 0.0444 0.0636
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1312 0.1893
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0072
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0068 0.0064
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Leishmania major hypothetical protein, unknown function 0.0135 0.0452 0.0653
Schistosoma mansoni histamine h1 receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1127 0.4197 0.4194
Echinococcus granulosus G protein coupled receptor 139 0.0366 0.1325 0.1913
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0073 0.0218 0.029
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0225 0.0795 0.1144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0094 0.011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0162 0.0555 0.0778
Echinococcus multilocularis serine protein kinase ATM 0.0362 0.1312 0.1308
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0366 0.1325 0.1322
Plasmodium falciparum amino acid transporter, putative 0.0061 0.0174 0.0987
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0119 0.0173
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0063 0.018 0.0261
Toxoplasma gondii PHD-finger domain-containing protein 0.0055 0.0151 0.0291
Loa Loa (eye worm) transcription factor SMAD2 0.0205 0.0717 0.1032
Schistosoma mansoni zinc finger protein 0.0019 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0062 0.0177 0.0249
Trichomonas vaginalis heat shock protein, putative 0.0453 0.1655 0.2374
Plasmodium falciparum heat shock protein 90, putative 0.0162 0.0555 0.3306
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0016 0.0004 0.0006
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0083 0.0709
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium tuberculosis Conserved hypothetical protein 0.0135 0.0452 0.3972
Schistosoma mansoni single-minded 0.0176 0.0609 0.0881
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1846 0.6912 1
Loa Loa (eye worm) neuropeptide F receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0126 0.042 0.0602
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0215 0.0755 0.1093
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0075 0.0071
Echinococcus multilocularis expressed conserved protein 0.0041 0.0097 0.0093
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0083 0.0095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0083 0.0709
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0184 0.0638 0.0923
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0039 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis allatostatin A receptor 0.0366 0.1325 0.1322
Giardia lamblia Cathepsin B precursor 0.0063 0.018 0.016
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Trypanosoma cruzi heat shock protein, putative 0.0162 0.0555 0.0803
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Echinococcus multilocularis dro:myosuppressin receptor 0.0366 0.1325 0.1322
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0052 0.0138 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0071 0.0076
Loa Loa (eye worm) endoplasmin 0.0453 0.1655 0.239
Loa Loa (eye worm) TOPoisomerase family member 0.0139 0.0467 0.067
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Plasmodium vivax vivapain-1 0.0032 0.0063 0.0332
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Echinococcus granulosus lamin dm0 0.0025 0.0039 0.0051
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0102 0.0098
Plasmodium vivax amine transporter, putative 0.0061 0.0174 0.1002
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0042 0.0102 0.0141
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.036 0.1304 0.13
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0129 0.0432 0.0619
Trypanosoma brucei heat shock protein 90, putative 0.0453 0.1655 0.2394
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0238 0.084 0.121
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0184 0.064 0.0831
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Onchocerca volvulus 0.0366 0.1325 1
Brugia malayi prolyl oligopeptidase family protein 0.0162 0.0554 0.0796
Onchocerca volvulus Fatty acid synthase homolog 0.0036 0.0081 0.0588
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Schistosoma mansoni lamin 0.0025 0.0039 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0063 0.0066
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0184 0.0638 0.0917
Trichomonas vaginalis guanylate cyclase, putative 0.0046 0.0117 0.0142
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Schistosoma mansoni vesicular amine transporter 0.0017 0.0007 0.001
Leishmania major mitochondrial DNA topoisomerase II 0.0139 0.0467 0.0676
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0061 0.0174 0.017
Schistosoma mansoni opsin-like receptor 0.0366 0.1325 0.1918
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0188 0.0653 0.1267
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0366 0.1324 0.1916
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0103
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0139 0.0467 0.411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0452 0.0628
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0162 0.0555 0.0551
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0366 0.1325 0.1322
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Schistosoma mansoni apoptosis regulator bax 0.0061 0.0174 0.0251
Onchocerca volvulus 0.0366 0.1325 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0366 0.1325 0.1913
Schistosoma mansoni hypothetical protein 0.0476 0.1743 0.2521
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0083 0.0115
Echinococcus multilocularis PHD finger protein rhinoceros 0.0055 0.0151 0.0147
Loa Loa (eye worm) phosphatidylinositol 3 0.0135 0.0452 0.0647
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0148 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0061 0.0173 0.0245
Loa Loa (eye worm) hhat protein 0.0052 0.0138 0.0194
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0366 0.1325 0.1913
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0211 0.074 0.1065
Loa Loa (eye worm) hypothetical protein 0.0402 0.1461 0.2109
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0181 0.0628 0.3763
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0139 0.0467 0.0651
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0366 0.1325 0.1913
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.0719
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0034 0.0071 0.0362
Plasmodium falciparum heat shock protein 90, putative 0.0162 0.0555 0.3306
Leishmania major phosphatidylinositol kinase related protein, putative 0.0135 0.0452 0.0653
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0447
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0159 0.0155
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0068 0.0064
Brugia malayi Matrixin family protein 0.0114 0.0374 0.0535
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Leishmania major glycerol uptake protein, putative 0.0052 0.0138 0.02
Onchocerca volvulus 0.0366 0.1325 1
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0061 0.0173 0.0245
Echinococcus granulosus dro:myosuppressin receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0366 0.1325 0.1322
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0316 0.1136 0.1132
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0084 0.0095
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Mycobacterium tuberculosis Polyketide synthase Pks2 0.002 0.0018 0.0125
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Mycobacterium tuberculosis Possible two component sensor kinase 0.0139 0.0467 0.411
Trichomonas vaginalis heat shock protein, putative 0.0315 0.1131 0.1615
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Schistosoma mansoni P2X receptor subunit 0.125 0.4661 0.6743
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0025 0.0188
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0159 0.0224
Trypanosoma cruzi heat shock protein 90, putative 0.0453 0.1655 0.2394
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0052 0.0138 0.02
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0184 0.064 0.5639
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0083 0.0095
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0456 0.1666 0.241
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Echinococcus multilocularis peregrin 0.0057 0.016 0.0156
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0135 0.0452 0.0875
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0366 0.1325 0.1918
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0138 0.0174
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0151 0.0865
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.002 0.0018 0.0027
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0018 0.0011 0.0017
Onchocerca volvulus 0.0366 0.1325 1
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0181 0.0628 0.3753
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Giardia lamblia Grp94/Hsp90 0.0315 0.1131 0.155
Brugia malayi cathepsin L-like precursor 0.004 0.0094 0.013
Loa Loa (eye worm) melatonin receptor type 1A 0.0366 0.1325 0.1913
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0366 0.1325 0.1913
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0366 0.1325 0.1918
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0139 0.0467 0.411
Onchocerca volvulus 0.0366 0.1325 1
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Loa Loa (eye worm) hypothetical protein 0.0132 0.0444 0.0636
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0016 0.0004 0.0006
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0102 0.0141
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0119 0.0115
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Loa Loa (eye worm) TAR-binding protein 0.007 0.0206 0.0292
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0206 0.0292
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0432 0.0428
Onchocerca volvulus Tyrosine kinase homolog 0.0142 0.0481 0.3611
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0177 0.0255
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Echinococcus granulosus heat shock protein 90 0.0315 0.1131 0.1632
Schistosoma mansoni pyruvate dehydrogenase 0.0988 0.3673 0.5315
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0057 0.0159 0.0898
Onchocerca volvulus 0.0135 0.0452 0.3389
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.037 0.1341 0.194
Giardia lamblia Heat shock protein HSP 90-alpha 0.0315 0.1131 0.155
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0019 0.0021
Onchocerca volvulus 0.0052 0.0138 0.1019
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0164 0.0231
Brugia malayi AKH receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypoxia-induced factor 1 0.0545 0.2003 0.2893
Loa Loa (eye worm) hypothetical protein 0.0139 0.0467 0.067
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) matrix metalloproteinase 0.0114 0.0374 0.0535
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.037 0.1341 0.1919
Loa Loa (eye worm) hypothetical protein 0.0238 0.0843 0.1213
Brugia malayi Latrophilin receptor protein 2 0.0042 0.0102 0.0141
Echinococcus granulosus cathepsin L cysteine protease 0.0032 0.0063 0.0086
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0139 0.0467 0.411
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0181 0.0628 0.0885
Schistosoma mansoni neuropeptide f receptor 76f 0.0366 0.1325 0.1918
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0315 0.1131 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0111 0.0362 0.0524
Echinococcus multilocularis cysteine protease 0.0057 0.0159 0.0155
Brugia malayi Bromodomain containing protein 0.0057 0.016 0.0225
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0083 0.0709
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0061 0.0174 0.0245
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0011 0.0019
Brugia malayi Hhat protein 0.0052 0.0138 0.0194
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0519 0.0745
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0063 0.0092
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0256 0.0909 0.1292
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0362 0.1312 0.1308
Brugia malayi bHLH-PAS transcription factor 0.013 0.0436 0.0625
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Brugia malayi jmjC domain containing protein 0.0033 0.0068 0.0093
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0135 0.0452 0.0653
Schistosoma mansoni hypothetical protein 0.0267 0.0953 0.1379
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Toxoplasma gondii FATC domain-containing protein 0.0362 0.1312 0.2549
Schistosoma mansoni hypothetical protein 0.0476 0.1743 0.2521
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.037 0.1341 0.1919
Brugia malayi P38 map kinase family protein 2 0.0215 0.0755 0.1087
Onchocerca volvulus 0.0057 0.0159 0.1177
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Mycobacterium leprae Possible regulatory protein 0.0046 0.0117 0.0996
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0039 0.0051
Echinococcus multilocularis musashi 0.0025 0.0039 0.0035
Brugia malayi hypothetical protein 0.0061 0.0172 0.0243
Echinococcus granulosus cathepsin l1 0.004 0.0094 0.013
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii heat shock protein 90, putative 0.0453 0.1655 0.3216
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0366 0.1325 0.1918
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0004 0.0005
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0139 0.0467 0.411
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.002 0.0146
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0366 0.1325 0.1918
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0004 0.0006
Schistosoma mansoni sterol O-acyltransferase 1 0.029 0.1037 0.15
Schistosoma mansoni endoplasmin 0.0453 0.1655 0.2394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0046 0.0117 0.0163
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0052 0.0138 0.0266
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0114 0.0374 0.0535
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0039 0.0091 0.0777
Leishmania major developmentally regulated phosphoprotein-like protein 0.1127 0.4197 0.6072
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0445 0.1624 0.235
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0183 0.0636 0.0632
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0052 0.0138 0.0786
Trichomonas vaginalis DNA topoisomerase II, putative 0.0139 0.0467 0.0651
Echinococcus multilocularis serotonin receptor 0.0366 0.1325 0.1322
Onchocerca volvulus 0.0057 0.0159 0.1177
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0362 0.1312 0.1898
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0016 0.0004 0.0006
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0152 0.0519 0.0745
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Echinococcus multilocularis cysteine protease 0.0057 0.0159 0.0155
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Trichomonas vaginalis receptor histidine kinase, putative 0.0139 0.0467 0.0651
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0042 0.0102 0.0098
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) phosphatidylinositol 3 0.063 0.2322 0.3355
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0267 0.0953 0.1357
Schistosoma mansoni heat shock protein 0.0453 0.1655 0.2394
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Trichomonas vaginalis transmembrane protein nessy, putative 0.0052 0.0138 0.0174
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Brugia malayi Bromodomain containing protein 0.0037 0.0085 0.0116
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Plasmodium falciparum endoplasmin, putative 0.0301 0.1078 0.6491
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0063 0.0092
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Trypanosoma brucei Heat shock protein 83, putative 0.0453 0.1655 0.2394
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0163 0.0559 0.0803
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0052 0.0138 0.0771
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0083 0.0159
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.1127 0.4197 0.6072
Echinococcus granulosus rhodopsin orphan GPCR 0.0366 0.1325 0.1913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Onchocerca volvulus 0.0057 0.0159 0.1177
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0057 0.0159 0.0898
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0366 0.1325 0.1913
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0015 0.0002 0.0002
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1846 0.6912 1
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Entamoeba histolytica hypothetical protein 0.0061 0.0172 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.1099 0.4092 0.5909
Echinococcus multilocularis transfer RNA-Lys 0.013 0.0436 0.0432
Schistosoma mansoni cathepsin s 0.0017 0.0009 0.0013
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0062 0.0177 0.0249
Onchocerca volvulus 0.0366 0.1325 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0063 0.0092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0225 0.0795 0.1144
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0052 0.0138 0.0194
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0135 0.0452 0.0628
Trypanosoma cruzi heat shock protein 90, putative 0.0315 0.1131 0.1637
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0144 0.0202
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0366 0.1325 0.1322
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.017 0.0587 0.0849
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0315 0.1131 0.3196
Echinococcus multilocularis somatostatin receptor 0.0366 0.1325 0.1322
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0061 0.0174 0.017
Trypanosoma cruzi heat shock protein 85, putative 0.0315 0.1131 0.1637
Leishmania major hypothetical protein, conserved 0.0135 0.0452 0.0653
Brugia malayi Cathepsin L-like precursor 0.004 0.0094 0.013
Onchocerca volvulus 0.0057 0.0159 0.1177
Entamoeba histolytica cysteine protease, putative 0.0057 0.0159 0.0204
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0315 0.1131 0.1637
Echinococcus multilocularis g-protein coupled receptor 0.0366 0.1325 0.1322
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0139 0.0467 0.0651
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0016 0.0004 0.0006
Brugia malayi cathepsin B-like cysteine proteinase 0.017 0.0587 0.0843
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Echinococcus granulosus o acyltransferase membrane bound domain 0.0052 0.0138 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Schistosoma mansoni lamin 0.0025 0.0039 0.0057
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1846 0.6912 1
Onchocerca volvulus 0.0366 0.1325 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0028 0.005 0.0045
Schistosoma mansoni sodium-dependent amino acid transporter 0.0061 0.0174 0.0251
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1846 0.6912 1
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni hypothetical protein 0.0052 0.0138 0.02
Echinococcus multilocularis mitogen activated protein kinase 14 0.0215 0.0755 0.0751
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0215 0.0755 0.1093
Entamoeba histolytica acyl-coA synthetase, putative 0.0126 0.042 0.0583
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0366 0.1325 0.1918
Echinococcus multilocularis mitogen activated protein kinase 11 0.0215 0.0755 0.0751
Echinococcus granulosus intermediate filament protein 0.0025 0.0039 0.0051
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0004 0.0005
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0139 0.0467 0.3507
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0016 0.0004 0.0006
Loa Loa (eye worm) apoptosis regulator protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans thioesterase TesA 0.0017 0.0007 0.0033
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Leishmania major DNA topoisomerase ii 0.0139 0.0467 0.0676
Echinococcus multilocularis cathepsin b 0.017 0.0587 0.0583
Echinococcus granulosus lamin 0.0025 0.0039 0.0051
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0135 0.0452 0.0447
Trypanosoma cruzi GUP1, putative 0.0052 0.0138 0.02
Leishmania major protein kinase, putative 0.0047 0.012 0.0173
Loa Loa (eye worm) ctsf protein 0.0057 0.0159 0.0224
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0267 0.0953 0.1374
Echinococcus granulosus peptide allatostatin:somatostatin 0.0366 0.1325 0.1913
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0083 0.0121
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Plasmodium falciparum transporter, putative 0.0061 0.0174 0.0987
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0063 0.0066
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0414 0.1508 0.1504
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0045
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0139 0.0467 0.0676
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Brugia malayi hypothetical protein 0.013 0.0434 0.0622
Loa Loa (eye worm) hypothetical protein 0.029 0.1037 0.1495
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0184 0.064 0.1241
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0016 0.0004 0.0006
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0004 0.0006
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0061 0.0174 0.0245
Loa Loa (eye worm) hypothetical protein 0.0094 0.03 0.0427
Leishmania major hypothetical protein, conserved 0.0139 0.0467 0.0676
Echinococcus multilocularis cathepsin b 0.017 0.0587 0.0583
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0139 0.0467 0.411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Toxoplasma gondii type I fatty acid synthase, putative 0.0027 0.0044 0.0083
Brugia malayi neuropeptide F receptor 0.0366 0.1325 0.1913
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1127 0.4197 0.4194
Echinococcus granulosus sterol O acyltransferase 1 0.029 0.1037 0.1495
Echinococcus granulosus neuropeptide receptor A26 0.0366 0.1325 0.1913
Entamoeba histolytica hypothetical protein 0.0135 0.0452 0.0628
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0456 0.1666 0.2405
Onchocerca volvulus 0.0057 0.0159 0.1177
Schistosoma mansoni hypothetical protein 0.0041 0.0097 0.0141
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0776 0.2874 0.4159
Onchocerca volvulus 0.013 0.0436 0.3272
Mycobacterium leprae Probable two component sensor kinase MprB 0.0139 0.0467 0.4106
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0159 0.0155
Toxoplasma gondii target of rapamycin (TOR), putative 0.1377 0.5142 1
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0119 0.0173
Leishmania major 4-coumarate:coa ligase-like protein 0.0126 0.042 0.0608
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0419 0.0606
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.0051
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0083 0.0453
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0162 0.0555 0.0778
Loa Loa (eye worm) phosphatidylinositol 3 0.1846 0.6912 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0139 0.0467 0.411
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0083 0.0709
Brugia malayi Dopamine receptor protein 1 0.0366 0.1325 0.1913
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0083 0.0095
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0095 0.0301 0.0297
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0063 0.0086
Mycobacterium leprae Probable two-component sensor kinase 0.0139 0.0467 0.4106
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.005 0.0248
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0052 0.0138 0.0194
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0016 0.0004 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0046 0.0117 0.0142
Brugia malayi sulfakinin receptor protein 0.0366 0.1325 0.1913
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Plasmodium falciparum phd finger protein, putative 0.0055 0.0151 0.085
Onchocerca volvulus 0.0061 0.0174 0.1287
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0366 0.1325 0.1322
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0043 0.0107 0.0148
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0042 0.0102 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.063 0.2322 0.2319
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0139 0.0467 0.3507
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Schistosoma mansoni pyruvate dehydrogenase 0.1127 0.4197 0.6072
Loa Loa (eye worm) hypothetical protein 0.0042 0.0101 0.014
Echinococcus multilocularis tar DNA binding protein 0.007 0.0206 0.0202
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0184 0.0638 0.0917
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0148 0.128
Echinococcus granulosus endoplasmin 0.0315 0.1131 0.1632
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0052 0.0138 0.0134
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0039 0.0091 0.0777
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0163 0.0559 0.0809
Brugia malayi AMP-binding enzyme family protein 0.0126 0.042 0.0602
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0147 0.0497 0.2955
Echinococcus multilocularis neuropeptide receptor A26 0.0366 0.1325 0.1322
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.003 0.0058 0.0481
Plasmodium vivax hypothetical protein, conserved 0.0139 0.0467 0.2784
Schistosoma mansoni hypothetical protein 0.0283 0.1012 0.1464
Echinococcus multilocularis serotonin transporter 0.0165 0.0565 0.0561
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Entamoeba histolytica cysteine proteinase 2 0.0032 0.0063 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0068 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0016 0.0004 0.0006
Brugia malayi Probable DNA topoisomerase II 0.0139 0.0467 0.067
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1846 0.6912 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0362 0.1312 0.1893
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0028 0.005 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1846 0.6912 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0184 0.0638 0.0923
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0034 0.0071 0.0103
Onchocerca volvulus 0.0056 0.0155 0.1145
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0132 0.0444 0.0636
Loa Loa (eye worm) hypothetical protein 0.0047 0.0119 0.0167
Onchocerca volvulus 0.0046 0.0117 0.0855
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0042 0.0102 0.0141
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0034 0.0071 0.0097
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis lamin 0.0025 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0039 0.0091 0.0771
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.002 0.002 0.0023
Mycobacterium ulcerans polyketide synthase 0.0021 0.0025 0.0188
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0228 0.0804 0.1164
Onchocerca volvulus Neuropeptide F receptor homolog 0.0366 0.1325 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.013
Echinococcus multilocularis geminin 0.0476 0.1743 0.1739
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0063 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.1099 0.4092 0.5909
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0147 0.0497 0.2966
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0184 0.0638 0.0899
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.3729 0.5383
Trichomonas vaginalis PIKK family atypical protein kinase 0.1472 0.5499 0.795
Echinococcus granulosus g protein coupled receptor 0.0366 0.1325 0.1913
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0063 0.018 0.0235
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0017 0.0007 0.0027
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0021 0.0025 0.0188
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0054 0.0149 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0071 0.0103
Loa Loa (eye worm) hhat protein 0.0052 0.0138 0.0194
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0061 0.0173 0.0245
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0215 0.0755 0.1087
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.002 0.0146
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.002 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0117 0.0142
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0061 0.0174 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0116 0.0167
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0135 0.0452 0.0647
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0095 0.0301 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0159 0.0204
Toxoplasma gondii heat shock protein 75, putative 0.0162 0.0555 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Chlamydia trachomatis DNA gyrase subunit B 0.0139 0.0467 0.6291
Echinococcus multilocularis G-protein coupled receptor, putative 0.0366 0.1325 0.1322
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0162 0.0554 0.0796
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0043 0.0107 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0129 0.0432 0.0619
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0183 0.0636 0.0915
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0054 0.0149 0.0145
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.063 0.2322 0.3359
Echinococcus multilocularis cathepsin L 0.0032 0.0063 0.0059
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0009 0.0013
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0034 0.0071 0.0097
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0063 0.0092
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0174 0.0251
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0139 0.0468 0.4113
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0004 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0083 0.0709
Loa Loa (eye worm) hypothetical protein 0.0042 0.01 0.0139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0132 0.0444 0.0636
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Entamoeba histolytica hypothetical protein 0.0073 0.0218 0.029
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0366 0.1325 0.1322
Echinococcus granulosus cysteine protease 0.0032 0.0063 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0138 0.0174
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0095 0.0301 0.0429
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus granulosus sodium and chloride dependent glycine 0.0225 0.0795 0.1144
Trichomonas vaginalis conserved hypothetical protein 0.0402 0.1461 0.2093
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0034 0.0071 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0126 0.042 0.3692
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0068 0.0093
Mycobacterium leprae Polyketide synthase Pks13 0.003 0.0058 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.111 0.4133 0.5968
Trypanosoma brucei heat shock protein, putative 0.0453 0.1655 0.2394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Chlamydia trachomatis DNA gyrase subunit B 0.0139 0.0467 0.6291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Echinococcus multilocularis p2X purinoceptor 4 0.125 0.4661 0.4659
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0083 0.0121
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0063 0.0086
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0366 0.1325 0.1913
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0144 0.0139
Trypanosoma cruzi GUP1, putative 0.0052 0.0138 0.02
Brugia malayi mbt repeat family protein 0.0047 0.0119 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Echinococcus granulosus heat shock protein 90 0.0453 0.1655 0.239
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.037 0.1341 0.1919
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0016 0.0004 0.0006
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Giardia lamblia GTOR 0.1846 0.6912 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0129 0.0432 0.0428
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0362
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Brugia malayi MBOAT family protein 0.0052 0.0138 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.063 0.2322 0.3342
Brugia malayi prolyl oligopeptidase family protein 0.0054 0.0149 0.0209
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0039 0.0091 0.0777
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0054 0.0149 0.0215
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0046 0.0117 0.0112
Schistosoma mansoni hypothetical protein 0.0042 0.0102 0.0147
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0016 0.0004 0.0006
Plasmodium vivax hypothetical protein 0.0135 0.0452 0.2689
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0139 0.0467 0.0676
Mycobacterium ulcerans two component sensor kinase MprB 0.0139 0.0467 0.411
Mycobacterium ulcerans putative regultory protein 0.0139 0.0467 0.411
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0184 0.0638 0.0634
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.002 0.0018 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0068 0.0099
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0445 0.1624 0.2345
Echinococcus granulosus somatostatin receptor 0.0366 0.1325 0.1913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0366 0.1325 0.1913
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0039 0.0091 0.0777
Brugia malayi Bromodomain containing protein 0.0073 0.022 0.0312
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0046 0.0117 0.0169
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.002 0.0018 0.002
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0061 0.0174 0.0245
Schistosoma mansoni alpha-1 adrenergic receptor 0.0366 0.1325 0.1918
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0159 0.0224
Brugia malayi Hemopexin family protein 0.0162 0.0554 0.0795
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0052 0.0138 0.0194
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0027 0.0032
Schistosoma mansoni hypothetical protein 0.0018 0.0011 0.0017
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0689 0.2546 1
Onchocerca volvulus Cathepsin F homolog 0.0057 0.0159 0.1177
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0083 0.0709
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0004 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Schistosoma mansoni biogenic amine (5HT) receptor 0.0366 0.1325 0.1918
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0135 0.0452 0.0653
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus zinc finger protein 0.0019 0.0016 0.0017
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Plasmodium vivax acyl-CoA synthetase, putative 0.0094 0.03 0.1766
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0016 0.0004 0.0006
Schistosoma mansoni biogenic amine receptor 0.0366 0.1325 0.1918
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0126 0.042 0.3692
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0042 0.0102 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0016 0.0004 0.0006
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0068 0.013
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0086 0.0268 0.0382
Brugia malayi Melatonin receptor type 1A 0.0366 0.1325 0.1913
Echinococcus granulosus p2X purinoceptor 4 0.125 0.4661 0.6741
Loa Loa (eye worm) MBOAT family protein 0.0052 0.0138 0.0194
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0285 0.102 0.1453
Brugia malayi ORL1-like opioid receptor 0.0366 0.1325 0.1913
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Loa Loa (eye worm) PHD-finger family protein 0.002 0.002 0.0022
Schistosoma mansoni heat shock protein 0.0453 0.1655 0.2394
Toxoplasma gondii hypothetical protein 0.0061 0.0174 0.0335
Plasmodium vivax heat shock protein, putative 0.0162 0.0555 0.3317
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1846 0.6912 0.6911
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0126 0.042 0.3692
Onchocerca volvulus 0.0025 0.0039 0.0271
Brugia malayi PHD-finger family protein 0.0024 0.0035 0.0045
Loa Loa (eye worm) hypothetical protein 0.0373 0.1351 0.195
Echinococcus granulosus GPCR family 2 0.0042 0.0102 0.0141
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.063 0.2322 0.3359
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.005 0.0045
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0016 0.0004 0.0006
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0184 0.064 0.5642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trichomonas vaginalis heat shock protein, putative 0.0301 0.1078 0.1538
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0016 0.0004 0.0006
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Echinococcus granulosus alpha 1A adrenergic receptor 0.0366 0.1325 0.1913
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Leishmania major cathepsin L-like protease 0.0057 0.0159 0.023
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Echinococcus granulosus Dipeptidyl peptidase 9 0.0054 0.0149 0.0209
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0366 0.1325 0.1918
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0135 0.0452 0.2678
Echinococcus multilocularis endoplasmin 0.0315 0.1131 0.1128
Onchocerca volvulus Alhambra homolog 0.0055 0.0151 0.1117
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0028 0.005 0.0072
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0162 0.0554 0.055
Echinococcus multilocularis sex peptide receptor 0.0366 0.1325 0.1322
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.012 0.0173
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0139 0.0467 0.411
Echinococcus multilocularis G protein coupled receptor 139 0.0366 0.1325 0.1322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0159 0.023
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.004 0.0094 0.0136
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1846 0.6912 1
Echinococcus granulosus serotonin transporter 0.0165 0.0565 0.0812
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus multilocularis lamin dm0 0.0025 0.0039 0.0035
Schistosoma mansoni amine GPCR 0.0366 0.1325 0.1918
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus granulosus mitogen activated protein kinase 11 0.0215 0.0755 0.1087
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0052 0.0138 0.02
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Schistosoma mansoni hypothetical protein 0.0061 0.0172 0.0249
Plasmodium vivax vivapain-2 0.0057 0.0159 0.0913
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0055 0.0151 0.0219
Onchocerca volvulus Matrix metalloproteinase homolog 0.0253 0.0898 0.6764
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0163 0.0559 0.3343
Trichomonas vaginalis PIKK family atypical protein kinase 0.1377 0.5142 0.7433
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0377
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0135 0.0452 0.2689
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0052 0.0138 0.0174
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0068 0.0064
Plasmodium falciparum enoyl-acyl carrier reductase 0.0184 0.064 0.3824
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0159 0.1177
Loa Loa (eye worm) hypothetical protein 0.0362 0.1312 0.1893
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Brugia malayi heat shock protein 90 0.0453 0.1655 0.239
Echinococcus multilocularis 0.0147 0.0497 0.0493
Echinococcus multilocularis sterol O acyltransferase 1 0.029 0.1037 0.1033
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0148 0.128
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0076
Brugia malayi hypothetical protein 0.0366 0.1325 0.1913
Brugia malayi AMP-binding enzyme family protein 0.0056 0.0155 0.0218
Echinococcus granulosus sex peptide receptor 0.0366 0.1325 0.1913
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0034 0.0071 0.0103
Schistosoma mansoni neuropeptide F-like receptor 0.0366 0.1325 0.1918
Leishmania major eukaryotic translation initiation factor-like protein 0.002 0.0018 0.0027
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0028 0.005 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0071 0.0135
Echinococcus multilocularis neuropeptide receptor 0.0366 0.1325 0.1322
Leishmania major cytochrome p450-like protein 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0139 0.0467 0.411
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0162 0.0555 0.417
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0159 0.0204
Echinococcus granulosus 7tm_1 domain containing protein 0.0366 0.1325 0.1913
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0366 0.1325 0.1322
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0139 0.0467 0.0651
Trichomonas vaginalis sensor histidine kinase, putative 0.0139 0.0467 0.0651
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.074 0.1047
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0059 0.0167 0.0163
Brugia malayi mbt repeat family protein 0.0047 0.0119 0.0167
Schistosoma mansoni sodium/chloride dependent transporter 0.0225 0.0795 0.115
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0094 0.011
Echinococcus granulosus jumonji domain containing protein 0.0077 0.0233 0.033
Echinococcus multilocularis mitogen activated protein kinase 14 0.0215 0.0755 0.0751
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.0419 0.06
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0034 0.0071 0.0103
Brugia malayi diacylglycerol acyltransferase 0.0052 0.0138 0.0194
Plasmodium vivax phosphodiesterase gamma, putative 0.0034 0.0071 0.0377
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0236 0.0833 0.1182
Echinococcus granulosus sodium and chloride dependent glycine 0.0225 0.0795 0.1144
Echinococcus granulosus tm gpcr rhodopsin 0.0366 0.1325 0.1913
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0061 0.0174 0.0245
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0119 0.0167
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0126 0.042 0.3688
Onchocerca volvulus 0.0114 0.0374 0.28
Onchocerca volvulus 0.0165 0.0565 0.4249
Leishmania major hypothetical protein, conserved 0.0052 0.0138 0.02
Loa Loa (eye worm) cysteine protease 0.0057 0.0159 0.0224
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0011 0.0016
Echinococcus multilocularis Zinc finger, PHD finger 0.0181 0.0628 0.0624
Brugia malayi PAS domain containing protein 0.0176 0.0609 0.0875
Echinococcus multilocularis jumonji domain containing protein 0.0077 0.0233 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.1004 0.3735 0.5391
Leishmania major pteridine reductase 1 0.0016 0.0004 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0366 0.1325 0.1322
Giardia lamblia PHD finger protein 15 0.0055 0.0151 0.0117
Brugia malayi hypothetical protein 0.0591 0.2176 0.3144
Echinococcus granulosus tachykinin peptides receptor 99D 0.0546 0.2004 0.2895
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0054 0.0149 0.0286
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0039 0.0091 0.0777
Plasmodium falciparum phosphodiesterase delta, putative 0.0034 0.0071 0.0362
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0099 0.0319 0.0617
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0032 0.0063 0.0092
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0021 0.0025 0.0182
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0016 0.0004 0.0006
Onchocerca volvulus 0.0366 0.1325 1
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0094 0.0299 0.0433
Loa Loa (eye worm) MH2 domain-containing protein 0.0205 0.0717 0.1032
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0159 0.023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0174 0.0245
Leishmania major cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0138 0.0466 0.065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0366 0.1325 0.1322
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0061 0.0174 0.0251
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0083 0.0709
Trichomonas vaginalis guanylate cyclase, putative 0.0046 0.0117 0.0142
Schistosoma mansoni hypothetical protein 0.0061 0.0174 0.0251
Schistosoma mansoni sodium/chloride dependent transporter 0.0226 0.0798 0.1154
Brugia malayi translation initiation factor 4E 0.002 0.0018 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1846 0.6912 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0366 0.1325 0.1918
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0097
Onchocerca volvulus 0.0025 0.0039 0.0271
Schistosoma mansoni hypothetical protein 0.0366 0.1325 0.1918
Entamoeba histolytica cysteine protease, putative 0.0032 0.0063 0.0066
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0159 0.0155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0048
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0068 0.0064
Schistosoma mansoni hypothetical protein 0.0091 0.0285 0.0413
Loa Loa (eye worm) hypothetical protein 0.0165 0.0565 0.0812
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0102 0.0141
Entamoeba histolytica hypothetical protein 0.0306 0.1099 0.1568
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0034 0.0071 0.0076
Toxoplasma gondii Hsp90 domain-containing protein 0.0162 0.0555 0.1076
Loa Loa (eye worm) hypothetical protein 0.0052 0.0138 0.0194
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1846 0.6912 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0034 0.0071 0.0076
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0061 0.0174 0.0251
Loa Loa (eye worm) hypothetical protein 0.0095 0.0301 0.0429
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0061 0.0174 0.0245
Leishmania major heat shock protein 83-1 0.0453 0.1655 0.2394
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0068 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0159 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0129 0.0432 0.0625
Echinococcus granulosus PHD finger protein rhinoceros 0.0055 0.0151 0.0213
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0009 0.0007
Echinococcus multilocularis aryl hydrocarbon receptor 0.0046 0.0117 0.0112
Echinococcus multilocularis potassium voltage gated channel protein 0.0062 0.0177 0.0172
Loa Loa (eye worm) hypothetical protein 0.0366 0.1325 0.1913
Echinococcus granulosus cathepsin b 0.017 0.0587 0.0843
Schistosoma mansoni DNA topoisomerase II 0.0139 0.0467 0.0676
Giardia lamblia Hypothetical protein 0.0135 0.0452 0.0556
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0028 0.005 0.0045
Schistosoma mansoni tar DNA-binding protein 0.007 0.0206 0.0299
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0306 0.1099 0.1568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1312 0.1877
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0245 0.087 0.1235
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0139 0.0467 0.411
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0009 0.0007
Brugia malayi Cathepsin L-like precursor 0.004 0.0094 0.013
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.0129
Schistosoma mansoni neuropeptide receptor 0.0366 0.1325 0.1918

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.32 uM Inhibition of HIF1 in human HEK293T cells transfected with pGL3-5HRE-VEGF and pRL-SV40 after 24 hrs by dual luciferase reporter assay ChEMBL. 26394152
Inhibition (binding) Inhibition of of HIF-1 alpha in human HEK293T cells under hypoxic condition at 1 uM after 24 hrs by Western blot analysis ChEMBL. 26394152
Inhibition (binding) Inhibition of HIF1alpha in human HEK293T cells assessed as decrease of Cdk6 expression under hypoxic condition at 1 uM after 24 hrs by Western blot analysis ChEMBL. 26394152
Inhibition (binding) Inhibition of HIF1beta in HEK293T cells under hypoxic condition at 1 uM after 24 hrs by Western blot analysis ChEMBL. 26394152
Inhibition (binding) Inhibition of HIF1alpha in human HEK293T cells assessed as decrease of VEGF mRNA expression under hypoxic condition at 1 uM after 24 hrs by RT-PCR analysis ChEMBL. 26394152
Inhibition (binding) = 113 % Inhibition of HIF1 in human HEK293T cells transfected with pGL3-5HRE-VEGF and pRL-SV40 after 24 hrs by dual luciferase reporter assay relative to normoxic condition ChEMBL. 26394152
Survival (ADMET) > 80 % Cytotoxicity against human HEK293T cells assessed as survival rate at 10 uM after 24 hrs by MTT assay ChEMBL. 26394152

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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