Detailed information for compound 1860817

Basic information

Technical information
  • TDR Targets ID: 1860817
  • Name: 4-(1-methylpiperidin-4-yl)-1-tridecylpiperidi ne dihydrochloride
  • MW: 437.573 | Formula: C24H50Cl2N2
  • H donors: 0 H acceptors: 0 LogP: 9.52 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCN1CCC(CC1)C1CCN(CC1)C.Cl.Cl
  • InChi: 1S/C24H48N2.2ClH/c1-3-4-5-6-7-8-9-10-11-12-13-18-26-21-16-24(17-22-26)23-14-19-25(2)20-15-23;;/h23-24H,3-22H2,1-2H3;2*1H
  • InChiKey: MMGPTGGGKSOPOA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(1-methyl-4-piperidyl)-1-tridecyl-piperidine dihydrochloride
  • 4-(1-methyl-4-piperidinyl)-1-tridecylpiperidine dihydrochloride
  • 4-(1-methylpiperidin-4-yl)-1-tridecyl-piperidine dihydrochloride

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Starlite/ChEMBL References
Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus granulosus guanine nucleotide binding protein G protein Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain Get druggable targets OG5_126802 All targets in OG5_126802
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus multilocularis guanine nucleotide binding protein (G protein) Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum Guanine nucleotide-binding protein G(i) subunit alpha, putative Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) heterotrimeric G protein alpha subunit Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum Guanine nucleotide-binding protein G(i) subunit alpha, putative Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus granulosus guanine nucleotide binding protein G protein Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma mansoni trimeric G-protein alpha o subunit Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 Get druggable targets OG5_126802 All targets in OG5_126802
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus granulosus gtp binding protein I alpha 1subunit Get druggable targets OG5_126802 All targets in OG5_126802
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit Get druggable targets OG5_126802 All targets in OG5_126802
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative Get druggable targets OG5_126802 All targets in OG5_126802
Candida albicans similar to G-alpha protein, glucose-induced activation of plasma membrane ATPase Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum Guanine nucleotide-binding protein G(i) subunit alpha, putative Get druggable targets OG5_126802 All targets in OG5_126802
Candida albicans similar to G-alpha protein, glucose-induced activation of plasma membrane ATPase Get druggable targets OG5_126802 All targets in OG5_126802
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126802 All targets in OG5_126802
Candida albicans G-protein alpha subunit capable of functional substitution for S. cerevisiae GPA1 (YHR005C) component of pheromone response path Get druggable targets OG5_126802 All targets in OG5_126802
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 Get druggable targets OG5_126802 All targets in OG5_126802
Candida albicans likely G-protein alpha subunit capable of functional substitution for S. cerevisiae GPA1 (YHR005C) component of pheromone respon Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum ko:K04534 guanine nucleotide binding protein (G protein), alpha o polypeptide, putative Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum Guanine nucleotide-binding protein G(i) subunit alpha-1, putative Get druggable targets OG5_126802 All targets in OG5_126802
Entamoeba histolytica G protein alpha subunit, putative Get druggable targets OG5_126802 All targets in OG5_126802
Echinococcus multilocularis guanine nucleotide binding protein (G protein) Get druggable targets OG5_126802 All targets in OG5_126802
Schistosoma japonicum Guanine nucleotide-binding protein G(i) subunit alpha, putative Get druggable targets OG5_126802 All targets in OG5_126802
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative Get druggable targets OG5_126802 All targets in OG5_126802
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative Get druggable targets OG5_126802 All targets in OG5_126802
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 354 aa 356 aa 50.6 %
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 354 aa 355 aa 54.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei trans-sialidase, putative 0.0092 0.0085 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.002 0.0006 0.0046
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0062 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.1451 0.1555 0.4459
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0108 0.0101 0.0326
Schistosoma mansoni hypothetical protein 0.0081 0.0073 0.021
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0736
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) cytochrome P450 family protein 0.0116 0.0111 0.0185
Loa Loa (eye worm) raf kinase 0.0252 0.0258 0.0433
Echinococcus granulosus cathepsin l1 0.0015 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0534 0.0563 0.0628
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0024
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0025 0.0028
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0075 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0012
Schistosoma mansoni myst-related protein 0.0016 0.0002 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Brugia malayi hypothetical protein 0.0054 0.0044 0.0073
Loa Loa (eye worm) matrixin family protein 0.5063 0.5463 0.9171
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0005 0.0006
Schistosoma mansoni nuclear receptor nhr-48 0.0084 0.0076 0.0219
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0005 0.0015
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.01 0.0093 0.0093
Brugia malayi Matrixin family protein 0.552 0.5956 1
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Trypanosoma cruzi cytochrome P450, putative 0.0116 0.0111 0.1086
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0012 0.0013
Onchocerca volvulus 0.0117 0.0112 0.0205
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0034 0.0022 0.0025
Onchocerca volvulus 0.0034 0.0022 0.0041
Echinococcus granulosus sex peptide receptor 0.0034 0.0022 0.0025
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0034 0.0022 0.0064
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0004 0.0004
Echinococcus granulosus G protein coupled receptor 139 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0104 0.0097 0.0163
Loa Loa (eye worm) hypothetical protein 0.0088 0.008 0.0134
Brugia malayi PAS domain containing protein 0.0047 0.0036 0.006
Trichomonas vaginalis importin beta-1, putative 0.0023 0.001 0.1247
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0008
Echinococcus granulosus intermediate filament protein 0.0026 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0499 0.0525 0.1506
Echinococcus multilocularis snurportin 1 0.0307 0.0317 0.0354
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0007 0.0058
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0117 0.0112 0.0321
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0027 0.2384
Brugia malayi Matrixin family protein 0.2283 0.2455 0.4121
Echinococcus multilocularis epidermal growth factor receptor 0.0468 0.0491 0.0548
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0076 0.0085
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0081 0.0073 0.9106
Loa Loa (eye worm) hypothetical protein 0.2283 0.2455 0.4121
Schistosoma mansoni biogenic amine receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.046 0.0482 0.081
Brugia malayi hypothetical protein 0.0054 0.0044 0.0073
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0037 0.0025 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0064
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Mycobacterium leprae putative cytochrome p450 0.0108 0.0101 0.0315
Loa Loa (eye worm) acetylcholine receptor protein 0.0054 0.0044 0.0073
Brugia malayi RNA, U transporter 1 0.0082 0.0074 0.0123
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0014 0.0001 0.0001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0005 0.0035
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0012 0.0026
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0014 0.0264
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0041 0.0069
Echinococcus multilocularis allatostatin A receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0179 0.0179 0.0199
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0054 0.0091
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0007 0.0008
Mycobacterium ulcerans hydrolase 0.2781 0.2993 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0006 0.0257
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0015 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0179 0.0179 0.03
Schistosoma mansoni amine GPCR 0.0034 0.0022 0.0064
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0007 0.0008
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Leishmania major cathepsin L-like protease 0.0073 0.0064 0.0622
Echinococcus multilocularis expressed conserved protein 0.0185 0.0185 0.0207
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Echinococcus multilocularis carbonic anhydrase 0.046 0.0482 0.0538
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Echinococcus granulosus dro:myosuppressin receptor 0.0034 0.0022 0.0025
Echinococcus granulosus 7tm_1 domain containing protein 0.0034 0.0022 0.0025
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0108 0.0101 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Onchocerca volvulus 0.0039 0.0027 0.0049
Echinococcus multilocularis dro:myosuppressin receptor 0.0034 0.0022 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0015 0.0693
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0037 0.0025 0.0231
Schistosoma mansoni nuclear receptor 0.0084 0.0076 0.0219
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0029 0.0033
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0054 0.2684
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0942 0.1004 0.2879
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0034 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0054
Loa Loa (eye worm) melatonin receptor type 1A 0.0034 0.0022 0.0037
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0075 0.0084
Schistosoma mansoni growth hormone secretagogue receptor 0.0034 0.0022 0.0064
Brugia malayi hypothetical protein 0.0084 0.0076 0.0128
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0093 0.0155
Brugia malayi PHD-finger family protein 0.0027 0.0015 0.0025
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0117 0.0112 0.0188
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0022 0.0037
Schistosoma mansoni tyrosine kinase 0.0247 0.0252 0.0723
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1091 0.1165 0.3884
Loa Loa (eye worm) hypothetical protein 0.046 0.0482 0.081
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0061 0.3052
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0004 0.0021
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0007 0.0879
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0179 0.0179 0.0512
Loa Loa (eye worm) hypothetical protein 0.046 0.0482 0.081
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0179 0.0179 0.03
Onchocerca volvulus 0.0037 0.0025 0.0045
Schistosoma mansoni myosin xvIII 0.0034 0.0022 0.0064
Onchocerca volvulus 4.1 G protein, putative homolog 0.0037 0.0025 0.0045
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0053 0.0089
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0006 0.0008
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0054 0.0044 0.0048
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.2781 0.2993 1
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Echinococcus multilocularis orexin receptor type 2 0.0034 0.0022 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0021
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0037 0.0025 0.0028
Echinococcus granulosus carbonic anhydrase 0.046 0.0482 0.0538
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0016 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Onchocerca volvulus 0.007 0.0061 0.0112
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) GABA receptor subunit 0.0063 0.0053 0.0089
Echinococcus granulosus epidermal growth factor receptor 0.0253 0.0259 0.0289
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0008 0.0009
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0018
Echinococcus granulosus g protein coupled receptor 0.0034 0.0022 0.0025
Echinococcus granulosus g-protein coupled receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0061 0.0192
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0022 0.0008 0.1009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0034 0.0022 0.0064
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0039 0.0044
Echinococcus granulosus FTZ F1 alpha 0.0179 0.0179 0.0199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0117 0.0112 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0179 0.0179 0.03
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0007 0.0012
Brugia malayi nuclear hormone receptor family member odr-7 0.0084 0.0076 0.0128
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.001 0.0086
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0007 0.0058
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0048 0.0037 0.0105
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium ulcerans monoamine oxidase 0.0083 0.0074 0.0236
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0149 0.0146 0.0245
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0037 0.0025 0.0071
Loa Loa (eye worm) beta-lactamase 0.0038 0.0026 0.0044
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.1247
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0022 0.0008 0.0014
Schistosoma mansoni patched 1 0.0085 0.0077 0.0219
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.001 0.001
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0016 0.0018
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.2781 0.2993 0.5025
Echinococcus multilocularis 0.0083 0.0074 0.0083
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0041 0.4905
Giardia lamblia Protein tyrosine phosphatase 0.0037 0.0025 0.2776
Toxoplasma gondii hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0026 0.0029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0064
Onchocerca volvulus 0.0037 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Schistosoma mansoni acetylcholine receptor-related 0.0054 0.0044 0.0125
Echinococcus granulosus g protein coupled receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis insulin receptor 0.0152 0.015 0.0167
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0101
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0108 0.0101 0.0995
Onchocerca volvulus 0.0083 0.0075 0.0138
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.8529
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0002 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0026 0.0245
Toxoplasma gondii hypothetical protein 0.0027 0.0014 0.0014
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0019 0.0021
Leishmania major GTP-binding protein, putative 0.0021 0.0008 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Echinococcus granulosus carbonic anhydrase 0.046 0.0482 0.0538
Plasmodium vivax unspecified product 0.0105 0.0099 0.8785
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0022 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Schistosoma mansoni acetylcholine receptor subunit beta 0.0054 0.0044 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0108 0.0101 0.0326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0117
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0108 0.0101 0.0326
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0046 0.0077
Brugia malayi Steroid receptor seven-up type 2 0.0179 0.0179 0.03
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0087 0.008 0.0777
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0013 0.116
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0006 0.0017
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0037 0.0025 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0041 0.5125
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0014 0.0016
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0025 0.0028
Schistosoma mansoni polycystin 1-related 0.0535 0.0564 0.1618
Echinococcus granulosus expressed conserved protein 0.0185 0.0185 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Loa Loa (eye worm) fibroinase 0.0028 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0005
Echinococcus multilocularis geminin 0.0499 0.0525 0.0586
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0006
Schistosoma mansoni tyrosine kinase 0.0253 0.0259 0.0742
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0007 0.0008
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0015
Echinococcus granulosus tyrosine protein kinase Src64B 0.0014 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0095 0.0087 0.025
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Schistosoma mansoni ran 0.0021 0.0008 0.0023
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0152 0.015 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0026 0.3267
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Onchocerca volvulus 0.0034 0.0022 0.0041
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0037 0.0025 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) ACC-1 protein 0.0117 0.0112 0.0188
Onchocerca volvulus 0.0048 0.0037 0.0068
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.83 0.8964 1
Echinococcus granulosus neuropeptide receptor 0.0034 0.0022 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0014
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0108 0.0101 0.0995
Schistosoma mansoni amine GPCR 0.0034 0.0022 0.0064
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0061 0.0192
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0108 0.0101 0.0326
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0081 0.0073 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0037 0.0025 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0087 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0053 0.0153
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0116 0.0111 0.0357
Entamoeba histolytica cysteine protease, putative 0.0028 0.0015 0.0693
Brugia malayi amine oxidase, flavin-containing family protein 0.0083 0.0074 0.0125
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0026 0.0063
Brugia malayi RNA binding protein 0.0063 0.0053 0.0089
Brugia malayi G-protein coupled receptor 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0027
Brugia malayi CHE-14 protein 0.0085 0.0077 0.0128
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0004 0.0364
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0012 0.0026
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0117 0.0112 0.0188
Echinococcus granulosus cathepsin l1 0.0028 0.0015 0.0016
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0053 0.0089
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0006
Brugia malayi sulfakinin receptor protein 0.0034 0.0022 0.0037
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0019 0.0032
Loa Loa (eye worm) matrix metalloproteinase 0.2283 0.2455 0.4121
Chlamydia trachomatis protoporphyrinogen oxidase 0.0083 0.0074 1
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Schistosoma mansoni pcd6 interacting protein-related 0.0037 0.0025 0.0071
Echinococcus granulosus jumonji domain containing protein 0.008 0.0072 0.008
Toxoplasma gondii histone lysine methyltransferase SET1 0.0223 0.0227 0.0227
Mycobacterium ulcerans hypothetical protein 0.0038 0.0026 0.0075
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.01 0.0093 0.0103
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0005 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Brugia malayi orphan nuclear receptor NR2E1 0.0084 0.0076 0.0128
Onchocerca volvulus 0.0028 0.0015 0.0027
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0122 0.0396
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0022 0.0025
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0005 0.0006
Loa Loa (eye worm) steroid hormone receptor 0.0179 0.0179 0.03
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0095 0.0087 0.0097
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0037 0.0025 0.0028
Plasmodium vivax vivapain-2 0.0028 0.0015 0.1307
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1173 0.1254 0.4183
Schistosoma mansoni importin beta-1 0.0029 0.0016 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0037 0.0025 0.0042
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.046 0.0482 0.081
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0007 0.0012
Echinococcus multilocularis FTZ F1 alpha 0.0179 0.0179 0.0199
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0053 0.0153
Plasmodium falciparum cysteine proteinase falcipain 1 0.0118 0.0113 0.2314
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0053 0.0089
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0012
Brugia malayi Furin-like cysteine rich region family protein 0.0468 0.0491 0.0825
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0122 0.0385
Onchocerca volvulus 0.0054 0.0044 0.008
Loa Loa (eye worm) oxidoreductase 0.0021 0.0007 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0116 0.0111 0.0185
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.004 0.0044
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0039 0.0044
Onchocerca volvulus 0.0034 0.0022 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0253 0.0259 0.0289
Echinococcus granulosus bloom syndrome protein 0.0021 0.0007 0.0008
Echinococcus granulosus neuropeptide receptor 0.0034 0.0022 0.0025
Mycobacterium ulcerans beta-lactamase 0.0038 0.0026 0.0075
Trypanosoma brucei trans-sialidase, putative 0.0092 0.0085 0.0828
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0179 0.0179 0.0199
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.0179 0.0179 0.0327
Echinococcus multilocularis dnaJ subfamily B 0.124 0.1327 0.148
Schistosoma mansoni tyrosine kinase 0.0014 0.0001 0.0002
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0022 0.0008 0.0014
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0202 0.0578
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0006 0.0018
Brugia malayi hypothetical protein 0.0019 0.0005 0.0008
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0117 0.0112 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0026 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.001 0.0088
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.007
Schistosoma mansoni microtubule-associated protein tau 0.2718 0.2925 0.8389
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0026 0.0075
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0075 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0026 0.0013 0.0015
Schistosoma mansoni carbonic anhydrase-related 0.046 0.0482 0.1383
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0179 0.0179 0.0512
Echinococcus granulosus serotonin receptor 0.0034 0.0022 0.0025
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.001 0.0088
Brugia malayi beta-lactamase 0.0038 0.0026 0.0044
Schistosoma mansoni histamine h1 receptor 0.0034 0.0022 0.0064
Brugia malayi Bromodomain containing protein 0.0038 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0108 0.0101 0.0326
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0034 0.0022 0.0025
Brugia malayi TAR-binding protein 0.0063 0.0053 0.0089
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0026 0.0075
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.001
Brugia malayi Protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0152 0.015 0.0167
Mycobacterium leprae PROBABLE HYDROLASE 0.2781 0.2993 1
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0022 0.0008 0.0024
Loa Loa (eye worm) serotonin transporter b 0.0088 0.008 0.0134
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0039 0.0374
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0005 0.0006
Mycobacterium ulcerans hypothetical protein 0.0025 0.0012 0.0026
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0015 0.0016
Echinococcus granulosus lamin 0.0026 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.001 0.0022
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0117 0.0112 0.0188
Brugia malayi hypothetical protein 0.0015 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.83 0.8964 1
Brugia malayi Melatonin receptor type 1A 0.0034 0.0022 0.0037
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0083 0.0074 0.0236
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0015 0.0042
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0087 0.0146
Echinococcus granulosus tachykinin peptides receptor 99D 0.0034 0.0022 0.0025
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0083 0.0074 0.0224
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0027 0.0045
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0063
Schistosoma mansoni nAChR subunit 0.0054 0.0044 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0022 0.0025
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Echinococcus multilocularis cysteine protease 0.0028 0.0015 0.0016
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0041 0.5125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0247 0.0253 0.0724
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0015 0.0693
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0026 0.0245
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0061 0.0192
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Plasmodium falciparum protoporphyrinogen oxidase 0.0083 0.0074 0.1523
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Brugia malayi nuclear receptor RXR 0.0095 0.0087 0.0146
Schistosoma mansoni survival motor neuron protein 0.0048 0.0037 0.0106
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.005 0.0485
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0013 0.0022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0001 0.0097
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0061 0.0192
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.01 0.0093 0.0103
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Echinococcus granulosus cathepsin L 0.002 0.0006 0.0007
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0108 0.0101 0.0326
Onchocerca volvulus 0.0034 0.0022 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0006 0.001
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0008 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0108 0.0101 0.0326
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0 0.00000000097182
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0081 0.0073 0.0122
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0054 0.0522
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0014
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0077 0.0085
Loa Loa (eye worm) glutathione reductase 0.005 0.0039 0.0066
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0002
Echinococcus multilocularis serotonin transporter 0.0088 0.008 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus granulosus neuropeptide receptor A26 0.0034 0.0022 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Brugia malayi nuclear receptor NHR-88 0.0084 0.0076 0.0128
Brugia malayi AMP-binding enzyme family protein 0.007 0.0061 0.0103
Brugia malayi AMP-binding enzyme family protein 0.007 0.0061 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0026 0.3267
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0117 0.0112 0.0321
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0054 0.0044 0.0073
Schistosoma mansoni biogenic amine receptor 0.0034 0.0022 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0006 0.0017
Onchocerca volvulus 0.0088 0.008 0.0146
Echinococcus granulosus serotonin transporter 0.0088 0.008 0.0089
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0024 0.0027
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0005 0.0008
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0034 0.0022 0.0025
Brugia malayi PHD-finger family protein 0.0032 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Schistosoma mansoni amine oxidase 0.0083 0.0074 0.0213
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0041 0.0392
Onchocerca volvulus 0.0037 0.0025 0.0045
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0013
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0108 0.0101 0.0995
Echinococcus granulosus histone lysine methyltransferase setb 0.002 0.0006 0.0007
Schistosoma mansoni tyrosine kinase 0.0468 0.0491 0.1409
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0084 0.0076 0.0128
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0041 0.0046
Onchocerca volvulus 0.0028 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0006 0.001
Loa Loa (eye worm) integrin beta-2 0.045 0.0472 0.0792
Echinococcus multilocularis carbonic anhydrase 0.046 0.0482 0.0538
Brugia malayi nuclear receptor RXR 0.0084 0.0076 0.0128
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.004 0.0044
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0108 0.0101 0.0326
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.001 0.0874
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0006 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0021
Entamoeba histolytica hypothetical protein 0.0016 0.0002 0.0043
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0083 0.0074 0.6612
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0027 0.003
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0005 0.0008
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0007 0.0012
Brugia malayi nuclear hormone receptor family member nhr-6 0.0084 0.0076 0.0128
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0029 0.0033
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0022 0.0025
Plasmodium vivax vivapain-2 0.0028 0.0015 0.1307
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0016 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Loa Loa (eye worm) RecQ helicase 0.0021 0.0007 0.0012
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0005 0.0009
Brugia malayi nuclear hormone receptor 0.0179 0.0179 0.03
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0022 0.0037
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0005 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0022 0.0025
Echinococcus granulosus neuropeptide FF receptor 2 0.0034 0.0022 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0054 0.0044 0.0048
Trichomonas vaginalis STE family protein kinase 0.0087 0.008 1
Onchocerca volvulus 0.0117 0.0112 0.0205
Schistosoma mansoni hypothetical protein 0.3237 0.3487 1
Loa Loa (eye worm) DR-78 0.0084 0.0076 0.0128
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0048 0.008
Brugia malayi putative neuropeptide receptor NPR1 0.0034 0.0022 0.0037
Brugia malayi Doublecortin family protein 0.0039 0.0027 0.0045
Mycobacterium ulcerans hypothetical protein 0.0025 0.0012 0.0026
Onchocerca volvulus 0.0117 0.0112 0.0205
Entamoeba histolytica hypothetical protein 0.0109 0.0103 0.5159
Brugia malayi Protein kinase domain containing protein 0.0152 0.015 0.0251
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0005 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0076 0.0085
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.0034 0.0022 0.0041
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0179 0.0179 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0179 0.0179 0.03
Loa Loa (eye worm) hypothetical protein 0.007 0.0061 0.0103
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0108 0.0101 0.0326
Brugia malayi G protein-coupled receptor F59B2.13 0.0034 0.0022 0.0037
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0016 0.0018
Brugia malayi Importin beta-1 subunit 0.0029 0.0016 0.0027
Onchocerca volvulus 0.0034 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0022 0.0025
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0012 0.0013
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0024 0.004
Brugia malayi regulator of G-protein signaling egl-10 0.0027 0.0014 0.0024
Onchocerca volvulus 0.0117 0.0112 0.0205
Onchocerca volvulus 0.0037 0.0025 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0081 0.0073 0.021
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0026 0.0245
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Schistosoma mansoni nuclear receptor 0.0084 0.0076 0.0219
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0088 0.008 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Schistosoma mansoni nAChR subunit 0.0054 0.0044 0.0125
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0198 0.0221
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.01 0.0093 0.0103
Leishmania major hypothetical protein, conserved 0.0019 0.0005 0.0035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0044 0.0073
Schistosoma mansoni cpg binding protein 0.0125 0.0121 0.0345
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0022 0.0008 0.0009
Brugia malayi Dopamine receptor protein 1 0.0034 0.0022 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0054 0.0522
Loa Loa (eye worm) hypothetical protein 0.2283 0.2455 0.4121
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0041 0.5125
Loa Loa (eye worm) TK/EGFR protein kinase 0.0468 0.0491 0.0825
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.01 0.0093 0.0266
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi tailless protein 0.0084 0.0076 0.0128
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0008 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Brugia malayi fructose-bisphosphate aldolase 2 0.01 0.0093 0.0156
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0197 0.0198 0.0333
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0015 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Brugia malayi hypothetical protein 0.0039 0.0027 0.0045
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0028 0.0015 0.0284
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0001 0.0001
Brugia malayi Uncoordinated protein 44 0.0014 0 0.0000000014626
Brugia malayi hypothetical protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0008
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0015 0.0027
Plasmodium vivax JmjC domain containing protein 0.0019 0.0005 0.0453
Plasmodium vivax unspecified product 0.0118 0.0113 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Trypanosoma brucei trans-sialidase, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0054 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0179 0.0179 0.03
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0736
Plasmodium falciparum glutathione reductase 0.005 0.0039 0.0791
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0074 0.6612
Brugia malayi glutathione reductase 0.005 0.0039 0.0066
Schistosoma mansoni neuropeptide receptor 0.0034 0.0022 0.0064
Echinococcus granulosus peptide allatostatin:somatostatin 0.0034 0.0022 0.0025
Plasmodium falciparum carbonic anhydrase 0.046 0.0482 1
Loa Loa (eye worm) CYP4Cod1 0.0116 0.0111 0.0185
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0026 0.0075
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0028 0.0015 0.0027
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0023 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Brugia malayi ecdysteroid receptor 0.0179 0.0179 0.03
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.01 0.0093 0.0909
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0054 0.0044 0.0073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0117
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0189 0.019 0.0212
Schistosoma mansoni lamin 0.0026 0.0013 0.0038
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0087 0.008 0.0777
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Echinococcus multilocularis carbonic anhydrase II 0.0942 0.1004 0.112
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0117 0.0112 0.0188
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0053 0.0153
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0045
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0022 0.0064
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0108 0.0101 0.0995
Onchocerca volvulus 0.0034 0.0022 0.0041
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0081 0.0073 0.1483
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.01 0.0093 0.0093
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0007 0.0007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0006 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0108 0.0101 0.0326
Echinococcus granulosus nAChR subunit 0.0117 0.0112 0.0125
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0027 0.003
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.046 0.0482 0.081
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0024 0.0027
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0007 0.0131
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0014 0.0016
Echinococcus multilocularis cpg binding protein 0.0125 0.0121 0.0134
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.01 0.0093 0.0103
Brugia malayi ORL1-like opioid receptor 0.0034 0.0022 0.0037
Schistosoma mansoni carbonic anhydrase-related 0.046 0.0482 0.1383
Mycobacterium leprae conserved hypothetical protein 0.0023 0.001 0.001
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0037 0.0025 0.0042
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.024 0.0268
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1451 0.1555 0.1734
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0093 0.0103
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0026 0.2326
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0054 0.0522
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0037 0.0025 0.0042
Schistosoma mansoni tyrosine kinase 0.0152 0.015 0.0429
Brugia malayi Raf kinase 0.025 0.0255 0.0429
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0026 0.0075
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.029 0.0323
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0076 0.0219
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Schistosoma mansoni zinc finger protein 0.0015 0.0002 0.0005
Brugia malayi neuropeptide F receptor 0.0034 0.0022 0.0037
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0117 0.0112 0.0188
Plasmodium vivax amine transporter, putative 0.0015 0.0001 0.009
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0007 0.0007
Brugia malayi RE15519p 0.0034 0.0022 0.0037
Plasmodium falciparum zinc finger protein, putative 0.0016 0.0002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0068 0.0059 0.0098
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0122 0.0396
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0108 0.0101 0.0326
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0034 0.0022 0.0025
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0093 0.0155
Leishmania major cathepsin L-like protease 0.0028 0.0015 0.0131
Echinococcus multilocularis 0.0108 0.0101 0.0113
Loa Loa (eye worm) nuclear hormone receptor 0.0084 0.0076 0.0128
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0008 0.0024
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0007 0.0058
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0014 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0034 0.0022 0.0064
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0022 0.0025
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0007 0.0012
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0054 0.0044 0.0073
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0054 0.0044 0.0048
Schistosoma mansoni rab6-interacting 0.0039 0.0027 0.0077
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.007 0.02
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0041 0.0029 0.0049
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0036 0.0103
Echinococcus multilocularis lamin 0.0026 0.0013 0.0015
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0006
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0109 0.0339
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0063
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0108 0.0101 0.0326
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0005 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0117 0.0112 0.0188
Loa Loa (eye worm) nuclear receptor NHR-67 0.0084 0.0076 0.0128
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0022 0.0064
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.002 0.0006 0.0046
Trichomonas vaginalis helicase, putative 0.0026 0.0014 0.1673
Trichomonas vaginalis pten, drome, putative 0.0037 0.0025 0.3087
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0012 0.0099
Echinococcus multilocularis neuropeptide FF receptor 2 0.0034 0.0022 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0022 0.0025
Mycobacterium ulcerans dehydrogenase 0.0083 0.0074 0.0236
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0108 0.0101 0.0326
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0069 0.0076
Echinococcus multilocularis G-protein coupled receptor, putative 0.0034 0.0022 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0006
Echinococcus granulosus fmrfamide receptor 0.0034 0.0022 0.0025
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0084 0.0076 0.0128
Echinococcus multilocularis glycine receptor subunit beta 0.0117 0.0112 0.0125
Echinococcus granulosus zinc finger protein 0.0026 0.0014 0.0015
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0179 0.0179 0.0512
Brugia malayi Cation transporter family protein 0.0117 0.0112 0.0188
Onchocerca volvulus 0.0038 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0179 0.0179 0.03
Schistosoma mansoni hypothetical protein 0.0307 0.0317 0.0909
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0108 0.0101 0.0326
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0108 0.0101 0.0326
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0026 0.0029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0022 0.0025
Plasmodium falciparum phd finger protein, putative 0.0058 0.0048 0.0964
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0081 0.0073 0.0707
Brugia malayi hypothetical protein 0.0019 0.0005 0.0008
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0069 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0179 0.0179 0.0512
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Echinococcus granulosus glycine receptor subunit beta 0.0117 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0085 0.0077 0.0128
Brugia malayi AKH receptor 0.0034 0.0022 0.0037
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0026 0.0075
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.2283 0.2455 0.4121
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0048 0.0048
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0005 0.0015
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0037 0.0025 0.0028
Loa Loa (eye worm) protein tyrosine phosphatase 0.0037 0.0025 0.0042
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0048 0.0053
Schistosoma mansoni neurotransmitter gated ion channel 0.0063 0.0053 0.0153
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0081 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Echinococcus multilocularis neuropeptide s receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0061 0.018
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0083 0.0074 0.0213
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0108 0.0101 0.0326
Onchocerca volvulus 0.0037 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0015 0.1821
Onchocerca volvulus 0.0028 0.0015 0.0027
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0014 0.0016
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0007 0.0012
Schistosoma mansoni hypothetical protein 0.0068 0.0059 0.0168
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0262
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0005 0.0006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0006 0.001
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0117 0.0112 0.0188
Leishmania major hypothetical protein, conserved 0.0213 0.0216 0.2135
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0001 0.0003
Leishmania major cathepsin L-like protease 0.0028 0.0015 0.0131
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Brugia malayi Cation transporter family protein 0.0117 0.0112 0.0188
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0198 0.0221
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0146
Echinococcus multilocularis 0.0144 0.0141 0.0157
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0008 0.0009
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Loa Loa (eye worm) hypothetical protein 0.0175 0.0175 0.0293
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0179 0.0179 0.03
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0014
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0942 0.1004 0.1686
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi hypothetical protein 0.0236 0.024 0.0403
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0041 0.0392
Echinococcus granulosus single minded 2 0.0035 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Mycobacterium leprae Conserved hypothetical protein 0.0108 0.0101 0.0315
Schistosoma mansoni bromodomain containing protein 0.007 0.0061 0.0175
Onchocerca volvulus 0.0035 0.0023 0.0041
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Echinococcus multilocularis carbonic anhydrase 0.046 0.0482 0.0538
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0117 0.0112 0.0125
Brugia malayi Kelch motif family protein 0.007 0.006 0.0101
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1173 0.1254 0.4183
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Schistosoma mansoni neurotransmitter gated ion channel 0.0054 0.0044 0.0125
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0081 0.0073 0.0208
Trypanosoma cruzi cysteine proteinase, putative 0.002 0.0006 0.0046
Brugia malayi fructose-bisphosphate aldolase 1 0.01 0.0093 0.0156
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.004 0.0121
Echinococcus multilocularis musashi 0.0026 0.0013 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0022 0.0037
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0026 0.3267
Brugia malayi Tachykinin-like peptides receptor 99D 0.0034 0.0022 0.0037
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0198 0.0333
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0262
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0015 0.0027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0095 0.0087 0.025
Onchocerca volvulus 0.0037 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0265 0.076
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0189 0.019 0.0212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0093 0.0103
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.046 0.0482 0.081
Echinococcus granulosus cathepsin l cysteine peptidase 0.0028 0.0015 0.0016
Loa Loa (eye worm) kelch domain-containing protein family protein 0.007 0.006 0.0101
Echinococcus multilocularis expressed protein 0.0361 0.0375 0.0418
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0179 0.0179 0.0199
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0117 0.0112 0.0125
Loa Loa (eye worm) hypoxia-induced factor 1 0.0145 0.0142 0.0239
Echinococcus granulosus cpg binding protein 0.0125 0.0121 0.0134
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0034 0.0022 0.0064
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0109 0.035
Loa Loa (eye worm) hypothetical protein 0.0099 0.0092 0.0155
Schistosoma mansoni RAR-like nuclear receptor 0.0179 0.0179 0.0512
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0048 0.0053
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0008 0.0024
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0014 0.1221
Echinococcus granulosus 7TM GPCR rhodopsin 0.0034 0.0022 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.0088 0.008 0.0229
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0179 0.0179 0.0512
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0015 0.0131
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0041 0.0392
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0037 0.0025 0.0071
Brugia malayi MAP kinase sur-1 0.0052 0.0041 0.0069
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0093 0.0265
Brugia malayi Cytochrome P450 family protein 0.0147 0.0144 0.0242
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Mycobacterium ulcerans hypothetical protein 0.007 0.0061 0.0192
Toxoplasma gondii hypothetical protein 0.0015 0.0001 0.0001
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0081 0.0073 0.6442
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0007 0.0012
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0007 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0024 0.0027
Onchocerca volvulus 0.0039 0.0027 0.0049
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Entamoeba histolytica hypothetical protein 0.0109 0.0103 0.5159
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.01 0.0093 0.0156
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0014 0.0001 0.0001
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0054 0.0044 0.0073
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Schistosoma mansoni zinc finger protein 0.0026 0.0014 0.0039
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0028 0.0015 0.0027
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0087 0.008 0.0134
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0005 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0179 0.0179 0.0512
Echinococcus granulosus snurportin 1 0.0307 0.0317 0.0354
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.01 0.0093 0.0909
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus granulosus tar DNA binding protein 0.0063 0.0053 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0027 0.003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0034 0.0022 0.0025
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0194
Brugia malayi jmjC domain containing protein 0.0019 0.0005 0.0009
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0012 0.0026
Schistosoma mansoni amine GPCR 0.0034 0.0022 0.0064
Brugia malayi hypothetical protein 0.0037 0.0025 0.0042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0034 0.0022 0.0025
Leishmania major cytochrome p450-like protein 0.0108 0.0101 0.0995
Echinococcus multilocularis sex peptide receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0012 0.1417
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0006 0.001
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0054 0.006
Loa Loa (eye worm) TK/INSR protein kinase 0.0152 0.015 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0077 0.961
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trichomonas vaginalis STE family protein kinase 0.0087 0.008 1
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0117 0.0112 0.0188
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0077 0.0085
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis zinc finger protein 0.0026 0.0014 0.0015
Onchocerca volvulus Matrilysin homolog 0.5063 0.5463 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0026 0.0044
Trypanosoma cruzi UDP-galactopyranose mutase 0.0083 0.0074 0.0726
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0012 0.0099
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.0217
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium tuberculosis Conserved protein 0.0038 0.0026 0.0075
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0007 0.065
Entamoeba histolytica cysteine proteinase 1, putative 0.002 0.0006 0.0262
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0005 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Echinococcus granulosus glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Schistosoma mansoni hypothetical protein 0.0058 0.0048 0.0136
Onchocerca volvulus 0.0037 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0045
Brugia malayi jmjC domain containing protein 0.0019 0.0005 0.0009
Leishmania major hypothetical protein, conserved 0.0038 0.0026 0.0245
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.1673
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0084 0.0076 0.0219
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0007 0.0889
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0146
Echinococcus granulosus geminin 0.0499 0.0525 0.0586
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0044 0.0073
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0179 0.0179 0.03
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0942 0.1004 0.1686
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Onchocerca volvulus 0.0026 0.0013 0.0024
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0109 0.035
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0054 0.0155
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0037 0.0025 0.1202
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0262
Echinococcus multilocularis serotonin receptor 0.0034 0.0022 0.0025
Leishmania major UDP-galactopyranose mutase 0.0083 0.0074 0.0726
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0039 0.0118
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.029 0.0323
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.002 0.0006 0.0007
Onchocerca volvulus 0.0063 0.0053 0.0098
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0117 0.0112 0.0188
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0146
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0028 0.0015 0.0284
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) ACC-1 protein 0.0117 0.0112 0.0188
Echinococcus granulosus tyrosine protein kinase Lyn 0.0015 0.0002 0.0002
Echinococcus granulosus insulin receptor 0.0152 0.015 0.0167
Onchocerca volvulus 0.0034 0.0022 0.0041
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0942 0.1004 0.1686
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0044 0.0073
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0007 0.0012
Schistosoma mansoni tyrosine kinase 0.0014 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0499 0.0525 0.1506
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Plasmodium vivax vivapain-3 0.002 0.0006 0.0551
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.5651 0.6098 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0179 0.0179 0.0199
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1451 0.1555 0.261
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0037 0.0025 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0093 0.0265
Brugia malayi Bromodomain containing protein 0.006 0.005 0.0084
Brugia malayi Serotonin receptor 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0087 0.008 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Schistosoma mansoni loxhd1 0.0039 0.0027 0.0077
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0108 0.0101 0.0326
Onchocerca volvulus 0.0084 0.0076 0.014
Echinococcus granulosus cytochrome P450 2K1 0.0108 0.0101 0.0113
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0053 0.0089
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Schistosoma mansoni amine GPCR 0.0169 0.0168 0.0482
Trypanosoma brucei cytochrome P450, putative 0.0116 0.0111 0.1086
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0014
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0007 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0108 0.0101 0.0326
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0093 0.0265
Loa Loa (eye worm) cytochrome P450 0.0108 0.0101 0.017
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0093 0.0155
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0093 0.0155
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0063 0.0053 0.0153
Onchocerca volvulus 0.0038 0.0026 0.0048
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0076 0.0085
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0061 0.3052
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0007 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0006 0.0018
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0108 0.0101 0.0326
Onchocerca volvulus 0.3237 0.3487 0.6383
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0012 0.0099
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0034 0.0022 0.0037
Echinococcus granulosus epidermal growth factor receptor 0.0468 0.0491 0.0548
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0014 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0108 0.0101 0.0326
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0081 0.0073 0.0707
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0001 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.0034 0.0022 0.0025
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0005 0.0085
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0014
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0108 0.0101 0.0326
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0076 0.0085
Onchocerca volvulus 0.0037 0.0025 0.0045
Onchocerca volvulus 0.0037 0.0025 0.0045
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0026 0.3267
Onchocerca volvulus 0.0037 0.0025 0.0045
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0232 0.0236 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Toxoplasma gondii ABC1 family protein 0.0038 0.0026 0.0026
Brugia malayi hypothetical protein 0.0095 0.0087 0.0146
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0026 0.0075
Loa Loa (eye worm) hypothetical protein 0.0158 0.0156 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0016 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Onchocerca volvulus 0.0084 0.0076 0.014
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Toxoplasma gondii thioredoxin reductase 0.005 0.0039 0.0039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Echinococcus granulosus hypothetical protein 0.0034 0.0022 0.0025
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0117 0.0112 0.0188
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0022 0.0008 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0006 0.0018
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0037 0.0025 0.0071
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0008 0.0024
Echinococcus multilocularis tyrosine protein kinase Abl 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.0037 0.0025 0.0045
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0023 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0053 0.0153
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0084 0.0076 0.0085
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.0054 0.0044 0.008
Onchocerca volvulus 0.0021 0.0007 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Brugia malayi Cytochrome P450 family protein 0.0116 0.0111 0.0185
Trypanosoma brucei trans-sialidase, putative 0.0092 0.0085 0.0828
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0108 0.0101 0.0326
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0037 0.0025 0.0071
Echinococcus granulosus glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.0263 0.0441
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.01 0.0093 0.8248
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.2283 0.2455 0.704
Schistosoma mansoni thyroid hormone receptor 0.0179 0.0179 0.0512
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0007 0.0058
Leishmania major trypanothione reductase 0.005 0.0039 0.0374
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0008 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0117 0.0112 0.0321
Brugia malayi Serotonin receptor 0.0034 0.0022 0.0037
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Schistosoma mansoni amine oxidase 0.0083 0.0074 0.0213
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0022 0.0037
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0199
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0006
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) solute carrier family 6 member 4 0.0088 0.008 0.0134
Echinococcus granulosus lysine specific histone demethylase 1A 0.0083 0.0074 0.0083
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0179 0.0179 0.03
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0075 0.0126
Brugia malayi Cathepsin L-like cysteine proteinase 0.0015 0.0001 0.0002
Onchocerca volvulus 0.0037 0.0025 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0015 0.1821
Entamoeba histolytica hypothetical protein 0.0063 0.0053 0.2649
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0061 0.0192
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0019 0.0032
Echinococcus granulosus dual specificity mitogen activated protein 0.0087 0.008 0.0089
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0006 0.0318
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0045
Trypanosoma brucei trans-sialidase, putative 0.0092 0.0085 0.0828
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0069 0.0069
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0462
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0023 0.0025
Onchocerca volvulus 0.0063 0.0053 0.0098
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0019 0.0021
Schistosoma mansoni opsin-like receptor 0.0034 0.0022 0.0064
Brugia malayi hypothetical protein 0.0054 0.0044 0.0073
Schistosoma mansoni tyrosine kinase 0.0152 0.015 0.0429
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0076 0.014
Onchocerca volvulus 0.0037 0.0025 0.0045
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0022 0.0008 0.1009
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.01 0.0093 0.0103
Onchocerca volvulus 0.0015 0.0001 0.0002
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus granulosus g protein coupled receptor 0.0034 0.0022 0.0025
Entamoeba histolytica hypothetical protein 0.0109 0.0103 0.5159
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0179 0.0179 0.03
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0179 0.0179 0.0199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.2283 0.2455 0.4494
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0034 0.0022 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Brugia malayi CXXC zinc finger family protein 0.0117 0.0111 0.0187
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0006 0.0318
Brugia malayi hypothetical protein 0.0109 0.0103 0.0172
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0054 0.006
Loa Loa (eye worm) hypothetical protein 0.007 0.0061 0.0103
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0007 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Schistosoma mansoni alpha-1 adrenergic receptor 0.0034 0.0022 0.0064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0009
Onchocerca volvulus 0.0028 0.0015 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0108 0.0101 0.0326
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0037 0.0025 0.0028
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0014
Echinococcus multilocularis GPCR, family 2 0.0031 0.0019 0.0021
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.0217
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0749
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0109 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0179 0.0179 0.03
Onchocerca volvulus 0.0034 0.0022 0.0041
Echinococcus granulosus tyrosine protein kinase Src42A 0.0014 0.0001 0.0001
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0014 0.0021
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.007 0.0061 0.0103
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0007 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0108 0.0101 0.0326
Brugia malayi larval opioid receptor 0.0034 0.0022 0.0037
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0081 0.0073 0.0122
Loa Loa (eye worm) LGC-31 protein 0.0117 0.0112 0.0188
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Plasmodium vivax glutathione reductase, putative 0.005 0.0039 0.3475
Schistosoma mansoni tyrosine kinase 0.0247 0.0252 0.0723
Loa Loa (eye worm) cysteine protease 0.0028 0.0015 0.0025
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.046 0.0482 0.1383
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0063 0.0053 0.0089
Onchocerca volvulus 0.0117 0.0111 0.0203
Plasmodium vivax importin-beta 2, putative 0.0029 0.0016 0.1426
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0004 0.0056
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0117 0.0112 0.0188
Echinococcus multilocularis glycine receptor subunit beta 0.0117 0.0112 0.0125
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0007 0.0012
Brugia malayi SRC-1 0.0014 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0262
Brugia malayi Matrixin family protein 0.2283 0.2455 0.4121
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0013 0.0022
Brugia malayi hypothetical protein 0.0054 0.0044 0.0073
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0007 0.0889
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0042 0.0401
Toxoplasma gondii hypothetical protein 0.046 0.0482 0.0482
Brugia malayi GnHR receptor homolog 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Toxoplasma gondii histone lysine-specific demethylase 0.0083 0.0074 0.0074
Brugia malayi beta-lactamase family protein 0.0038 0.0026 0.0044
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0232 0.0236 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0069 0.0197
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0007 0.0058
Schistosoma mansoni protein kinase 0.0087 0.008 0.0228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0004 0.0432
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0004 0.0327
Brugia malayi Cation transporter family protein 0.0117 0.0112 0.0188
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0074 0.6612
Schistosoma mansoni integrin beta subunit 0.0262 0.0268 0.0769
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0001 0.0003
Brugia malayi Protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0071 0.0062 0.0104
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0179 0.0179 0.0512
Echinococcus granulosus carbonic anhydrase 0.046 0.0482 0.0538
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0034 0.0022 0.0037
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Echinococcus granulosus ecdysone induced protein 78C 0.0179 0.0179 0.0199
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0001 0.0003
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0061 0.018
Echinococcus granulosus allatostatin A receptor 0.0034 0.0022 0.0025
Schistosoma mansoni jumonji domain containing protein 0.015 0.0148 0.0423
Trypanosoma brucei protein tyrosine phosphatase 1 0.0037 0.0025 0.0231
Mycobacterium ulcerans lipase LipD 0.0038 0.0026 0.0075
Plasmodium falciparum glutathione reductase 0.0017 0.0004 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0022 0.0025
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.004 0.0109
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0061 0.0595
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0022 0.0025
Onchocerca volvulus 0.0034 0.0022 0.0041
Treponema pallidum sodium- and chloride- dependent transporter 0.0088 0.008 1
Echinococcus granulosus peregrin 0.006 0.005 0.0056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.1403
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.0061 0.0068
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Trypanosoma cruzi cysteine protease, putative 0.002 0.0006 0.0046
Brugia malayi jmjC domain containing protein 0.0189 0.019 0.0318
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Leishmania major fructose-1,6-bisphosphate aldolase 0.01 0.0093 0.0909
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0005 0.0008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0103 0.0115
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.009 0.0082 0.0082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0093 0.0103
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0042 0.0128
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0117 0.0112 0.0188
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0007 0.0012
Loa Loa (eye worm) matrixin family protein 0.552 0.5956 1
Echinococcus multilocularis hypothetical protein 0.0037 0.0025 0.0028
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0008 0.0695
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0179 0.0179 0.03
Brugia malayi beta-lactamase family protein 0.0038 0.0026 0.0044
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0015 0.0001 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0179 0.0179 0.0512
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0088 0.008 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Schistosoma mansoni hypothetical protein 0.0081 0.0073 0.021
Brugia malayi Cathepsin L-like precursor 0.0015 0.0001 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0109 0.035
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0007 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0076 0.0219
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0045
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0022 0.0025
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.01 0.0093 0.0093
Onchocerca volvulus Neuropeptide F receptor homolog 0.0034 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Onchocerca volvulus 0.0015 0.0001 0.0002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Toxoplasma gondii exonuclease III APE 0.002 0.0006 0.0006
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0545
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Brugia malayi excitatory GABA receptor EXP-1A 0.0117 0.0112 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Schistosoma mansoni cpg binding protein 0.0117 0.0111 0.0319
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0041 0.0392
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0026 0.0075
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0037 0.0025 0.0028
Brugia malayi Matrixin family protein 0.2283 0.2455 0.4121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0025
Brugia malayi AMP-binding enzyme family protein 0.007 0.0061 0.0103
Echinococcus granulosus orexin receptor type 2 0.0034 0.0022 0.0025
Entamoeba histolytica hypothetical protein 0.0109 0.0103 0.5159
Brugia malayi jmjC domain containing protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0026 0.0044
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.018 0.0179 0.02
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0009
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0108 0.0101 0.0326
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Brugia malayi nuclear hormone receptor 0.0084 0.0076 0.0128
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0006 0.0045
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0005 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0026 0.3267
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0 0.00000000097182
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0008 0.1009
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0006 0.0046
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0179 0.0179 0.0199
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Schistosoma mansoni neuropeptide f receptor 76f 0.0034 0.0022 0.0064
Schistosoma mansoni carbonic anhydrase-related 0.046 0.0482 0.1383
Echinococcus multilocularis G protein coupled receptor 139 0.0034 0.0022 0.0025
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0005 0.0593
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trypanosoma brucei trypanothione reductase 0.005 0.0039 0.0374
Mycobacterium tuberculosis Conserved protein 0.0025 0.0012 0.0026
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0942 0.1004 1
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0076 0.0128
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0034 0.0022 0.0064
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0026 0.0075
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0053 0.0059
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.0175 0.032
Onchocerca volvulus Matrix metalloproteinase homolog 0.5063 0.5463 1
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0064 0.0622
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0012 0.0026
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.001 0.0022
Onchocerca volvulus 0.0028 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Loa Loa (eye worm) hypothetical protein 0.0083 0.0075 0.0126
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0007 0.0012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0006 0.0106
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0022 0.0064
Onchocerca volvulus Alhambra homolog 0.0058 0.0048 0.0087
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0042 0.3727
Schistosoma mansoni biogenic amine receptor 0.0034 0.0022 0.0064
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0006 0.0038
Schistosoma mansoni hypothetical protein 0.0021 0.0008 0.0021
Onchocerca volvulus Bile acid receptor homolog 0.0179 0.0179 0.0327
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0049
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0061 0.0595
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Schistosoma mansoni hypothetical protein 0.0048 0.0037 0.0106
Brugia malayi G protein-coupled receptor 0.0034 0.0022 0.0037
Echinococcus multilocularis 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Brugia malayi photoreceptor-specific nuclear receptor 0.0179 0.0179 0.03
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0069 0.0205
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0015 0.0016
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0022 0.0008 0.0014
Mycobacterium leprae Probable lipase LipE 0.0038 0.0026 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0179 0.0179 0.03
Schistosoma mansoni intermediate filament proteins 0.0026 0.0013 0.0038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0093 0.0155
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) norepinephrine transporter 0.0088 0.008 0.0134
Schistosoma mansoni coup transcription factor 0.0179 0.0179 0.0512
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0034 0.0022 0.0037
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis neuropeptide receptor A26 0.0034 0.0022 0.0025
Brugia malayi cathepsin L-like precursor 0.0015 0.0001 0.0002
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0007 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0022 0.0064
Echinococcus granulosus phd:f box containing protein 0.0019 0.0005 0.0006
Brugia malayi hypothetical protein 0.0084 0.0076 0.0128
Echinococcus granulosus lysine specific demethylase 5A 0.0078 0.007 0.0078
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0248 0.0818
Schistosoma mansoni protein tyrosine phosphatase 0.0037 0.0025 0.0071
Echinococcus granulosus nAChR subunit 0.0063 0.0053 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0117 0.0112 0.0125
Brugia malayi hypoxia-induced factor 1 0.0145 0.0142 0.0239
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0117 0.0112 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0108 0.0101 0.0326
Schistosoma mansoni ran 0.0021 0.0008 0.0023
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0034 0.0022 0.0037
Schistosoma mansoni hypothetical protein 0.124 0.1327 0.3804
Onchocerca volvulus 0.0021 0.0007 0.0013
Echinococcus granulosus raf serine:threonine protein kinase 0.0259 0.0265 0.0296
Leishmania major cathepsin L-like protease 0.0028 0.0015 0.0131
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Echinococcus granulosus fructose bisphosphate aldolase class I 0.01 0.0093 0.0103
Loa Loa (eye worm) hypothetical protein 0.046 0.0482 0.081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0006 0.0045
Brugia malayi Hemopexin family protein 0.3237 0.3487 0.5854
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Schistosoma mansoni protein tyrosine phosphatase 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0008
Echinococcus granulosus expressed protein 0.0361 0.0375 0.0418
Echinococcus granulosus thyroid hormone receptor alpha 0.0084 0.0076 0.0085
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0015 0.0016
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0054 0.0044 0.0048
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0005 0.0009
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0081 0.0073 0.0122
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0081 0.0073 0.0707
Onchocerca volvulus 0.0034 0.0022 0.0041
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0048 0.4218
Onchocerca volvulus 0.0034 0.0022 0.0041
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0179 0.0179 0.0199
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0014 0.0001 0.0001
Leishmania major cytochrome p450-like protein 0.0116 0.0111 0.1086
Schistosoma mansoni lipoxygenase 0.0162 0.016 0.0459
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0081 0.0073 0.9106
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0117 0.0112 0.0125
Trichomonas vaginalis ran, putative 0.0021 0.0008 0.0953
Leishmania major cathepsin L-like protease 0.0028 0.0015 0.0131
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0108 0.0101 0.0326
Onchocerca volvulus 0.0034 0.0022 0.0041
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0117 0.0112 0.0321
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0001 0.0001
Brugia malayi Dopamine receptor protein 2 0.0034 0.0022 0.0037
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0034 0.0022 0.0037
Mycobacterium tuberculosis Probable reductase 0.0114 0.0109 0.035
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0942 0.1004 0.2879
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0108 0.0101 0.0326
Brugia malayi Cathepsin L-like precursor 0.0015 0.0001 0.0002
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.046 0.0482 0.081
Schistosoma mansoni retinoic acid receptor RXR 0.0274 0.0282 0.0808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Onchocerca volvulus 0.0021 0.0007 0.0013
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Brugia malayi nuclear receptor NHR-67 0.0084 0.0076 0.0128
Echinococcus multilocularis cysteine protease 0.0028 0.0015 0.0016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0109 0.035
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0117 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Echinococcus granulosus glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Onchocerca volvulus 0.0021 0.0007 0.0013
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0117 0.0112 0.0188
Echinococcus granulosus microtubule associated protein 2 0.2718 0.2925 0.3263
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0007 0.0012
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Brugia malayi follicle stimulating hormone receptor 0.0257 0.0263 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0942 0.1004 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.002 0.0006 0.0018
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0062 0.0069
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.2781 0.2993 0.5025
Giardia lamblia PHD finger protein 15 0.0058 0.0048 0.5769
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Echinococcus granulosus nuclear receptor nhr 48 0.0084 0.0076 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0041 0.0117
Echinococcus granulosus GPCR family 2 0.0031 0.0019 0.0021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0103 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0041 0.5125
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0034 0.0022 0.0037
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Leishmania major cathepsin L-like protease 0.0073 0.0064 0.0622
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0117 0.0112 0.0321
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0006 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0004 0.0021
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0015 0.0025
Echinococcus multilocularis nAChR subunit 0.0117 0.0112 0.0125
Trypanosoma cruzi cytochrome P450, putative 0.0116 0.0111 0.1086
Trypanosoma brucei protein kinase, putative 0.0052 0.0041 0.0392
Echinococcus multilocularis protein patched 0.0085 0.0077 0.0085
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0014 0.0001 0.0001
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0081 0.0073 0.0073
Onchocerca volvulus Cathepsin F homolog 0.0028 0.0015 0.0027
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0007 0.0879
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0048 0.0136
Brugia malayi hypothetical protein 0.0158 0.0156 0.0261
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0041 0.0029 0.0033
Onchocerca volvulus 0.0037 0.0025 0.0045
Schistosoma mansoni hypothetical protein 0.0109 0.0103 0.0295
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0069 0.0076
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0006 0.0008
Echinococcus multilocularis RUN 0.0039 0.0027 0.003
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0108 0.0101 0.0326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0007 0.0012
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0199
Schistosoma mansoni myst-related protein 0.0016 0.0002 0.0006
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0014 0.0001 0.0002
Echinococcus multilocularis peregrin 0.006 0.005 0.0056
Brugia malayi Thioredoxin reductase 0.005 0.0039 0.0066
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0088 0.008 0.0229
Brugia malayi Dopamine receptor 0.0034 0.0022 0.0037
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0022 0.0008 0.0009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0032
Leishmania major cathepsin L-like protease 0.0028 0.0015 0.0131
Loa Loa (eye worm) hypothetical protein 0.0236 0.024 0.0403
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0004 0.0021
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0005 0.0008
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0006 0.0004
Schistosoma mansoni tyrosine kinase 0.0253 0.0259 0.0742
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0028 0.0015 0.0025
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0053 0.0153
Leishmania major importin beta-1 subunit, putative 0.0023 0.001 0.0086
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0005 0.0005
Brugia malayi AF-10 protein 0.0019 0.0006 0.0009
Trypanosoma brucei carbonic anhydrase-like protein 0.0942 0.1004 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Echinococcus multilocularis c src tyrosine kinase 0.0014 0.0001 0.0001
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.1868 0.2006 0.5752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0095 0.0087 0.0146
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0146
Brugia malayi N-terminal motif family protein 0.0175 0.0175 0.0293
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0004 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) ctsf protein 0.0028 0.0015 0.0025
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0037 0.0025 0.0045
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.007
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.01 0.0093 0.0266
Echinococcus granulosus c src tyrosine kinase 0.0014 0.0001 0.0001
Brugia malayi G-protein coupled receptor 0.0034 0.0022 0.0037
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0061 0.0595
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0065
Schistosoma mansoni tyrosine kinase 0.0014 0.0001 0.0002
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0013
Schistosoma mansoni cytochrome P450 0.0108 0.0101 0.0291
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0216 0.2135
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Leishmania major cathepsin L-like protease 0.0073 0.0064 0.0622
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.01 0.0093 0.0909
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0117 0.0112 0.0125
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.921
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0022 0.0025
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0001 0.0001
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0037 0.0025 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0053 0.0153
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0017 0.0019
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Onchocerca volvulus 0.0037 0.0025 0.0045
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0108 0.0101 0.0326
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0005 0.0073
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0117 0.0112 0.0125
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0117 0.0112 0.0188
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0001
Schistosoma mansoni protein tyrosine phosphatase 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0026 0.0044
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0008 0.0024
Echinococcus granulosus dnaJ subfamily B 0.124 0.1327 0.148
Loa Loa (eye worm) hypothetical protein 0.0063 0.0053 0.0089
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0077 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0076 0.014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Leishmania major tyrosine specific protein phosphatase, putative 0.0037 0.0025 0.0231
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0006 0.0542
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Plasmodium vivax vivapain-1 0.0118 0.0113 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0041 0.0046
Mycobacterium tuberculosis Conserved protein 0.0038 0.0026 0.0075
Brugia malayi intermediate filament protein 0.0026 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Echinococcus multilocularis microtubule associated protein 2 0.2718 0.2925 0.3263
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0083 0.0074 0.1523
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.0179 0.0199
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.0039 0.0027 0.0077
Echinococcus multilocularis raf serine:threonine protein kinase 0.0259 0.0265 0.0296
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0021
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0076 0.0085
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0027 0.0014 0.0024
Onchocerca volvulus 0.0037 0.0025 0.0045
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0179 0.0179 0.0199
Schistosoma mansoni neuropeptide receptor 0.0034 0.0022 0.0064
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0019 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0022 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0059 0.0098
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0027 0.003
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0054 0.0044 0.0073
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0007 0.0058
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Onchocerca volvulus 0.0038 0.0026 0.0048
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0001 0.0001
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0004 0.0004
Echinococcus granulosus cathepsin L cysteine protease 0.002 0.0006 0.0007
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Schistosoma mansoni carbonic anhydrase 0.046 0.0482 0.1383
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Brugia malayi Protein-tyrosine phosphatase 1 0.0037 0.0025 0.0042
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0117 0.0112 0.0188
Schistosoma mansoni lamin 0.0026 0.0013 0.0038
Onchocerca volvulus 0.0083 0.0074 0.0136
Onchocerca volvulus Protein ultraspiracle homolog 0.0179 0.0179 0.0327
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0 0.00000000047923
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0027 0.0536
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0006 0.0007
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0003 0.0007
Entamoeba histolytica cysteine proteinase 2 0.002 0.0006 0.0262
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0022 0.0025
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.01 0.0093 0.0103
Leishmania major carbonic anhydrase-like protein 0.0942 0.1004 1
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0008 0.0009
Onchocerca volvulus 0.0034 0.0022 0.0041
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0004 0.0327
Echinococcus granulosus RUN 0.0039 0.0027 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Schistosoma mansoni rab6-interacting 0.0039 0.0027 0.0077
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.001 0.0011
Onchocerca volvulus 0.0015 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0179 0.0179 0.03
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0054 0.0044 0.0048
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0006 0.0007
Schistosoma mansoni adenoreceptor 0.0034 0.0022 0.0064
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0001 0.0003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0019 0.0032
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0005 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0004 0.0021
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0034 0.0022 0.0037
Brugia malayi cytochrome P450 0.0108 0.0101 0.017
Echinococcus granulosus protein tyrosine phosphatase n9 0.0037 0.0025 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0014 0.1321
Toxoplasma gondii cathepsin CPL 0.0028 0.0015 0.0015
Brugia malayi hypothetical protein 0.0054 0.0044 0.0073
Loa Loa (eye worm) cytochrome P450 family protein 0.0147 0.0144 0.0242
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0117 0.0112 0.0125
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0117 0.0112 0.0188
Brugia malayi hypothetical protein 0.0095 0.0087 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0076 0.0128
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0042 0.0128
Echinococcus granulosus carbonic anhydrase II 0.0942 0.1004 0.112
Onchocerca volvulus 0.0037 0.0025 0.0045
Echinococcus granulosus somatostatin receptor 0.0034 0.0022 0.0025
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0037 0.0025 0.0028
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0022 0.0064
Brugia malayi Probable ClpP-like protease 0.0077 0.0069 0.0115
Schistosoma mansoni hypothetical protein 0.0081 0.0073 0.021
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0016 0.0016
Echinococcus multilocularis somatostatin receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0108 0.0101 0.0995
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0034 0.0022 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0008
Loa Loa (eye worm) carbonic anhydrase 3 0.0942 0.1004 0.1686
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0117 0.0112 0.0321
Mycobacterium ulcerans oxidoreductase 0.0083 0.0074 0.0236
Schistosoma mansoni lipoxygenase 0.0232 0.0236 0.0675
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1451 0.1555 0.1734
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0108 0.0101 0.0326
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0027 0.003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0015 0.0016
Plasmodium falciparum importin beta, putative 0.0029 0.0016 0.0312
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.01 0.0093 0.0103
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0007 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0117
Echinococcus granulosus neuropeptide s receptor 0.0034 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Brugia malayi steroid hormone receptor 0.0179 0.0179 0.03
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0021
Brugia malayi Cytochrome P450 family protein 0.0108 0.0101 0.017
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.01 0.0093 0.0909
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0114 0.0191
Onchocerca volvulus Putative nachr subunit 0.0117 0.0112 0.0205
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0015 0.0016
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Echinococcus granulosus alpha 1A adrenergic receptor 0.0034 0.0022 0.0025
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0006 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0061 0.0192
Schistosoma mansoni zinc finger protein 0.0084 0.0076 0.0219
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0117 0.0112 0.0125
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0025 0.0042
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0037 0.0025 0.0071
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0022 0.0025
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.001 0.1271
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0041 0.0029 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.0179 0.0199
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0041 0.0029 0.0084
Entamoeba histolytica Ran family GTPase 0.0021 0.0008 0.0344
Loa Loa (eye worm) TYRA-2 protein 0.0034 0.0022 0.0037
Entamoeba histolytica G protein alpha subunit, putative 0.0022 0.0008 0.0367
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0007 0.0021
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0122 0.0396
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0014
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0007 0.0058
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0034 0.0022 0.0041
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0037 0.0025 0.0028
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0041 0.0029 0.0049
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0016 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.1673
Onchocerca volvulus Matrilysin homolog 0.2283 0.2455 0.4494
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.004 0.0121
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0008
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0061 0.0192
Brugia malayi Cathepsin L-like precursor 0.0028 0.0015 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0179 0.0179 0.03
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0064 0.0622
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0179 0.0179 0.03
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0014 0.0001 0.0001
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0006 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0022 0.0064
Loa Loa (eye worm) hypothetical protein 0.0099 0.0093 0.0155
Onchocerca volvulus 0.0037 0.0025 0.0045
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0037 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0108 0.0101 0.0291
Schistosoma mansoni tyrosine kinase 0.0247 0.0252 0.0723
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0076 0.0085
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0117 0.0112 0.0125
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.1673
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0041 0.0046
Schistosoma mansoni ankyrin 23/unc44 0.0014 0 0.0000000024985
Echinococcus granulosus lamin dm0 0.0026 0.0013 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0061 0.3052
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0117 0.0112 0.0125
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.024 0.0268
Onchocerca volvulus 0.0037 0.0025 0.0045
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0008 0.0008
Brugia malayi nuclear receptor NHR-88 0.0179 0.0179 0.03
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.01 0.0093 0.0909
Trypanosoma cruzi UDP-galactopyranose mutase 0.0083 0.0074 0.0726
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0039 0.0117
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0069 0.6097
Loa Loa (eye worm) RNA binding protein 0.0063 0.0053 0.0089
Echinococcus granulosus lysine specific histone demethylase 1A 0.0083 0.0074 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Echinococcus granulosus tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0001 0.0097
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0108 0.0101 0.0326
Onchocerca volvulus 0.0037 0.0025 0.0045
Brugia malayi Cytochrome P450 family protein 0.0116 0.0111 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0108 0.0101 0.0326
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0108 0.0101 0.0326
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0017 0.0019
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0041 0.0046
Onchocerca volvulus 0.0015 0.0001 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0064 0.0622
Brugia malayi Death domain containing protein 0.0014 0 0.0000000014626
Onchocerca volvulus 0.0026 0.0013 0.0024
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.0317 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) SRC-1 0.0014 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0054
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0037 0.0025 0.1202
Brugia malayi hypothetical protein 0.0037 0.0025 0.0042
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0274 0.0282 0.0314
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Echinococcus multilocularis protoporphyrinogen oxidase 0.0083 0.0074 0.0083
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0064 0.0622
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0001 0.009
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0014 0.0016
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0084 0.0076 0.0085
Schistosoma mansoni opsin-like receptor 0.0034 0.0022 0.0064
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0007 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0039 0.3475
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0213 0.0216 0.2135
Giardia lamblia Kinase, STE STE20 0.0087 0.008 1
Leishmania major cytochrome p450-like protein 0.0108 0.0101 0.0995
Echinococcus granulosus cysteine protease 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.03
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0037 0.0062
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0022 0.0025
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0041 0.0392
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0083 0.0074 0.0213
Trypanosoma cruzi cysteine proteinase, putative 0.002 0.0006 0.0046
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0014 0.0001 0.0001
Brugia malayi ecdysone receptor 0.0084 0.0076 0.0128
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0179 0.0179 0.0327
Echinococcus multilocularis cathepsin L 0.002 0.0006 0.0007
Trichomonas vaginalis STE family protein kinase 0.0087 0.008 1
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0083 0.0074 0.0083
Onchocerca volvulus 0.0034 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0058 0.0048 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0117 0.0112 0.0188
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0008
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0037 0.0025 0.1202
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0004 0.0056
Echinococcus granulosus glycine receptor subunit beta 0.0117 0.0112 0.0125
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0037 0.0025 0.0231
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0472
Brugia malayi hypothetical protein 0.0039 0.0027 0.0045
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Echinococcus multilocularis nuclear receptor nhr 48 0.0084 0.0076 0.0085
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0054
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0037 0.0025 0.0028
Onchocerca volvulus 0.0037 0.0025 0.0045
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0005 0.0035
Brugia malayi Tyrosine-protein kinase abl-1 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0117 0.0112 0.0205
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0179 0.0179 0.03
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.007
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0006
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0041 0.0392
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0006 0.001
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0053 0.0089
Schistosoma mansoni neurotransmitter gated ion channel 0.0054 0.0044 0.0125
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0037 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0006 0.0017
Schistosoma mansoni cpg binding protein 0.0125 0.0121 0.0345
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0042
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0083 0.0074 0.1523
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0081 0.0073 0.0081
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0179 0.0179 0.03
Plasmodium falciparum fructose-bisphosphate aldolase 0.01 0.0093 0.1905
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.1673
Brugia malayi Matrixin family protein 0.2283 0.2455 0.4121
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0918
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0001 0.0001
Brugia malayi PHD-finger family protein 0.0058 0.0048 0.008
Echinococcus granulosus importin subunit beta 1 0.0029 0.0016 0.0018
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0013 0.025
Echinococcus multilocularis dual specificity mitogen activated protein 0.0087 0.008 0.0089
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0007 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0016 0.0018
Brugia malayi hypothetical protein 0.007 0.006 0.0101
Brugia malayi hypothetical protein 0.0037 0.0025 0.0042
Onchocerca volvulus 0.0034 0.0022 0.0041
Schistosoma mansoni single-minded 0.0047 0.0036 0.0103
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0042 0.5577
Plasmodium falciparum thioredoxin reductase 0.005 0.0039 0.0791
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0037 0.0025 0.0071
Echinococcus multilocularis protein dispatched 1 0.0096 0.0089 0.01
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0095 0.0087 0.0097
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0108 0.0101 0.0326
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0054 0.0522
Schistosoma mansoni neuropeptide receptor 0.0034 0.0022 0.0064
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.0179 0.0199
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0022 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.0179 0.0199
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0054 0.0044 0.0073
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0006 0.001
Mycobacterium tuberculosis Conserved protein 0.0038 0.0026 0.0075
Loa Loa (eye worm) hypothetical protein 0.0084 0.0076 0.0128
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0103 0.0295
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2423 0.2606 0.2907
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0014 0.0041
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0001 0.0001
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0022 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0027 0.0014 0.0041
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0108 0.0101 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0749
Brugia malayi Bromodomain containing protein 0.0082 0.0074 0.0124
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0063 0.0053 0.0089
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0025 0.0042
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0008 0.1009
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0007 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0108 0.0101 0.0326
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.0106
Mycobacterium tuberculosis Conserved hypothetical protein 0.0083 0.0074 0.0236
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0037 0.0025 0.0071
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.1247
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0108 0.0101 0.0326
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0141
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0418 0.0437 0.1253
Onchocerca volvulus 0.0034 0.0022 0.0041
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0026 0.0075
Onchocerca volvulus 0.0117 0.0112 0.0205
Echinococcus multilocularis serotonin receptor 0.0034 0.0022 0.0025
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0081 0.0073 0.3622
Mycobacterium tuberculosis Possible oxidoreductase 0.0083 0.0074 0.0236
Leishmania major protein kinase, putative 0.0017 0.0003 0.0018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0179 0.0179 0.0512
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0117 0.0112 0.0125
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0087 0.008 0.0777
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.046 0.0482 0.081
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0593
Plasmodium falciparum thioredoxin reductase 0.0017 0.0004 0.0056
Brugia malayi hypothetical protein 0.0037 0.0025 0.0042
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0037 0.0025 0.0231
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0081 0.0073 0.0122
Schistosoma mansoni tyrosine kinase 0.0014 0.0001 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0078 0.007 0.0117
Onchocerca volvulus 0.0054 0.0044 0.008
Brugia malayi putative neuropeptide receptor 0.0034 0.0022 0.0037
Brugia malayi SWIRM domain containing protein 0.0083 0.0074 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0179 0.0179 0.03
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0179 0.0179 0.03
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0015 0.1821
Loa Loa (eye worm) hypothetical protein 0.0088 0.008 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0108 0.0101 0.0326
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0022 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.002 0.0006 0.0046
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0262
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0069 0.921
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0216 0.2135
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0026 0.0075
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0005 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.008 0.0072 0.008
Brugia malayi jmjC domain containing protein 0.0078 0.007 0.0117
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0007 0.0319
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.007 0.02
Echinococcus granulosus tm gpcr rhodopsin 0.0534 0.0563 0.0628
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0037 0.0025 0.0028
Echinococcus multilocularis epidermal growth factor receptor 0.0253 0.0259 0.0289
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0037 0.0025 0.0231
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0064 0.0622
Echinococcus granulosus cathepsin L cysteine proteinase 0.0028 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0064
Schistosoma mansoni opsin-like receptor 0.0034 0.0022 0.0064
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0083 0.0074 0.6612
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0198 1
Brugia malayi hypothetical protein 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Schistosoma mansoni amine GPCR 0.0034 0.0022 0.0064
Brugia malayi jmjC domain containing protein 0.0019 0.0005 0.0009
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0004 0.0432
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1451 0.1555 0.261
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0027 0.003
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0117 0.0112 0.0188
Plasmodium falciparum cysteine proteinase falcipain 3 0.0028 0.0015 0.0284
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0022 0.0025
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Brugia malayi hypothetical protein 0.0083 0.0074 0.0125
Schistosoma mansoni nAChR subunit 0.0117 0.0112 0.0321
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0061 0.0192
Brugia malayi conserved hypotetical protein 0.0084 0.0076 0.0128
Trichomonas vaginalis esterase, putative 0.0038 0.0026 0.3267
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0093 0.0103
Trypanosoma cruzi trans-sialidase, putative 0.0092 0.0085 0.0828
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0077 0.0085
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0001 0.0003
Echinococcus granulosus integrin beta 2 0.0331 0.0344 0.0383
Brugia malayi Integrin beta pat-3 precursor 0.045 0.0472 0.0792
Leishmania major cysteine peptidase A (CPA) 0.0028 0.0015 0.0131
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0042 0.0849
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0034 0.0022 0.0025
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0034 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0077 0.0069 0.0115
Echinococcus multilocularis integrin beta 2 0.0331 0.0344 0.0383
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0037 0.0025 0.0028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0179 0.0179 0.0199
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0041 0.0392
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0011
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.01 0.0093 0.0156
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0117 0.0112 0.0125
Brugia malayi neuropeptide F receptor 0.0034 0.0022 0.0037
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0037 0.0025 0.0028
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0022 0.0064
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0022 0.0025
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0005 0.0006
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0004 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0061 0.0192
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0037 0.0025 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0034 0.0022 0.0064
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0001 0.0001
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0092 0.0085 0.0828
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0008 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0004 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0179 0.0179 0.03
Trypanosoma brucei trans-sialidase 0.0092 0.0085 0.0828
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0111 0.0187
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0011
Echinococcus multilocularis nAChR subunit 0.0063 0.0053 0.0059
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0037 0.0025 0.0028
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0004 0.0006

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 18.7 uM Concentration required to stimulate binding of [35S]-GTP-gammaS, with G alpha i1 ChEMBL. 16190775
EC50 (functional) = 18.9 uM Concentration required to stimulate binding of [35S]-GTP-gammaS, with G alpha i3 ChEMBL. 16190775
EC50 (functional) = 19.3 uM Concentration required to stimulate binding of [35S]-GTP-gammaS, with G alpha o1 ChEMBL. 16190775
Stimulation (functional) = 420 % Percent stimulation of [35S]-GTP-gammaS, binding to G alpha o1 at 5E-5 M of basal for 30 minutes ChEMBL. 16190775
Stimulation (functional) = 435 % Percent stimulation of [35S]-GTP-gammaS, binding to G alpha i3 at 5E-5 M of basal for 30 minutes ChEMBL. 16190775
Stimulation (functional) = 704 % Percent stimulation of [35S]-GTP-gammaS, binding to G alpha i1 at 5E-5 M of basal for 30 minutes ChEMBL. 16190775

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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