Detailed information for compound 507485

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 525.125 | Formula: C30H41ClN4O2
  • H donors: 1 H acceptors: 2 LogP: 4.8 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCC(=O)N1CC[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccc(cc1[C@H](C(C)C)N)C)c1ccc(cc1)Cl
  • InChi: 1S/C30H41ClN4O2/c1-5-6-27(36)35-14-13-24(22-8-10-23(31)11-9-22)29(35)30(37)34-17-15-33(16-18-34)26-12-7-21(4)19-25(26)28(32)20(2)3/h7-12,19-20,24,28-29H,5-6,13-18,32H2,1-4H3/t24-,28+,29+/m1/s1
  • InChiKey: UMCBQPKLWYZBPK-MHZHKKNFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanocortin 4 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Treponema pallidum ribonuclease H (rnhA) 0.0022 0.0081 0.0126
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0387 0.1909
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0019 0.0168
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0053
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0058 0.0356 0.0356
Treponema pallidum sodium- and chloride- dependent transporter 0.0063 0.0396 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus granulosus tissue type plasminogen activator 0.0039 0.0209 0.0385
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0356 0.5992
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0024 0.0097 0.0476
Toxoplasma gondii kringle domain-containing protein 0.0039 0.0209 0.0786
Toxoplasma gondii orotate phosphoribosyltransferase 0.0021 0.0077 0.029
Loa Loa (eye worm) dehydrogenase 0.0024 0.0097 0.0097
Mycobacterium leprae TWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY) 0.0031 0.0151 0.1264
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0058 0.028
Loa Loa (eye worm) hypothetical protein 0.0063 0.0396 0.0396
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0024 0.0097 0.0476
Brugia malayi hypoxia-induced factor 1 0.0158 0.1107 0.1107
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0069 0.0436 0.3998
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0029 0.0139 0.022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0168 0.0168
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0233 0.1149
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0261
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0168 0.0313
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0021 0.0077 0.1285
Giardia lamblia Hypothetical protein 0.0024 0.0097 0.1622
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0115
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Loa Loa (eye worm) hypoxia-induced factor 1 0.0158 0.1107 0.1107
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0019 0.0168
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0058 0.0048
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0075 0.0075
Mycobacterium tuberculosis Probable two-component system transcriptional regulator 0.0031 0.0151 0.097
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0019 0.0089
Onchocerca volvulus 0.0024 0.0097 0.0586
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0078 0.0507 0.0507
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Trichomonas vaginalis receptor histidine kinase, putative 0.0031 0.0151 0.2421
Brugia malayi hypothetical protein 0.0024 0.0097 0.0097
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0097 0.0154
Echinococcus multilocularis musashi 0.0028 0.0132 0.0209
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0061 0.0115
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0095 0.0358
Brugia malayi CXXC zinc finger family protein 0.0029 0.014 0.014
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0181 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.028 0.2024 1
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.0097 0.0439
Plasmodium falciparum orotate phosphoribosyltransferase 0.0021 0.0077 0.1297
Schistosoma mansoni hypothetical protein 0.0035 0.0181 0.0338
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0024 0.0097 0.0476
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Onchocerca volvulus 0.0023 0.0095 0.0574
Onchocerca volvulus 0.009 0.0594 0.3584
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0021 0.0077 0.0241
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0058 0.0048
Leishmania major oxidoreductase-like protein 0.0024 0.0097 0.0476
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Echinococcus granulosus RUN 0.0021 0.0075 0.0138
Echinococcus granulosus ribonuclease H1 0.0022 0.0081 0.0149
Onchocerca volvulus 0.002 0.0069 0.0418
Mycobacterium leprae Probable two-component system transcriptional regulator 0.0031 0.0151 0.1264
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Mycobacterium ulcerans two component sensory transduction protein RegX3 0.0031 0.0151 0.2526
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0183 0.42
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0032 0.0051
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.014 0.014
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0077 0.0241
Schistosoma mansoni organic anion transporter 0.0029 0.0139 0.0259
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Toxoplasma gondii PAN/Apple domain-containing protein 0.0023 0.0095 0.0358
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0078 0.0507 0.0945
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.0097 0.0154
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Schistosoma mansoni sensor histidine kinase/response regulator 0.0031 0.0151 0.0281
Mycobacterium ulcerans oxidoreductase 0.0024 0.0097 0.1622
Brugia malayi Cytochrome P450 family protein 0.0018 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Trichomonas vaginalis ribonuclease H1, putative 0.0022 0.0081 0.1232
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 1
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0061 0.0061
Schistosoma mansoni cytochrome P450 0.0018 0.0058 0.0107
Loa Loa (eye worm) hypothetical protein 0.0045 0.0258 0.0258
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0029 0.0139 0.0139
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0851 0.6318 1
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0024 0.0097 0.0181
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0356 0.0563
Schistosoma mansoni nuclear receptor 0.0033 0.0168 0.0313
Mycobacterium tuberculosis Conserved hypothetical protein 0.0152 0.1062 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Schistosoma mansoni hypothetical protein 0.0069 0.0437 0.0815
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0151 0.0745
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Brugia malayi hypothetical protein 0.0024 0.0097 0.0097
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0024 0.0097 0.0097
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.008 0.0519 0.2563
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0063 0.0396 0.0396
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0018 0.0053 0.0748
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0181 0.0338
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0053 0.0875
Onchocerca volvulus 0.0023 0.0095 0.0574
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0147 0.1026 0.1891
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0419 0.0663
Mycobacterium ulcerans two component transcriptional regulator 0.0031 0.0151 0.2526
Toxoplasma gondii PAN domain-containing protein 0.0364 0.2654 1
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0095 0.0464
Echinococcus multilocularis ecdysone induced protein 78C 0.0078 0.0507 0.0803
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0019 0.0089
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.008 0.0519 0.0968
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Schistosoma mansoni lipoxygenase 0.0021 0.0075 0.0139
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0024 0.0097 0.0439
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0075 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0063 0.0396 0.0396
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0031 0.0151 0.2421
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0114 0.1923
Brugia malayi ecdysteroid receptor 0.0231 0.1657 0.1657
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0677 0.0677
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0078 0.0507 0.0803
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Trypanosoma brucei oxidoreductase-like protein 0.0024 0.0097 0.0476
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0024 0.0097 0.0476
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0033 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Schistosoma mansoni lamin 0.0028 0.0132 0.0246
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0183 0.1287
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0101 0.0677 0.0677
Echinococcus granulosus Solute carrier organic anion transporter family 0.0029 0.0139 0.0256
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0024 0.0097 0.0439
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Echinococcus multilocularis RUN 0.0021 0.0075 0.0118
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0356 0.0563
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0168 0.0313
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 0.7066
Toxoplasma gondii microneme protein MIC4 0.0023 0.0095 0.0358
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0024 0.0097 0.0179
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0075 0.0138
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0061 0.0115
Echinococcus granulosus adenine phosphoribosyltransferase 0.0021 0.0077 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Brugia malayi RNase H family protein 0.0022 0.0081 0.0081
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0067 0.0422 0.2083
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0024 0.0097 0.1622
Toxoplasma gondii protease inhibitor PI2 0.002 0.0069 0.0261
Brugia malayi hypothetical protein 0.0422 0.3089 0.3089
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0067 0.0422 0.1591
Schistosoma mansoni hypothetical protein 0.0032 0.0159 0.0296
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0058 0.0957
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0337 0.127
Schistosoma mansoni inositol monophosphatase 0.0039 0.021 0.0392
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium ulcerans two component regulator receiver domain-containing protein 0.0031 0.0151 0.2526
Schistosoma mansoni DNA polymerase eta 0.0035 0.0183 0.034
Echinococcus multilocularis lamin 0.0028 0.0132 0.0209
Echinococcus granulosus expressed protein 0.0369 0.2693 0.4965
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0075 0.0138
Schistosoma mansoni hypothetical protein 0.0507 0.3732 0.6957
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0355 0.0654
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0078 0.0507 0.0935
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0058 0.0356 0.0356
Trichomonas vaginalis steroid dehydrogenase, putative 0.0024 0.0097 0.1505
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 0.7066
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0476
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.008 0.0519 0.4623
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0183 0.0183
Onchocerca volvulus 0.0023 0.0095 0.0574
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.127
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.2931
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Trypanosoma brucei unspecified product 0.0024 0.0101 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0078 0.0507 0.0507
Schistosoma mansoni lipoxygenase 0.0058 0.0355 0.0661
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0007 0.001
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Brugia malayi hypothetical protein 0.0018 0.0053 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.0078 0.0507 0.0507
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0168 0.0168
Toxoplasma gondii hypothetical protein 0.0023 0.0095 0.0358
Leishmania major DNA polymerase eta, putative 0.0035 0.0183 0.0898
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0024 0.0097 0.0366
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0095 0.0358
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.021 1
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0029 0.0139 0.022
Echinococcus granulosus hypothetical protein 0.0024 0.0097 0.0179
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0031 0.0151 0.2421
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0019 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Echinococcus multilocularis tissue type plasminogen activator 0.0039 0.0209 0.033
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0033 0.0033
Brugia malayi translation initiation factor 4E 0.0067 0.0422 0.0422
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0356 0.593
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0058 0.0048
Echinococcus multilocularis ribonuclease H1 0.0022 0.0081 0.0128
Brugia malayi tailless protein 0.0033 0.0168 0.0168
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0061 0.0115
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.2931
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0095 0.0095
Echinococcus multilocularis FTZ F1 alpha 0.0078 0.0507 0.0803
Plasmodium vivax phosphodiesterase gamma, putative 0.0058 0.0356 0.3469
Schistosoma mansoni intermediate filament proteins 0.0028 0.0132 0.0246
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0058 0.0356 0.0663
Loa Loa (eye worm) agrin synaptic family protein 0.002 0.0069 0.0069
Brugia malayi Inositol-1 0.0039 0.021 0.021
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0168 0.0168
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.018 0.1261
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0058 0.0106
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0097 0.213
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.021 0.0793
Onchocerca volvulus 0.0024 0.0097 0.0586
Brugia malayi Cytochrome P450 family protein 0.0028 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0054 0.0327 0.061
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0097 0.0946
Giardia lamblia Reductase, putative 0.0024 0.0097 0.1622
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0356 0.593
Schistosoma mansoni loxhd1 0.0021 0.0075 0.0139
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0147 0.1026 0.5065
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.021 0.0333
Brugia malayi Sulfatase family protein 0.0018 0.0053 0.0053
Mycobacterium tuberculosis Two component transcriptional regulator TrcR 0.0031 0.0151 0.097
Toxoplasma gondii hypothetical protein 0.0023 0.0095 0.0358
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0356 0.0656
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0078 0.0507 0.0507
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0021 0.0077 0.0077
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0127 0.0622
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.021 0.3446
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0058 0.0048
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0058 0.0356 0.0356
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0024 0.0097 0.0476
Onchocerca volvulus 0.0028 0.0132 0.0796
Echinococcus multilocularis lamin dm0 0.0028 0.0132 0.0209
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.021 0.3446
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 0.2931
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Trichomonas vaginalis sensor histidine kinase, putative 0.0031 0.0151 0.2421
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Brugia malayi Nuclear hormone receptor-like 1 0.0078 0.0507 0.0507
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0147 0.1026 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0032 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0387 0.1909
Schistosoma mansoni cell polarity protein 0.0025 0.0109 0.0203
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0078 0.0507 0.0945
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0097 0.1622
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0075 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0356 0.5992
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0097 0.213
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0209 0.1027
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0063 0.0396 0.0396
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0078 0.0507 0.0935
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0109
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0061 0.0115
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0058 0.0957
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0022 0.0034
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0023 0.0095 0.0464
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0021 0.0077 0.0144
Echinococcus granulosus agrin 0.002 0.0069 0.0128
Echinococcus multilocularis pikachurin 0.0025 0.0109 0.0172
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0356 0.1755
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0114
Mycobacterium leprae Probable oxidoreductase 0.0024 0.0097 0.075
Onchocerca volvulus 0.0023 0.0095 0.0574
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0168 0.031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Brugia malayi Protein kinase domain containing protein 0.0039 0.0209 0.0209
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0024 0.0097 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0078 0.0507 0.0507
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0018 0.0053 0.0748
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0024 0.0097 0.0097
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Onchocerca volvulus 0.0023 0.0095 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0356 0.0356
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0089 0.0587 0.989
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Giardia lamblia Ribonuclease H 0.0022 0.0081 0.1353
Leishmania major short chain dehydrogenase/reductase, putative 0.0024 0.0097 0.0476
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0061 0.0113
Onchocerca volvulus 0.0024 0.0097 0.0586
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0053
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0021 0.0077 0.0377
Leishmania major short chain dehydrogenase, putative 0.0024 0.0097 0.0476
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0001 0.0003
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0021 0.0077 0.1163
Brugia malayi cytochrome P450 0.0018 0.0058 0.0058
Brugia malayi Retinol dehydrogenase 12 0.0024 0.0097 0.0097
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0081 0.0396
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0019 0.0089
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0151 0.0745
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0058 0.028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Giardia lamblia Hypothetical protein 0.0058 0.0356 0.5986
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0419 0.0419
Onchocerca volvulus 0.0033 0.0168 0.1015
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Trichomonas vaginalis receptor histidine kinase, putative 0.0031 0.0151 0.2421
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0233 0.1149
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0097 0.213
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0341 0.0341
Loa Loa (eye worm) RecQ helicase 0.0022 0.0087 0.0087
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0132 0.0132
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0024 0.0097 0.0439
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0067 0.0422 0.0787
Brugia malayi ecdysone receptor 0.0033 0.0168 0.0168
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0419 0.0419
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0032 0.006
Brugia malayi hypothetical protein 0.0045 0.0258 0.0258
Trypanosoma brucei unspecified product 0.0055 0.0336 0.1658
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0067 0.1128
Mycobacterium tuberculosis Probable two component transcriptional regulatory protein TcrX 0.0031 0.0151 0.097
Mycobacterium ulcerans two component response transcriptional regulatory protein PrrA 0.0031 0.0151 0.2526
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0061 0.0113
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0019 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0021 0.0077 0.0558
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0419 0.0781
Onchocerca volvulus 0.0024 0.0097 0.0586
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0019 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0019 0.0168
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0115
Brugia malayi RNase H family protein 0.0022 0.0081 0.0081
Entamoeba histolytica short chain dehydrogenase family protein 0.0024 0.0097 0.213
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0061 0.0097
Schistosoma mansoni cpg binding protein 0.0029 0.014 0.026
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0058 0.0957
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0356 0.1755
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0021 0.0077 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Brugia malayi intermediate filament protein 0.0028 0.0132 0.0132
Brugia malayi nuclear receptor NHR-67 0.0033 0.0168 0.0168
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0058 0.0957
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Brugia malayi hypothetical protein 0.0019 0.0061 0.0061
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.5992
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0356 0.0656
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0058 0.0957
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0018 0.0053 0.0318
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.009 0.0594 0.1095
Onchocerca volvulus 0.0039 0.0209 0.1259
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Brugia malayi nuclear receptor RXR 0.0045 0.0258 0.0258
Mycobacterium ulcerans dehydrogenase 0.0024 0.0097 0.1622
Plasmodium falciparum phosphodiesterase gamma, putative 0.0058 0.0356 0.5992
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0058 0.0048
Schistosoma mansoni agrin 0.002 0.0069 0.0129
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0061 0.0061
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0097 0.0476
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0097 0.1622
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0019 0.0035
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0021 0.0077 0.0241
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0058 0.0957
Brugia malayi PXA domain containing protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) norepinephrine transporter 0.0063 0.0396 0.0396
Brugia malayi Kringle domain containing protein 0.0039 0.0209 0.0209
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.0507 0.0803
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0095 0.0464
Onchocerca volvulus 0.0078 0.0507 0.3061
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0356 0.1755
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Leishmania major protein kinase, putative 0.0013 0.0019 0.0089
Schistosoma mansoni microtubule-associated protein tau 0.0724 0.5365 1
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.0097 0.0586
Schistosoma mansoni cpg binding protein 0.0031 0.0152 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Leishmania major adenine phosphoribosyltransferase 0.0021 0.0077 0.0377
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0024 0.0097 0.0154
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 0.2931
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Schistosoma mansoni uracil phosphoribosyltransferase 0.0021 0.0077 0.0144
Brugia malayi nuclear hormone receptor 0.0033 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0115
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0078 0.0507 0.0945
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Leishmania major cAMP-specific phosphodiesterase, putative 0.028 0.2024 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.021 0.3536
Schistosoma mansoni hypothetical protein 0.0012 0.0007 0.0012
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0159 0.0159
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0181 0.0334
Echinococcus granulosus hypothetical protein 0.0024 0.0097 0.0179
Echinococcus granulosus WW domain containing oxidoreductase 0.0024 0.0097 0.0179
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0061 0.0061
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.028 0.2024 1
Brugia malayi RNA binding protein 0.0066 0.0419 0.0419
Onchocerca volvulus 0.0021 0.0075 0.045
Mycobacterium ulcerans arylsulfatase, AslA 0.0018 0.0053 0.0875
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.0097 0.0179
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Schistosoma mansoni thyroid hormone receptor 0.0078 0.0507 0.0945
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Mycobacterium ulcerans two component sensory transduction transcriptional regulatory protein MtrA 0.0031 0.0151 0.2526
Brugia malayi hypothetical protein 0.0029 0.0139 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0058 0.0048
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0109 0.0203
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Schistosoma mansoni polycystin 1-related 0.0021 0.0075 0.0139
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Loa Loa (eye worm) inositol-1 0.0039 0.021 0.021
Giardia lamblia Hypothetical protein 0.0018 0.0053 0.0875
Echinococcus multilocularis retinol dehydrogenase 13 0.0024 0.0097 0.0154
Leishmania major hypothetical protein, conserved 0.0058 0.0356 0.1755
Mycobacterium tuberculosis Two component response transcriptional regulatory protein PrrA 0.0031 0.0151 0.097
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Loa Loa (eye worm) hypothetical protein 0.134 1 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0183 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Onchocerca volvulus 0.0024 0.0097 0.0586
Echinococcus granulosus dnaJ subfamily B 0.0418 0.3062 0.5646
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0053
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0061 0.0097
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0109 0.0201
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0024 0.0097 0.075
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.009 0.0594 1
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0024 0.0097 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.127
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.0097 0.0439
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Treponema pallidum protein-glutamate methylesterase (cheB) 0.0031 0.0151 0.2306
Mycobacterium leprae conserved hypothetical protein 0.0152 0.1062 1
Brugia malayi Dehydrogenases, short chain protein 30 0.0024 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Brugia malayi hypothetical protein 0.0033 0.0168 0.0168
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0024 0.0097 0.0476
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Mycobacterium tuberculosis Conserved protein 0.0021 0.0077 0.0241
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0058 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Schistosoma mansoni hypothetical protein 0.0032 0.0159 0.0296
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0025 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0187 0.1326 0.2471
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0203 0.3412
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus granulosus tar DNA binding protein 0.0066 0.0419 0.0772
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Onchocerca volvulus 0.0023 0.0095 0.0574
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0018
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0168 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0058 0.0048
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0033 0.0321
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0061 0.0113
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0168 0.0168
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0168 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0168 0.0266
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0019
Echinococcus granulosus death domain containing protein 0.0015 0.0032 0.006
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0025 0.0109 0.0203
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Brugia malayi Death domain containing protein 0.0015 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0018 0.0058 0.0107
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0303 0.0565
Plasmodium falciparum cysteine repeat modular protein 1 0.0039 0.0209 0.3514
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0058 0.0356 0.0656
Echinococcus multilocularis microtubule associated protein 2 0.0724 0.5365 0.8491
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0366
Echinococcus granulosus serotonin transporter 0.0063 0.0396 0.073
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0058 0.0356 0.0563
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0127 0.0127
Echinococcus granulosus lamin dm0 0.0028 0.0132 0.0243
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0021 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0151 0.0745
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0061 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Echinococcus multilocularis geminin 0.0507 0.3732 0.5907
Mycobacterium leprae putative cytochrome p450 0.0018 0.0058 0.0372
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0078 0.0507 0.0507
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0061 0.0061
Onchocerca volvulus 0.0029 0.0139 0.0839
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0061 0.0115
Onchocerca volvulus 0.0021 0.0075 0.045
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0024 0.0097 0.0439
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0258 0.0408
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0366
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0024 0.0097 0.0586
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0115
Brugia malayi secreted modular calcium-binding protein 1 0.002 0.0069 0.0069
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Schistosoma mansoni nuclear receptor 0.0033 0.0168 0.0313
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Entamoeba histolytica hypothetical protein 0.0035 0.0181 0.4171
Trypanosoma brucei unspecified product 0.0024 0.0101 0.0494
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0061 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Mycobacterium ulcerans dehydrogenase/reductase 0.0024 0.0097 0.1622
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0476
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.021 0.1037
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Giardia lamblia Adenine phosphoribosyltransferase 0.0021 0.0077 0.1285
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.5992
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0258 0.0481
Echinococcus granulosus dna polymerase kappa 0.0062 0.0387 0.0713
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0019 0.0089
Brugia malayi Uncoordinated protein 44 0.0015 0.0032 0.0032
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0058 0.028
Leishmania major cytochrome p450-like protein 0.0018 0.0058 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0061 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0024 0.0097 0.0154
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0033
Onchocerca volvulus Bile acid receptor homolog 0.0231 0.1657 1
Brugia malayi steroid hormone receptor 0.0078 0.0507 0.0507
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0024 0.0097 0.1634
Leishmania major dehydrogenase-like protein 0.0024 0.0097 0.0476
Echinococcus granulosus uridine 5' monophosphate synthase 0.0021 0.0077 0.0142
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0078 0.0507 0.0803
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0061 0.0097
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.0045 0.0258 0.0258
Mycobacterium ulcerans sulfatase 0.0018 0.0053 0.0875
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0021 0.0077 0.0144
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.0075
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0024 0.0097 0.075
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0336 0.1658
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0387 0.0612
Leishmania major 3-keto-dihydrosphingosine reductase 0.0024 0.0097 0.0476
Brugia malayi Cytochrome P450 family protein 0.0028 0.0127 0.0127
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0168 0.0266
Mycobacterium tuberculosis Two component sensory transduction transcriptional regulatory protein MtrA 0.0031 0.0151 0.097
Echinococcus multilocularis 0.0018 0.0058 0.0091
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0067 0.0422 0.2083
Leishmania major short chain dehydrogenase, putative 0.0024 0.0097 0.0476
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.05 0.0792
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0097 0.0179
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0061 0.0097
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0078 0.0507 0.0945
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Treponema pallidum response regulatory protein (atoC) 0.0031 0.0151 0.2306
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 1
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0147 0.1026 0.5065
Trypanosoma cruzi short chain dehydrogenase, putative 0.0024 0.0097 0.0476
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0032 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0045 0.0258 0.0258
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Echinococcus multilocularis expressed protein 0.002 0.0069 0.011
Toxoplasma gondii oxidoreductase, putative 0.0024 0.0097 0.0366
Trypanosoma brucei DNA polymerase eta, putative 0.0035 0.0183 0.0898
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0356 0.0356
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0019 0.003
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Onchocerca volvulus 0.0063 0.0396 0.239
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.0097 0.0154
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0356 0.593
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0078 0.0507 0.0507
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.008 0.0519 0.8743
Schistosoma mansoni carbonyl reductase 0.0024 0.0097 0.0181
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0032 0.0061
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.008 0.0519 0.0519
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0677 0.0677
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0139 0.0139
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.009 0.0594 0.094
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0258 0.0476
Echinococcus granulosus hypothetical protein 0.0732 0.5424 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0139 0.0139
Echinococcus multilocularis oxidoreductase 0.0024 0.0097 0.0154
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 0.7066
Echinococcus multilocularis agrin 0.002 0.0069 0.011
Onchocerca volvulus 0.0023 0.0095 0.0574
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0159 0.0252
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Leishmania major hypothetical protein, conserved 0.0039 0.0209 0.1027
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Echinococcus granulosus FTZ F1 alpha 0.0078 0.0507 0.0935
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0024 0.0097 0.0439
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0097 0.0439
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0356 0.1755
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Loa Loa (eye worm) hypothetical protein 0.0014 0.0022 0.0022
Leishmania major xanthine phosphoribosyltransferase 0.009 0.0594 0.2931
Schistosoma mansoni cpg binding protein 0.0031 0.0152 0.0284
Loa Loa (eye worm) TK/ROR protein kinase 0.0039 0.0209 0.0209
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0097 0.0154
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Entamoeba histolytica hypothetical protein 0.0024 0.0097 0.213
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0168 0.031
Onchocerca volvulus 0.0033 0.0168 0.1015
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.009 0.0594 0.2238
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Schistosoma mansoni organic anion transporter 0.0029 0.0139 0.0259
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0024 0.0097 0.0476
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0024 0.0097 0.0439
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0087 0.0138
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0021 0.0077 0.0241
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0419 0.0419
Leishmania major short chain dehydrogenase/reductase, putative 0.0024 0.0097 0.0476
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.0231 0.1657 0.1657
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0078 0.0507 0.0803
Echinococcus granulosus follistatin 0.002 0.0069 0.0128
Entamoeba histolytica hypothetical protein 0.0035 0.0181 0.4171
Mycobacterium tuberculosis Probable dehydrogenase 0.0024 0.0097 0.0439
Echinococcus multilocularis conserved hypothetical protein 0.0024 0.0097 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Mycobacterium tuberculosis Conserved hypothetical protein 0.0152 0.1062 1
Loa Loa (eye worm) serotonin transporter b 0.0063 0.0396 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.0075
Onchocerca volvulus 0.0024 0.0097 0.0586
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.009 0.0594 0.1095
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0078 0.0507 0.0945
Brugia malayi PXA domain containing protein 0.0019 0.0061 0.0061
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0159 0.0293
Brugia malayi TAR-binding protein 0.0066 0.0419 0.0419
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.579
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0366
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0058 0.0957
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0024 0.0097 0.0476
Schistosoma mansoni hypothetical protein 0.0507 0.3732 0.6957
Brugia malayi SPARC precursor 0.002 0.0069 0.0069
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0061 0.0113
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0058 0.0048
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0024 0.0097 0.075
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium ulcerans short-chain type oxidoreductase 0.0024 0.0097 0.1622
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0029 0.0139 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0419 0.0781
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0168 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 0.7066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.0507 0.0935
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0356 0.1755
Brugia malayi prostaglandin transporter 0.0029 0.0139 0.0139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0078 0.0507 0.0935
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0061 0.0097
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0127 0.2123
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0078 0.0507 0.0507
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0061 0.0097
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Leishmania major eukaryotic translation initiation factor-like protein 0.0067 0.0422 0.2083
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0058 0.0048
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0052 0.0194
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0476
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0061 0.0113
Schistosoma mansoni zinc finger protein 0.0033 0.0168 0.0313
Echinococcus granulosus cpg binding protein 0.0031 0.0152 0.0281
Echinococcus granulosus slit 2 protein 0.0025 0.0109 0.0201
Schistosoma mansoni hypothetical protein 0.0039 0.0209 0.0389
Brugia malayi nuclear receptor NHR-88 0.0078 0.0507 0.0507
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0258 0.0258
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0032 0.006
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0183 0.0183
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0024 0.0097 0.0476
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.021 0.1037
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0058 0.0356 0.0356
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0132 0.0132
Echinococcus granulosus intermediate filament protein 0.0028 0.0132 0.0243
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans hypothetical protein 0.0021 0.0077 0.1285
Mycobacterium tuberculosis Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) 0.0031 0.0151 0.097
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0139 0.0139
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Brugia malayi hypothetical protein 0.0017 0.0045 0.0045
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.3469
Brugia malayi oxidoreductase 0.0024 0.0097 0.0097
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0075 0.0728
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0168 0.0313
Schistosoma mansoni slit 0.0025 0.0109 0.0203
Schistosoma mansoni carbonyl reductase 0.0024 0.0097 0.0181
Echinococcus granulosus single minded 2 0.0038 0.0203 0.0375
Trypanosoma brucei ribonuclease H1 0.0022 0.0081 0.0396
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0024 0.0097 0.0476
Schistosoma mansoni phosphoglucomutase 0.0022 0.0081 0.0151
Leishmania major protein kinase, putative 0.0013 0.0019 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0058 0.0048
Brugia malayi dehydrogenases, short chain protein 2 0.0024 0.0097 0.0097
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0061 0.0097
Schistosoma mansoni hypothetical protein 0.0021 0.0075 0.0139
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0168 0.1015
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.3469
Trypanosoma cruzi ribonuclease H1, putative 0.0022 0.0081 0.0396
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 0.2931
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0067 0.0422 0.2083
Echinococcus granulosus steroid dehydrogenase 0.0024 0.0097 0.0179
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.0507 0.0935
Leishmania major eukaryotic translation initiation factor-like 0.0067 0.0422 0.2083
Loa Loa (eye worm) hypothetical protein 0.0058 0.0356 0.0356
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.009 0.0594 0.094
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0095 0.0358
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0032 0.0032
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0147 0.1026 0.3864
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0058 0.0957
Toxoplasma gondii microneme protein, putative 0.0023 0.0095 0.0358
Mycobacterium ulcerans oxidoreductase 0.0024 0.0097 0.1622
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Mycobacterium ulcerans hydrolase 0.0018 0.0053 0.0875
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0095 0.0095
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Onchocerca volvulus 0.0029 0.0139 0.0839
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0061 0.0113
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0018
Echinococcus multilocularis slit 2 protein 0.0025 0.0109 0.0172
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0097 0.1622
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Onchocerca volvulus Ribonuclease H1 homolog 0.0022 0.0081 0.0489
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0114 0.056
Echinococcus granulosus GPCR family 2 0.0032 0.0159 0.0293
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0024 0.0097 0.0179
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0058 0.0356 0.0563
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0021 0.0077 0.0122
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0021 0.0077 0.0465
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.008 0.0519 0.0822
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium ulcerans carveol-like dehydrogenase 0.0024 0.0097 0.1622
Onchocerca volvulus 0.0013 0.0019 0.0113
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0168 0.0266
Mycobacterium ulcerans two component response transcriptional regulatory protein MprA 0.0031 0.0151 0.2526
Brugia malayi Protein kinase domain containing protein 0.0015 0.0032 0.0032
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0031 0.0151 0.2526
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0024 0.0097 0.0476
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.2931
Onchocerca volvulus 0.0029 0.0139 0.0839
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0078 0.0507 0.0935
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0677 0.0677
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0031 0.0151 0.097
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0058 0.028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Mycobacterium ulcerans arylsulfatase AtsB 0.0018 0.0053 0.0875
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0205 0.101
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Schistosoma mansoni inositol monophosphatase 0.0039 0.021 0.0392
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Schistosoma mansoni carbonyl reductase 0.0024 0.0097 0.0181
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0078 0.0507 0.0935
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0087 0.1341
Mycobacterium tuberculosis Possible two component system response transcriptional positive regulator PhoP 0.0031 0.0151 0.097
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0058 0.0356 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0115
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0097 0.1622
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0075 0.0118
Echinococcus multilocularis expressed protein 0.0369 0.2693 0.4262
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0387 0.6462
Chlamydia trachomatis two component regulatory system response regulator/ATPase 0.0031 0.0151 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Schistosoma mansoni rab6-interacting 0.0021 0.0075 0.0139
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0258 0.0258
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0024 0.0097 0.0476
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0078 0.0507 0.0507
Mycobacterium ulcerans two component transcriptional regulatory protein TcrX 0.0031 0.0151 0.2526
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Loa Loa (eye worm) solute carrier family 6 member 4 0.0063 0.0396 0.0396
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0019 0.0168
Onchocerca volvulus 0.0024 0.0097 0.0586
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0205
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.008 0.0519 0.8743
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0021 0.0077 0.0122
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0387 0.6462
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0058 0.0957
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0476
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0261
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0168 0.0266
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0366
Onchocerca volvulus 0.0024 0.0097 0.0586
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0058 0.0048
Mycobacterium ulcerans two component transcriptional regulator TrcR 0.0031 0.0151 0.2526
Leishmania major cytochrome p450-like protein 0.0028 0.0127 0.0622
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0061 0.0061
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0024 0.0097 0.0181
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.05 0.0922
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Schistosoma mansoni coup transcription factor 0.0078 0.0507 0.0945
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0139 0.0524
Schistosoma mansoni sodium/chloride dependent transporter 0.0063 0.0396 0.0738
Loa Loa (eye worm) RNA binding protein 0.0066 0.0419 0.0419
Toxoplasma gondii microneme protein MIC17C 0.0023 0.0095 0.0358
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0087 0.1341
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0419 0.0781
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0058 0.0957
Mycobacterium ulcerans two component transcriptional regulator 0.0031 0.0151 0.2526
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0024 0.0097 0.1622
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0097 0.0476
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Echinococcus granulosus oxidoreductase 0.0024 0.0097 0.0179
Brugia malayi hypothetical protein 0.0033 0.0168 0.0168
Echinococcus multilocularis thyroid hormone receptor alpha 0.0078 0.0507 0.0803
Brugia malayi hypothetical protein 0.0026 0.0114 0.0114
Onchocerca volvulus 0.0024 0.0097 0.0586
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0058 0.0356 0.5986
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0022 0.0081 0.03
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0058 0.0957
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0183 0.0183
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.1755
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0024 0.0097 0.0366
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0168 0.1015
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0078 0.0507 0.0803
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0067 0.0422 0.0778
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0127 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0021 0.0077 0.1285
Loa Loa (eye worm) hypothetical protein 0.1282 0.9563 0.9563
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0058 0.0957
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0019 0.003
Mycobacterium ulcerans hypothetical protein 0.0031 0.0151 0.2526
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0058 0.0048
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0058 0.0217
Onchocerca volvulus 0.0023 0.0095 0.0574
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0203 0.0322
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0114 0.043
Onchocerca volvulus 0.0038 0.0203 0.1226
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Trypanosoma cruzi short chain dehydrogenase, putative 0.0024 0.0097 0.0476
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0052 0.0097
Plasmodium vivax steroid dehydrogenase, putative 0.0024 0.0097 0.0946
Trypanosoma cruzi MFS transporter, putative 0.0029 0.0139 0.0683
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0024 0.0097 0.0439
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0058 0.0356 0.0656
Brugia malayi Phosphoribosyl transferase domain containing protein 0.009 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0045 0.0258 0.0258
Schistosoma mansoni lamin 0.0028 0.0132 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Brugia malayi hypothetical protein 0.0019 0.0061 0.0061
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0024 0.0097 0.213
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0183 0.0337
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0139 0.0839
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0109
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0023 0.0095 0.0358
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0058 0.028
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0097 0.1505
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0356 0.593
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0058 0.0048
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Toxoplasma gondii PAN domain-containing protein 0.0023 0.0095 0.0358
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0078 0.0507 0.0507
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0355 0.0561
Wolbachia endosymbiont of Brugia malayi response regulator PleD 0.0031 0.0151 0.5512
Brugia malayi orotate phosphoribosyltransferase family protein 0.0021 0.0077 0.0077
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0019 0.0168
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0114 0.1923
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0419 0.0781
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0095 0.0095
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0019 0.0168
Echinococcus granulosus bloom syndrome protein 0.0022 0.0087 0.0161
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0078 0.0507 0.3061
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0019 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0058 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0078 0.0507 0.0507
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0058 0.0957
Echinococcus granulosus microtubule associated protein 2 0.0724 0.5365 0.9891
Brugia malayi EGF-like domain containing protein 0.0025 0.0109 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0205 0.101
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0097 0.0476
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0097 0.0154
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0159 0.0293
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Brugia malayi Adenine phosphoribosyltransferase 0.0021 0.0077 0.0077
Onchocerca volvulus Protein ultraspiracle homolog 0.0078 0.0507 0.3061
Brugia malayi nuclear hormone receptor 0.0078 0.0507 0.0507
Onchocerca volvulus 0.0023 0.0095 0.0574
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus granulosus dna polymerase eta 0.0035 0.0183 0.0337
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0097 0.0439
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0061 0.0097
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.1755
Schistosoma mansoni steroid hormone receptor ad4bp 0.0078 0.0507 0.0945
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0032 0.0119
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0019 0.0035
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0097 0.0154
Trypanosoma brucei RNA helicase, putative 0.0187 0.1326 0.655
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0147 0.1026 0.1026
Leishmania major pteridine reductase 1 0.0024 0.0097 0.0476
Schistosoma mansoni hypothetical protein 0.0015 0.0032 0.0061
Toxoplasma gondii carbonyl reductase 1, putative 0.0024 0.0097 0.0366
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Leishmania major hypothetical protein, conserved 0.0024 0.0097 0.0476
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0095 0.0464
Brugia malayi hypothetical protein 0.0029 0.0139 0.0139
Loa Loa (eye worm) DR-78 0.0033 0.0168 0.0168
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0419 0.0781
Onchocerca volvulus 0.0023 0.0095 0.0574
Loa Loa (eye worm) hypothetical protein 0.0028 0.0132 0.0132
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0127 0.0127
Mycobacterium tuberculosis Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family) 0.0031 0.0151 0.097
Giardia lamblia Short-chain dehydrogenase, putative 0.0024 0.0097 0.1622
Echinococcus multilocularis follistatin 0.002 0.0069 0.011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Onchocerca volvulus 0.0029 0.0139 0.0839
Schistosoma mansoni single-minded 0.0051 0.0303 0.0565
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Two component DNA binding transcriptional regulatory protein TcrA 0.0031 0.0151 0.097
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.0097 0.0154
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0031 0.0151 0.2526
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0024 0.0097 0.0476
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0087 0.0087
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0147 0.1026 0.1623
Brugia malayi hypothetical protein 0.0021 0.0075 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0356 0.1755
Schistosoma mansoni RAR-like nuclear receptor 0.0078 0.0507 0.0945
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0114 0.1113
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Entamoeba histolytica hypothetical protein 0.0035 0.0181 0.4171
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0061 0.0113
Schistosoma mansoni nuclear hormone receptor 0.0078 0.0507 0.0945
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0058 0.0372
Plasmodium falciparum steroid dehydrogenase, putative 0.0024 0.0097 0.1634
Echinococcus granulosus geminin 0.0507 0.3732 0.6881
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0258 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Loa Loa (eye worm) hypothetical protein 0.0171 0.1207 0.1207
Echinococcus multilocularis GPCR, family 2 0.0032 0.0159 0.0252
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0021 0.0077 0.1285
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0058 0.0048
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium tuberculosis Probable transcriptional regulatory protein KdpE 0.0031 0.0151 0.097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0019 0.0168
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0063 0.0396 0.0738
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0097 0.213
Brugia malayi nuclear receptor NHR-88 0.0033 0.0168 0.0168
Loa Loa (eye worm) abnormal epIthelia family member 0.0025 0.0109 0.0109
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0061 0.0061
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.021 0.1037
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0007 0.0012
Brugia malayi photoreceptor-specific nuclear receptor 0.0078 0.0507 0.0507
Schistosoma mansoni rab6-interacting 0.0021 0.0075 0.0139
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0024 0.0097 0.0476
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0.0001 0.0014
Brugia malayi laminin alpha chain 0.0025 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0024 0.0097 0.1505
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0387 0.6511
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0097 0.0476
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Leishmania major ribonuclease H1, putative 0.0022 0.0081 0.0396
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.008 0.0519 0.0957
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.2931
Toxoplasma gondii ribonuclease HI protein 0.0022 0.0081 0.0305
Echinococcus multilocularis cpg binding protein 0.0031 0.0152 0.0241
Leishmania major short chain dehydrogenase-like protein 0.0024 0.0097 0.0476
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0058 0.0957
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0147 0.1026 0.3864
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0356 0.593
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0058 0.0957
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0147 0.1026 0.1912
Echinococcus multilocularis dna polymerase eta 0.0035 0.0183 0.0289
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.021 0.1037
Brugia malayi hypothetical protein 0.0035 0.0181 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0078 0.0507 0.0507
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0024 0.0097 0.0476
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0061 0.0897
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0019 0.1248
Brugia malayi hypothetical protein 0.0171 0.1207 0.1207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0366
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0168 0.031
Leishmania major hypothetical protein, conserved 0.0026 0.0114 0.056
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0021 0.0077 0.0144
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0132 0.0132
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0061 0.0061
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0061 0.0113
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Echinococcus multilocularis Ankyrin 0.0015 0.0033 0.0053
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0097 0.0179
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Mycobacterium ulcerans adenylylate/guanylate cyclase 0.0031 0.0151 0.2526
Schistosoma mansoni phosphoglucomutase 0.0022 0.0081 0.0151
Onchocerca volvulus 0.0029 0.014 0.0843
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0024 0.0097 0.0366
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0168 0.031
Loa Loa (eye worm) hypothetical protein 0.0069 0.0437 0.0437
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0024 0.0097 0.0439
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0032
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Echinococcus multilocularis conserved hypothetical protein 0.0724 0.5365 0.8491
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0021 0.0077 0.0751
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0183 0.0289
Echinococcus granulosus ecdysone induced protein 78C 0.0078 0.0507 0.0935
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.0097 0.0586
Brugia malayi polk-prov protein 0.0038 0.0205 0.0205
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.021 0.3446
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0139 0.0839
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0058 0.0048
Toxoplasma gondii microneme protein MIC17A 0.0023 0.0095 0.0358
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0033 0.0033
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0061 0.0061
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0114 0.056
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Echinococcus granulosus Ankyrin 0.0015 0.0033 0.0062
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0024 0.0097 0.0476
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0168 0.031
Onchocerca volvulus 0.0029 0.0139 0.0839
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.018 0.1545
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Trichomonas vaginalis sensor histidine kinase, putative 0.0031 0.0151 0.2421
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0139 0.0839
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0183 0.034
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0058 0.0048
Onchocerca volvulus Sepiapterin reductase homolog 0.0024 0.0097 0.0586
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0067 0.0422 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0061 0.0897
Brugia malayi RNase H family protein 0.0022 0.0081 0.0081
Trypanosoma brucei unspecified product 0.0023 0.0095 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Wolbachia endosymbiont of Brugia malayi response regulator 0.0031 0.0151 0.5512
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0021 0.0077 0.1285
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0127 0.0622
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0109 0.0172
Brugia malayi hypothetical protein 0.0021 0.0075 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Brugia malayi hypothetical protein 0.0045 0.0258 0.0258
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0114 0.056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0058 0.0957
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0078 0.0507 0.0507
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0058 0.0048
Onchocerca volvulus 0.0024 0.0097 0.0586
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0024 0.0097 0.0179
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0356 0.593
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0075 0.1257
Loa Loa (eye worm) translation initiation factor 4E 0.0067 0.0422 0.0422
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0031 0.0151 0.2421
Toxoplasma gondii microneme protein MIC17B 0.0023 0.0095 0.0358
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0437 0.0437
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0024 0.0097 0.1505
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0031 0.0151 0.5512
Loa Loa (eye worm) cytochrome P450 0.0018 0.0058 0.0058
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0097 0.1622
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0097 0.0179
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Leishmania major hypothetical protein, conserved 0.0058 0.0356 0.1755
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.127
Echinococcus granulosus pikachurin 0.0025 0.0109 0.0201
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0032 0.0196
Loa Loa (eye worm) hypothetical protein 0.0045 0.0258 0.0258
Onchocerca volvulus 0.0028 0.0132 0.0796
Schistosoma mansoni thyroid hormone receptor 0.0078 0.0507 0.0945
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0183 0.0898
Brugia malayi PAS domain containing protein 0.0051 0.0303 0.0303
Mycobacterium leprae TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN PRRA 0.0031 0.0151 0.1264
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0097 0.0181
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Mycobacterium leprae conserved hypothetical protein 0.0152 0.1062 1
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0024 0.0097 0.0439
Onchocerca volvulus 0.0024 0.0097 0.0586
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0058 0.0957
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.0097 0.0154
Toxoplasma gondii subtilisin SUB12 0.0023 0.0095 0.0358
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0095 0.0095
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0168 0.0313
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0058 0.0356 0.0356
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0159 0.0252
Loa Loa (eye worm) hypothetical protein 0.0028 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.021 0.4876
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0097 0.1622
Mycobacterium ulcerans two-component system transcriptional regulator 0.0031 0.0151 0.2526
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Schistosoma mansoni retinal dehydrogenase 0.0024 0.0097 0.0181
Giardia lamblia Hypothetical protein 0.0018 0.0053 0.0875
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0147 0.1026 0.1891
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0024 0.0097 0.0154
Loa Loa (eye worm) steroid hormone receptor 0.0078 0.0507 0.0507
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0147 0.1026 0.1623
Onchocerca volvulus 0.0024 0.0097 0.0586
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0021 0.0077 0.0558
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0097 0.0179
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0019 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0127 0.0127
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Mycobacterium ulcerans two component system response phosphate regulon transcriptional regulator, PhoP 0.0031 0.0151 0.2526
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0024 0.0097 0.0439
Schistosoma mansoni hypothetical protein 0.0032 0.0159 0.0296
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Giardia lamblia DINP protein human, muc B family 0.0042 0.0233 0.392
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0058 0.0957
Schistosoma mansoni netrin receptor unc5 0.0015 0.0032 0.0061
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0097 0.0476
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0356 0.0563
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0258 0.0258
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0021 0.0077 0.0241
Entamoeba histolytica short chain dehydrogenase family protein 0.0024 0.0097 0.213
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0168 0.0266
Loa Loa (eye worm) hypothetical protein 0.0457 0.3358 0.3358
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.075
Brugia malayi conserved hypotetical protein 0.0033 0.0168 0.0168
Mycobacterium tuberculosis Conserved protein 0.0021 0.0077 0.0241
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.021 0.0388
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0021 0.0077 0.1163
Treponema pallidum chemotaxis response regulator (cheY) 0.0031 0.0151 0.2306
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0067 0.0422 0.2083
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0168 0.0168
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0115
Onchocerca volvulus 0.0023 0.0095 0.0574
Brugia malayi Dehydrogenases, short chain protein 2 0.0024 0.0097 0.0097
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0387 0.0722
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0039 0.0209 0.2035
Giardia lamblia hypothetical protein 0.0058 0.0356 0.5986
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0261
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0097 0.1622
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0075 0.0138
Entamoeba histolytica hypothetical protein 0.0035 0.0181 0.4171
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0053 0.0875
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0168 0.0168
Echinococcus granulosus lamin 0.0028 0.0132 0.0243
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0387 0.1909
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0356 0.593
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.009 0.0594 0.2931
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0019 0.0168
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0058 0.0957
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0024 0.0097 0.1505
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0203 0.0203
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0356 0.1341
Loa Loa (eye worm) PAN domain-containing protein 0.0023 0.0095 0.0095
Loa Loa (eye worm) PDE1B protein 0.0147 0.1026 0.1026
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0097 0.1634
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0058 0.0058
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0058 0.0356 0.0656
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0356 0.0663
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0115
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0058 0.0356 0.0663
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0021 0.0077 0.0144
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0168 0.0313
Toxoplasma gondii oxidoreductase, putative 0.0024 0.0097 0.0366
Schistosoma mansoni retinoic acid receptor RXR 0.0078 0.0507 0.0945
Loa Loa (eye worm) hypothetical protein 0.0029 0.0139 0.0139
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0168 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0078 0.0507 0.0507
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 0.1107
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0019 0.0089
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0147 0.1026 0.5065
Giardia lamblia Guanine phosphoribosyltransferase 0.009 0.0594 1
Toxoplasma gondii PAN domain-containing protein 0.0364 0.2654 1
Echinococcus multilocularis serotonin transporter 0.0063 0.0396 0.0627
Loa Loa (eye worm) dehydrogenase 0.0024 0.0097 0.0097
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0097 0.0439
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.0507 0.0803
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.3062 0.4847
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0039 0.0209 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0078 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0109
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0356 0.593
Brugia malayi Doublecortin family protein 0.0021 0.0075 0.0075
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0078 0.0507 0.0945
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0024 0.0097 0.1499
Onchocerca volvulus 0.0024 0.0097 0.0586
Schistosoma mansoni hypothetical protein 0.0032 0.0159 0.0296
Schistosoma mansoni follistatin 0.002 0.0069 0.0129
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0061 0.0097
Plasmodium falciparum phosphodiesterase delta, putative 0.0058 0.0356 0.5992
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0019 0.0089
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0031 0.0151 0.2421
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0387 0.6511
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0021 0.0077 0.0377
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0078 0.0507 0.0507
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0078 0.0507 0.0507
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0001 0.0002
Brugia malayi dehydrogenases, short chain protein 9 0.0024 0.0097 0.0097
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0233 0.1789
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0147 0.1026 0.5065
Schistosoma mansoni phosphoglucomutase 0.0022 0.0081 0.0151
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Brugia malayi nuclear receptor RXR 0.0033 0.0168 0.0168
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0067 0.0422 0.0668
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0058 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0356 0.1755
Schistosoma mansoni hypothetical protein 0.0418 0.3062 0.5709
Leishmania major cytochrome p450-like protein 0.0018 0.0058 0.028
Loa Loa (eye worm) oxidoreductase 0.0024 0.0097 0.0097
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0032 0.0051
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0024 0.0097 0.0097
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.0439
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Brugia malayi Cytochrome P450 family protein 0.0018 0.0058 0.0058
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0097 0.213
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0097 0.0181
Leishmania major DNA polymerase kappa, putative 0.0042 0.0233 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0053 0.0748
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0058 0.0957
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0024 0.0097 0.075
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0356 0.0656
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0061 0.0115
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0024 0.0097 0.213
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.009 0.0594 0.1107
Brugia malayi laminin-like protein K08C7.3 precursor 0.0025 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0033 0.0168 0.0168
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0097 0.1622
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0069 0.0436 0.3797
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.0097 0.0179
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0058 0.0356 0.1755
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0168 0.031
Brugia malayi PAN domain containing protein 0.0023 0.0095 0.0095
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0097 0.1622
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0097 0.0097
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0356 0.1755

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 52 nM Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells ChEMBL. 18294847
Ki (binding) = 52 nM Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells ChEMBL. 18294847

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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