Detailed information for compound 947757

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 352.412 | Formula: C14H20N6O3S
  • H donors: 2 H acceptors: 5 LogP: -0.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N(c1cnc2c(n1)cc[nH]2)C)N[C@H]1CCCN(C1)S(=O)(=O)C
  • InChi: 1S/C14H20N6O3S/c1-19(12-8-16-13-11(18-12)5-6-15-13)14(21)17-10-4-3-7-20(9-10)24(2,22)23/h5-6,8,10H,3-4,7,9H2,1-2H3,(H,15,16)(H,17,21)/t10-/m0/s1
  • InChiKey: GJAHMBFLWRYELA-JTQLQIEISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens Janus kinase 3 Starlite/ChEMBL References
Homo sapiens Janus kinase 1 Starlite/ChEMBL References
Homo sapiens Janus kinase 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0019 0.0046 0.0051
Plasmodium falciparum DNA repair protein REV1, putative 0.0017 0.0037 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0256 0.109 0.1221
Leishmania major beta tubulin 0.2035 0.8921 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0488 0.0488
Schistosoma mansoni ap endonuclease 0.0021 0.0057 0.0064
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0107 0.0119
Loa Loa (eye worm) hypothetical protein 0.0042 0.015 0.015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0107 0.0119
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0208 0.0232
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.2899 0.325
Echinococcus granulosus tubulin beta 4A class IVa 0.2035 0.8921 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0053 0.0199 0.0873
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0082 0.0091
Leishmania major cathepsin L-like protease 0.0138 0.0573 0.0641
Brugia malayi tubulin alpha-2 chain 0.1534 0.6715 0.6715
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0028 0.0028
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0024 0.007 0.0304
Echinococcus granulosus adenine phosphoribosyltransferase 0.0024 0.007 0.0078
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.001 0.0009 0.0009
Loa Loa (eye worm) tubulin alpha-3 chain 0.0914 0.3987 0.3987
Trypanosoma brucei epsilon tubulin 0.1249 0.5464 0.6125
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0082 0.0091
Echinococcus multilocularis Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Brugia malayi Protein kinase domain containing protein 0.0013 0.0021 0.0021
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0072
Loa Loa (eye worm) nuclear hormone receptor 0.0063 0.024 0.024
Giardia lamblia Gamma tubulin 0.1251 0.5471 0.6132
Loa Loa (eye worm) tubulin alpha chain 0.1534 0.6715 0.6715
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Brugia malayi CXXC zinc finger family protein 0.0028 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0045 0.0194
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0124 0.0138
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0078 0.0086
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0133 0.055 0.0616
Schistosoma mansoni ap endonuclease 0.0021 0.0057 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.043 0.043
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0213 0.0238
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0024 0.007 0.0078
Leishmania major beta tubulin 0.2035 0.8921 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Echinococcus multilocularis tubulin alpha 3 chain 0.1534 0.6715 0.7528
Trypanosoma brucei beta tubulin 0.1145 0.5003 0.5608
Echinococcus granulosus tubulin alpha chain 0.1534 0.6715 0.7528
Brugia malayi Adenine phosphoribosyltransferase 0.0024 0.007 0.007
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0013 0.0021 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0046 0.0051
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0525 0.2274 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0013 0.0021 0.0023
Entamoeba histolytica hypothetical protein 0.0219 0.0927 0.1038
Brugia malayi Pre-SET motif family protein 0.0029 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0013 0.0014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus granulosus tubulin epsilon chain 0.1249 0.5464 0.6125
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0103 0.0416 0.0466
Echinococcus granulosus tubulin gamma 1 chain 0.1251 0.5471 0.6133
Echinococcus granulosus thyroid hormone receptor alpha 0.0063 0.024 0.0269
Schistosoma mansoni nuclear hormone receptor 0.0133 0.055 0.0616
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0063 0.007
Brugia malayi steroid hormone receptor 0.0133 0.055 0.055
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.0544 0.0608
Brugia malayi Cytochrome P450 family protein 0.0046 0.0165 0.0165
Echinococcus granulosus tumor protein p63 0.0379 0.1632 0.1829
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0013 0.0014
Echinococcus granulosus Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Echinococcus granulosus geminin 0.0359 0.1545 0.1732
Trypanosoma brucei trypanothione reductase 0.0053 0.0197 0.022
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.0149
Leishmania major xanthine phosphoribosyltransferase 0.0103 0.0416 0.0466
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Trichomonas vaginalis heat shock protein, putative 0.002 0.0052 0.0058
Trichomonas vaginalis tubulin alpha chain, putative 0.062 0.2693 0.3018
Echinococcus multilocularis Protein lozenge 0.0286 0.1223 0.1371
Loa Loa (eye worm) dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0103 0.0416 0.0416
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0057 0.0064
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.0274 0.0307
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0022
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0008 0.0001 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0102 0.0114
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.007 0.0274 0.0274
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0013 0.0021 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0213 0.0238
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0133 0.055 0.0616
Trichomonas vaginalis tubulin epsilon chain, putative 0.2035 0.8921 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0044 0.0191
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0013 0.0022 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0133 0.055 0.055
Echinococcus granulosus caspase 0.0027 0.0082 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0281
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0312 0.0349
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Plasmodium falciparum tubulin gamma chain 0.1251 0.5471 0.6132
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0124 0.0138
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1009 0.4405 0.4938
Echinococcus multilocularis beta tubulin 0.2035 0.8921 1
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Echinococcus granulosus Tubulin beta 2C chain 0.2035 0.8921 1
Echinococcus granulosus c src tyrosine kinase 0.0013 0.0021 0.0023
Trichomonas vaginalis tubulin gamma chain, putative 0.1249 0.5464 0.6125
Leishmania major beta tubulin 0.2035 0.8921 1
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0057 0.0063
Onchocerca volvulus 0.0013 0.0021 0.002
Giardia lamblia Grp94/Hsp90 0.0026 0.0078 0.0086
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0044 0.0191
Echinococcus granulosus dnaJ subfamily B 0.0395 0.1704 0.191
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0024 0.007 0.0304
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0065 0.0281
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0046 0.0046
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0069 0.0069
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0102 0.0102
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0133 0.055 0.0616
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus multilocularis hypothetical protein 0.1534 0.6715 0.7528
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0044 0.0191
Schistosoma mansoni hypothetical protein 0.0047 0.0169 0.019
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0045 0.005
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0208 0.0233
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0165 0.0184
Loa Loa (eye worm) hypothetical protein 0.0085 0.034 0.034
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Loa Loa (eye worm) fibroinase 0.0036 0.0124 0.0124
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.0113
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0045 0.0049
Leishmania major DNA polymerase kappa, putative 0.006 0.0227 0.0254
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0133 0.055 0.055
Brugia malayi hypothetical protein 0.0228 0.097 0.097
Plasmodium vivax vivapain-2 0.0036 0.0124 0.0138
Loa Loa (eye worm) steroid hormone receptor 0.0133 0.055 0.055
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0013
Giardia lamblia Fructose-bisphosphate aldolase 0.0578 0.2508 0.2811
Schistosoma mansoni intermediate filament proteins 0.0027 0.0084 0.0094
Trichomonas vaginalis lymphoid specific helicase, putative 0.0012 0.0017 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Schistosoma mansoni tubulin subunit gamma 0.1251 0.5471 0.6133
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0082
Onchocerca volvulus 0.0027 0.0084 0.0083
Brugia malayi hypothetical protein 0.0063 0.024 0.024
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0065
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0312 0.137
Leishmania major hypothetical protein, conserved 0.0057 0.0213 0.0238
Schistosoma mansoni alpha tubulin 0.1534 0.6715 0.7528
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus tubulin alpha 1C chain 0.1534 0.6715 0.7528
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0044 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0133 0.055 0.055
Mycobacterium tuberculosis Probable monooxygenase 0.001 0.0006 0.0022
Leishmania major heat shock protein, putative 0.0013 0.0022 0.0024
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.043 0.0481
Trypanosoma brucei DNA polymerase eta, putative 0.0053 0.0199 0.0222
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.0001 0.0001
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0014 0.0015
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0069 0.0076
Toxoplasma gondii thioredoxin reductase 0.0053 0.0197 0.022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.029 0.0325
Echinococcus granulosus tubulin delta chain 0.0525 0.2274 0.255
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0001 0.0001
Plasmodium vivax heat shock protein, putative 0.0013 0.0022 0.0024
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0184 0.0773 0.0867
Schistosoma mansoni inositol monophosphatase 0.0039 0.0134 0.015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0079 0.0089
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0065 0.0281
Loa Loa (eye worm) tubulin beta-2A chain 0.2035 0.8921 0.8921
Plasmodium falciparum glutathione reductase 0.0018 0.0045 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.015 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0057 0.0063
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.0001 0.0001
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0152 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Echinococcus multilocularis lamin dm0 0.0027 0.0084 0.0094
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0146 0.0146
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0106 0.0119
Onchocerca volvulus Globin homolog 0.001 0.0006 0.0005
Echinococcus multilocularis oxidoreductase 0.0008 0.0001 0.0001
Leishmania major DNA damage repair protein, putative 0.0017 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.029 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0046 0.0052
Brugia malayi nuclear hormone receptor 0.0063 0.024 0.024
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0107 0.0119
Leishmania major beta tubulin 0.2035 0.8921 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0274 0.0274
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0063 0.024 0.0269
Plasmodium falciparum tubulin delta chain, putative 0.0525 0.2274 0.2549
Echinococcus multilocularis tubulin alpha chain 0.1534 0.6715 0.7528
Brugia malayi ImpB/MucB/SamB family protein 0.0053 0.0199 0.0199
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Brugia malayi orphan nuclear receptor NR2E1 0.0063 0.024 0.024
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Echinococcus granulosus cpg binding protein 0.0029 0.0093 0.0104
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0013 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0085 0.0085
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0045 0.0049
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0022 0.0024
Trypanosoma brucei heat shock protein 84, putative 0.0013 0.0022 0.0024
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0165 0.0722
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Leishmania major beta tubulin 0.2035 0.8921 1
Onchocerca volvulus 0.0047 0.0169 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.0071
Brugia malayi hypothetical protein 0.0043 0.0152 0.0152
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Schistosoma mansoni hypothetical protein 0.0219 0.0927 0.1039
Loa Loa (eye worm) tubulin beta chain 0.2035 0.8921 0.8921
Loa Loa (eye worm) nuclear receptor NHR-67 0.0063 0.024 0.024
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0129 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Giardia lamblia Alpha-tubulin 0.1534 0.6715 0.7527
Trypanosoma brucei chrX additional, unordered contigs 0.0017 0.0037 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0152 0.0171
Brugia malayi beta-tubulin, identical 0.2035 0.8921 0.8921
Echinococcus granulosus lamin dm0 0.0027 0.0084 0.0094
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0097 0.0392 0.0439
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0133 0.055 0.0616
Treponema pallidum hypothetical protein 0.0024 0.007 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Treponema pallidum adenine phosphoribosyltransferase 0.0024 0.007 0.023
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus multilocularis geminin 0.0359 0.1545 0.1732
Echinococcus multilocularis cysteine protease 0.0036 0.0124 0.0139
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0184 0.0773 0.0866
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0172
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0282 0.1207 0.5304
Giardia lamblia DNA repair protein RAD52 0.0342 0.1468 0.1645
Leishmania major cathepsin L-like protease 0.0036 0.0124 0.0138
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0106 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Loa Loa (eye worm) hypothetical protein 0.0036 0.0124 0.0124
Brugia malayi RNA, U transporter 1 0.0092 0.0369 0.0369
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0044 0.0191
Brugia malayi SRC-1 0.0013 0.0021 0.0021
Trypanosoma brucei zeta tubulin, putative 0.1622 0.7105 0.7964
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0261 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0082 0.0092
Trypanosoma brucei unspecified product 0.0037 0.0126 0.0141
Leishmania major beta tubulin 0.2035 0.8921 1
Schistosoma mansoni kinase 0.0054 0.0201 0.0225
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0256 0.109 0.1221
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0107 0.0107
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0045 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0152 0.0171
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Schistosoma mansoni uracil phosphoribosyltransferase 0.0024 0.007 0.0078
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.007 0.0274 0.0307
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni tubulin subunit delta 0.0525 0.2274 0.255
Echinococcus granulosus nuclear receptor nhr 48 0.0063 0.024 0.0269
Loa Loa (eye worm) hypothetical protein 0.007 0.0274 0.0274
Leishmania major beta tubulin 0.2035 0.8921 1
Trypanosoma brucei tubulin delta chain 0.1181 0.5164 0.5788
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Plasmodium vivax unspecified product 0.0012 0.0017 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0281
Loa Loa (eye worm) tubulin alpha-2 chain 0.1534 0.6715 0.6715
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0084 0.0084
Echinococcus granulosus importin subunit beta 1 0.0032 0.0106 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0013 0.0021 0.0021
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0124 0.0139
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0213 0.0239
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Brugia malayi hypothetical protein 0.0013 0.0021 0.0021
Echinococcus multilocularis endoplasmin 0.0026 0.0078 0.0087
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Brugia malayi Doublecortin family protein 0.0043 0.0152 0.0152
Schistosoma mansoni nuclear hormone receptor 0.0063 0.024 0.0269
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi Cytochrome P450 family protein 0.0046 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0031 0.0102 0.0102
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0134 0.015
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0153 0.0171
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0124 0.0138
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0013 0.0014
Loa Loa (eye worm) TK protein kinase 0.0013 0.0021 0.0021
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Plasmodium falciparum thioredoxin reductase 0.0053 0.0197 0.022
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0124 0.0139
Giardia lamblia Beta tubulin 0.2035 0.8921 1
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Schistosoma mansoni thyroid hormone receptor 0.0274 0.1171 0.1313
Onchocerca volvulus Bile acid receptor homolog 0.0133 0.055 0.0549
Schistosoma mansoni rotamase 0.0037 0.0129 0.0144
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0065 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0544 0.0609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0014 0.0014
Toxoplasma gondii peptidylprolyl isomerase 0.0037 0.0125 0.0139
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0057 0.0057
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0134 0.0556 0.2441
Onchocerca volvulus 0.0036 0.0124 0.0123
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.0149
Echinococcus multilocularis tubulin delta chain 0.0525 0.2274 0.255
Trypanosoma cruzi beta tubulin, putative 0.2035 0.8921 1
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.097 0.1087
Trichomonas vaginalis tubulin alpha chain, putative 0.1145 0.5003 0.5608
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0069 0.0076
Brugia malayi Nuclear hormone receptor-like 1 0.0133 0.055 0.055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0057 0.0063
Echinococcus multilocularis musashi 0.0027 0.0084 0.0094
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0024 0.007 0.0078
Brugia malayi hypothetical protein 0.0011 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase Blk 0.0013 0.0021 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0035 0.0151
Echinococcus granulosus peroxisome assembly protein 26 0.1534 0.6715 0.7528
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.029 0.029
Echinococcus granulosus tubulin alpha chain 0.1534 0.6715 0.7528
Echinococcus granulosus endoplasmin 0.0026 0.0078 0.0087
Brugia malayi hypothetical protein 0.0032 0.0106 0.0106
Plasmodium falciparum cysteine proteinase falcipain 1 0.0019 0.0046 0.0051
Echinococcus granulosus GPCR family 2 0.0031 0.0102 0.0114
Trichomonas vaginalis tubulin epsilon chain, putative 0.2035 0.8921 1
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0284 0.0318
Plasmodium falciparum orotate phosphoribosyltransferase 0.0024 0.007 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus multilocularis caspase 8 0.0027 0.0082 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0078 0.0086
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0184 0.0773 0.0867
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0044 0.0191
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0107 0.0119
Echinococcus granulosus tyrosine protein kinase shark 0.0013 0.0021 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.0852 0.0852
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0129 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Loa Loa (eye worm) hypothetical protein 0.0043 0.0152 0.0152
Trichomonas vaginalis rotamase, putative 0.0037 0.0125 0.014
Echinococcus granulosus expressed protein 0.0037 0.0129 0.0144
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0027 0.0082 0.0092
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0107 0.0119
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0078 0.0087
Loa Loa (eye worm) tubulin alpha 2 0.0389 0.1676 0.1676
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.024 0.0269
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0046 0.0051
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0914 0.3987 0.4469
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0525 0.2274 0.255
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0184 0.0206
Echinococcus multilocularis tubulin alpha 0.1145 0.5003 0.5608
Schistosoma mansoni heat shock protein 0.0013 0.0022 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0133 0.055 0.055
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0044 0.0191
Loa Loa (eye worm) hypothetical protein 0.228 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0094 0.0105
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0113
Treponema pallidum fructose-bisphosphate aldolase 0.0578 0.2508 1
Plasmodium vivax tubulin alpha chain, putative 0.1534 0.6715 0.7527
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0063 0.024 0.024
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0057 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0573 0.0641
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0127 0.0524 0.23
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi cathepsin L-like precursor 0.0024 0.0071 0.0071
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0013 0.0021 0.0023
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0039 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trypanosoma cruzi cysteine protease, putative 0.0019 0.0046 0.0051
Brugia malayi tubulin alpha chain - mouse 0.1534 0.6715 0.6715
Schistosoma mansoni caspase-3 (C14 family) 0.0027 0.0082 0.0092
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0046 0.0052
Brugia malayi DKFZp564C0469 protein 0.0011 0.0013 0.0013
Trypanosoma cruzi heat shock protein, putative 0.0013 0.0022 0.0024
Leishmania major beta tubulin 0.2035 0.8921 1
Echinococcus multilocularis tubulin alpha chain 0.1534 0.6715 0.7528
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Echinococcus multilocularis Chromo domain 0.0011 0.0014 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0044 0.0191
Brugia malayi small heat shock protein 0.0648 0.2815 0.2815
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Schistosoma mansoni lozenge 0.0286 0.1223 0.1371
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0184 0.0773 0.0867
Brugia malayi Tubulin alpha-2 chain 0.1534 0.6715 0.6715
Trypanosoma cruzi metacaspase, putative 0.0027 0.0082 0.0091
Schistosoma mansoni endoplasmin 0.0032 0.0107 0.012
Loa Loa (eye worm) helicase DNA-binding protein 0.0011 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0013 0.0021 0.0021
Brugia malayi protein-tyrosine kinase 0.0013 0.0021 0.0021
Plasmodium falciparum importin beta, putative 0.0032 0.0106 0.0118
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0057 0.0064
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0013 0.0021 0.0022
Echinococcus multilocularis heat shock protein 90 0.0032 0.0107 0.012
Schistosoma mansoni hypothetical protein 0.0141 0.0585 0.0656
Brugia malayi hypothetical protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0024 0.007 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0133 0.055 0.055
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0133 0.055 0.055
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0069 0.0077
Toxoplasma gondii beta-tubulin, putative 0.2035 0.8921 1
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Brugia malayi intermediate filament protein 0.0027 0.0084 0.0084
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0046 0.0051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0134 0.015
Echinococcus multilocularis tar DNA binding protein 0.0134 0.0555 0.0622
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0107 0.0119
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0046 0.0051
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0023 0.0023
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0022 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.024 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0165 0.0165
Brugia malayi Cathepsin L-like precursor 0.0012 0.0017 0.0017
Leishmania major cathepsin L-like protease 0.0138 0.0573 0.0641
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0017
Echinococcus multilocularis heat shock protein 90 0.0026 0.0078 0.0087
Entamoeba histolytica deoxycytidyl transferase, putative 0.0053 0.0199 0.0222
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0078 0.0338
Schistosoma mansoni lipoxygenase 0.0256 0.109 0.1221
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0044 0.0191
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0094 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0124 0.0138
Loa Loa (eye worm) tubulin gamma chain 0.1251 0.5471 0.5471
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Trypanosoma brucei beta tubulin 0.2035 0.8921 1
Loa Loa (eye worm) histone methyltransferase 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0017
Plasmodium vivax tubulin gamma chain, putative 0.1251 0.5471 0.6132
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0069 0.0076
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0013 0.0014
Trypanosoma brucei metacaspase MCA3 0.0027 0.0082 0.0091
Loa Loa (eye worm) hypothetical protein 0.228 1 1
Trichomonas vaginalis rotamase, putative 0.0037 0.0129 0.0144
Echinococcus multilocularis Tubulin beta 2C chain 0.2035 0.8921 1
Brugia malayi Inositol-1 0.0039 0.0134 0.0134
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0102 0.0444
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0028 0.0028
Brugia malayi Cytochrome P450 family protein 0.0018 0.0044 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0573 0.0641
Echinococcus multilocularis tubulin alpha chain 0.1534 0.6715 0.7528
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0134 0.0586
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0102 0.0114
Echinococcus granulosus FTZ F1 alpha 0.0133 0.055 0.0616
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0065 0.0281
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Schistosoma mansoni rab6-interacting 0.0043 0.0152 0.0171
Trypanosoma brucei beta tubulin 0.2035 0.8921 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0012 0.0017 0.0017
Leishmania major zeta tubulin, putative 0.1622 0.7105 0.7964
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0199 0.0199
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.0001 0.0001
Trypanosoma brucei beta tubulin 0.2035 0.8921 1
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Onchocerca volvulus 0.0036 0.0124 0.0123
Schistosoma mansoni lamin 0.0027 0.0084 0.0094
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0133 0.055 0.0616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Onchocerca volvulus 0.0055 0.0208 0.0207
Echinococcus granulosus oxidoreductase 0.0008 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0555 0.0622
Schistosoma mansoni cpg binding protein 0.0029 0.0093 0.0104
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.0544 0.0609
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Entamoeba histolytica tubulin gamma chain 0.1251 0.5471 0.6132
Onchocerca volvulus Protein ultraspiracle homolog 0.0133 0.055 0.0549
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.1484 0.1484
Brugia malayi hypothetical protein 0.001 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0097 0.0392 0.0439
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0082 0.0091
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0065 0.0281
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0163 0.0182
Trypanosoma brucei alpha tubulin 0.1534 0.6715 0.7527
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0197 0.022
Schistosoma mansoni retinoic acid receptor RXR 0.0133 0.055 0.0616
Brugia malayi Cell death protein 3 precursor 0.0027 0.0082 0.0082
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0024 0.007 0.0304
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Onchocerca volvulus 0.0036 0.0124 0.0123
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0134 0.0149
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0024 0.007 0.0304
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0044 0.0191
Echinococcus multilocularis cpg binding protein 0.0029 0.0093 0.0104
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0057 0.0177
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0045 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0342 0.1468 0.1645
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0124 0.0124
Echinococcus multilocularis BRK domain 0.0011 0.0014 0.0016
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0037 0.0041
Entamoeba histolytica hypothetical protein 0.0011 0.0013 0.0013
Brugia malayi tailless protein 0.0063 0.024 0.024
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0035 0.0151
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0037 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0044 0.0191
Trichomonas vaginalis tubulin epsilon chain, putative 0.0525 0.2274 0.255
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.001 0.0006 0.0006
Loa Loa (eye worm) globin family protein 0.001 0.0006 0.0006
Brugia malayi nuclear hormone receptor family member nhr-6 0.0063 0.024 0.024
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0011 0.0013 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0133 0.055 0.055
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0094 0.0105
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0057 0.0246
Schistosoma mansoni ran 0.0024 0.0069 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0071 0.008
Loa Loa (eye worm) cytochrome P450 0.0018 0.0044 0.0044
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.0544 0.0608
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0184 0.0206
Leishmania major adenylate cyclase-like protein 0.001 0.0006 0.0006
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0125 0.0139
Echinococcus multilocularis cysteine protease 0.0036 0.0124 0.0139
Schistosoma mansoni DNA ligase IV 0.0011 0.0013 0.0014
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0027 0.0082 0.0092
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.0544 0.2387
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0082 0.0091
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0071 0.0071
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.024 0.0269
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0039 0.8282
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Brugia malayi hypothetical protein 0.0069 0.0268 0.0268
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.043 0.0482
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Echinococcus granulosus snurportin 1 0.0345 0.1484 0.1663
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0045 0.0194
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0065
Trypanosoma brucei epsilon tubulin 0.1145 0.5003 0.5608
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0044 0.0191
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.0184
Trichomonas vaginalis tubulin alpha chain, putative 0.062 0.2693 0.3018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0035 0.0151
Loa Loa (eye worm) BRM protein 0.0034 0.0114 0.0114
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0282 0.1207 0.5304
Brugia malayi hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni tubulin subunit alpha 0.1534 0.6715 0.7528
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0044 0.005
Brugia malayi hypothetical protein 0.007 0.0274 0.0274
Echinococcus multilocularis tubulin subunit TubB 0.1534 0.6715 0.7528
Schistosoma mansoni nuclear receptor 0.0063 0.024 0.0269
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0102 0.0114
Echinococcus granulosus tyrosine kinase 0.0013 0.0021 0.0023
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0027 0.0082 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Echinococcus granulosus tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Echinococcus granulosus alpha tubulin 0.1534 0.6715 0.7528
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0013 0.0014
Echinococcus multilocularis jun protein 0.0088 0.0351 0.0393
Trypanosoma brucei unspecified product 0.0073 0.0284 0.0318
Brugia malayi photoreceptor-specific nuclear receptor 0.0133 0.055 0.055
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0013 0.0014
Echinococcus granulosus tubulin alpha chain 0.1534 0.6715 0.7528
Trypanosoma brucei tubulin gamma chain 0.1251 0.5471 0.6132
Brugia malayi ecdysteroid receptor 0.0133 0.055 0.055
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0012 0.0017 0.0018
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.0125 0.0139
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0013 0.0022 0.0024
Echinococcus multilocularis beta tubulin 0.2035 0.8921 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.043 0.0429
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.029 0.0325
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.0037 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0102 0.0113
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0044 0.0191
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0045 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0133 0.055 0.0616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi Tubulin alpha chain 0.0525 0.2274 0.2274
Leishmania major beta tubulin 0.2035 0.8921 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0023 0.0023
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.0001 0.0001
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0001 0.0001
Loa Loa (eye worm) tubulin beta chain 0.0525 0.2274 0.2274
Brugia malayi hypothetical protein 0.007 0.0274 0.0274
Plasmodium vivax unspecified product 0.0019 0.0046 0.0051
Loa Loa (eye worm) glutathione reductase 0.0053 0.0197 0.0197
Toxoplasma gondii cathepsin CPL 0.0036 0.0124 0.0138
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0133 0.055 0.0549
Echinococcus multilocularis Tubulin beta 2C chain 0.2035 0.8921 1
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0184 0.0206
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0011 0.0013 0.0052
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Schistosoma mansoni DNA polymerase IV / kappa 0.0017 0.0037 0.0041
Onchocerca volvulus 0.0184 0.0773 0.0773
Loa Loa (eye worm) hypothetical protein 0.0043 0.0152 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0035 0.0151
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0013 0.0013
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0165 0.0184
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0134 0.015
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Trichomonas vaginalis tubulin gamma chain, putative 0.1251 0.5471 0.6133
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0045 0.0049
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0184 0.0206
Leishmania major beta tubulin 0.2035 0.8921 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0102 0.0113
Plasmodium vivax glutathione reductase, putative 0.0053 0.0197 0.022
Loa Loa (eye worm) hypothetical protein 0.0013 0.002 0.002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0133 0.055 0.0616
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0133 0.055 0.0616
Schistosoma mansoni RAR-like nuclear receptor 0.0133 0.055 0.0616
Treponema pallidum heat shock protein 90 0.0026 0.0078 0.0261
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0045 0.0045
Onchocerca volvulus 0.001 0.0006 0.0005
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0013 0.0013
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0069 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0555 0.0622
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0046 0.0046
Onchocerca volvulus 0.0229 0.0974 0.0973
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0133 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0013 0.002 0.002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0065 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0037 0.0041
Echinococcus multilocularis RUN 0.0043 0.0152 0.0171
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.007 0.0304
Brugia malayi SH2 domain containing protein 0.0013 0.0021 0.0021
Trichomonas vaginalis tubulin alpha chain, putative 0.062 0.2693 0.3018
Echinococcus multilocularis tubulin beta 1 chain 0.2035 0.8921 1
Echinococcus multilocularis dna polymerase kappa 0.0079 0.0312 0.035
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0008 0.0001 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0124 0.0139
Echinococcus granulosus RUN 0.0043 0.0152 0.0171
Trichomonas vaginalis set domain proteins, putative 0.0229 0.0974 0.1092
Trypanosoma cruzi metacaspase, putative 0.0027 0.0082 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0525 0.2274 0.255
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.043 0.0481
Schistosoma mansoni alpha tubulin 0.1534 0.6715 0.7528
Brugia malayi TAR-binding protein 0.0134 0.0555 0.0555
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0071 0.0079
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.1534 0.6715 0.6715
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0133 0.055 0.0616
Echinococcus multilocularis tubulin subunit beta 0.2035 0.8921 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0079 0.031 0.1362
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0045 0.0194
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0065 0.0281
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0134 0.0555 0.0555
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Brugia malayi ecdysone receptor 0.0063 0.024 0.024
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0044 0.0191
Schistosoma mansoni endoplasmin 0.0032 0.0107 0.012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.0037 0.0041
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0013 0.0021 0.0023
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0024 0.007 0.0304
Schistosoma mansoni tubulin subunit alpha 0.1534 0.6715 0.7528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0071 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0045 0.0194
Echinococcus multilocularis nibrin 0.0011 0.0013 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0133 0.055 0.055
Trypanosoma brucei metacaspase 0.0027 0.0082 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0133 0.055 0.055
Plasmodium falciparum endoplasmin, putative 0.002 0.0052 0.0057
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0082
Brugia malayi Importin beta-1 subunit 0.0032 0.0106 0.0106
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0013 0.0021 0.0023
Plasmodium vivax tubulin beta chain, putative 0.2035 0.8921 1
Brugia malayi hypothetical protein 0.005 0.0184 0.0184
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0102 0.0114
Trypanosoma cruzi zeta tubulin, putative 0.1622 0.7105 0.7964
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Toxoplasma gondii beta-1 tubulin, putative 0.2035 0.8921 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0044 0.0191
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0094 0.0105
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.006 0.0227 0.0254
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0013 0.0021 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0133 0.055 0.055
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0114
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0065 0.0281
Echinococcus granulosus hypothetical protein 0.0008 0.0001 0.0001
Leishmania major beta tubulin 0.2035 0.8921 1
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0184 0.0206
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0065
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0057 0.0064
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Onchocerca volvulus 0.0036 0.0124 0.0123
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0359 0.1545 0.1732
Echinococcus granulosus tyrosine protein kinase Blk 0.0013 0.0021 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0121 0.0496 0.218
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Plasmodium falciparum tubulin beta chain 0.2035 0.8921 1
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.0001 0.0001
Echinococcus multilocularis tubulin epsilon chain 0.1249 0.5464 0.6125
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0069 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Loa Loa (eye worm) DR-78 0.0063 0.024 0.024
Giardia lamblia Beta tubulin 0.2035 0.8921 1
Plasmodium vivax delta tubulin, putative 0.0525 0.2274 0.2549
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni survival motor neuron protein 0.0047 0.0169 0.019
Onchocerca volvulus 0.062 0.2693 0.2692
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0184 0.0773 0.0867
Onchocerca volvulus 0.0043 0.0152 0.0151
Brugia malayi nuclear receptor RXR 0.007 0.0274 0.0274
Echinococcus multilocularis tubulin alpha chain 0.1534 0.6715 0.7528
Brugia malayi SH2 domain containing protein 0.0013 0.0021 0.0021
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0124 0.0123
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus granulosus tubulin alpha chain 0.1534 0.6715 0.7528
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0013 0.0014
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0045 0.0049
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0152 0.0152
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0024 0.007 0.007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Echinococcus granulosus tubulin alpha 0.1145 0.5003 0.5608
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0184 0.0206
Schistosoma mansoni cpg binding protein 0.0029 0.0093 0.0104
Mycobacterium leprae putative cytochrome p450 0.0018 0.0044 0.0191
Toxoplasma gondii alpha tubulin TUBA1 0.1534 0.6715 0.7527
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0094 0.0105
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0046 0.0052
Onchocerca volvulus 0.0036 0.0124 0.0123
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0228 0.0255
Mycobacterium tuberculosis Probable dehydrogenase 0.0121 0.0496 0.218
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Echinococcus multilocularis GPCR, family 2 0.0031 0.0102 0.0114
Schistosoma mansoni hypothetical protein 0.0013 0.0021 0.0024
Echinococcus granulosus cathepsin l1 0.0036 0.0124 0.0139
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0078 0.0087
Trypanosoma brucei metacaspase MCA2 0.0027 0.0082 0.0091
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0013 0.0021 0.0021
Trichomonas vaginalis tubulin alpha chain, putative 0.2035 0.8921 1
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0312 0.0349
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0124 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0134 0.0556 0.2441
Schistosoma mansoni hypothetical protein 0.0345 0.1484 0.1663
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0024 0.007 0.0304
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0106 0.0118
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0044 0.0191
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0063 0.024 0.024
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0013 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0146 0.0164
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.043 0.043
Echinococcus granulosus cathepsin l1 0.0024 0.0071 0.008
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0011 0.0013 0.0052
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0045 0.0049
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Loa Loa (eye worm) tubulin alpha 2 0.1009 0.4405 0.4405
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Onchocerca volvulus 0.0013 0.0021 0.002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0079 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0274 0.1171 0.1313
Echinococcus granulosus global transcription activator snf2l2 0.0066 0.0255 0.0285
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0072
Schistosoma mansoni tubulin subunit epsilon 0.1249 0.5464 0.6125
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0017 0.0019
Onchocerca volvulus 0.0027 0.0084 0.0083
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0022 0.0022
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0013 0.0022 0.0022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.024 0.0269
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0573 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0107 0.0119
Leishmania major beta tubulin 0.2035 0.8921 1
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0312 0.137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0133 0.055 0.055
Brugia malayi Pre-SET motif family protein 0.0202 0.0852 0.0852
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0146 0.0164
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0134 0.015
Brugia malayi hypothetical protein 0.0008 0.0001 0.0001
Plasmodium falciparum heat shock protein 90 0.0032 0.0107 0.0119
Echinococcus multilocularis tyrosine protein kinase Srms 0.0013 0.0021 0.0023
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0197 0.0197
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0116 0.0508
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0013 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0914 0.3987 0.3987
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.063 0.2736 0.3066
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0008 0.0001 0.0001
Echinococcus multilocularis nuclear receptor nhr 48 0.0063 0.024 0.0269
Brugia malayi follicle stimulating hormone receptor 0.0485 0.2097 0.2097
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0044 0.0191
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0013 0.0021 0.0023
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0133 0.055 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0013 0.0014
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0078 0.0086
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0044 0.0049
Echinococcus granulosus tar DNA binding protein 0.0134 0.0555 0.0622
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0102 0.0114
Brugia malayi nuclear receptor RXR 0.0063 0.024 0.024
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0102 0.0113
Loa Loa (eye worm) hypothetical protein 0.0339 0.1456 0.1456
Plasmodium falciparum alpha tubulin 2 0.1534 0.6715 0.7527
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0053 0.0199 0.0199
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Brugia malayi Globin family protein 0.001 0.0006 0.0006
Echinococcus multilocularis snurportin 1 0.0345 0.1484 0.1663
Trichomonas vaginalis conserved hypothetical protein 0.0525 0.2274 0.255
Brugia malayi bZIP transcription factor family protein 0.0088 0.0351 0.0351
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0044 0.0191
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0124 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Brugia malayi Tubulin alpha-2 chain 0.1534 0.6715 0.6715
Trypanosoma brucei metacaspase 5, putative 0.0027 0.0082 0.0091
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0555 0.0622
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0116 0.0508
Brugia malayi Tubulin beta chain 0.0525 0.2274 0.2274
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Onchocerca volvulus 0.0069 0.0268 0.0267
Loa Loa (eye worm) TAR-binding protein 0.0134 0.0555 0.0555
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0044 0.0191
Plasmodium falciparum DEAD/DEAH box helicase, putative 0.001 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0046 0.0052
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0114
Echinococcus granulosus heat shock protein 90 0.0032 0.0107 0.012
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0107 0.0119
Mycobacterium tuberculosis Probable oxidoreductase 0.0134 0.0556 0.2441
Echinococcus multilocularis tubulin alpha 3 chain 0.1534 0.6715 0.7528
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0044 0.0191
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0124 0.0138
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0008 0.0001 0.0001
Loa Loa (eye worm) alpha-tubulin isotype 2 0.1009 0.4405 0.4405
Giardia lamblia Kinase, PLK 0.0106 0.043 0.0481
Entamoeba histolytica tubulin alpha-1 chain 0.1534 0.6715 0.7527
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0141 0.0585 0.0656
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0044 0.0049
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0017 0.0017
Brugia malayi oxidoreductase 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0339 0.1456 0.1455
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0024 0.007 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0063 0.024 0.024
Entamoeba histolytica hypothetical protein 0.0026 0.0079 0.0088
Trichomonas vaginalis tubulin gamma chain, putative 0.2035 0.8921 1
Trypanosoma cruzi tubulin delta chain 0.1181 0.5164 0.5788
Loa Loa (eye worm) hypothetical protein 0.0228 0.097 0.097
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0057 0.0063
Loa Loa (eye worm) hypothetical protein 0.0055 0.0208 0.0208
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0124 0.0123
Leishmania major beta tubulin 0.2035 0.8921 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0037 0.0125 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0044 0.0191
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0024 0.007 0.023
Echinococcus multilocularis heat shock protein 0.0032 0.0107 0.012
Echinococcus granulosus tubulin alpha chain 0.1534 0.6715 0.7528
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0029 0.0094 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0044 0.0191
Loa Loa (eye worm) hypothetical protein 0.007 0.0274 0.0274
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0024 0.007 0.0077
Trypanosoma brucei alpha tubulin 0.1534 0.6715 0.7527
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0134 0.015
Giardia lamblia Epsilon tubulin 0.063 0.2736 0.3066
Schistosoma mansoni heat shock protein 0.0032 0.0107 0.012
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Onchocerca volvulus 0.0011 0.0013 0.0012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0219 0.0927 0.1039
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0013 0.0021 0.0023
Leishmania major beta tubulin 0.2035 0.8921 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0001 0.0001
Brugia malayi RNA recognition motif domain containing protein 0.0134 0.0555 0.0555
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0153 0.0171
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0184 0.0773 0.0866
Mycobacterium tuberculosis Conserved protein 0.0024 0.007 0.0304
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0184 0.0773 0.0867
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0102 0.0114
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0013 0.0014
Trypanosoma brucei beta tubulin 0.2035 0.8921 1
Schistosoma mansoni transcription factor LCR-F1 0.0219 0.0927 0.1039
Echinococcus multilocularis retinol dehydrogenase 13 0.0008 0.0001 0.0001
Echinococcus granulosus caspase 8 0.0027 0.0082 0.0092
Plasmodium vivax SET domain protein, putative 0.0029 0.0094 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0184 0.0206
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1181 0.5164 0.5788
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus cysteine protease 0.0019 0.0046 0.0052
Loa Loa (eye worm) tubulin alpha 2 0.1009 0.4405 0.4405
Entamoeba histolytica cysteine proteinase 2 0.0019 0.0046 0.0051
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.043 0.0481
Loa Loa (eye worm) hypothetical protein 0.1009 0.4405 0.4405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0065 0.0072
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0467
Schistosoma mansoni topbp1 0.0011 0.0013 0.0014
Loa Loa (eye worm) beta-tubulin 0.2035 0.8921 0.8921
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0044 0.0044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0102 0.0113
Echinococcus granulosus tyrosine protein kinase Src42A 0.0013 0.0021 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0172
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0063 0.024 0.0269
Echinococcus granulosus cathepsin L 0.0019 0.0046 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0044 0.0191
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0046 0.0052
Brugia malayi topoisomerase 0.0011 0.0013 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Mycobacterium ulcerans cell division protein FtsZ 0.0525 0.2274 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0044 0.0191
Loa Loa (eye worm) tubulin beta-4 chain 0.2035 0.8921 0.8921
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0213 0.0238
Toxoplasma gondii orotate phosphoribosyltransferase 0.0024 0.007 0.0077
Leishmania major GTP-binding protein, putative 0.0024 0.0069 0.0076
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0044 0.0191
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0466
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0045 0.0194
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.0071
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0466
Trypanosoma cruzi zeta tubulin, putative 0.1622 0.7105 0.7964
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0133 0.055 0.055
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0165 0.0184
Schistosoma mansoni hypothetical protein 0.0395 0.1704 0.191
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0027 0.0082 0.0092
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0039
Plasmodium vivax DEAD/DEAH helicase, putative 0.001 0.0009 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0114
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0023 0.0065 0.0064
Brugia malayi ImpB/MucB/SamB family protein 0.0053 0.0199 0.0199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Plasmodium vivax tubulin epsilon chain, putative 0.1249 0.5464 0.6125
Onchocerca volvulus 0.228 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0134 0.015
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0057 0.0246
Schistosoma mansoni hypothetical protein 0.0031 0.0102 0.0114
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0024 0.007 0.0304
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0044 0.0191
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0017 0.0019
Brugia malayi Cathepsin L-like precursor 0.0024 0.0071 0.0071
Echinococcus granulosus hypothetical protein 0.0008 0.0001 0.0001
Echinococcus multilocularis c src tyrosine kinase 0.0013 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0399 0.0399
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0107 0.0119
Trichomonas vaginalis ran, putative 0.0024 0.0069 0.0077
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.0001 0.0001
Echinococcus granulosus caspase 2 0.0027 0.0082 0.0092
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.1704 0.191
Leishmania major cytochrome p450-like protein 0.0018 0.0044 0.0049
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0011 0.0014 0.0058
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Loa Loa (eye worm) SRC-1 0.0013 0.0021 0.0021
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0079 0.0089
Echinococcus multilocularis tubulin, beta 4A class IVa 0.2035 0.8921 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0544 0.2387
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0013 0.0021 0.0023
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.0149
Onchocerca volvulus 0.0013 0.0021 0.002
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0013 0.0021 0.0023
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0011 0.0014 0.0016
Toxoplasma gondii beta tubulin 0.2035 0.8921 1
Trypanosoma cruzi tubulin delta chain 0.1181 0.5164 0.5788
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.052 0.0582
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0044 0.0191
Plasmodium falciparum tubulin epsilon chain, putative 0.1249 0.5464 0.6125
Schistosoma mansoni tubulin subunit beta 0.0525 0.2274 0.255
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0008 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0094 0.0105
Loa Loa (eye worm) runx1 0.0286 0.1223 0.1223
Giardia lamblia Replication factor C, subunit 1 0.0011 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0443 0.0495
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0044 0.0049
Leishmania major gamma-tubulin 0.1251 0.5471 0.6132
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.062 0.2693 0.3018
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0044 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0044 0.0191
Echinococcus granulosus tyrosine protein kinase Srms 0.0013 0.0021 0.0023
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0037 0.0041
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.024 0.024
Brugia malayi hypothetical protein 0.001 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0094 0.0094
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0094 0.0105
Brugia malayi Tyrosine-protein kinase abl-1 0.0013 0.0021 0.0021
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0134 0.015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0065 0.0281
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0053 0.0199 0.0223
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0045 0.0049
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0037 0.0041
Leishmania major adenine phosphoribosyltransferase 0.0024 0.007 0.0077
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Loa Loa (eye worm) hypothetical protein 0.007 0.0274 0.0274
Brugia malayi glutathione reductase 0.0053 0.0197 0.0197
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0065 0.0065
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0184 0.0773 0.3398
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0133 0.055 0.055
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.043 0.0482
Plasmodium falciparum glutathione reductase 0.0053 0.0197 0.022
Echinococcus multilocularis tubulin alpha chain 0.1534 0.6715 0.7528
Brugia malayi Globin family protein 0.001 0.0006 0.0006
Brugia malayi hypothetical protein 0.001 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0163 0.0182
Brugia malayi hypothetical protein 0.0339 0.1456 0.1456
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0555 0.0622
Loa Loa (eye worm) alpha-tubulin 0.1534 0.6715 0.6715
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0555 0.0622
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.007 0.0274 0.0307
Echinococcus granulosus steroid dehydrogenase 0.0008 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Brugia malayi nuclear receptor NHR-67 0.0063 0.024 0.024
Giardia lamblia DNA damage repair protein 0.0017 0.0037 0.0041
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0078 0.0086
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0013 0.0013
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0172
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0082 0.0091
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0165 0.0165
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0044 0.0049
Giardia lamblia Alpha-tubulin 0.1534 0.6715 0.7527
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0017
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0213 0.0239
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0024 0.007 0.0304
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Plasmodium vivax endoplasmin, putative 0.0032 0.0107 0.0119
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0086 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0037 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0078 0.0338
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0001 0.0001
Trichomonas vaginalis endoplasmin, putative 0.002 0.0052 0.0058
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0024 0.007 0.0078
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0044 0.0191
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0069 0.0077
Onchocerca volvulus 0.0013 0.0021 0.002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0053 0.0199 0.0223
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0024 0.007 0.0069
Echinococcus multilocularis global transcription activator snf2l2 0.0066 0.0255 0.0285
Echinococcus granulosus tyrosine protein kinase Src64B 0.0013 0.0021 0.0023
Brugia malayi Thioredoxin reductase 0.0053 0.0197 0.0197
Schistosoma mansoni cytochrome P450 0.0018 0.0044 0.005
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Echinococcus multilocularis expressed protein 0.0037 0.0129 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi Cathepsin L-like precursor 0.0024 0.0071 0.0071
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0037 0.0126 0.0141
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0069 0.0069
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0045 0.0049
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.029 0.0324
Loa Loa (eye worm) hypothetical protein 0.007 0.0274 0.0274
Onchocerca volvulus Cell death protein 3 homolog 0.0027 0.0082 0.0081
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0082
Entamoeba histolytica cysteine protease, putative 0.0036 0.0124 0.0138
Echinococcus multilocularis ecdysone induced protein 78C 0.0133 0.055 0.0616
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) TK/ABL protein kinase 0.0013 0.0021 0.0021
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0152 0.0171
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus Chromo domain 0.0011 0.0014 0.0016
Echinococcus granulosus Tubulin beta 2C chain 0.2035 0.8921 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0044 0.0191
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0219 0.0927 0.1039
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.043 0.0482
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1534 0.6715 0.7528
Echinococcus multilocularis tubulin alpha 1C chain 0.1534 0.6715 0.7528
Schistosoma mansoni tyrosine kinase 0.0013 0.0021 0.0023
Schistosoma mansoni tubulin subunit alpha 0.0525 0.2274 0.255
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0114
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Giardia lamblia Beta tubulin 0.2035 0.8921 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0013 0.0021 0.0023
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0133 0.055 0.0616
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0466
Plasmodium vivax replication factor C subunit 1, putative 0.0011 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0065
Brugia malayi Cytochrome P450 family protein 0.0018 0.0044 0.0044
Echinococcus granulosus tubulin alpha 1C chain 0.1534 0.6715 0.7528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0013 0.0014
Brugia malayi Tubulin beta-1 chain 0.2035 0.8921 0.8921
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0079 0.0089
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0024 0.007 0.0078
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0024 0.007 0.0078
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0024 0.007 0.0304
Leishmania major cathepsin L-like protease 0.0036 0.0124 0.0138
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0274 0.0274
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0037 0.0041
Brugia malayi hypothetical protein 0.0043 0.0152 0.0152
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0152 0.017
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0184 0.0773 0.0867
Onchocerca volvulus 0.001 0.0006 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.043 0.0481
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0124 0.0139
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Echinococcus multilocularis Tubulin beta 2C chain 0.2035 0.8921 1
Brugia malayi nuclear receptor NHR-88 0.0063 0.024 0.024
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.007 0.0274 0.0307
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0006 0.0007
Brugia malayi Cell division protein ftsZ 0.0525 0.2274 0.2274
Echinococcus granulosus lamin 0.0027 0.0084 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.024 0.0269
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Trypanosoma brucei Metacaspase-4 0.0027 0.0082 0.0091
Schistosoma mansoni hypothetical protein 0.0067 0.0261 0.0293
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0057 0.0063
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0102 0.0114
Trichomonas vaginalis tubulin gamma chain, putative 0.0525 0.2274 0.255
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0133 0.055 0.0616
Echinococcus granulosus Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Echinococcus granulosus tubulin subunit beta 0.2035 0.8921 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0102 0.0102
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0045 0.005
Echinococcus granulosus BRK domain containing protein 0.0011 0.0014 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0044 0.0191
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0184 0.0773 0.0773
Echinococcus granulosus tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Trypanosoma brucei zeta tubulin 0.1622 0.7105 0.7964
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0039
Schistosoma mansoni steroid hormone receptor ad4bp 0.0133 0.055 0.0616
Entamoeba histolytica hypothetical protein 0.0219 0.0927 0.1038
Schistosoma mansoni coup transcription factor 0.0133 0.055 0.0616
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0022 0.0063 0.007
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0106 0.0118
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0399 0.0399
Plasmodium vivax vivapain-1 0.0019 0.0046 0.0051
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0018 0.0044 0.005
Plasmodium falciparum thioredoxin reductase 0.0018 0.0045 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0133 0.055 0.0616
Onchocerca volvulus 0.001 0.0006 0.0005
Trypanosoma cruzi alpha tubulin, putative 0.1534 0.6715 0.7527
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Brugia malayi nuclear hormone receptor family member odr-7 0.0063 0.024 0.024
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0046 0.0051
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0544 0.2387
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0152 0.017
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0024 0.007 0.0304
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Entamoeba histolytica tubulin family protein 0.2035 0.8921 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0022 0.0025
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0011 0.0013 0.0013
Echinococcus multilocularis tubulin alpha 1C chain 0.1534 0.6715 0.7528
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0107 0.0119
Schistosoma mansoni myoglobin 1 0.001 0.0006 0.0007
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0133 0.055 0.0616
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0013 0.0021 0.0023
Leishmania major beta tubulin 0.2035 0.8921 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0078 0.0338
Leishmania major epsilon tubulin, putative 0.1249 0.5464 0.6125
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0044 0.0191
Loa Loa (eye worm) endoplasmin 0.0032 0.0107 0.0107
Onchocerca volvulus 0.0013 0.0021 0.002
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0001 0.0001
Loa Loa (eye worm) globin family protein 0.001 0.0006 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0197 0.0221
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Schistosoma mansoni loxhd1 0.0043 0.0152 0.0171
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0001 0.0001
Plasmodium vivax heat shock protein 90, putative 0.0013 0.0022 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.029 0.0324
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0121 0.0496 0.218
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0065 0.0072
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0113
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0044 0.0191
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0063 0.024 0.0269
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0045 0.005
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0165 0.0165
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.024 0.0269
Trypanosoma brucei alpha tubulin 0.1534 0.6715 0.7527
Trichomonas vaginalis tubulin beta chain, putative 0.2035 0.8921 1
Entamoeba histolytica hypothetical protein 0.0219 0.0927 0.1038
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0107 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.0001 0.0001
Treponema pallidum cell division protein FtsZ 0.0525 0.2274 0.9064
Echinococcus granulosus dna polymerase eta 0.0053 0.0199 0.0223
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.0046 0.0052
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0039 0.0043
Leishmania major metacaspase, putative 0.0027 0.0082 0.0091
Brugia malayi cytochrome P450 0.0018 0.0044 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0133 0.055 0.055
Schistosoma mansoni tubulin subunit alpha 0.1534 0.6715 0.7528
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0022 0.0025
Leishmania major cathepsin L-like protease 0.0138 0.0573 0.0641
Trichomonas vaginalis tubulin, putative 0.062 0.2693 0.3018
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0037 0.0125 0.0139
Leishmania major beta tubulin 0.2035 0.8921 1
Echinococcus multilocularis dna polymerase eta 0.0053 0.0199 0.0223
Brugia malayi Tubulin alpha chain 0.1534 0.6715 0.6715
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0013 0.0021 0.0023
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0001 0.0001
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0044 0.0191
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0079 0.031 0.1362
Echinococcus granulosus WW domain containing oxidoreductase 0.0008 0.0001 0.0001
Giardia lamblia Delta tubulin 0.0525 0.2274 0.2549
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0017 0.0018
Echinococcus granulosus jun protein 0.0088 0.0351 0.0393
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0133 0.055 0.055
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0014 0.0015
Echinococcus granulosus intermediate filament protein 0.0027 0.0084 0.0094
Brugia malayi Nuclear hormone receptor E75 0.0063 0.024 0.024
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Toxoplasma gondii alpha-tubulin I, putative 0.1534 0.6715 0.7527
Leishmania major beta tubulin 0.2035 0.8921 1
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Brugia malayi Retinol dehydrogenase 12 0.0008 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0133 0.055 0.055
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0045 0.0049
Schistosoma mansoni hypothetical protein 0.0043 0.0152 0.0171
Schistosoma mansoni polycystin 1-related 0.0043 0.0152 0.0171
Trypanosoma cruzi DNA polymerase eta, putative 0.0053 0.0199 0.0222
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Plasmodium falciparum metacaspase 1 0.0027 0.0082 0.0091
Echinococcus multilocularis thyroid hormone receptor alpha 0.0274 0.1171 0.1313
Loa Loa (eye worm) hypothetical protein 0.0099 0.0399 0.0399
Schistosoma mansoni nuclear receptor 0.0063 0.024 0.0269
Trypanosoma cruzi metacaspase, putative 0.0027 0.0082 0.0091
Schistosoma mansoni rab6-interacting 0.0043 0.0152 0.0171
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0227 0.0996
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0017 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0039 0.0043
Loa Loa (eye worm) BRM protein 0.0042 0.015 0.015
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.029 0.0325
Onchocerca volvulus 0.0103 0.0416 0.0416
Brugia malayi RNA binding protein 0.0134 0.0555 0.0555
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0044 0.0191
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0014 0.0015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0133 0.055 0.0616
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0197 0.022
Loa Loa (eye worm) inositol-1 0.0039 0.0134 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0124 0.0139
Trypanosoma cruzi epsilon tubulin, putative 0.1249 0.5464 0.6125
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0017 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Echinococcus granulosus ecdysone induced protein 78C 0.0133 0.055 0.0616
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Treponema pallidum NADH oxidase 0.0018 0.0045 0.0129
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0129 0.0129
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0014 0.0016
Entamoeba histolytica tubulin family protein 0.2035 0.8921 1
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0107 0.012
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0024 0.007 0.0078
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0133 0.055 0.0616
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0573 0.0641
Trypanosoma cruzi cruzipain precursor, putative 0.0012 0.0017 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0046 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0046 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0045 0.0049
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0544 0.0609
Plasmodium falciparum replication factor C subunit 1, putative 0.0011 0.0013 0.0013
Plasmodium vivax vivapain-3 0.0019 0.0046 0.0051
Trichomonas vaginalis tubulin epsilon chain, putative 0.1534 0.6715 0.7528
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0133 0.055 0.0616
Echinococcus granulosus tyrosine kinase 0.0013 0.0021 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0065 0.0281
Entamoeba histolytica cysteine proteinase 1, putative 0.0019 0.0046 0.0051
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.005 0.0184 0.0206
Leishmania major cathepsin L-like protease 0.0036 0.0124 0.0138
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0063 0.007
Echinococcus granulosus Tubulin beta 2C chain 0.2035 0.8921 1
Onchocerca volvulus 0.0028 0.0086 0.0085
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0544 0.2387
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0124 0.0124
Brugia malayi hypothetical protein 0.0219 0.0927 0.0927
Leishmania major trypanothione reductase 0.0053 0.0197 0.022
Echinococcus granulosus tubulin subunit TubB 0.1534 0.6715 0.7528
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0103 0.0416 0.0467
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0001 0.0001
Echinococcus granulosus heat shock protein 90 0.0026 0.0078 0.0087
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0024 0.007 0.0304
Echinococcus granulosus nibrin 0.0011 0.0013 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0152 0.0171
Echinococcus multilocularis caspase 2 0.0027 0.0082 0.0092
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0133 0.055 0.0616
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus microtubule associated protein 2 0.0667 0.2899 0.325
Loa Loa (eye worm) alpha-tubulin 0.1534 0.6715 0.6715
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0013 0.0021 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0044 0.0191
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0399 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0067 0.0261 0.0261
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0088 0.0351 0.0393
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0044 0.0191
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0057 0.0063
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0048 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0079 0.0312 0.035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0082 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0227 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Echinococcus multilocularis lamin 0.0027 0.0084 0.0094
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0282 0.1207 0.5304
Echinococcus multilocularis FTZ F1 alpha 0.0133 0.055 0.0616
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0044 0.0191
Schistosoma mansoni cathepsin s 0.0012 0.0017 0.0019
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.029 0.0324
Loa Loa (eye worm) hypothetical protein 0.0648 0.2815 0.2815
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.097 0.1087
Echinococcus granulosus tubulin beta 1 chain 0.2035 0.8921 1
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0022 0.0024
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0013 0.0013
Entamoeba histolytica Ran family GTPase 0.0024 0.0069 0.0076
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0134 0.0149
Brugia malayi Globin family protein 0.001 0.0006 0.0006
Giardia lamblia Guanine phosphoribosyltransferase 0.0103 0.0416 0.0466
Leishmania major DNA polymerase kappa, putative 0.0017 0.0037 0.0041
Brugia malayi Endoplasmin precursor 0.0032 0.0107 0.0107
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0114
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0036 0.0124 0.0138
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0017 0.0019
Echinococcus multilocularis 0.0018 0.0044 0.005
Echinococcus multilocularis tyrosine protein kinase Abl 0.0013 0.0021 0.0023
Brugia malayi nuclear receptor NHR-88 0.0133 0.055 0.055
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.0544 0.0609
Leishmania major delta tubulin, putative 0.1181 0.5164 0.5788
Plasmodium falciparum metacaspase-like protein 0.0027 0.0082 0.0091
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0078 0.0087
Onchocerca volvulus 0.001 0.0006 0.0005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0102 0.0102
Leishmania major importin beta-1 subunit, putative 0.0026 0.0079 0.0088
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0044 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0121 0.0496 0.218
Mycobacterium ulcerans hypothetical protein 0.0017 0.0037 0.0159
Schistosoma mansoni topbp1 0.0011 0.0013 0.0014
Schistosoma mansoni cpg binding protein 0.0028 0.0086 0.0097
Schistosoma mansoni ran 0.0024 0.0069 0.0077
Brugia malayi Tubulin gamma chain 0.1251 0.5471 0.5471
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0023 0.0065 0.0281
Toxoplasma gondii exonuclease III APE 0.0021 0.0057 0.0063
Brugia malayi MH2 domain containing protein 0.0119 0.0488 0.0488
Trichomonas vaginalis tubulin, putative 0.2035 0.8921 1
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0124 0.0124
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0124 0.0138
Loa Loa (eye worm) BEN-1 protein 0.2035 0.8921 0.8921
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0039
Plasmodium vivax metacaspase 1, putative 0.0027 0.0082 0.0091
Mycobacterium leprae cell division protein FtsZ 0.0525 0.2274 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0121 0.0496 0.218
Brugia malayi nuclear hormone receptor 0.0133 0.055 0.055
Schistosoma mansoni jun-related protein 0.0071 0.0278 0.0312
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0133 0.055 0.0616
Onchocerca volvulus 0.0013 0.0021 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0065 0.0072
Onchocerca volvulus 0.0015 0.003 0.003
Loa Loa (eye worm) cysteine protease 0.0036 0.0124 0.0124
Schistosoma mansoni inositol monophosphatase 0.0039 0.0134 0.015
Schistosoma mansoni hypothetical protein 0.001 0.0006 0.0007
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0084 0.0084
Loa Loa (eye worm) BEN-1 protein 0.2035 0.8921 0.8921
Toxoplasma gondii tubulin, putative 0.0105 0.0425 0.0475
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.029 0.0324
Mycobacterium tuberculosis Cell division protein FtsZ 0.0525 0.2274 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0065 0.0281
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Echinococcus granulosus tyrosine protein kinase Fyn 0.0013 0.0021 0.0023
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0197 0.0221
Echinococcus granulosus Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0036 0.0124 0.0138
Plasmodium vivax tubulin alpha chain, putative 0.1534 0.6715 0.7527
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0134 0.0149
Entamoeba histolytica hypothetical protein 0.0219 0.0927 0.1038
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0134 0.0586
Leishmania major beta tubulin 0.2035 0.8921 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.029 0.029
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0044 0.0049
Onchocerca volvulus 0.0036 0.0124 0.0123
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Brugia malayi heat shock protein 90 0.0032 0.0107 0.0107
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0017 0.0017
Mycobacterium tuberculosis Probable reductase 0.0121 0.0496 0.218
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0053 0.0199 0.0223
Brugia malayi BRM protein 0.0066 0.0255 0.0255
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0069 0.0076
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0057 0.0246
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0057 0.0064
Giardia lamblia Adenine phosphoribosyltransferase 0.0024 0.007 0.0077
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0114
Schistosoma mansoni tubulin subunit beta 0.2035 0.8921 1
Echinococcus granulosus uridine 5' monophosphate synthase 0.0024 0.007 0.0078
Brugia malayi Hsp90 protein 0.0013 0.0022 0.0022
Brugia malayi Tubulin beta chain 0.062 0.2693 0.2693
Echinococcus multilocularis tubulin gamma 1 chain 0.1251 0.5471 0.6133
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0094 0.0104
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Echinococcus multilocularis caspase 0.0027 0.0082 0.0092
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0045 0.0194
Schistosoma mansoni lamin 0.0027 0.0084 0.0094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0039 0.0039
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0024 0.007 0.0077
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Schistosoma mansoni helicase 0.0066 0.0255 0.0285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0046 0.0051
Trichomonas vaginalis tubulin, putative 0.0631 0.2742 0.3074
Schistosoma mansoni hypothetical protein 0.0359 0.1545 0.1732
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.0021 0.0021
Onchocerca volvulus 0.0036 0.0124 0.0123
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0014 0.0015
Trypanosoma brucei epsilon tubulin 0.1249 0.5464 0.6125
Loa Loa (eye worm) tubulin alpha chain 0.1534 0.6715 0.6715
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0124 0.0123
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi polk-prov protein 0.0042 0.015 0.015
Onchocerca volvulus 0.001 0.0006 0.0005
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0088 0.0351 0.0393
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0013 0.0014
Brugia malayi alpha-tubulin 0.1534 0.6715 0.6715
Plasmodium falciparum alpha tubulin 1 0.1534 0.6715 0.7527
Trypanosoma brucei polo-like protein kinase 0.0106 0.043 0.0481
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0133 0.055 0.055
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0045 0.0049
Schistosoma mansoni alpha tubulin 0.1534 0.6715 0.7528
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0024 0.007 0.007
Loa Loa (eye worm) RNA binding protein 0.0134 0.0555 0.0555
Entamoeba histolytica cysteine protease, putative 0.0019 0.0046 0.0051
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0045 0.0049
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0107 0.0119
Onchocerca volvulus 0.0063 0.024 0.024
Echinococcus granulosus Tubulin beta 2C chain 0.2035 0.8921 1
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Onchocerca volvulus 0.0024 0.0071 0.007
Trypanosoma cruzi tubulin gamma chain 0.1251 0.5471 0.6132
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0037 0.0041
Echinococcus multilocularis peroxisome assembly protein 26 0.1534 0.6715 0.7528
Brugia malayi hypothetical protein 0.0011 0.0013 0.0013
Trypanosoma brucei alpha tubulin 0.1534 0.6715 0.7527
Entamoeba histolytica tubulin alpha chain, putative 0.1534 0.6715 0.7527
Echinococcus granulosus heat shock protein 0.0032 0.0107 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Echinococcus multilocularis Tubulin beta 2C chain 0.2035 0.8921 1
Echinococcus granulosus dna polymerase kappa 0.0079 0.0312 0.035
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0152 0.0171
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0084 0.0084
Brugia malayi conserved hypotetical protein 0.0063 0.024 0.024
Echinococcus multilocularis tyrosine kinase 0.0013 0.0021 0.0023
Schistosoma mansoni globin X 0.001 0.0006 0.0007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0057 0.0063
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0014 0.0015
Schistosoma mansoni hypothetical protein 0.0071 0.0278 0.0312
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0107 0.0119
Leishmania major DNA polymerase eta, putative 0.0053 0.0199 0.0222
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0063 0.024 0.0269
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0071 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0046 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0195 0.0218
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0184 0.0773 0.0866
Echinococcus granulosus tyrosine protein kinase Lyn 0.0013 0.0022 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.043 0.0482
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0008 0.0001 0.0001
Trichomonas vaginalis tubulin epsilon chain, putative 0.1534 0.6715 0.7528
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0078 0.0338
Brugia malayi Steroid receptor seven-up type 2 0.0133 0.055 0.055
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0103 0.0416 0.1827
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0057 0.0063
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0102 0.0102
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0001 0.0001
Trichomonas vaginalis DNA polymerase eta, putative 0.0079 0.0312 0.035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0017
Trypanosoma cruzi epsilon tubulin, putative 0.1249 0.5464 0.6125
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Schistosoma mansoni zinc finger protein 0.0063 0.024 0.0269
Leishmania major hypothetical protein, conserved 0.005 0.0184 0.0206
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Mycobacterium ulcerans monooxygenase 0.001 0.0006 0.0022
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0124 0.0138
Brugia malayi orotate phosphoribosyltransferase family protein 0.0024 0.007 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0063 0.024 0.024
Echinococcus multilocularis Tubulin alpha 1 chain 0.1534 0.6715 0.7528
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0044 0.0191
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0416 0.0466
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0121 0.0496 0.218
Leishmania major alpha tubulin 0.1534 0.6715 0.7527
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0573 0.0641
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0134 0.0556 0.2441
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.015 0.0167
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0044 0.0191
Trypanosoma cruzi metacaspase, putative 0.0027 0.0082 0.0091
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0082 0.0092
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0197 0.0865
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1145 0.5003 0.5608
Echinococcus granulosus tubulin alpha 3 chain 0.1534 0.6715 0.7528
Schistosoma mansoni nuclear hormone receptor 0.0063 0.024 0.0269
Echinococcus multilocularis Tubulin beta 2C chain 0.2035 0.8921 1
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0063 0.024 0.024
Leishmania major cytochrome p450-like protein 0.0018 0.0044 0.0049
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0039 0.0169
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0133 0.055 0.0616
Trichomonas vaginalis tubulin, putative 0.062 0.2693 0.3018
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0488 0.0488
Schistosoma mansoni lipoxygenase 0.0179 0.0751 0.0842
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0169 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0124 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0312 0.0349
Leishmania major DNA polymerase eta, putative 0.0017 0.0037 0.0041
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0146 0.0146
Echinococcus granulosus beta tubulin 0.2035 0.8921 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.0092
Schistosoma mansoni heat shock protein 0.0032 0.0107 0.012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Schistosoma mansoni DNA polymerase eta 0.0053 0.0199 0.0223
Brugia malayi Cathepsin L-like precursor 0.0036 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0032 0.0106 0.0106
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0107 0.0119
Echinococcus granulosus beta tubulin 0.2035 0.8921 1
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0078 0.0087
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0001 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0082 0.0091
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0063 0.024 0.0269
Onchocerca volvulus 0.0043 0.0152 0.0151
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0045 0.005
Schistosoma mansoni terminal deoxycytidyl transferase 0.0053 0.0199 0.0223
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0008 0.0001 0.0001
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis tubulin beta chain, putative 0.1534 0.6715 0.7528
Mycobacterium tuberculosis Conserved protein 0.0024 0.007 0.0304
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0184 0.0773 0.0773
Plasmodium vivax DNA repair protein REV1, putative 0.0017 0.0037 0.0041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0069 0.0076
Brugia malayi Protein kinase domain containing protein 0.0013 0.0021 0.0021
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0024 0.007 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0013 0.0014
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0045 0.005
Trypanosoma brucei alpha tubulin, putative 0.062 0.2693 0.3018
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0022 0.0025
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.2508 0.2811
Echinococcus multilocularis tumor protein p63 0.0379 0.1632 0.1829
Loa Loa (eye worm) tubulin beta-1 chain 0.2035 0.8921 0.8921
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0024 0.007 0.0304
Brugia malayi isocitrate dehydrogenase 0.0031 0.0102 0.0102
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0006 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0485 0.2097 0.2097
Echinococcus granulosus tubulin alpha 3 chain 0.1534 0.6715 0.7528
Schistosoma mansoni hypothetical protein 0.0011 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0133 0.055 0.055
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0125 0.0139
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.2899 0.325
Leishmania major heat shock protein 83-1 0.0032 0.0107 0.0119
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0045 0.0049
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0141 0.0585 0.0656
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0124 0.0139
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Brugia malayi hypothetical protein 0.0063 0.024 0.024
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0103 0.0416 0.0466
Plasmodium vivax vivapain-2 0.0036 0.0124 0.0138
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0024 0.007 0.0078
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0133 0.055 0.055
Echinococcus multilocularis cathepsin L 0.0019 0.0046 0.0052
Schistosoma mansoni nuclear receptor nhr-48 0.0063 0.024 0.0269
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0195 0.0218
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0274 0.0274
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0017 0.0019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0086 0.0097
Echinococcus granulosus Tubulin beta 2C chain 0.2035 0.8921 1
Plasmodium vivax importin-beta 2, putative 0.0032 0.0106 0.0118
Leishmania major cytochrome p450-like protein 0.0046 0.0165 0.0184
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Trichomonas vaginalis tubulin beta chain, putative 0.062 0.2693 0.3018
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0133 0.055 0.0549
Schistosoma mansoni importin beta-1 0.0032 0.0106 0.0119
Trypanosoma brucei heat shock protein, putative 0.0032 0.0107 0.0119
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0227 0.0254
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) ctsf protein 0.0036 0.0124 0.0124
Loa Loa (eye worm) dehydrogenase 0.0008 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 334 nM Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured after 1 hr in presence of [gamma-33P]ATP by scintillation counting analysis ChEMBL. 25262541
IC50 (binding) = 2225 nM Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured after 1 hr in presence of [gamma-33P]ATP by scintillation counting analysis ChEMBL. 25262541
IC50 (binding) = 4410 nM Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured after 1 hr in presence of [gamma-33P]ATP by scintillation counting analysis ChEMBL. 25262541

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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