Detailed information for compound 1337188

Basic information

Technical information
  • TDR Targets ID: 1337188
  • Name: 5-[(4-diethylaminophenyl)methylidene]-1-(oxol an-2-ylmethyl)-1,3-diazinane-2,4,6-trione
  • MW: 371.43 | Formula: C20H25N3O4
  • H donors: 1 H acceptors: 3 LogP: 2.41 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(c1ccc(cc1)/C=C\1/C(=O)NC(=O)N(C1=O)CC1CCCO1)CC
  • InChi: 1S/C20H25N3O4/c1-3-22(4-2)15-9-7-14(8-10-15)12-17-18(24)21-20(26)23(19(17)25)13-16-6-5-11-27-16/h7-10,12,16H,3-6,11,13H2,1-2H3,(H,21,24,26)/b17-12-
  • InChiKey: JMMZNRHHHLCSTO-ATVHPVEESA-N  


Substructure search Similarity search

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Synonyms

  • (5Z)-5-[(4-diethylaminophenyl)methylidene]-1-(oxolan-2-ylmethyl)-1,3-diazinane-2,4,6-trione
  • 5-[(4-diethylaminophenyl)methylene]-1-(tetrahydrofuran-2-ylmethyl)hexahydropyrimidine-2,4,6-trione
  • (5Z)-5-[(4-diethylaminophenyl)methylene]-1-(tetrahydrofuran-2-ylmethyl)hexahydropyrimidine-2,4,6-trione
  • (5Z)-5-[(4-diethylaminophenyl)methylene]-1-(2-tetrahydrofuranylmethyl)hexahydropyrimidine-2,4,6-trione
  • 5-[(4-diethylaminophenyl)methylene]-1-(2-tetrahydrofuranylmethyl)hexahydropyrimidine-2,4,6-trione
  • 5-(4-diethylaminobenzylidene)-1-(tetrahydrofurfuryl)barbituric acid
  • (5Z)-5-(4-diethylaminobenzylidene)-1-(tetrahydrofurfuryl)barbituric acid
  • MLS000575742
  • SMR000196778
  • 5-[4-(diethylamino)benzylidene]-1-(tetrahydro-2-furanylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0054 0.0054
Echinococcus multilocularis serine threonine protein kinase 0.0011 0.0005 0.0005
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0094 0.0502 0.2372
Echinococcus granulosus mitogen activated protein kinase 11 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus protein kinase c epsilon type 0.0011 0.0005 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0112 0.0509
Echinococcus granulosus casein kinase i 0.0049 0.0235 0.0235
Schistosoma mansoni tyrosine kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0338 0.1591
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/DAPK/DAPK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis casein kinase I gamma 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 9 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase SIK3 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi intracellular kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase greatwall 0.0011 0.0005 0.0005
Echinococcus granulosus citron Rho interacting kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi cdc2-related kinase 3 0.0363 0.2099 1
Loa Loa (eye worm) CDC7 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus casein kinase I gamma 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0094 0.0502 0.0502
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0281 0.0281
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0011 0.0005 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0059 0.0258
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0059 0.0059
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase C05D10.2 in chromosome III 0.0011 0.0005 0.0005
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.008 0.0358
Echinococcus multilocularis serine:threonine protein kinase MAK 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0011 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0059 0.5
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.008 0.008
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1694 1 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0049 0.0235 0.0235
Schistosoma mansoni myotonic dystrophy kinase-related cdc42-binding kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Toxoplasma gondii casein kinase I 0.0049 0.0235 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0037 0.0159 0.0159
Schistosoma mansoni MAGUK homolog 0.0011 0.0005 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0112 0.0509
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0129 0.0129
Echinococcus granulosus serine:threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0235 0.0235
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0054 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus eukaryotic translation initiation factor 2 alpha 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase sperm-specific MAP kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKN protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity mitogen activated protein 0.0094 0.0502 0.0502
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0054 0.0054
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0011 0.0005 0.0005
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0059 0.0258
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus ribosomal protein S6 kinase delta 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0011 0.0005 0.0005
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0011 0.0005 0.0005
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase C mu 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cell cycle related kinase 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei casein kinase I, isoform 2 0.0049 0.0235 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus microtubule associated protein 2 0.0833 0.4891 0.4891
Loa Loa (eye worm) AGC/NDR protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0035 0.0148 0.0148
Echinococcus granulosus casein kinase I alpha 0.0049 0.0235 0.0235
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0011 0.0005 0.0005
Brugia malayi cyclin-dependent kinase 9 0.0011 0.0005 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0281 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) NEK protein kinase 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus NDR protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Brugia malayi HLS7-interacting protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei polo-like protein kinase 0.0124 0.068 0.3225
Echinococcus granulosus serine:threonine protein kinase N2 0.0011 0.0005 0.0005
Echinococcus multilocularis tau tubulin kinase 1 0.0011 0.0005 0.0005
Echinococcus granulosus protein kinase C gamma type 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus beta-adrenergic receptor kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0011 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0054 0.0234
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus cpg binding protein 0.0037 0.0159 0.0159
Schistosoma mansoni serine/threonine kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Onchocerca volvulus 0.0165 0.092 0.9351
Loa Loa (eye worm) PEK/PEK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus G protein coupled receptor kinase 1 0.0011 0.0005 0.0005
Brugia malayi activin receptor:ISOTYPE=IIA. 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0049 0.0235 0.0235
Trichomonas vaginalis STE family protein kinase 0.0094 0.0502 0.2372
Loa Loa (eye worm) CAMK/CASK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE7/MEK4 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 0.0363 0.2099 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 0.0363 0.2099 0.2099
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/STLK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0066 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.008 0.0358
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase LATS2 0.0011 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0375 0.0375
Echinococcus multilocularis TBC domain containing protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK4 protein kinase 0.0011 0.0005 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0112 0.0509
Giardia lamblia Kinase, CMGC CDK 0.0363 0.2099 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis rac serine:threonine kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0005
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.0011 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0494 0.2875 0.2875
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0059 0.1453
Trypanosoma cruzi polo-like protein kinase, putative 0.0124 0.068 0.3225
Echinococcus granulosus serine:threonine protein kinase 11 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0124 0.068 0.068
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0011 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0377 1
Brugia malayi CASK 0.0011 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0037 0.0159 0.0159
Schistosoma mansoni sodium/chloride dependent transporter 0.0011 0.0005 0.0005
Schistosoma mansoni dual specificity serine/threonine tyrosine kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0124 0.068 0.3225
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0062 0.0712
Echinococcus granulosus casein kinase ii subunit alpha 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0011 0.0005 0.0005
Plasmodium falciparum casein kinase 1 0.0049 0.0235 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.2099 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis rho associated protein kinase 1 0.0011 0.0005 0.0005
Onchocerca volvulus 0.0039 0.0172 0.1702
Schistosoma mansoni dual specificity kinase 0.0011 0.0005 0.0005
Brugia malayi cell division control protein 2 homolog 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Giardia lamblia Kinase, CK1 Casein kinase 0.0049 0.0235 0.1098
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 7 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Plasmodium falciparum glutathione reductase 0.002 0.0059 0.0258
Loa Loa (eye worm) AUR protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.008 0.008
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 7 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trichomonas vaginalis STE family protein kinase 0.0094 0.0502 0.2372
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0059 0.8501
Echinococcus multilocularis casein kinase I delta 0.0049 0.0235 0.0235
Echinococcus granulosus cyclin dependent kinase 17 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni peptidase 0.0011 0.0005 0.0005
Echinococcus multilocularis cpg binding protein 0.0037 0.0159 0.0159
Echinococcus granulosus cyclin dependent kinase 16 0.0011 0.0005 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0059 0.0059
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0094 0.0502 0.0502
Echinococcus multilocularis mitogen activated protein kinase 14 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, putative 0.0049 0.0235 0.1098
Echinococcus multilocularis TGF beta receptor type 1 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0019 0.0054 0.0054
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Plasmodium falciparum glutathione reductase 0.0057 0.0281 0.1317
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dna polymerase eta 0.0023 0.008 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0338 0.1591
Loa Loa (eye worm) AGC/NDR protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0069
Echinococcus multilocularis cyclin dependent kinase 1 0.0363 0.2099 0.2099
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0005 0.0005
Entamoeba histolytica casein kinase, putative 0.0049 0.0235 0.1098
Brugia malayi glutathione reductase 0.0057 0.0281 0.0281
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0054 0.0054
Loa Loa (eye worm) IRE protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus 5'partial|STE20 kinase adapter protein beta 0.0011 0.0005 0.0005
Echinococcus multilocularis STE20:SPS1 proline alanine rich protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.0011 0.0005 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0059 0.0258
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase NLK 0.0011 0.0005 0.0005
Brugia malayi C1-like domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase 15 0.0011 0.0005 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0069 0.171
Trichomonas vaginalis CK1 family protein kinase 0.0049 0.0235 0.1098
Echinococcus granulosus cyclin dependent kinase 11B 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase K06H7.1 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0066 0.0066
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0715 0.8916
Echinococcus granulosus serine:threonine protein kinase 17A 0.0011 0.0005 0.0005
Echinococcus multilocularis Serine:threonine protein kinase PRP4 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity protein kinase clk2 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0332 0.1561
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0802 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase ZK507.1 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0715 0.8916
Brugia malayi MGC81364 protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) AUR protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0054 0.0054
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis vaccinia related kinase 1 0.0011 0.0005 0.0005
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0281 0.1317
Loa Loa (eye worm) NAK/GAK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis Serine:threonine protein kinase PFTAIRE 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0069
Brugia malayi P38 map kinase family protein 2 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKG protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0037 0.0153
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0059 0.0679
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0005 0.0005
Echinococcus granulosus NDR protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0069 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0011 0.0005 0.0005
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0094 0.0502 0.2372
Schistosoma mansoni dual specificity kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE11/MEKK4 protein kinase 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.008 0.2015
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0005 0.0005
Plasmodium falciparum protein kinase 5 0.0363 0.2099 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0054 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Brugia malayi Ribonuclease 2-5A family protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0011 0.0005 0.0005
Brugia malayi Cam kinase protein 1 0.0011 0.0005 0.0005
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi serine/threonine protein kinase 6 0.0011 0.0005 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0059 0.1453
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0062 0.0712
Loa Loa (eye worm) IKK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Ser/Thr kinase. 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/AKT protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0377 0.4671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0054 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/LKB protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0011 0.0005 0.0005
Onchocerca volvulus 0.0175 0.0983 1
Loa Loa (eye worm) CMGC/RCK/MAK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) glutathione reductase 0.0057 0.0281 0.0281
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0983 0.0983
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0019 0.0054 0.0054
Echinococcus multilocularis agc family protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0054 0.0054
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0005
Echinococcus granulosus tau tubulin kinase 1 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable reductase 0.013 0.0715 0.8916
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis rho associated protein kinase 0.0175 0.0983 0.0983
Echinococcus multilocularis dna polymerase kappa 0.0023 0.008 0.008
Loa Loa (eye worm) AGC/YANK protein kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CK1 family protein kinase 0.0049 0.0235 0.1098
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis wee1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) SCY1 protein kinase 0.0011 0.0005 0.0005
Brugia malayi cyclin-dependent kinase 7 homolog 0.0011 0.0005 0.0005
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0059 0.0258
Brugia malayi Hr1 repeat family protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0054 0.0234
Onchocerca volvulus 0.0029 0.0112 0.109
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Echinococcus multilocularis serine:threonine protein kinase 17A 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.008 0.0358
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi cdc2-related kinase 1 0.0363 0.2099 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0112 0.0509
Echinococcus granulosus serine:threonine protein kinase ULK3 0.0011 0.0005 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0124 0.068 0.3225
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0363 0.2099 0.2099
Echinococcus granulosus mitogen activated protein kinase 14 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/DAPK/DAPK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0019 0.0054 0.0234
Loa Loa (eye worm) CAMKK/META protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0377 0.0377
Brugia malayi Pctaire class cell cycle kinase protein 1 0.0011 0.0005 0.0005
Leishmania major casein kinase, putative 0.0049 0.0235 0.1098
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi casein kinase I 0.0049 0.0235 0.0235
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0363 0.2099 1
Echinococcus multilocularis cyclin dependent kinase 10 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi protein kinase C II. 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase plk-2 0.0124 0.068 0.068
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0377 0.0377
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0363 0.0363
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase C07A9.3 0.0011 0.0005 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0059 0.0258
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus Serine:threonine protein kinase PRP4 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Echinococcus multilocularis death associated protein kinase 1 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 1 0.0011 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase SIK1 0.0011 0.0005 0.0005
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 36 0.0011 0.0005 0.0005
Echinococcus granulosus CDC7 cell division cycle 7 0.0011 0.0005 0.0005
Leishmania major DNA polymerase kappa, putative 0.0023 0.008 0.0358
Loa Loa (eye worm) TBCK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0011 0.0005 0.0005
Entamoeba histolytica casein kinase 1, putative 0.0049 0.0235 0.1098
Echinococcus granulosus expressed protein 0.0011 0.0005 0.0005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.008 0.0358
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0124 0.068 0.3225
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity mitogen activated protein 0.0094 0.0502 0.0502
Echinococcus granulosus serine threonine protein kinase sik 0.0011 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0363 0.2099 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Plasmodium vivax glutathione reductase, putative 0.0057 0.0281 0.1317
Loa Loa (eye worm) protein kinase domain-containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis agc family protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase ULK4 0.0011 0.0005 0.0005
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.008 0.0358
Echinococcus granulosus dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase tousled 0.0011 0.0005 0.0005
Schistosoma mansoni cAMP-dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.008 0.008
Trypanosoma brucei cdc2-related kinase 1 0.0363 0.2099 1
Echinococcus multilocularis dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase ULK2 0.0011 0.0005 0.0005
Brugia malayi FMRFamide related peptide family protein 0.0011 0.0005 0.0005
Onchocerca volvulus 0.0049 0.0235 0.2351
Echinococcus multilocularis mitogen activated protein kinase 11 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trichomonas vaginalis STE family protein kinase 0.0094 0.0502 0.2372
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0011 0.0005 0.0005
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0112 0.0509
Brugia malayi Neuronal symmetry protein 1 0.0011 0.0005 0.0005
Echinococcus granulosus agc family protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.008 0.0358
Schistosoma mansoni P38 MAPk 0.0011 0.0005 0.0005
Echinococcus granulosus cell cycle related kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0054 0.0054
Loa Loa (eye worm) NRBP protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase WNK1 0.0011 0.0005 0.0005
Echinococcus granulosus wee1 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni titin 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis agc family protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dnaJ subfamily B 0.0494 0.2875 0.2875
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0011 0.0005 0.0005
Brugia malayi Cell division protein kinase 2 0.0011 0.0005 0.0005
Echinococcus multilocularis kinase protein 0.0011 0.0005 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0377 0.0377
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.008 0.0358
Schistosoma mansoni P21-activated kinase pak 0.0011 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0377 1
Echinococcus multilocularis eukaryotic translation initiation factor 2 alpha 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0054 0.0054
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis 0.0011 0.0005 0.0005
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0363 0.2099 0.2099
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus titin 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase C mu 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus casein kinase I delta 0.0049 0.0235 0.0235
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Loa Loa (eye worm) WEE protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni cGMP-dependent protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus granulosus protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Echinococcus granulosus TGF beta receptor type 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0353 0.2035 0.2035
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0059 0.0258
Echinococcus multilocularis cyclin dependent kinase 5 0.0363 0.2099 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Onchocerca volvulus Serine\/threonine kinase homolog 0.0124 0.068 0.6903
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 5 0.0363 0.2099 0.2099
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0375 0.0375
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) VPS15 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 11 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) ULK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis CDC7 cell division cycle 7 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/VRK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis casein kinase I alpha 0.0049 0.0235 0.0235
Brugia malayi putative serine/threonine kinase SADA gamma 0.0011 0.0005 0.0005
Brugia malayi STE20-like kinase MST 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0049 0.0235 0.1098
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.008 0.2015
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase F42G10.2 0.0011 0.0005 0.0005
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus tau tubulin kinase 1 0.0011 0.0005 0.0005
Schistosoma mansoni kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Mitogen-activated protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Dual specificity mitogen-activated protein kinase kinase 7. -TRUNCATED- 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Germinal center kinase family protein 1 0.0011 0.0005 0.0005
Trypanosoma brucei trypanothione reductase 0.0057 0.0281 0.1317
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus agc family protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.4891 0.4891
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0011 0.0005 0.0005
Brugia malayi cell division protein kinase 10 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0112 0.2865
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0059 0.0258
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0054 0.0054
Brugia malayi KIAA0303 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine threonine protein kinase nrc 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis kinase protein 0.0011 0.0005 0.0005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.008 0.008
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0049 0.0235 0.0235
Echinococcus granulosus serine:threonine protein kinase N2 0.0011 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0363 0.2099 1
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) PEK/HRI protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 36 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0363 0.0363
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.008 0.008
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0054 0.0054
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0011 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0112 0.2865
Echinococcus granulosus mitogen activated protein kinase 3 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis casein kinase i 0.0049 0.0235 0.0235
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi cdc2-related kinase 1 0.0363 0.2099 1
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 9 0.0011 0.0005 0.0005
Brugia malayi glycogen synthase kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase c protein 2 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0037 0.0153
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0281 0.3461
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0054 0.0054
Echinococcus multilocularis casein kinase I alpha 0.0049 0.0235 0.0235
Echinococcus granulosus protein kinase c iota type 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0059 0.0258
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0054 0.0234
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0523 0.3048 0.3048
Echinococcus granulosus protein kinase shaggy 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0016 0.0037 0.0153
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0011 0.0005 0.0005
Echinococcus granulosus TGF-beta receptor type-1 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis casein kinase I delta 0.0049 0.0235 0.0235
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0062 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0049 0.0235 0.0235
Trypanosoma brucei cdc2-related kinase 3 0.0363 0.2099 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0059 0.1453
Loa Loa (eye worm) STE/STE20/FRAY protein kinase 0.0011 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0049 0.0235 0.1099
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis glycogen synthase kinase 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Dual specificity mitogen-activated protein kinase kinase 6 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0019 0.0054 0.0054
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0049 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 11B 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0011 0.0005 0.0005
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0054 0.0054
Echinococcus multilocularis casein kinase ii subunit alpha 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis agc family protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0049 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0059 0.0258
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus rho-associated protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0715 0.8916
Loa Loa (eye worm) CMGC/CDK/CDK10 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase MAK 0.0011 0.0005 0.0005
Echinococcus multilocularis STE20 kinase adapter protein beta 0.0011 0.0005 0.0005
Echinococcus granulosus scy1 protein 2 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0073 0.0375 0.0375
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0059 0.0258
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0715 0.8916
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity serine:threonine tyrosine 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0059 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/DYRK/PRP4 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus granulosus titin 0.0011 0.0005 0.0005
Brugia malayi glycogen synthase kinase 3 alpha 0.0011 0.0005 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0375 0.0375
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0112 0.2865
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0011 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0054 0.0054
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 7 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni MAPk 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 3 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0798 0.0798
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi protein unc-22 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni atypical protein kinase C 0.0011 0.0005 0.0005
Echinococcus granulosus eukaryotic translation initiation factor 2 alpha 0.0011 0.0005 0.0005
Brugia malayi MAP kinase sur-1 0.0011 0.0005 0.0005
Echinococcus granulosus cGMP dependent protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase K06H7.1 0.0011 0.0005 0.0005
Brugia malayi cell division control protein 2 homolog 0.0011 0.0005 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0379 0.0379
Loa Loa (eye worm) TTK protein kinase 0.0011 0.0005 0.0005
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0112 0.2865
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0059 0.0258
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0363 0.2099 0.2099
Brugia malayi Calcium/calmodulin-dependent serine/threonine-protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis expressed conserved protein 0.0011 0.0005 0.0005
Brugia malayi Doublecortin family protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase SIK3 0.0011 0.0005 0.0005
Loa Loa (eye worm) cmgc/cdk/pitslre protein kinase 0.0011 0.0005 0.0005
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0054 0.0234
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0094 0.0502 0.0502
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.008 0.0358
Echinococcus granulosus cyclin dependent kinase 19 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi serine/threonine kinase 12 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase tousled 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis nuclear receptor binding protein 0.0011 0.0005 0.0005
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 10 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.008 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity protein kinase clk2 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase SIK1 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0069
Echinococcus granulosus AP2 associated protein kinase 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni ste20-related kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis protein KINase family member (kin 1) 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0011 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0377 1
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0011 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0059 0.5
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0377 0.0377
Echinococcus multilocularis citron Rho interacting kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 1 0.0363 0.2099 0.2099
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0112 0.2865
Loa Loa (eye worm) TKL/LISK/TESK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 15 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0112 0.1338
Leishmania major trypanothione reductase 0.0057 0.0281 0.1317
Echinococcus multilocularis cyclin g associated kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0112 0.2865
Entamoeba histolytica cell division protein kinase 2, putative 0.0363 0.2099 1
Echinococcus multilocularis cyclin dependent kinase 19 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus agc family protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis calcium activated potassium channel 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) TKL/MLK/MLK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi RWD domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) NEK/NEK8 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Giardia lamblia Kinase, STE STE20 0.0094 0.0502 0.2372
Loa Loa (eye worm) WNK protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0059 0.0258
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus 3'partial|mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Leishmania major DNA polymerase eta, putative 0.0023 0.008 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0023 0.008 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0112 0.0112
Echinococcus multilocularis dna polymerase eta 0.0023 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0112
Loa Loa (eye worm) STE/STE7/MEK3 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/SNRK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 1 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase SULU 0.0011 0.0005 0.0005
Echinococcus multilocularis protein kinase c epsilon type 0.0011 0.0005 0.0005
Brugia malayi protein kinase C3,putative 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, putative 0.0049 0.0235 0.1098
Brugia malayi Stress-activated protein kinase jnk-1 0.0011 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0049 0.0235 0.1099
Schistosoma mansoni kinase 0.0011 0.0005 0.0005
Brugia malayi Casein kinase II, alpha chain 0.0011 0.0005 0.0005
Echinococcus multilocularis serine threonine protein kinase sik serine threonine protein kinase par 0.0011 0.0005 0.0005
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0069 0.0304
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0112 0.1338
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Entamoeba histolytica cell division protein kinase 2, putative 0.0363 0.2099 1
Echinococcus granulosus vaccinia related kinase 1 0.0011 0.0005 0.0005
Brugia malayi serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi PRKD2 protein 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase 6 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis PAK box P21 Rho binding 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE7 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/DUAL protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0363 0.0363
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0054 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus nuclear receptor binding protein 0.0011 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Egg laying defective protein 4 0.0011 0.0005 0.0005
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0363 0.2099 1
Schistosoma mansoni kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis protein kinase c iota type 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus phd:f box containing protein 0.0019 0.0054 0.0054
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Echinococcus multilocularis cyclin dependent kinase 9 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.008 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Echinococcus granulosus serine:threonine protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0112 0.1338
Echinococcus granulosus casein kinase I alpha 0.0049 0.0235 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus STE20:SPS1 proline alanine rich protein 0.0011 0.0005 0.0005
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, putative 0.0049 0.0235 0.1098
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0011 0.0005 0.0005
Echinococcus granulosus rho-associated protein kinase 1 0.0175 0.0983 0.0983
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0011 0.0005 0.0005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.008 0.0358
Loa Loa (eye worm) TLK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1694 1 1
Echinococcus granulosus serine:threonine kinase SAD 1 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0037 0.0153
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus agc family protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.008 0.008
Brugia malayi MH2 domain containing protein 0.0144 0.0798 0.0798
Echinococcus multilocularis titin 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0011 0.0005 0.0005
Giardia lamblia Kinase, CMGC CDK 0.0363 0.2099 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, putative 0.0049 0.0235 0.1098
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0802 1
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Plasmodium vivax protein kinase Crk2 0.0363 0.2099 1
Brugia malayi Protein kinase domain 0.0011 0.0005 0.0005
Echinococcus multilocularis eukaryotic translation initiation factor 2 alpha 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0802 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0112 0.2865
Brugia malayi Serine/threonine-protein kinase Nek7 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Thioredoxin reductase 0.0057 0.0281 0.0281
Schistosoma mansoni P21-activated kinase pak 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0011 0.0005 0.0005
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0011 0.0005 0.0005
Brugia malayi casein kinase 1, delta 0.0049 0.0235 0.0235
Trypanosoma cruzi cdc2-related kinase 3 0.0363 0.2099 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0112 0.1338
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0112 0.0112
Loa Loa (eye worm) protein kinase domain-containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/TRBL protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AUR protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi casein kinase, putative 0.0049 0.0235 0.1098
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0124 0.068 0.068
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0148 0.0148
Echinococcus granulosus glycogen synthase kinase 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.008 0.0941
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0069 0.0799
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 1 0.0363 0.2099 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus twitchin 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase greatwall 0.0011 0.0005 0.0005
Echinococcus multilocularis protein kinase, core 0.0011 0.0005 0.0005
Echinococcus multilocularis beta adrenergic receptor kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis AP2 associated protein kinase 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0011 0.0005 0.0005
Brugia malayi serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus dna polymerase kappa 0.0023 0.008 0.008
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0011 0.0005 0.0005
Echinococcus granulosus Protein kinase C brain isozyme 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus aurora kinase A 0.0011 0.0005 0.0005
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase PAK 7 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 17 0.0011 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0363 0.2099 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0011 0.0005 0.0005
Echinococcus multilocularis wee1 protein kinase 0.0011 0.0005 0.0005
Brugia malayi TM2 domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0011 0.0005 0.0005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0377 0.1777
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0281 0.0281
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase ULK4 0.0011 0.0005 0.0005
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.2875 0.2875
Echinococcus granulosus serine/threonine-protein kinase greatwall 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase ULK3 0.0011 0.0005 0.0005
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0281 0.1317
Echinococcus granulosus death associated protein kinase 1 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 11 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 6 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis Serine:threonine protein kinase PINK1 0.0011 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Brugia malayi Protein kinase domain containing protein 0.0523 0.3048 0.3048
Echinococcus granulosus myosin light chain kinase smooth muscle 0.0011 0.0005 0.0005
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0054 0.0054
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase K06H7.1 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 1 0.0011 0.0005 0.0005
Echinococcus multilocularis protein kinase shaggy 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni dual specificity kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0112 0.0509
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0016 0.0037 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus TBC domain containing protein kinase 0.0011 0.0005 0.0005
Brugia malayi oxidative-stress responsive 1 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0235 0.0235
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Lyn 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) SCY1 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) NAK/MPSK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.2099 0.2099
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0377 0.1777
Echinococcus granulosus casein kinase I delta 0.0049 0.0235 0.0235
Echinococcus granulosus wee1 protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 38 0.0011 0.0005 0.0005
Trichomonas vaginalis CK1 family protein kinase 0.0049 0.0235 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0028 0.0028
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.0011 0.0005 0.0005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0059 0.0059
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0019 0.0054 0.0054
Loa Loa (eye worm) ULK/ULK protein kinase 0.0011 0.0005 0.0005
Giardia lamblia Kinase, PLK 0.0124 0.068 0.3225
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.008 0.0358
Echinococcus multilocularis cyclin dependent kinase 9 0.0011 0.0005 0.0005
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity serine:threonine tyrosine 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase WNK1 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis casein kinase I alpha 0.0049 0.0235 0.0235
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0011 0.0005 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0059 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0124 0.068 0.3225
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1694 1 1
Brugia malayi cell division control protein 2 homolog 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKA protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus c-Jun N-terminal kinases 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0124 0.068 0.068
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0802 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0715 0.8916
Brugia malayi phosphoinositide-dependent protein kinase I 0.0011 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.0057 0.0281 0.1317
Mycobacterium ulcerans hypothetical protein 0.0029 0.0112 0.2865
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0069
Loa Loa (eye worm) CK1 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0062 0.0712
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine/threonine-protein kinase greatwall 0.0011 0.0005 0.0005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0054 0.0054
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0049 0.0235 0.0235
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0363 0.2099 0.2099
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0363 0.0363
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0375 0.0375
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0094 0.0502 0.2372
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0112
Plasmodium falciparum thioredoxin reductase 0.002 0.0059 0.0258
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus cyclin g associated kinase 0.0011 0.0005 0.0005
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0054 0.0054
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0011 0.0005 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0028 0.0028
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus myosin iiia 0.0011 0.0005 0.0005
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0011 0.0005 0.0005
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity mitogen activated protein 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Brugia malayi Cytochrome P450 family protein 0.0032 0.0129 0.0129
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0049 0.0235 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/PSK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0011 0.0005 0.0005
Echinococcus multilocularis agc family protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis scy1 protein 2 0.0011 0.0005 0.0005
Echinococcus granulosus calcium activated potassium channel 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Onchocerca volvulus 0.0035 0.0148 0.1457
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/PKA protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0011 0.0005 0.0005
Echinococcus granulosus activin receptor type 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE7/MEK4 protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0059 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0011 0.0005 0.0005
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0059 0.0258
Brugia malayi p70 ribosomal S6 kinase beta 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine kinase 0.0011 0.0005 0.0005
Plasmodium vivax JmjC domain containing protein 0.0019 0.0054 0.0234
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis activin receptor type 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0011 0.0005 0.0005
Giardia lamblia DINP protein human, muc B family 0.0023 0.008 0.0358
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus protein KINase family member kin 1 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis dual specificity 0.0011 0.0005 0.0005
Echinococcus multilocularis twitchin 0.0011 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.008 0.0358
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.068 0.068
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.008 0.0941
Brugia malayi CXXC zinc finger family protein 0.0035 0.0148 0.0148
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0011 0.0005 0.0005
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0054 0.0234
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 6 0.0011 0.0005 0.0005
Echinococcus granulosus serine threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase ULK2 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0011 0.0005 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0059 0.0258
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0715 0.8916
Toxoplasma gondii thioredoxin reductase 0.0057 0.0281 0.1317
Loa Loa (eye worm) CMGC/CDK protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) haspin protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus protein kinase core 0.0011 0.0005 0.0005
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.4891 0.4891
Loa Loa (eye worm) BUB protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0363 0.2099 0.2099
Echinococcus multilocularis aurora kinase A 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.0011 0.0005 0.0005
Schistosoma mansoni kinase 0.0068 0.0347 0.0347
Brugia malayi probable protein kinase 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0011 0.0005 0.0005
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis expressed protein 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni DNA polymerase eta 0.0023 0.008 0.008
Echinococcus granulosus casein kinase I alpha 0.0049 0.0235 0.0235
Loa Loa (eye worm) plk/plk-unclassified protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis tau tubulin kinase 1 0.0011 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0112 0.0112
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Plasmodium vivax casein kinase 1, putative 0.0049 0.0235 0.1098
Loa Loa (eye worm) TKL/IRAK protein kinase 0.0011 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.008 0.0358
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0059 0.0258
Brugia malayi Serine/threonine-protein kinase SULU 0.0011 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 16 0.0011 0.0005 0.0005
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0011 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0011 0.0005 0.0005
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0363 0.2099 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0011 0.0005 0.0005
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0059 0.0258
Echinococcus granulosus Serine:threonine protein kinase PINK1 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0011 0.0005 0.0005
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0011 0.0005 0.0005
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.1694 1 1
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus 5'partial|3'partial|mitogen activated protein kinase kinase kinase 0.0011 0.0005 0.0005
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0069 0.0304
Echinococcus multilocularis myosin iiia 0.0011 0.0005 0.0005
Echinococcus granulosus serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 14 0.0011 0.0005 0.0005
Treponema pallidum NADH oxidase 0.002 0.0059 0.5
Brugia malayi Dual specificity mitogen-activated protein kinase kinase 7. -TRUNCATED- 0.0011 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0011 0.0005 0.0005
Echinococcus granulosus Serine:threonine protein kinase PFTAIRE 1 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0011 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0071 0.0363 0.0363
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0011 0.0005 0.0005
Echinococcus multilocularis ribosomal protein S6 kinase delta 1 0.0011 0.0005 0.0005
Loa Loa (eye worm) NAK/BIKE protein kinase 0.0011 0.0005 0.0005
Echinococcus granulosus agc family protein kinase 0.0011 0.0005 0.0005
Brugia malayi cell division control protein 2 homolog 0.0363 0.2099 0.2099
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0039 0.0172 0.0795

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 7.079457844 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 12.58925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 2.3778 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 7.9433 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 16.9441 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 67.4555 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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