Detailed information for compound 1584598

Basic information

Technical information
  • TDR Targets ID: 1584598
  • Name: ZINC03244076
  • MW: 391.443 | Formula: C21H17N3O3S
  • H donors: 0 H acceptors: 4 LogP: 2.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CCCN(C(=O)CN1c2cccc3c2c(S1(=O)=O)ccc3)c1ccccc1
  • InChi: 1S/C21H17N3O3S/c22-13-6-14-23(17-9-2-1-3-10-17)20(25)15-24-18-11-4-7-16-8-5-12-19(21(16)18)28(24,26)27/h1-5,7-12H,6,14-15H2
  • InChiKey: JRCWULXAIYBKOU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • T0511-4344
  • Oprea1_455542

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) beta-lactamase 0.0564 0.1526 0.3425
Echinococcus granulosus importin 5 0.0029 0.0034 0.0058
Schistosoma mansoni nuclear hormone receptor 0.006 0.012 0.0204
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0028 0.0033 0.0073
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0054 0.0156
Brugia malayi acetyltransferase, GNAT family protein 0.0302 0.0796 0.2185
Loa Loa (eye worm) hypothetical protein 0.0079 0.0174 0.039
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.0246 0.1612
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0162 0.0836
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0139 0.0343 0.0769
Toxoplasma gondii hypothetical protein 0.0031 0.004 0.025
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0028 0.0033 0.0073
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0074 0.0203
Trichomonas vaginalis beta-mannosidase, putative 0.0235 0.0609 0.3086
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0282 0.0769
Schistosoma mansoni cation-transporting ATPase 0.0017 0.0002 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0274 0.0717 0.1219
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0055 0.035
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.0079 0.0213
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.001 0.0054
Schistosoma mansoni pyruvate kinase 0.0036 0.0054 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0115 0.0275 0.0812
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0054 0.0122
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0115 0.0275 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.009 0.0204 0.0601
Schistosoma mansoni survival motor neuron protein 0.0096 0.0221 0.0376
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0021
Brugia malayi steroid hormone receptor 0.0126 0.0306 0.084
Schistosoma mansoni hypothetical protein 0.0043 0.0075 0.0127
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.006 0.012 0.033
Echinococcus multilocularis lamin 0.008 0.0178 0.0194
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0006 0.0036
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0296 0.0778 0.2337
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0059 0.0172
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 0.0552
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0084
Echinococcus granulosus high affinity choline transporter 1 0.0189 0.0481 0.0819
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.018 0.0456 0.0776
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0009 0.0046
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0005 0.0025
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0264 0.0287
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1209 0.3324 1
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0028 0.0033 0.0035
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.023 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Mycobacterium tuberculosis Conserved protein 0.0564 0.1526 0.1525
Trypanosoma brucei polo-like protein kinase 0.0105 0.0246 0.1603
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0002 0.0003
Brugia malayi MH2 domain containing protein 0.0368 0.0979 0.2686
Onchocerca volvulus 0.0149 0.037 0.2425
Echinococcus granulosus transportin 1 0.0029 0.0034 0.0058
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0055 0.0279
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0049 0.0135
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0264 0.0449
Trypanosoma cruzi hypothetical protein, conserved 0.0564 0.1526 0.4529
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.0079 0.0509
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0032 0.016
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0028 0.0033 0.0165
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.022 0.0566 0.0617
Giardia lamblia hypothetical protein 0.0028 0.0033 0.0905
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0135
Echinococcus granulosus bloom syndrome protein 0.0049 0.009 0.0153
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0044 0.0129
Trypanosoma brucei RNA editing exonuclease 2 0.0028 0.0033 0.0202
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0329 0.087 0.0869
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0.0002 0.0005
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0034 0.005 0.0314
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Echinococcus granulosus synaptojanin 1 0.0028 0.0033 0.0055
Leishmania major hypothetical protein, conserved 0.0564 0.1526 0.459
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0296 0.0778 0.0777
Mycobacterium tuberculosis Probable lipase LipD 0.0564 0.1526 0.1525
Brugia malayi Beta-glucuronidase precursor 0.0671 0.1825 0.5007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0099
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0225 0.0582 0.1305
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0028 0.0033 0.0165
Brugia malayi hypothetical protein 0.0712 0.1938 0.5317
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0139 0.0343 0.2237
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0059 0.0376
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.1615 0.4457 0.7579
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0034 0.0211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0275 0.0273
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0264 0.1337
Loa Loa (eye worm) hypothetical protein 0.0122 0.0293 0.0658
Brugia malayi MH2 domain containing protein 0.0025 0.0024 0.0066
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0002 0.0009
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0049 0.0141
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0079 0.0173 0.0389
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Echinococcus granulosus cation transporting ATPase 13A1 0.0017 0.0002 0.0003
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Brugia malayi Sugar transporter family protein 0.0108 0.0254 0.0697
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0122 0.0357
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0002 0.0009
Leishmania major endonuclease/exonuclease protein-like protein 0.0028 0.0033 0.0093
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0149 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0379 0.1011 0.5124
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0264 0.1719
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0025
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0006 0.0029
Echinococcus multilocularis pyruvate kinase 0.0028 0.0033 0.0036
Echinococcus granulosus lysine specific demethylase 5A 0.0083 0.0185 0.0314
Loa Loa (eye worm) hypothetical protein 0.0032 0.0042 0.0095
Brugia malayi Nuclear hormone receptor E75 0.006 0.012 0.033
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0029 0.0082
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0042 0.0266
Toxoplasma gondii ABC1 family protein 0.0564 0.1526 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0173 0.0509
Plasmodium vivax glutathione reductase, putative 0.013 0.0315 0.2057
Treponema pallidum exodeoxyribonuclease (exoA) 0.0139 0.0343 1
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0028 0.0033 0.0202
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0189 0.0481 0.0524
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0032 0.009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0213
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0006 0.0029
Chlamydia trachomatis pyruvate kinase 0.0036 0.0054 0.2609
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0185 0.0314
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0118 0.0282 0.028
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.0079 0.0509
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0033 0.0056
Echinococcus granulosus thioredoxin glutathione reductase 0.0131 0.0318 0.0541
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0021 0.0053
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0241 0.0627 0.0683
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Mycobacterium tuberculosis Conserved protein 0.0564 0.1526 0.1525
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0028 0.0033 0.0168
Echinococcus multilocularis bloom syndrome protein 0.0049 0.009 0.0098
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.002 0.0018
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0028 0.0033 0.0055
Mycobacterium ulcerans thioesterase 0.002 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0089 0.0202 0.1312
Trichomonas vaginalis D-aminoacylase, putative 0.0564 0.1526 0.7737
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0093 0.0158
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0033 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0126 0.0306 0.0333
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0021
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0108 0.0184
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.012 0.0131
Loa Loa (eye worm) nuclear hormone receptor 0.006 0.012 0.027
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0089 0.0201
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0074 0.016 0.0273
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0024 0.0041
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0052 0.0264
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0029 0.0032
Schistosoma mansoni alpha-glucosidase 0.0289 0.0761 0.1293
Onchocerca volvulus Glucosylceramidase homolog 0.036 0.0957 0.6269
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0028 0.0033 0.0073
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0003 0.0012
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0118 0.0282 0.028
Schistosoma mansoni synaptojanin 0.0028 0.0033 0.0055
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.005 0.0314
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0126 0.0306 0.0687
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0073
Plasmodium falciparum calcium-dependent protein kinase 3 0.0034 0.005 0.039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0009 0.0021
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0264 0.0789
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0032 0.0089
Schistosoma mansoni phd/f-box containing protein 0.002 0.0009 0.0016
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0055 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0126 0.0306 0.084
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.0168
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0049 0.0054
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0024 0.0054
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0047 0.0239
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0241 0.0627 0.172
Onchocerca volvulus 0.0126 0.0306 0.2005
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0044 0.0121
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0047 0.0298
Brugia malayi PHD-finger family protein 0.0061 0.0125 0.0343
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0274 0.0717 0.1967
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0139 0.0343 0.0341
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0054 0.0344
Echinococcus multilocularis pyruvate kinase 0.0036 0.0054 0.0059
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0074 0.0166
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0042 0.0116
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0079 0.023
Onchocerca volvulus 0.0564 0.1526 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.0189 0.0481 0.0819
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0028 0.0033 0.0251
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.006 0.012 0.0131
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.0139
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0122 0.0334
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0201 0.0514 0.0559
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0126 0.0306 0.0521
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0034 0.005 0.0111
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0054 0.0344
Toxoplasma gondii propionate-CoA ligase 0.0115 0.0275 0.1792
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0049 0.0141
Brugia malayi mbt repeat family protein 0.0049 0.0089 0.0246
Brugia malayi Latrophilin receptor protein 2 0.0274 0.0717 0.1967
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0865 0.2365 0.5307
Onchocerca volvulus 0.0043 0.0075 0.049
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0139 0.0343 0.0373
Schistosoma mansoni polycystin 1-related 0.0043 0.0075 0.0127
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0049 0.0048
Schistosoma mansoni hypothetical protein 0.0108 0.0254 0.0432
Brugia malayi Inositol-1 0.0036 0.0055 0.0151
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0162 0.0821
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0026 0.0074
Trichomonas vaginalis hypothetical protein 0.0029 0.0034 0.0172
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0456 0.1248
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0024 0.0041
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 1
Mycobacterium tuberculosis Probable lipase LipE 0.0564 0.1526 0.1525
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0059 0.0376
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0241 0.0627 0.1066
Leishmania major protein kinase, putative 0.0034 0.005 0.0144
Mycobacterium ulcerans beta-lactamase 0.0564 0.1526 0.4185
Echinococcus granulosus endonuclease exonuclease phosphatase 0.022 0.0566 0.0963
Trypanosoma brucei importin beta-1 subunit, putative 0.0151 0.0376 0.2454
Plasmodium falciparum calcium-dependent protein kinase 1 0.0034 0.005 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0054 0.0156
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0055 0.006
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0125 0.0808
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.0168
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0021 0.0036
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0024 0.0054
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0241 0.0627 0.0625
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0118 0.0282 0.0773
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0292 0.0318
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0564 0.1526 0.2596
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0241 0.0627 0.1882
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0126 0.0306 0.0687
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Plasmodium vivax thioredoxin reductase, putative 0.013 0.0315 0.2057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0712 0.1938 0.2111
Loa Loa (eye worm) transcription factor SMAD2 0.0368 0.0979 0.2197
Trypanosoma brucei protein kinase, putative 0.0111 0.0264 0.1719
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.006 0.012 0.0131
Entamoeba histolytica hypothetical protein 0.0024 0.0021 0.0109
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0055 0.0094
Schistosoma mansoni glucose transport protein 0.0108 0.0254 0.0432
Onchocerca volvulus Putative neutral sphingomyelinase 0.0028 0.0033 0.0213
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0054 0.0355
Trichomonas vaginalis set domain proteins, putative 0.0246 0.064 0.3245
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0009 0.0022
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0202
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0075 0.0594
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0009 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.007 0.0447
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0017 0.0002 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.018 0.0456 0.0497
Toxoplasma gondii facilitative glucose transporter GT1 0.0108 0.0254 0.1655
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0011 0.0009
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Trypanosoma cruzi importin beta-1 subunit, putative 0.0123 0.0296 0.0874
Brugia malayi AF-10 protein 0.002 0.001 0.0027
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0548 0.1483 0.4068
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0005 0.0031
Plasmodium falciparum hexose transporter 0.0108 0.0254 0.2053
Brugia malayi nuclear hormone receptor 0.0126 0.0306 0.084
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0075 0.0127
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0009 0.0015
Leishmania major importin beta-1 subunit, putative 0.0123 0.0296 0.0886
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0126 0.0306 0.0333
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0139 0.0343 0.1769
Loa Loa (eye worm) hypothetical protein 0.0074 0.016 0.036
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0022 0.002
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0009
Schistosoma mansoni protein kinase 0.0034 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0055 0.0108 0.0243
Trichomonas vaginalis importin beta-1, putative 0.0123 0.0296 0.1501
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0131 0.0222
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0032 0.016
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0125 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Onchocerca volvulus Huntingtin homolog 0.0122 0.0293 0.192
Brugia malayi manba-prov protein 0.0235 0.0609 0.167
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.0079 0.0509
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.0079 0.0402
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0122 0.0629
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0032 0.0206
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0089 0.0202 0.1312
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0162 0.0176
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0131 0.0142
Plasmodium falciparum calcium-dependent protein kinase 2 0.0034 0.005 0.039
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0047 0.0239
Leishmania major hypothetical protein, conserved 0.0028 0.0033 0.0093
Mycobacterium ulcerans short-chain dehydrogenase 0.0018 0.0004 0.0005
Echinococcus multilocularis synaptojanin 1 0.0028 0.0033 0.0035
Echinococcus multilocularis RUN 0.0043 0.0075 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.005 0.0251
Brugia malayi Cytochrome P450 family protein 0.0019 0.0007 0.0018
Trypanosoma brucei unspecified product 0.0042 0.007 0.0447
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0029 0.0034 0.0211
Leishmania major DNA polymerase kappa, putative 0.006 0.0122 0.0362
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0469 0.1263 0.2833
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0122 0.0207
Loa Loa (eye worm) inositol-1 0.0036 0.0055 0.0123
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0028 0.0033 0.0092
Trichomonas vaginalis helicase, putative 0.0034 0.0048 0.0245
Brugia malayi AMP-binding enzyme family protein 0.1324 0.3645 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0122 0.0357
Trichomonas vaginalis esterase, putative 0.0564 0.1526 0.7737
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0059 0.017
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0009 0.0015
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0009 0.0046
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0034 0.005 0.0136
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0052 0.0269
Toxoplasma gondii histone lysine methyltransferase SET1 0.0291 0.0766 0.5013
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0021 0.0157
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0032 0.016
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0047
Onchocerca volvulus 0.0115 0.0275 0.1801
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0032 0.016
Schistosoma mansoni synaptojanin 0.0028 0.0033 0.0055
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0115 0.0275 0.0823
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0009 0.0024
Schistosoma mansoni hypothetical protein 0.0323 0.0856 0.1455
Echinococcus granulosus dna polymerase eta 0.006 0.0122 0.0207
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0432
Trypanosoma brucei importin beta-1 subunit, putative 0.0151 0.0376 0.2454
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0026 0.0067
Schistosoma mansoni hypothetical protein 0.0712 0.1938 0.3296
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0221 0.0606
Loa Loa (eye worm) oxidoreductase 0.0115 0.0275 0.0617
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0115 0.0275 0.1792
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0122 0.0207
Loa Loa (eye worm) hypothetical protein 0.0178 0.0451 0.1011
Echinococcus granulosus RUN 0.0043 0.0075 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0033 0.0202
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0.0002 0.0005
Echinococcus granulosus neuropeptide s receptor 0.0922 0.2524 0.4292
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0115 0.0275 0.0812
Schistosoma mansoni nuclear receptor 0.006 0.012 0.0204
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1324 0.3645 1
Schistosoma mansoni ets-related 0.0212 0.0546 0.0929
Loa Loa (eye worm) hypothetical protein 0.0436 0.117 0.2626
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0054
Brugia malayi MH1 domain containing protein 0.0025 0.0024 0.0066
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0034 0.005 0.0111
Trypanosoma brucei trypanothione reductase 0.013 0.0315 0.2057
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0054 0.0149
Leishmania major RNA-editing complex protein MP100, putative 0.0028 0.0033 0.0093
Loa Loa (eye worm) hypothetical protein 0.0178 0.0451 0.1011
Loa Loa (eye worm) MH2 domain-containing protein 0.0368 0.0979 0.2197
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.013 0.0315 0.0314
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.0116 0.0198
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0456 0.1248
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0032 0.016
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0115 0.0275 0.075
Schistosoma mansoni lamin 0.008 0.0178 0.0303
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0047 0.0239
Brugia malayi hypothetical protein 0.0043 0.0075 0.0205
Schistosoma mansoni acetyl-CoA synthetase 0.0115 0.0275 0.0468
Loa Loa (eye worm) jmjC domain-containing protein 0.0083 0.0185 0.0414
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0024 0.0022 0.0061
Mycobacterium ulcerans polyketide synthase 0.0024 0.0022 0.0056
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0122 0.0788
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0021 0.0057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.012 0.0131
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0173 0.1395
Loa Loa (eye worm) hypothetical protein 0.0591 0.1602 0.3595
Echinococcus granulosus smad 0.0025 0.0024 0.0041
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0028 0.0033 0.0073
Echinococcus multilocularis translational activator gcn1 0.0029 0.0034 0.0037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.012 0.0204
Brugia malayi AMP-binding enzyme family protein 0.0115 0.0275 0.0754
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0123 0.0296 0.1501
Onchocerca volvulus 0.008 0.0178 0.1165
Echinococcus multilocularis nuclear receptor nhr 48 0.006 0.012 0.0131
Brugia malayi Smad1 0.0025 0.0024 0.0066
Brugia malayi Cam kinase protein 1 0.0034 0.005 0.0136
Mycobacterium ulcerans lipase LipD 0.0564 0.1526 0.4185
Loa Loa (eye worm) hypothetical protein 0.0865 0.2365 0.5307
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0122 0.0618
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0089 0.0152
Giardia lamblia PHD finger protein 15 0.0061 0.0125 0.3612
Plasmodium vivax hypothetical protein, conserved 0.0564 0.1526 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0024 0.0022 0.006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0123 0.0296 0.1501
Schistosoma mansoni inositol monophosphatase 0.0036 0.0055 0.0094
Brugia malayi Cytochrome P450 family protein 0.0019 0.0007 0.0018
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0009 0.0049
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0189 0.0481 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus granulosus pyruvate kinase 0.0036 0.0054 0.0092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0115 0.0275 0.1419
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0017 0.0002 0.0003
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0017 0.0002 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0131 0.0222
Echinococcus multilocularis neuropeptide receptor A26 0.0922 0.2524 0.2749
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Loa Loa (eye worm) Smad1 0.0025 0.0024 0.0054
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0009 0.0021
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.0253
Schistosoma mansoni zinc finger protein 0.006 0.012 0.0204
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0009 0.0046
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0028 0.0033 0.0202
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0318 0.084 0.1428
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.012 0.0131
Leishmania major pantothenate kinase subunit, putative 0.0044 0.0077 0.0227
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0059 0.0376
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0009 0.0016
Leishmania major glucose transporter, lmgt2 0.0033 0.0047 0.0137
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0021 0.0107
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0049 0.0084
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0009 0.0061
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0131 0.0222
Echinococcus granulosus phd:f box containing protein 0.002 0.0009 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0264 0.1719
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0564 0.1526 0.4188
Brugia malayi jmjC domain containing protein 0.0083 0.0185 0.0506
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0126 0.0306 0.0521
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0139 0.0343 0.1013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0073
Trichomonas vaginalis penicillin-binding protein, putative 0.0564 0.1526 0.7737
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0173 0.1124
Brugia malayi Calcitonin receptor-like protein seb-1 0.0865 0.2365 0.6488
Schistosoma mansoni lipoxygenase 0.0121 0.0292 0.0497
Loa Loa (eye worm) hypothetical protein 0.0105 0.0247 0.0554
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0009 0.001
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0017 0.0002 0.0002
Echinococcus granulosus intermediate filament protein 0.008 0.0178 0.0303
Onchocerca volvulus 0.0096 0.0221 0.1448
Leishmania major acetyl-CoA synthetase, putative 0.0115 0.0275 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Leishmania major DNA polymerase eta, putative 0.0019 0.0006 0.0013
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0009 0.001
Loa Loa (eye worm) histone methyltransferase 0.0047 0.0086 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0126 0.0306 0.084
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0092
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0162 0.0821
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0126 0.0306 0.084
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0189 0.0481 0.0524
Schistosoma mansoni sodium/solute symporter 0.0189 0.0481 0.0819
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0044 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0162 0.0476
Echinococcus multilocularis geminin 0.1938 0.5356 0.5834
Brugia malayi hypothetical protein 0.0122 0.0293 0.0804
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0192 0.0326
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.0809 0.5293
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.007 0.0447
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Mycobacterium tuberculosis Probable oxidoreductase 0.0329 0.087 0.0869
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0042 0.0046
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0032 0.0195
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0009 0.001
Schistosoma mansoni lipoxygenase 0.0043 0.0075 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Mycobacterium ulcerans glutaminase 0.0546 0.1477 0.4049
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0026 0.0025
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0139 0.0343 0.1027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0028 0.0033 0.0092
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Loa Loa (eye worm) hypothetical protein 0.0189 0.0481 0.108
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0009
Loa Loa (eye worm) DR-78 0.006 0.012 0.027
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0028 0.0033 0.0251
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0009 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.0079 0.0631
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Echinococcus granulosus cation transporting atpase worm 0.0017 0.0002 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0712 0.1938 0.3296
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0264 0.0287
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0032 0.0163
Plasmodium falciparum thioredoxin reductase 0.0045 0.0079 0.0631
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0009 0.0016
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0302 0.0796 0.1354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0029 0.0148
Schistosoma mansoni protein kinase 0.0034 0.005 0.0084
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0011 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0246 0.0419
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.0079 0.0402
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0115 0.0275 0.1792
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0175 0.0442 0.2891
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0045 0.008 0.0636
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0017 0.0002 0.0004
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0028 0.0033 0.0092
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0052 0.015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0126 0.0306 0.0687
Toxoplasma gondii exonuclease III APE 0.0139 0.0343 0.2237
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0264 0.1337
Loa Loa (eye worm) hypothetical protein 0.0189 0.0481 0.108
Loa Loa (eye worm) MBCTL1 0.0055 0.0108 0.0243
Schistosoma mansoni pyruvate kinase 0.0036 0.0054 0.0092
Mycobacterium tuberculosis Probable dehydrogenase 0.0296 0.0778 0.0777
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0006 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0049 0.0054
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0033 0.0205
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0017 0.0002 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0239
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0162 0.0444
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 1
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.014 0.0384
Brugia malayi MAP kinase sur-1 0.0111 0.0264 0.0724
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0865 0.2365 0.6488
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0029 0.018
Loa Loa (eye worm) importin-beta domain-containing protein 0.0029 0.0034 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0018 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0074 0.0215
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0074 0.0476
Brugia malayi AMP-binding enzyme family protein 0.0023 0.002 0.0054
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0189 0.0481 0.3145
Echinococcus multilocularis Smad4 0.0025 0.0024 0.0026
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.0079 0.3854
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Brugia malayi GH02984p 0.0189 0.0481 0.1321
Trypanosoma cruzi hexose transporter 0.0033 0.0047 0.0135
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.331 0.9181 1
Brugia malayi nuclear receptor NHR-88 0.0126 0.0306 0.084
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0089 0.0203 0.132
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0162 0.0482
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.0079 0.0631
Echinococcus granulosus peregrin 0.0069 0.0146 0.0248
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0089 0.0152
Loa Loa (eye worm) E1-E2 ATPase 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0042
Onchocerca volvulus Protein ultraspiracle homolog 0.0126 0.0306 0.2005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0017 0.0029
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.0456 0.0776
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0092
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0009 0.0021
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0028 0.0033 0.0202
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.0061 0.0125 0.0212
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0175 0.0442 0.2891
Echinococcus multilocularis AMP dependent ligase 0.0018 0.0006 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0564 0.1526 0.1663
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0809 0.2397
Schistosoma mansoni smad1 5 8 and 0.0025 0.0024 0.0041
Toxoplasma gondii type I fatty acid synthase, putative 0.0042 0.0071 0.0453
Schistosoma mansoni inositol transporter 0.0189 0.0481 0.0819
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0059 0.0172
Echinococcus granulosus cpg binding protein 0.0158 0.0394 0.067
Loa Loa (eye worm) calcium ATPase 0.0017 0.0002 0.0004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0067 0.014 0.0238
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0118 0.0282 0.028
Toxoplasma gondii type I fatty acid synthase, putative 0.0017 0.0002 0.0005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0201 0.0514 0.0874
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.014 0.0384
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0383 0.1023 0.1114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0383 0.1023 0.174
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0115 0.0275 0.075
Trichomonas vaginalis hypothetical protein 0.0018 0.0005 0.0024
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1324 0.3645 0.8179
Trichomonas vaginalis conserved hypothetical protein 0.0724 0.1973 1
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.013
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0122 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0126 0.0306 0.0333
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0122 0.0618
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0029 0.0035 0.0273
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.009 0.0204 0.1646
Brugia malayi nuclear hormone receptor 0.006 0.012 0.033
Loa Loa (eye worm) hypothetical protein 0.0156 0.0389 0.0872
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0306 0.0521
Giardia lamblia Kinase, PLK 0.0105 0.0246 0.7165
Onchocerca volvulus 0.0043 0.0075 0.049
Echinococcus granulosus importin subunit beta 1 0.0151 0.0376 0.0639
Schistosoma mansoni nocturnin 0.0028 0.0033 0.0055
Schistosoma mansoni steroid hormone receptor ad4bp 0.0126 0.0306 0.0521
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0017 0.0002 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0139 0.0343 0.0583
Mycobacterium leprae Probable lipase LipE 0.0564 0.1526 0.459
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0101 0.0294
Schistosoma mansoni jumonji domain containing protein 0.0159 0.0399 0.0678
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0067 0.014 0.0153
Leishmania major hypothetical protein, conserved 0.0028 0.0033 0.0093
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0054 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0048 0.0082
Brugia malayi beta-lactamase family protein 0.0564 0.1526 0.4188
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0002 0.0003
Onchocerca volvulus 0.0564 0.1526 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0564 0.1526 0.2596
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.0161 0.0175
Brugia malayi follicle stimulating hormone receptor 0.0694 0.1888 0.5181
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0086
Schistosoma mansoni alpha glucosidase 0.0075 0.0162 0.0275
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0002 0.0003
Trichomonas vaginalis Phospholipase C precursor, putative 0.0028 0.0033 0.0165
Brugia malayi Bloom's syndrome protein homolog 0.0049 0.009 0.0246
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0047 0.0086 0.0146
Trypanosoma brucei unspecified product 0.0042 0.007 0.0447
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.006 0.012 0.0204
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0131 0.0293
Leishmania major hypothetical protein, conserved 0.0029 0.0034 0.0097
Schistosoma mansoni protein phosphatase 2C 0.002 0.0009 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Brugia malayi Carboxylesterase family protein 0.0074 0.016 0.044
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0115 0.0275 0.0823
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0126 0.0306 0.0521
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Schistosoma mansoni copper ABC transporter ATPase 0.0017 0.0002 0.0003
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0062 0.0068
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0054 0.0355
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0404 0.0403
Onchocerca volvulus 0.0158 0.0393 0.2576
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0138 0.0338 0.0337
Brugia malayi RNA binding protein 0.0063 0.0131 0.0359
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.0079 0.2274
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0009 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0264 0.1337
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0264 0.0778
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0115 0.0275 0.0823
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0055 0.0146
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0509
Trypanosoma brucei glucose transporter 1E 0.0033 0.0047 0.0298
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0329 0.087 0.0869
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0089 0.0097
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0021 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.0254 0.1288
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.002 0.0011 0.0027
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0022 0.0056
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0192 0.0209
Entamoeba histolytica HEAT repeat domain containing protein 0.0029 0.0034 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0126 0.0306 0.084
Echinococcus granulosus thyroid hormone receptor alpha 0.006 0.012 0.0204
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Leishmania major glucose transporter, lmgt1 0.0033 0.0047 0.0137
Leishmania major 4-coumarate:coa ligase-like protein 0.0115 0.0275 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0564 0.1526 0.4185
Schistosoma mansoni aldehyde dehydrogenase 0.018 0.0456 0.0776
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0005 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0383 0.1023 0.174
Entamoeba histolytica hypothetical protein 0.0712 0.1938 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.009 0.0204 0.0347
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) glutaminase 2 0.0546 0.1477 0.3314
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0028 0.0033 0.0055
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0292 0.0497
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0075 0.0479
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0126 0.0306 0.0521
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0306 0.084
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0028 0.0033 0.0202
Brugia malayi hypothetical protein 0.0051 0.0096 0.0262
Loa Loa (eye worm) hypothetical protein 0.006 0.0122 0.0274
Trypanosoma cruzi mitochondrial protein 99, putative 0.0028 0.0033 0.0092
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0017 0.0002 0.0009
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0031 0.004 0.031
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Loa Loa (eye worm) hypothetical protein 0.0122 0.0293 0.0658
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0075 0.0081
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0275 0.0273
Onchocerca volvulus 0.0246 0.064 0.4194
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0018 0.0006 0.0011
Echinococcus multilocularis cpg binding protein 0.0158 0.0394 0.0429
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0007 0.0015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0891 0.097
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0809 0.2397
Schistosoma mansoni smad1 5 8 and 0.0025 0.0024 0.0041
Onchocerca volvulus 0.005 0.0093 0.0608
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0277
Echinococcus granulosus mixed lineage leukemia protein mll 0.0038 0.0061 0.0103
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0024 0.0022 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0049 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0032 0.016
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0383 0.1023 0.1114
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0115 0.0275 0.1792
Echinococcus granulosus tar DNA binding protein 0.0063 0.0131 0.0222
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0031 0.004 0.1118
Entamoeba histolytica acyl-coA synthetase, putative 0.0115 0.0275 0.1419
Echinococcus multilocularis transportin 1 0.0029 0.0034 0.0037
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.012 0.0787
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0329 0.087 0.2614
Plasmodium vivax CDK-related protein kinase 6, putative 0.0458 0.1231 0.8061
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0162 0.0821
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0026 0.0074
Mycobacterium ulcerans hypothetical protein 0.0564 0.1526 0.4185
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0307 0.0689
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0277
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0691 0.1879 0.5156
Schistosoma mansoni hypothetical protein 0.0274 0.0717 0.1219
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0122 0.0207
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Schistosoma mansoni nuclear hormone receptor 0.006 0.012 0.0204
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0089 0.0203 0.0345
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0125 0.0808
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0203 0.132
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0006 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0061 0.0103
Plasmodium falciparum protein kinase 7 0.0305 0.0805 0.6537
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Loa Loa (eye worm) carboxylesterase 0.0074 0.016 0.036
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0115 0.0275 0.03
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0034 0.005 0.0314
Schistosoma mansoni lamin 0.008 0.0178 0.0303
Echinococcus granulosus sodium:glucose cotransporter 0.0189 0.0481 0.0819
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0049 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0274 0.0717 0.0781
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0009 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0086 0.0194
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0115 0.0275 0.0812
Echinococcus multilocularis musashi 0.008 0.0178 0.0194
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0055 0.0284
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0162 0.0821
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0099
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0054 0.0275
Entamoeba histolytica hypothetical protein 0.0027 0.0029 0.0151
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0218
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0006 0.0029
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0139 0.0343 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0044 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0306 0.0333
Schistosoma mansoni myst-related protein 0.0018 0.0003 0.0005
Schistosoma mansoni inositol monophosphatase 0.0036 0.0055 0.0094
Loa Loa (eye worm) hypothetical protein 0.006 0.0121 0.0271
Echinococcus multilocularis dna polymerase kappa 0.006 0.0122 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Schistosoma mansoni ATPase 0.0017 0.0002 0.0003
Onchocerca volvulus 0.006 0.012 0.0787
Echinococcus granulosus dnaJ subfamily B 0.2126 0.588 1
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0118 0.0282 0.0769
Loa Loa (eye worm) hypothetical protein 0.0061 0.0125 0.028
Echinococcus multilocularis peptidase Clp (S14 family) 0.0059 0.0117 0.0128
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0122 0.0274
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Brugia malayi hypothetical protein 0.006 0.012 0.033
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0007 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.0246 0.0268
Mycobacterium ulcerans polyketide synthase 0.0026 0.0026 0.0067
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0089 0.0202 0.1023
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0055 0.0158
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0028 0.0033 0.0165
Brugia malayi hypothetical protein 0.0079 0.0173 0.0475
Schistosoma mansoni hypothetical protein 0.0254 0.0663 0.1128
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0203 0.132
Brugia malayi CCR4 0.0028 0.0033 0.0089
Schistosoma mansoni FFA transport protein 0.1225 0.3369 0.5729
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.0246 0.127
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0002 0.0009
Mycobacterium tuberculosis Probable reductase 0.0296 0.0778 0.0777
Echinococcus granulosus solute carrier family 5 0.0189 0.0481 0.0819
Leishmania major cytochrome p450-like protein 0.0019 0.0007 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0002 0.0005
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0108 0.0184
Echinococcus multilocularis acetylcholinesterase 0.0074 0.016 0.0175
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0126 0.0306 0.0521
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0089 0.0097
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0028 0.0033 0.0165
Brugia malayi orphan nuclear receptor NR2E1 0.006 0.012 0.033
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.0079 0.0213
Loa Loa (eye worm) hypothetical protein 0.0115 0.0275 0.0617
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0277
Brugia malayi photoreceptor-specific nuclear receptor 0.0126 0.0306 0.084
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0089 0.0203 0.0606
Entamoeba histolytica Ran family GTPase 0.009 0.0204 0.1053
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0009 0.0046
Onchocerca volvulus 0.0138 0.0338 0.2217
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0115 0.0275 0.075
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0115 0.0275 0.075
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.009 0.0455
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0149 0.0335
Brugia malayi MH1 domain containing protein 0.0025 0.0024 0.0066
Brugia malayi hypothetical protein 0.006 0.012 0.033
Loa Loa (eye worm) hypothetical protein 0.0049 0.0089 0.0201
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0118 0.0282 0.028
Loa Loa (eye worm) hypothetical protein 0.0115 0.0275 0.0617
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0021
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0115 0.0275 0.0823
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0306 0.084
Brugia malayi conserved hypotetical protein 0.006 0.012 0.033
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0021 0.0058
Schistosoma mansoni blooms syndrome DNA helicase 0.0033 0.0045 0.0076
Echinococcus granulosus General substrate transporter 0.0092 0.0212 0.036
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0006 0.0029
Mycobacterium tuberculosis Probable esterase LipL 0.0564 0.1526 0.1525
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0126 0.0306 0.0521
Echinococcus granulosus beta LACTamase domain containing family member 0.0564 0.1526 0.2596
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0125 0.0212
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0028 0.0033 0.0092
Brugia malayi hypothetical protein 0.0017 0.0002 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0246 0.0726
Onchocerca volvulus Alhambra homolog 0.0061 0.0125 0.0818
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0022 0.0056
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0028 0.0033 0.0035
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1225 0.3369 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0074 0.0215
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0189 0.0481 0.0819
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0092
Schistosoma mansoni jumonji domain containing protein 0.002 0.0009 0.0016
Brugia malayi tailless protein 0.006 0.012 0.033
Schistosoma mansoni ran 0.009 0.0204 0.0347
Loa Loa (eye worm) glutathione reductase 0.013 0.0315 0.0708
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0564 0.1526 0.1525
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0047 0.0298
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0002 0.0009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0079 0.0843
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0115 0.0275 0.0468
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0042 0.0072
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0013 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0162 0.0821
Brugia malayi Fli-1 protein 0.0212 0.0546 0.1498
Mycobacterium tuberculosis Conserved protein 0.0564 0.1526 0.1525
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0075 0.0081
Trypanosoma brucei hypothetical protein, conserved 0.0564 0.1526 1
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0028 0.0033 0.0165
Echinococcus granulosus lysosomal alpha glucosidase 0.0336 0.0891 0.1515
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0024 0.0026
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0017 0.0002 0.0004
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0264 0.0592
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0122 0.0788
Schistosoma mansoni glucose transport protein 0.0108 0.0254 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0185 0.0314
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0048 0.0082
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0108 0.0118
Echinococcus multilocularis cation transporting ATPase 13A1 0.0017 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0103 0.0522
Echinococcus granulosus snurportin 1 0.1615 0.4457 0.7579
Onchocerca volvulus 0.0115 0.0275 0.1801
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0126 0.0306 0.0687
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0432
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.018 0.0456 0.0455
Echinococcus multilocularis deoxyribonuclease 1 2 0.0028 0.0033 0.0035
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0138 0.0338 0.0759
Onchocerca volvulus 0.0564 0.1526 1
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Echinococcus granulosus neutral sphingomyelinase 0.0028 0.0033 0.0055
Toxoplasma gondii hypothetical protein 0.0049 0.0092 0.0592
Giardia lamblia Inositol 5-phosphatase 4 0.0028 0.0033 0.0905
Brugia malayi nuclear receptor RXR 0.006 0.012 0.033
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1225 0.3369 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0126 0.0306 0.0687
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0383 0.1023 0.174
Echinococcus granulosus cation transporting ATPase 13A3 0.0017 0.0002 0.0003
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0092
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0049 0.0312
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.006 0.012 0.0204
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0264 0.1337
Schistosoma mansoni kinase 0.0055 0.0107 0.0181
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0158 0.0394 0.067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0275 0.0273
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0007 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0002 0.0009
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0021 0.0023
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0564 0.1526 0.4185
Echinococcus multilocularis snurportin 1 0.1615 0.4457 0.4854
Onchocerca volvulus 0.0028 0.0033 0.0213
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0558 0.1252
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0007 0.0015
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0084
Loa Loa (eye worm) beta-glucuronidase 0.0671 0.1825 0.4095
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0032 0.0089
Echinococcus granulosus traf and tnf receptor associated protein 0.0028 0.0033 0.0055
Trypanosoma brucei unspecified product 0.006 0.0122 0.0788
Brugia malayi AMP-binding enzyme family protein 0.0115 0.0275 0.0754
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0034 0.005 0.0314
Loa Loa (eye worm) hypothetical protein 0.0067 0.014 0.0314
Echinococcus multilocularis thyroid hormone receptor alpha 0.0126 0.0306 0.0333
Loa Loa (eye worm) RNA binding protein 0.0063 0.0131 0.0293
Loa Loa (eye worm) hypothetical protein 0.005 0.0093 0.0208
Trichomonas vaginalis penicillin-binding protein, putative 0.0564 0.1526 0.7737
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.012 0.0787
Plasmodium vivax transportin, putative 0.0029 0.0034 0.0211
Mycobacterium ulcerans polyketide synthase Pks13 0.0036 0.0056 0.0148
Schistosoma mansoni high-affinity choline transporter 0.0189 0.0481 0.0819
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0047 0.0135
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0122 0.0334
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0009 0.0021
Loa Loa (eye worm) acetylcholinesterase 1 0.0074 0.016 0.036
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0009 0.0045
Echinococcus granulosus tumor protein p63 0.034 0.0902 0.1534
Loa Loa (eye worm) hypothetical protein 0.0034 0.005 0.0111
Echinococcus multilocularis GPCR, family 2 0.0274 0.0717 0.0781
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0026 0.0025
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Trichomonas vaginalis antibiotic synthetase, putative 0.0115 0.0275 0.1394
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.002 0.001 0.0008
Treponema pallidum NADH oxidase 0.0045 0.0079 0.2274
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0028 0.0033 0.0165
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0048 0.0082
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0021 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0275 0.0273
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.0246 0.0736
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0432
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0006 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0126 0.0306 0.0333
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0009 0.0021
Echinococcus multilocularis cation transporting atpase worm 0.0017 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.0079 0.0233
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0042 0.0266
Schistosoma mansoni peptidase Clp (S14 family) 0.0089 0.0203 0.0345
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0025
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0047 0.0239
Echinococcus multilocularis lamin dm0 0.008 0.0178 0.0194
Brugia malayi intermediate filament protein 0.008 0.0178 0.0488
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.0042 0.119
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0025
Trichomonas vaginalis antibiotic synthetase, putative 0.0115 0.0275 0.1394
Leishmania major hypothetical protein, conserved 0.0028 0.0033 0.0093
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0022 0.0056
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0047 0.0135
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0383 0.1023 0.2295
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0054 0.0275
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0359 0.234
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.009 0.0204 0.0601
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0047 0.0239
Brugia malayi CXXC zinc finger family protein 0.0149 0.037 0.1016
Plasmodium vivax exodeoxyribonuclease III, putative 0.0028 0.0033 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Schistosoma mansoni nuclear receptor nhr-48 0.006 0.012 0.0204
Toxoplasma gondii protein kinase, putative 0.0305 0.0805 0.527
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0029 0.018
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Loa Loa (eye worm) nuclear receptor nhr-7B 0.006 0.012 0.027
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0049 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0115 0.0275 0.0754
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0306 0.0521
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0028 0.0033 0.0165
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0302 0.0796 0.0867
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0062 0.0106
Brugia malayi TAR-binding protein 0.0063 0.0131 0.0359
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0202
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0021 0.0567
Plasmodium vivax acetyl-CoA synthetase, putative 0.0115 0.0275 0.1792
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0055 0.0279
Echinococcus granulosus histone acetyltransferase KAT2B 0.0089 0.0202 0.0343
Onchocerca volvulus 0.0034 0.0048 0.0318
Loa Loa (eye worm) glutaminase 0.0546 0.1477 0.3314
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0052 0.0331
Entamoeba histolytica hypothetical protein 0.0712 0.1938 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0264 0.0778
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0046 0.0083 0.0227
Schistosoma mansoni glucose transport protein 0.0108 0.0254 0.0432
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0264 0.0778
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.009 0.0204 0.5931
Brugia malayi Bromodomain containing protein 0.0069 0.0146 0.0399
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0564 0.1526 0.1525
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.001 0.0054
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Mycobacterium leprae conserved hypothetical protein 0.0564 0.1526 0.459
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0115 0.0275 0.1419
Schistosoma mansoni retinoic acid receptor RXR 0.0126 0.0306 0.0521
Onchocerca volvulus 0.0189 0.0481 0.3153
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0028 0.0033 0.0168
Leishmania major DNA damage repair protein, putative 0.0019 0.0006 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0564 0.1526 0.7737
Echinococcus granulosus AMP dependent ligase 0.0018 0.0006 0.0009
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0118 0.0282 0.0769
Plasmodium falciparum protein kinase 6 0.0458 0.1231 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.009 0.0204 0.056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0139 0.0343 0.1013
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0022 0.0056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0034 0.005 0.0084
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0021 0.0058
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0038 0.0061 0.0066
Entamoeba histolytica hypothetical protein 0.0712 0.1938 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.0246 0.0675
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.004 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0009 0.002
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.001 0.0054
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0036 0.0062
Trichomonas vaginalis D-aminoacylase, putative 0.0564 0.1526 0.7737
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0028 0.0033 0.0165
Leishmania major pyruvate kinase 0.0036 0.0054 0.0158
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0149 0.0162
Schistosoma mansoni rab6-interacting 0.0043 0.0075 0.0127
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0202
Echinococcus multilocularis copper transporting ATPase 1 0.0017 0.0002 0.0002
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0044 0.0223
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0067 0.014 0.0238
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0009 0.0049
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.001 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0139 0.0343 0.1738
Onchocerca volvulus 0.006 0.012 0.0787
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0018 0.0003 0.0001
Echinococcus multilocularis importin subunit beta 1 0.0151 0.0376 0.0409
Loa Loa (eye worm) hypothetical protein 0.0115 0.0275 0.0617
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0002 0.0002
Echinococcus granulosus carboxylesterase 5A 0.0074 0.016 0.0273
Trichomonas vaginalis ap endonuclease, putative 0.0139 0.0343 0.1738
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.012 0.0204
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0054 0.0158
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0162 0.0275
Brugia malayi PHD-finger family protein 0.0029 0.0034 0.0092
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0021 0.0127
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0009 0.0021
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0026 0.0074
Plasmodium vivax hypothetical protein, conserved 0.002 0.0009 0.0049
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.0233
Loa Loa (eye worm) intermediate filament protein 0.008 0.0178 0.0399
Plasmodium falciparum calcium-dependent protein kinase 4 0.0034 0.005 0.039
Treponema pallidum hypothetical protein 0.0028 0.0033 0.0905
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.005 0.0084
Schistosoma mansoni cript-related 0.0028 0.0033 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0103 0.0522
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0042 0.0116
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0004
Leishmania major trypanothione reductase 0.013 0.0315 0.0944
Plasmodium vivax hexose transporter 0.0108 0.0254 0.1655
Echinococcus granulosus translational activator gcn1 0.0029 0.0034 0.0058
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0009 0.0015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0122 0.0362
Schistosoma mansoni importin-beta 2 0.0029 0.0034 0.0058
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0061
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0037 0.0229
Mycobacterium tuberculosis Probable thioesterase TesA 0.002 0.0011 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0162 0.0476
Echinococcus multilocularis dnaJ subfamily B 0.2126 0.588 0.6404
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0122 0.0357
Schistosoma mansoni coup transcription factor 0.0126 0.0306 0.0521
Plasmodium falciparum transportin 0.0029 0.0034 0.0261
Brugia malayi nuclear receptor NHR-67 0.006 0.012 0.033
Schistosoma mansoni myst-related protein 0.0018 0.0003 0.0005
Onchocerca volvulus 0.008 0.0178 0.1165
Plasmodium falciparum calcium-dependent protein kinase 5 0.0034 0.005 0.039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0306 0.0521
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0891 0.097
Mycobacterium ulcerans hypothetical protein 0.0162 0.0404 0.1105
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0126 0.0306 0.0521
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0028 0.0033 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0115 0.0275 0.0823
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0054 0.0344
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0009 0.0045
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0044 0.0128
Echinococcus granulosus neuropeptide receptor A26 0.0922 0.2524 0.4292
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0049 0.0054
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0054 0.0053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Echinococcus granulosus pyruvate kinase 0.0036 0.0054 0.0092
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.009 0.0204 0.0458
Schistosoma mansoni hypothetical protein 0.0591 0.1602 0.2725
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Schistosoma mansoni DNA helicase recq5 0.0032 0.0042 0.0072
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0052 0.0089
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0044 0.0077 0.0224
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0336 0.0891 0.1999
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0122 0.0357
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0162 0.1051
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0115 0.0275 0.075
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0274 0.0717 0.1219
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0054 0.0344
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0021
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0359 0.1074
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.002 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0048 0.0053
Loa Loa (eye worm) kap beta 3 protein 0.0029 0.0034 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0306 0.0521
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0122 0.0357
Entamoeba histolytica beta-galactosidase, putative 0.0489 0.1318 0.6801
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0044 0.0075
Schistosoma mansoni loxhd1 0.0043 0.0075 0.0127
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0059 0.017
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0118 0.0282 0.0769
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0021 0.0036
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0115 0.0275 0.0273
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0115 0.0275 0.075
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0017 0.0002 0.0003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.0246 0.0552
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0021 0.0127
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0564 0.1526 0.3425
Loa Loa (eye worm) hypothetical protein 0.0074 0.016 0.036
Trypanosoma cruzi trypanothione reductase, putative 0.013 0.0315 0.0932
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0059 0.0117 0.0116
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0029 0.008
Plasmodium falciparum glutathione reductase 0.013 0.0315 0.2552
Trypanosoma brucei glucosidase, putative 0.0075 0.0162 0.1051
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0017 0.0002 0.0009
Schistosoma mansoni hypothetical protein 0.0274 0.0717 0.1219
Trypanosoma cruzi hypothetical protein, conserved 0.0564 0.1526 0.4529
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0028 0.0033 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0048 0.0082
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0115 0.0275 0.0273
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Loa Loa (eye worm) acetyltransferase 0.0302 0.0796 0.1787
Giardia lamblia GTOR 0.002 0.0009 0.0206
Onchocerca volvulus 0.0134 0.0327 0.2143
Brugia malayi nuclear hormone receptor family member nhr-6 0.006 0.012 0.033
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.0079 0.0135
Loa Loa (eye worm) hypothetical protein 0.008 0.0178 0.0399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Loa Loa (eye worm) hypothetical protein 0.0564 0.1526 0.3425
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.012 0.0204
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0034 0.0211
Schistosoma mansoni beta-mannosidase 0.0235 0.0609 0.1035
Echinococcus multilocularis carboxylesterase 5A 0.0074 0.016 0.0175
Trichomonas vaginalis DNA helicase recq1, putative 0.0049 0.009 0.0455
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0049 0.011
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0005 0.0025
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0006 0.0029
Trypanosoma brucei glucose transporter 2A 0.0033 0.0047 0.0298
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0024 0.0123
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0042 0.0046
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0712 0.1938 0.3296
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0162 0.0821
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.0009 0.0021
Schistosoma mansoni importin beta-1 0.0151 0.0376 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Schistosoma mansoni hypothetical protein 0.0274 0.0717 0.1219
Brugia malayi hypothetical protein 0.0469 0.1263 0.3464
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0006 0.0013
Echinococcus multilocularis long chain fatty acid transport protein 4 0.1225 0.3369 0.3669
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0115 0.0275 0.0754
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0028 0.0033 0.0168
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0118 0.0282 0.0843
Trypanosoma cruzi mitochondrial protein 99, putative 0.0028 0.0033 0.0092
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0017 0.0002 0.0009
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0059 0.0117 0.0348
Echinococcus multilocularis peregrin 0.0069 0.0146 0.0159
Loa Loa (eye worm) hypothetical protein 0.0067 0.014 0.0314
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0042 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Schistosoma mansoni hypothetical protein 0.1938 0.5356 0.9109
Leishmania major GTP-binding protein, putative 0.009 0.0204 0.0609
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0246 0.0726
Loa Loa (eye worm) steroid hormone receptor 0.0126 0.0306 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0126 0.0306 0.084
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0264 0.0789
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0009 0.0015
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0054 0.0122
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0035 0.022
Echinococcus granulosus ecdysone induced protein 78C 0.0126 0.0306 0.0521
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0054 0.0122
Brugia malayi nuclear receptor RXR 0.0067 0.014 0.0384
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0054 0.0149
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0048 0.0245
Onchocerca volvulus 0.0194 0.0496 0.3249
Echinococcus multilocularis survival motor neuron protein 1 0.0469 0.1263 0.1375
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0274 0.0717 0.0781
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0032 0.016
Schistosoma mansoni ap endonuclease 0.0139 0.0343 0.0583
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0079 0.0843
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0089 0.0152
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0564 0.1526 0.1525
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0009 0.0021
Plasmodium falciparum pyruvate kinase 0.0036 0.0054 0.0427
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0028 0.0033 0.0202
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0032 0.0043 0.0272
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0115 0.0275 0.0273
Brugia malayi hypothetical protein 0.0067 0.014 0.0384
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0019 0.005
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0028 0.0033 0.0055
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0054
Trichomonas vaginalis glycoside hydrolase, putative 0.0724 0.1973 1
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0054 0.0355
Echinococcus multilocularis ecdysone induced protein 78C 0.0126 0.0306 0.0333
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0074 0.0215
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0017 0.0002 0.0009
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0089 0.0586
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0162 0.0836
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.0233
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0241 0.0627 0.1716
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0079 0.023
Leishmania major DNA polymerase kappa, putative 0.0019 0.0006 0.0013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0383 0.1023 0.2806
Onchocerca volvulus 0.0017 0.0002 0.0011
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0006 0.0011
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0017 0.0002 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0126 0.0306 0.0333
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0047 0.0086 0.0094
Loa Loa (eye worm) hypothetical protein 0.0067 0.014 0.0314
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0241 0.0627 0.1716
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0089 0.0152
Brugia malayi kap beta 3 protein 0.0029 0.0034 0.0093
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0383 0.1023 0.174
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0122 0.0133
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0036 0.0056 0.0054
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0002 0.0005
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0126 0.0306 0.2005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0131 0.0222
Toxoplasma gondii aldehyde dehydrogenase 0.018 0.0456 0.2981
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0075 0.0127
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.004 0.0068
Loa Loa (eye worm) RecQ helicase 0.0049 0.009 0.0201
Brugia malayi hypothetical protein 0.0067 0.014 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Brugia malayi AMP-binding enzyme family protein 0.0115 0.0275 0.0754
Brugia malayi latrophilin 2 splice variant baaae 0.0591 0.1602 0.4395
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0306 0.0521
Echinococcus multilocularis solute carrier family 5 0.0189 0.0481 0.0524
Plasmodium falciparum mitogen-activated protein kinase 2 0.0175 0.0442 0.3586
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Schistosoma mansoni smad1 5 8 and 0.0025 0.0024 0.0041
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.0009 0.0021
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0055 0.016
Giardia lamblia Histone acetyltransferase GCN5 0.0081 0.0181 0.5259
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0055 0.0279
Schistosoma mansoni hypothetical protein 0.1938 0.5356 0.9109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0306 0.0333
Plasmodium falciparum histone acetyltransferase GCN5 0.0081 0.0181 0.146
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0173 0.1395
Brugia malayi Thioredoxin reductase 0.013 0.0315 0.0865
Brugia malayi Glycosyl hydrolases family 31 protein 0.0336 0.0891 0.2444
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0028 0.0033 0.0168
Brugia malayi ecdysteroid receptor 0.0126 0.0306 0.084
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0379 0.1011 0.5124
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0122 0.0788
Echinococcus granulosus geminin 0.1938 0.5356 0.9109
Echinococcus granulosus sodium:glucose cotransporter 2 0.0189 0.0481 0.0819
Entamoeba histolytica acetyltransferase, GNAT family 0.0081 0.0181 0.0935
Echinococcus multilocularis dna polymerase eta 0.006 0.0122 0.0133
Schistosoma mansoni ap endonuclease 0.0139 0.0343 0.0583
Echinococcus granulosus survival motor neuron protein 1 0.0469 0.1263 0.2147
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0173 0.1124
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Brugia malayi beta-lactamase 0.0564 0.1526 0.4188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0126 0.0306 0.0687
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0031 0.004 0.025
Echinococcus multilocularis importin 5 0.0029 0.0034 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0178 0.0488
Schistosoma mansoni ATPase 0.0017 0.0002 0.0003
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0044 0.0048
Schistosoma mansoni alpha-glucosidase 0.0289 0.0761 0.1293
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0131 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0306 0.084
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0296 0.0778 0.0777
Echinococcus granulosus GPCR family 2 0.0274 0.0717 0.1219
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.0079 0.0218
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0089 0.0202 0.1312
Brugia malayi nuclear receptor NHR-88 0.006 0.012 0.033
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0108 0.0254 0.0277
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.0079 0.0509
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0009 0.0021
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0042 0.0072
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0139 0.0343 0.0936
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0126 0.0306 0.084
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0017 0.0002 0.0003
Mycobacterium ulcerans hypothetical protein 0.0115 0.0275 0.075
Schistosoma mansoni hypothetical protein 0.002 0.001 0.0017
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0044 0.1242
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.0067 0.014 0.0314
Brugia malayi Ets-domain containing protein 0.007 0.0149 0.0409
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0024 0.0022 0.0061
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0002 0.0009
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0042 0.033
Brugia malayi hypothetical protein 0.0178 0.0451 0.1236
Mycobacterium ulcerans hypothetical protein 0.0019 0.0006 0.0012
Brugia malayi Doublecortin family protein 0.0043 0.0075 0.0205
Brugia malayi Nuclear hormone receptor-like 1 0.0126 0.0306 0.084
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.009 0.0204 0.1327
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0034 0.005 0.0314
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0052 0.0057
Brugia malayi Nuclear hormone receptor E75 0.006 0.012 0.033
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0009 0.0016
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0049 0.0084
Toxoplasma gondii HEAT repeat-containing protein 0.0151 0.0376 0.2454
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0059 0.0117 0.0116
Leishmania major fatty acid transporter protein-like protein 0.1209 0.3324 1
Plasmodium falciparum glutathione reductase 0.0045 0.0079 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0139 0.0343 0.2775
Echinococcus granulosus histone acetyltransferase KAT2B 0.0294 0.0773 0.1314
Brugia malayi ecdysone receptor 0.006 0.012 0.033
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0044 0.0075
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0548 0.1483 0.3327
Schistosoma mansoni cpg binding protein 0.0149 0.037 0.063
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.007 0.0447
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0046 0.0126
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0115 0.0275 0.0273
Brugia malayi Pre-SET motif family protein 0.0217 0.0558 0.1531
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Brugia malayi hypothetical protein 0.0043 0.0075 0.0205
Brugia malayi glutaminase DH11.1 0.0546 0.1477 0.4052
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0108 0.0297
Trichomonas vaginalis ran, putative 0.009 0.0204 0.1034
Echinococcus granulosus long chain fatty acid transport protein 4 0.1225 0.3369 0.5729
Brugia malayi Ets-domain containing protein 0.007 0.0149 0.0409
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.013
Leishmania major hypothetical protein, conserved 0.002 0.0009 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0122 0.033
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0024 0.0041
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0162 0.0363
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0383 0.1023 0.174
Echinococcus granulosus copper transporting ATPase 1 0.0017 0.0002 0.0003
Onchocerca volvulus Fatty acid synthase homolog 0.0044 0.0077 0.0501
Echinococcus granulosus peptidase Clp S14 family 0.0059 0.0117 0.0199
Plasmodium vivax calcium-dependent protein kinase, putative 0.0034 0.005 0.0314
Mycobacterium ulcerans acyl-CoA synthetase 0.0115 0.0275 0.075
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0126 0.0306 0.084
Schistosoma mansoni smad 0.0025 0.0024 0.0041
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0122 0.033
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0047 0.0137
Echinococcus multilocularis traf and tnf receptor associated protein 0.0028 0.0033 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0122
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 0.0552
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0264 0.0449
Schistosoma mansoni hypothetical protein 0.2126 0.588 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0139 0.0343 1
Echinococcus multilocularis high affinity choline transporter 1 0.0189 0.0481 0.0524
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0296 0.0778 0.0777
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0017 0.0002 0.0009
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0028 0.0033 0.0251
Echinococcus granulosus acetylcholinesterase 0.0074 0.016 0.0273
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0118 0.0282 0.0769
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0162 0.0821
Mycobacterium ulcerans acetyl-CoA synthetase 0.0115 0.0275 0.075
Mycobacterium ulcerans thioesterase TesA 0.002 0.0011 0.0025
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0006 0.0029
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0049 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Onchocerca volvulus 0.0049 0.0089 0.0586
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0006 0.0013
Echinococcus multilocularis tumor protein p63 0.034 0.0902 0.0982
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0306 0.084
Brugia malayi mbt repeat family protein 0.0049 0.0089 0.0246
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0049 0.0312
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0026 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0029
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0079 0.023
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0109
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0006 0.0013
Brugia malayi Carboxylesterase family protein 0.0074 0.016 0.044
Brugia malayi Sodium:solute symporter family protein 0.0189 0.0481 0.1321
Brugia malayi MH2 domain containing protein 0.0025 0.0024 0.0066
Plasmodium falciparum importin beta, putative 0.0151 0.0376 0.3044
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0028 0.0033 0.0092
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0032 0.016
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0032 0.0086
Schistosoma mansoni ran 0.009 0.0204 0.0347
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0126 0.0306 0.0521
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0034 0.005 0.0314
Echinococcus granulosus acetylcholinesterase 0.0074 0.016 0.0273
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0036 0.0056 0.0054
Mycobacterium leprae Polyketide synthase Pks13 0.0036 0.0056 0.0162
Leishmania major acetyl-CoA synthetase, putative 0.0115 0.0275 0.0823
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0048 0.0307
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0264 0.7681
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.0079 0.0509
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0089 0.0203 0.0455
Loa Loa (eye worm) hypothetical protein 0.0115 0.0275 0.0617
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Brugia malayi RNA, U transporter 1 0.043 0.1153 0.3165
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Brugia malayi jmjC domain containing protein 0.0201 0.0514 0.1409
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0059 0.0466
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0049 0.0387
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0021 0.096
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0264 0.0449
Mycobacterium tuberculosis Probable exported protein 0.0028 0.0033 0.0031
Entamoeba histolytica hypothetical protein 0.0712 0.1938 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0274 0.0717 0.1609
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0073
Loa Loa (eye worm) nuclear receptor NHR-67 0.006 0.012 0.027
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0002 0.0003
Brugia malayi Na,K-ATPase alpha subunit 0.0017 0.0002 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0548 0.1483 0.7515
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0125 0.0212
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0178 0.0399
Schistosoma mansoni eyes absent homolog 0.0178 0.0451 0.0766
Giardia lamblia Pyruvate kinase 0.0036 0.0054 0.1539
Schistosoma mansoni DNA polymerase eta 0.006 0.0122 0.0207
Loa Loa (eye worm) hypothetical protein 0.0151 0.0376 0.0843
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0691 0.1879 0.4217
Entamoeba histolytica hypothetical protein 0.0123 0.0296 0.1528
Leishmania major pyruvate kinase 0.0036 0.0054 0.0158
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0007 0.0032
Brugia malayi exodeoxyribonuclease III family protein 0.0139 0.0343 0.0941
Loa Loa (eye worm) hypothetical protein 0.0115 0.0275 0.0617
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0047 0.0135
Trichomonas vaginalis glutaminase, putative 0.0546 0.1477 0.7485
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0075 0.0081
Brugia malayi polk-prov protein 0.0019 0.0006 0.0017
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0089 0.0152
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0173 0.1124
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0067 0.014 0.0314
Schistosoma mansoni hypothetical protein 0.0096 0.0221 0.0376
Brugia malayi Pre-SET motif family protein 0.0034 0.0048 0.0133
Giardia lamblia DINP protein human, muc B family 0.006 0.0122 0.3523
Onchocerca volvulus Huntingtin homolog 0.0122 0.0293 0.192
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0002 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0241 0.0627 0.1066
Echinococcus granulosus dna polymerase kappa 0.006 0.0122 0.0207
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0125 0.0808
Mycobacterium ulcerans aldehyde dehydrogenase 0.018 0.0456 0.1248
Schistosoma mansoni protein kinase 0.0034 0.005 0.0084
Echinococcus multilocularis acetylcholinesterase 0.0074 0.016 0.0175
Echinococcus multilocularis phd:f box containing protein 0.002 0.0009 0.001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.005 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0005 0.0024
Leishmania major DNA polymerase eta, putative 0.006 0.0122 0.0362
Schistosoma mansoni carbon catabolite repressor protein 0.0028 0.0033 0.0055
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0125 0.028
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0022 0.002
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0049 0.0143
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0028 0.0033 0.0073
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 0.59
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Schistosoma mansoni intermediate filament proteins 0.008 0.0178 0.0303
Trichomonas vaginalis beta-galactosidase, putative 0.0724 0.1973 1
Schistosoma mansoni DNA helicase recq1 0.0032 0.0042 0.0072
Echinococcus granulosus nuclear receptor nhr 48 0.006 0.012 0.0204
Entamoeba histolytica protein kinase, putative 0.0034 0.005 0.0256
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0115 0.0275 0.2223
Leishmania major hypothetical protein, conserved 0.0079 0.0173 0.0516
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0048 0.0245
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0306 0.084
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0009 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0306 0.084
Echinococcus multilocularis General substrate transporter 0.0092 0.0212 0.0231
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0079 0.023
Brugia malayi Steroid receptor seven-up type 2 0.0126 0.0306 0.084
Entamoeba histolytica acyl-CoA synthetase, putative 0.0118 0.0282 0.1454
Schistosoma mansoni rab6-interacting 0.0043 0.0075 0.0127
Toxoplasma gondii thioredoxin reductase 0.013 0.0315 0.2057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1209 0.3324 0.3323
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0076
Schistosoma mansoni Smad4 0.0025 0.0024 0.0041
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Loa Loa (eye worm) fli-1 protein 0.0212 0.0546 0.1225
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.0079 0.0509
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1615 0.4457 1
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Brugia malayi Importin beta-1 subunit 0.0151 0.0376 0.1031
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0122 0.012
Echinococcus granulosus lamin dm0 0.008 0.0178 0.0303
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0108 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0126 0.0306 0.0521
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0009
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 0.5141
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Echinococcus multilocularis pyruvate kinase 0.0036 0.0054 0.0059
Schistosoma mansoni gabp alpha 0.007 0.0149 0.0254
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.009 0.0204 0.1327
Schistosoma mansoni neutral sphingomyelinase 0.0028 0.0033 0.0055
Brugia malayi beta-lactamase family protein 0.0564 0.1526 0.4188
Loa Loa (eye worm) hypothetical protein 0.0126 0.0306 0.0687
Plasmodium falciparum phd finger protein, putative 0.0061 0.0125 0.1002
Trichomonas vaginalis glucosylceramidase, putative 0.036 0.0957 0.4851
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0009 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0126 0.0306 0.0687
Loa Loa (eye worm) sugar transporter 0.0108 0.0254 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0009 0.002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.0254 0.0432
Brugia malayi Cytochrome P450 family protein 0.0047 0.0086 0.0237
Schistosoma mansoni hypothetical protein 0.0274 0.0717 0.1219
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0044 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0048 0.0053
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0296 0.0778 0.0777
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.0009 0.0046
Brugia malayi glutathione reductase 0.013 0.0315 0.0865
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0021 0.0127
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0131 0.0222
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0024 0.0054
Schistosoma mansoni inositol transporter 0.0189 0.0481 0.0819
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0024 0.0026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0115 0.0275 0.0823
Plasmodium falciparum thioredoxin reductase 0.013 0.0315 0.2552
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0011 0.0028
Plasmodium falciparum DNase I-like protein, putative 0.0028 0.0033 0.0251
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0007 0.0015
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0025
Plasmodium vivax importin-beta 2, putative 0.0151 0.0376 0.2454
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Onchocerca volvulus 0.0028 0.0033 0.0213
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0264 0.0778
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0028 0.0033 0.0089
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0126 0.0306 0.0521
Brugia malayi nuclear hormone receptor family member odr-7 0.006 0.012 0.033
Giardia lamblia DNA damage repair protein 0.0019 0.0006 0.0131
Loa Loa (eye worm) hypothetical protein 0.0067 0.014 0.0314
Schistosoma mansoni glutaminase 0.0546 0.1477 0.2512
Echinococcus multilocularis cation transporting ATPase 13A3 0.0017 0.0002 0.0002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0202
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0139 0.0343 0.2237
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.0079 0.0233
Brugia malayi AMP-binding enzyme family protein 0.0115 0.0275 0.0754
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0006 0.0029
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0009 0.0046
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0002 0.0002
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.0149 0.037 0.0831
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0073
Echinococcus granulosus lamin 0.008 0.0178 0.0303
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0054
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.0246 0.0419
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.0126 0.0306 0.0521
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0007 0.0015
Schistosoma mansoni nuclear receptor 0.006 0.012 0.0204
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Giardia lamblia Pyruvate kinase 0.0018 0.0005 0.0111
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0047 0.0298
Plasmodium vivax JmjC domain containing protein 0.002 0.0009 0.0049
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0029 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0694 0.1888 0.4237
Mycobacterium tuberculosis Probable hydrolase 0.0564 0.1526 0.1525
Echinococcus multilocularis neuropeptide s receptor 0.0922 0.2524 0.2749
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0048 0.0082
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.009 0.0204 0.1327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0048 0.0245
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0034 0.005 0.0314
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0061 0.0066
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0162 0.0821
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.006 0.012 0.027
Plasmodium vivax SET domain protein, putative 0.0034 0.0048 0.0307
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0115 0.0275 0.1792
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0009 0.0049
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.0809 0.2429
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0002 0.0009
Echinococcus multilocularis smad 0.0025 0.0024 0.0026
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0075 0.0127
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0028 0.0033 0.0093
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0031 0.004 0.0115
Loa Loa (eye worm) hypothetical protein 0.0274 0.0717 0.1609
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0028 0.0033 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0122 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0048 0.0245
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0044 0.0227
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0089 0.0203 0.0221
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0162 0.0821
Echinococcus multilocularis thioredoxin glutathione reductase 0.0131 0.0318 0.0347
Brugia malayi F/Y-rich N-terminus family protein 0.0067 0.014 0.0385
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0052 0.0152
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.014 0.0238
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0122 0.0788
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0049 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0246 0.1248
Trypanosoma brucei glucose transporter, putative 0.0033 0.0047 0.0298
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0028 0.0033 0.0073
Schistosoma mansoni hypothetical protein 0.0035 0.0052 0.0089
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0131 0.0359
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0009 0.0016
Loa Loa (eye worm) thioredoxin reductase 0.013 0.0315 0.0708
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0028 0.0033 0.0168
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0203 0.1637
Schistosoma mansoni cpg binding protein 0.0158 0.0394 0.067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.006 0.012 0.0204
Schistosoma mansoni pyruvate kinase 0.0018 0.0005 0.0009
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0028 0.0033 0.0168
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0028 0.0033 0.0093
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.018 0.0456 0.1368
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0126 0.0306 0.0521
Leishmania major glucose transporter, lmgt3 0.0033 0.0047 0.0137
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0359 0.106
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0075 0.0168
Onchocerca volvulus Bile acid receptor homolog 0.0126 0.0306 0.2005
Echinococcus multilocularis GTP binding nuclear protein Ran 0.009 0.0204 0.0222
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0017 0.0002 0.0009
Brugia malayi Probable ClpP-like protease 0.0089 0.0203 0.0557
Echinococcus granulosus FTZ F1 alpha 0.0126 0.0306 0.0521
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0029 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0089 0.0202 0.1023
Entamoeba histolytica hypothetical protein 0.0018 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0239
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0002 0.0009
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0115 0.0275 0.075
Echinococcus granulosus Smad4 0.0025 0.0024 0.0041
Entamoeba histolytica protein kinase, putative 0.0034 0.005 0.0256
Brugia malayi AMP-binding enzyme family protein 0.0138 0.0338 0.0929
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0028 0.0033 0.0202
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0173 0.0509
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0017 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0029
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0046 0.0126
Brugia malayi isocitrate dehydrogenase 0.0034 0.0049 0.0135
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0115 0.0275 0.0823
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0009 0.0021
Echinococcus multilocularis neutral sphingomyelinase 0.0028 0.0033 0.0035
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0021 0.0047
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0055 0.035

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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