Detailed information for compound 107210

Basic information

Technical information
  • TDR Targets ID: 107210
  • Name: N-(3-oxobenzo[f]chromen-2-yl)acetamide
  • MW: 253.253 | Formula: C15H11NO3
  • H donors: 1 H acceptors: 2 LogP: 2.55 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1cc2c(oc1=O)ccc1c2cccc1
  • InChi: 1S/C15H11NO3/c1-9(17)16-13-8-12-11-5-3-2-4-10(11)6-7-14(12)19-15(13)18/h2-8H,1H3,(H,16,17)
  • InChiKey: GLGOAFMFRQOUSV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-oxo-2-benzo[f][1]benzopyranyl)acetamide
  • N-(3-oxobenzo[f]chromen-2-yl)ethanamide
  • N-(3-ketobenzo[f]chromen-2-yl)acetamide
  • N-(3-oxo-2-benzo[f]chromenyl)acetamide
  • ChemDiv3_002032
  • Oprea1_087569
  • MLS000723814
  • N-(3-oxo-3H-benzo[f]chromen-2-yl)acetamide
  • SMR000305409
  • IDI1_020998

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens galactosidase, alpha Starlite/ChEMBL No references
Homo sapiens glucosidase, beta, acid Starlite/ChEMBL No references
Homo sapiens sphingomyelin phosphodiesterase 1, acid lysosomal Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Alpha-N-acetylgalactosaminidase, putative Get druggable targets OG5_127620 All targets in OG5_127620
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi O-Glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus granulosus Alpha N acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Brugia malayi Melibiase family protein Get druggable targets OG5_127620 All targets in OG5_127620
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis Alpha N acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128629 All targets in OG5_128629
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127620 All targets in OG5_127620
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Alpha-N-acetylgalactosaminidase, putative Get druggable targets OG5_127620 All targets in OG5_127620
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Onchocerca volvulus Glucosylceramidase homolog Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus multilocularis Glycoside hydrolase, family 27 Get druggable targets OG5_127620 All targets in OG5_127620
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative Get druggable targets OG5_128629 All targets in OG5_128629
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative Get druggable targets OG5_127620 All targets in OG5_127620
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Alpha-N-acetylgalactosaminidase precursor, putative Get druggable targets OG5_127620 All targets in OG5_127620
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum expressed protein Get druggable targets OG5_127620 All targets in OG5_127620
Schistosoma japonicum Alpha-N-acetylgalactosaminidase, putative Get druggable targets OG5_127620 All targets in OG5_127620
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Neospora caninum hypothetical protein Get druggable targets OG5_127620 All targets in OG5_127620
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii melibiase subfamily protein Get druggable targets OG5_127620 All targets in OG5_127620
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K01204 alpha-N-acetylgalactosaminidase [EC3.2.1.49], putative Get druggable targets OG5_127620 All targets in OG5_127620
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative Get druggable targets OG5_128629 All targets in OG5_128629
Candida albicans one of four genes similar to C. elegans asm2 lysosomal acid sphingomyelin phosphodiesterase (XL940) Get druggable targets OG5_128629 All targets in OG5_128629
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase Get druggable targets OG5_127620 All targets in OG5_127620
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Cathepsin B precursor 0.0121 0.0282 0.0885
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0056 0.0106 0.0232
Onchocerca volvulus 0.0199 0.0494 0.0953
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0121 0.0282 0.2041
Mycobacterium ulcerans proteasome PrcB 0.008 0.017 0.0701
Schistosoma mansoni myst-related protein 0.0026 0.0023 0.0049
Loa Loa (eye worm) cathepsin B 0.0548 0.1437 0.3176
Loa Loa (eye worm) hypothetical protein 0.0048 0.0084 0.0183
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0081 0.0172 0.0558
Giardia lamblia DNA damage repair protein 0.0065 0.0129 0.0389
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0048 0.0084 0.0209
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0268 0.0596
Schistosoma mansoni intermediate filament proteins 0.0033 0.0042 0.0091
Plasmodium vivax unspecified product 0.0121 0.0282 0.2041
Echinococcus multilocularis lamin 0.0033 0.0042 0.0039
Echinococcus granulosus cathepsin b 0.1501 0.4017 1
Brugia malayi hypothetical protein 0.0514 0.1345 0.2973
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0037 0.0053 0.0117
Brugia malayi Cathepsin L-like cysteine proteinase 0.0327 0.0839 0.1854
Brugia malayi Importin beta-1 subunit 0.0028 0.003 0.0065
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0052 0.0094 0.0207
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Leishmania major mitochondrial DNA polymerase beta 0.0901 0.2394 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0041 0.0065 0.0155
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0197 0.0195
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0028 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0246 0.0619 0.1381
Plasmodium vivax acyl-CoA synthetase, putative 0.0183 0.0449 0.3271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0173 0.0422 0.1089
Echinococcus granulosus PHD finger protein rhinoceros 0.0026 0.0024 0.0054
Schistosoma mansoni importin beta-1 0.0028 0.003 0.0065
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.045 0.1173 0.3812
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0049 0.0344
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.004 0.0063 0.0436
Echinococcus multilocularis casein kinase ii subunit alpha 0.0121 0.0282 0.0279
Mycobacterium tuberculosis Probable oxidoreductase 0.1324 0.3539 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0209 0.052 0.0517
Trypanosoma cruzi cysteine peptidase, putative 0.0367 0.0947 0.2357
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0028 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0059 0.0113 0.025
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0155 0.0373 0.0823
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.01 0.0224 0.0726
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.008 0.017 0.0422
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.008 0.0171 0.0381
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.008 0.017 0.055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1501 0.4017 0.8973
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0173 0.0422 0.1089
Schistosoma mansoni hypothetical protein 0.015 0.0361 0.0803
Brugia malayi ImpB/MucB/SamB family protein 0.0209 0.052 0.1147
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.0727 0.1804
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0037 0.0055 0.0121
Trypanosoma cruzi DNA polymerase kappa, putative 0.0233 0.0584 0.1454
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.005 0.009 0.0262
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0041 0.0065 0.0155
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0457 0.1192 0.2662
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0156 0.0381
Echinococcus multilocularis Niemann Pick C1 protein 0.0644 0.1697 0.1695
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0038 0.0058 0.0126
Toxoplasma gondii cathepsin CPL 0.0331 0.0851 0.592
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0037 0.008
Loa Loa (eye worm) patched family protein 0.0027 0.0028 0.0059
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0036 0.0051 0.0112
Echinococcus granulosus ubiquitin specific protease 41 0.0155 0.0373 0.0923
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0155 0.0373 0.0823
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0282 0.0528
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0124 0.0289 0.0286
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0052 0.0094 0.0395
Schistosoma mansoni transcription factor LCR-F1 0.0226 0.0567 0.1264
Echinococcus granulosus cysteine protease 0.0125 0.0293 0.0723
Loa Loa (eye worm) glutaminase 2 0.0658 0.1734 0.3834
Leishmania major hypothetical protein, conserved 0.0048 0.0084 0.035
Echinococcus granulosus phd:f box containing protein 0.0027 0.0028 0.0063
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0072 0.0148 0.0363
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0181 0.0444 0.0979
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0048 0.0084 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0049 0.0076
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0121 0.0282 0.2041
Echinococcus multilocularis PHD finger protein rhinoceros 0.0026 0.0024 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0327 0.0839 0.1854
Mycobacterium leprae Probable lipase LipE 0.0071 0.0145 0.0297
Loa Loa (eye worm) hypothetical protein 0.0469 0.1222 0.2702
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0548 0.1437 0.2775
Leishmania major histone deacetylase, putative 0.0043 0.0071 0.0298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0282 0.0528
Brugia malayi Patched related family protein 10 0.0027 0.0028 0.0059
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0143 0.0341 0.0752
Trypanosoma cruzi cysteine peptidase, putative 0.0331 0.0851 0.2118
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0282 0.0528
Onchocerca volvulus 0.0036 0.0051 0.0094
Brugia malayi Peptidase family M1 containing protein 0.0037 0.0053 0.0116
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1324 0.3539 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0072 0.0148 0.0307
Plasmodium falciparum histone deacetylase 2 0.0043 0.0071 0.05
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Schistosoma mansoni kinase 0.0111 0.0255 0.0566
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Mycobacterium ulcerans beta-lactamase 0.0071 0.0145 0.0556
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0143 0.0341 0.0759
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0033 0.0218
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0048 0.0084 0.0192
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0038 0.0058 0.0401
Echinococcus granulosus thioredoxin glutathione reductase 0.0527 0.1381 0.3434
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0145 0.0297
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0145 0.0297
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Treponema pallidum oxidoreductase 0.0048 0.0084 0.007
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Brugia malayi hypothetical protein 0.0286 0.0727 0.1606
Onchocerca volvulus Serine\/threonine kinase homolog 0.0218 0.0544 0.105
Leishmania major phosphopantetheinyl transferase-like protein 0.004 0.0063 0.0261
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0029 0.0033 0.0075
Plasmodium falciparum thioredoxin reductase 0.0522 0.1368 1
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0187 0.046 0.0875
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0125 0.0293 0.0652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0245 0.0617 0.3361
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0037 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0049 0.0123
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0094 0.0235
Echinococcus granulosus SAM and MBT domain containing protein 0.0036 0.0051 0.0121
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0048 0.0084 0.035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Brugia malayi proteasome subunit beta type 1 0.0062 0.0121 0.0266
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0072 0.0148 0.062
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0158 0.0382 0.0945
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0155 0.0373 0.0706
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0158 0.0382 0.038
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Trichomonas vaginalis glutaminase, putative 0.0658 0.1734 0.3353
Echinococcus multilocularis Ankyrin 0.0031 0.0037 0.0035
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0072 0.0148 0.037
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0177 0.0439
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0548 0.1437 0.3577
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0181 0.0444 0.3088
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0538 0.1026
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0038 0.0058 0.0126
Brugia malayi Melibiase family protein 0.0082 0.0177 0.039
Echinococcus granulosus histone deacetylase 7 0.0043 0.0071 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0145 0.0263
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0121 0.0282 0.0885
Loa Loa (eye worm) mbt repeat family protein 0.0036 0.0051 0.0111
Trichomonas vaginalis helicase, putative 0.0045 0.0076 0.0128
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0181 0.0444 1
Leishmania major DNA polymerase kappa, putative 0.0065 0.0129 0.054
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0121 0.0282 0.0528
Trypanosoma cruzi cysteine peptidase, putative 0.0367 0.0947 0.2357
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0048 0.0084 0.0209
Leishmania major DNA damage repair protein, putative 0.0065 0.0129 0.054
Loa Loa (eye worm) hypothetical protein 0.0245 0.0617 0.1363
Plasmodium vivax vivapain-3 0.0125 0.0293 0.2124
Echinococcus multilocularis fibrillin 1 0.0023 0.0015 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0245 0.0617 0.2004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0071 0.0155
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0048 0.0084 0.0122
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.0079
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0109 0.0248 0.0547
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Entamoeba histolytica aminopeptidase, putative 0.0037 0.0053 0.0173
Brugia malayi polk-prov protein 0.0089 0.0194 0.0427
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0048 0.0084 0.035
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0082 0.0177 0.0325
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0181 0.0444 0.1854
Plasmodium vivax acetyl-CoA synthetase, putative 0.0072 0.0148 0.1067
Schistosoma mansoni glutamate synthase 0.0048 0.0084 0.0185
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0043 0.0137
Entamoeba histolytica cysteine proteinase 1, putative 0.0125 0.0293 0.0951
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0048 0.0084 0.0122
Trypanosoma cruzi major cysteine proteinase, putative 0.0121 0.0282 0.0701
Plasmodium falciparum serine repeat antigen 5 0.0121 0.0282 0.2041
Echinococcus granulosus glutamate synthase 0.0048 0.0084 0.0202
Echinococcus granulosus lamin 0.0033 0.0042 0.0098
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0181 0.0444 0.0989
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0076 0.0128
Trypanosoma brucei glucosidase, putative 0.0035 0.0049 0.0206
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0049 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.004 0.0063 0.0066
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0055 0.0102 0.0255
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0049 0.0206
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.005 0.009 0.0092
Schistosoma mansoni hypothetical protein 0.0186 0.0458 0.1021
Trypanosoma brucei unspecified product 0.0144 0.0344 0.1437
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0372 0.0926
Trichomonas vaginalis chaperonin, putative 0.0029 0.0033 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Brugia malayi Csnk2b protein 0.0033 0.0043 0.0092
Loa Loa (eye worm) patched family protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0087
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0072 0.0148 0.0326
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.005 0.009 0.072
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Echinococcus multilocularis cysteine protease 0.0331 0.0851 0.0848
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0052
Echinococcus multilocularis aminopeptidase N 0.0037 0.0053 0.0051
Plasmodium vivax histone deacetylase, putative 0.0043 0.0071 0.05
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0181 0.0444 0.323
Mycobacterium ulcerans monoxygenase 0.0048 0.0084 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Leishmania major GTP-binding protein, putative 0.0021 0.001 0.0042
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0177 0.1272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Mycobacterium tuberculosis Conserved protein 0.0071 0.0145 0.0297
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0048 0.0084 0.0202
Loa Loa (eye worm) 6-phosphofructokinase 0.0187 0.046 0.1015
Loa Loa (eye worm) inositol-1 0.0036 0.0051 0.0112
Plasmodium falciparum acyl-CoA synthetase 0.0183 0.0449 0.3271
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0175 0.0427 0.0951
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0028 0.006
Entamoeba histolytica hypothetical protein 0.0026 0.0023 0.0074
Loa Loa (eye worm) hypothetical protein 0.0128 0.0302 0.0665
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0121 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0121 0.0282 0.2041
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0331 0.0851 0.1879
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0181 0.0444 0.0441
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.007 0.0142 0.0347
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0245 0.0617 0.3361
Plasmodium falciparum T-complex protein 1 subunit beta 0.0029 0.0033 0.0219
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0016 0.0011
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0035 0.0049 0.0107
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0084 0.035
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0048 0.0084 0.0202
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0062 0.0121 0.0296
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0094 0.0235
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.004 0.0169
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Plasmodium vivax vivapain-2 0.0331 0.0851 0.6211
Brugia malayi hypothetical protein 0.0215 0.0537 0.1186
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.001 0.0025
Plasmodium vivax vivapain-2 0.0331 0.0851 0.6211
Brugia malayi Pre-SET motif family protein 0.0246 0.0619 0.1367
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0218 0.0544 0.0541
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0071 0.0177
Loa Loa (eye worm) hypothetical protein 0.0183 0.0449 0.0992
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0069 0.014 0.0586
Mycobacterium leprae conserved hypothetical protein 0.004 0.0063 0.0061
Echinococcus multilocularis lamin dm0 0.0033 0.0042 0.0039
Echinococcus multilocularis muscleblind protein 1 0.1305 0.3487 0.3485
Schistosoma mansoni glutamate synthase 0.0048 0.0084 0.0185
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0048 0.0084 0.0122
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0069 0.014 0.0349
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.007 0.0153
Trypanosoma brucei proteasome beta 6 subunit 0.0062 0.0121 0.0507
Entamoeba histolytica cysteine proteinase 2 0.0125 0.0293 0.0951
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0901 0.2394 0.5959
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0037 0.0081
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0048 0.0084 0.0192
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0037 0.0053 0.0051
Trichomonas vaginalis apoptosis inducing factor, putative 0.0048 0.0084 0.0143
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0049 0.0076
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0121 0.0282 0.2041
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1687 0.4522 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0121 0.0282 0.0621
Trypanosoma brucei DNA polymerase kappa, putative 0.0215 0.0536 0.2237
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0281 0.1366
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0048 0.0084 0.0143
Leishmania major hypothetical protein, conserved 0.0027 0.0028 0.0116
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0062 0.0121 0.0119
Brugia malayi cathepsin F-like cysteine proteinase 0.0121 0.0282 0.0621
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0055 0.0102 0.0427
Loa Loa (eye worm) histone deacetylase 7A 0.0043 0.0071 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Giardia lamblia Proteasome subunit beta type 5 precursor 0.008 0.017 0.052
Plasmodium vivax ferrodoxin reductase, putative 0.0048 0.0084 0.0593
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0065
Mycobacterium ulcerans DNA polymerase IV 0.0233 0.0584 0.3165
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.0373 0.0706
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0048 0.0084 0.0192
Echinococcus multilocularis casein kinase ii subunit beta 0.0033 0.0043 0.004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0026 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Schistosoma mansoni casein kinase II beta subunit 0.0033 0.0043 0.0092
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0051 0.008
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0037 0.0053 0.0051
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0121 0.0281 0.1176
Loa Loa (eye worm) proteasome subunit beta type 1 0.0062 0.0121 0.0266
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0072 0.0148 0.037
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0141
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0049 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0172 0.0315
Schistosoma mansoni jumonji domain containing protein 0.0139 0.033 0.0735
Brugia malayi Patched protein homolog 1 0.0027 0.0028 0.0059
Entamoeba histolytica acyl-CoA synthetase, putative 0.0245 0.0617 0.2004
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0181 0.0444 0.1099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Schistosoma mansoni cathepsin B (C01 family) 0.0121 0.0282 0.0627
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0062 0.0121 0.0229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0197 0.0438
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0121 0.0282 0.2041
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Schistosoma mansoni patched 1 0.0193 0.0477 0.1064
Giardia lamblia Cathepsin B precursor 0.0121 0.0282 0.0885
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0072 0.0148 0.062
Onchocerca volvulus 0.0331 0.0851 0.1646
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0074 0.0154 0.0643
Trypanosoma cruzi cruzipain precursor, putative 0.0367 0.0947 0.2357
Trichomonas vaginalis glutamate synthase, putative 0.0048 0.0084 0.0143
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0081 0.0172 0.0719
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0145 0.0297
Schistosoma mansoni SET domain protein 0.0027 0.0026 0.0055
Trichomonas vaginalis 6-phosphofructokinase, putative 0.005 0.009 0.0156
Brugia malayi Patched related family protein 12 0.0027 0.0028 0.0059
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1191 0.3179 0.8971
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0062 0.0121 0.0302
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0508 0.0981
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0028 0.0063
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0072 0.0148 0.0307
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0121 0.0282 0.2041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0072 0.0148 0.0326
Onchocerca volvulus Cathepsin L homolog 0.0331 0.0851 0.1646
Toxoplasma gondii propionate-CoA ligase 0.0072 0.0148 0.1033
Echinococcus granulosus regulator of G protein signaling 7 0.0029 0.0031 0.0071
Leishmania major cathepsin L-like protease 0.0367 0.0947 0.3955
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0028 0.0025
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0033 0.003
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.0586 0.1294
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0072 0.0148 0.0482
Loa Loa (eye worm) hypothetical protein 0.0075 0.0156 0.0344
Mycobacterium ulcerans glutaminase 0.0658 0.1734 1
Plasmodium falciparum casein kinase II beta chain 0.0033 0.0043 0.029
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0024 0.0157
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0145 0.0143
Brugia malayi hypothetical protein 0.0045 0.0075 0.0164
Schistosoma mansoni hypothetical protein 0.0186 0.0458 0.1021
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0048 0.0084 0.0583
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0282 0.0885
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0048 0.0084 0.0122
Loa Loa (eye worm) histone deacetylase 0.0043 0.0071 0.0155
Echinococcus granulosus fetal alzheimer antigen falz 0.0035 0.0049 0.0116
Entamoeba histolytica deoxycytidyl transferase, putative 0.0209 0.052 0.1687
Giardia lamblia Kinase, PLK 0.0218 0.0544 0.1739
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0385 0.0849
Plasmodium vivax DNA repair protein REV1, putative 0.0065 0.0129 0.0926
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Loa Loa (eye worm) hypothetical protein 0.0215 0.0537 0.1186
Loa Loa (eye worm) programmed cell death 8 0.0048 0.0084 0.0183
Schistosoma mansoni DNA polymerase IV / kappa 0.0065 0.0129 0.0287
Giardia lamblia Hypothetical protein 0.0121 0.0282 0.0885
Schistosoma mansoni hypothetical protein 0.007 0.0142 0.0315
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.005 0.009 0.0293
Loa Loa (eye worm) hypothetical protein 0.0327 0.0839 0.1854
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Entamoeba histolytica hypothetical protein 0.004 0.0063 0.0202
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0331 0.0851 0.0848
Plasmodium vivax serine-repeat antigen (SERA) 0.0121 0.0282 0.2041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1154 0.3078 1
Brugia malayi AMP-binding enzyme family protein 0.0245 0.0617 0.1363
Plasmodium vivax casein kinase II beta chain, putative 0.0033 0.0043 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Schistosoma mansoni zinc finger protein 0.0032 0.0041 0.0088
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0029 0.0033 0.0044
Brugia malayi Muscleblind-like protein 0.1305 0.3487 0.771
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1854
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.004 0.0063 0.141
Trichomonas vaginalis phosphofructokinase, putative 0.0187 0.046 0.0875
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trypanosoma brucei histone deacetylase 3 0.0043 0.0071 0.0298
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0081 0.0172 0.0716
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0282 0.0885
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0048 0.0084 0.0271
Entamoeba histolytica casein kinase, putative 0.0121 0.0282 0.0914
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Giardia lamblia PHD finger protein 15 0.0026 0.0024 0.0047
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1501 0.4017 1
Brugia malayi Papain family cysteine protease containing protein 0.0125 0.0293 0.0646
Trypanosoma brucei unspecified product 0.0144 0.0344 0.1437
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0048 0.0084 0.0183
Onchocerca volvulus 0.0331 0.0851 0.1646
Echinococcus granulosus cathepsin L 0.0121 0.0282 0.0695
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0154 0.0609
Plasmodium falciparum ferrodoxin reductase-like protein 0.0048 0.0084 0.0593
Plasmodium falciparum lipid/sterol:H+ symporter 0.0027 0.0028 0.0181
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0048 0.0084 0.0122
Echinococcus multilocularis regulator of G protein signaling 7 0.0029 0.0031 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0128
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0048 0.0084 0.0271
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Brugia malayi glutamate synthase 0.0048 0.0084 0.0183
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0102 0.0332
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0183 0.0449 0.1167
Brugia malayi Kringle domain containing protein 0.0018 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Echinococcus multilocularis musashi 0.0033 0.0042 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0233 0.0584 0.1454
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0121 0.0281 0.0279
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Toxoplasma gondii PHD-finger domain-containing protein 0.0026 0.0024 0.017
Leishmania major casein kinase II, putative 0.0121 0.0282 0.1176
Plasmodium vivax glutathione reductase, putative 0.0522 0.1368 1
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Loa Loa (eye worm) hypothetical protein 0.0093 0.0205 0.0452
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0051 0.008
Plasmodium vivax thioredoxin reductase, putative 0.0522 0.1368 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0121 0.0282 0.0627
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0081 0.0172 0.0169
Mycobacterium ulcerans DNA polymerase IV 0.0233 0.0584 0.3165
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0037 0.0053 0.0127
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0233 0.0584 0.1116
Toxoplasma gondii CMGC kinase, CK2 family 0.0121 0.0282 0.196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Echinococcus multilocularis tumor protein p63 0.0634 0.167 0.1668
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0427 0.1109 0.4631
Entamoeba histolytica acyl-coA synthetase, putative 0.0245 0.0617 0.2004
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0145 0.0263
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0048 0.0084 0.0209
Loa Loa (eye worm) hypothetical protein 0.0183 0.0449 0.0992
Brugia malayi cathepsin L-like precursor 0.0327 0.0839 0.1854
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Onchocerca volvulus 0.0072 0.0148 0.0283
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0026 0.0025 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0427 0.1109 0.276
Leishmania major proteasome beta 5 subunit, putative 0.008 0.017 0.0708
Schistosoma mansoni ran 0.0021 0.001 0.002
Onchocerca volvulus 0.0081 0.0174 0.0332
Echinococcus granulosus muscleblind protein 0.1305 0.3487 0.8679
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0072 0.0148 0.0576
Schistosoma mansoni netrin receptor unc5 0.0031 0.0037 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0245 0.0617 0.3361
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0281 0.1366
Schistosoma mansoni sulfide quinone reductase 0.0048 0.0084 0.0185
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.003 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0544 0.1212
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0072 0.0148 0.0307
Brugia malayi Papain family cysteine protease containing protein 0.0125 0.0293 0.0646
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0106 0.0186
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0062 0.0121 0.0216
Brugia malayi jmjC domain containing protein 0.0116 0.0268 0.059
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0042 0.0091
Brugia malayi Protein kinase domain containing protein 0.0018 0.0003 0.0004
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0094 0.0395
Leishmania major 4-coumarate:coa ligase-like protein 0.0245 0.0617 0.2578
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0175 0.0427 0.1057
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0048 0.0084 0.0202
Echinococcus granulosus Ankyrin 0.0031 0.0037 0.0086
Brugia malayi PHD-finger family protein 0.0026 0.0024 0.0052
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0049 0.0076
Entamoeba histolytica hypothetical protein 0.0036 0.0051 0.0166
Giardia lamblia Kinase, CMGC CK2 0.0121 0.0282 0.0885
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0048 0.0084 0.0583
Echinococcus granulosus dna polymerase eta 0.0277 0.0703 0.1744
Plasmodium falciparum serine repeat antigen 4 0.0121 0.0282 0.2041
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0028 0.0194
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0048 0.0084 0.0271
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Entamoeba histolytica hypothetical protein 0.0226 0.0567 0.184
Loa Loa (eye worm) hypothetical protein 0.0331 0.0851 0.1879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Trichomonas vaginalis antibiotic synthetase, putative 0.0072 0.0148 0.0269
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0281 0.1366
Schistosoma mansoni tsg101-related 0.0147 0.035 0.0781
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0048 0.0084 0.0202
Entamoeba histolytica hypothetical protein 0.0226 0.0567 0.184
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0033 0.0043 0.0106
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0028 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Plasmodium falciparum cysteine proteinase falcipain 3 0.0331 0.0851 0.6211
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0197 0.0195
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1501 0.4017 0.8973
Plasmodium falciparum serine repeat antigen 7 0.0121 0.0282 0.2041
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.0586 0.1294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Brugia malayi exodeoxyribonuclease III family protein 0.0081 0.0172 0.0378
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0282 0.0621
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Mycobacterium tuberculosis Conserved hypothetical protein 0.0209 0.052 0.1368
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0564 0.148 0.4113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Mycobacterium ulcerans dehydrogenase 0.0048 0.0084 0.0192
Brugia malayi cathepsin B-like cysteine proteinase 0.1501 0.4017 0.8883
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0003 0.0003
Brugia malayi CXXC zinc finger family protein 0.0199 0.0494 0.109
Toxoplasma gondii aldehyde dehydrogenase 0.0121 0.0281 0.1958
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0121 0.0282 0.2041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0232 0.0583 0.1446
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0282 0.0528
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0041 0.0065 0.0062
Entamoeba histolytica hypothetical protein 0.0226 0.0567 0.184
Leishmania major hypothetical protein, conserved 0.0018 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0477 0.0908
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.0727 0.0725
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0282 0.0885
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0145 0.0361
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0154 0.0609
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0209 0.052 0.1288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0037 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0901 0.2394 0.5959
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0264 0.0668 0.149
Echinococcus granulosus nuclear factor of activated T cells 5 0.03 0.0767 0.1904
Schistosoma mansoni cpg binding protein 0.0213 0.053 0.1182
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0177 0.1272
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0033 0.0043 0.0178
Trichomonas vaginalis hypothetical protein 0.0024 0.0019 0.0018
Onchocerca volvulus 0.0071 0.0145 0.0276
Plasmodium falciparum serine repeat antigen 6 0.0121 0.0282 0.2041
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.0129 0.054
Loa Loa (eye worm) fibroinase 0.0331 0.0851 0.1879
Giardia lamblia Fructose-bisphosphate aldolase 0.1154 0.3078 1
Loa Loa (eye worm) proteasome subunit beta type 2 0.0038 0.0058 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0194 0.081
Toxoplasma gondii patched family protein 0.0027 0.0028 0.0193
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Echinococcus granulosus Niemann Pick C1 protein 0.045 0.1173 0.2917
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0282 0.0528
Brugia malayi protein C24B5.3 0.0027 0.0028 0.0059
Trypanosoma brucei Casein kinase II 0.0121 0.0282 0.1176
Giardia lamblia NADH oxidase lateral transfer candidate 0.0181 0.0444 0.1413
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0082 0.0177 0.0393
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Leishmania major DNA polymerase eta, putative 0.0132 0.0312 0.1305
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.0839 0.2726
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0059 0.0113 0.0471
Echinococcus multilocularis jumonji domain containing protein 0.0036 0.0052 0.005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0157 0.0377 0.0375
Echinococcus multilocularis glutamate synthase 0.0048 0.0084 0.0081
Schistosoma mansoni cpg binding protein 0.0213 0.053 0.1182
Trichomonas vaginalis rotamase, putative 0.0056 0.0106 0.0186
Schistosoma mansoni protein kinase 0.0121 0.0282 0.0627
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.007 0.0142 0.0347
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0145 0.0297
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0181 0.0444 0.323
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0058 0.0112 0.0109
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0155 0.0373 0.0929
Loa Loa (eye worm) hypothetical protein 0.0072 0.0148 0.0326
Loa Loa (eye worm) patched family protein 0.0027 0.0028 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0293 0.1223
Plasmodium falciparum importin beta, putative 0.0028 0.003 0.0201
Echinococcus granulosus histone deacetylase 6 0.0043 0.0071 0.0171
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0072 0.0148 0.1033
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0048 0.0084 0.0593
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0029 0.0033 0.0106
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0282 0.0627
Loa Loa (eye worm) hypothetical protein 0.0327 0.0839 0.1854
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0245 0.0617 0.1646
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Leishmania major proteasome beta 2 subunit, putative 0.0038 0.0058 0.0241
Schistosoma mansoni histone deacetylase 4 5 0.0043 0.0071 0.0157
Plasmodium vivax unspecified product 0.0125 0.0293 0.2124
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0282 0.0627
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0029 0.0033 0.0082
Echinococcus granulosus geminin 0.0179 0.0439 0.1087
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0048 0.0084 0.035
Schistosoma mansoni z-protein (S1r protein) 0.0029 0.0031 0.0067
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0037 0.0085
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0072 0.0148 0.0307
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0033 0.0074
Brugia malayi Papain family cysteine protease containing protein 0.0331 0.0851 0.1879
Trypanosoma brucei polo-like protein kinase 0.0218 0.0544 0.2271
Mycobacterium leprae proteasome (beta subunit) PrcB 0.008 0.017 0.0367
Echinococcus granulosus expressed protein 0.0056 0.0106 0.0257
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0051 0.0215
Trypanosoma cruzi DNA damage repair protein, putative 0.0065 0.0129 0.0322
Echinococcus multilocularis cathepsin L 0.0125 0.0293 0.029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0155 0.0373 0.1559
Onchocerca volvulus 0.192 0.5152 1
Onchocerca volvulus 0.0245 0.0617 0.1193
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0287 0.073 0.1412
Trypanosoma cruzi DNA polymerase eta, putative 0.0132 0.0312 0.0778
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Mycobacterium ulcerans 6-phosphofructokinase 0.0187 0.046 0.2426
Schistosoma mansoni cathepsin S (C01 family) 0.0121 0.0282 0.0627
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0048 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0028 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0072 0.0148 0.0576
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0172 0.0315
Schistosoma mansoni hypothetical protein 0.0179 0.0439 0.0979
Schistosoma mansoni rotamase 0.0056 0.0106 0.0234
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0218 0.0544 0.2271
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0038
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0081 0.0172 0.0374
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0048 0.0084 0.035
Trypanosoma cruzi Aminopeptidase M1, putative 0.0037 0.0053 0.0133
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1324 0.3539 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0121 0.0282 0.0914
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0071 0.0145 0.0142
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0033 0.0043 0.0106
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0081 0.0172 0.0719
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0051 0.0128
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0121 0.0282 0.0627
Trypanosoma cruzi cysteine peptidase, putative 0.0367 0.0947 0.2357
Giardia lamblia Cathepsin B precursor 0.0121 0.0282 0.0885
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0051 0.0122
Brugia malayi mbt repeat family protein 0.0036 0.0051 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Trypanosoma cruzi trypanothione reductase, putative 0.0181 0.0444 0.1105
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0051 0.0112
Trichomonas vaginalis DNA polymerase eta, putative 0.0233 0.0584 0.1116
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Echinococcus multilocularis transcription factor Dp 1 0.003 0.0035 0.0033
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0155 0.0373 0.0371
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0148 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Giardia lamblia Thioredoxin reductase 0.0048 0.0084 0.024
Plasmodium vivax 6-phosphofructokinase, putative 0.005 0.009 0.0641
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0048 0.0084 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0331 0.0851 0.1635
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0049 0.0076
Echinococcus multilocularis dna polymerase kappa 0.0233 0.0584 0.0582
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0033 0.0043 0.0077
Schistosoma mansoni alpha-glucosidase 0.0137 0.0325 0.0723
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0215 0.0536 0.1413
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0059
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0037 0.0034
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0062 0.0121 0.0868
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0027
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Echinococcus multilocularis histone deacetylase 7 0.0043 0.0071 0.0069
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0125 0.0293 0.0652
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0548 0.1437 0.6002
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Leishmania major cathepsin L-like protease 0.0331 0.0851 0.3553
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0037 0.0053 0.0051
Echinococcus granulosus death domain containing protein 0.0031 0.0037 0.0085
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0209 0.052 0.1147
Trypanosoma brucei DNA polymerase kappa, putative 0.015 0.036 0.1504
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0145 0.0297
Loa Loa (eye worm) hypothetical protein 0.1305 0.3487 0.771
Trypanosoma brucei DNA polymerase IV, putative 0.0227 0.0568 0.2373
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0048 0.0084 0.0192
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Echinococcus granulosus cathepsin l1 0.0327 0.0839 0.2084
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0028 0.0025
Trichomonas vaginalis antibiotic synthetase, putative 0.0072 0.0148 0.0269
Echinococcus granulosus cathepsin b 0.1501 0.4017 1
Loa Loa (eye worm) Csnk2b protein 0.0033 0.0043 0.0092
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.005 0.009 0.0641
Leishmania major 4-coumarate:coa ligase-like protein 0.0245 0.0617 0.2578
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0121 0.0282 0.2041
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.008 0.017 0.0422
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Schistosoma mansoni hypothetical protein 0.0186 0.0458 0.1021
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0052 0.0094 0.0229
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0052 0.0094 0.0092
Brugia malayi Casein kinase II, alpha chain 0.0121 0.0282 0.0621
Entamoeba histolytica hypothetical protein 0.0226 0.0567 0.184
Plasmodium vivax casein kinase II beta chain, putative 0.0033 0.0043 0.029
Trypanosoma cruzi polo-like protein kinase, putative 0.0218 0.0544 0.1353
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0293 0.0729
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0148 0.0307
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.0023 0.0016 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Trichomonas vaginalis phosphofructokinase, putative 0.0187 0.046 0.0875
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Echinococcus granulosus jumonji domain containing protein 0.0036 0.0052 0.0123
Schistosoma mansoni lozenge 0.0059 0.0113 0.025
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0057 0.0054
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Schistosoma mansoni histone deacetylase 4 5 0.0043 0.0071 0.0157
Plasmodium falciparum serine repeat antigen 3 0.0121 0.0282 0.2041
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1191 0.3179 0.8971
Schistosoma mansoni disulfide oxidoreductase 0.0048 0.0084 0.0185
Loa Loa (eye worm) hypothetical protein 0.0093 0.0205 0.0451
Schistosoma mansoni 6-phosphofructokinase 0.0187 0.046 0.1025
Plasmodium vivax patched family protein, putative 0.0027 0.0028 0.0181
Onchocerca volvulus Cathepsin L homolog 0.0331 0.0851 0.1646
Loa Loa (eye worm) hypothetical protein 0.01 0.0224 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0121 0.0282 0.0528
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0055 0.0102 0.0255
Brugia malayi ImpB/MucB/SamB family protein 0.0277 0.0703 0.1552
Toxoplasma gondii preprocathepsin c precursor, putative 0.0121 0.0282 0.1959
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0048 0.0084 0.0122
Brugia malayi T-complex protein 1, beta subunit 0.0029 0.0033 0.0071
Brugia malayi SET domain containing protein 0.0027 0.0026 0.0055
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0121 0.0282 0.0621
Echinococcus multilocularis histone deacetylase 6 0.0043 0.0071 0.0069
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0024 0.0152
Onchocerca volvulus 0.0027 0.0028 0.0048
Onchocerca volvulus 0.0027 0.0028 0.0048
Loa Loa (eye worm) hypothetical protein 0.0277 0.0703 0.1552
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Echinococcus granulosus GA binding protein alpha chain 0.0109 0.0248 0.0612
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0245 0.0617 0.1646
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.0129 0.054
Onchocerca volvulus 0.0071 0.0145 0.0276
Loa Loa (eye worm) hypothetical protein 0.0237 0.0595 0.1314
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0187 0.046 0.1196
Schistosoma mansoni DNA helicase recq1 0.0029 0.0033 0.0071
Plasmodium falciparum glutathione reductase 0.0181 0.0444 0.323
Trypanosoma cruzi NADH dehydrogenase, putative 0.0048 0.0084 0.0209
Echinococcus multilocularis expressed conserved protein 0.0423 0.1099 0.1097
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0029 0.0031 0.0067
Toxoplasma gondii ABC1 family protein 0.0071 0.0145 0.101
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0074 0.0154 0.0322
Brugia malayi cathepsin Z-like cysteine proteinase 0.0121 0.0282 0.0621
Giardia lamblia Cathepsin B precursor 0.0121 0.0282 0.0885
Plasmodium falciparum cysteine proteinase falcipain 1 0.0125 0.0293 0.2124
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0003 0.0007
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0059 0.0113 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0197 0.0438
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0175 0.0427 0.0824
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0052 0.0094 0.0209
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0048 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0038
Brugia malayi cathepsin Z-like cysteine proteinase 0.0121 0.0282 0.0621
Toxoplasma gondii hypothetical protein 0.0027 0.0028 0.0193
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0033 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0048 0.0084 0.0209
Echinococcus multilocularis Protein lozenge 0.0059 0.0113 0.011
Plasmodium falciparum casein kinase II beta chain 0.0033 0.0043 0.029
Onchocerca volvulus 0.0027 0.0028 0.0048
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0037 0.0053 0.0133
Echinococcus multilocularis polycomb protein SCMH1 0.0036 0.0051 0.0049
Echinococcus granulosus GPCR family 2 0.007 0.0142 0.0347
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0247 0.0461
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0028 0.0069
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0062 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Loa Loa (eye worm) hypothetical protein 0.0286 0.0727 0.1606
Leishmania major hypothetical protein, conserved 0.0048 0.0084 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0245 0.0617 0.3361
Brugia malayi beta-lactamase family protein 0.0071 0.0145 0.0319
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) hypothetical protein 0.0193 0.0477 0.1053
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0215 0.0537 0.1331
Entamoeba histolytica cysteine proteinase, putative 0.0125 0.0293 0.0951
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0037 0.0053 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.0125 0.0293 0.0951
Brugia malayi Myosin head containing protein 0.0027 0.0028 0.0059
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0048 0.0084 0.0583
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0062 0.0121 0.0845
Giardia lamblia Cathepsin B precursor 0.0121 0.0282 0.0885
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0121 0.0282 0.0528
Onchocerca volvulus 0.0058 0.0111 0.0211
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0133 0.0314 0.0692
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0048 0.0084 0.0183
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0038 0.0058 0.0055
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0062 0.0121 0.0269
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Schistosoma mansoni hypothetical protein 0.0226 0.0567 0.1264
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0064 0.0062
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Plasmodium vivax SET domain protein, putative 0.0246 0.0619 0.4514
Entamoeba histolytica cysteine proteinase, putative 0.0125 0.0293 0.0951
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0028 0.0063
Leishmania major hypothetical protein, conserved 0.0071 0.0145 0.0606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0051 0.0112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Loa Loa (eye worm) ctsf protein 0.0331 0.0851 0.1879
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0048 0.0084 0.0081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0197 0.0434
Plasmodium vivax 6-phosphofructokinase, putative 0.005 0.009 0.0641
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0281 0.0626
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0289 0.0642
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0048 0.0084 0.0202
Echinococcus granulosus dna polymerase kappa 0.0233 0.0584 0.1449
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0048 0.0084 0.0209
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0037 0.0053 0.0084
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Schistosoma mansoni hypothetical protein 0.1216 0.3245 0.7248
Brugia malayi hypothetical protein 0.0469 0.1222 0.2702
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Echinococcus multilocularis expressed protein 0.0056 0.0106 0.0103
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0125 0.0293 0.0652
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Brugia malayi prolyl oligopeptidase family protein 0.0059 0.0113 0.0247
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0145 0.0556
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0177 0.1272
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0121 0.0282 0.2041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0107 0.0234
Loa Loa (eye worm) hypothetical protein 0.0183 0.0449 0.0992
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0049 0.0076
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0028 0.0182
Loa Loa (eye worm) hypothetical protein 0.0245 0.0617 0.1363
Giardia lamblia Proteasome subunit beta type 2 0.0038 0.0058 0.0155
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0051 0.116
Plasmodium falciparum serine repeat antigen 9 0.0121 0.0282 0.2041
Loa Loa (eye worm) hypothetical protein 0.0143 0.0341 0.0752
Trypanosoma brucei Aminopeptidase M1, putative 0.0037 0.0053 0.0223
Plasmodium vivax importin-beta 2, putative 0.0028 0.003 0.0201
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0247 0.0461
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0048 0.0084 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0001
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0121 0.0282 0.0621
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Echinococcus multilocularis regulator of G protein signaling 7 0.0029 0.0031 0.0029
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Plasmodium falciparum histone deacetylase, putative 0.0043 0.0071 0.05
Echinococcus granulosus expressed conserved protein 0.0423 0.1099 0.2733
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Brugia malayi MH2 domain containing protein 0.0234 0.0586 0.1294
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0181 0.0444 0.1854
Onchocerca volvulus Protein patched homolog 0.0027 0.0028 0.0048
Schistosoma mansoni DNA helicase recq5 0.0029 0.0033 0.0071
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0033 0.0228
Giardia lamblia TCP-1 chaperonin subunit beta 0.0029 0.0033 0.0074
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0048 0.0084 0.0081
Echinococcus granulosus intermediate filament protein 0.0033 0.0042 0.0098
Brugia malayi AMP-binding enzyme family protein 0.0245 0.0617 0.1363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0037 0.0053 0.0127
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0003 0.0004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0385 0.0382
Brugia malayi Histone deacetylase family protein 0.0043 0.0071 0.0155
Entamoeba histolytica hypothetical protein 0.0121 0.0282 0.0914
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0331 0.0851 0.6211
Onchocerca volvulus Alhambra homolog 0.0026 0.0024 0.0042
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0029 0.0033 0.003
Schistosoma mansoni lamin 0.0033 0.0042 0.0091
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0157 0.0377 0.0934
Schistosoma mansoni hypothetical protein 0.0037 0.0054 0.0117
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0124 0.0289 0.0286
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0048 0.0084 0.0271
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0054 0.0127
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Schistosoma mansoni sulfide quinone reductase 0.0048 0.0084 0.0185
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0548 0.1437 0.3208
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0048 0.0084 0.0122
Trypanosoma brucei unspecified product 0.0227 0.0568 0.2373
Brugia malayi cathepsin L-like cysteine proteinase 0.0121 0.0282 0.0621
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Trypanosoma brucei DNA polymerase IV, putative 0.0233 0.0584 0.244
Loa Loa (eye worm) hypothetical protein 0.0287 0.073 0.1612
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) runx1 0.0059 0.0113 0.0248
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Toxoplasma gondii cathepsin CPC2 0.0121 0.0282 0.1959
Trypanosoma cruzi trypanothione reductase, putative 0.0522 0.1368 0.3405
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0028 0.006
Toxoplasma gondii 6-phosphofructokinase 0.005 0.009 0.0629
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0155 0.0373 0.1183
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.001 0.0008
Loa Loa (eye worm) patched family protein 0.0027 0.0028 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0058 0.0112 0.0272
Brugia malayi glutathione reductase 0.0522 0.1368 0.3023
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0041 0.0065 0.0141
Mycobacterium ulcerans hypothetical protein 0.0475 0.1239 0.7058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Echinococcus granulosus tumor protein p63 0.0634 0.167 0.4153
Entamoeba histolytica disulphide oxidoreductase, putative 0.0048 0.0084 0.0271
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0901 0.2394 1
Schistosoma mansoni ets-related 0.033 0.0848 0.1891
Mycobacterium tuberculosis Probable dehydrogenase 0.1191 0.3179 0.8971
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0059
Trypanosoma cruzi 20S proteasome subunit 0.0038 0.0058 0.0143
Mycobacterium ulcerans acyl-CoA synthetase 0.0245 0.0617 0.3361
Brugia malayi hypothetical protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0145 0.0319
Chlamydia trachomatis thioredoxin reductase 0.0048 0.0084 0.0548
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1501 0.4017 0.8973
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0183 0.0449 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0155 0.0373 0.0831
Schistosoma mansoni ran 0.0021 0.001 0.002
Brugia malayi 6-phosphofructokinase 0.0187 0.046 0.1015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0051 0.0128
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0155 0.0373 0.1559
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0564 0.148 0.4113
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0072 0.0148 0.037
Brugia malayi proteasome subunit beta type 2 0.0038 0.0058 0.0125
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.004 0.0063 0.0066
Echinococcus granulosus histone deacetylase 6 0.0043 0.0071 0.0171
Brugia malayi Cathepsin L-like precursor 0.0327 0.0839 0.1854
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.004 0.0063 0.0436
Loa Loa (eye worm) hypothetical protein 0.0072 0.0148 0.0326
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0074 0.0154 0.0338
Entamoeba histolytica thioredoxin reductase, putative 0.0048 0.0084 0.0271
Echinococcus granulosus cathepsin L cysteine proteinase 0.0331 0.0851 0.2113
Brugia malayi hypothetical protein 0.0027 0.0028 0.0059
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0048 0.0084 0.0081
Brugia malayi hypothetical protein 0.0037 0.0053 0.0116
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0127 0.0297 0.0739
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0059
Echinococcus granulosus Niemann Pick C1 protein 0.0644 0.1697 0.4221
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.007 0.0117
Toxoplasma gondii hypothetical protein 0.0145 0.0347 0.2417
Brugia malayi hypothetical protein 0.0027 0.0028 0.0059
Leishmania major cathepsin L-like protease 0.0331 0.0851 0.3553
Loa Loa (eye worm) hypothetical protein 0.0245 0.0617 0.1363
Trypanosoma brucei DNA damage repair protein, putative 0.0065 0.0129 0.054
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0048 0.0084 0.0192
Schistosoma mansoni survival motor neuron protein 0.0058 0.0111 0.0246
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0145 0.0606
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0268 0.0596
Trypanosoma cruzi casein kinase II, putative 0.0121 0.0282 0.0701
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0033 0.0071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Toxoplasma gondii melibiase subfamily protein 0.0124 0.0289 0.2009
Brugia malayi hypothetical protein 0.0053 0.0098 0.0214
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.0798 0.1763
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.004 0.0063 0.0061
Trypanosoma brucei DNA polymerase eta, putative 0.0277 0.0703 0.2935
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0049 0.0107
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0028 0.0116
Loa Loa (eye worm) hypothetical protein 0.1305 0.3487 0.771
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0155 0.0373 0.0923
Mycobacterium tuberculosis Conserved protein 0.0071 0.0145 0.0297
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Giardia lamblia Casein kinase II beta chain 0.0033 0.0043 0.0106
Loa Loa (eye worm) hypothetical protein 0.045 0.1173 0.2594
Loa Loa (eye worm) hypothetical protein 0.007 0.0142 0.0312
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0181 0.0444 0.1854
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0181 0.0444 0.1854
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0129 0.0322
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.008
Plasmodium vivax vivapain-1 0.0125 0.0293 0.2124
Trypanosoma cruzi cysteine proteinase, putative 0.0125 0.0293 0.0729
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0037 0.0066
Brugia malayi serine/threonine-protein kinase plk-2 0.0218 0.0544 0.12
Trypanosoma brucei trypanothione reductase 0.0522 0.1368 0.5714
Mycobacterium ulcerans glutamate synthase subunit beta 0.0048 0.0084 0.0192
Trichomonas vaginalis hypothetical protein 0.0105 0.0238 0.0443
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0037 0.0053 0.0223
Schistosoma mansoni hypothetical protein 0.007 0.0142 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0127 0.0297 0.0739
Toxoplasma gondii cathepsin CPC1 0.0121 0.0282 0.1959
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0121 0.0282 0.2041
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Giardia lamblia Glutamate synthase 0.0048 0.0084 0.024
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0037 0.0053 0.0223
Onchocerca volvulus 0.0072 0.0148 0.0283
Brugia malayi Fli-1 protein 0.033 0.0848 0.1873
Toxoplasma gondii patched family protein 0.0027 0.0028 0.0193
Loa Loa (eye worm) cysteine protease 0.0331 0.0851 0.1879
Loa Loa (eye worm) phosphofructokinase 0.0187 0.046 0.1015
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0125 0.0293 0.055
Schistosoma mansoni glutaminase 0.0658 0.1734 0.3872
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0059 0.0113 0.0471
Onchocerca volvulus 0.0331 0.0851 0.1646
Loa Loa (eye worm) hypothetical protein 0.0514 0.1345 0.2973
Loa Loa (eye worm) fli-1 protein 0.033 0.0848 0.1873
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0245 0.0617 0.1646
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0059 0.0113 0.0471
Toxoplasma gondii phosphofructokinase PFKII 0.005 0.009 0.0629
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.007 0.0142 0.0312
Mycobacterium ulcerans hypothetical protein 0.0065 0.0129 0.0463
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0024 0.0018 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Brugia malayi beta-lactamase family protein 0.0071 0.0145 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0051 0.008
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.1176 0.3245
Echinococcus granulosus snurportin 1 0.0302 0.0771 0.1915
Echinococcus multilocularis histone deacetylase 6 0.0043 0.0071 0.0069
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0081 0.0172 0.0428
Trichomonas vaginalis esterase, putative 0.0071 0.0145 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0839 0.1613
Onchocerca volvulus Cathepsin L homolog 0.0121 0.0282 0.0541
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0215 0.0536 0.2237
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.005 0.009 0.072
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Loa Loa (eye worm) latrophilin receptor protein 2 0.007 0.0142 0.0312
Echinococcus granulosus Dipeptidyl peptidase 9 0.0059 0.0113 0.0275
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.008 0.017 0.0367
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0145 0.0322
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1191 0.3179 0.8971
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0145 0.0297
Schistosoma mansoni hypothetical protein 0.007 0.0142 0.0315
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0059 0.0113 0.0281
Echinococcus multilocularis ubiquitin specific protease 41 0.0155 0.0373 0.0371
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0037 0.0053 0.0051
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0121 0.0282 0.0627
Mycobacterium ulcerans hypothetical protein 0.0048 0.0084 0.0192
Leishmania major DNA polymerase eta, putative 0.0277 0.0703 0.2935
Onchocerca volvulus 0.0331 0.0851 0.1646
Echinococcus granulosus Protein patched homolog 1 0.0193 0.0477 0.1182
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0037 0.0034
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0048 0.0084 0.0593
Trypanosoma brucei NADH dehydrogenase 0.0048 0.0084 0.035
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0245 0.0617 0.3361
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0129 0.0322
Loa Loa (eye worm) hypothetical protein 0.0064 0.0126 0.0277
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0145 0.0319
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0048 0.0084 0.0593
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0072 0.0148 0.1033
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.001 0.007
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.007 0.0117
Loa Loa (eye worm) pigment dispersing factor receptor c 0.022 0.0549 0.1212
Onchocerca volvulus 0.0071 0.0145 0.0276
Brugia malayi prolyl oligopeptidase family protein 0.0175 0.0427 0.0942
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0067
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0145 0.0297
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0048 0.0084 0.0593
Brugia malayi Inositol-1 0.0036 0.0051 0.0112
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0048 0.0084 0.0122
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0038 0.0058 0.0092
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.001 0.0053
Entamoeba histolytica phosphofructokinase, putative 0.0187 0.046 0.1493
Echinococcus granulosus importin subunit beta 1 0.0028 0.003 0.0069
Plasmodium vivax hypothetical protein, conserved 0.0021 0.001 0.005
Leishmania major pantothenate kinase subunit, putative 0.0026 0.0025 0.0104
Loa Loa (eye worm) hypothetical protein 0.0043 0.0071 0.0155
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0056 0.0106 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Schistosoma mansoni tsg101-related 0.0179 0.0439 0.0979
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0037 0.0053 0.0223
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0059 0.0113 0.0281
Brugia malayi intermediate filament protein 0.0033 0.0042 0.0091
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0385 0.0382
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Brugia malayi Histone deacetylase family protein 0.0043 0.0071 0.0155
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0019 0.0018
Leishmania major hypothetical protein, conserved 0.0082 0.0177 0.0737
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0148 0.0307
Schistosoma mansoni alpha glucosidase 0.0035 0.0049 0.0108
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0048 0.0084 0.0183
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0064 0.0153
Brugia malayi Thioredoxin reductase 0.0522 0.1368 0.3023
Brugia malayi T-complex protein 1, beta subunit 0.0029 0.0033 0.0071
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0011
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Echinococcus multilocularis thioredoxin glutathione reductase 0.0527 0.1381 0.1379
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.008 0.017 0.0373
Brugia malayi Peptidase family M1 containing protein 0.0037 0.0053 0.0116
Schistosoma mansoni cpg binding protein 0.0199 0.0494 0.1101
Entamoeba histolytica recQ family helicase, putative 0.0032 0.004 0.0131
Echinococcus granulosus transcription factor Dp 1 0.003 0.0035 0.0081
Brugia malayi RNA, U transporter 1 0.008 0.0172 0.0377
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0177 0.0439
Toxoplasma gondii exonuclease III APE 0.0081 0.0172 0.1197
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0072 0.0148 0.1067
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0282 0.0627
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Giardia lamblia Proteasome subunit beta type 1 0.0062 0.0121 0.0363
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0054 0.0051
Brugia malayi follicle stimulating hormone receptor 0.0233 0.0585 0.1291
Schistosoma mansoni myelin transcription factor 1 myt1 0.0041 0.0065 0.0142
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0049 0.0107
Onchocerca volvulus 0.0331 0.0851 0.1646
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0048 0.0084 0.1888
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0033 0.0075
Leishmania major trypanothione reductase 0.0522 0.1368 0.5714
Loa Loa (eye worm) glutaminase 0.0658 0.1734 0.3834
Loa Loa (eye worm) MBCTL1 0.0041 0.0065 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0072 0.0148 0.0576
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0033 0.0071
Trypanosoma cruzi DNA damage repair protein, putative 0.0065 0.0129 0.0322
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0124 0.0289 0.0713
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0038
Entamoeba histolytica phosphofructokinase, putative 0.0187 0.046 0.1493
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0148 0.0326
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.005 0.009 0.0641
Loa Loa (eye worm) hypothetical protein 0.1501 0.4017 0.8883
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0621
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0522 0.1368 0.3792
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0035 0.0049 0.0047
Schistosoma mansoni hypothetical protein 0.0058 0.0111 0.0246
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0331 0.0851 0.1635
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0062 0.0121 0.0393
Schistosoma mansoni inositol monophosphatase 0.0036 0.0051 0.0113
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0038 0.0058 0.0241
Trypanosoma cruzi aminopeptidase, putative 0.0037 0.0053 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0145 0.1042
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0052 0.0094 0.0207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.007
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0145 0.0263
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0048 0.0084 0.0143
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0121 0.0282 0.0621
Brugia malayi Bromodomain containing protein 0.0029 0.0031 0.0067
Onchocerca volvulus 0.0092 0.0203 0.0389
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0065 0.0129 0.09
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0071 0.0177
Toxoplasma gondii thioredoxin reductase 0.0522 0.1368 0.9519
Plasmodium vivax proteasome subunit beta type-5, putative 0.008 0.017 0.1221
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0038 0.0058 0.0143
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0133 0.0314 0.0692
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0187 0.046 0.1196
Loa Loa (eye worm) oxidoreductase 0.0072 0.0148 0.0326
Onchocerca volvulus Cathepsin F homolog 0.0331 0.0851 0.1646
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0197 0.0438
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0037 0.0053 0.0127
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Plasmodium falciparum serine repeat antigen 8 0.0121 0.0282 0.2041
Schistosoma mansoni cathepsin C 0.0121 0.0282 0.0627
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0048 0.0084 0.0583
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0052 0.0094 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Echinococcus multilocularis sterol regulatory element binding protein 0.0193 0.0477 0.0475
Trypanosoma brucei DNA polymerase IV, putative 0.0233 0.0584 0.244
Brugia malayi CHE-14 protein 0.0193 0.0477 0.1053
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0059
Schistosoma mansoni inositol monophosphatase 0.0036 0.0051 0.0113
Plasmodium vivax unspecified product 0.0121 0.0282 0.2042
Toxoplasma gondii peptidylprolyl isomerase 0.0055 0.0102 0.0712
Brugia malayi F/Y-rich N-terminus family protein 0.008 0.0171 0.0377
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0187 0.046 0.1921
Echinococcus multilocularis cpg binding protein 0.0213 0.053 0.0528
Giardia lamblia Encystation-specific protease 0.0121 0.0282 0.0885
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Echinococcus multilocularis protein patched 0.0193 0.0477 0.0475
Echinococcus granulosus lamin dm0 0.0033 0.0042 0.0098
Brugia malayi Niemann-Pick C1 protein precursor 0.045 0.1173 0.2594
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.001 0.0042
Schistosoma mansoni myst-related protein 0.0026 0.0023 0.0049
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.003 0.0127
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0155 0.0373 0.1211
Brugia malayi beta-lactamase 0.0071 0.0145 0.0319
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.022 0.0549 0.1212
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0033 0.0043 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0019 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0145 0.0263
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0028 0.006
Onchocerca volvulus 0.0027 0.0028 0.0048
Schistosoma mansoni DNA polymerase eta 0.0277 0.0703 0.1567
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0155 0.0373 0.0706
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0029 0.0033 0.0219
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0385 0.0953
Schistosoma mansoni ap endonuclease 0.0081 0.0172 0.0382
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0111
Leishmania major hypothetical protein, conserved 0.0069 0.014 0.0586
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0155 0.0373 0.0371
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0037 0.0053 0.0127
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0062 0.0121 0.0507
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0331 0.0851 0.0848
Toxoplasma gondii ck2 beta subunit 0.0033 0.0043 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0072 0.0148 0.0576
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Onchocerca volvulus 0.0331 0.0851 0.1646
Plasmodium falciparum phd finger protein, putative 0.0026 0.0024 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.0187 0.046 0.0875
Giardia lamblia Cathepsin B precursor 0.0548 0.1437 0.465
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0187 0.046 0.1317
Onchocerca volvulus 0.0331 0.0851 0.1646
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0508 0.0968
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0427 0.1109 0.4631
Brugia malayi hypothetical protein 0.0226 0.0567 0.1251
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Leishmania major cysteine peptidase A (CPA) 0.0331 0.0851 0.3553
Brugia malayi mbt repeat family protein 0.0036 0.0051 0.0111
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0043 0.0137
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0048 0.0084 0.0183
Trypanosoma brucei proteasome subunit beta type-5, putative 0.008 0.017 0.0708
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.01 0.0224 0.0726
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0049 0.0076
Entamoeba histolytica cysteine protease, putative 0.0331 0.0851 0.2763
Onchocerca volvulus 0.0048 0.0084 0.0157
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0172 0.1239
Mycobacterium ulcerans acetyl-CoA synthetase 0.0072 0.0148 0.0576
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Loa Loa (eye worm) hypothetical protein 0.0071 0.0145 0.0319
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0072 0.0148 0.0307
Entamoeba histolytica hypothetical protein 0.0036 0.0051 0.0166
Schistosoma mansoni hypothetical protein 0.0026 0.0024 0.0052
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0187 0.046 0.1145
Loa Loa (eye worm) T-complex protein 1 0.0029 0.0033 0.0071
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.007 0.0142 0.0139
Echinococcus multilocularis histone deacetylase 0.0043 0.0071 0.0069
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0049 0.0047
Brugia malayi N-terminal motif family protein 0.0287 0.073 0.1612
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0135 0.0299
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.001 0.0053
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.004 0.0101
Toxoplasma gondii NADPH-glutathione reductase 0.0181 0.0444 0.3088
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0059
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Giardia lamblia Cysteine protease 0.0121 0.0282 0.0885
Echinococcus granulosus dnaJ subfamily B 0.1216 0.3245 0.8077
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0028 0.0025
Trypanosoma brucei Aminopeptidase M1, putative 0.0037 0.0053 0.0223
Mycobacterium ulcerans NADH dehydrogenase 0.0048 0.0084 0.0192
Onchocerca volvulus 0.0093 0.0205 0.0392
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1854
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0081 0.0172 0.0428
Brugia malayi fibroinase precursor 0.0121 0.0282 0.0621
Leishmania major ATP-dependent phosphofructokinase 0.0187 0.046 0.1921
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0214
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0111 0.0244
Loa Loa (eye worm) thioredoxin reductase 0.0522 0.1368 0.3023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0197 0.0485
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1191 0.3179 0.8971
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0156 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Giardia lamblia Cathepsin B precursor 0.0548 0.1437 0.465
Trypanosoma cruzi DNA polymerase eta, putative 0.0277 0.0703 0.1749
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0038 0.0058 0.0186
Trypanosoma cruzi ISWI complex protein 0.0021 0.001 0.0026
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0181 0.0444 0.2331
Plasmodium falciparum serine repeat antigen 1 0.0121 0.0282 0.2041
Onchocerca volvulus 0.0072 0.0148 0.0283
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0181 0.0444 1
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0048 0.0084 0.0583
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0051 0.0166
Plasmodium falciparum casein kinase 2, alpha subunit 0.0121 0.0282 0.2042
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0036 0.0051 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Entamoeba histolytica hypothetical protein 0.0036 0.0051 0.0166
Schistosoma mansoni ap endonuclease 0.0081 0.0172 0.0382
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0282 0.0621
Brugia malayi glutaminase DH11.1 0.0658 0.1734 0.3834
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0048 0.0084 0.0122
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0049 0.0086 0.0189
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0233 0.0585 0.1291
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Schistosoma mansoni hypothetical protein 0.007 0.0142 0.0315
Leishmania major cathepsin L-like protease 0.0331 0.0851 0.3553
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0264 0.0668 0.149
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Plasmodium falciparum proteasome subunit beta type-5 0.008 0.017 0.1221
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0145 0.0361
Leishmania major importin beta-1 subunit, putative 0.0023 0.0016 0.0066
Loa Loa (eye worm) RecQ helicase 0.0043 0.007 0.0153
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Echinococcus multilocularis muscleblind protein 0.1305 0.3487 0.3485
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0181 0.0444 0.1854
Echinococcus multilocularis GA binding protein alpha chain 0.0109 0.0248 0.0246
Echinococcus multilocularis cathepsin b 0.1501 0.4017 0.4015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Schistosoma mansoni cathepsin F (C01 family) 0.0327 0.0839 0.1873
Echinococcus granulosus casein kinase ii subunit beta 0.0033 0.0043 0.01
Schistosoma mansoni cellular tumor antigen P53 0.0093 0.0205 0.0455
Entamoeba histolytica cysteine proteinase, putative 0.0331 0.0851 0.2763
Brugia malayi latrophilin 2 splice variant baaae 0.015 0.0361 0.0795
Onchocerca volvulus 0.0037 0.0053 0.0098
Leishmania major 4-coumarate:coa ligase-like protein 0.0245 0.0617 0.2578
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0127 0.0297 0.0739
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1154 0.3078 1
Treponema pallidum NADH oxidase 0.0181 0.0444 0.1264
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0183 0.0449 0.0992
Echinococcus multilocularis lysine specific demethylase 5A 0.0103 0.0232 0.0229
Echinococcus multilocularis dna polymerase eta 0.0277 0.0703 0.07
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0033 0.0043 0.0178
Echinococcus multilocularis SAM and MBT domain containing protein 0.0036 0.0051 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0173 0.0422 0.1089
Brugia malayi PHD-finger family protein 0.0038 0.0056 0.0121
Echinococcus multilocularis bloom syndrome protein 0.0043 0.007 0.0068
Toxoplasma gondii histone deacetylase HDAC1 0.0043 0.0071 0.0496
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0181 0.0444 0.1105
Leishmania major acetyl-CoA synthetase, putative 0.0072 0.0148 0.062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Plasmodium vivax proteasome subunit beta type-1, putative 0.0062 0.0121 0.0868
Leishmania major histone deacetylase, putative 0.0043 0.0071 0.0298
Echinococcus granulosus cpg binding protein 0.0213 0.053 0.1314
Schistosoma mansoni hypothetical protein 0.0235 0.0591 0.1317
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0155 0.0373 0.0831
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.0771 0.1704
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.007 0.0142 0.0139
Toxoplasma gondii proteasome subunit beta type, putative 0.008 0.017 0.118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0209 0.052 0.1158
Schistosoma mansoni regulator of G protein signaling 0.0029 0.0031 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0072 0.0148 0.0576
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0042 0.0091
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.01 0.0218
Mycobacterium ulcerans aminopeptidase N PepN 0.0037 0.0053 0.0011
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0033 0.0071
Echinococcus granulosus L aminoadipate semialdehyde 0.0143 0.0341 0.0842
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0072 0.0148 0.0576
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Echinococcus granulosus histone lysine methyltransferase setb 0.0264 0.0668 0.1657
Echinococcus multilocularis snurportin 1 0.0302 0.0771 0.0769
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0048 0.0084 0.0081
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0172 0.1239
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0033 0.0228
Trichomonas vaginalis mercuric reductase, putative 0.0181 0.0444 0.0843
Leishmania major acetyl-CoA synthetase, putative 0.0072 0.0148 0.062
Brugia malayi Death domain containing protein 0.0031 0.0037 0.0079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Plasmodium vivax JmjC domain containing protein 0.0027 0.0028 0.0182
Treponema pallidum fructose-bisphosphate aldolase 0.1154 0.3078 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0139
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0155 0.0373 0.0923
Schistosoma mansoni hypothetical protein 0.0022 0.0013 0.0026
Schistosoma mansoni alpha-glucosidase 0.0137 0.0325 0.0723
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0048 0.0084 0.0271
Schistosoma mansoni cathepsin F (C01 family) 0.0331 0.0851 0.1898
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0076 0.0128
Onchocerca volvulus 0.0027 0.0028 0.0048
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.004 0.0063 0.0437
Toxoplasma gondii t-complex protein beta subunit 0.0029 0.0033 0.0229
Mycobacterium tuberculosis Conserved protein 0.0071 0.0145 0.0297
Schistosoma mansoni tsg101-related 0.0179 0.0439 0.0979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0037 0.0053 0.0051
Mycobacterium ulcerans hypothetical protein 0.0245 0.0617 0.3361
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0076 0.0128
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0004 0.0007
Leishmania major NADH dehydrogenase, putative 0.0048 0.0084 0.035
Trypanosoma cruzi polo-like protein kinase, putative 0.0218 0.0544 0.1353
Echinococcus multilocularis nuclear factor of activated T cells 5 0.03 0.0767 0.0765
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Schistosoma mansoni hypothetical protein 0.0048 0.0084 0.0185
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0003 0.0001
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0121 0.0282 0.2041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1501 0.4017 0.8973
Trypanosoma brucei ISWI complex protein 0.0021 0.001 0.0044
Brugia malayi phosphofructokinase 0.0187 0.046 0.1015
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0289 0.0642
Entamoeba histolytica cysteine proteinase, putative 0.0331 0.0851 0.2763
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0071 0.0145 0.0354
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0033 0.0075
Brugia malayi regulator of G-protein signaling egl-10 0.0029 0.0031 0.0067
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0072 0.0148 0.0307
Trypanosoma brucei histone deacetylase 4 0.0043 0.0071 0.0298
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0226 0.0567 0.0564
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0018 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0082 0.0177 0.0393
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0121 0.0282 0.2041
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0289 0.0642
Mycobacterium ulcerans acyl-CoA synthetase 0.0245 0.0617 0.3361
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0538 0.1026
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0038 0.0058 0.0092
Plasmodium falciparum glutathione reductase 0.0522 0.1368 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0121 0.0282 0.0621
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1191 0.3179 0.8971
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0132 0.0312 0.2174
Schistosoma mansoni 6-phosphofructokinase 0.0187 0.046 0.1025
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0121 0.0281 0.0687
Trypanosoma cruzi cysteine proteinase, putative 0.0125 0.0293 0.0729
Loa Loa (eye worm) hypothetical protein 0.0183 0.0449 0.0992
Echinococcus granulosus zinc finger protein 0.0032 0.0041 0.0095
Leishmania major hypothetical protein, conserved 0.0048 0.0084 0.035
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0051 0.0049
Trichomonas vaginalis rotamase, putative 0.0055 0.0102 0.0179
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0049 0.0076
Giardia lamblia Cysteine protease 0.0121 0.0282 0.0885
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0091
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0385 0.0849
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0037 0.0079
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0048 0.0084 0.1888
Trypanosoma brucei cysteine peptidase C (CPC) 0.0548 0.1437 0.6002
Echinococcus granulosus proteasome prosome macropain 0.008 0.017 0.0416
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0246 0.0619 0.4308
Giardia lamblia Cathepsin L precursor 0.0121 0.0282 0.0885
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0076 0.0128
Trypanosoma brucei chrX additional, unordered contigs 0.0065 0.0129 0.054
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0016 0.0039
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0055 0.0102 0.0427
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0564 0.148 0.849
Toxoplasma gondii patched family protein 0.0027 0.0028 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0121 0.0281 0.0695
Onchocerca volvulus 0.0469 0.1222 0.2369
Giardia lamblia Cathepsin B precursor 0.0548 0.1437 0.465
Schistosoma mansoni acetyl-CoA synthetase 0.0072 0.0148 0.0329
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0197 0.0485
Echinococcus granulosus sterol regulatory element binding protein 0.0193 0.0477 0.1182
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0048 0.0084 0.0143
Trypanosoma cruzi cysteine protease, putative 0.0125 0.0293 0.0729
Onchocerca volvulus 0.0121 0.0282 0.0541
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0245 0.0617 0.1646
Onchocerca volvulus 0.0143 0.0341 0.0656
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0218 0.0544 0.12
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0145 0.0322
Brugia malayi AMP-binding enzyme family protein 0.0245 0.0617 0.1363
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Echinococcus multilocularis histone deacetylase 6 0.0043 0.0071 0.0069
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Toxoplasma gondii cathepsin B 0.0548 0.1437 1
Plasmodium falciparum zinc finger protein, putative 0.0026 0.0023 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0246 0.0619 0.1381
Loa Loa (eye worm) histone methyltransferase 0.0071 0.0145 0.0318
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Giardia lamblia Hypothetical protein 0.0121 0.0282 0.0885
Brugia malayi jmjC domain containing protein 0.0027 0.0028 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.0839 0.1613
Entamoeba histolytica phosphofructokinase, putative 0.0187 0.046 0.1493
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0331 0.0851 0.6211
Giardia lamblia Cysteine protease 0.0121 0.0282 0.0885
Leishmania major cathepsin L-like protease 0.0367 0.0947 0.3955
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0181 0.0444 0.9854
Echinococcus multilocularis cathepsin b 0.1501 0.4017 0.4015
Brugia malayi hypothetical protein 0.0027 0.0028 0.0059
Mycobacterium tuberculosis Probable reductase 0.1191 0.3179 0.8971
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0432 0.1123 0.2507
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0081 0.0172 0.0422
Mycobacterium ulcerans hypothetical protein 0.0071 0.0145 0.0556
Brugia malayi Patched related family protein 4 0.0027 0.0028 0.0059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0475 0.1239 0.3424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0145 0.0355
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.0798 0.1763
Toxoplasma gondii Alpha-galactosidase 0.0018 0.0001 0.0008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0049 0.016
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0193 0.0477 0.1053
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0049 0.016
Echinococcus granulosus expressed protein 0.0282 0.0717 0.1779
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0071 0.0177
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0042 0.0091
Loa Loa (eye worm) hypothetical protein 0.0043 0.007 0.0154
Echinococcus multilocularis importin subunit beta 1 0.0028 0.003 0.0028
Leishmania major cathepsin L-like protease 0.0331 0.0851 0.3553
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0264 0.0668 0.1475
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0051 0.0358
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0072 0.0148 0.0307
Loa Loa (eye worm) hypothetical protein 0.0327 0.0839 0.1854
Onchocerca volvulus 0.0027 0.0028 0.0048
Trypanosoma cruzi NADH dehydrogenase, putative 0.0048 0.0084 0.0209
Trichomonas vaginalis set domain proteins, putative 0.192 0.5151 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.022 0.0549 0.1212
Entamoeba histolytica cysteine proteinase, putative 0.0125 0.0293 0.0951
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0121 0.0282 0.2042
Echinococcus granulosus bloom syndrome protein 0.0043 0.007 0.0168
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.001 0.0025
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0072 0.0148 0.062
Entamoeba histolytica cysteine protease, putative 0.0121 0.0282 0.0914
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0074 0.0154 0.0341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Echinococcus multilocularis dnaJ subfamily B 0.1216 0.3245 0.3243
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0048 0.0084 0.0192
Trichomonas vaginalis phosphofructokinase, putative 0.005 0.009 0.0156
Echinococcus granulosus aminopeptidase N 0.0037 0.0053 0.0127
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Loa Loa (eye worm) hypothetical protein 0.0089 0.0194 0.0427
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0072 0.0148 0.0146
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0148 0.0576
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.001 0.002
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0049 0.0117
Onchocerca volvulus 0.0327 0.0839 0.1625
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.004 0.0063 0.0437
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0048 0.0084 0.035
Loa Loa (eye worm) patched family protein 0.0027 0.0028 0.0059
Toxoplasma gondii selenide, water dikinase 0.0048 0.0084 0.0583
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0121 0.0282 0.2041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0293 0.1223
Entamoeba histolytica protein kinase domain containing protein 0.0121 0.0282 0.0914
Brugia malayi jmjC domain containing protein 0.0157 0.0377 0.0833
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0058 0.0112 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0282 0.0528
Echinococcus granulosus polycomb protein SCMH1 0.0036 0.0051 0.0121
Leishmania major cathepsin L-like protease 0.0331 0.0851 0.3553
Plasmodium vivax proteasome subunit beta type-2, putative 0.0038 0.0058 0.0401
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0363 0.0936 0.2329
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0181 0.0444 0.1105
Giardia lamblia Cathepsin L-like protease 0.0121 0.0282 0.0885
Echinococcus granulosus histone deacetylase 0.0043 0.0071 0.0171
Trichomonas vaginalis glutamate synthase, putative 0.0048 0.0084 0.0143
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0181 0.0444 0.323
Treponema pallidum exodeoxyribonuclease (exoA) 0.0081 0.0172 0.0363
Mycobacterium ulcerans ferredoxin reductase 0.0048 0.0084 0.0192
Echinococcus multilocularis geminin 0.0179 0.0439 0.0437
Schistosoma mansoni terminal deoxycytidyl transferase 0.0209 0.052 0.1158
Brugia malayi 6-phosphofructokinase 0.0187 0.046 0.1015
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0071 0.0145 0.1012
Schistosoma mansoni hypothetical protein 0.0186 0.0458 0.1021
Echinococcus multilocularis cathepsin L cysteine protease 0.0331 0.0851 0.0848
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0246 0.0619 0.0617
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Echinococcus granulosus regulator of G protein signaling 7 0.0029 0.0031 0.0071
Schistosoma mansoni cathepsin F (C01 family) 0.0331 0.0851 0.1898
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0071 0.0157
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0036 0.0051 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Echinococcus multilocularis proteasome (prosome, macropain) 0.008 0.017 0.0167
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0147 0.035 0.1138
Mycobacterium ulcerans lipase LipD 0.0071 0.0145 0.0556
Echinococcus granulosus 6 phosphofructokinase 0.0187 0.046 0.1139
Brugia malayi Bromodomain containing protein 0.0041 0.0063 0.0138
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0145 0.0297
Leishmania major DNA polymerase kappa, putative 0.0215 0.0536 0.2237
Loa Loa (eye worm) hypothetical protein 0.022 0.0549 0.1212
Trypanosoma brucei histone deacetylase, putative 0.0043 0.0071 0.0298
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.008 0.017 0.031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0177 0.039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0075 0.0164
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0048 0.0084 0.024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0197 0.0434
Loa Loa (eye worm) hypothetical protein 0.0082 0.0177 0.0388
Entamoeba histolytica serine/threonine protein kinase, putative 0.0218 0.0544 0.1765
Brugia malayi Uncoordinated protein 44 0.0031 0.0037 0.0079
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0084 0.0209
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0181 0.0444 0.323
Schistosoma mansoni hypothetical protein 0.0031 0.0037 0.008
Loa Loa (eye worm) glutathione reductase 0.0522 0.1368 0.3023
Echinococcus multilocularis expressed protein 0.0282 0.0717 0.0714
Leishmania major cathepsin L-like protease 0.0367 0.0947 0.3955
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Echinococcus granulosus cathepsin L 0.0125 0.0293 0.0723
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0028 0.0059
Toxoplasma gondii histone lysine methyltransferase SET1 0.0389 0.1008 0.7012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0072 0.0148 0.037
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0048 0.0084 0.1888
Echinococcus granulosus cathepsin l cysteine peptidase 0.0331 0.0851 0.2113
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0194 0.081
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0148 0.0307
Plasmodium vivax histone deacetylase 2, putative 0.0043 0.0071 0.05
Entamoeba histolytica hypothetical protein 0.0036 0.0051 0.0166
Trypanosoma brucei DNA polymerase kappa, putative 0.015 0.036 0.1504
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0043 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0049 0.0123
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.001 0.005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0289 0.0642
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0048 0.0084 0.0192
Giardia lamblia Cysteine protease 0.0121 0.0282 0.0885
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0072 0.0148 0.0576
Leishmania major T-complex protein 1, beta subunit, putative 0.0029 0.0033 0.0137
Entamoeba histolytica Ran family GTPase 0.0021 0.001 0.0032
Onchocerca volvulus 0.0033 0.0042 0.0076
Onchocerca volvulus 0.0027 0.0026 0.0044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0155 0.0373 0.0929
Trypanosoma cruzi major cysteine proteinase, putative 0.0157 0.0378 0.094
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.003 0.0211
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0183 0.0449 0.2365
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0129 0.0282
Onchocerca volvulus 0.0033 0.0042 0.0076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0282 0.0627
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0215 0.0537 0.0535
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0181 0.0444 0.1105
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Toxoplasma gondii phosphofructokinase domain-containing protein 0.005 0.009 0.0629
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0062 0.0121 0.0302
Loa Loa (eye worm) beta-lactamase 0.0071 0.0145 0.0319
Echinococcus multilocularis histone acetyltransferase MYST2 0.0041 0.0065 0.0062
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0264 0.0668 0.0665
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0022 0.0154
Onchocerca volvulus 0.0246 0.0619 0.1197
Trypanosoma cruzi DNA polymerase kappa, putative 0.0233 0.0584 0.1454
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Plasmodium vivax serine-repeat antigen (SERA) 0.0121 0.0282 0.2041
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0028 0.0194
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0057 0.0135
Schistosoma mansoni bromodomain containing protein 0.0078 0.0166 0.0368
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0072 0.0148 0.0307
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0145 0.0263
Brugia malayi Bromodomain containing protein 0.0091 0.0199 0.0439
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0048 0.0084 0.0143
Giardia lamblia Cathepsin L-like protease 0.0121 0.0282 0.0885
Brugia malayi PHD-finger family protein 0.0022 0.0013 0.0027
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Loa Loa (eye worm) jmjC domain-containing protein 0.0116 0.0268 0.059
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0051 0.0215
Trichomonas vaginalis glutathione reductase, putative 0.0181 0.0444 0.0843
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0154 0.0151
Echinococcus multilocularis 6 phosphofructokinase 0.0187 0.046 0.0457
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0181 0.0444 0.1151
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0029 0.0033 0.0137
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0218 0.0544 0.1348
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0051 0.008
Echinococcus multilocularis cathepsin L 0.0121 0.0282 0.0279
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0003 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0084 0.0209
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0125 0.0293 0.0729
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0469 0.1222 0.2702
Giardia lamblia DINP protein human, muc B family 0.0215 0.0536 0.1713
Echinococcus multilocularis protein dispatched 1 0.0221 0.0551 0.0549
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Echinococcus granulosus cathepsin L cysteine protease 0.0125 0.0293 0.0723
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0043 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0233 0.0584 0.1454
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0175 0.0427 0.0424
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.001 0.0019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0181 0.0444 0.2331
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0154 0.0377
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0121 0.0282 0.0914
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0331 0.0851 0.1635
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Schistosoma mansoni hypothetical protein 0.0302 0.0771 0.1721
Echinococcus granulosus peregrin 0.0029 0.0031 0.0071
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.004 0.0059
Brugia malayi protein C24B5.3 0.0027 0.0028 0.0059
Brugia malayi Proteasome A-type and B-type family protein 0.008 0.017 0.0373
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0148 0.0307
Echinococcus granulosus casein kinase ii subunit alpha 0.0121 0.0282 0.0695
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0544 0.1038
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0038 0.0058 0.0137
Echinococcus granulosus lysine specific demethylase 5A 0.0116 0.0268 0.0661
Loa Loa (eye worm) PHD-finger family protein 0.0026 0.0024 0.0052
Toxoplasma gondii PHD-finger domain-containing protein 0.0026 0.0024 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0148 0.0576
Plasmodium falciparum thioredoxin reductase 0.0181 0.0444 0.323
Loa Loa (eye worm) hypothetical protein 0.015 0.0361 0.0795
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0127 0.0297 0.124
Onchocerca volvulus 0.0037 0.0053 0.0098
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0033 0.0043 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0125 0.0293 0.055
Brugia malayi Latrophilin receptor protein 2 0.007 0.0142 0.0312
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0038 0.0058 0.0401
Echinococcus multilocularis cysteine protease 0.0331 0.0851 0.0848
Brugia malayi cathepsin L precursor 0.0121 0.0282 0.0621
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Echinococcus granulosus histone deacetylase 6 0.0043 0.0071 0.0171
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1324 0.3539 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0143 0.0341 0.0338
Treponema pallidum thioredoxin reductase (trxB) 0.0048 0.0084 0.007
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0048 0.0084 0.0143
Trypanosoma brucei DNA damage repair protein, putative 0.0065 0.0129 0.054
Loa Loa (eye worm) aminopeptidase N 0.0037 0.0053 0.0116
Brugia malayi Patched family protein 0.0027 0.0028 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0233 0.0584 0.244
Schistosoma mansoni glutamate synthase 0.0048 0.0084 0.0185
Loa Loa (eye worm) CXXC zinc finger family protein 0.0199 0.0494 0.109
Echinococcus multilocularis Niemann Pick C1 protein 0.045 0.1173 0.1171
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0028 0.0069
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0177 0.1229
Echinococcus multilocularis GPCR, family 2 0.007 0.0142 0.0139
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0081 0.0172 0.3876
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.004 0.0169
Toxoplasma gondii patched family protein 0.0027 0.0028 0.0193
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0081 0.0172 0.0528
Brugia malayi Pre-SET motif family protein 0.1687 0.4522 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0282 0.0528
Loa Loa (eye worm) 6-phosphofructokinase 0.0187 0.046 0.1015
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0081 0.0172 0.0378
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0177 0.0737
Brugia malayi Ets-domain containing protein 0.0109 0.0248 0.0547
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.003 0.0127
Onchocerca volvulus 0.0027 0.0028 0.0048
Echinococcus granulosus mixed lineage leukemia protein mll 0.0058 0.0112 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0798 0.1533
Plasmodium falciparum serine repeat antigen 2 0.0121 0.0282 0.2041
Brugia malayi Cathepsin L-like precursor 0.0331 0.0851 0.1879
Echinococcus multilocularis cathepsin L cysteine protease 0.0331 0.0851 0.0848
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0059 0.0113 0.0785
Echinococcus multilocularis zinc finger protein 0.0032 0.0041 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0051 0.008
Brugia malayi hypothetical protein 0.0082 0.0177 0.0388
Schistosoma mansoni lamin 0.0033 0.0042 0.0091
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0072 0.0148 0.0307
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0181 0.0444 0.1854
Plasmodium falciparum DNA repair protein REV1, putative 0.0065 0.0129 0.0926
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0282 0.0621
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0281 0.0626
Onchocerca volvulus Protein patched homolog 0.0027 0.0028 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0282 0.0528
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Entamoeba histolytica cysteine protease, putative 0.0125 0.0293 0.0951
Echinococcus multilocularis peregrin 0.0029 0.0031 0.0029
Brugia malayi Protein kinase domain containing protein 0.0032 0.0041 0.0089
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0145 0.0556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0331 0.0851 0.1635
Schistosoma mansoni hypothetical protein 0.0179 0.0439 0.0979
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0018 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0282 0.0627
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0173 0.0422 0.1089
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0063 0.0261
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0059
Echinococcus granulosus cathepsin l1 0.0331 0.0851 0.2113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.0947 0.3955
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0121 0.0282 0.0627
Onchocerca volvulus 0.0514 0.1345 0.2607
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0037 0.0053 0.0051
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0226 0.0567 0.1405
Loa Loa (eye worm) prolyl oligopeptidase 0.0175 0.0427 0.0942
Trypanosoma brucei DNA polymerase kappa, putative 0.015 0.036 0.1504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1154 0.3078 0.5968
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0331 0.0851 0.1879
Brugia malayi Ets-domain containing protein 0.0109 0.0248 0.0547
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0181 0.0444 0.2331
Schistosoma mansoni gabp alpha 0.0109 0.0248 0.0552

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 10 % Inhibitory activity against monoamine oxidase A (MAO A) from rat brain using a radiometric procedure with [3H]- serotonin at 1 microM ChEMBL. 8027990
Inhibition (binding) = 10 % Inhibitory activity against monoamine oxidase A (MAO A) from rat brain using a radiometric procedure with [3H]- serotonin at 1 microM ChEMBL. 8027990
Inhibition (binding) = 12 % Inhibitory activity against monoamine oxidase B (MAO B) from rat brain using a radiometric procedure with [14C]- phenethylamine at 1 uM ChEMBL. 8027990
Inhibition (binding) = 12 % Inhibitory activity against monoamine oxidase B (MAO B) from rat brain using a radiometric procedure with [14C]- phenethylamine at 1 uM ChEMBL. 8027990
Potency (functional) 0.1636 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate. (Class of assay: confirmatory) [Related pubchem assays: 1472, 1467 ] ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 8.1961 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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