Detailed information for compound 1266198

Basic information

Technical information
  • TDR Targets ID: 1266198
  • Name: ethyl-hexadecyl-dimethylazanium bromide
  • MW: 378.474 | Formula: C20H44BrN
  • H donors: 0 H acceptors: 0 LogP: 9.37 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC[N+](CC)(C)C.[Br-]
  • InChi: 1S/C20H44N.BrH/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(3,4)6-2;/h5-20H2,1-4H3;1H/q+1;/p-1
  • InChiKey: VUFOSBDICLTFMS-UHFFFAOYSA-M  


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Synonyms

  • ethyl-hexadecyl-dimethyl-ammonium bromide
  • ethyl-hexadecyl-dimethylammonium bromide
  • cetyl-ethyl-dimethyl-ammonium bromide
  • ethyl-hexadecyl-dimethyl-azanium bromide
  • 124-03-8
  • CDA
  • 1-Hexadecanaminium, N-ethyl-N,N-dimethyl-, bromide
  • AI3-12210
  • Alkenyl dimethyl ethyl ammonium bromide
  • Ammonium, ethylhexadecyldimethyl-, bromide
  • Ammonyx DME
  • Bretol
  • Caswell No. 165E
  • Cetethyldimonium bromide
  • Cetyl dimethyl ethyl ammonium bromide
  • Cetylcide
  • Cetyldimethylethylammonium bromide
  • Cetylethyldimethylammonium bromide
  • Dimethylethylhexadecylammonium bromide
  • EINECS 204-672-8
  • EPA Pesticide Chemical Code 069156
  • ETHYLHEXADECYLDIMETHYLAMMONIUM BROMIDE
  • Ethyl cetab
  • Ethyl hexadecyl dimethyl ammonium bromide
  • Hexadecyldimethylethylammonium bromide
  • Hexadecylethyldimethylammonium bromide
  • N-Ethyl-N,N-dimethyl-1-hexadecanaminium bromide
  • NSC 8494
  • Quaternium 17
  • Radiol germicidal solution
  • NSC8494
  • C5335_SIGMA
  • Quaternium-17
  • WLN: 16K2 & 1 & 1 & Q & E
  • C0636_SIGMA

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAD52 homolog (S. cerevisiae) Starlite/ChEMBL No references
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. Starlite/ChEMBL No references
Plasmodium falciparum heat shock protein 90, putative Starlite/ChEMBL No references
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB Starlite/ChEMBL No references
Human immunodeficiency virus 1 Aberrant vpr protein Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Streptococcus pyogenes serotype M1 Streptokinase A Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens arginine vasopressin receptor 1A Starlite/ChEMBL No references
Homo sapiens androgen receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei gambiense nascent polypeptide associated complex alpha subunit, putative Get druggable targets OG5_127333 All targets in OG5_127333
Giardia lamblia DNA repair protein RAD52 Get druggable targets OG5_130806 All targets in OG5_130806
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. Get druggable targets OG5_130095 All targets in OG5_130095
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium knowlesi basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Neospora caninum hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Plasmodium falciparum basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Babesia bovis heat shock protein 90 Get druggable targets OG5_144951 All targets in OG5_144951
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) ICD-1 protein Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni Replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. Get druggable targets OG5_130095 All targets in OG5_130095
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Chlamydia trachomatis replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans similar to S. cerevisiae RAD52 (YML032C) dsDNA break repair annealing factor Get druggable targets OG5_130806 All targets in OG5_130806
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii Hsp90 domain-containing protein Get druggable targets OG5_144951 All targets in OG5_144951
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Babesia bovis NAC domain containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii heat shock protein 83 Get druggable targets OG5_144951 All targets in OG5_144951
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica DNA repair and recombination protein RAD52, putative Get druggable targets OG5_130806 All targets in OG5_130806
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax heat shock protein, putative Get druggable targets OG5_144951 All targets in OG5_144951
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans similar to S. cerevisiae RAD52 (YML032C) dsDNA break repair annealing factor Get druggable targets OG5_130806 All targets in OG5_130806
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii basic transcription factor 3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium vivax basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum replicative DNA helicase (dnaB) Get druggable targets OG5_131890 All targets in OG5_131890
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii NAC domain-containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi beta-NAC-like protein Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans replicative DNA helicase DnaB Get druggable targets OG5_131890 All targets in OG5_131890
Wolbachia endosymbiont of Brugia malayi recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum ko:K01527 nascent polypeptide-associated complex subunit beta, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB Get druggable targets OG5_131890 All targets in OG5_131890
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum BTF domain, basal transcription factor Get druggable targets OG5_127333 All targets in OG5_127333
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Theileria parva heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Chlamydia trachomatis recombinase RecA Get druggable targets OG5_130095 All targets in OG5_130095
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Cryptosporidium hominis NAC domain protein Get druggable targets OG5_127333 All targets in OG5_127333
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi acetyltransferase, GNAT family protein 0.029 0.0683 0.1551
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0123 0.0274 0.027
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Leishmania major cathepsin L-like protease 0.0073 0.0153 0.0979
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0019 0.0124
Schistosoma mansoni amine GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.1545 0.3759 0.8533
Echinococcus multilocularis amyloid beta A4 protein 0.0139 0.0314 0.0614
Trypanosoma cruzi oligopeptidase b 0.0013 0.0005 0.0034
Schistosoma mansoni peroxidasin 0.007 0.0145 0.0283
Echinococcus granulosus neuropeptide s receptor 0.0184 0.0423 0.0828
Plasmodium falciparum glutathione reductase 0.0019 0.0019 0.0397
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Schistosoma mansoni glutaminase 0.0271 0.0637 0.1245
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.007 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0013 0.0005 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Brugia malayi hypothetical protein 0.007 0.0145 0.0329
Echinococcus granulosus 7tm_1 domain containing protein 0.0184 0.0423 0.0828
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0013 0.0006 0.0012
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Brugia malayi nuclear receptor NHR-88 0.1545 0.3759 0.8533
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0009 0.006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0083 0.0188
Onchocerca volvulus 0.0087 0.0187 0.0486
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0009 0.006
Echinococcus multilocularis RUN 0.0021 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0009 0.006
Schistosoma mansoni loxhd1 0.0021 0.0024 0.0047
Brugia malayi Melatonin receptor type 1A 0.0184 0.0423 0.0961
Brugia malayi Nuclear hormone receptor family member nhr-31 0.1545 0.3759 0.8533
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0009 0.0025
Brugia malayi hypothetical protein 0.0134 0.0301 0.0683
Chlamydia trachomatis cytosol aminopeptidase 0.0123 0.0274 0.2318
Echinococcus granulosus peregrin 0.0043 0.0079 0.0154
Loa Loa (eye worm) fibroinase 0.0019 0.002 0.0047
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0729 0.1759 0.3438
Echinococcus multilocularis somatostatin receptor 0.0184 0.0423 0.0828
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0163 0.1028
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.043 0.1026 0.2006
Leishmania major cysteine peptidase A (CPA) 0.0019 0.002 0.0131
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0031 0.005 0.1026
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0005
Echinococcus granulosus 7TM GPCR rhodopsin 0.0184 0.0423 0.0828
Onchocerca volvulus 0.0184 0.0423 0.1115
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0109 0.0696
Schistosoma mansoni rab6-interacting 0.0021 0.0024 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0096 0.0582
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0006 0.0012
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Leishmania major hypothetical protein, conserved 0.0015 0.001 0.0067
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0467 0.1117 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0032 0.0051 0.01
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0009 0.0025
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0096 0.0614
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0103 0.0225 0.1441
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.002 0.004
Echinococcus granulosus aldo keto reductase 0.0649 0.1564 0.3056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0013 0.0005 0.0034
Onchocerca volvulus 0.0184 0.0423 0.1115
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0184 0.0423 0.0828
Echinococcus granulosus voltage dependent calcium channel 0.0092 0.0199 0.0389
Echinococcus multilocularis aldo keto reductase 0.0649 0.1564 0.3056
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.012 0.0235
Schistosoma mansoni heat shock protein 0.0037 0.0063 0.0124
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0013 0.0006 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0077 0.0475
Brugia malayi Serotonin receptor 0.0184 0.0423 0.0961
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0123 0.0274 0.1751
Loa Loa (eye worm) oxidoreductase 0.0649 0.1564 0.355
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0083 0.0162
Brugia malayi heat shock protein 90 0.0055 0.0109 0.0247
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.0225 0.1427
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0041 0.0094
Echinococcus multilocularis neuropeptide receptor A26 0.0184 0.0423 0.0828
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0262 0.0616 0.3942
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0013 0.0006 0.0012
Brugia malayi AMP-binding enzyme family protein 0.005 0.0096 0.0218
Brugia malayi SRC-1 0.004 0.007 0.0159
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.002 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0115 0.0733
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0184 0.0423 0.0961
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0649 0.1564 0.355
Echinococcus multilocularis two pore calcium channel protein 2 0.0013 0.0006 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1545 0.3759 0.7346
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0052 0.107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0729 0.1759 0.3438
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0019 0.0397
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Schistosoma mansoni hypothetical protein 0.0022 0.0028 0.0055
Echinococcus granulosus voltage dependent calcium channel 0.043 0.1026 0.2006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.1545 0.3759 0.7346
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0729 0.1759 0.3438
Brugia malayi FAD binding domain containing protein 0.0019 0.0021 0.0047
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Echinococcus multilocularis isocitrate dehydrogenase 0.0036 0.0061 0.0119
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0009 0.0005
Brugia malayi nuclear receptor NHR-67 0.0729 0.1759 0.3993
Onchocerca volvulus 0.0057 0.0114 0.0291
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0103 0.0225 0.0512
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0056 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-40 0.1545 0.3759 0.8533
Toxoplasma gondii aldo-keto reductase 0.0188 0.0434 0.2775
Brugia malayi Thioredoxin reductase 0.0054 0.0106 0.0241
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0056 0.011
Mycobacterium leprae Probable lipase LipE 0.0156 0.0356 0.105
Echinococcus multilocularis g protein coupled receptor 0.0184 0.0423 0.0828
Echinococcus granulosus nuclear receptor nhr 48 0.0729 0.1759 0.3438
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.043 0.1026 0.2006
Onchocerca volvulus Cathepsin L homolog 0.0019 0.002 0.0042
Brugia malayi PHD-finger family protein 0.0034 0.0056 0.0126
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.043 0.1026 0.2006
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.0276 0.0272
Schistosoma mansoni transient receptor potential channel 0.0013 0.0006 0.0012
Echinococcus granulosus potassium large conductance calcium activated 0.0013 0.0006 0.0012
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Onchocerca volvulus 0.0156 0.0356 0.0935
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0184 0.0423 0.0828
Schistosoma mansoni cpg binding protein 0.0037 0.0064 0.0125
Brugia malayi Steroid receptor seven-up type 2 0.1545 0.3759 0.8533
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi cathepsin L-like precursor 0.0013 0.0005 0.0011
Brugia malayi Flap endonuclease-1 0.003 0.0046 0.0105
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0096 0.0614
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.007 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Echinococcus multilocularis transient receptor potential gamma protein 0.0013 0.0006 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0033 0.0214
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0019 0.0021 0.0133
Onchocerca volvulus 0.0184 0.0423 0.1115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0167 0.0383 0.087
Echinococcus multilocularis cysteine protease 0.0019 0.002 0.004
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0009 0.006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0036 0.0061 0.0119
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0005
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0005 0.0018
Schistosoma mansoni RAR-like nuclear receptor 0.1545 0.3759 0.7346
Echinococcus multilocularis cpg binding protein 0.0037 0.0064 0.0125
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0013 0.0005 0.0034
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0024 0.0033 0.0075
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Loa Loa (eye worm) hypothetical protein 0.0486 0.1164 0.2643
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.021 0.041
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0006 0.0012
Echinococcus granulosus neuropeptide receptor A26 0.0184 0.0423 0.0828
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0009 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0816 0.1973 0.4479
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.0487 0.3115
Echinococcus granulosus cathepsin l1 0.0019 0.002 0.004
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0019 0.0015
Schistosoma mansoni transient receptor potential channel 0.0013 0.0006 0.0012
Brugia malayi hypothetical protein 0.0013 0.0006 0.0014
Onchocerca volvulus Peroxidase homolog 0.007 0.0145 0.0373
Mycobacterium tuberculosis Conserved protein 0.0156 0.0356 0.0352
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0123 0.0274 0.0804
Schistosoma mansoni dynamin 0.0026 0.0036 0.0071
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Schistosoma mansoni dynamin 0.0028 0.0041 0.0081
Leishmania major cytochrome p450-like protein 0.0034 0.0056 0.0357
Trypanosoma cruzi aldo/keto reductase, putative 0.0649 0.1564 1
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0124 0.0278 0.0631
Echinococcus granulosus dro:myosuppressin receptor 0.0184 0.0423 0.0828
Echinococcus granulosus geminin 0.0695 0.1675 0.3274
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus multilocularis calcium activated potassium channel 0.0015 0.0009 0.0017
Echinococcus multilocularis muscleblind protein 1 0.0486 0.1164 0.2276
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0153 0.0979
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0013 0.0006 0.0012
Schistosoma mansoni leucine aminopeptidase 0.0024 0.0033 0.0065
Brugia malayi Latrophilin receptor protein 2 0.0167 0.0383 0.087
Brugia malayi beta-lactamase family protein 0.0156 0.0356 0.0808
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0154 0.0349
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0006 0.0012
Loa Loa (eye worm) blistered cuticle protein 3 0.007 0.0145 0.0329
Leishmania major cytochrome P450 reductase, putative 0.0028 0.0041 0.0264
Echinococcus granulosus calcium activated potassium channel 0.0015 0.0009 0.0017
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0043
Brugia malayi olfactory channel protein osm-9 0.0013 0.0006 0.0014
Loa Loa (eye worm) voltage-gated potassium channel 0.0013 0.0006 0.0014
Schistosoma mansoni cytochrome P450 0.0015 0.001 0.002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0184 0.0423 0.0828
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0649 0.1564 1
Echinococcus granulosus g protein coupled receptor 0.0184 0.0423 0.0828
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1545 0.3759 0.8533
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi GnHR receptor homolog 0.0184 0.0423 0.0961
Brugia malayi Transient-receptor-potential like protein 0.0013 0.0006 0.0014
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0006 0.0012
Echinococcus granulosus allatostatin A receptor 0.0184 0.0423 0.0828
Echinococcus granulosus neuropeptide Y receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0054 0.0105 0.0238
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0006 0.0012
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0005 0.0012
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0006 0.0012
Plasmodium falciparum aldo-keto reductase, putative 0.0188 0.0434 0.891
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.001 0.003
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0001 0.0003
Onchocerca volvulus 0.0649 0.1564 0.4153
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0019 0.0019 0.0388
Brugia malayi jmjC domain containing protein 0.0111 0.0244 0.0555
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0089
Schistosoma mansoni transcription factor btf3 0.0042 0.0077 0.015
Schistosoma mansoni amyloid beta A4 protein related 0.0139 0.0314 0.0614
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0044 0.008 0.0499
Echinococcus granulosus short transient receptor potential channel 6 0.0013 0.0006 0.0012
Loa Loa (eye worm) voltage-gated calcium channel 0.0013 0.0006 0.0014
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.1668 0.406 0.7936
Leishmania major hypothetical protein, unknown function 0.0013 0.0006 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.1545 0.3759 0.8533
Echinococcus granulosus cathepsin l1 0.0013 0.0005 0.001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.002 0.0047
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0184 0.0423 0.0828
Brugia malayi hypothetical protein 0.0042 0.0077 0.0176
Trichomonas vaginalis aldo-keto reductase, putative 0.0188 0.0434 0.2763
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0033 0.0075
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0024 0.0033 0.0075
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0156 0.0356 0.0808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0013 0.0006 0.0012
Loa Loa (eye worm) animal heme peroxidase 0.007 0.0145 0.0329
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0184 0.0423 0.0828
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.001 0.003
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.0309 0.0701
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.1545 0.3759 0.8533
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0005 0.0018
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0123 0.0274 0.562
Mycobacterium ulcerans hypothetical protein 0.0188 0.0434 0.275
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0156 0.0356 0.0808
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.0597 0.1356
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis aldo keto reductase 0.0649 0.1564 0.3056
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0188 0.0434 0.0985
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Echinococcus multilocularis leucyl aminopeptidase 0.0024 0.0033 0.0065
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0005 0.0109
Loa Loa (eye worm) nuclear receptor NHR-67 0.0729 0.1759 0.3993
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0036 0.0061 0.0119
Brugia malayi Dynamin central region family protein 0.0026 0.0036 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0405 0.2576
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0006 0.0012
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0019 0.0116
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0816 0.1973 0.4479
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0096 0.1972
Treponema pallidum recombinase A 0.013 0.0293 0.2603
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0006 0.0012
Trichomonas vaginalis glutaminase, putative 0.0271 0.0637 0.4062
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0131
Plasmodium vivax serine/threonine kinase-1, putative 0.007 0.0144 0.2967
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.0109 0.0689
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.002 0.0421
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0188 0.0434 0.2775
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.012 0.0235
Brugia malayi nuclear receptor RXR 0.0729 0.1759 0.3993
Plasmodium falciparum nitric oxide synthase, putative 0.0031 0.005 0.1026
Echinococcus granulosus ecdysone induced protein 78C 0.1545 0.3759 0.7346
Brugia malayi cation channel family protein 0.0013 0.0006 0.0014
Plasmodium falciparum protein serine/threonine kinase-1 0.007 0.0144 0.2967
Toxoplasma gondii NAC domain-containing protein 0.0042 0.0077 0.0491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0005 0.0014
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0154 0.0349
Schistosoma mansoni nuclear receptor 0.0729 0.1759 0.3438
Echinococcus multilocularis sex peptide receptor 0.0184 0.0423 0.0828
Onchocerca volvulus 0.0019 0.002 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Mycobacterium ulcerans recombinase A 0.013 0.0293 0.1843
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.0309 0.0701
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0024 0.0033 0.0075
Leishmania major hypothetical protein, conserved 0.005 0.0096 0.0614
Onchocerca volvulus 0.0184 0.0423 0.1115
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0729 0.1759 0.4673
Echinococcus granulosus ryanodine receptor 44f 0.0013 0.0006 0.0012
Brugia malayi ion channel NompC 0.0013 0.0006 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0184 0.0423 0.0961
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0149 0.0292
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Leishmania major aldo-keto reductase-like protein 0.0649 0.1564 1
Echinococcus granulosus serotonin receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis tensin 0.0019 0.0019 0.0037
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0467 0.1117 0.7131
Echinococcus multilocularis prolyl endopeptidase 0.0013 0.0005 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0153 0.0979
Onchocerca volvulus 0.0184 0.0423 0.1115
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Schistosoma mansoni steroid hormone receptor ad4bp 0.1545 0.3759 0.7346
Brugia malayi beta-NAC-like protein 0.0042 0.0077 0.0174
Onchocerca volvulus Cathepsin F homolog 0.0019 0.002 0.0042
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Loa Loa (eye worm) hypothetical protein 0.0167 0.0383 0.087
Loa Loa (eye worm) cytochrome P450 0.0015 0.001 0.0023
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0056 0.0109 0.07
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Schistosoma mansoni hypothetical protein 0.0034 0.0056 0.011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0816 0.1973 0.3856
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0006 0.0012
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0019 0.0021 0.0041
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0052 0.0102 0.0651
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0083 0.0162
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0188 0.0434 0.2763
Brugia malayi hypothetical protein 0.0021 0.0024 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.1545 0.3759 0.8533
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0184 0.0423 0.0828
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.0077 0.0491
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.043 0.1026 0.233
Echinococcus multilocularis neuropeptides capa receptor 0.0184 0.0423 0.0828
Echinococcus granulosus tyrosine kinase 0.0036 0.0061 0.0119
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis potassium large conductance calcium activated 0.0013 0.0006 0.0012
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0013 0.0006 0.0014
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0361 0.0857 0.1674
Brugia malayi Protein kinase domain containing protein 0.0103 0.0225 0.0512
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0033 0.0084
Brugia malayi flavodoxin family protein 0.0031 0.005 0.0113
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0061 0.0119
Mycobacterium tuberculosis Probable reductase 0.0124 0.0276 0.0272
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.031 0.0306
Onchocerca volvulus 0.0019 0.002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0047
Onchocerca volvulus 0.0729 0.1759 0.4673
Entamoeba histolytica aldose reductase, putative 0.0649 0.1564 1
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi Dynamin 0.0028 0.0041 0.0094
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.007 0.0137
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0024 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0729 0.1759 0.3438
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0061 0.0119
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.008 0.0183
Toxoplasma gondii PHD-finger domain-containing protein 0.0011 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.1545 0.3759 0.8533
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0109 0.0696
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Leishmania major heat shock protein, putative 0.0037 0.0063 0.0405
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.0186 0.1175
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Echinococcus multilocularis dynamin 1 0.0028 0.0041 0.0081
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0 0.0002
Plasmodium vivax aldehyde reductase, putative 0.0188 0.0434 0.891
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0013 0.0006 0.004
Brugia malayi hypothetical protein 0.0816 0.1973 0.4479
Plasmodium falciparum heat shock protein 90, putative 0.021 0.0487 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0729 0.1759 0.3438
Schistosoma mansoni hypothetical protein 0.0076 0.016 0.0313
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.021 0.041
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0033 0.0129
Onchocerca volvulus 0.0649 0.1564 0.4153
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.007 0.0137
Echinococcus granulosus heat shock protein 90 0.0047 0.0089 0.0174
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0105 0.0205
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0816 0.1973 0.3856
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0106 0.2179
Brugia malayi G-protein coupled receptor 0.0184 0.0423 0.0961
Brugia malayi voltage-dependent calcium channel 0.0013 0.0006 0.0014
Onchocerca volvulus 0.0013 0.0006 0.0004
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Mycobacterium leprae conserved hypothetical protein 0.0156 0.0356 0.105
Echinococcus granulosus aldehyde reductase 0.0461 0.1103 0.2156
Schistosoma mansoni DNA helicase recq1 0.0011 0.0001 0.0002
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0006 0.0012
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0083 0.0162
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.012 0.0735
Mycobacterium ulcerans beta-lactamase 0.0156 0.0356 0.2249
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Schistosoma mansoni neuropeptide receptor 0.0184 0.0423 0.0828
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0046 0.029
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.002 0.0047
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0046 0.0105
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0006 0.0012
Schistosoma mansoni endoplasmin 0.0055 0.0109 0.0213
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0009 0.0018
Schistosoma mansoni biogenic amine receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Loa Loa (eye worm) TYRA-2 protein 0.0184 0.0423 0.0961
Echinococcus granulosus neuropeptide FF receptor 2 0.0184 0.0423 0.0828
Loa Loa (eye worm) ctsf protein 0.0019 0.002 0.0047
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0154 0.0349
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0154 0.03
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0012
Echinococcus multilocularis protein numb 0.0015 0.0009 0.0018
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0383 0.1006
Onchocerca volvulus Cathepsin L homolog 0.0019 0.002 0.0042
Echinococcus granulosus prolyl endopeptidase 0.0013 0.0005 0.0011
Brugia malayi hypothetical protein 0.0032 0.0053 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Onchocerca volvulus Prolyl endopeptidase homolog 0.0013 0.0005 0.0001
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0012 0.0003 0.0054
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0013 0.0005 0.0018
Toxoplasma gondii dynamin gtpase 0.0017 0.0015 0.0095
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0184 0.0423 0.0961
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.0186 0.1175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0184 0.0423 0.1115
Echinococcus multilocularis voltage gated potassium channel subunit 0.0188 0.0434 0.0848
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0019 0.0021 0.0133
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0009 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0009 0.0025
Brugia malayi Muscleblind-like protein 0.0486 0.1164 0.2643
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Schistosoma mansoni tensin-related 0.0019 0.0019 0.0037
Giardia lamblia Kinase, CMGC CLK 0.007 0.0144 0.0917
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0036 0.0061 0.1251
Mycobacterium leprae putative cytochrome p450 0.0015 0.001 0.0014
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0056 0.0358
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0011
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0156 0.0356 0.0696
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.0063 0.0124
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0033 0.0064
Echinococcus multilocularis cysteine protease 0.0019 0.002 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0056 0.0127
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0073 0.0144
Loa Loa (eye worm) hypothetical protein 0.0102 0.0223 0.0506
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.001 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0096 0.0092
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.0113
Loa Loa (eye worm) ICD-1 protein 0.0042 0.0077 0.0174
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0013 0.0006 0.004
Onchocerca volvulus 0.0015 0.0009 0.0012
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0096 0.0582
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0061 0.039
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0012
Brugia malayi glutathione reductase 0.0054 0.0106 0.0241
Loa Loa (eye worm) TK protein kinase 0.0036 0.0061 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-41 0.1545 0.3759 0.8533
Trypanosoma cruzi prolyl endopeptidase 0.0013 0.0005 0.0034
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0014
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0012 0.0003 0.0017
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0044 0.008 0.0183
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0156 0.0356 0.0696
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0009 0.006
Echinococcus multilocularis tumor protein p63 0.0393 0.0935 0.1828
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0013
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0184 0.0423 0.0828
Loa Loa (eye worm) animal heme peroxidase 0.007 0.0145 0.0329
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.002
Echinococcus multilocularis short transient receptor potential channel 6 0.0013 0.0006 0.0012
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0046 0.0297
Loa Loa (eye worm) FAD binding domain-containing protein 0.0019 0.0021 0.0047
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0077 0.0491
Schistosoma mansoni Tr4/Tr2 (homologue) 0.1545 0.3759 0.7346
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.0597 0.1356
Echinococcus granulosus beta LACTamase domain containing family member 0.0156 0.0356 0.0696
Chlamydia trachomatis sulfite reductase 0.0019 0.0021 0.0012
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0009 0.006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1545 0.3759 0.8533
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.001 0.003
Brugia malayi larval opioid receptor 0.0184 0.0423 0.0961
Trichomonas vaginalis aldo/keto reductase, putative 0.0649 0.1564 1
Leishmania major hypothetical protein, conserved 0.0012 0.0003 0.0017
Echinococcus granulosus tachykinin peptides receptor 99D 0.048 0.1149 0.2246
Schistosoma mansoni voltage-gated cation channel 0.043 0.1026 0.2006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0729 0.1759 0.3438
Schistosoma mansoni opsin-like receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis heat shock protein 90 0.0055 0.0109 0.0213
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0106 0.0207
Plasmodium vivax dynamin protein, putative 0.0026 0.0036 0.0747
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.1545 0.3759 0.7346
Brugia malayi G protein-coupled receptor 0.0184 0.0423 0.0961
Schistosoma mansoni cpg binding protein 0.0033 0.0055 0.0107
Brugia malayi beta-lactamase family protein 0.0156 0.0356 0.0808
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Schistosoma mansoni aldo-keto reductase 0.0649 0.1564 0.3056
Brugia malayi Nuclear hormone receptor-like 1 0.1545 0.3759 0.8533
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Echinococcus granulosus neuropeptide receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0151
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.008 0.0515
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0096 0.0614
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0005 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0184 0.0423 0.0828
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.1545 0.3759 0.7346
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Toxoplasma gondii ABC1 family protein 0.0156 0.0356 0.2276
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.0276 0.0272
Brugia malayi Cathepsin L-like precursor 0.0013 0.0005 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0362 0.0859 0.195
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0013 0.0006 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0006 0.004
Loa Loa (eye worm) glutaminase 2 0.0271 0.0637 0.1446
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.0276 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Toxoplasma gondii prolyl endopeptidase 0.0013 0.0005 0.0034
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0101 0.0627
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0006 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.021 0.041
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0109 0.0696
Onchocerca volvulus 0.0649 0.1564 0.4153
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0006 0.0012
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3756 0.9176 0.9176
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus multilocularis allatostatin A receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable oxidoreductase 0.0649 0.1564 0.156
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0021 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0362 0.0859 0.195
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0056 0.115
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0165 0.0378 0.0739
Loa Loa (eye worm) latrophilin receptor protein 2 0.0167 0.0383 0.087
Brugia malayi nuclear receptor NHR-88 0.0729 0.1759 0.3993
Brugia malayi tailless protein 0.0729 0.1759 0.3993
Echinococcus granulosus two pore calcium channel protein 1 0.0013 0.0006 0.0012
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.007 0.0144 0.0924
Brugia malayi NADH-dependent xylose reductase 0.0188 0.0434 0.0985
Onchocerca volvulus 0.0019 0.0021 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Schistosoma mansoni amine GPCR 0.0184 0.0423 0.0828
Toxoplasma gondii cathepsin CPL 0.0019 0.002 0.0131
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0013 0.0006 0.0012
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0013 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0816 0.1973 0.3856
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0114 0.0259
Echinococcus multilocularis leucyl aminopeptidase 0.0024 0.0033 0.0065
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0009 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Schistosoma mansoni hypothetical protein 0.0695 0.1675 0.3274
Brugia malayi cytochrome P450 0.0015 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0012
Onchocerca volvulus 0.1545 0.3759 1
Echinococcus granulosus two pore calcium channel protein 2 0.0013 0.0006 0.0012
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0123 0.0274 0.1751
Onchocerca volvulus 0.0729 0.1759 0.4673
Brugia malayi TAR-binding protein 0.0074 0.0154 0.0349
Echinococcus granulosus g-protein coupled receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.1668 0.406 0.7936
Brugia malayi prolyl oligopeptidase family protein 0.0056 0.0109 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0729 0.1759 0.4673
Trypanosoma cruzi DNA repair protein, putative 0.004 0.0072 0.0458
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0033 0.0075
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0184 0.0423 0.0828
Echinococcus granulosus aldo keto reductase 0.0649 0.1564 0.3056
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0031 0.005 0.0098
Echinococcus multilocularis FTZ F1 alpha 0.1545 0.3759 0.7346
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1809 0.4405 1
Entamoeba histolytica hypothetical protein 0.0076 0.016 0.1008
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0005 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1545 0.3759 0.7346
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1545 0.3759 0.8533
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0123 0.0274 0.1751
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative 0.0026 0.0036 0.0216
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0011
Toxoplasma gondii aldose reductase, putative 0.0649 0.1564 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0425 0.1016 0.2306
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0096 0.0582
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0031 0.005 0.032
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0037 0.0063 0.0389
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.002 0.0131
Echinococcus granulosus alpha 1A adrenergic receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0127
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0649 0.1564 1
Trypanosoma brucei aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0006 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0009 0.0012
Toxoplasma gondii flavodoxin domain-containing protein 0.0016 0.0011 0.0073
Schistosoma mansoni polycystin 1-related 0.0021 0.0024 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.001 0.0006
Onchocerca volvulus 0.0184 0.0423 0.1115
Entamoeba histolytica cysteine protease, putative 0.0019 0.002 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) oxidoreductase 0.0649 0.1564 0.355
Echinococcus granulosus SHC transforming protein 3 0.0019 0.0019 0.0037
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.001 0.003
Brugia malayi Protein kinase domain containing protein 0.007 0.0144 0.0328
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0019 0.0089
Schistosoma mansoni zinc finger protein 0.0729 0.1759 0.3438
Loa Loa (eye worm) hypothetical protein 0.0139 0.0313 0.071
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Plasmodium falciparum endoplasmin, putative 0.004 0.0072 0.1472
Trichomonas vaginalis endoplasmin, putative 0.004 0.0072 0.0442
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Leishmania major GTP-binding protein, putative 0.0026 0.0036 0.0233
Loa Loa (eye worm) endoplasmin 0.0055 0.0109 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0184 0.0423 0.0961
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0096 0.0599
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.0591 0.1341
Echinococcus multilocularis conserved hypothetical protein 0.0013 0.0006 0.0012
Echinococcus multilocularis ryanodine receptor 44f 0.0013 0.0006 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0167 0.0383 0.0749
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0033 0.0076
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0013 0.0005 0.0034
Schistosoma mansoni ryanodine receptor related 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Brugia malayi PHD-finger family protein 0.0015 0.001 0.0022
Schistosoma mansoni hypothetical protein 0.0474 0.1134 0.2217
Schistosoma mansoni Replicative DNA helicase 0.0467 0.1117 0.2182
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0033 0.0687
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.016 0.0313
Schistosoma mansoni coup transcription factor 0.1545 0.3759 0.7346
Entamoeba histolytica protein kinase, putative 0.0103 0.0225 0.1427
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.001 0.0064
Mycobacterium leprae Conserved hypothetical protein 0.1376 0.3344 1
Echinococcus granulosus dnaJ subfamily B 0.0474 0.1134 0.2217
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.007 0.0144 0.0924
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.012 0.0735
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.0077 0.0475
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0187 0.0366
Trichomonas vaginalis aldo/keto reductase, putative 0.0649 0.1564 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0939 0.2275 0.4446
Brugia malayi glutaminase DH11.1 0.0271 0.0637 0.1446
Schistosoma mansoni hypothetical protein 0.0167 0.0383 0.0749
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0131
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Schistosoma mansoni myosin xvIII 0.0184 0.0423 0.0828
Brugia malayi Serine protease Z688.6 precursor 0.0019 0.0021 0.0047
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0024 0.0047
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.007 0.0137
Schistosoma mansoni hypothetical protein 0.0167 0.0383 0.0749
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0012 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0061 0.039
Toxoplasma gondii hypothetical protein 0.0013 0.0006 0.004
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0729 0.1759 0.3438
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.001 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Trichomonas vaginalis esterase, putative 0.0156 0.0356 0.2263
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Brugia malayi Cytochrome P450 family protein 0.0015 0.001 0.0023
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0061 0.039
Onchocerca volvulus Protein ultraspiracle homolog 0.1545 0.3759 1
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0089 0.0571
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0061 0.039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.001 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0005 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Echinococcus granulosus sodium leak channel non selective protein 0.0013 0.0006 0.0012
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0033 0.0668
Loa Loa (eye worm) melatonin receptor type 1A 0.0184 0.0423 0.0961
Echinococcus multilocularis voltage dependent calcium channel 0.043 0.1026 0.2006
Brugia malayi Cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0014
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0096 0.0582
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0012
Echinococcus granulosus fmrfamide receptor 0.0184 0.0423 0.0828
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1545 0.3759 0.8533
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Brugia malayi prolyl oligopeptidase family protein 0.0165 0.0378 0.0859
Brugia malayi putative neuropeptide receptor 0.0184 0.0423 0.0961
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0001 0.0002
Trypanosoma brucei aminopeptidase, putative 0.0024 0.0033 0.0212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.043 0.1026 0.2006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0024 0.0047
Echinococcus granulosus heat shock protein 90 0.0055 0.0109 0.0213
Schistosoma mansoni vesicular amine transporter 0.0013 0.0006 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Plasmodium vivax heat shock protein 90, putative 0.0037 0.0063 0.1301
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0055
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus multilocularis carboxyl terminal PDZ ligand of neuronal nitric 0.0015 0.0009 0.0018
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0063 0.0124
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0013 0.0006 0.0014
Treponema pallidum NADH oxidase 0.0019 0.0019 0.015
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0009 0.0025
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0019 0.0107
Mycobacterium leprae Conserved hypothetical protein 0.0461 0.1103 0.3288
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0096 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0056 0.011
Brugia malayi flavodoxin family protein 0.0012 0.0003 0.0006
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.001 0.0006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0058 0.0114
Trypanosoma brucei dynamin-1-like protein 0.0026 0.0036 0.0233
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.1545 0.3759 0.7346
Brugia malayi cytosol aminopeptidase 0.0024 0.0033 0.0075
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0019 0.0397
Echinococcus multilocularis voltage dependent calcium channel 0.043 0.1026 0.2006
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Brugia malayi hypothetical protein 0.0021 0.0024 0.0055
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Schistosoma mansoni lipoxygenase 0.0021 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Echinococcus multilocularis dro:myosuppressin receptor 0.0184 0.0423 0.0828
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.002 0.0114
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0006 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Brugia malayi Animal haem peroxidase family protein 0.007 0.0145 0.0329
Echinococcus granulosus hypothetical protein 0.0649 0.1564 0.3056
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Onchocerca volvulus 0.0184 0.0423 0.1115
Echinococcus granulosus tar DNA binding protein 0.0074 0.0154 0.03
Brugia malayi Dopamine receptor protein 1 0.0184 0.0423 0.0961
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.001 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0056 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0013 0.0006 0.0014
Onchocerca volvulus 0.0156 0.0356 0.0935
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0009 0.0025
Mycobacterium leprae Possible oxidoreductase 0.0188 0.0434 0.1284
Brugia malayi protein M110.5 0.0015 0.0009 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0156 0.0356 0.0352
Schistosoma mansoni tyrosine kinase 0.004 0.007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0148
Brugia malayi orphan nuclear receptor NR2E1 0.0729 0.1759 0.3993
Schistosoma mansoni hypothetical protein 0.0021 0.0024 0.0047
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0096 0.0582
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.001 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0184 0.0423 0.0828
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.007 0.0137
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0103 0.0225 0.1441
Schistosoma mansoni bromodomain containing protein 0.0072 0.0149 0.0291
Trichomonas vaginalis penicillin-binding protein, putative 0.0156 0.0356 0.2263
Echinococcus multilocularis G-protein coupled receptor, putative 0.0184 0.0423 0.0828
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.001 0.003
Trypanosoma cruzi aldo/keto reductase, putative 0.0188 0.0434 0.2775
Loa Loa (eye worm) G-protein coupled receptor 0.0184 0.0423 0.0961
Mycobacterium ulcerans hypothetical protein 0.005 0.0096 0.0582
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.001 0.0006
Echinococcus multilocularis thyroid hormone receptor alpha 0.1545 0.3759 0.7346
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Schistosoma mansoni transient receptor potential channel 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0019 0.002 0.0042
Brugia malayi hypothetical protein 0.0309 0.0729 0.1656
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Plasmodium falciparum aldehyde reductase, putative 0.0188 0.0434 0.891
Schistosoma mansoni heat shock protein 0.0055 0.0109 0.0213
Loa Loa (eye worm) hypothetical protein 0.0092 0.0199 0.0452
Trypanosoma cruzi p450 reductase, putative 0.0031 0.005 0.032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0006 0.0012
Brugia malayi hypothetical protein 0.0729 0.1759 0.3993
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0203
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0019 0.0021 0.0041
Plasmodium vivax SET domain protein, putative 0.0037 0.0063 0.1301
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.1545 0.3759 0.7346
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0036 0.0061 0.1251
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0187 0.0366
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0044 0.008 0.0515
Echinococcus granulosus somatostatin receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis heat shock protein 90 0.0047 0.0089 0.0174
Echinococcus multilocularis fmrfamide receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0009 0.0005
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0467 0.1117 0.3328
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0012 0.0003 0.0017
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0019 0.0124
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.031 0.0306
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0073 0.0142
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0089 0.0174
Echinococcus granulosus carboxyl terminal PDZ ligand of neuronal nitric 0.0015 0.0009 0.0018
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0009 0.0025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.001 0.0006
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Brugia malayi Cytochrome P450 family protein 0.0015 0.001 0.0023
Echinococcus granulosus peroxidasin 0.007 0.0145 0.0283
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.007 0.0144 0.0924
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0031 0.005 0.032
Echinococcus multilocularis GPCR, family 2 0.0167 0.0383 0.0749
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0043
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0156 0.0356 0.0352
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0529 0.1269 0.2881
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.002 0.0421
Echinococcus granulosus voltage gated potassium channel subunit 0.0188 0.0434 0.0848
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0111 0.0244 0.0477
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.029 0.0683 0.1335
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0033 0.0129
Loa Loa (eye worm) FAD binding domain-containing protein 0.0031 0.005 0.0113
Loa Loa (eye worm) prolyl oligopeptidase 0.0165 0.0378 0.0859
Leishmania major prostaglandin f synthase, putative 0.0649 0.1564 1
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0106 0.0241
Toxoplasma gondii leucyl aminopeptidase LAP 0.0123 0.0274 0.1751
Schistosoma mansoni opsin-like receptor 0.0184 0.0423 0.0828
Plasmodium falciparum peptidase, putative 0.0013 0.0005 0.0111
Schistosoma mansoni thyroid hormone receptor 0.1545 0.3759 0.7346
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.005 0.0096 0.0218
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0729 0.1759 0.3438
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0156 0.0356 0.0696
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0816 0.1973 0.4479
Onchocerca volvulus 0.007 0.0145 0.0373
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0096 0.0582
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0056 0.011
Schistosoma mansoni peroxidasin 0.007 0.0145 0.0283
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0006 0.0012
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0028 0.0055
Schistosoma mansoni opsin-like receptor 0.0184 0.0423 0.0828
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0021 0.0116
Brugia malayi nuclear hormone receptor 0.1545 0.3759 0.8533
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0649 0.1564 1
Trichomonas vaginalis sulfite reductase, putative 0.0031 0.005 0.0303
Schistosoma mansoni histamine h1 receptor 0.0184 0.0423 0.0828
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0106 0.0679
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0123 0.0274 0.1751
Echinococcus granulosus Dipeptidyl peptidase 9 0.0056 0.0109 0.0214
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0014 0.0007 0.0016
Trichomonas vaginalis aldo/keto reductase, putative 0.0649 0.1564 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.001 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0156 0.0356 0.0352
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0001 0.0002
Entamoeba histolytica Flap nuclease, putative 0.003 0.0046 0.0281
Echinococcus multilocularis dynamin 1 protein 0.0026 0.0036 0.0071
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0013 0.0006 0.0014
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.043 0.1026 0.2006
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.001 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0356 0.2263
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.001 0.003
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0044 0.008 0.0157
Echinococcus granulosus tumor protein p63 0.0393 0.0935 0.1828
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0163 0.1036
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.021 0.0476
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.012 0.0116
Leishmania major cathepsin L-like protease 0.0073 0.0153 0.0979
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0184 0.0423 0.0828
Plasmodium falciparum thioredoxin reductase 0.0019 0.0019 0.0397
Loa Loa (eye worm) neuropeptide F receptor 0.0184 0.0423 0.0961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.1668 0.406 0.9218
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0013 0.0006 0.0014
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0013 0.0006 0.0012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0009 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0184 0.0423 0.0828
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0009 0.006
Schistosoma mansoni jumonji domain containing protein 0.0088 0.0189 0.0369
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0009 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.001 0.0064
Brugia malayi hypothetical protein 0.0015 0.0009 0.0021
Trypanosoma cruzi dynamin-1-like protein 0.0026 0.0036 0.0233
Leishmania major hypothetical protein, conserved 0.0013 0.0006 0.004
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0005 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0729 0.1759 0.3438
Trypanosoma cruzi DNA repair protein, putative 0.004 0.0072 0.0458
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.001 0.003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0001 0.0007
Schistosoma mansoni adenoreceptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi follicle stimulating hormone receptor 0.0425 0.1016 0.2306
Onchocerca volvulus Bile acid receptor homolog 0.1545 0.3759 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0649 0.1564 0.355
Echinococcus granulosus dynamin 1 0.0028 0.0041 0.0081
Echinococcus multilocularis flap endonuclease 1 0.003 0.0046 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0184 0.0423 0.0828
Onchocerca volvulus Dual oxidase homolog 0.007 0.0145 0.0373
Loa Loa (eye worm) oxidoreductase 0.0649 0.1564 0.355
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0114 0.0223
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0405 0.2576
Echinococcus multilocularis g protein coupled receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0816 0.1973 0.4479
Giardia lamblia Serine peptidase, putative 0.0019 0.0021 0.0126
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) calcium channel 0.043 0.1026 0.233
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0009 0.0018
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0119 0.0266 0.1687
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Loa Loa (eye worm) ion channel NompC 0.0013 0.0006 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.097 0.2349 0.4591
Onchocerca volvulus Peroxidasin homolog 0.007 0.0145 0.0373
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0019 0.0044
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0036 0.0061 0.039
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0006 0.0012
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0024 0.0033 0.0075
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0184 0.0423 0.0828
Leishmania major cathepsin L-like protease 0.0073 0.0153 0.0979
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0044 0.008 0.0515
Schistosoma mansoni microtubule-associated protein tau 0.148 0.3599 0.7035
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0046 0.0297
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0013 0.0005 0.0034
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0184 0.0423 0.0961
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0006 0.0012
Plasmodium vivax vivapain-2 0.0019 0.002 0.0421
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.0276 0.0812
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0011
Schistosoma mansoni neuropeptide receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.007 0.0137
Onchocerca volvulus 0.0184 0.0423 0.1115
Schistosoma mansoni neuropeptide receptor 0.2099 0.5116 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.002 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0003
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0005 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0074 0.0154 0.0985
Giardia lamblia Aldose reductase 0.0649 0.1564 1
Loa Loa (eye worm) AIDA-1b 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0148
Brugia malayi hypothetical protein 0.0729 0.1759 0.3993
Mycobacterium tuberculosis Conserved protein 0.0156 0.0356 0.0352
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni alpha-1 adrenergic receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.001 0.0006
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0361 0.0857 0.1674
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0031 0.005 0.0098
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.002 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1545 0.3759 0.7346
Schistosoma mansoni flap endonuclease-1 0.0027 0.0039 0.0077
Entamoeba histolytica alcohol dehydrogenase, putative 0.0188 0.0434 0.2763
Plasmodium falciparum M17 leucyl aminopeptidase 0.0123 0.0274 0.562
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0006 0.0012
Loa Loa (eye worm) flavodoxin family protein 0.0012 0.0003 0.0006
Leishmania major trypanothione reductase 0.0054 0.0106 0.0679
Schistosoma mansoni NADPH flavin oxidoreductase 0.0016 0.0012 0.0023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.021 0.0476
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0184 0.0423 0.0828
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Trichomonas vaginalis set domain proteins, putative 0.0287 0.0676 0.4313
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0005 0.0018
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Leishmania major basic transcription factor 3a, putative 0.0042 0.0077 0.0491
Schistosoma mansoni neuropeptide F-like receptor 0.0184 0.0423 0.0828
Schistosoma mansoni dynamin 0.0028 0.0041 0.0081
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0044 0.008 0.0157
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0056 0.0324
Brugia malayi hypothetical protein 0.0076 0.016 0.0363
Loa Loa (eye worm) hypothetical protein 0.0042 0.0077 0.0176
Schistosoma mansoni hypothetical protein 0.0184 0.0423 0.0828
Onchocerca volvulus 0.0019 0.002 0.0042
Trypanosoma cruzi aldo-keto reductase 0.0649 0.1564 1
Echinococcus granulosus leucyl aminopeptidase 0.0024 0.0033 0.0065
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Brugia malayi CXXC zinc finger family protein 0.0033 0.0055 0.0124
Loa Loa (eye worm) hypothetical protein 0.0486 0.1164 0.2643
Entamoeba histolytica dynamin-1-like protein, putative 0.0026 0.0036 0.0216
Schistosoma mansoni hypothetical protein 0.0362 0.0859 0.1679
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0038
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0027 0.0052
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0019 0.0021 0.0133
Echinococcus multilocularis dual specificity 0.0103 0.0225 0.044
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0028 0.0055
Trypanosoma brucei trypanothione reductase 0.0054 0.0106 0.0679
Echinococcus multilocularis SHC transforming protein 3 0.0019 0.0019 0.0037
Loa Loa (eye worm) heat shock protein 75 0.0037 0.0063 0.0144
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus granulosus RUN 0.0021 0.0024 0.0047
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0101 0.074
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0033 0.0029
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0009 0.0025
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.0101 0.0643
Trichomonas vaginalis DNA helicase recq, putative 0.0028 0.0041 0.0244
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0124
Echinococcus multilocularis transfer RNA-Gly 0.0013 0.0006 0.0012
Plasmodium vivax flavodoxin domain containing protein 0.0028 0.0041 0.0847
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.021 0.041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0021
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.001 0.0023
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.007 0.0144 0.0924
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0011
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.001 0.003
Brugia malayi nuclear hormone receptor family member odr-7 0.0729 0.1759 0.3993
Echinococcus granulosus thyroid hormone receptor alpha 0.0729 0.1759 0.3438
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0063 0.0124
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0184 0.0423 0.0828
Plasmodium falciparum thioredoxin reductase 0.0054 0.0106 0.2179
Onchocerca volvulus 0.0156 0.0356 0.0935
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0383 0.2435
Echinococcus granulosus muscleblind protein 0.0486 0.1164 0.2276
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.001 0.003
Echinococcus multilocularis neuropeptide Y receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.021 0.041
Brugia malayi neuropeptide F receptor 0.0184 0.0423 0.0961
Giardia lamblia Nitric oxide synthase, inducible 0.0028 0.0041 0.0257
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0005 0.0018
Echinococcus granulosus voltage gated hydrogen channel 1 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0184 0.0423 0.1115
Echinococcus granulosus neuropeptide Y receptor 0.0184 0.0423 0.0828
Schistosoma mansoni amine GPCR 0.0184 0.0423 0.0828
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.008 0.0499
Echinococcus granulosus neuropeptides capa receptor 0.0184 0.0423 0.0828
Echinococcus granulosus aldo keto reductase 0.0649 0.1564 0.3056
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0005 0.0011
Mycobacterium ulcerans heat shock protein 90 0.0052 0.0101 0.0611
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0019 0.0124
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0001 0.0002
Plasmodium falciparum flap endonuclease 1 0.003 0.0046 0.0954
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0089 0.0571
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0005 0.0018
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0012 0.0003 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0144 0.0327
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus granulosus leucine aminopeptidase protein 0.0123 0.0274 0.0535
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0013 0.0006 0.0014
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.043 0.1026 0.2006
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0056 0.0127
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.008 0.0515
Brugia malayi Pre-SET motif family protein 0.0037 0.0063 0.0144
Brugia malayi Nuclear hormone receptor-like 1 0.0816 0.1973 0.4479
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.002 0.0114
Brugia malayi conserved hypotetical protein 0.0729 0.1759 0.3993
Loa Loa (eye worm) TK protein kinase 0.0032 0.0051 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0597 0.3809
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0006 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.021 0.041
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0079 0.0166 0.0377
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0012
Echinococcus granulosus hypothetical protein 0.0069 0.0142 0.0277
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0138 0.0879
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0096 0.0599
Toxoplasma gondii hypothetical protein 0.0013 0.0005 0.0034
Echinococcus granulosus TRP transient receptor potential channel 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.0056
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0019 0.0124
Brugia malayi Bromodomain containing protein 0.0043 0.0079 0.0179
Schistosoma mansoni hypothetical protein 0.0167 0.0383 0.0749
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1545 0.3759 0.8533
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0115 0.0226
Echinococcus granulosus methionine synthase reductase 0.0019 0.0021 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.007 0.0137
Loa Loa (eye worm) glutaminase 0.0271 0.0637 0.1446
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0024 0.0494
Echinococcus multilocularis geminin 0.0695 0.1675 0.3274
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0649 0.1564 0.4667
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0005 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0009 0.0018
Trypanosoma cruzi oligopeptidase b 0.0013 0.0005 0.0034
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0013 0.0005 0.0034
Echinococcus multilocularis transcription factor btf3 0.0042 0.0077 0.015
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0006 0.0012
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0009 0.006
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.0276 0.0272
Brugia malayi jmjC domain containing protein 0.0045 0.0083 0.0188
Toxoplasma gondii heat shock protein HSP90 0.0055 0.0109 0.0696
Loa Loa (eye worm) X11 protein 0.0139 0.0314 0.0713
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.0109 0.0696
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0061 0.0119
Onchocerca volvulus 0.0021 0.0024 0.0051
Echinococcus granulosus microtubule associated protein 2 0.148 0.3599 0.7035
Mycobacterium tuberculosis Conserved protein 0.0188 0.0434 0.043
Schistosoma mansoni potassium channel beta 0.0188 0.0434 0.0848
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.1545 0.3759 0.7346
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0309 0.0729 0.193
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0046 0.0297
Schistosoma mansoni nuclear hormone receptor 0.0729 0.1759 0.3438
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0096 0.0218
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1545 0.3759 0.7346
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.001 0.0006
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.001 0.0006
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0111 0.0244 0.0477
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0058 0.0113
Echinococcus multilocularis dual specificity protein kinase clk2 0.007 0.0144 0.0282
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0356 0.2263
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0013 0.0005 0.0018
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0009 0.0005
Echinococcus granulosus heat shock protein 0.0055 0.0109 0.0213
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0096 0.0614
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0019 0.0021 0.0133
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0109 0.068
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0061 0.0119
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0065 0.1335
Loa Loa (eye worm) hypothetical protein 0.0051 0.0099 0.0224
Echinococcus multilocularis neuropeptide receptor 0.2099 0.5116 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0019 0.0124
Plasmodium vivax dynamin-like protein, putative 0.0026 0.0036 0.0747
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0184 0.0423 0.0961
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Wolbachia endosymbiont of Brugia malayi recombinase A 0.013 0.0293 0.249
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0033 0.0277
Plasmodium vivax SET domain containing protein 0.0011 0.0001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0013 0.0006 0.0012
Schistosoma mansoni bromodomain containing protein 0.0013 0.0006 0.0011
Entamoeba histolytica hypothetical protein 0.0042 0.0077 0.0475
Brugia malayi CED-6 protein 0.0015 0.0009 0.0021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0529 0.1269 0.2881
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.1545 0.3759 0.7346
Loa Loa (eye worm) oxidoreductase 0.0015 0.0009 0.0021
Loa Loa (eye worm) nuclear hormone receptor 0.0729 0.1759 0.3993
Echinococcus granulosus bloom syndrome protein 0.0028 0.0041 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Brugia malayi Isocitrate dehydrogenase 0.0036 0.0061 0.0138
Brugia malayi Animal haem peroxidase family protein 0.007 0.0145 0.0329
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0115 0.0226
Schistosoma mansoni biogenic amine receptor 0.0184 0.0423 0.0828
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0013 0.0006 0.0014
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trichomonas vaginalis penicillin-binding protein, putative 0.0156 0.0356 0.2263
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.007 0.0137
Onchocerca volvulus 0.0019 0.002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0649 0.1564 0.355
Schistosoma mansoni DNA helicase recq5 0.0011 0.0001 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0019 0.0124
Schistosoma mansoni rab6-interacting 0.0021 0.0024 0.0047
Echinococcus granulosus g protein coupled receptor 0.0184 0.0423 0.0828
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.001 0.002
Brugia malayi neuropeptide F receptor 0.0184 0.0423 0.0961
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0356 0.2263
Loa Loa (eye worm) beta-lactamase 0.0156 0.0356 0.0808
Entamoeba histolytica protein kinase, putative 0.0103 0.0225 0.1427
Schistosoma mansoni aldo-keto reductase 0.0649 0.1564 0.3056
Onchocerca volvulus 0.0184 0.0423 0.1115
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0028 0.0041 0.0247
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.003 0.0192
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0096 0.0272
Onchocerca volvulus Peroxidasin homolog 0.007 0.0145 0.0373
Onchocerca volvulus 0.0019 0.002 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Brugia malayi RE15519p 0.0184 0.0423 0.0961
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.002 0.004
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.007 0.0137
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0006 0.0024
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0009 0.006
Schistosoma mansoni shc transforming protein 0.0019 0.0019 0.0037
Brugia malayi AKH receptor 0.0184 0.0423 0.0961
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.012 0.0235
Giardia lamblia Hypothetical protein 0.0028 0.0041 0.0257
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Loa Loa (eye worm) isocitrate dehydrogenase 0.0036 0.0061 0.0138
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0109 0.0696
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0056 0.0109 0.0214
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0061 0.0119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Echinococcus granulosus leucyl aminopeptidase 0.0024 0.0033 0.0065
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0184 0.0423 0.0961
Brugia malayi MH2 domain containing protein 0.0137 0.0309 0.0701
Onchocerca volvulus Chorion peroxidase homolog 0.007 0.0145 0.0373
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0033 0.018
Brugia malayi Doublecortin family protein 0.0021 0.0024 0.0055
Plasmodium falciparum dynamin-like protein 0.0026 0.0036 0.0747
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.001 0.003
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0006 0.0012
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.043 0.1026 0.2006
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0022
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.0109 0.0696
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Trypanosoma brucei prostaglandin f synthase 0.0649 0.1564 1
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0188 0.0434 0.891
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0019 0.0021 0.0116
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0013 0.0006 0.0014
Echinococcus granulosus sodium channel protein 0.0052 0.0102 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0055
Onchocerca volvulus 0.0184 0.0423 0.1115
Schistosoma mansoni calcium-activated potassium channel 0.0013 0.0006 0.0012
Echinococcus multilocularis heat shock protein 0.0055 0.0109 0.0213
Onchocerca volvulus 0.0033 0.0055 0.0133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0019 0.0089
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0187 0.0366
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Echinococcus multilocularis g-protein coupled receptor 0.0184 0.0423 0.0828
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0009 0.0043
Echinococcus multilocularis peregrin 0.0043 0.0079 0.0154
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.007 0.0144 0.0924
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Schistosoma mansoni tyrosine kinase 0.004 0.007 0.0137
Brugia malayi AMP-binding enzyme family protein 0.005 0.0096 0.0218
Echinococcus granulosus endoplasmin 0.0052 0.0101 0.0196
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0056 0.0109 0.07
Echinococcus granulosus Nuclear hormone receptor HR96 0.0729 0.1759 0.3438
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0184 0.0423 0.0828
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0013 0.0006 0.0014
Schistosoma mansoni hypothetical protein 0.0011 0 0.0001
Echinococcus multilocularis aldo keto reductase 0.0649 0.1564 0.3056
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0144 0.0282
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0165 0.0378 0.0739
Giardia lamblia DNA repair protein RAD52 0.042 0.1002 0.6404
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0031 0.005 0.0098
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0006 0.0012
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0024 0.0055
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0009 0.0005
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0036 0.0061 0.0119
Schistosoma mansoni neuropeptide f receptor 76f 0.0184 0.0423 0.0828
Brugia malayi AF-10 protein 0.0011 0 0.0001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0033 0.018
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0006 0.0012
Onchocerca volvulus 0.0184 0.0423 0.1115
Echinococcus granulosus dynamin 1 protein 0.0026 0.0036 0.0071
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0046 0.0281
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0187 0.0425
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0006 0.0012
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0031 0.005 0.032
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.0186 0.382
Echinococcus granulosus dynamin 0.0026 0.0036 0.0071
Mycobacterium ulcerans leucyl aminopeptidase 0.0123 0.0274 0.1722
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.001 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0096 0.1972
Entamoeba histolytica protein kinase, putative 0.0032 0.0051 0.031
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0056 0.0357
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0031 0.005 0.0098
Echinococcus multilocularis aldehyde reductase 0.0461 0.1103 0.2156
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0096 0.0614
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0188 0.0434 0.2775
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0019 0.0124
Echinococcus multilocularis bloom syndrome protein 0.0028 0.0041 0.008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0061 0.0119
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0024 0.0033 0.0065
Giardia lamblia Dynamin 0.0026 0.0036 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Giardia lamblia Thymus-specific serine protease precursor 0.0019 0.0021 0.0126
Loa Loa (eye worm) hypothetical protein 0.0079 0.0166 0.0377
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0006 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0019 0.0397
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0021 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Trichomonas vaginalis aldo-keto reductase, putative 0.0188 0.0434 0.2763
Echinococcus granulosus dual specificity protein kinase clk2 0.007 0.0144 0.0282
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Echinococcus multilocularis methionine synthase reductase 0.0019 0.0021 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Brugia malayi Nuclear hormone receptor family member nhr-1 0.1545 0.3759 0.8533
Entamoeba histolytica aldose reductase, putative 0.0649 0.1564 1
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0013 0.0006 0.0014
Brugia malayi isocitrate dehydrogenase 0.0036 0.0061 0.0138
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0156 0.0356 0.2249
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus multilocularis 0.0069 0.0142 0.0277
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Loa Loa (eye worm) DR-78 0.0729 0.1759 0.3993
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0356 0.2276
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0005
Treponema pallidum heat shock protein 90 0.0052 0.0101 0.0879
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.043 0.1026 0.2006
Onchocerca volvulus 0.0184 0.0423 0.1115
Echinococcus multilocularis neuropeptide s receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable lipase LipD 0.0156 0.0356 0.0352
Echinococcus granulosus hypothetical protein 0.0013 0.0006 0.0012
Brugia malayi cation channel family protein 0.0013 0.0006 0.0014
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0013 0.0006 0.0004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0156 0.0356 0.0352
Echinococcus granulosus hypothetical protein 0.0015 0.0009 0.0018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.0056
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.007 0.0137
Echinococcus granulosus acylamino acid releasing enzyme 0.0013 0.0005 0.0011
Onchocerca volvulus 0.0188 0.0434 0.1143
Echinococcus multilocularis serotonin receptor 0.0184 0.0423 0.0828
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0096 0.0582
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.029 0.0683 0.1335
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0649 0.1564 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0184 0.0423 0.0961
Brugia malayi Animal haem peroxidase family protein 0.007 0.0145 0.0329
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.1545 0.3759 0.7346
Echinococcus granulosus GPCR family 2 0.0167 0.0383 0.0749
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.2099 0.5116 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0033 0.0214
Trypanosoma brucei prolyl oligopeptidase, putative 0.0013 0.0005 0.0034
Echinococcus granulosus tyrosine protein kinase HCK 0.0032 0.0051 0.01
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis neuropeptide FF receptor 2 0.0184 0.0423 0.0828
Entamoeba histolytica hypothetical protein 0.0076 0.016 0.1008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0005 0.0014
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.008 0.0499
Treponema pallidum replicative DNA helicase (dnaB) 0.0467 0.1117 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0028 0.0041 0.0244
Echinococcus multilocularis two pore calcium channel protein 1 0.0013 0.0006 0.0012
Chlamydia trachomatis recombinase RecA 0.013 0.0293 0.249
Loa Loa (eye worm) DRP-1 protein 0.0026 0.0036 0.0083
Echinococcus granulosus orexin receptor type 2 0.0184 0.0423 0.0828
Mycobacterium ulcerans glutaminase 0.0271 0.0637 0.4052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-49 0.1668 0.406 0.9218
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei hypothetical protein, conserved 0.0156 0.0356 0.2276
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.002 0.004
Plasmodium falciparum dynamin-like protein 0.0026 0.0036 0.0747
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0065 0.0417
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0015 0.0029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0729 0.1759 0.3438
Brugia malayi Bloom's syndrome protein homolog 0.0028 0.0041 0.0093
Echinococcus granulosus shaker cognate 0.0013 0.0006 0.0012
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0109 0.0696
Schistosoma mansoni biogenic amine receptor 0.0184 0.0423 0.0828
Echinococcus granulosus histone acetyltransferase KAT2B 0.0279 0.0657 0.1285
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0044 0.008 0.0515
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0069 0.0142 0.0322
Plasmodium falciparum phd finger protein, putative 0.0034 0.0056 0.115
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0019 0.0124
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0036 0.0061 0.0057
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1545 0.3759 1
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.1545 0.3759 0.7346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Mycobacterium ulcerans oxidoreductase 0.0649 0.1564 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1545 0.3759 0.7346
Trichomonas vaginalis mgm1, putative 0.0026 0.0036 0.0216
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.0101 0.0096
Leishmania major protein kinase, putative 0.007 0.0144 0.0924
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0105 0.0205
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.043 0.1026 0.2006
Brugia malayi Peroxidasin 0.007 0.0145 0.0329
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0105 0.0205
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0056 0.0109 0.07
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0019 0.0021 0.0041
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.0109 0.0696
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0096 0.0614
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0009 0.0021
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.008 0.1652
Entamoeba histolytica hypothetical protein 0.0025 0.0033 0.0198
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0816 0.1973 0.4479
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0089 0.0555
Schistosoma mansoni voltage-dependent calcium channel 0.0013 0.0006 0.0012
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Brugia malayi AMP-binding enzyme family protein 0.005 0.0096 0.0218
Onchocerca volvulus 0.0015 0.0009 0.0012
Loa Loa (eye worm) animal heme peroxidase 0.007 0.0145 0.0329
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0023 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.0109 0.0696
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.0101 0.0285
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0184 0.0423 0.0828
Schistosoma mansoni cytochrome P450 reductase 0.0031 0.005 0.0098
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0106 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0153 0.0979
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.0077 0.1575
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0184 0.0423 0.0828
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Echinococcus granulosus G protein coupled receptor 139 0.0184 0.0423 0.0828
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Loa Loa (eye worm) acetyltransferase 0.029 0.0683 0.1551
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Loa Loa (eye worm) hypothetical protein 0.0102 0.0223 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0144 0.0282
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.0077 0.1575
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0046 0.0297
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0009 0.0043
Echinococcus granulosus peptide allatostatin:somatostatin 0.0184 0.0423 0.0828
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni 60S ribosomal protein L21 0.0013 0.0006 0.0012
Onchocerca volvulus 0.007 0.0145 0.0373
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0154 0.03
Echinococcus multilocularis serotonin receptor 0.0184 0.0423 0.0828
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0011 0 0.0002
Loa Loa (eye worm) oxidoreductase 0.0649 0.1564 0.355
Loa Loa (eye worm) steroid hormone receptor 0.1545 0.3759 0.8533
Brugia malayi protein-tyrosine kinase 0.0036 0.0061 0.0138
Entamoeba histolytica dynamin-like protein 0.0026 0.0036 0.0216
Brugia malayi Hsp90 protein 0.0037 0.0063 0.0144
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0009 0.0025
Leishmania major protein kinase, putative 0.007 0.0144 0.0924
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0096 0.0599
Schistosoma mansoni neuropeptide F-like receptor 0.0184 0.0423 0.0828
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0106 0.0207
Toxoplasma gondii thioredoxin reductase 0.0054 0.0106 0.0679
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Onchocerca volvulus 0.0184 0.0423 0.1115
Brugia malayi Bromodomain containing protein 0.0045 0.0083 0.019
Echinococcus granulosus neuropeptides capa receptor 0.0184 0.0423 0.0828
Brugia malayi Nuclear hormone receptor E75 0.0729 0.1759 0.3993
Toxoplasma gondii hypothetical protein 0.0013 0.0006 0.004
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.002 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0309 0.0729 0.1656
Entamoeba histolytica hypothetical protein 0.0103 0.0225 0.1427
Echinococcus multilocularis neuropeptide Y receptor 0.0184 0.0423 0.0828
Toxoplasma gondii dynamin-related protein DRPA 0.0026 0.0036 0.0233
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.0056
Mycobacterium ulcerans lipase LipD 0.0156 0.0356 0.2249
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0031 0.005 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0047
Echinococcus multilocularis aldo keto reductase 0.0649 0.1564 0.3056
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.002 0.004
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0012 0.0003 0.0054
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0019 0.0107
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0188 0.0434 0.0985
Toxoplasma gondii dynamin-related protein DRPB 0.0026 0.0036 0.0233
Schistosoma mansoni numb 0.0015 0.0009 0.0018
Entamoeba histolytica hypothetical protein 0.0076 0.016 0.1008
Brugia malayi Animal haem peroxidase family protein 0.007 0.0145 0.0329
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0013 0.0006 0.0012
Plasmodium vivax heat shock protein, putative 0.021 0.0487 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0012
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0036 0.0061 0.039
Brugia malayi AIDA-1b 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0019 0.0021 0.0116
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Brugia malayi ecdysone receptor 0.0729 0.1759 0.3993
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0047
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0131
Echinococcus multilocularis leucyl aminopeptidase 0.0024 0.0033 0.0065
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.0063 0.0405
Brugia malayi Dopamine receptor 0.0184 0.0423 0.0961
Echinococcus multilocularis tachykinin peptides receptor 99D 0.048 0.1149 0.2246
Onchocerca volvulus Alhambra homolog 0.0034 0.0056 0.0136
Chlamydia trachomatis replicative DNA helicase 0.0467 0.1117 1
Loa Loa (eye worm) oxidoreductase 0.0649 0.1564 0.355
Trypanosoma brucei oligopeptidase b 0.0013 0.0005 0.0034
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.014 0.0274
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0012
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0649 0.1564 0.355
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0006 0.0012
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.007 0.0137
Brugia malayi nuclear hormone receptor 0.0729 0.1759 0.3993
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0103 0.0225 0.1441
Plasmodium vivax vivapain-2 0.0019 0.002 0.0421
Onchocerca volvulus 0.0015 0.0009 0.0012
Onchocerca volvulus 0.0649 0.1564 0.4153
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0649 0.1564 0.3056
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0225 0.044
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0061 0.0119
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0006 0.0012
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.042 0.1002 0.6401
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0005 0.0109
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0729 0.1759 0.3993
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0223 0.0519 0.1015
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0005 0.0034
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.0186 0.119
Echinococcus granulosus flap endonuclease 1 0.003 0.0046 0.0091
Echinococcus granulosus biogenic amine 5HT receptor 0.0184 0.0423 0.0828
Schistosoma mansoni neuropeptide receptor 0.0184 0.0423 0.0828
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0154 0.03
Schistosoma mansoni nuclear hormone receptor 0.1545 0.3759 0.7346
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0056 0.0357
Schistosoma mansoni two-pore calcium channel 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0167 0.0383 0.0749
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0154 0.03
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0021 0.0116
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0649 0.1564 0.3056
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.013 0.0293 0.086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Toxoplasma gondii transporter, cation channel family protein 0.0092 0.0199 0.1272
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0096 0.1972
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0165 0.0378 0.0739
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.0186 0.119
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0014 0.0007 0.0016
Onchocerca volvulus 0.0037 0.0063 0.0156
Loa Loa (eye worm) hypothetical protein 0.005 0.0096 0.0218
Echinococcus multilocularis leucine aminopeptidase protein 0.0123 0.0274 0.0535
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable lipase LipE 0.0156 0.0356 0.0352
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.001 0.0064
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.001 0.0064
Mycobacterium ulcerans hypothetical protein 0.0156 0.0356 0.2249
Echinococcus granulosus transient receptor potential gamma protein 0.0013 0.0006 0.0012
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0013 0.0005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0031 0.005 0.032
Brugia malayi Nuclear hormone receptor family member nhr-14 0.1545 0.3759 0.8533
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.021 0.041
Brugia malayi PHD-finger family protein 0.0034 0.0056 0.0127
Loa Loa (eye worm) hypothetical protein 0.0087 0.0187 0.0425
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0065 0.1335
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.002 0.0114
Schistosoma mansoni tensin-related 0.0019 0.0019 0.0037
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0013 0.0006 0.0014
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Brugia malayi Serotonin receptor 0.0184 0.0423 0.0961
Loa Loa (eye worm) heat shock protein 90 0.0055 0.0109 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Brugia malayi hypothetical protein 0.005 0.0096 0.0218
Brugia malayi Endoplasmin precursor 0.0055 0.0109 0.0247
Schistosoma mansoni voltage-gated ion channel 0.0013 0.0006 0.0012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0186 0.0364
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0184 0.0423 0.0828
Echinococcus granulosus neuropeptide receptor 0.2099 0.5116 1
Echinococcus multilocularis sodium channel protein 0.0223 0.0519 0.1015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Onchocerca volvulus 0.0184 0.0423 0.1115
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0005 0.0011
Brugia malayi nuclear receptor RXR 0.0816 0.1973 0.4479
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0329
Loa Loa (eye worm) cysteine protease 0.0019 0.002 0.0047
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Trypanosoma brucei ISWI complex protein 0.0015 0.001 0.0067
Echinococcus multilocularis fmrfamide receptor 0.0184 0.0423 0.0828
Trypanosoma brucei dynamin-1-like protein 0.0026 0.0036 0.0233
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0012
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0031 0.005 0.032
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0013 0.0005 0.0011
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.007 0.0144 0.0924
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1447 0.3519 0.6878
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0056 0.0109 0.0214
Echinococcus multilocularis microtubule associated protein 2 0.148 0.3599 0.7035
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.043 0.1026 0.233
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0021 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) voltage-gated potassium channel 0.0013 0.0006 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.0056
Schistosoma mansoni nuclear receptor 0.0729 0.1759 0.3438
Onchocerca volvulus 0.0184 0.0423 0.1115
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0063 0.0405
Brugia malayi RNA binding protein 0.0074 0.0154 0.0349
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0065 0.0383
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0044 0.008 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0184 0.0423 0.0828
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0001 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.007 0.0145 0.0329
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0816 0.1973 0.3856
Loa Loa (eye worm) SRC-1 0.004 0.007 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.002 0.0114
Brugia malayi FAD binding domain containing protein 0.0031 0.005 0.0113
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0019 0.0124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Mycobacterium tuberculosis Probable hydrolase 0.0156 0.0356 0.0352
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.002 0.004
Echinococcus granulosus transcription factor btf3 0.0042 0.0077 0.015
Plasmodium falciparum heat shock protein 90 0.0055 0.0109 0.2235
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.001 0.003
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0009 0.006
Schistosoma mansoni cpg binding protein 0.0037 0.0064 0.0125
Schistosoma mansoni hypothetical protein 0.0184 0.0423 0.0828
Brugia malayi Nuclear hormone receptor-like 1 0.0816 0.1973 0.4479
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0361 0.0857 0.1674
Schistosoma mansoni hypothetical protein 0.0184 0.0423 0.0828
Echinococcus granulosus dual specificity 0.0103 0.0225 0.044
Loa Loa (eye worm) hypothetical protein 0.0649 0.1564 0.355
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Echinococcus multilocularis 0.0015 0.001 0.002
Giardia lamblia Aldose reductase 0.0649 0.1564 1
Brugia malayi Cytochrome P450 family protein 0.0034 0.0056 0.0127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0056 0.0127
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0998 0.2418 0.2414
Trypanosoma cruzi ISWI complex protein 0.0015 0.001 0.0067
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0184 0.0423 0.0961
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0009 0.0018
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.001 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0105 0.0205
Onchocerca volvulus 0.007 0.0145 0.0373
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.008 0.1652
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Onchocerca volvulus 0.005 0.0096 0.0243
Echinococcus multilocularis peroxidasin 0.007 0.0145 0.0283
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.001 0.0064
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0019 0.0021 0.0116
Loa Loa (eye worm) hypothetical protein 0.0816 0.1973 0.4479
Echinococcus granulosus hypothetical protein 0.0184 0.0423 0.0828
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0019 0.0124
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.0063 0.0124
Brugia malayi Mammalian fe65 homolog protein 1 0.0015 0.0009 0.0021
Echinococcus multilocularis dynamin 0.0026 0.0036 0.0071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0024 0.0047
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0024 0.0033 0.0065
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0006 0.0012
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0184 0.0423 0.0828
Brugia malayi hypothetical protein 0.0816 0.1973 0.4479
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0184 0.0423 0.0828
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0056 0.0109 0.07
Echinococcus multilocularis acylamino acid releasing enzyme 0.0013 0.0005 0.0011
Brugia malayi Serine protease Z688.6 precursor 0.0019 0.0021 0.0047
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.007 0.0144 0.0924
Schistosoma mansoni endoplasmin 0.0055 0.0109 0.0213
Loa Loa (eye worm) prolyl oligopeptidase 0.0013 0.0005 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0024 0.0047
Schistosoma mansoni hypothetical protein 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.1809 0.4405 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.007 0.0137
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0009 0.0018
Echinococcus multilocularis endoplasmin 0.0052 0.0101 0.0196
Trypanosoma cruzi ISWI complex protein 0.0015 0.001 0.0067
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0148
Plasmodium falciparum histone acetyltransferase GCN5 0.0077 0.0163 0.3348
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0729 0.1759 0.3993
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0063 0.0124
Schistosoma mansoni hypothetical protein 0.0695 0.1675 0.3274
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Brugia malayi Dynamin 0.0028 0.0041 0.0094
Mycobacterium tuberculosis Conserved protein 0.0156 0.0356 0.0352
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.001 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0729 0.1759 0.3438
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1447 0.3519 0.6878
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.0063 0.0405
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Echinococcus multilocularis shaker cognate 0.0013 0.0006 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0001 0.0007
Trypanosoma brucei aldo/keto reductase, putative 0.0188 0.0434 0.2775
Onchocerca volvulus 0.0015 0.0009 0.0012
Onchocerca volvulus 0.0021 0.0024 0.0051
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0033 0.0064
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.1545 0.3759 0.7346
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0058 0.0113
Brugia malayi steroid hormone receptor 0.1545 0.3759 0.8533
Plasmodium vivax hypothetical protein, conserved 0.0156 0.0356 0.7306
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.014 0.0274
Schistosoma mansoni diflavin oxidoreductase 0.0016 0.0011 0.0022
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0088 0.0173
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0154 0.03
Echinococcus multilocularis short transient receptor potential channel 6 0.0013 0.0006 0.0012
Plasmodium vivax endoplasmin, putative 0.0055 0.0109 0.2235
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.016 0.0313
Echinococcus granulosus FTZ F1 alpha 0.1545 0.3759 0.7346
Echinococcus multilocularis dnaJ subfamily B 0.0474 0.1134 0.2217
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Leishmania major oligopeptidase b 0.0013 0.0005 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0649 0.1564 1
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0056 0.0109 0.07
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.001 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0184 0.0423 0.0828
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Entamoeba histolytica aldose reductase, putative 0.0649 0.1564 1
Schistosoma mansoni zinc finger protein 0.0015 0.001 0.002
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0729 0.1759 0.3993
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.004 0.0072 0.0458
Brugia malayi Nuclear hormone receptor E75 0.0729 0.1759 0.3993
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0031 0.005 0.0286
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0009 0.0043
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.012 0.0767
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.1545 0.3759 0.8533
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0024 0.0494
Brugia malayi sulfakinin receptor protein 0.0184 0.0423 0.0961
Onchocerca volvulus 0.0649 0.1564 0.4153
Loa Loa (eye worm) voltage-dependent calcium channel 0.0092 0.0199 0.0452
Echinococcus granulosus g protein coupled receptor 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei prolyl endopeptidase 0.0013 0.0005 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0114
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0033 0.0687
Echinococcus multilocularis biogenic amine (5HT) receptor 0.097 0.2349 0.4591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Brugia malayi Serine carboxypeptidase S28 family protein 0.0019 0.0021 0.0047
Giardia lamblia Grp94/Hsp90 0.0052 0.0101 0.0636
Plasmodium falciparum glutathione reductase 0.0054 0.0106 0.2179
Trichomonas vaginalis aldo-keto reductase, putative 0.0188 0.0434 0.2763
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0184 0.0423 0.0828
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.031 0.0913
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.0001 0.0023
Loa Loa (eye worm) twinkle helicase 0.0133 0.03 0.0681
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0005 0.001
Trichomonas vaginalis dynamin, putative 0.0026 0.0036 0.0216
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0188 0.0434 0.0848
Brugia malayi hypothetical protein 0.0184 0.0423 0.0961
Onchocerca volvulus 0.0019 0.002 0.0042
Brugia malayi Cytochrome P450 family protein 0.0034 0.0056 0.0127
Schistosoma mansoni thyroid hormone receptor 0.1545 0.3759 0.7346
Onchocerca volvulus 0.0287 0.0676 0.1788
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0061 0.0118
Echinococcus granulosus short transient receptor potential channel 6 0.0013 0.0006 0.0012
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0013 0.0006 0.0012
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.0063 0.0156
Echinococcus multilocularis orexin receptor type 2 0.0184 0.0423 0.0828
Onchocerca volvulus Peroxidase homolog 0.007 0.0145 0.0373
Schistosoma mansoni pol-related 0.0649 0.1564 0.3056
Loa Loa (eye worm) CMGC/CLK protein kinase 0.007 0.0144 0.0328
Schistosoma mansoni transient receptor potential channel 4 0.0013 0.0006 0.0012
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0006 0.0012
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0184 0.0423 0.0961
Onchocerca volvulus Neuropeptide F receptor homolog 0.0184 0.0423 0.1115
Brugia malayi Bromodomain containing protein 0.0083 0.0177 0.0402
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0031 0.005 0.032
Brugia malayi TBC domain containing protein 0.0015 0.0009 0.0021
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0262 0.0616 0.3942
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0148
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0077 0.0491
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0015 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0058 0.0115 0.0261
Echinococcus multilocularis muscleblind protein 0.0486 0.1164 0.2276
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0013 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.0434 0.2763
Echinococcus multilocularis g protein coupled receptor 0.0184 0.0423 0.0828
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.0184 0.0423 0.0961
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0013 0.0006 0.0014
Brugia malayi Pre-SET motif family protein 0.0252 0.0591 0.1341
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.001 0.0006
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0101 0.0627
Schistosoma mansoni biogenic amine (5HT) receptor 0.097 0.2349 0.4591
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0012
Entamoeba histolytica hypothetical protein 0.0119 0.0266 0.1687
Echinococcus granulosus amyloid beta A4 protein 0.0139 0.0314 0.0614
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0096 0.0092
Onchocerca volvulus 0.0015 0.0009 0.0012
Leishmania major heat shock protein 83-1 0.0055 0.0109 0.0696
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0009 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-3 0.1545 0.3759 0.8533
Leishmania major cytochrome p450-like protein 0.0015 0.001 0.0064
Schistosoma mansoni zinc finger protein 0.0028 0.0043 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.012 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0018
Mycobacterium tuberculosis Probable peptidase 0.0013 0.0005 0.0001
Schistosoma mansoni hypothetical protein 0.0167 0.0383 0.0749
Onchocerca volvulus 0.0649 0.1564 0.4153
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.012 0.0735
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0056 0.0109 0.07
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0006 0.0012
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.1545 0.3759 0.7346
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0077 0.0475
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0025
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0184 0.0423 0.1115
Loa Loa (eye worm) glutathione reductase 0.0054 0.0106 0.0241
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.001 0.0006
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0188 0.0434 0.2775
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0031 0.005 0.032
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.001 0.0006
Plasmodium vivax glutathione reductase, putative 0.0054 0.0106 0.2179
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Brugia malayi ecdysteroid receptor 0.1545 0.3759 0.8533
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Trypanosoma brucei heat shock protein, putative 0.0055 0.0109 0.0696
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0165 0.0378 0.0995
Loa Loa (eye worm) ryanodine receptor 0.0013 0.0006 0.0014
Echinococcus granulosus sex peptide receptor 0.0184 0.0423 0.0828
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0006 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0052 0.0317
Brugia malayi Animal haem peroxidase family protein 0.007 0.0145 0.0329
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.007 0.0137
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0014
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0123 0.0274 0.2318
Schistosoma mansoni amine GPCR 0.0184 0.0423 0.0828
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.0276 0.0272
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.012 0.0767
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0014
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0009 0.0005
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.007 0.0137
Brugia malayi Dopamine receptor protein 2 0.0184 0.0423 0.0961
Onchocerca volvulus 0.0015 0.0009 0.0012
Schistosoma mansoni heat shock protein 0.0055 0.0109 0.0213
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0065 0.0061
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0015 0.0029
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0033 0.0214
Leishmania major cytochrome p450-like protein 0.0015 0.001 0.0064
Brugia malayi ORL1-like opioid receptor 0.0184 0.0423 0.0961
Echinococcus multilocularis ecdysone induced protein 78C 0.1545 0.3759 0.7346
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0109 0.068
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0013 0.0006 0.0014
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0044 0.008 0.0183
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0056 0.0358
Plasmodium vivax heat shock protein 86, putative 0.0055 0.0109 0.2235
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0021 0.0116
Toxoplasma gondii hypothetical protein 0.0079 0.0166 0.1061
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0019 0.0021 0.004
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0184 0.0423 0.0961
Leishmania major p450 reductase, putative 0.0031 0.005 0.032
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0006 0.004
Echinococcus multilocularis sodium leak channel non selective protein 0.0013 0.0006 0.0012
Leishmania major hypothetical protein, conserved 0.0156 0.0356 0.2276
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0046 0.0954
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0096 0.0614
Trichomonas vaginalis heat shock protein, putative 0.0055 0.0109 0.068
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0019 0.0124
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0088 0.0173
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0061 0.039
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0131
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0003 0.0054
Schistosoma mansoni nuclear receptor nhr-48 0.0729 0.1759 0.3438
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Brugia malayi nuclear hormone receptor family member nhr-6 0.0729 0.1759 0.3993
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.031 0.0306
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0006 0.0012
Loa Loa (eye worm) RecQ helicase 0.0028 0.0041 0.0093
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0024 0.0033 0.0212
Brugia malayi beta-lactamase 0.0156 0.0356 0.0808
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0047
Loa Loa (eye worm) hypothetical protein 0.1545 0.3759 0.8533
Brugia malayi G protein-coupled receptor F59B2.13 0.0184 0.0423 0.0961
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0033 0.0214
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.1545 0.3759 0.7346
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0006 0.0012
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.001 0.003
Trypanosoma cruzi heat shock protein, putative 0.0037 0.0063 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0114
Giardia lamblia PHD finger protein 15 0.0034 0.0056 0.0351
Echinococcus granulosus protein numb 0.0015 0.0009 0.0018
Entamoeba histolytica alcohol dehydrogenase, putative 0.0188 0.0434 0.2763
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0356 0.2276
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0153 0.0979
Brugia malayi photoreceptor-specific nuclear receptor 0.1545 0.3759 0.8533
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0012
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.001 0.003
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0184 0.0423 0.0828
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0089 0.0564
Brugia malayi G-protein coupled receptor 0.0184 0.0423 0.0961
Trichomonas vaginalis heat shock protein, putative 0.004 0.0072 0.0442
Echinococcus granulosus rhodopsin orphan GPCR 0.0184 0.0423 0.0828
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961
Toxoplasma gondii flavodoxin domain-containing protein 0.0016 0.0011 0.0073
Schistosoma mansoni amine GPCR 0.0184 0.0423 0.0828
Echinococcus granulosus tm gpcr rhodopsin 0.0184 0.0423 0.0828
Schistosoma mansoni lipoxygenase 0.0058 0.0115 0.0226
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0852 0.206 0.4027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0061 0.0119
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0649 0.1564 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0005 0.0111
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0033 0.0064
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0018 0.0117
Loa Loa (eye worm) hypothetical protein 0.005 0.0096 0.0218
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.016 0.0313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0061 0.0118
Echinococcus multilocularis zinc finger protein 0.0028 0.0043 0.0083
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0006 0.0012
Mycobacterium ulcerans esterase/lipase LipP 0.0156 0.0356 0.2249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1545 0.3759 0.8533
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0009 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0077 0.0475
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0019 0.0397
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0013 0.0005 0.0001
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0131
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.008 0.0183
Echinococcus granulosus zinc finger protein 0.0028 0.0043 0.0083
Brugia malayi Blistered cuticle protein 3 0.007 0.0145 0.0329
Echinococcus multilocularis neuropeptides capa receptor 0.0184 0.0423 0.0828
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0144 0.0909
Brugia malayi putative neuropeptide receptor NPR1 0.0184 0.0423 0.0961
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0103 0.0225 0.1441
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.002 0.004
Echinococcus multilocularis neuropeptide receptor 0.0184 0.0423 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0153 0.0979
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0154 0.03
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0055 0.0124
Loa Loa (eye worm) RNA binding protein 0.0074 0.0154 0.0349
Echinococcus granulosus cpg binding protein 0.0037 0.0064 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0184 0.0423 0.0828
Entamoeba histolytica hypothetical protein 0.0076 0.016 0.1008
Loa Loa (eye worm) hypothetical protein 0.0156 0.0356 0.0808
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0683
Loa Loa (eye worm) hypothetical protein 0.0184 0.0423 0.0961

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) = 1.155 uM PUBCHEM_BIOASSAY: HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
AC50 (functional) = 4.042 uM PUBCHEM_BIOASSAY: Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
AC50 (functional) = 4.561 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] ChEMBL. No reference
AC50 (functional) = 8.98 uM PubChem BioAssay. FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
AC50 (functional) = 10.92 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] ChEMBL. No reference
EC50 (functional) = 2.194 um PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) > 3.322 um PUBCHEM_BIOASSAY: Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R). (Class of assay: confirmatory) [Related pubchem assays: 2435 (Primary screen (OXTR agonists in singlicate)), 434991 (Counterscreen (V1R agonists in triplicate)), 2482 (Summary (OXTR agonists)), 434963 (Confirmation screen (OXTR agonists in triplicate)), 2797 (Counterscreen (V1R agonists in singlicate))] ChEMBL. No reference
EC50 (functional) = 13.2 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2097, AID2223, AID489010, AID492950] ChEMBL. No reference
EC50 (functional) = 23.248 um PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1902 (Retest at Dose), 1900 (Counter Screen), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) > 29.904 um PUBCHEM_BIOASSAY: Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR). (Class of assay: confirmatory) [Related pubchem assays: 2435 (Primary screen (OXTR agonists in singlicate)), 434991 (Counterscreen (V1R agonists in triplicate)), 2482 (Summary (OXTR agonists)), 434963 (Confirmation screen (OXTR agonists in triplicate))] ChEMBL. No reference
Potency (functional) 2.6169 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 3.2944 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 6.74 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.8832 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.2815 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.9145 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8325 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8325 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.847 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 30.7314 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 37.5751 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 49.128 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 49.128 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 55.1225 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 55.1225 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 55.1225 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 55.1225 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 61.8485 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 112.2018 uM PubChem BioAssay. qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Saccharomyces cerevisiae ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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