Detailed information for compound 1670783

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.953 | Formula: C24H30ClNO3
  • H donors: 0 H acceptors: 1 LogP: 5.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cc1OC)C[C@@H](C2=O)CC1CCN(CC1)Cc1ccccc1.Cl
  • InChi: 1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H/t20-;/m0./s1
  • InChiKey: XWAIAVWHZJNZQQ-BDQAORGHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Torpedo californica Acetylcholinesterase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Acetylcholinesterase   586 aa 602 aa 24.4 %
Schistosoma japonicum ko:K01050 cholinesterase [EC3.1.1.8], putative Acetylcholinesterase   586 aa 577 aa 33.6 %
Drosophila melanogaster CG10175 gene product from transcript CG10175-RE Acetylcholinesterase   586 aa 535 aa 31.4 %
Onchocerca volvulus Molybdopterin synthase catalytic subunit homolog Acetylcholinesterase   586 aa 588 aa 28.1 %
Onchocerca volvulus Putative nuclear protein Acetylcholinesterase   586 aa 551 aa 40.7 %
Echinococcus multilocularis neuroligin Acetylcholinesterase   586 aa 487 aa 23.0 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   586 aa 509 aa 24.8 %
Onchocerca volvulus Acetylcholinesterase   586 aa 562 aa 25.1 %
Schistosoma mansoni gliotactin Acetylcholinesterase   586 aa 474 aa 31.6 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 592 aa 28.0 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 546 aa 29.3 %
Onchocerca volvulus Carnitine O-palmitoyltransferase 2, mitochondrial homolog Acetylcholinesterase   586 aa 552 aa 37.7 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   586 aa 480 aa 24.6 %
Onchocerca volvulus Acetylcholinesterase   586 aa 564 aa 29.4 %
Echinococcus granulosus neuroligin Acetylcholinesterase   586 aa 493 aa 21.5 %
Echinococcus granulosus BC026374 protein S09 family Acetylcholinesterase   586 aa 648 aa 32.6 %
Onchocerca volvulus Acetylcholinesterase   586 aa 612 aa 25.5 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   586 aa 571 aa 25.0 %
Echinococcus multilocularis BC026374 protein (S09 family) Acetylcholinesterase   586 aa 643 aa 32.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0021 0.002
Loa Loa (eye worm) mbt repeat family protein 0.0105 0.0253 0.0253
Trichomonas vaginalis tubulin gamma chain, putative 0.0258 0.0674 1
Echinococcus multilocularis g protein coupled receptor 0.002 0.0021 0.0045
Echinococcus multilocularis acetylcholinesterase 0.0778 0.2098 0.4569
Echinococcus granulosus Tubulin alpha 1 chain 0.0207 0.0532 0.2535
Brugia malayi sulfakinin receptor protein 0.002 0.0021 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0056 0.0055
Echinococcus granulosus pyruvate kinase 0.0036 0.0066 0.0309
Brugia malayi mbt repeat family protein 0.0105 0.0253 0.1202
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.0293 0.0292
Schistosoma mansoni gliotactin 0.0131 0.0326 0.0325
Trichomonas vaginalis tubulin beta chain, putative 0.0082 0.019 0.2821
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0007 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni pyruvate kinase 0.0019 0.0017 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0072 0.0903
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.002 0.0093
Schistosoma mansoni amine GPCR 0.002 0.0021 0.002
Echinococcus multilocularis voltage gated potassium channel subunit 0.0015 0.0007 0.0013
Brugia malayi Dopamine receptor protein 1 0.002 0.0021 0.0097
Loa Loa (eye worm) tubulin alpha chain 0.0207 0.0532 0.0532
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.011 0.1366
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0015 0.0007 0.0085
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.366 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0071 0.0153
Brugia malayi RNA binding protein 0.0068 0.0153 0.0728
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0014 0.0161
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0085 0.04
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.006 0.0129
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0021 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Echinococcus multilocularis tubulin subunit TubB 0.0207 0.0532 0.1159
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0131 0.0326 0.0708
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.019 0.2821
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0276 0.4098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Echinococcus granulosus intermediate filament protein 0.003 0.0049 0.0227
Toxoplasma gondii aldose reductase, putative 0.0052 0.0108 0.1342
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0305 0.0802 1
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0074 0.016
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Brugia malayi hypothetical protein 0.0014 0.0005 0.0021
Echinococcus multilocularis Tubulin beta 2C chain 0.0258 0.0674 0.1467
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0067 0.0987
Schistosoma mansoni biogenic amine receptor 0.002 0.0021 0.002
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0305 0.0802 0.0802
Brugia malayi Carboxylesterase family protein 0.0131 0.0326 0.155
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0021 0.0097
Trichomonas vaginalis ornithine decarboxylase, putative 0.0202 0.052 0.7719
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.011 0.1357
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0988
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0067 0.0066
Brugia malayi G-protein coupled receptor 0.002 0.0021 0.0097
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0041 0.019
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0005 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0276 0.3436
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0023 0.0108
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0021 0.0255
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0071 0.0335
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.001 0.0044
Brugia malayi ecdysteroid receptor 0.0031 0.005 0.0232
Trypanosoma brucei beta tubulin 0.0258 0.0674 0.84
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Trypanosoma brucei ornithine decarboxylase 0.0202 0.052 0.6485
Trypanosoma cruzi aldo/keto reductase, putative 0.0052 0.0108 0.1333
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0057 0.0123
Echinococcus granulosus tubulin alpha 3 chain 0.0207 0.0532 0.2535
Echinococcus granulosus para nitrobenzyl esterase 0.0131 0.0326 0.155
Onchocerca volvulus Huntingtin homolog 0.0143 0.0358 0.446
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.003 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0349 0.0348
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.0106 0.0503
Echinococcus multilocularis neuropeptide receptor 0.002 0.0021 0.0045
Loa Loa (eye worm) follicle stimulating hormone receptor 0.002 0.0021 0.0021
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0021 0.0022 0.0269
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0023 0.003 0.0139
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0005 0.0055
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.005 0.005
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.002 0.0243
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.005 0.0232
Schistosoma mansoni hypothetical protein 0.0043 0.0085 0.0084
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0013 0.0001 0.0012
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0022 0.0047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072
Brugia malayi Cytochrome P450 family protein 0.0027 0.0039 0.018
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0067 0.0143
Loa Loa (eye worm) ABC transporter 0.0018 0.0014 0.0014
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0073 0.0166 0.0165
Schistosoma mansoni rab6-interacting 0.0021 0.0023 0.0023
Trichomonas vaginalis aldo-keto reductase, putative 0.0015 0.0007 0.0101
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0021 0.0045
Trichomonas vaginalis tubulin, putative 0.0082 0.019 0.2821
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0015 0.0007 0.0029
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0021 0.0097
Brugia malayi G protein-coupled receptor 0.002 0.0021 0.0097
Schistosoma mansoni tubulin subunit epsilon 0.0145 0.0362 0.0362
Leishmania major cathepsin L-like protease 0.0083 0.0192 0.2391
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0041 0.0508
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0066 0.081
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0013 0.0001 0.0012
Schistosoma mansoni zinc finger protein 0.0014 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Brugia malayi follicle stimulating hormone receptor 0.002 0.0021 0.0097
Echinococcus multilocularis tubulin alpha chain 0.0207 0.0532 0.1159
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0033
Onchocerca volvulus 0.0257 0.067 0.8349
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Echinococcus granulosus histone lysine methyltransferase setb 0.007 0.0159 0.0753
Schistosoma mansoni cpg binding protein 0.0037 0.0067 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0011
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Trypanosoma brucei beta tubulin 0.0145 0.0362 0.4517
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0018 0.0015 0.003
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Giardia lamblia ABC transporter 0.002 0.0021 0.0256
Brugia malayi Tubulin alpha chain 0.0207 0.0532 0.2535
Mycobacterium ulcerans diaminopimelate decarboxylase LysA 0.0202 0.052 0.0519
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0034 0.0058 0.0057
Brugia malayi Cathepsin L-like cysteine proteinase 0.0025 0.0033 0.0154
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0005 0.001
Echinococcus multilocularis carboxylesterase 5A 0.0778 0.2098 0.4569
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0005 0.001
Echinococcus multilocularis neuroligin 0.0131 0.0326 0.0708
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.005 0.0232
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.008 0.1187
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0256 0.1215
Brugia malayi hypothetical protein 0.0131 0.0326 0.155
Echinococcus granulosus pyruvate kinase 0.0019 0.0017 0.0077
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0305 0.0802 1
Loa Loa (eye worm) tubulin alpha 2 0.0144 0.036 0.036
Schistosoma mansoni hypothetical protein 0.0644 0.1732 0.1732
Onchocerca volvulus Huntingtin homolog 0.0143 0.0358 0.446
Toxoplasma gondii diaminopimelate decarboxylase 0.0202 0.052 0.6485
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0021 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0778 0.2098 0.2098
Brugia malayi RE18450p 0.0305 0.0802 0.3821
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0021 0.002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0072 0.0078
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0037 0.0067 0.082
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0021 0.0097
Trichomonas vaginalis steroid dehydrogenase, putative 0.0013 0.0001 0.0012
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0005 0.0021
Echinococcus multilocularis zinc finger protein 0.0045 0.0088 0.0191
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.003 0.014
Echinococcus granulosus g protein coupled receptor 0.002 0.0021 0.0097
Echinococcus multilocularis orexin receptor type 2 0.002 0.0021 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0067 0.082
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0017 0.0212
Toxoplasma gondii oxidoreductase, putative 0.0013 0.0001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.005 0.005
Echinococcus multilocularis somatostatin receptor 0.002 0.0021 0.0045
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0032 0.0148
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Onchocerca volvulus 0.0052 0.0108 0.1333
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0072 0.0893
Echinococcus multilocularis tubulin alpha chain 0.0207 0.0532 0.1159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0071 0.1056
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0066 0.0065
Echinococcus granulosus geminin 0.0183 0.0468 0.2228
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0005 0.0021
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0021 0.0021
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0039 0.0039
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0021 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.005 0.0232
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.0053 0.0053
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.005 0.0049
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0349 0.0759
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.005 0.0232
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0039 0.0039
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0113 0.0276 0.3436
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis tubulin alpha 3 chain 0.0207 0.0532 0.1159
Trypanosoma cruzi ISWI complex protein 0.0034 0.0058 0.0711
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.005 0.0232
Brugia malayi hypothetical protein 0.0034 0.0059 0.0275
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0023 0.0283
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0017 0.0259
Entamoeba histolytica tubulin alpha-1 chain 0.0207 0.0532 0.6635
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.002 0.0253
Echinococcus multilocularis cysteine protease 0.0037 0.0067 0.0143
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0126 0.0126
Brugia malayi beta-lactamase family protein 0.0039 0.0072 0.0341
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0021 0.0097
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0021 0.0045
Brugia malayi steroid hormone receptor 0.0031 0.005 0.0232
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0022 0.0047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0021 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0021 0.0097
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.0155 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Onchocerca volvulus 0.0131 0.0326 0.4057
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0022 0.0022
Trypanosoma cruzi ISWI complex protein 0.0034 0.0058 0.0711
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0023 0.0049
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0063 0.0138 0.2046
Trichomonas vaginalis tubulin, putative 0.0082 0.019 0.2821
Plasmodium vivax ABC transporter G family member 2, putative 0.0021 0.0022 0.0269
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.011 0.1364
Echinococcus multilocularis fmrfamide receptor 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma brucei protein kinase, putative 0.0113 0.0276 0.3442
Brugia malayi nuclear receptor RXR 0.0014 0.0005 0.0021
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0192 0.2391
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0071 0.1056
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0079 0.0979
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.011 0.1357
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0021 0.002
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0033 0.0057 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0021 0.0045
Plasmodium falciparum phd finger protein, putative 0.0028 0.0044 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Echinococcus multilocularis sex peptide receptor 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Echinococcus multilocularis pyruvate kinase 0.0036 0.0066 0.0141
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0039 0.0471
Brugia malayi PHD-finger family protein 0.0056 0.012 0.0571
Loa Loa (eye worm) RNA binding protein 0.0068 0.0153 0.0153
Echinococcus multilocularis BC026374 protein (S09 family) 0.0131 0.0326 0.0708
Onchocerca volvulus Putative fad oxidoreductase 0.0305 0.0802 1
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0153 0.0153
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0305 0.0802 1
Schistosoma mansoni acetylcholinesterase 0.0131 0.0326 0.0325
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0349 0.0759
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0072 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0276 0.4098
Loa Loa (eye worm) hypothetical protein 0.0144 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Brugia malayi Tubulin alpha-2 chain 0.0207 0.0532 0.2535
Trypanosoma brucei beta tubulin 0.0258 0.0674 0.84
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.005 0.0232
Echinococcus granulosus methyl CpG binding domain protein 2 0.0037 0.0068 0.0322
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Entamoeba histolytica aldose reductase, putative 0.0052 0.0108 0.1333
Plasmodium falciparum cysteine proteinase falcipain 3 0.0037 0.0067 0.082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0325 0.0325
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.008 0.0079
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0052 0.0108 0.1333
Trichomonas vaginalis tubulin gamma chain, putative 0.0063 0.0138 0.2046
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0021 0.0097
Giardia lamblia Pyruvate kinase 0.0019 0.0017 0.0202
Echinococcus granulosus allatostatin A receptor 0.002 0.0021 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0305 0.0802 0.3821
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0005 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.015 0.0149
Brugia malayi nuclear receptor RXR 0.0016 0.001 0.0044
Toxoplasma gondii alpha-tubulin I, putative 0.0207 0.0532 0.6638
Loa Loa (eye worm) beta-lactamase 0.0039 0.0072 0.0072
Onchocerca volvulus 0.002 0.0021 0.0255
Brugia malayi Tubulin beta chain 0.0082 0.019 0.0903
Schistosoma mansoni opsin-like receptor 0.002 0.0021 0.002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0256 0.0256
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0021 0.0097
Echinococcus granulosus GPCR family 2 0.0033 0.0057 0.027
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0021 0.002
Echinococcus multilocularis lamin 0.003 0.0049 0.0104
Trichomonas vaginalis tubulin, putative 0.0258 0.0674 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0988
Schistosoma mansoni hypothetical protein 0.0033 0.0057 0.0057
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.019 0.2821
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0051 0.0239
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0005 0.0005
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0041 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.005 0.0049
Schistosoma mansoni tubulin subunit alpha 0.0207 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0022 0.0103
Onchocerca volvulus 0.0202 0.052 0.6481
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0067 0.082
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Schistosoma mansoni biogenic amine receptor 0.002 0.0021 0.002
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0035 0.0432
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0015 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0079 0.1176
Echinococcus granulosus voltage gated potassium channel subunit 0.0015 0.0007 0.0029
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0305 0.0802 1
Mycobacterium ulcerans D-amino acid oxidase Aao 0.366 1 1
Brugia malayi AKH receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0052 0.011 0.011
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0021 0.002
Plasmodium falciparum aldehyde reductase, putative 0.0015 0.0007 0.0075
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0066 0.0071
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0071 0.0877
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.002 0.0253
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0079 0.0374
Schistosoma mansoni amine GPCR 0.002 0.0021 0.002
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0131 0.0326 0.0355
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.002 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.005 0.005
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0159 0.0346
Entamoeba histolytica tubulin family protein 0.0258 0.0674 0.8399
Brugia malayi Bromodomain containing protein 0.0166 0.0422 0.2009
Brugia malayi nuclear hormone receptor 0.0014 0.0005 0.0021
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0068 0.0067
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.002 0.0042
Echinococcus granulosus tubulin alpha chain 0.0207 0.0532 0.2535
Echinococcus granulosus beta tubulin 0.0258 0.0674 0.3209
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0073 0.0166 0.0165
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0014 0.0161
Entamoeba histolytica cysteine proteinase 1, putative 0.0019 0.0018 0.021
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Schistosoma mansoni alpha tubulin 0.0207 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.005 0.0106
Echinococcus granulosus mitogen activated protein kinase 3 0.0113 0.0276 0.1313
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0778 0.2098 0.2097
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.002 0.0244
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Brugia malayi tailless protein 0.0014 0.0005 0.0021
Schistosoma mansoni sex comb on midleg homolog 0.0105 0.0253 0.0252
Echinococcus multilocularis acetylcholinesterase 0.0778 0.2098 0.4569
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.003 0.0364
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.005 0.0049
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0305 0.0802 1
Schistosoma mansoni tubulin subunit gamma 0.0145 0.0362 0.0362
Schistosoma mansoni d-amino acid oxidase 0.366 1 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.001
Brugia malayi hypothetical protein 0.0021 0.0023 0.0108
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.005 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0192 0.2391
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.011 0.0266 0.0578
Onchocerca volvulus 0.002 0.0021 0.0255
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Entamoeba histolytica tubulin family protein 0.0258 0.0674 0.8399
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.005 0.0049
Echinococcus multilocularis chromobox protein 1 0.0072 0.0164 0.0356
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Loa Loa (eye worm) tubulin alpha chain 0.0207 0.0532 0.0532
Entamoeba histolytica ABC transporter, putative 0.0021 0.0022 0.0269
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Onchocerca volvulus 0.0037 0.0067 0.082
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.002 0.0243
Echinococcus multilocularis RUN 0.0021 0.0023 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0079 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Brugia malayi tubulin alpha-2 chain 0.0207 0.0532 0.2535
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0021 0.0045
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0021 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Echinococcus multilocularis serotonin receptor 0.002 0.0021 0.0045
Leishmania major cathepsin L-like protease 0.0037 0.0067 0.082
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0266 0.0265
Trichomonas vaginalis aldo-keto reductase, putative 0.0015 0.0007 0.0101
Echinococcus granulosus acetylcholinesterase 0.0778 0.2098 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0072 0.0893
Loa Loa (eye worm) hypothetical protein 0.0084 0.0197 0.0197
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0057 0.027
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.005 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0164 0.2439
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0085 0.1057
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.005 0.0049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0021 0.0045
Echinococcus granulosus neuropeptide receptor 0.002 0.0021 0.0097
Onchocerca volvulus 0.0014 0.0005 0.0055
Echinococcus granulosus SAM and MBT domain containing protein 0.0105 0.0253 0.1202
Echinococcus granulosus Tubulin beta 2C chain 0.0258 0.0674 0.3209
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0072 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0005 0.0021
Onchocerca volvulus 0.0021 0.0023 0.0283
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0159 0.0173
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Schistosoma mansoni myosin xvIII 0.002 0.0021 0.002
Loa Loa (eye worm) oxidoreductase 0.0052 0.0108 0.0108
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0021 0.002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0079 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0077 0.1143
Entamoeba histolytica hypothetical protein 0.0043 0.0085 0.1048
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0325 0.1547
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.003 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0009 0.0127
Plasmodium vivax aldehyde reductase, putative 0.0015 0.0007 0.0075
Echinococcus granulosus tubulin alpha chain 0.0207 0.0532 0.2535
Brugia malayi beta-lactamase 0.0039 0.0072 0.0341
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0015 0.0007 0.0075
Mycobacterium ulcerans cell division protein FtsZ 0.0063 0.0138 0.0137
Brugia malayi Heterochromatin protein 1 0.0072 0.0164 0.078
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0017 0.0013 0.0013
Schistosoma mansoni zinc finger protein 0.0034 0.0058 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.005 0.0232
Loa Loa (eye worm) hypothetical protein 0.0155 0.0392 0.0392
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0021 0.0022 0.0279
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0005 0.0005
Brugia malayi putative neuropeptide receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) bromodomain containing protein 0.0039 0.0072 0.0072
Plasmodium vivax delta tubulin, putative 0.0063 0.0138 0.1711
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0013 0.0001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0041 0.0604
Onchocerca volvulus 0.0105 0.0253 0.3145
Echinococcus granulosus chromobox protein 1 0.0072 0.0164 0.078
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.036 0.5347
Plasmodium falciparum aldo-keto reductase, putative 0.0015 0.0007 0.0075
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0305 0.0802 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.005 0.0232
Schistosoma mansoni chromobox protein 0.0072 0.0164 0.0164
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0021 0.0045
Plasmodium vivax tubulin gamma chain, putative 0.0145 0.0362 0.4511
Trichomonas vaginalis tubulin epsilon chain, putative 0.0207 0.0532 0.7902
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0305 0.0802 0.3821
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0021 0.0045
Schistosoma mansoni pyruvate kinase 0.0036 0.0066 0.0065
Schistosoma mansoni neuroligin 3 (S09 family) 0.0131 0.0326 0.0325
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0071 0.0877
Echinococcus multilocularis mitogen activated protein kinase 3 0.0113 0.0276 0.06
Onchocerca volvulus 0.0025 0.0033 0.0404
Entamoeba histolytica tubulin alpha chain, putative 0.0207 0.0532 0.6635
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0155 0.0391 0.0391
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Onchocerca volvulus 0.002 0.0021 0.0255
Onchocerca volvulus 0.0039 0.0072 0.0893
Schistosoma mansoni zinc finger protein 0.0045 0.0088 0.0088
Echinococcus granulosus aldehyde reductase 0.0037 0.0067 0.0313
Echinococcus granulosus alpha tubulin 0.0207 0.0532 0.2535
Echinococcus multilocularis peregrin 0.0034 0.0058 0.0124
Loa Loa (eye worm) oxidoreductase 0.0052 0.0108 0.0108
Trypanosoma brucei ISWI complex protein 0.0034 0.0058 0.072
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0033 0.0032
Schistosoma mansoni chromobox protein 0.0072 0.0164 0.0164
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0079 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0033 0.0493
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0159 0.0159
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0021 0.0021
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.005 0.0049
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0023 0.0023
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0164 0.0164
Brugia malayi Cathepsin L-like precursor 0.0025 0.0033 0.0154
Schistosoma mansoni lamin 0.003 0.0049 0.0048
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0066 0.0819
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0039 0.0039
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0022 0.0103
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0013 0.0001 0.001
Trichomonas vaginalis tubulin, putative 0.0063 0.0138 0.2046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0072 0.0156
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0015 0.0007 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0071 0.0077
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0063 0.0138 1
Echinococcus multilocularis cysteine protease 0.0037 0.0067 0.0143
Leishmania major cysteine peptidase A (CPA) 0.0037 0.0067 0.082
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0153 0.0153
Onchocerca volvulus 0.002 0.0021 0.0255
Trypanosoma brucei zeta tubulin, putative 0.0063 0.0138 0.1719
Echinococcus multilocularis tubulin subunit beta 0.0258 0.0674 0.1467
Schistosoma mansoni neuropeptide receptor 0.002 0.0021 0.002
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.002 0.0253
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0008 0.0102
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.001 0.0009
Loa Loa (eye worm) dehydrogenase 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0249 0.0648 0.0706
Loa Loa (eye worm) hypothetical protein 0.0089 0.0211 0.0211
Trichomonas vaginalis ornithine decarboxylase, putative 0.0072 0.0164 0.2429
Brugia malayi hypothetical protein 0.0043 0.0085 0.04
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.005 0.0106
Echinococcus multilocularis allatostatin A receptor 0.002 0.0021 0.0045
Echinococcus granulosus serotonin receptor 0.002 0.0021 0.0097
Echinococcus multilocularis Tubulin beta 2C chain 0.0258 0.0674 0.1467
Trypanosoma brucei ABC transporter, putative 0.0021 0.0022 0.0279
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Onchocerca volvulus 0.0052 0.0108 0.1333
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0021 0.0097
Echinococcus granulosus Tubulin beta 2C chain 0.0258 0.0674 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Mycobacterium tuberculosis Conserved protein 0.0015 0.0007 0.0007
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0105 0.0253 0.3145
Onchocerca volvulus 0.002 0.0021 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Giardia lamblia Beta tubulin 0.0258 0.0674 0.8399
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0015 0.0007 0.0101
Leishmania major hypothetical protein, conserved 0.0305 0.0802 1
Trypanosoma brucei oxidoreductase-like protein 0.0013 0.0001 0.001
Onchocerca volvulus 0.002 0.0021 0.0255
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0066 0.0975
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Echinococcus multilocularis mitogen activated protein kinase 0.0113 0.0276 0.06
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0005 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Leishmania major pyruvate kinase 0.0036 0.0066 0.081
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0221 0.1049
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.008 0.5775
Onchocerca volvulus 0.002 0.0021 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0021 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni inositol monophosphatase 0.0042 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0305 0.0802 0.0802
Brugia malayi hypothetical protein 0.0016 0.001 0.0044
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0021 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0018 0.0262
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Mycobacterium leprae Conserved hypothetical protein 0.0037 0.0067 0.0066
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.002
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0033 0.0404
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Brugia malayi Carboxylesterase family protein 0.0131 0.0326 0.155
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0021 0.0045
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0005 0.0021
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Echinococcus multilocularis geminin 0.0183 0.0468 0.1018
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0067 0.0143
Trypanosoma brucei aldo/keto reductase, putative 0.0015 0.0007 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus multilocularis cpg binding protein 0.0037 0.0067 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.001 0.002
Leishmania major delta tubulin, putative 0.0063 0.0138 0.1711
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0349 0.166
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0105 0.0253 0.0252
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.002 0.002
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0021 0.0021
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0349 0.0349
Echinococcus multilocularis pyruvate kinase 0.0019 0.0017 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus acetylcholinesterase 0.0778 0.2098 1
Schistosoma mansoni tubulin subunit delta 0.0063 0.0138 0.0137
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0143 0.0358 0.0358
Schistosoma mansoni sex comb on midleg homolog 0.0105 0.0253 0.0252
Trypanosoma brucei beta tubulin 0.0258 0.0674 0.84
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Onchocerca volvulus 0.002 0.0021 0.0255
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.03 0.03
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.005 0.0049
Leishmania major cathepsin L-like protease 0.0083 0.0192 0.2391
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.005 0.005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0079 0.0979
Brugia malayi Carboxylesterase family protein 0.0131 0.0326 0.155
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0021 0.0097
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0113 0.0276 0.3442
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.0293 0.1391
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Plasmodium falciparum tubulin beta chain 0.0258 0.0674 0.8399
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Loa Loa (eye worm) tubulin beta-1 chain 0.0258 0.0674 0.0674
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0021 0.0045
Schistosoma mansoni lamin 0.003 0.0049 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0349 0.166
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0072 0.0078
Echinococcus multilocularis polycomb protein SCMH1 0.0105 0.0253 0.0549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.001 0.0044
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Echinococcus multilocularis aldehyde reductase 0.0037 0.0067 0.0143
Schistosoma mansoni hypothetical protein 0.0033 0.0057 0.0057
Schistosoma mansoni loxhd1 0.0021 0.0023 0.0023
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.3355 0.9164 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0018 0.021
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0057 0.027
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0044 0.0044
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0124 0.0124
Brugia malayi Cytochrome P450 family protein 0.0027 0.0039 0.018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Brugia malayi G-protein coupled receptor 0.002 0.0021 0.0097
Onchocerca volvulus 0.0131 0.0326 0.4057
Brugia malayi Carboxylesterase family protein 0.0778 0.2098 1
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0041 0.0087
Loa Loa (eye worm) hypothetical protein 0.003 0.0047 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0021 0.0097
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0022 0.0047
Brugia malayi beta-lactamase family protein 0.0039 0.0072 0.0341
Loa Loa (eye worm) fibroinase 0.0037 0.0067 0.0067
Onchocerca volvulus 0.002 0.0021 0.0255
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0067 0.082
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0072 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.002 0.0244
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0071 0.0071
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0005 0.0004
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0153 0.0333
Trypanosoma brucei zeta tubulin 0.0063 0.0138 0.1719
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0085 0.1269
Echinococcus multilocularis Tubulin beta 2C chain 0.0258 0.0674 0.1467
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0018 0.021
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0325 0.4056
Trichomonas vaginalis aldo/keto reductase, putative 0.0052 0.0108 0.1598
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0125 0.0308 0.4572
Echinococcus granulosus tubulin epsilon chain 0.0145 0.0362 0.1724
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.003 0.0364
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0305 0.0802 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.003 0.0029
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0325 0.0354
Chlamydia trachomatis D-amino acid dehydrogenase 0.0305 0.0802 1
Brugia malayi PHD-finger family protein 0.0028 0.0044 0.0204
Brugia malayi GnHR receptor homolog 0.002 0.0021 0.0097
Giardia lamblia Aldose reductase 0.0052 0.0108 0.1333
Echinococcus granulosus neuroligin 0.0131 0.0326 0.155
Onchocerca volvulus 0.0023 0.003 0.0364
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0066 0.0819
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0021 0.0097
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0052 0.0108 0.1598
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Schistosoma mansoni adenoreceptor 0.002 0.0021 0.002
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0005 0.0021
Schistosoma mansoni alpha tubulin 0.0207 0.0532 0.0532
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0021 0.0045
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0021 0.0021
Trichomonas vaginalis aldo/keto reductase, putative 0.0052 0.0108 0.1598
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Trypanosoma brucei alpha tubulin 0.0207 0.0532 0.6638
Mycobacterium ulcerans lipase LipD 0.0039 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.005 0.0106
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) tubulin alpha 2 0.0062 0.0136 0.0136
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0113 0.0276 0.3436
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0021 0.0022 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0052 0.0108 0.1598
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Schistosoma mansoni hypothetical protein 0.0033 0.0057 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.005 0.005
Echinococcus multilocularis pyruvate kinase 0.0036 0.0066 0.0141
Loa Loa (eye worm) tubulin alpha 2 0.0144 0.036 0.036
Schistosoma mansoni amine GPCR 0.002 0.0021 0.002
Echinococcus multilocularis para nitrobenzyl esterase 0.0131 0.0326 0.0708
Loa Loa (eye worm) hypothetical protein 0.0033 0.0057 0.0057
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0005 0.0021
Echinococcus granulosus chromobox protein 1 0.0072 0.0164 0.078
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0063 0.0138 0.1719
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.03 0.03
Giardia lamblia Ornithine decarboxylase 0.0202 0.052 0.6481
Onchocerca volvulus 0.0037 0.0067 0.082
Onchocerca volvulus 0.003 0.0049 0.0595
Leishmania major hypothetical protein, conserved 0.0052 0.011 0.1357
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0068 0.0068
Entamoeba histolytica alcohol dehydrogenase, putative 0.0015 0.0007 0.0075
Echinococcus granulosus pyruvate kinase 0.0019 0.0017 0.0077
Loa Loa (eye worm) carboxylesterase 0.0778 0.2098 0.2098
Echinococcus granulosus dnaJ subfamily B 0.0442 0.1178 0.5615
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Schistosoma mansoni tubulin subunit alpha 0.0207 0.0532 0.0532
Trichomonas vaginalis tubulin beta chain, putative 0.0258 0.0674 1
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.0305 0.0802 0.0801
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0266 0.0265
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0305 0.0802 1
Mycobacterium ulcerans hypothetical protein 0.0039 0.0072 0.0072
Plasmodium vivax unspecified product 0.0019 0.0018 0.021
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Echinococcus multilocularis neuropeptide receptor 0.002 0.0021 0.0045
Giardia lamblia Alpha-tubulin 0.0207 0.0532 0.6635
Echinococcus multilocularis aldo keto reductase 0.0052 0.0108 0.0233
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Leishmania major cathepsin L-like protease 0.0037 0.0067 0.082
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0039 0.0471
Echinococcus granulosus microtubule associated protein 2 0.0773 0.2085 0.9941
Schistosoma mansoni cpg binding protein 0.0031 0.0051 0.005
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0021 0.0045
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Plasmodium falciparum cysteine proteinase falcipain 1 0.0019 0.0018 0.021
Schistosoma mansoni hypothetical protein 0.0183 0.0468 0.0467
Onchocerca volvulus 0.0131 0.0326 0.4057
Brugia malayi Pre-SET motif family protein 0.0226 0.0585 0.2784
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0071 0.0159 0.1975
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0128 0.0604
Brugia malayi RE15519p 0.002 0.0021 0.0097
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0021 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0133 0.033 0.1569
Trichomonas vaginalis aldo/keto reductase, putative 0.0052 0.0108 0.1598
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.001
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0022 0.0022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.002 0.0243
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0067
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0144 0.1801
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0005 0.0021
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0131 0.0326 0.4837
Schistosoma mansoni opsin-like receptor 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0066
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0079 0.0374
Loa Loa (eye worm) hypothetical protein 0.0105 0.0253 0.0253
Echinococcus multilocularis tubulin beta 1 chain 0.0258 0.0674 0.1467
Leishmania major hypothetical protein, conserved 0.0305 0.0802 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0021 0.002
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0022 0.0103
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0071 0.0335
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0066 0.0309
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0072 0.0072
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0017 0.0202
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0266 0.0265
Loa Loa (eye worm) hypothetical protein 0.0207 0.0532 0.0532
Schistosoma mansoni biogenic amine receptor 0.002 0.0021 0.002
Echinococcus granulosus tubulin alpha 3 chain 0.0207 0.0532 0.2535
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0005 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.005 0.0232
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Brugia malayi beta-tubulin, identical 0.0258 0.0674 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Echinococcus granulosus hypothetical protein 0.002 0.0021 0.0097
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.002
Onchocerca volvulus 0.002 0.0021 0.0255
Echinococcus multilocularis fmrfamide receptor 0.002 0.0021 0.0045
Echinococcus granulosus lamin dm0 0.003 0.0049 0.0227
Toxoplasma gondii oxidoreductase, putative 0.0013 0.0001 0.001
Onchocerca volvulus 0.0037 0.0067 0.082
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.008 0.0997
Onchocerca volvulus 0.0014 0.0005 0.0055
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0021 0.0097
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0153 0.0153
Brugia malayi Doublecortin family protein 0.0021 0.0023 0.0108
Echinococcus granulosus BC026374 protein S09 family 0.0131 0.0326 0.155
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0159 0.0159
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0305 0.0802 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Plasmodium vivax SET domain protein, putative 0.0033 0.0056 0.0689
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0023 0.0283
Mycobacterium tuberculosis Conserved protein 0.0039 0.0072 0.0078
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.008 0.1187
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0021 0.0097
Brugia malayi tubulin alpha chain - mouse 0.0207 0.0532 0.2535
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0052 0.0108 0.1333
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Echinococcus multilocularis GPCR, family 2 0.0033 0.0057 0.0123
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.005 0.0106
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0021 0.002
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.003 0.0367
Trichomonas vaginalis tubulin epsilon chain, putative 0.0258 0.0674 1
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0018 0.021
Loa Loa (eye worm) tubulin beta-2A chain 0.0258 0.0674 0.0674
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0021 0.002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.002 0.0243
Brugia malayi CXXC zinc finger family protein 0.0031 0.0051 0.0238
Schistosoma mansoni amine GPCR 0.002 0.0021 0.002
Plasmodium falciparum alpha tubulin 2 0.0207 0.0532 0.6635
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0021 0.0097
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0305 0.0802 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0023
Plasmodium falciparum alpha tubulin 1 0.0207 0.0532 0.6635
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0073 0.0166 0.2463
Brugia malayi Dopamine receptor 0.002 0.0021 0.0097
Echinococcus granulosus peregrin 0.0034 0.0058 0.0272
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0018 0.022
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0072 0.1075
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0153 0.0153
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0052 0.0108 0.051
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Trypanosoma brucei ATP-binding cassette protein, putative 0.0021 0.0022 0.0279
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni BC026374 protein (S09 family) 0.0131 0.0326 0.0325
Mycobacterium ulcerans hypothetical protein 0.0015 0.0007 0.0006
Brugia malayi Bromodomain containing protein 0.0034 0.0058 0.0272
Echinococcus multilocularis peroxisome assembly protein 26 0.0207 0.0532 0.1159
Schistosoma mansoni neuropeptide receptor 0.002 0.0021 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0067 0.0066
Echinococcus multilocularis hypothetical protein 0.0207 0.0532 0.1159
Echinococcus multilocularis Glycoside hydrolase, family 27 0.011 0.0266 0.0578
Trypanosoma brucei aldo-keto reductase, putative 0.0052 0.0108 0.1342
Giardia lamblia GTOR 0.002 0.002 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus granulosus neuropeptide s receptor 0.002 0.0021 0.0097
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0007 0.0014
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0021 0.0021
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0049 0.0227
Mycobacterium tuberculosis Conserved protein 0.0039 0.0072 0.0078
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0349 0.166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0442 0.1178 0.1178
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.003
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0159 0.0159
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0072 0.1075
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0079 0.0979
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Brugia malayi Tubulin alpha chain 0.0063 0.0138 0.0654
Onchocerca volvulus 0.0131 0.0326 0.4057
Toxoplasma gondii ABC1 family protein 0.0039 0.0072 0.0903
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0013 0.0001 0.001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Echinococcus multilocularis pyruvate kinase 0.0029 0.0045 0.0095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0072 0.0072
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Plasmodium vivax tubulin alpha chain, putative 0.0207 0.0532 0.6635
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0066 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0013 0.0001 0.001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0021 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Echinococcus granulosus Tubulin alpha 1 chain 0.0207 0.0532 0.2535
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0044 0.0093
Onchocerca volvulus 0.0031 0.005 0.0608
Brugia malayi jmjC domain containing protein 0.004 0.0076 0.036
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0005 0.0004
Entamoeba histolytica hypothetical protein 0.0043 0.0085 0.1048
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0066 0.0975
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Toxoplasma gondii aldo-keto reductase 0.0015 0.0007 0.0085
Schistosoma mansoni opsin-like receptor 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0018 0.0262
Schistosoma mansoni neuropeptide receptor 0.002 0.0021 0.002
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0072 0.0893
Loa Loa (eye worm) tubulin beta-4 chain 0.0258 0.0674 0.0674
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0021 0.002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0005 0.0021
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0113 0.0276 0.3436
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0305 0.0802 0.3821
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0019 0.0018 0.021
Loa Loa (eye worm) alpha-tubulin 0.0207 0.0532 0.0532
Echinococcus multilocularis aldo keto reductase 0.0052 0.0108 0.0233
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0018 0.0015 0.0065
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0079 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0021 0.0045
Brugia malayi Pre-SET motif family protein 0.0033 0.0056 0.0263
Onchocerca volvulus 0.002 0.0021 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0138 0.2046
Schistosoma mansoni microtubule-associated protein tau 0.0773 0.2085 0.2085
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.005 0.0106
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.005 0.0232
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.003 0.0064
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trypanosoma cruzi cruzipain precursor, putative 0.0083 0.0192 0.2391
Brugia malayi Dopamine receptor protein 2 0.002 0.0021 0.0097
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0305 0.0802 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0067 0.0143
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0145 0.0362 0.4517
Loa Loa (eye worm) oxidoreductase 0.0052 0.0108 0.0108
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0066 0.081
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Echinococcus granulosus beta tubulin 0.0258 0.0674 0.3209
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0305 0.0802 0.0801
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0305 0.0802 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0021 0.0097
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0018 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.005 0.0232
Leishmania major hypothetical protein, conserved 0.0039 0.0072 0.0893
Echinococcus multilocularis pyruvate kinase 0.0019 0.0017 0.0035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Echinococcus granulosus pyruvate kinase 0.0019 0.0017 0.0077
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.003 0.0029
Brugia malayi CHD4 protein 0.0018 0.0015 0.0065
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0256 0.1215
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0021 0.0097
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0021 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Schistosoma mansoni nuclear receptor 0.0014 0.0005 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0021 0.0045
Schistosoma mansoni hypothetical protein 0.0045 0.009 0.0089
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0056 0.0699
Chlamydia trachomatis pyruvate kinase 0.0036 0.0066 0.066
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.011 0.1357
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.0305 0.0802 0.0801
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Loa Loa (eye worm) hypothetical protein 0.0119 0.0293 0.0293
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0113 0.0276 0.3436
Trichomonas vaginalis tubulin gamma chain, putative 0.0145 0.0362 0.5377
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Echinococcus granulosus endonuclease exonuclease phosphatase 0.042 0.1118 0.533
Mycobacterium tuberculosis Diaminopimelate decarboxylase LysA (DAP decarboxylase) 0.0202 0.052 0.0567
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0018 0.008
Brugia malayi Inositol-1 0.0042 0.008 0.0378
Echinococcus granulosus tubulin delta chain 0.0063 0.0138 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0101
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0005 0.0004
Echinococcus granulosus tubulin alpha 1C chain 0.0207 0.0532 0.2535
Trypanosoma brucei alpha tubulin 0.0207 0.0532 0.6638
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.003 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0044 0.0533
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Echinococcus granulosus tubulin alpha chain 0.0207 0.0532 0.2535
Plasmodium falciparum tubulin delta chain, putative 0.0063 0.0138 0.1711
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Loa Loa (eye worm) pyridoxal-dependent decarboxylase 0.0202 0.052 0.052
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.005 0.005
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni NAD dehydrogenase 0.0305 0.0802 0.0801
Onchocerca volvulus 0.0021 0.0023 0.0283
Loa Loa (eye worm) alpha-tubulin 0.0207 0.0532 0.0532
Brugia malayi NADH-dependent xylose reductase 0.0015 0.0007 0.0029
Loa Loa (eye worm) tubulin alpha-2 chain 0.0207 0.0532 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Schistosoma mansoni nuclear hormone receptor 0.0031 0.005 0.0049
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0052 0.0108 0.051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0066 0.0066
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0305 0.0802 1
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0305 0.0802 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0258 0.0674 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.002 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.005 0.0232
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0068 0.0068
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0079 0.1176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Giardia lamblia Epsilon tubulin 0.0063 0.0138 0.1711
Mycobacterium ulcerans beta-lactamase 0.0039 0.0072 0.0072
Toxoplasma gondii hypothetical protein 0.0305 0.0802 1
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0021 0.0045
Echinococcus multilocularis tubulin alpha chain 0.0207 0.0532 0.1159
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0138 0.2046
Onchocerca volvulus 0.0052 0.0108 0.1333
Loa Loa (eye worm) BEN-1 protein 0.0258 0.0674 0.0674
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0153 0.0153
Mycobacterium ulcerans carboxylesterase, LipT 0.0131 0.0326 0.0325
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.008 0.0378
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Giardia lamblia Pyruvate kinase 0.0036 0.0066 0.081
Trypanosoma cruzi cysteine protease, putative 0.0019 0.0018 0.021
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0305 0.0802 0.0801
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0017
Schistosoma mansoni bromodomain containing protein 0.0141 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0095 0.0227 0.0227
Plasmodium vivax vivapain-3 0.0019 0.0018 0.021
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0021 0.0097
Echinococcus multilocularis tubulin alpha chain 0.0207 0.0532 0.1159
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Echinococcus granulosus g protein coupled receptor 0.002 0.0021 0.0097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0079 0.0182 0.0395
Giardia lamblia Kinase, CMGC MAPK 0.0113 0.0276 0.3436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.003 0.0364
Loa Loa (eye worm) dehydrogenase 0.0013 0.0001 0.0001
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0144 0.036 0.036
Onchocerca volvulus 0.0052 0.0108 0.1333
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0021 0.0097
Echinococcus multilocularis chromobox protein 1 0.0072 0.0164 0.0356
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0023 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0016 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0072 0.1075
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.0293 0.0636
Echinococcus granulosus somatostatin receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.007 0.0159 0.0159
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0325 0.405
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0305 0.0802 0.1746
Brugia malayi hypothetical protein 0.0016 0.001 0.0044
Trypanosoma brucei prostaglandin f synthase 0.0052 0.0108 0.1342
Schistosoma mansoni alpha tubulin 0.0207 0.0532 0.0532
Trypanosoma cruzi aldo/keto reductase, putative 0.0015 0.0007 0.0075
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.003 0.0364
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.005 0.0232
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0021 0.002
Trypanosoma cruzi epsilon tubulin, putative 0.0145 0.0362 0.4511
Echinococcus granulosus RUN 0.0021 0.0023 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0207 0.0532 0.7902
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus granulosus tubulin alpha 0.0145 0.0362 0.1724
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0305 0.0802 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.0585 0.0585
Echinococcus granulosus cathepsin l1 0.0037 0.0067 0.0313
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0013 0.0001 0.001
Brugia malayi ecdysone receptor 0.0014 0.0005 0.0021
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0326 0.0325
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0325 0.0707
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.002 0.0243
Trypanosoma brucei tubulin gamma chain 0.0145 0.0362 0.4517
Trichomonas vaginalis diaminopimelate decarboxylase, putative 0.0202 0.052 0.7719
Echinococcus granulosus cpg binding protein 0.0037 0.0067 0.0316
Brugia malayi SET domain containing protein 0.0014 0.0003 0.0012
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0022 0.0022
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.002 0.0243
Echinococcus granulosus aldo keto reductase 0.0052 0.0108 0.051
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0997
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.042 0.1118 0.2436
Brugia malayi Serotonin receptor 0.002 0.0021 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0276 0.4098
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.0305 0.0802 0.0801
Schistosoma mansoni thyroid hormone receptor 0.0031 0.005 0.0049
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0057 0.0057
Loa Loa (eye worm) inositol-1 0.0042 0.008 0.008
Trypanosoma cruzi alpha tubulin, putative 0.0207 0.0532 0.6635
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.005 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus tar DNA binding protein 0.0068 0.0153 0.0728
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0001 0.001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.001 0.0009
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.0018 0.008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0113 0.0276 0.0276
Onchocerca volvulus 0.0037 0.0067 0.082
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0005 0.0021
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0029
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.008 0.1187
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.002 0.0093
Echinococcus granulosus mitogen activated protein kinase 0.0113 0.0276 0.1313
Schistosoma mansoni tubulin subunit beta 0.0063 0.0138 0.0137
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0079 0.0979
Mycobacterium leprae PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE) 0.0078 0.018 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.005 0.0232
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0018 0.021
Trypanosoma brucei epsilon tubulin 0.0145 0.0362 0.4517
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0305 0.0802 1
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Loa Loa (eye worm) carboxylesterase 0.0131 0.0326 0.0326
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0056 0.012
Brugia malayi Bromodomain containing protein 0.0084 0.0196 0.0932
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0021 0.0045
Schistosoma mansoni cpg binding protein 0.0037 0.0067 0.0066
Echinococcus multilocularis Tubulin beta 2C chain 0.0258 0.0674 0.1467
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Brugia malayi larval opioid receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium ulcerans oxidoreductase 0.0052 0.0108 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0021 0.0097
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0066 0.081
Loa Loa (eye worm) acetylcholinesterase 1 0.0778 0.2098 0.2098
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.005 0.0049
Treponema pallidum cell division protein FtsZ 0.0063 0.0138 1
Echinococcus multilocularis aldo keto reductase 0.0052 0.0108 0.0233
Brugia malayi AMP-binding enzyme family protein 0.0023 0.003 0.0139
Onchocerca volvulus 0.0039 0.0072 0.0893
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0067 0.082
Echinococcus multilocularis dnaJ subfamily B 0.0442 0.1178 0.2566
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0021 0.0045
Leishmania major cathepsin L-like protease 0.0037 0.0067 0.082
Echinococcus granulosus neuropeptide receptor 0.002 0.0021 0.0097
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0258 0.0674 0.1467
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni potassium channel beta 0.0015 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0005 0.0004
Trypanosoma brucei alpha tubulin, putative 0.0082 0.019 0.237
Trichomonas vaginalis spcc417.12 protein, putative 0.0131 0.0326 0.4837
Echinococcus granulosus zinc finger protein 0.0045 0.0088 0.0418
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.002 0.0243
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Echinococcus granulosus cysteine protease 0.0019 0.0018 0.008
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0159 0.0756
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0079 0.0374
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.001
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0067 0.0313
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0021 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0006 0.0011
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0067 0.0313
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Trypanosoma cruzi aldo-keto reductase 0.0052 0.0108 0.1333
Leishmania major prostaglandin f synthase, putative 0.0052 0.0108 0.1333
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Leishmania major cathepsin L-like protease 0.0037 0.0067 0.082
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus multilocularis musashi 0.003 0.0049 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0044 0.0543
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0077 0.0951
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0266 0.0265
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0051 0.0051
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0305 0.0802 1
Schistosoma mansoni intermediate filament proteins 0.003 0.0049 0.0048
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0349 0.0348
Entamoeba histolytica ornithine decarboxylase, putative 0.0202 0.052 0.6481
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0066 0.081
Echinococcus multilocularis g protein coupled receptor 0.002 0.0021 0.0045
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0076 0.036
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0057 0.027
Echinococcus granulosus hypothetical protein 0.0052 0.0108 0.051
Echinococcus multilocularis tubulin alpha 1C chain 0.0207 0.0532 0.1159
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.005 0.0608
Loa Loa (eye worm) hypothetical protein 0.0041 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.005 0.005
Brugia malayi Tubulin gamma chain 0.0145 0.0362 0.1724
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.005 0.0232
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Mycobacterium tuberculosis Conserved protein 0.0039 0.0072 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0007
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0037 0.0067 0.082
Echinococcus multilocularis Tubulin alpha 1 chain 0.0207 0.0532 0.1159
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0159 0.0756
Entamoeba histolytica aldose reductase, putative 0.0052 0.0108 0.1333
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0066 0.081
Echinococcus multilocularis SAM and MBT domain containing protein 0.0105 0.0253 0.0549
Brugia malayi nuclear hormone receptor 0.0031 0.005 0.0232
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0221 0.0479
Schistosoma mansoni amine GPCR 0.002 0.0021 0.002
Loa Loa (eye worm) oxidoreductase 0.0052 0.0108 0.0108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Onchocerca volvulus 0.0052 0.0108 0.1333
Echinococcus granulosus Tubulin beta 2C chain 0.0258 0.0674 0.3209
Trichomonas vaginalis aldo-keto reductase, putative 0.0015 0.0007 0.0101
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0085 0.0084
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0021 0.0021
Brugia malayi nuclear receptor NHR-88 0.0031 0.005 0.0232
Trypanosoma brucei epsilon tubulin 0.0145 0.0362 0.4517
Echinococcus granulosus polycomb protein SCMH1 0.0105 0.0253 0.1202
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0021 0.0021
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Loa Loa (eye worm) tubulin beta chain 0.0063 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1687 0.459 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.002 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0021 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.002 0.0093
Schistosoma mansoni neuropeptide receptor 0.002 0.0021 0.002
Loa Loa (eye worm) CHromoDomain protein family member 0.0018 0.0015 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.003 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0018 0.022
Schistosoma mansoni aldo-keto reductase 0.0052 0.0108 0.0107
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trypanosoma brucei alpha tubulin 0.0207 0.0532 0.6638
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0017
Onchocerca volvulus 0.0037 0.0067 0.082
Echinococcus granulosus FTZ F1 alpha 0.0031 0.005 0.0232
Echinococcus multilocularis tubulin delta chain 0.0063 0.0138 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Schistosoma mansoni fad oxidoreductase 0.0305 0.0802 0.0801
Brugia malayi TAR-binding protein 0.0068 0.0153 0.0728
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus multilocularis serotonin receptor 0.002 0.0021 0.0045
Onchocerca volvulus 0.0082 0.019 0.2362
Toxoplasma gondii melibiase subfamily protein 0.011 0.0266 0.3317
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi nuclear receptor NHR-67 0.0014 0.0005 0.0021
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0021 0.0097
Schistosoma mansoni hypothetical protein 0.0028 0.0044 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0079 0.1176
Brugia malayi neuropeptide F receptor 0.002 0.0021 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0257 0.067 0.994
Entamoeba histolytica alcohol dehydrogenase, putative 0.0015 0.0007 0.0075
Plasmodium vivax tubulin beta chain, putative 0.0258 0.0674 0.8399
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0071 0.0877
Onchocerca volvulus 0.0032 0.0053 0.0651
Schistosoma mansoni ap endonuclease 0.0038 0.0071 0.007
Echinococcus multilocularis muscleblind protein 0.0155 0.0392 0.0852
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0392 0.0852
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.002
Brugia malayi Melatonin receptor type 1A 0.002 0.0021 0.0097
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0079 0.0979
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0066 0.0309
Toxoplasma gondii alpha tubulin TUBA1 0.0207 0.0532 0.6638
Mycobacterium leprae Probable lipase LipE 0.0039 0.0072 0.0072
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0071 0.0877
Mycobacterium tuberculosis Cell division protein FtsZ 0.0063 0.0138 0.015
Brugia malayi Cathepsin L-like precursor 0.0025 0.0033 0.0154
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0153 0.0728
Echinococcus multilocularis beta tubulin 0.0258 0.0674 0.1467
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0057 0.027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.005 0.0232
Brugia malayi AMP-binding enzyme family protein 0.0023 0.003 0.0139
Brugia malayi MH2 domain containing protein 0.0122 0.03 0.1426
Leishmania major hypothetical protein, conserved 0.0034 0.0058 0.0711
Onchocerca volvulus 0.002 0.0021 0.0255
Entamoeba histolytica aldose reductase, putative 0.0052 0.0108 0.1333
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0305 0.0802 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0021 0.0097
Echinococcus multilocularis Tubulin alpha 1 chain 0.0207 0.0532 0.1159
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Echinococcus multilocularis tubulin gamma 1 chain 0.0145 0.0362 0.0788
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0113 0.0276 0.3442
Leishmania major zeta tubulin, putative 0.0063 0.0138 0.1711
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Trypanosoma cruzi epsilon tubulin, putative 0.0145 0.0362 0.4511
Echinococcus multilocularis tubulin alpha 1C chain 0.0207 0.0532 0.1159
Brugia malayi neuropeptide F receptor 0.002 0.0021 0.0097
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0071 0.0877
Plasmodium falciparum ABC transporter G family member 2 0.0021 0.0022 0.0269
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Giardia lamblia Delta tubulin 0.0063 0.0138 0.1711
Plasmodium vivax vivapain-1 0.0019 0.0018 0.021
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0001 0.001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0005 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0276 0.0275
Onchocerca volvulus 0.0131 0.0326 0.4057
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0057 0.0123
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.003 0.0029
Trypanosoma cruzi tubulin delta chain 0.0063 0.0138 0.1711
Echinococcus granulosus sex peptide receptor 0.002 0.0021 0.0097
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Brugia malayi ABC transporter family protein 0.0018 0.0014 0.0062
Trichomonas vaginalis tubulin epsilon chain, putative 0.0063 0.0138 0.2046
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0035 0.0035
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0021 0.002
Entamoeba histolytica hypothetical protein 0.0027 0.0041 0.0498
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0021 0.0097
Brugia malayi hypothetical protein 0.0052 0.011 0.0519
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0071 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0045 0.0661
Loa Loa (eye worm) hypothetical protein 0.0072 0.0164 0.0164
Brugia malayi intermediate filament protein 0.003 0.0049 0.0227
Leishmania major cytochrome p450-like protein 0.0027 0.0039 0.0471
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Loa Loa (eye worm) hypothetical protein 0.0049 0.0099 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0192 0.2391
Plasmodium vivax vivapain-2 0.0037 0.0067 0.082
Schistosoma mansoni thyroid hormone receptor 0.0031 0.005 0.0049
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0013 0.0001 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.002 0.0253
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0072 0.0072
Brugia malayi Pyridoxal-dependent decarboxylase, pyridoxal binding domain containing protein 0.0202 0.052 0.2477
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.002 0.0253
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0072 0.0072
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0014 0.0013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0072 0.0078
Echinococcus granulosus aldo keto reductase 0.0052 0.0108 0.051
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0023 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Loa Loa (eye worm) hypothetical protein 0.0041 0.0079 0.0079
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.011 0.1357
Loa Loa (eye worm) cysteine protease 0.0037 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0073 0.0166 0.0166
Brugia malayi Tubulin alpha-2 chain 0.0207 0.0532 0.2535
Echinococcus multilocularis cathepsin L 0.0019 0.0018 0.0037
Trypanosoma cruzi tubulin gamma chain 0.0145 0.0362 0.4511
Loa Loa (eye worm) ctsf protein 0.0037 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0125 0.0308 0.0308
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0168 0.0167
Plasmodium falciparum tubulin gamma chain 0.0145 0.0362 0.4511
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.002 0.0243
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0159 0.198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.005 0.0106
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Schistosoma mansoni histamine h1 receptor 0.002 0.0021 0.002
Echinococcus granulosus Tubulin alpha 1 chain 0.0207 0.0532 0.2535
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0131 0.0326 0.0355
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0013 0.0001 0.001
Echinococcus granulosus tubulin gamma 1 chain 0.0145 0.0362 0.1724
Plasmodium falciparum tubulin epsilon chain, putative 0.0145 0.0362 0.4511
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0079 0.0171
Schistosoma mansoni inositol monophosphatase 0.0042 0.008 0.0079
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0066 0.0066
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.005 0.0232
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.011 0.0266 0.1265
Brugia malayi MAP kinase sur-1 0.0113 0.0276 0.1313
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0202 0.052 0.6481
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.0293 0.1391
Brugia malayi chromobox protein homolog 3 0.0041 0.0077 0.0363
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0072 0.1075
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.005 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.005 0.0608
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Loa Loa (eye worm) tubulin alpha-3 chain 0.0125 0.0308 0.0308
Leishmania major epsilon tubulin, putative 0.0145 0.0362 0.4511
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0072 0.0078
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0018 0.008
Echinococcus granulosus tubulin beta 4A class IVa 0.0258 0.0674 0.3209
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0305 0.0802 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0023
Echinococcus multilocularis tubulin alpha 3 chain 0.0207 0.0532 0.1159
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Echinococcus granulosus jumonji domain containing protein 0.004 0.0074 0.0349
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0005 0.001
Onchocerca volvulus 0.0052 0.0108 0.1333
Brugia malayi cathepsin L-like precursor 0.0025 0.0033 0.0154
Loa Loa (eye worm) tubulin gamma chain 0.0145 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0349 0.0348
Echinococcus granulosus aldo keto reductase 0.0052 0.0108 0.051
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.011 0.1366
Leishmania major gamma-tubulin 0.0145 0.0362 0.4511
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0071 0.0877
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Onchocerca volvulus 0.0037 0.0067 0.082
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.005 0.0232
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0021 0.0045
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0052 0.0108 0.1598
Onchocerca volvulus 0.002 0.0021 0.0255
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0021 0.002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0052 0.0108 0.051
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus lamin 0.003 0.0049 0.0227
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.003 0.0364
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.019 0.2821
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Schistosoma mansoni polycystin 1-related 0.0021 0.0023 0.0023
Echinococcus multilocularis aldo keto reductase 0.0052 0.0108 0.0233
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0079 0.0988
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0037 0.0068 0.0147
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Trypanosoma cruzi zeta tubulin, putative 0.0063 0.0138 0.1711
Trichomonas vaginalis tubulin alpha chain, putative 0.0258 0.0674 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.002 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0021 0.002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0023 0.0049
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0131 0.0326 0.155
Loa Loa (eye worm) intermediate filament protein 0.003 0.0049 0.0049
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0044 0.0543
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.005 0.0232
Brugia malayi hypothetical protein 0.0143 0.0358 0.1704
Echinococcus granulosus tubulin alpha chain 0.0207 0.0532 0.2535
Brugia malayi alpha-tubulin 0.0207 0.0532 0.2535
Schistosoma mansoni hypothetical protein 0.0183 0.0468 0.0467
Loa Loa (eye worm) hypothetical protein 0.0778 0.2098 0.2098
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0001 0.001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0128 0.0276
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.001 0.0044
Loa Loa (eye worm) oxidoreductase 0.0052 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0305 0.0802 0.0802
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0039 0.0038
Trichomonas vaginalis ornithine decarboxylase, putative 0.0202 0.052 0.7719
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Brugia malayi nuclear receptor NHR-88 0.0014 0.0005 0.0021
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0164 0.0778
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0052 0.0108 0.051
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.003 0.0364
Echinococcus granulosus pyruvate kinase 0.0036 0.0066 0.0309
Plasmodium vivax tubulin epsilon chain, putative 0.0145 0.0362 0.4511
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Toxoplasma gondii beta tubulin 0.0258 0.0674 0.84
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.008 0.0988
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.0305 0.0802 0.0801
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0017 0.0259
Leishmania major cathepsin L-like protease 0.0037 0.0067 0.082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0021 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Trypanosoma cruzi ABC transporter, putative 0.0021 0.0022 0.0269
Leishmania major ornithine decarboxylase, putative 0.0202 0.052 0.6481
Brugia malayi Carboxylesterase family protein 0.0131 0.0326 0.155
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0001 0.001
Schistosoma mansoni rab6-interacting 0.0021 0.0023 0.0023
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0066 0.081
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0325 0.0325
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0041 0.0498
Echinococcus multilocularis tubulin alpha chain 0.0207 0.0532 0.1159
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0276 0.3436
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.005 0.0232
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0005 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0018
Schistosoma mansoni lipoxygenase 0.0021 0.0023 0.0023
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0013 0.0001 0.001
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0072 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0153 0.0153
Echinococcus multilocularis Tubulin alpha 1 chain 0.0207 0.0532 0.1159
Echinococcus granulosus Tubulin beta 2C chain 0.0258 0.0674 0.3209
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0072 0.1075
Giardia lamblia Beta tubulin 0.0258 0.0674 0.8399
Brugia malayi Cell division protein ftsZ 0.0063 0.0138 0.0654
Trichomonas vaginalis tubulin beta chain, putative 0.0207 0.0532 0.7902
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.008 0.0173
Onchocerca volvulus 0.0031 0.0051 0.0624
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0072 0.0072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0011
Onchocerca volvulus 0.002 0.0021 0.0255
Leishmania major pyruvate kinase 0.0036 0.0066 0.081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0276 0.4098
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0052 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus multilocularis microtubule associated protein 2 0.0773 0.2085 0.4542
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0045 0.0661
Schistosoma mansoni aldo-keto reductase 0.0052 0.0108 0.0107
Leishmania major aldo-keto reductase-like protein 0.0052 0.0108 0.1333
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma brucei alpha tubulin 0.0207 0.0532 0.6638
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0067 0.0313
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0076 0.0075
Echinococcus granulosus peroxisome assembly protein 26 0.0207 0.0532 0.2535
Loa Loa (eye worm) DR-78 0.0014 0.0005 0.0005
Toxoplasma gondii cathepsin CPL 0.0037 0.0067 0.083
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0015 0.0014
Toxoplasma gondii beta-tubulin, putative 0.0258 0.0674 0.84
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0015 0.0007 0.0075
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0039 0.048
Echinococcus multilocularis tubulin alpha 0.0145 0.0362 0.0788
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0018 0.021
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0021 0.0097
Mycobacterium leprae cell division protein FtsZ 0.0063 0.0138 0.0137
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0202 0.052 0.6481
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.0106 0.023
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0068 0.0073
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.002 0.0243
Schistosoma mansoni tubulin subunit alpha 0.0207 0.0532 0.0532
Schistosoma mansoni hypothetical protein 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0305 0.0802 1
Brugia malayi ORL1-like opioid receptor 0.002 0.0021 0.0097
Onchocerca volvulus 0.0037 0.0067 0.082
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Brugia malayi Tubulin beta-1 chain 0.0258 0.0674 0.3209
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Plasmodium vivax tubulin alpha chain, putative 0.0207 0.0532 0.6635
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0077 0.1143
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.001 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0085 0.0183
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Leishmania major cathepsin L-like protease 0.0083 0.0192 0.2391
Loa Loa (eye worm) hypothetical protein 0.0131 0.0326 0.0326
Echinococcus granulosus fmrfamide receptor 0.002 0.0021 0.0097
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0072 0.0078
Brugia malayi Carboxylesterase family protein 0.0778 0.2098 1
Echinococcus multilocularis lamin dm0 0.003 0.0049 0.0104
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0106 0.0256 0.0256
Brugia malayi Tubulin beta chain 0.0063 0.0138 0.0654
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.002
Giardia lamblia PHD finger protein 15 0.0028 0.0044 0.0533
Schistosoma mansoni fad oxidoreductase 0.0305 0.0802 0.0801
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.007 0.0159 0.0344
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0305 0.0802 0.1746
Trypanosoma brucei epsilon tubulin 0.0145 0.0362 0.4517
Trichomonas vaginalis tubulin epsilon chain, putative 0.0207 0.0532 0.7902
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0021 0.0255
Trypanosoma cruzi beta tubulin, putative 0.0258 0.0674 0.8399
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trichomonas vaginalis diaminopimelate decarboxylase, putative 0.0202 0.052 0.7719
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0071 0.0877
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.011 0.1357
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.005 0.0106
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0017 0.0202
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072
Trichomonas vaginalis esterase, putative 0.0039 0.0072 0.1075
Entamoeba histolytica hypothetical protein 0.0043 0.0085 0.1048
Giardia lamblia Alpha-tubulin 0.0207 0.0532 0.6635
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0021 0.0045
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0006 0.0023
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0067 0.082
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0021 0.0045
Echinococcus granulosus orexin receptor type 2 0.002 0.0021 0.0097
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0326 0.0325
Loa Loa (eye worm) hypothetical protein 0.0143 0.0358 0.0358
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Onchocerca volvulus 0.002 0.0021 0.0255
Mycobacterium ulcerans hypothetical protein 0.0023 0.003 0.0029
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0021 0.002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0001 0.0012
Echinococcus granulosus tubulin beta 1 chain 0.0258 0.0674 0.3209
Loa Loa (eye worm) carboxylesterase 0.0131 0.0326 0.0326
Brugia malayi cDNA sequence BC016226 0.0305 0.0802 0.3821
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Echinococcus granulosus Tubulin beta 2C chain 0.0258 0.0674 0.3209
Schistosoma mansoni nuclear receptor 0.0014 0.0005 0.0004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0018 0.0017
Onchocerca volvulus 0.0015 0.0007 0.0075
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0021 0.0045
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0015 0.0007 0.0085
Brugia malayi mbt repeat family protein 0.0105 0.0253 0.1202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Onchocerca volvulus 0.002 0.0021 0.0255
Schistosoma mansoni tubulin subunit beta 0.0258 0.0674 0.0673
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0159 0.0158
Brugia malayi Melibiase family protein 0.0073 0.0166 0.0788
Onchocerca volvulus 0.002 0.002 0.0236
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0033
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0063 0.0138 0.1719
Brugia malayi Serotonin receptor 0.002 0.0021 0.0097
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0325 0.0325
Onchocerca volvulus 0.002 0.0021 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Plasmodium vivax vivapain-2 0.0037 0.0067 0.082
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0305 0.0802 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.005 0.0232
Echinococcus multilocularis Tubulin beta 2C chain 0.0258 0.0674 0.1467
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0049 0.0049
Brugia malayi Cathepsin L-like precursor 0.0037 0.0067 0.0313
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.002 0.0243
Mycobacterium leprae Possible oxidoreductase 0.0015 0.0007 0.0006
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0988
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0079 0.0078
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0021 0.0022 0.0269
Giardia lamblia Aldose reductase 0.0052 0.0108 0.1333
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0052 0.0108 0.0233
Entamoeba histolytica cysteine proteinase 2 0.0019 0.0018 0.021
Onchocerca volvulus 0.0045 0.0089 0.1095
Loa Loa (eye worm) hypothetical protein 0.0031 0.005 0.005
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0021 0.0097
Loa Loa (eye worm) tubulin beta chain 0.0258 0.0674 0.0674
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0067 0.0143
Trypanosoma brucei beta tubulin 0.0258 0.0674 0.84
Toxoplasma gondii exonuclease III APE 0.0038 0.0071 0.0887
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.0305 0.0802 0.0801
Trichomonas vaginalis pyridoxal-dependent decarboxylase, putative 0.0202 0.052 0.7719
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0017 0.0259
Echinococcus multilocularis g protein coupled receptor 0.002 0.0021 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Brugia malayi conserved hypotetical protein 0.0014 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Schistosoma mansoni ap endonuclease 0.0038 0.0071 0.007
Mycobacterium tuberculosis Carboxylesterase LipT 0.0131 0.0326 0.0355
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0133 0.033 0.0717
Loa Loa (eye worm) hypothetical protein 0.0305 0.0802 0.0802
Echinococcus granulosus g protein coupled receptor 0.002 0.0021 0.0097
Toxoplasma gondii beta-1 tubulin, putative 0.0258 0.0674 0.84
Leishmania major beta tubulin 0.0258 0.0674 0.8399
Trypanosoma cruzi tubulin delta chain 0.0063 0.0138 0.1711
Trypanosoma cruzi zeta tubulin, putative 0.0063 0.0138 0.1711
Brugia malayi hypothetical protein 0.0021 0.0023 0.0108
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0001 0.001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.005 0.0106
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus multilocularis beta tubulin 0.0258 0.0674 0.1467
Entamoeba histolytica cysteine protease, putative 0.0019 0.0018 0.021
Schistosoma mansoni pyruvate kinase 0.0036 0.0066 0.0065
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0005 0.0021
Brugia malayi jmjC domain containing protein 0.0093 0.0221 0.1049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.005 0.0232
Loa Loa (eye worm) MBCTL1 0.0119 0.0293 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Echinococcus multilocularis pyruvate kinase 0.0019 0.0017 0.0035
Loa Loa (eye worm) BEN-1 protein 0.0258 0.0674 0.0674
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0033
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0305 0.0802 0.0801
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.003 0.0029
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0041 0.0508
Schistosoma mansoni tubulin subunit alpha 0.0063 0.0138 0.0137
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.0293 0.0636
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0089 0.0088
Echinococcus granulosus tubulin subunit TubB 0.0207 0.0532 0.2535
Schistosoma mansoni pol-related 0.0052 0.0108 0.0107
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.0293 0.1391
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Entamoeba histolytica tubulin gamma chain 0.0145 0.0362 0.4511
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0072 0.0341
Onchocerca volvulus 0.0039 0.0072 0.0893
Echinococcus multilocularis tubulin epsilon chain 0.0145 0.0362 0.0788
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0067 0.0987
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0066 0.0819
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0023 0.0108
Echinococcus granulosus g-protein coupled receptor 0.002 0.0021 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0067 0.0987
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus granulosus tubulin subunit beta 0.0258 0.0674 0.3209
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.0305 0.0802 0.0874
Echinococcus granulosus carboxylesterase 5A 0.0778 0.2098 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0041 0.019
Brugia malayi Muscleblind-like protein 0.0155 0.0392 0.1864
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni lipoxygenase 0.0059 0.0128 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.018 0.2666
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0021 0.0022 0.0022
Brugia malayi PHD-finger family protein 0.0015 0.0007 0.0032
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.002 0.0093
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0021 0.0045
Trypanosoma brucei tubulin delta chain 0.0063 0.0138 0.1719
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0052 0.0108 0.051
Onchocerca volvulus Alhambra homolog 0.0028 0.0044 0.0533
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0071 0.007
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0021 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.0052 0.0108 0.0117
Entamoeba histolytica hypothetical protein 0.0043 0.0085 0.1048
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0013 0.0001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0067 0.0987
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0014 0.0014
Onchocerca volvulus 0.003 0.0049 0.0595
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0085 0.1269
Schistosoma mansoni coup transcription factor 0.0031 0.005 0.0049
Trichomonas vaginalis tubulin alpha chain, putative 0.0145 0.0362 0.5377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0033 0.0493
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Echinococcus granulosus cathepsin l1 0.0025 0.0033 0.0154
Leishmania major alpha tubulin 0.0207 0.0532 0.6635
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0192 0.2399
Giardia lamblia Gamma tubulin 0.0145 0.0362 0.4511
Loa Loa (eye worm) oxidoreductase 0.0013 0.0001 0.0001
Giardia lamblia Beta tubulin 0.0258 0.0674 0.8399
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.001 0.0044
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0044 0.0043
Brugia malayi hypothetical protein 0.002 0.0021 0.0097
Trichomonas vaginalis tubulin gamma chain, putative 0.0145 0.0362 0.5377
Echinococcus granulosus cathepsin L 0.0019 0.0018 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.003 0.0029
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0159 0.0158
Schistosoma mansoni ABC transporter 0.0018 0.0014 0.0013
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0071 0.5129
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0021 0.002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0079 0.0182 0.0864
Brugia malayi hypothetical protein 0.0014 0.0005 0.0021
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0108
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.002 0.0253
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0072 0.0164 0.0163
Plasmodium falciparum pyruvate kinase 0.0036 0.0066 0.081
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.002 0.0243
Toxoplasma gondii carbonyl reductase 1, putative 0.0013 0.0001 0.001
Echinococcus granulosus tubulin alpha chain 0.0207 0.0532 0.2535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0021 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0044 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.002 0.0301
Entamoeba histolytica cysteine protease, putative 0.0037 0.0067 0.082
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.002 0.0243
Trichomonas vaginalis aldo-keto reductase, putative 0.0052 0.0108 0.1598
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0082 0.019 0.2821
Echinococcus granulosus muscleblind protein 0.0155 0.0392 0.1864
Echinococcus granulosus tubulin alpha 1C chain 0.0207 0.0532 0.2535
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.005 0.0608
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0164 0.2439
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0067 0.0067
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0076 0.0076
Loa Loa (eye worm) PHD-finger family protein 0.0045 0.009 0.009
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0067 0.082
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0305 0.0802 0.3821
Loa Loa (eye worm) beta-tubulin 0.0258 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0326 0.0325
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0009 0.0127
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0018 0.021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0072

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 9.48 nM Inhibitory activity of the compound against Acetylcholinesterase ChEMBL. 8893840
Ki (binding) = 17.5 nM Inhibitory activity of the compound was calculated for the model Acetylcholinesterase (Expt-1) ChEMBL. 8893840
Ki (binding) = 37.6 nM Inhibitory activity of the compound was calculated for the model Acetylcholinesterase (Expt-2) ChEMBL. 8893840

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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