Detailed information for compound 1699331

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1032.22 | Formula: C49H69N13O10S
  • H donors: 11 H acceptors: 11 LogP: -1.05 Rotable bonds: 32
    Rule of 5 violations (Lipinski): 4
  • SMILES: CNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CSC([C@@H]1C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)O)Cc1ccccc1)Cc1nc[nH]c1)(C)C)Cc1ccc(cc1)O)C(C)C)CCCN=C(N)N
  • InChi: 1S/C49H69N13O10S/c1-28(2)39(60-41(65)33(56-38(64)25-52-5)13-9-19-54-48(50)51)43(67)57-34(21-30-15-17-32(63)18-16-30)46(70)62-27-73-49(3,4)40(62)44(68)58-35(23-31-24-53-26-55-31)45(69)61-20-10-14-37(61)42(66)59-36(47(71)72)22-29-11-7-6-8-12-29/h6-8,11-12,15-18,24,26,28,33-37,39-40,52,63H,9-10,13-14,19-23,25,27H2,1-5H3,(H,53,55)(H,56,64)(H,57,67)(H,58,68)(H,59,66)(H,60,65)(H,71,72)(H4,50,51,54)/t33-,34-,35-,36+,37-,39-,40-/m0/s1
  • InChiKey: ULXJCGPTFXHIPX-BAYAHZKWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Angiotensin II receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis thyrotropin releasing hormone receptor Angiotensin II receptor   359 aa 334 aa 23.7 %
Echinococcus multilocularis allatostatin A receptor Angiotensin II receptor   359 aa 348 aa 25.9 %
Brugia malayi putative neuropeptide receptor NPR1 Angiotensin II receptor   359 aa 295 aa 27.5 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Angiotensin II receptor   359 aa 311 aa 23.5 %
Echinococcus granulosus allatostatin A receptor Angiotensin II receptor   359 aa 348 aa 25.9 %
Loa Loa (eye worm) neuropeptide F receptor Angiotensin II receptor   359 aa 356 aa 24.2 %
Onchocerca volvulus Angiotensin II receptor   359 aa 294 aa 23.8 %
Onchocerca volvulus Angiotensin II receptor   359 aa 395 aa 23.0 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Angiotensin II receptor   359 aa 406 aa 20.0 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor   359 aa 335 aa 23.3 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Angiotensin II receptor   359 aa 352 aa 20.5 %
Echinococcus granulosus neuropeptide receptor Angiotensin II receptor   359 aa 316 aa 25.0 %
Echinococcus multilocularis neuropeptide receptor Angiotensin II receptor   359 aa 316 aa 25.3 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Angiotensin II receptor   359 aa 407 aa 19.4 %
Echinococcus multilocularis growth hormone secretagogue receptor type 1 Angiotensin II receptor   359 aa 351 aa 21.9 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Angiotensin II receptor   359 aa 346 aa 18.2 %
Brugia malayi ORL1-like opioid receptor Angiotensin II receptor   359 aa 314 aa 20.1 %
Onchocerca volvulus Angiotensin II receptor   359 aa 303 aa 25.1 %
Schistosoma japonicum Rhodopsin, putative Angiotensin II receptor   359 aa 327 aa 24.2 %
Echinococcus granulosus tm gpcr rhodopsin Angiotensin II receptor   359 aa 303 aa 22.4 %
Onchocerca volvulus Angiotensin II receptor   359 aa 312 aa 19.2 %
Echinococcus granulosus thyrotropin releasing hormone receptor Angiotensin II receptor   359 aa 337 aa 24.0 %
Echinococcus granulosus growth hormone secretagogue receptor type 1 Angiotensin II receptor   359 aa 351 aa 21.9 %
Brugia malayi GnHR receptor homolog Angiotensin II receptor   359 aa 364 aa 20.9 %
Schistosoma mansoni opsin-like receptor Angiotensin II receptor   359 aa 299 aa 25.1 %
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Angiotensin II receptor   359 aa 303 aa 22.4 %
Onchocerca volvulus Angiotensin II receptor   359 aa 314 aa 25.8 %
Onchocerca volvulus Angiotensin II receptor   359 aa 386 aa 24.9 %
Schistosoma mansoni adenoreceptor Angiotensin II receptor   359 aa 329 aa 24.0 %
Echinococcus multilocularis G-protein coupled receptor, putative Angiotensin II receptor   359 aa 308 aa 22.4 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Angiotensin II receptor   359 aa 336 aa 22.3 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor   359 aa 330 aa 26.7 %
Schistosoma mansoni peptide (allatostatin)-like receptor Angiotensin II receptor   359 aa 314 aa 26.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0026 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0043 0.0034 0.0033
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0564 0.0663 0.0663
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0034 0.0031
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0125 0.0133 0.0132
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0146 0.0145
Entamoeba histolytica PH domain containing protein kinase, putative 0.0091 0.0092 0.0092
Brugia malayi Cytochrome P450 family protein 0.0023 0.001 0.001
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0039 0.0029 0.0029
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0083 0.0082 0.1204
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0026 0.0013 0.0013
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0028 0.0424
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0036 0.0026 0.0025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0016 0.0001 0.0001
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0017 0.0003 0.0003
Brugia malayi Protein kinase c protein 2 0.0018 0.0004 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0029 0.0389
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) RNA binding protein 0.0128 0.0137 0.0136
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0137 0.0136
Schistosoma mansoni Mername-AA248 (C02 family) 0.0017 0.0003 0.0003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0844 0.1001 0.1001
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0017 0.0003 0.0003
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0017 0.0003 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0146 0.0146
Schistosoma mansoni biogenic amine receptor 0.0135 0.0146 0.0146
Echinococcus granulosus peptide allatostatin:somatostatin 0.0135 0.0146 0.0146
Echinococcus granulosus NEDD4 E3 ubiquitin protein ligase WWP1 0.0017 0.0003 0.0003
Schistosoma mansoni cell adhesion molecule 0.0022 0.0008 0.0008
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0008 0.0008
Brugia malayi CXXC zinc finger family protein 0.0059 0.0054 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.4501 0.5414 0.5413
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.017 0.0187 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.4494 0.5406 0.5404
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0034 0.0034
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Entamoeba histolytica protein kinase rad3, putative 0.1588 0.1898 0.1898
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0014 0.0014
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0026 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.2821 0.3387 0.3385
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0017 0.0003 0.0003
Trypanosoma brucei rac serine-threonine kinase, putative 0.0133 0.0143 0.014
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0028 0.0025
Schistosoma mansoni E3 ubiquitin-protein ligase nedd-4 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Conserved protein 0.0038 0.0028 0.0424
Brugia malayi Tachykinin-like peptides receptor 99D 0.0135 0.0146 0.0145
Brugia malayi phospholipase C homolog 0.0017 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0026 0.0013 0.0013
Echinococcus granulosus lamin dm0 0.0017 0.0003 0.0003
Echinococcus granulosus lysosomal alpha glucosidase 0.0336 0.0387 0.0387
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0056 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Echinococcus granulosus Immunoglobulin 0.0037 0.0027 0.0027
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.0047
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0026 0.0013 0.0195
Echinococcus multilocularis Glutaredoxin protein 5 0.0083 0.0082 0.0082
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0039 0.0029 0.0029
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0081 0.008 0.1161
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) BEN-1 protein 0.0024 0.0012 0.0011
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.1223 0.1458 0.1458
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0545 0.064 0.064
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Brugia malayi glutathione reductase 0.0038 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni glut4 vesicle protein-related 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Giardia lamblia Hypothetical protein 0.0023 0.001 0.0002
Brugia malayi Dopamine receptor protein 2 0.0135 0.0146 0.0145
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0146 0.0146
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0017 0.0003 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0016 0.0001 0.0001
Echinococcus granulosus unc 13 munc13 0.0017 0.0003 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0135 0.0146 0.0146
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Onchocerca volvulus Bile acid receptor homolog 0.0016 0.0001 0.0008
Giardia lamblia GTOR 0.8301 1 1
Schistosoma mansoni hypothetical protein 0.0075 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0135 0.0146 0.0146
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0023 0.001 0.001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0729 0.0862 0.0859
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0018 0.0004 0.0001
Echinococcus granulosus Glutaredoxin protein 5 0.0083 0.0082 0.0082
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.001 0.0007
Schistosoma mansoni hypothetical protein 0.028 0.0321 0.0321
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0824 0.0977 0.0977
Echinococcus granulosus g protein coupled receptor 0.0135 0.0146 0.0146
Plasmodium falciparum pyruvate kinase 0.0023 0.0009 0.0098
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0039 0.0029 0.0029
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0137 0.0136
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0146 0.0146
Schistosoma mansoni growth hormone secretagogue receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0016 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.4961 0.5969 0.5968
Schistosoma mansoni alpha glucosidase 0.0074 0.0072 0.0072
Leishmania major cytochrome p450-like protein 0.0023 0.001 0.001
Echinococcus multilocularis geminin 0.028 0.0321 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0088 0.0085
Schistosoma mansoni microtubule-associated protein tau 0.0701 0.0829 0.0829
Schistosoma mansoni neuropeptide f receptor 76f 0.0135 0.0146 0.0146
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0081 0.008 0.0079
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0004 0.0004
Brugia malayi Prion-like- 0.0022 0.0008 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis G-protein coupled receptor, putative 0.0135 0.0146 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0137 0.0137
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0026 0.0013 0.001
Echinococcus granulosus glycogen phosphorylase 0.0212 0.0238 0.0238
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0028 0.0424
Schistosoma mansoni nephrin 0.0046 0.0038 0.0038
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0564 0.0663 0.0663
Trypanosoma brucei Flagellar Member 6 0.0026 0.0013 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0016 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis musashi 0.0017 0.0003 0.0003
Schistosoma mansoni lamin 0.0017 0.0003 0.0003
Treponema pallidum cyclic nucleotide binding protein 0.0026 0.0013 0.017
Echinococcus granulosus UNCoordinated family member unc 13 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0545 0.064 0.0638
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0135 0.0146 0.0145
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Echinococcus multilocularis extended synaptotagmin 2 0.0017 0.0003 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0029 0.044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0016 0.0001 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.0545 0.064 0.064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0016 0.0013
Schistosoma mansoni glycogen phosphorylase 0.0212 0.0238 0.0238
Echinococcus granulosus hemicentin 1 0.0022 0.0008 0.0008
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0043 0.0034 0.0034
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0022 0.0009 0.0009
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0603 0.071 0.0707
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.01 0.1553
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0026 0.0026
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0081 0.008 0.008
Echinococcus multilocularis hyperpolarization activated cyclic 0.0039 0.0029 0.0029
Brugia malayi RNA, U transporter 1 0.0083 0.0083 0.0082
Mycobacterium ulcerans hypothetical protein 0.0026 0.0013 0.0425
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0047 0.0038 0.0038
Schistosoma mansoni neuropeptide receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0037 0.0027 0.0027
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0026 0.0013 0.0013
Leishmania major protein kinase A regulatory subunit, putative 0.0026 0.0013 0.0013
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0023 0.001 0.001
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.0146 0.0146
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.0638
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0027 0.0014 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Echinococcus multilocularis peroxidasin 0.0022 0.0008 0.0008
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0135 0.0146 0.0145
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0545 0.064 0.064
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0126 0.0134 0.0134
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.017 0.0187 0.0179
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.0115 0.0114
Echinococcus granulosus alpha 1A adrenergic receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0013
Trichomonas vaginalis tubulin epsilon chain, putative 0.0024 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Mycobacterium tuberculosis Probable dehydrogenase 0.0088 0.0088 0.1369
Schistosoma mansoni hypothetical protein 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Toxoplasma gondii AGC kinase 0.0125 0.0133 0.0175
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0016 0.0013
Echinococcus granulosus neuropeptide receptor 0.0135 0.0146 0.0146
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.8301 1 1
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0026 0.0013 0.0013
Echinococcus multilocularis NEDD4 E3 ubiquitin protein ligase WWP1 0.0017 0.0003 0.0003
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0008 0.0117
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0072 0.0072
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0028 0.0028
Entamoeba histolytica Rap/Ran GTPase activating protein, putative 0.0017 0.0003 0.0002
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0662 0.0781 0.0781
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0135 0.0146 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0073 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Echinococcus granulosus ecdysone induced protein 78C 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0017 0.0003 0.0003
Brugia malayi N-terminal motif family protein 0.0026 0.0013 0.0013
Echinococcus granulosus Glycosyl transferase family 35 0.0212 0.0238 0.0238
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.3459 0.4156 0.4154
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0146 0.0145
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0072 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0135 0.0146 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.2811 0.3374 0.3372
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus extended synaptotagmin 2 0.0017 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0027 0.0026
Trichomonas vaginalis esterase, putative 0.0038 0.0028 0.0025
Echinococcus granulosus contactin 0.0022 0.0008 0.0008
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0047 0.0038 0.0038
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.0008 0.0008
Schistosoma mansoni tyrosine kinase 0.0025 0.0012 0.0012
Brugia malayi Synapse defective protein 1 0.0017 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0035 0.0024 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0146 0.0146
Loa Loa (eye worm) phosphatidylinositol kinase 0.0545 0.064 0.064
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0135 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Entamoeba histolytica glycogenphosphorylase, putative 0.0092 0.0093 0.0092
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Trypanosoma brucei cAMP binding protein, putative 0.0043 0.0034 0.0031
Mycobacterium leprae conserved hypothetical protein 0.0545 0.064 1
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0026 0.0013 0.0013
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Leishmania major GTP-binding protein, putative 0.0022 0.0008 0.0008
Schistosoma mansoni immunophilin 0.017 0.0187 0.0187
Schistosoma mansoni amine GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) tubulin beta-1 chain 0.0024 0.0012 0.0011
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0564 0.0663 0.0663
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.017 0.0187 0.0186
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0043 0.0034 0.0034
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0029 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.8301 1 1
Echinococcus multilocularis neural cell expressed, developmentally 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus glycogen phosphorylase 0.0212 0.0238 0.0238
Echinococcus granulosus copine 9 0.0017 0.0003 0.0003
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0026 0.0013 0.0005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0135 0.0146 0.0145
Schistosoma mansoni ran 0.0022 0.0008 0.0008
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0167 0.0183 0.0183
Echinococcus multilocularis allatostatin A receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Schistosoma mansoni neuropeptide receptor 0.0135 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0545 0.064 0.064
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Trypanosoma cruzi beta tubulin, putative 0.0024 0.0012 0.0009
Echinococcus multilocularis lachesin 0.0022 0.0008 0.0008
Echinococcus granulosus roundabout 2 0.0059 0.0053 0.0053
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus granulosus neural cell expressed developmentally 0.0017 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0072 0.0069
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0037 0.0027 0.0032
Echinococcus granulosus serine/threonine protein kinase 0.0091 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Echinococcus multilocularis GPCR, family 2 0.0035 0.0024 0.0024
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0017 0.0003 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0016 0.0015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2859 0.3433 0.3431
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0072 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0617 0.0727 0.0727
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0005
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0026 0.0013 0.0013
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0028 0.0424
Brugia malayi neuropeptide F receptor 0.0135 0.0146 0.0145
Echinococcus multilocularis serine:threonine protein kinase N2 0.0043 0.0034 0.0034
Mycobacterium ulcerans pyruvate kinase 0.0023 0.0009 0.0294
Onchocerca volvulus 0.0135 0.0146 0.2203
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.4494 0.5406 0.5404
Plasmodium vivax ataxin-2 like protein, putative 0.0034 0.0023 0.03
Schistosoma mansoni opsin-like receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0024 0.0024
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0026 0.0026
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0026 0.0013 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0018 0.0015
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0026 0.0013 0.0201
Entamoeba histolytica Ran family GTPase 0.0022 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.1042 0.124 0.1238
Brugia malayi GnHR receptor homolog 0.0135 0.0146 0.0145
Echinococcus multilocularis somatostatin receptor 0.0135 0.0146 0.0146
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0091 0.0092 0.0089
Onchocerca volvulus 0.0017 0.0003 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0026 0.0026
Echinococcus granulosus cGMP dependent protein kinase 0.0027 0.0014 0.0014
Echinococcus multilocularis snurportin 1 0.0313 0.036 0.036
Echinococcus granulosus otoferlin 0.0017 0.0003 0.0003
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0038 0.0048
Echinococcus granulosus FTZ F1 alpha 0.0016 0.0001 0.0001
Entamoeba histolytica calcium-binding protein, putative 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.1768 0.2116 0.2116
Giardia lamblia Kinase, AGC PKA 0.0083 0.0082 0.0074
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus high affinity choline transporter 1 0.0235 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus lamin 0.0017 0.0003 0.0003
Echinococcus granulosus GPCR family 2 0.0035 0.0024 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0028 0.0894
Leishmania major trypanothione reductase 0.0038 0.0029 0.0028
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0564 0.0663 0.0663
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0009 0.0135
Schistosoma mansoni neuropeptide receptor 0.0135 0.0146 0.0146
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0043 0.0034 0.0034
Schistosoma mansoni septate junction protein 0.0022 0.0008 0.0008
Brugia malayi beta-lactamase family protein 0.0038 0.0028 0.0027
Echinococcus multilocularis beta tubulin 0.0024 0.0012 0.0012
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.017 0.0187 0.0184
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0009
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0028 0.0424
Entamoeba histolytica hypothetical protein 0.0024 0.0011 0.001
Echinococcus multilocularis protein kinase c iota type 0.0043 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0007
Schistosoma mansoni glutaminase 0.0266 0.0304 0.0304
Loa Loa (eye worm) phosphatidylinositol 3 0.8301 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0001 0.0001
Entamoeba histolytica tubulin family protein 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0072 0.0069
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0028 0.0027
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0004 0.0003
Brugia malayi steroid hormone receptor 0.0016 0.0001 0.0001
Echinococcus granulosus sodium:glucose cotransporter 0.0026 0.0013 0.0013
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.001 0.001
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0545 0.064 0.0638
Trichomonas vaginalis bromodomain-containing protein, putative 0.0037 0.0027 0.0024
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Onchocerca volvulus Putative cc2d1b protein 0.0017 0.0003 0.0037
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Trypanosoma cruzi cAMP binding protein, putative 0.0043 0.0034 0.0031
Schistosoma mansoni hypothetical protein 0.0135 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.4961 0.5969 0.5968
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1042 0.124 0.1238
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus Tubulin beta 2C chain 0.0024 0.0012 0.0012
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0023 0.001 0.001
Echinococcus granulosus snurportin 1 0.0313 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0013
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.062 0.0731 0.0731
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0135 0.0146 0.0146
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0336 0.0387 0.0387
Onchocerca volvulus 0.0017 0.0003 0.0038
Mycobacterium ulcerans regulatory protein 0.0026 0.0013 0.0425
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0729 0.0862 0.0861
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0081 0.008 0.0079
Brugia malayi G-protein coupled receptor 0.0135 0.0146 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0016 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0146 0.0146
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0016 0.0013
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.7078 0.8524 0.8524
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0584 0.0687 0.0679
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0603 0.071 0.0709
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Loa Loa (eye worm) glutathione reductase 0.0038 0.0029 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.6611 0.796 0.796
Entamoeba histolytica hypothetical protein 0.0545 0.064 0.064
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0016 0.0015
Schistosoma mansoni synaptotagmin 12 0.0017 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0018 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.4501 0.5414 0.5413
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1588 0.1898 0.1896
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0729 0.0862 0.0859
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) phosphatidylinositol 3 0.0857 0.1016 0.1016
Loa Loa (eye worm) hypothetical protein 0.1683 0.2014 0.2013
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0137 0.0137
Schistosoma mansoni protein kinase C 0.0017 0.0003 0.0003
Mycobacterium leprae Conserved hypothetical protein 0.0026 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0183 0.0203 0.02
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Entamoeba histolytica protein kinase, putative 0.0043 0.0034 0.0033
Echinococcus multilocularis tubulin beta 1 chain 0.0024 0.0012 0.0012
Leishmania major peptidylprolyl isomerase-like protein 0.017 0.0187 0.0186
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.017 0.0187 0.0186
Brugia malayi carbohydrate phosphorylase 0.0212 0.0238 0.0238
Schistosoma mansoni serine/threonine-protein kinase 0.0091 0.0092 0.0092
Onchocerca volvulus 0.0017 0.0003 0.0037
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Entamoeba histolytica protein kinase, putative 0.0133 0.0143 0.0142
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0092 0.0093 0.1445
Loa Loa (eye worm) FKBP5 protein 0.017 0.0187 0.0186
Schistosoma mansoni adenoreceptor 0.0135 0.0146 0.0146
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.1223 0.1458 0.1458
Schistosoma mansoni amine GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.0008 0.0008
Echinococcus granulosus hypothetical protein 0.0135 0.0146 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0055 0.0055
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0028 0.0424
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis nervana 2 0.0082 0.0081 0.0081
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.001 0.001
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0009 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0057 0.0051 0.0051
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0564 0.0663 0.0661
Loa Loa (eye worm) hypothetical protein 0.0059 0.0053 0.0052
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.0113
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0088 0.0088 0.1369
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Brugia malayi Copine family protein 0.0017 0.0003 0.0002
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0603 0.071 0.0709
Brugia malayi Cytochrome P450 family protein 0.0023 0.001 0.001
Echinococcus multilocularis serine protein kinase ATM 0.1588 0.1898 0.1898
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.001 0.001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.069 0.0815 0.0815
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0679 0.0802 0.0802
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Mycobacterium ulcerans glutaminase 0.0266 0.0304 1
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0004 0.0004
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0016 0.0001 0.0001
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0009 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0026 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0137 0.0137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0545 0.064 0.064
Echinococcus multilocularis serine:threonine protein kinase N2 0.0043 0.0034 0.0034
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0023 0.001 0.0154
Leishmania major phosphatidylinositol kinase related protein, putative 0.0545 0.064 0.064
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.017 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0008 0.0008
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0146 0.0159 0.0159
Echinococcus granulosus Immunoglobulin E set 0.0017 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0034 0.0034
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.8301 1 1
Echinococcus granulosus voltage gated potassium channel 0.0057 0.0051 0.0051
Schistosoma mansoni ran 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.001
Plasmodium vivax tubulin beta chain, putative 0.0024 0.0012 0.0132
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0146 0.0146
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0793 0.0939 0.0939
Trichomonas vaginalis tubulin, putative 0.0024 0.0012 0.0009
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.0638
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0016 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.1598 0.1911 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.1768 0.2116 0.2114
Echinococcus multilocularis synaptotagmin 0.0017 0.0003 0.0003
Echinococcus multilocularis fk506 binding protein 0.017 0.0187 0.0187
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0043 0.0034 0.0033
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0545 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.5569 0.6702 0.6701
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0029 0.0026
Echinococcus granulosus synaptotagmin 0.0017 0.0003 0.0003
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Leishmania major pyruvate kinase 0.0023 0.0009 0.0009
Echinococcus granulosus tubulin beta 1 chain 0.0024 0.0012 0.0012
Schistosoma mansoni synaptotagmin 12 0.0017 0.0003 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0034 0.0023 0.03
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0135 0.0146 0.0146
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0016 0.0013
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Schistosoma mansoni lamin 0.0017 0.0003 0.0003
Echinococcus granulosus synaptotagmin 0.0017 0.0003 0.0003
Toxoplasma gondii target of rapamycin (TOR), putative 0.6185 0.7446 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0564 0.0663 0.0661
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0545 0.064 0.0638
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Mycobacterium leprae Possible transporter protein 0.0018 0.0004 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0057 0.0051 0.0051
Brugia malayi TAR-binding protein 0.0128 0.0137 0.0136
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0146 0.0145
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1768 0.2116 0.284
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0034 0.0034
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0072 0.0072
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0049 0.0041 0.0041
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0026 0.0013 0.0013
Schistosoma mansoni synaptic ras gtpase activating protein syngap 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0063 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0016 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0001 0.0001
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0028 0.0027
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0146 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0662 0.0781 0.0781
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0029 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0072 0.0069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0146 0.0146
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0081
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0026 0.0013 0.0013
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0135 0.0146 0.0146
Brugia malayi Melatonin receptor type 1A 0.0135 0.0146 0.0145
Echinococcus multilocularis Tubulin beta 2C chain 0.0024 0.0012 0.0012
Echinococcus multilocularis Glycosyl transferase, family 35 0.0212 0.0238 0.0238
Echinococcus granulosus roundabout 2 0.0022 0.0008 0.0008
Echinococcus granulosus g protein coupled receptor 0.0135 0.0146 0.0146
Onchocerca volvulus 0.0017 0.0003 0.0037
Trichomonas vaginalis fk506-binding protein, putative 0.0023 0.001 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0014 0.0014
Brugia malayi Synaptotagmin I 0.0017 0.0003 0.0002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0122 0.013 0.013
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.069 0.0815 0.0815
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2859 0.3433 0.3433
Entamoeba histolytica hypothetical protein, conserved 0.0017 0.0003 0.0002
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Leishmania major eukaryotic translation initiation factor-like protein 0.0056 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.2811 0.3374 0.3372
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0146 0.0145
Entamoeba histolytica C2 domain protein, putative 0.0017 0.0003 0.0002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0135 0.0146 0.2203
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0039 0.0029 0.0029
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Loa Loa (eye worm) glycogen phosphorylase 0.0212 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Echinococcus multilocularis myoferlin 0.0017 0.0003 0.0003
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0018 0.0004 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0072 0.0069
Loa Loa (eye worm) hypothetical protein 0.1588 0.1898 0.1898
Schistosoma mansoni rho gtpase activating protein 0.0017 0.0003 0.0003
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0039 0.0029 0.0029
Brugia malayi Serotonin receptor 0.0135 0.0146 0.0145
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0083 0.0082 0.008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0146 0.0146
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0017 0.0003 0.0003
Toxoplasma gondii beta-1 tubulin, putative 0.0024 0.0012 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0001 0.0001
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Echinococcus multilocularis 0.0023 0.001 0.001
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0018 0.0004 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0184 0.0204 0.0203
Treponema pallidum catabolite gene activator 0.0026 0.0013 0.017
Schistosoma mansoni hypothetical protein 0.0081 0.008 0.008
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis synaptotagmin 0.0017 0.0003 0.0003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0024 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0195 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0014 0.0014
Loa Loa (eye worm) acetyltransferase 0.0126 0.0134 0.0134
Trypanosoma cruzi protein kinase A regulatory subunit 0.0026 0.0013 0.001
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0028 0.0424
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0026 0.0013 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.4501 0.5414 0.5413
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni titin 0.0022 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Echinococcus multilocularis glycogen phosphorylase 0.0212 0.0238 0.0238
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0035 0.0024 0.0024
Echinococcus granulosus myoferlin 0.0017 0.0003 0.0003
Brugia malayi Dopamine receptor protein 1 0.0135 0.0146 0.0145
Leishmania major hypothetical protein, conserved 0.0633 0.0746 0.0746
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0564 0.0663 0.0661
Mycobacterium tuberculosis Conserved protein 0.0026 0.0013 0.0201
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0008 0.0008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1588 0.1898 0.1898
Schistosoma mansoni inositol transporter 0.0026 0.0013 0.0013
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2811 0.3374 0.3372
Onchocerca volvulus 0.0026 0.0013 0.0195
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0135 0.0146 0.0145
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0195 0.0218 0.0218
Echinococcus multilocularis Zinc finger, PHD finger 0.0564 0.0663 0.0663
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0038 0.0028 0.0424
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Schistosoma mansoni coup transcription factor 0.0016 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0023 0.001 0.001
Echinococcus granulosus twitchin 0.0047 0.0039 0.0039
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0008 0.0008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0039 0.0029 0.0029
Brugia malayi Pyruvate kinase, muscle isozyme 0.0023 0.0009 0.0009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0146 0.0146
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0026 0.0013 0.0013
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0043 0.0034 0.0034
Onchocerca volvulus 0.0017 0.0003 0.0038
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0004 0.0004
Brugia malayi translation initiation factor 4E 0.0056 0.005 0.005
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.0047
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0013 0.0014
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0008
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0195 0.0218 0.0218
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0039 0.0029 0.0029
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0026 0.0013 0.0013
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0047 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0082 0.0081 0.0081
Leishmania major importin beta-1 subunit, putative 0.0024 0.0011 0.001
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.8301 1 1
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0023 0.001 0.0007
Onchocerca volvulus 0.0135 0.0146 0.2203
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0004 0.0001
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0564 0.0663 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0115 0.0114
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0545 0.064 0.9652
Schistosoma mansoni alpha-glucosidase 0.0289 0.0331 0.0331
Echinococcus granulosus roundabout 2 0.0022 0.0008 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0146 0.0146
Trichomonas vaginalis immunophilin, putative 0.017 0.0187 0.0184
Loa Loa (eye worm) AGC/PKN protein kinase 0.0043 0.0034 0.0033
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.017 0.0187 0.0186
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.017 0.0187 0.0187
Echinococcus multilocularis pyruvate kinase 0.0018 0.0004 0.0004
Echinococcus granulosus synaptotagmin protein 4 0.0017 0.0003 0.0003
Loa Loa (eye worm) glutaminase 2 0.0266 0.0304 0.0303
Schistosoma mansoni sodium/solute symporter 0.0026 0.0013 0.0013
Trichomonas vaginalis tubulin gamma chain, putative 0.0024 0.0012 0.0009
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0018 0.0018
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0016 0.0013
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0016 0.0001 0.0001
Mycobacterium leprae Probable pyruvate kinase PykA 0.0023 0.0009 0.0139
Brugia malayi intermediate filament protein 0.0017 0.0003 0.0003
Brugia malayi putative neuropeptide receptor 0.0135 0.0146 0.0145
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0083 0.0082 0.1204
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0564 0.0663 0.0663
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Mycobacterium tuberculosis Conserved protein 0.0038 0.0028 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0072 0.0069
Toxoplasma gondii ABC1 family protein 0.0038 0.0028 0.0033
Loa Loa (eye worm) translation initiation factor 4E 0.0056 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni cell adhesion molecule 0.0022 0.0008 0.0008
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.005
Onchocerca volvulus 0.0135 0.0146 0.2203
Schistosoma mansoni hypothetical protein 0.0545 0.064 0.064
Plasmodium vivax hypothetical protein 0.0545 0.064 0.9652
Loa Loa (eye worm) AGC/AKT protein kinase 0.0133 0.0143 0.0142
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0545 0.064 0.064
Echinococcus granulosus solute carrier family 5 0.0026 0.0013 0.0013
Trypanosoma brucei cAMP response protein 1, putative 0.0026 0.0013 0.001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0028 0.0894
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis serine threonine protein kinase 0.006 0.0055 0.0055
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0564 0.0663 1
Echinococcus multilocularis microtubule associated protein 2 0.0701 0.0829 0.0829
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus granulosus Tubulin beta 2C chain 0.0024 0.0012 0.0012
Echinococcus granulosus NDR protein kinase 0.0043 0.0034 0.0034
Schistosoma mansoni nephrin 0.0022 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0059 0.0054 0.0054
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.0115 0.0114
Loa Loa (eye worm) tubulin beta chain 0.0024 0.0012 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0015
Echinococcus granulosus FK506 binding protein 2 0.0023 0.001 0.001
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus granulosus fmrfamide receptor 0.0135 0.0146 0.0146
Brugia malayi larval opioid receptor 0.0135 0.0146 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.1588 0.1898 0.1896
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Onchocerca volvulus 0.0545 0.064 0.9703
Entamoeba histolytica hypothetical protein 0.0545 0.064 0.064
Onchocerca volvulus 0.0038 0.0028 0.0411
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0038 0.0537
Echinococcus multilocularis UNCoordinated family member (unc 13) 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0028 0.0424
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0018 0.0004 0.0001
Leishmania major protein kinase, putative 0.0027 0.0014 0.0014
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0603 0.071 0.0707
Onchocerca volvulus 0.0017 0.0003 0.0037
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1588 0.1898 0.1898
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0135 0.0146 0.2203
Echinococcus multilocularis synaptotagmin 2 0.0017 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0023 0.001 0.5
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0026 0.0013 0.0013
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0056 0.005 0.0047
Schistosoma mansoni myosin xvIII 0.0135 0.0146 0.0146
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.6618 0.7968 0.7968
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus granulosus tar DNA binding protein 0.0128 0.0137 0.0137
Onchocerca volvulus 0.0545 0.064 0.9703
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Giardia lamblia Histone acetyltransferase GCN5 0.0034 0.0023 0.0015
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0026 0.0013 0.0013
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2859 0.3433 0.3431
Mycobacterium ulcerans hypothetical protein 0.0026 0.0013 0.0425
Onchocerca volvulus 0.0135 0.0146 0.2203
Brugia malayi Cytochrome P450 family protein 0.0053 0.0046 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0121 0.0159
Echinococcus granulosus histone acetyltransferase KAT2B 0.0037 0.0027 0.0027
Schistosoma mansoni serine/threonine kinase 0.0043 0.0034 0.0034
Brugia malayi Protein kinase domain containing protein 0.0133 0.0143 0.0142
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0023 0.001 0.001
Entamoeba histolytica PH domain containing protein kinase, putative 0.0091 0.0092 0.0092
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis rac serine:threonine kinase 0.0091 0.0092 0.0092
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Giardia lamblia Beta tubulin 0.0024 0.0012 0.0003
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Plasmodium vivax glutathione reductase, putative 0.0038 0.0029 0.0389
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0545 0.064 0.064
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Echinococcus granulosus Protein kinase C brain isozyme 0.006 0.0055 0.0055
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0013 0.0014
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Brugia malayi nuclear hormone receptor 0.0016 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0023 0.001 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Schistosoma mansoni otoferlin 0.0017 0.0003 0.0003
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.0008 0.0008
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0016 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0034 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.4501 0.5414 0.5413
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.006 0.0055 0.0054
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0793 0.0939 0.0939
Echinococcus granulosus somatostatin receptor 0.0135 0.0146 0.0146
Chlamydia trachomatis glycogen phosphorylase 0.0212 0.0238 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.028 0.0321 0.0321
Schistosoma mansoni pyruvate kinase 0.0023 0.0009 0.0009
Echinococcus multilocularis neuroglian 0.0022 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Echinococcus granulosus importin subunit beta 1 0.0029 0.0018 0.0018
Mycobacterium ulcerans hypothetical protein 0.0026 0.0013 0.0425
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.1223 0.1458 0.1456
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0013 0.0014
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0564 0.0663 0.0887
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0016 0.0001 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Echinococcus granulosus synaptotagmin 0.0017 0.0003 0.0003
Echinococcus multilocularis calpain 5 0.0017 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Schistosoma mansoni cpg binding protein 0.0063 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus pyruvate kinase 0.0023 0.0009 0.0009
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0545 0.064 0.0856
Trypanosoma cruzi Flagellar Member 6 0.0026 0.0013 0.001
Leishmania major eukaryotic translation initiation factor-like 0.0056 0.005 0.005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0564 0.0663 0.0887
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0026 0.0013 0.0013
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.8301 1 1
Echinococcus granulosus nervana 2 0.0082 0.0081 0.0081
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0603 0.071 0.0707
Echinococcus granulosus lachesin 0.0022 0.0008 0.0008
Brugia malayi AKH receptor 0.0135 0.0146 0.0145
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0004 0.0001
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0026 0.0013 0.0201
Brugia malayi FAT domain containing protein 0.1223 0.1458 0.1458
Mycobacterium ulcerans transcriptional regulatory protein 0.0026 0.0013 0.0425
Trichomonas vaginalis adenylate cyclase type III, putative 0.0018 0.0004 0.0001
Echinococcus granulosus serine threonine protein kinase nrc 0.0083 0.0082 0.0082
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0135 0.0146 0.0146
Trichomonas vaginalis fk506-binding protein, putative 0.0023 0.001 0.0007
Entamoeba histolytica hypothetical protein, conserved 0.0017 0.0003 0.0002
Trichomonas vaginalis tubulin beta chain, putative 0.0024 0.0012 0.0009
Brugia malayi Thioredoxin reductase 0.0038 0.0029 0.0028
Echinococcus granulosus intersectin 2 0.0017 0.0003 0.0003
Echinococcus granulosus neuropeptide FF receptor 2 0.0135 0.0146 0.0146
Entamoeba histolytica protein kinase, putative 0.0125 0.0133 0.0132
Leishmania major cyclic nucleotide-binding protein-like protein 0.0026 0.0013 0.0013
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0081 0.008 0.0079
Trypanosoma brucei pyruvate kinase 1 0.0023 0.0009 0.0006
Echinococcus granulosus hyperpolarization activated cyclic 0.0039 0.0029 0.0029
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0028 0.0025
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.017 0.0187 0.6145
Loa Loa (eye worm) pyruvate kinase-PB 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0022 0.0008 0.0008
Entamoeba histolytica glycogen phosphorylase, putative 0.0092 0.0093 0.0092
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0039 0.0029 0.0028
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.2229 0.2672 0.267
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0146 0.0146
Schistosoma mansoni immunophilin 0.017 0.0187 0.0187
Entamoeba histolytica protein kinase, putative 0.0133 0.0143 0.0142
Trypanosoma brucei glucosidase, putative 0.0074 0.0072 0.0069
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0056 0.005 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0146 0.0146
Echinococcus granulosus neuropeptide receptor A26 0.0617 0.0727 0.0727
Echinococcus multilocularis hyperpolarization activated cyclic 0.0039 0.0029 0.0029
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0026 0.0013 0.0013
Echinococcus granulosus tachykinin peptides receptor 99D 0.0135 0.0146 0.0146
Brugia malayi ecdysteroid receptor 0.0016 0.0001 0.0001
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0083 0.0082 0.0082
Giardia lamblia Pyruvate kinase 0.0023 0.0009 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.001 0.001
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Echinococcus granulosus Tubulin beta 2C chain 0.0024 0.0012 0.0012
Echinococcus multilocularis roundabout 2 0.0059 0.0053 0.0053
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0056 0.005 0.0047
Echinococcus multilocularis Immunoglobulin 0.0037 0.0027 0.0027
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1598 0.1911 0.191
Echinococcus granulosus 7TM GPCR rhodopsin 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0135 0.0146 0.0146
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0313 0.036 0.036
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0037 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0028
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0135 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.01 0.1553
Schistosoma mansoni roundabout 0.0022 0.0008 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0183 0.0203 0.02
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0387 0.0387
Schistosoma mansoni cell adhesion molecule 0.0022 0.0008 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0011 0.0008
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.017 0.0187 0.2785
Schistosoma mansoni high-affinity choline transporter 0.0235 0.0265 0.0265
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0005
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0014 0.0014
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0026 0.0013 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0016 0.0001 0.0001
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0023 0.001 0.0154
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0137 0.0136
Schistosoma mansoni vesicular amine transporter 0.005 0.0042 0.0042
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Echinococcus multilocularis synaptotagmin protein 4 0.0017 0.0003 0.0003
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0024 0.0012 0.0012
Loa Loa (eye worm) copine family protein 0.0017 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0028 0.0025
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0026 0.0013 0.0013
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0545 0.064 0.064
Leishmania major protein kinase, putative 0.0027 0.0014 0.0014
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0545 0.064 0.0856
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0004 0.0001
Trypanosoma brucei cytochrome P450, putative 0.0023 0.001 0.0007
Echinococcus multilocularis ecdysone induced protein 78C 0.0016 0.0001 0.0001
Echinococcus multilocularis solute carrier family 5 0.0026 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Brugia malayi ORL1-like opioid receptor 0.0135 0.0146 0.0145
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0008 0.0008
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Entamoeba histolytica DENN domain protein 0.0017 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Toxoplasma gondii beta-tubulin, putative 0.0024 0.0012 0.0012
Onchocerca volvulus 0.0135 0.0146 0.2203
Schistosoma mansoni opsin-like receptor 0.0135 0.0146 0.0146
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0072 0.0072
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0545 0.064 0.9652
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis synaptotagmin 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.9652
Brugia malayi Synapse defective protein 1 0.0017 0.0003 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Brugia malayi beta-lactamase family protein 0.0038 0.0028 0.0027
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0026 0.0013 0.0013
Schistosoma mansoni glycogen phosphorylase 0.0092 0.0093 0.0093
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0013 0.001
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis orexin receptor type 2 0.0135 0.0146 0.0146
Loa Loa (eye worm) Nedd4-PD 0.0017 0.0003 0.0002
Mycobacterium ulcerans lipase LipD 0.0038 0.0028 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0007
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0014 0.0014
Trichomonas vaginalis adenylate cyclase type, putative 0.0018 0.0004 0.0001
Onchocerca volvulus 0.0135 0.0146 0.2203
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.017 0.0187 0.0187
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.9652
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0026 0.0013 0.0013
Trypanosoma brucei beta tubulin 0.0024 0.0012 0.0009
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0009 0.0009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0017 0.0003 0.0003
Echinococcus multilocularis expressed protein 0.0047 0.0038 0.0038
Onchocerca volvulus 0.0016 0.0001 0.0008
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0017 0.0003 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0037 0.0027 0.0027
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0013 0.001
Echinococcus multilocularis Protein kinase C, brain isozyme 0.006 0.0055 0.0055
Echinococcus granulosus sodium:glucose cotransporter 2 0.0026 0.0013 0.0013
Echinococcus granulosus protein kinase C gamma type 0.006 0.0055 0.0055
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0043 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0016 0.0001 0.0001
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0023 0.001 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.8301 1 1
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0081 0.008 0.1161
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0008 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0034 0.0023 0.002
Plasmodium vivax pyruvate kinase, putative 0.0023 0.0009 0.0098
Echinococcus granulosus allatostatin A receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0135 0.0146 0.0146
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0072 0.0072
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.8301 1 1
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.017 0.0187 0.0184
Giardia lamblia Hypothetical protein 0.0545 0.064 0.0633
Brugia malayi Egg laying defective protein 4 0.0027 0.0014 0.0014
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0056 0.005 0.005
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.017 0.0187 0.0179
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0024 0.0024
Echinococcus granulosus g-protein coupled receptor 0.0135 0.0146 0.0146
Echinococcus granulosus synaptotagmin 0.0017 0.0003 0.0003
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0017 0.0003 0.0002
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0023 0.001 0.001
Onchocerca volvulus 0.0194 0.0217 0.3276
Toxoplasma gondii LsmAD domain-containing protein 0.0034 0.0023 0.0027
Echinococcus granulosus geminin 0.028 0.0321 0.0321
Trichomonas vaginalis hypothetical protein 0.0018 0.0004 0.0001
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0009 0.0135
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0013 0.0201
Echinococcus granulosus expressed protein 0.0047 0.0038 0.0038
Echinococcus granulosus nervana 2 0.0082 0.0081 0.0081
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0729 0.0862 0.0861
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0024 0.0024
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.0113
Onchocerca volvulus 0.0135 0.0146 0.2203
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.6611 0.796 0.796
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.0638
Plasmodium falciparum thioredoxin reductase 0.0038 0.0029 0.0389
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0013
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Trichomonas vaginalis ran, putative 0.0022 0.0008 0.0005
Brugia malayi beta-tubulin, identical 0.0024 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0029 0.0028
Brugia malayi Copine VIII 0.0017 0.0003 0.0002
Giardia lamblia Glycogen phosphorylase 0.0212 0.0238 0.023
Leishmania major hypothetical protein, conserved 0.0038 0.0028 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0146 0.0146
Brugia malayi nuclear receptor NHR-88 0.0016 0.0001 0.0001
Trichomonas vaginalis adenylate cyclase type, putative 0.0018 0.0004 0.0001
Trichomonas vaginalis fk506-binding protein, putative 0.017 0.0187 0.0184
Trichomonas vaginalis tubulin epsilon chain, putative 0.0024 0.0012 0.0009
Plasmodium falciparum glutathione reductase 0.0038 0.0029 0.0389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0016 0.0001 0.0001
Echinococcus multilocularis Tubulin beta 2C chain 0.0024 0.0012 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Echinococcus granulosus microtubule associated protein 2 0.0701 0.0829 0.0829
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.6611 0.796 0.796
Onchocerca volvulus 0.0023 0.001 0.015
Echinococcus granulosus sex peptide receptor 0.0135 0.0146 0.0146
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0037 0.0027 0.0364
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0026 0.0013 0.0174
Brugia malayi Cyclic-nucleotide gated cation channel 0.0039 0.0029 0.0028
Brugia malayi Importin beta-1 subunit 0.0029 0.0018 0.0017
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0624 0.0735 0.0734
Loa Loa (eye worm) phosphatidylinositol 3 0.2821 0.3387 0.3386
Echinococcus multilocularis FTZ F1 alpha 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.017 0.0187 0.0184
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0014 0.0014
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0016 0.0015
Onchocerca volvulus 0.0038 0.0028 0.0411
Entamoeba histolytica protein kinase, putative 0.0018 0.0004 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.8301 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis pyruvate kinase 0.0023 0.0009 0.0009
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0013 0.001
Trichomonas vaginalis glutaminase, putative 0.0266 0.0304 0.0301
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0564 0.0663 0.0663
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0135 0.0146 0.0146
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0564 0.0663 0.0661
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0011 0.0008
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0545 0.064 0.064
Brugia malayi Tubulin beta-1 chain 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0028 0.0028
Schistosoma mansoni synaptotagmin-like protein 0.0017 0.0003 0.0003
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Schistosoma mansoni glycogen phosphorylase 0.0212 0.0238 0.0238
Echinococcus multilocularis copine 9 0.0017 0.0003 0.0003
Brugia malayi WW domain containing protein 0.0017 0.0003 0.0002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0008 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.0016 0.0001 0.0001
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans transmembrane transport protein 0.0026 0.0013 0.0425
Brugia malayi calpain 5 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis neuroglian 0.0046 0.0038 0.0038
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0008
Echinococcus granulosus neuropeptide s receptor 0.0617 0.0727 0.0727
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0146 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.001 0.0007
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0043 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0016 0.0013
Loa Loa (eye worm) beta-tubulin 0.0024 0.0012 0.0011
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Brugia malayi p70 ribosomal S6 kinase beta 0.0125 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni biogenic amine receptor 0.0135 0.0146 0.0146
Leishmania major c2 domain protein, putative 0.0017 0.0003 0.0002
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0016 0.0013
Toxoplasma gondii beta tubulin 0.0024 0.0012 0.0012
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis tubulin subunit beta 0.0024 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0137 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.8301 1 1
Brugia malayi Fibronectin type III domain containing protein 0.0037 0.0027 0.0026
Echinococcus multilocularis beta tubulin 0.0024 0.0012 0.0012
Echinococcus multilocularis neuropeptide receptor A26 0.0617 0.0727 0.0727
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0023 0.001 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.1042 0.124 0.124
Echinococcus multilocularis voltage gated potassium channel 0.0057 0.0051 0.0051
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0135 0.0146 0.2203
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0092 0.0093 0.3049
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0545 0.064 0.064
Brugia malayi Serotonin receptor 0.0135 0.0146 0.0145
Trypanosoma cruzi Protein kinase B 0.0091 0.0092 0.0089
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0024 0.0024
Schistosoma mansoni mctp-related 0.0017 0.0003 0.0003
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Schistosoma mansoni amine GPCR 0.0135 0.0146 0.0146
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0146 0.0146
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.8301 1 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0043 0.0034 0.0033
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.017 0.0187 0.0184
Echinococcus multilocularis roundabout 2 0.0022 0.0008 0.0008
Echinococcus multilocularis nervana 2 0.0082 0.0081 0.0081
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0057 0.0051 0.0051
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0135 0.0146 0.0145
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) CYP4Cod1 0.0023 0.001 0.001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0016 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0044 0.0041
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0017 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase type III, putative 0.0018 0.0004 0.0001
Entamoeba histolytica tubulin family protein 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Onchocerca volvulus 0.0017 0.0003 0.0037
Echinococcus multilocularis synaptotagmin 0.0017 0.0003 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0135 0.0146 0.0145
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0023 0.001 0.001
Entamoeba histolytica pyruvate kinase, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) intermediate filament protein 0.0017 0.0003 0.0003
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0023 0.001 0.001
Toxoplasma gondii TIM10 family protein, putative 0.0047 0.0038 0.0048
Entamoeba histolytica glycogen phosphorylase, putative 0.0212 0.0238 0.0238
Trichomonas vaginalis glycogen phosphorylase, putative 0.0212 0.0238 0.0235
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0004 0.0001
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0026 0.0013 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0545 0.064 0.9652
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0028 0.0025
Brugia malayi Peroxidasin 0.0022 0.0008 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0028 0.0025
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0135 0.0146 0.0146
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0083 0.0082 0.0082
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.001 0.0007
Schistosoma mansoni atypical protein kinase C 0.0043 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Brugia malayi hypothetical protein 0.0073 0.007 0.007
Leishmania major copine i-like protein 0.0017 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0016 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0016 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0072 0.0072
Brugia malayi LD23056p 0.0017 0.0003 0.0002
Echinococcus granulosus Tubulin beta 2C chain 0.0024 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.4961 0.5969 0.5968
Echinococcus multilocularis g-protein coupled receptor 0.0135 0.0146 0.0146
Schistosoma mansoni retinoic acid receptor RXR 0.0016 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Leishmania major pyruvate kinase 0.0023 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0038 0.0028 0.0894
Schistosoma mansoni 60S ribosomal protein L21 0.0031 0.0019 0.0019
Loa Loa (eye worm) glutaminase 0.0266 0.0304 0.0303
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0003 0.0003
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0004 0.0001
Echinococcus granulosus serine:threonine protein kinase N2 0.0043 0.0034 0.0034
Loa Loa (eye worm) beta-lactamase 0.0038 0.0028 0.0027
Leishmania major hypothetical protein, conserved 0.0043 0.0034 0.0034
Echinococcus granulosus active breakpoint cluster region 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0017 0.0003 0.0037
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1588 0.1898 0.1896
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0018 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0146 0.0146
Leishmania major phosphatidylinositol 3-kinase, putative 0.2811 0.3374 0.3374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0146 0.0146
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0135 0.0146 0.0146
Brugia malayi G-protein coupled receptor 0.0135 0.0146 0.0145
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0026 0.0013 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0072 0.0069
Brugia malayi glutaminase DH11.1 0.0266 0.0304 0.0303
Onchocerca volvulus Glycogen phosphorylase homolog 0.0212 0.0238 0.3606
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.067 0.079 0.0788
Loa Loa (eye worm) phosphatidylinositol 3 0.0545 0.064 0.064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0072 0.0069
Loa Loa (eye worm) synaptotagmin-1 0.0017 0.0003 0.0002
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.017 0.0187 0.0186
Giardia lamblia Beta tubulin 0.0024 0.0012 0.0003
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0024 0.0024
Leishmania major hypothetical protein, unknown function 0.0545 0.064 0.064
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0017 0.0003 0.0003
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2859 0.3433 0.3433
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0039 0.0029 0.0029
Echinococcus granulosus hyperpolarization activated cyclic 0.0039 0.0029 0.0029
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0008 0.0008
Echinococcus granulosus serine protein kinase ATM 0.1588 0.1898 0.1898
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.8301 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1588 0.1898 0.1898
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Plasmodium falciparum importin beta, putative 0.0029 0.0018 0.0222
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0039 0.0029 0.0029
Giardia lamblia Phosphatidylinositol 4-kinase 0.0545 0.064 0.0633
Loa Loa (eye worm) hypothetical protein 0.017 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.1588 0.1898 0.1896
Echinococcus granulosus dnaJ subfamily B 0.0844 0.1001 0.1001
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus granulosus serotonin receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis high affinity choline transporter 1 0.0235 0.0265 0.0265
Echinococcus granulosus cpg binding protein 0.0063 0.0058 0.0058
Echinococcus granulosus intermediate filament protein 0.0017 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0017 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase type, putative 0.0018 0.0004 0.0001
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0043 0.0034 0.0033
Trichomonas vaginalis tubulin alpha chain, putative 0.0024 0.0012 0.0009
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0729 0.0862 0.0859
Trypanosoma cruzi cAMP response protein 1, putative 0.0026 0.0013 0.001
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0056 0.005 0.005
Plasmodium falciparum ataxin-2 like protein, putative 0.0034 0.0023 0.03
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0545 0.064 0.0638
Trichomonas vaginalis PIKK family atypical protein kinase 0.4928 0.5929 0.5928
Loa Loa (eye worm) hypothetical protein 0.0059 0.0053 0.0052
Onchocerca volvulus Multiple C2 domain and transmembrane region protein homolog 0.0017 0.0003 0.0037
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0564 0.0663 0.0663
Schistosoma mansoni pyruvate kinase 0.0023 0.0009 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0016 0.0001 0.0001
Trypanosoma brucei trypanothione reductase 0.0038 0.0029 0.0026
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0564 0.0663 0.0663
Brugia malayi Sodium:solute symporter family protein 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Echinococcus multilocularis lysosomal alpha glucosidase 0.0336 0.0387 0.0387
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis protein kinase c epsilon type 0.006 0.0055 0.0055
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.01 0.1553
Schistosoma mansoni fer-1-related 0.0017 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0008 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0026 0.0013 0.0013
Echinococcus granulosus defective proboscis extension response 0.0037 0.0027 0.0027
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0017 0.0003 0.0002
Schistosoma mansoni biogenic amine receptor 0.0135 0.0146 0.0146
Leishmania major phosphatidylinositol 3-kinase, putative 0.0564 0.0663 0.0663
Schistosoma mansoni fk506 binding protein 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0022
Schistosoma mansoni septate junction protein 0.0022 0.0008 0.0008
Echinococcus granulosus protein kinase c iota type 0.0043 0.0034 0.0034
Echinococcus multilocularis hemicentin 1 0.0022 0.0008 0.0008
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0896 0.1063 0.1063
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Schistosoma mansoni importin beta-1 0.0029 0.0018 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0034 0.0023 0.002
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Plasmodium falciparum tubulin beta chain 0.0024 0.0012 0.0132
Onchocerca volvulus 0.0038 0.0028 0.0411
Loa Loa (eye worm) hypothetical protein 0.0075 0.0073 0.0072
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0058 0.0052 0.0049
Toxoplasma gondii pyruvate kinase PyK1 0.0023 0.0009 0.0009
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.001 0.0002
Trichomonas vaginalis fk506 binding protein, putative 0.0023 0.001 0.0007
Echinococcus multilocularis pyruvate kinase 0.0023 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0235 0.0265 0.0265
Mycobacterium tuberculosis Conserved hypothetical protein 0.0545 0.064 1
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus synaptotagmin 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0135 0.0146 0.0146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0016 0.0001 0.0001
Trypanosoma brucei beta tubulin 0.0024 0.0012 0.0009
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.017 0.0187 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0034 0.0023 0.0307
Onchocerca volvulus 0.0059 0.0054 0.0808
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1588 0.1898 0.1896
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0072 0.0069
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis active breakpoint cluster region 0.0017 0.0003 0.0003
Entamoeba histolytica acetyltransferase, GNAT family 0.0034 0.0023 0.0023
Echinococcus multilocularis serotonin receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0026 0.0013 0.001
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0039 0.0029 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0028 0.0028
Brugia malayi acetyltransferase, GNAT family protein 0.0126 0.0134 0.0134
Brugia malayi G protein-coupled receptor F59B2.13 0.0135 0.0146 0.0145
Brugia malayi RNA binding protein 0.0128 0.0137 0.0136
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0026 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0026 0.0013 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0016 0.0001 0.0001
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0729 0.0862 0.0859
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus granulosus neuropeptide receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0019 0.0005 0.0002
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0011 0.0008
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0026 0.0013 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0016 0.0001 0.0001
Brugia malayi neuropeptide F receptor 0.0135 0.0146 0.0145
Schistosoma mansoni voltage-gated potassium channel 0.0057 0.0051 0.0051
Schistosoma mansoni synaptotagmin 0.0017 0.0003 0.0003
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0013 0.0012
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0026 0.0013 0.0159
Echinococcus multilocularis 0.0545 0.064 0.064
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.001 0.0002
Toxoplasma gondii FATC domain-containing protein 0.1588 0.1898 0.2547
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0011 0.0008
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0072 0.0093
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.6611 0.796 0.796
Treponema pallidum catabolite gene activator (Crp) 0.0026 0.0013 0.017
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.0146 0.0146
Leishmania major c2 domain protein, putative 0.0017 0.0003 0.0002
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0056 0.005 0.005
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0018 0.0004 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0023 0.001 0.015
Echinococcus multilocularis expressed conserved protein 0.0027 0.0014 0.0014
Plasmodium vivax importin-beta 2, putative 0.0029 0.0018 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0143 0.014
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0088 0.0088 0.1369
Echinococcus multilocularis Tubulin beta 2C chain 0.0024 0.0012 0.0012
Trypanosoma brucei protein kinase A regulatory subunit 0.0026 0.0013 0.001
Schistosoma mansoni cpg binding protein 0.0063 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.017 0.0187 0.0184
Brugia malayi Hr1 repeat family protein 0.0043 0.0034 0.0033
Echinococcus multilocularis sex peptide receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0146 0.0146
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0016 0.0231
Schistosoma mansoni hypothetical protein 0.1223 0.1458 0.1458
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0004 0.0001
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0026 0.0013 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0545 0.064 0.064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0001 0.0001
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0023 0.001 0.001
Echinococcus multilocularis protein piccolo 0.0017 0.0003 0.0003
Mycobacterium leprae Probable lipase LipE 0.0038 0.0028 0.0424
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Echinococcus granulosus synaptotagmin 2 0.0017 0.0003 0.0003
Loa Loa (eye worm) BEN-1 protein 0.0024 0.0012 0.0011
Onchocerca volvulus Protein ultraspiracle homolog 0.0016 0.0001 0.0008
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0126 0.0134 0.0134
Loa Loa (eye worm) melatonin receptor type 1A 0.0135 0.0146 0.0145
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0564 0.0663 0.0663
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0603 0.071 0.0707
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0135 0.0146 0.0146
Echinococcus granulosus tubulin subunit beta 0.0024 0.0012 0.0012
Brugia malayi hypothetical protein 0.0037 0.0027 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0146 0.0146
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0056 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.6185 0.7446 0.7445
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0009 0.0006
Trichomonas vaginalis glycogen phosphorylase, putative 0.0212 0.0238 0.0235
Entamoeba histolytica hypothetical protein 0.0545 0.064 0.064
Echinococcus granulosus protein piccolo 0.0017 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0055 0.0055
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0026 0.0013 0.0013
Schistosoma mansoni opsin-like receptor 0.0135 0.0146 0.0146
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0039 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.036 0.0359
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Brugia malayi NEDD4.2 0.0017 0.0003 0.0002
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0545 0.064 0.0638
Echinococcus granulosus patatin phospholipase domain containing protein 0.0026 0.0013 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0004 0.0001
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0026 0.0013 0.0013
Entamoeba histolytica glycogen phosphorylase, putative 0.0212 0.0238 0.0238
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0545 0.064 0.0856
Schistosoma mansoni voltage-gated potassium channel 0.0213 0.024 0.024
Entamoeba histolytica glycogen phosphorylase, putative 0.0092 0.0093 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0631 0.0744 0.0736
Loa Loa (eye worm) phosphatidylinositol 3 0.0545 0.064 0.064
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0137 0.0137
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2859 0.3433 0.3433
Echinococcus granulosus beta tubulin 0.0024 0.0012 0.0012
Schistosoma mansoni intermediate filament proteins 0.0017 0.0003 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0057 0.0051 0.005
Echinococcus granulosus synaptotagmin 15 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0023 0.0009 0.0139
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0008 0.0008
Brugia malayi protein kinase C II. 0.006 0.0055 0.0054
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2859 0.3433 0.3433
Loa Loa (eye worm) AGC/PKG protein kinase 0.0027 0.0014 0.0014
Schistosoma mansoni rabphilin-3a 0.0017 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0601 0.0708 0.0707
Loa Loa (eye worm) TYRA-2 protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0088 0.0088 0.1369
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.6611 0.796 0.796
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0603 0.071 0.0707
Onchocerca volvulus 0.0026 0.0013 0.0196
Brugia malayi Glycosyl hydrolases family 31 protein 0.0336 0.0387 0.0387
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0072 0.0069
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0026 0.0026
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0545 0.064 0.064
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Entamoeba histolytica hypothetical protein 0.1588 0.1898 0.1898
Schistosoma mansoni steroid hormone receptor ad4bp 0.0016 0.0001 0.0001
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0001 0.0001
Trypanosoma cruzi target of rapamycin kinase 3 0.6618 0.7968 0.7968
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0601 0.0708 0.0707
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0004 0.0004
Leishmania major hypothetical protein, unknown function 0.0026 0.0013 0.0013
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0018 0.0004 0.0001
Onchocerca volvulus 0.0135 0.0146 0.2203
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0545 0.064 0.9652
Brugia malayi GH02984p 0.0235 0.0265 0.0265
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0026 0.0013 0.0013
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0017 0.0003 0.0003
Brugia malayi Synaptotagmin protein 3 0.0017 0.0003 0.0002
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0026 0.0013 0.0013
Echinococcus multilocularis serine:threonine protein kinase 38 0.0043 0.0034 0.0034
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.3919 0.4712 0.471
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0146 0.0146
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0009 0.0135
Echinococcus granulosus neuroglian 0.0022 0.0008 0.0008
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1588 0.1898 0.1898
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0038 0.0537
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0545 0.064 0.064
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0603 0.071 0.0709
Echinococcus granulosus neuroglian 0.0046 0.0038 0.0038
Mycobacterium ulcerans beta-lactamase 0.0038 0.0028 0.0894
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0564 0.0663 0.0663
Onchocerca volvulus 0.0135 0.0146 0.2203
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.5388 0.6484 0.6483
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0037 0.0027 0.0032
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.001
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0039 0.0029 0.0029
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.8301 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0137 0.0137
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0009 0.0006
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis 0.0017 0.0003 0.0003
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0035 0.0024 0.0024
Loa Loa (eye worm) tubulin beta-2A chain 0.0024 0.0012 0.0011
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2821 0.3387 0.3385
Echinococcus granulosus sodium:myo inositol cotransporter 0.0026 0.0013 0.0013
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.0272 0.4244
Leishmania major fk506-binding protein 1-like protein 0.017 0.0187 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0016 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0564 0.0663 0.0661
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0195 0.0218 0.0218
Schistosoma mansoni serine/threonine-protein kinase 0.0092 0.0093 0.0093
Echinococcus granulosus Tubulin beta 2C chain 0.0024 0.0012 0.0012
Schistosoma mansoni neuropeptide receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0016 0.0001 0.0001
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0042 0.0033 0.003
Loa Loa (eye worm) tubulin beta-4 chain 0.0024 0.0012 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.2811 0.3374 0.3372
Giardia lamblia Beta tubulin 0.0024 0.0012 0.0003
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0026 0.0013 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.001
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.001 0.0002
Onchocerca volvulus Tyrosine kinase homolog 0.0562 0.066 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0135 0.0146 0.0145
Treponema pallidum cyclic nucleotide binding protein 0.0026 0.0013 0.017
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Echinococcus multilocularis copine 9 0.0017 0.0003 0.0003
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Leishmania major phospholipase c-like protein 0.0017 0.0003 0.0002
Brugia malayi follicle stimulating hormone receptor 0.0135 0.0146 0.0145
Echinococcus multilocularis cpg binding protein 0.0063 0.0058 0.0058
Echinococcus granulosus g protein coupled receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis hemicentin 1 0.0022 0.0008 0.0008
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0134 0.0134
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0028 0.0424
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0135 0.0146 0.0146
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0016 0.0001 0.0001
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.017 0.0187 0.0184
Echinococcus granulosus copine 9 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0026 0.0013 0.0201
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Trypanosoma brucei pyruvate kinase 1, putative 0.0023 0.0009 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0844 0.1001 0.1001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0545 0.064 0.0638
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0029 0.0029
Schistosoma mansoni RAR-like nuclear receptor 0.0016 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0034 0.0031
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0013 0.001
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0896 0.1063 0.1063
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.017 0.0187 0.2785
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Mycobacterium ulcerans hypothetical protein 0.0026 0.0013 0.0425
Entamoeba histolytica C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0028 0.0028
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0018 0.0004 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1588 0.1898 0.1898
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0057 0.0051 0.005
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.2811 0.3374 0.3372
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0026 0.0013 0.0013
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0146 0.0146
Echinococcus multilocularis unc 13 (munc13) 0.0017 0.0003 0.0003
Schistosoma mansoni nedd-4-like E3 ubiquitin-protein ligase 0.0017 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.017 0.0187 0.0184
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0028 0.0025
Leishmania major phosphatidylinositol 4-kinase, putative 0.0545 0.064 0.064
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.067 0.079 0.0788
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Brugia malayi G protein-coupled receptor 0.0135 0.0146 0.0145
Trypanosoma brucei beta tubulin 0.0024 0.0012 0.0009
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.8301 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0135 0.0146 0.0145
Echinococcus granulosus calpain 5 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0135 0.0146 0.2203
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0029 0.0029
Echinococcus granulosus dro:myosuppressin receptor 0.0135 0.0146 0.0146
Trypanosoma brucei target of rapamycin kinase 3, putative 0.6618 0.7968 0.7968
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0088 0.0088 0.1369
Schistosoma mansoni amine GPCR 0.0135 0.0146 0.0146
Echinococcus granulosus peroxidasin 0.0022 0.0008 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.0146 0.0146
Echinococcus multilocularis serotonin receptor 0.0135 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.8301 1 1
Onchocerca volvulus 0.0549 0.0644 0.9766
Schistosoma mansoni immunophilin 0.0146 0.0159 0.0159
Trypanosoma cruzi PAB1-binding protein , putative 0.0034 0.0023 0.002
Brugia malayi C2 domain containing protein 0.0017 0.0003 0.0002
Echinococcus granulosus tubulin beta 4A class IVa 0.0024 0.0012 0.0012
Echinococcus multilocularis lamin dm0 0.0017 0.0003 0.0003
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0146 0.0159 0.0158
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0018 0.0004 0.0001
Echinococcus multilocularis Tubulin beta 2C chain 0.0024 0.0012 0.0012
Echinococcus multilocularis synaptotagmin 0.0017 0.0003 0.0003
Trypanosoma brucei beta tubulin 0.0024 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Schistosoma mansoni inositol transporter 0.0026 0.0013 0.0013
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0564 0.0663 0.0661
Echinococcus multilocularis intersectin 2 0.0017 0.0003 0.0003
Loa Loa (eye worm) C2 domain-containing protein 0.0017 0.0003 0.0002
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0013 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0028 0.0025
Echinococcus granulosus orexin receptor type 2 0.0135 0.0146 0.0146
Trypanosoma cruzi cAMP response protein 1 0.0026 0.0013 0.001
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0004 0.0001
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0072 0.0072
Leishmania major phosphatidylinositol kinase, putative 0.0545 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0026 0.0013 0.001
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Brugia malayi putative neuropeptide receptor NPR1 0.0135 0.0146 0.0145
Echinococcus multilocularis Immunoglobulin 0.0037 0.0027 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0213 0.024 0.024
Schistosoma mansoni fkbp-rapamycin associated protein 0.1588 0.1898 0.1898
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0027
Echinococcus granulosus protein kinase c epsilon type 0.006 0.0055 0.0055
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Echinococcus multilocularis glycogen phosphorylase 0.0212 0.0238 0.0238
Brugia malayi Protein kinase domain containing protein 0.0043 0.0034 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0008
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0026 0.0013 0.0014
Echinococcus multilocularis lamin 0.0017 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.001 0.0325
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0039 0.0029 0.0029
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.1223 0.1458 0.1458
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0072 0.0069
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0026 0.0013 0.001
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0026 0.0013 0.0195
Echinococcus granulosus beta tubulin 0.0024 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.008 0.0079
Echinococcus granulosus single minded 2 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0036 0.0026 0.0025
Schistosoma mansoni alpha-glucosidase 0.0289 0.0331 0.0331
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0026 0.0013 0.0159
Entamoeba histolytica protein kinase 2, putative 0.0083 0.0082 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi Pyruvate kinase, M2 isozyme 0.0023 0.0009 0.0009
Schistosoma mansoni neuroglian 0.0022 0.0008 0.0008
Brugia malayi hypothetical protein 0.0034 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0662 0.0781 0.0781
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0545 0.064 0.064
Schistosoma mansoni tubulin subunit beta 0.0024 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0081 0.008 0.0103
Echinococcus multilocularis Tubulin beta 2C chain 0.0024 0.0012 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0037 0.0027 0.0024
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.017 0.0187 0.0187
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0082 0.0081 0.0081
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0729 0.0862 0.0859
Schistosoma mansoni hypothetical protein 0.0035 0.0024 0.0024
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0028 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0146 0.0146
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0023 0.001 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.0058 0.0052 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.4494 0.5406 0.5404
Trichomonas vaginalis PIKK family atypical protein kinase 0.0545 0.064 0.0638
Echinococcus multilocularis roundabout 2 0.0022 0.0008 0.0008
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0896 0.1063 0.1063
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0028 0.0374
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni cell adhesion molecule 0.0049 0.0041 0.0041
Schistosoma mansoni copine 0.0017 0.0003 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0146 0.0146
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0146 0.0146
Mycobacterium tuberculosis Probable reductase 0.0088 0.0088 0.1369
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0088 0.0088 0.1369
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0016 0.0013
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2821 0.3387 0.3386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0026 0.0026
Brugia malayi Dopamine receptor 0.0135 0.0146 0.0145
Brugia malayi hypothetical protein 0.0073 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi photoreceptor-specific nuclear receptor 0.0016 0.0001 0.0001
Echinococcus granulosus pyruvate kinase 0.0023 0.0009 0.0009
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0056 0.005 0.0064
Schistosoma mansoni histamine h1 receptor 0.0135 0.0146 0.0146
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.0115 0.0114
Leishmania major beta tubulin 0.0024 0.0012 0.0011
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0545 0.064 0.0638
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.017 0.0187 0.0186
Leishmania major regulatory subunit of protein kinase a-like protein 0.0026 0.0013 0.0013
Echinococcus multilocularis synaptotagmin 15 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1042 0.124 0.1238
Leishmania major hypothetical protein, conserved 0.0034 0.0023 0.0022
Brugia malayi RE15519p 0.0135 0.0146 0.0145
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0013 0.0201
Toxoplasma gondii thioredoxin reductase 0.0038 0.0029 0.0035
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0023 0.001 0.0043
Echinococcus multilocularis G protein coupled receptor 139 0.0135 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.4928 0.5929 0.5928
Echinococcus granulosus 7tm_1 domain containing protein 0.0135 0.0146 0.0146
Plasmodium falciparum cGMP-dependent protein kinase 0.0027 0.0014 0.0175
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0017 0.0003 0.0003
Brugia malayi beta-lactamase 0.0038 0.0028 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0146 0.0146
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0146 0.0146
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0043 0.0034 0.0033
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.01 0.1553
Echinococcus granulosus G protein coupled receptor 139 0.0135 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0135 0.0146 0.0145
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0009 0.0009
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0017 0.0003 0.0037

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 0 % In vitro agonist activity relative to angiotensin II measured in rabbit aorta strip assay. ChEMBL. 1920354
Activity (functional) = 5 % In vivo agonist activity expressed as percent activity relative to angiotensin II in rat blood pressure assay. ChEMBL. 1920354
ID50 (functional) = 1000 ng min-1 rat-1 In vivo antagonist activity (ANG II like) expressed by blood pressure increase(mHg)produced by 1 mg bolus iv injection of compound in rats ChEMBL. 1920354
Kd (functional) = 7.5 In vitro antagonist activity (ANG II like) expressed as percent activity relative to ANG II in rabbit aorta strip assay. ChEMBL. 1920354

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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