Detailed information for compound 406420

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1614.81 | Formula: C71H99N21O19S2
  • H donors: 22 H acceptors: 20 LogP: -2.54 Rotable bonds: 28
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2c[nH]cn2)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)Cc1c[nH]c2c1cccc2)CCC(=O)N)CC(=O)O)Cc1c[nH]c2c1cccc2)C(=O)N[C@H](C(=O)O)[C@H](O)C)NC(=O)C)C
  • InChi: 1S/C71H99N21O19S2/c1-8-34(4)57(82-37(7)94)69(109)90-52-31-113-112-30-51(67(107)92-58(36(6)93)70(110)111)89-61(101)45(18-13-21-76-71(73)74)83-64(104)49(24-40-28-75-32-80-40)85-59(99)35(5)81-54(96)29-79-60(100)47(22-38-26-77-43-16-11-9-14-41(38)43)86-65(105)50(25-55(97)98)87-62(102)46(19-20-53(72)95)84-63(103)48(88-68(108)56(33(2)3)91-66(52)106)23-39-27-78-44-17-12-10-15-42(39)44/h9-12,14-17,26-28,32-36,45-52,56-58,77-78,93H,8,13,18-25,29-31H2,1-7H3,(H2,72,95)(H,75,80)(H,79,100)(H,81,96)(H,82,94)(H,83,104)(H,84,103)(H,85,99)(H,86,105)(H,87,102)(H,88,108)(H,89,101)(H,90,109)(H,91,106)(H,92,107)(H,97,98)(H,110,111)(H4,73,74,76)/t34-,35-,36+,45-,46-,47-,48-,49+,50+,51-,52-,56-,57-,58-/m0/s1
  • InChiKey: XVHYFABBPDIZAN-YEKOCRBCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens complement component 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major protein kinase, putative 0.0036 0.0034 0.0067
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0022 0.0013 0.0094
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0008 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.005
Brugia malayi beta-lactamase 0.01 0.0134 0.0257
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0037 0.0069
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0034 0.0031 0.0038
Onchocerca volvulus 0.0029 0.0024 0.0178
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0024 0.0016 0.0016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0016 0.0032
Brugia malayi Receptor family ligand binding region containing protein 0.002 0.001 0.0017
Brugia malayi A-macroglobulin complement component family protein 0.0021 0.0011 0.0019
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0024 0.0043
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0016 0.0003 0.0002
Brugia malayi Metabotropic glutamate receptor precursor. 0.008 0.0103 0.0197
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Onchocerca volvulus 0.0029 0.0024 0.0178
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0005 0.0007
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0027 0.002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0115 0.0156 0.0206
Schistosoma mansoni ets 0.0043 0.0045 0.0044
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus granulosus mitogen activated protein kinase 11 0.3325 0.5142 0.6885
Onchocerca volvulus 0.01 0.0134 0.1123
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0047 0.0052 0.0363
Loa Loa (eye worm) DIX domain-containing protein 0.0037 0.0037 0.0069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0023
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Brugia malayi Ets-domain containing protein 0.0294 0.0435 0.0842
Schistosoma mansoni heat shock protein 0.0168 0.0239 0.0239
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0013 0.0101
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.01 0.0134 0.0941
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0024 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0028
Trichomonas vaginalis ras GTP exchange factor, putative 0.0027 0.002 0.014
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0473 0.0713 0.1384
Loa Loa (eye worm) steroid hormone receptor 0.0489 0.0738 0.1434
Echinococcus multilocularis mitogen activated protein kinase 0.0063 0.0077 0.0099
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0024 0.0016 0.0032
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0024 0.0023
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0016 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0027 0.002 0.0141
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.0093 0.0121
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0013 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0013 0.0106
Trypanosoma brucei Heat shock protein 83, putative 0.0168 0.0239 0.0465
Brugia malayi AKH receptor 0.0029 0.0024 0.0043
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0072 0.009 0.0117
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0036 0.0034 0.0042
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0024 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.01 0.0134 0.0133
Entamoeba histolytica acetyltransferase, GNAT family 0.0123 0.017 0.1196
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0016 0.0003 0.002
Schistosoma mansoni smad1 5 8 and 0.0044 0.0047 0.0047
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0489 0.0738 0.0986
Schistosoma mansoni titin 0.0019 0.0007 0.0007
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0134 0.0186 0.0523
Brugia malayi MH2 domain containing protein 0.0044 0.0047 0.0089
Loa Loa (eye worm) hypothetical protein 0.0259 0.038 0.0737
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0022 0.0013 0.0022
Brugia malayi Importin beta-1 subunit 0.0033 0.003 0.0055
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0024 0.0023
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0067 0.0083 0.0107
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0071 0.0707
Brugia malayi GH02984p 0.1039 0.1591 0.3092
Echinococcus granulosus PWWP domain containing protein 2A 0.0019 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0041 0.029
Loa Loa (eye worm) transcription factor SMAD2 0.065 0.0987 0.1918
Schistosoma mansoni cpg binding protein 0.0149 0.0209 0.0209
Onchocerca volvulus 0.0029 0.0024 0.0178
Toxoplasma gondii ABC1 family protein 0.01 0.0134 0.1388
Mycobacterium ulcerans transcriptional regulatory protein 0.0022 0.0013 0.0093
Schistosoma mansoni cpg binding protein 0.0157 0.0222 0.0222
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.002 0.0039
Schistosoma mansoni coup transcription factor 0.0489 0.0738 0.0738
Echinococcus multilocularis twitchin 0.0016 0.0004 0.0001
Trichomonas vaginalis DNA topoisomerase II, putative 0.0034 0.0031 0.0222
Schistosoma mansoni aminopeptidase A (M01 family) 0.0024 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0069
Echinococcus granulosus metabotropic glutamate receptor 2 0.0067 0.0082 0.0107
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0016 0.0032
Toxoplasma gondii DNA topoisomerase 2, putative 0.0034 0.0031 0.0294
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0013 0.0106
Entamoeba histolytica protein kinase, putative 0.0018 0.0006 0.004
Brugia malayi nuclear hormone receptor family member odr-7 0.0231 0.0337 0.0652
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0013 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0489 0.0738 0.1434
Echinococcus multilocularis short transient receptor potential channel 6 0.0128 0.0178 0.0234
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0008 0.0015
Brugia malayi metabotropic glutamate receptor type 2 0.0039 0.0039 0.0073
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0039 0.0049
Brugia malayi jmjC domain containing protein 0.0083 0.0107 0.0204
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0019
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0625 0.0949 0.1846
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus granulosus cGMP dependent protein kinase 0.0036 0.0034 0.0042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0024
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0013 0.0106
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0024 0.0023
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0489 0.0738 0.0986
Echinococcus multilocularis dna polymerase eta 0.0162 0.0229 0.0303
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Echinococcus granulosus solute carrier family 5 0.0115 0.0156 0.0206
Brugia malayi hypothetical protein 0.0037 0.0037 0.0068
Echinococcus granulosus FTZ F1 alpha 0.0489 0.0738 0.0986
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.002 0.0009 0.0008
Schistosoma mansoni 6-phosphofructokinase 0.022 0.032 0.032
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0869 0.1328 0.2582
Schistosoma mansoni nuclear receptor 0.0231 0.0337 0.0337
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0057 0.0067 0.047
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0024 0.0028
Brugia malayi Egg laying defective protein 4 0.0036 0.0034 0.0064
Echinococcus multilocularis heat shock protein 0.0168 0.0239 0.0316
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0134 0.0186 0.1889
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.009 0.0117
Loa Loa (eye worm) RasGEF domain-containing protein 0.0027 0.002 0.0036
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0022 0.0013 0.1235
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0029 0.0024 0.0043
Echinococcus granulosus heat shock protein 0.0168 0.0239 0.0316
Loa Loa (eye worm) DR-78 0.0231 0.0337 0.0653
Schistosoma mansoni SET domain protein 0.0036 0.0034 0.0034
Toxoplasma gondii aminopeptidase N, putative 0.0618 0.0938 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0022 0.0013 0.0094
Leishmania major cytochrome p450-like protein 0.0023 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0259 0.038 0.0737
Onchocerca volvulus 0.0029 0.0024 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.032 0.2252
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0134 0.0187 0.1961
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0023
Entamoeba histolytica hypothetical protein, conserved 0.0625 0.0949 0.6686
Brugia malayi Nuclear hormone receptor-like 1 0.0489 0.0738 0.1433
Brugia malayi ephrin receptor 1 precursor 0.0033 0.0029 0.0053
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0013 0.0106
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0936 0.1433 0.1916
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0186 0.1309
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0035 0.0033 0.0041
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0071 0.0714
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma brucei DNA damage repair protein, putative 0.005 0.0056 0.0109
Loa Loa (eye worm) CAMK protein kinase 0.0019 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0056
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0033 0.0232
Schistosoma mansoni gabp alpha 0.0294 0.0435 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0489 0.0738 0.1433
Schistosoma mansoni hypothetical protein 0.0541 0.0818 0.0818
Onchocerca volvulus 0.0029 0.0024 0.0178
Trichomonas vaginalis penicillin-binding protein, putative 0.01 0.0134 0.0941
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0027 0.0032
Brugia malayi orphan nuclear receptor NR2E1 0.0231 0.0337 0.0652
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0023
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0022 0.0012 0.0021
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0024 0.0023
Giardia lamblia DINP protein human, muc B family 0.0162 0.0229 0.1569
Onchocerca volvulus Alhambra homolog 0.0061 0.0073 0.0606
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0259 0.038 0.0737
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0366 0.0547 0.0729
Loa Loa (eye worm) phosphofructokinase 0.022 0.032 0.062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0134 0.0187 0.1318
Entamoeba histolytica deoxycytidyl transferase, putative 0.0162 0.0229 0.1614
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.01 0.0134 0.1478
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0029
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0022 0.0013 0.0013
Trypanosoma brucei cAMP binding protein, putative 0.0022 0.0013 0.0025
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0009 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus neuropeptide receptor 0.0029 0.0024 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Echinococcus multilocularis Smad4 0.0044 0.0047 0.0059
Toxoplasma gondii heat shock protein 75, putative 0.0069 0.0085 0.0869
Echinococcus multilocularis segment polarity protein dishevelled 0.0037 0.0037 0.0045
Echinococcus granulosus TGF beta signal transducer SmadC 0.0044 0.0047 0.0059
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0037 0.0036
Schistosoma mansoni dep domain containing protein 0.0037 0.0037 0.0036
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0013 0.0101
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0016 0.0003 0.0003
Trypanosoma cruzi heat shock protein 85, putative 0.0168 0.0239 0.0465
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0013 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0162 0.0229 0.0443
Mycobacterium ulcerans 6-phosphofructokinase 0.022 0.032 0.3611
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0016 0.0003 0.0002
Treponema pallidum cyclic nucleotide binding protein 0.0022 0.0013 0.0037
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.022 0.032 0.3274
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0024 0.0043
Schistosoma mansoni Smad4 0.002 0.0009 0.0009
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0013 0.0101
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0034 0.0031 0.0246
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0013 0.0101
Leishmania major importin beta-1 subunit, putative 0.0027 0.002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0073 0.0092 0.0178
Schistosoma mansoni terminal deoxycytidyl transferase 0.0162 0.0229 0.0229
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0067 0.0083 0.0835
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0027 0.002 0.002
Echinococcus granulosus roundabout 2 0.0017 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus transient receptor potential gamma protein 0.0193 0.0278 0.0368
Brugia malayi beta-lactamase family protein 0.01 0.0134 0.0257
Brugia malayi Stress-activated protein kinase jnk-1 0.0473 0.0713 0.1383
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0231 0.0337 0.0337
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0034 0.0031 0.0061
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0024 0.0178
Trichomonas vaginalis glutaminase, putative 0.0579 0.0877 0.6179
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0366 0.0547 0.1061
Echinococcus granulosus dna polymerase kappa 0.0162 0.0229 0.0303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trichomonas vaginalis rotamase, putative 0.0035 0.0033 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) heat shock protein 75 0.0069 0.0085 0.0163
Mycobacterium ulcerans hypothetical protein 0.005 0.0056 0.0592
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0072 0.009 0.0117
Echinococcus granulosus titin 0.0019 0.0007 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0489 0.0738 0.0986
Echinococcus multilocularis beta LACTamase domain containing family member 0.01 0.0134 0.0175
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Mycobacterium tuberculosis Probable lipase LipE 0.01 0.0134 0.1349
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0023
Trypanosoma brucei DNA topoisomerase ii 0.0034 0.0031 0.0061
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.1039 0.1591 0.3093
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0047 0.0052 0.0097
Schistosoma mansoni vesicular amine transporter 0.0018 0.0007 0.0007
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0029 0.0024 0.021
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0053
Echinococcus granulosus sentrin specific protease 1 0.0047 0.0052 0.0065
Loa Loa (eye worm) histone methyltransferase 0.0051 0.0058 0.011
Brugia malayi N-terminal motif family protein 0.0027 0.002 0.0036
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.009 0.0117
Loa Loa (eye worm) jmjC domain-containing protein 0.0083 0.0107 0.0205
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.022 0.032 0.221
Echinococcus granulosus mitogen activated protein kinase 3 0.0063 0.0077 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0109 0.0109
Schistosoma mansoni DNA polymerase eta 0.0162 0.0229 0.0229
Brugia malayi Melatonin receptor type 1A 0.0029 0.0024 0.0043
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0024 0.0016 0.0115
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0013 0.0106
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0034 0.0031 0.0061
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0013 0.0026
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0009 0.0018
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0073 0.0095
Echinococcus multilocularis mothers against decapentaplegic 6 0.002 0.0009 0.0008
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0016 0.0003 0.0003
Brugia malayi hypothetical protein 0.0019 0.0008 0.0013
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0489 0.0738 0.0738
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0231 0.0337 0.0652
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0016 0.0029
Brugia malayi ecdysone receptor 0.0231 0.0337 0.0652
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0016 0.0131
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0489 0.0738 0.0738
Plasmodium falciparum ataxin-2 like protein, putative 0.0129 0.0179 0.1877
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0259 0.038 0.038
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0009 0.0018
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0022 0.0013 0.0022
Mycobacterium ulcerans lipase LipD 0.01 0.0134 0.1478
Echinococcus granulosus GPCR family 2 0.0306 0.0454 0.0604
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0489 0.0738 0.1434
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0008 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0024 0.0043
Echinococcus multilocularis ETS transcription factor Elf 2 0.0043 0.0045 0.0056
Brugia malayi steroid hormone receptor 0.0489 0.0738 0.1433
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0024 0.0023
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0024 0.0028
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0077 0.0542
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0024 0.0023
Brugia malayi hypothetical protein 0.0608 0.0923 0.1792
Schistosoma mansoni transient receptor potential channel 4 0.0193 0.0278 0.0277
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Brugia malayi MAP kinase sur-1 0.0063 0.0077 0.0147
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Onchocerca volvulus 0.0032 0.0028 0.0212
Schistosoma mansoni Smad4 0.0044 0.0047 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0072 0.009 0.0636
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0008
Schistosoma mansoni cpg binding protein 0.0157 0.0222 0.0222
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0039 0.0076
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0024 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0013 0.0102
Loa Loa (eye worm) hypothetical protein 0.0035 0.0033 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0023
Schistosoma mansoni retinoic acid receptor RXR 0.0489 0.0738 0.0738
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0176 0.0176
Brugia malayi SET domain containing protein 0.002 0.001 0.0016
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0008 0.0039
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0024 0.0043
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0013 0.0106
Leishmania major hypothetical protein, conserved 0.0129 0.0179 0.0349
Entamoeba histolytica phosphofructokinase, putative 0.022 0.032 0.2252
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0107 0.0106
Brugia malayi G protein-coupled receptor 0.0029 0.0024 0.0043
Echinococcus granulosus neuropeptide receptor A26 0.0497 0.075 0.1001
Trichomonas vaginalis receptor histidine kinase, putative 0.0034 0.0031 0.0222
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0489 0.0738 0.0986
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0625 0.0949 0.1846
Treponema pallidum heat shock protein 90 0.0134 0.0186 0.1262
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Echinococcus multilocularis mitogen activated protein kinase 3 0.0063 0.0077 0.0099
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.058 0.0879 0.1708
Brugia malayi jmjC domain containing protein 0.02 0.029 0.0561
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0306 0.0454 0.088
Brugia malayi Nuclear hormone receptor-like 1 0.0259 0.038 0.0736
Loa Loa (eye worm) hypothetical protein 0.0259 0.038 0.0737
Brugia malayi kinase, mitochondrial precursor 0.0034 0.0031 0.0058
Echinococcus granulosus fmrfamide receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis FTZ F1 alpha 0.0489 0.0738 0.0986
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0034 0.0031 0.0279
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus multilocularis sentrin specific protease 1 0.0047 0.0052 0.0065
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0134 0.0187 0.1318
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Giardia lamblia Histone acetyltransferase GCN5 0.0123 0.017 0.1148
Onchocerca volvulus Protein ultraspiracle homolog 0.0489 0.0738 0.6313
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0043 0.0045 0.0056
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.002 0.0009 0.0015
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0016 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Echinococcus granulosus endoplasmin 0.0134 0.0186 0.0245
Loa Loa (eye worm) hypothetical protein 0.0032 0.0028 0.0051
Echinococcus multilocularis ETS transcription factor Elf 1 0.0043 0.0045 0.0056
Brugia malayi Nuclear hormone receptor-like 1 0.0259 0.038 0.0736
Echinococcus granulosus tyrosine protein kinase Lyn 0.0024 0.0015 0.0017
Mycobacterium tuberculosis Conserved protein 0.01 0.0134 0.1349
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0073 0.0073
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.032 0.062
Trichomonas vaginalis chromobox protein, putative 0.0072 0.009 0.0636
Leishmania major hypothetical protein, conserved 0.002 0.0009 0.0018
Echinococcus granulosus expressed protein 0.0036 0.0034 0.0042
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0022 0.0013 0.0013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0024 0.0023
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0024 0.0028
Plasmodium vivax endoplasmin, putative 0.0168 0.0239 0.2509
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0134 0.0186 0.0361
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0176 0.0176
Loa Loa (eye worm) G protein alpha subunit 3 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0013 0.0106
Trypanosoma brucei unspecified product 0.0111 0.0151 0.0294
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0016 0.0003 0.0002
Loa Loa (eye worm) glutaminase 2 0.0579 0.0877 0.1704
Onchocerca volvulus Bile acid receptor homolog 0.0489 0.0738 0.6313
Schistosoma mansoni hypothetical protein 0.0353 0.0527 0.0526
Brugia malayi TAR-binding protein 0.0127 0.0176 0.034
Schistosoma mansoni jumonji domain containing protein 0.0159 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0029
Plasmodium falciparum DNA repair protein REV1, putative 0.005 0.0056 0.056
Echinococcus multilocularis roundabout 2 0.0017 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0008 0.0054
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0013 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0034 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0013 0.0102
Schistosoma mansoni pyruvate dehydrogenase 0.0034 0.0031 0.0031
Echinococcus granulosus hypothetical protein 0.0029 0.0024 0.0028
Entamoeba histolytica hypothetical protein 0.0027 0.002 0.0141
Entamoeba histolytica hypothetical protein 0.0027 0.002 0.014
Trichomonas vaginalis heat shock protein, putative 0.0168 0.0239 0.1682
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0013 0.0101
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0071 0.0497
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0015
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0009 0.0008
Echinococcus multilocularis GA binding protein alpha chain 0.0294 0.0435 0.0578
Trichomonas vaginalis heat shock protein, putative 0.0103 0.0138 0.0973
Schistosoma mansoni hypothetical protein 0.0043 0.0045 0.0044
Onchocerca volvulus 0.0115 0.0156 0.1317
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0273
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.032 0.2252
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0033 0.0064
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.3325 0.5142 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0013 0.0101
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0013 0.0101
Brugia malayi Pre-SET motif family protein 0.0088 0.0115 0.022
Toxoplasma gondii Erv1 / Alr family protein 0.0067 0.0083 0.0841
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Trypanosoma cruzi DNA topoisomerase II, putative 0.0034 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0023
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0008 0.0015
Schistosoma mansoni GTP-binding protein alpha subunit 0.0016 0.0003 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0024 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.003 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0047 0.0052 0.0509
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0036 0.0034 0.0325
Toxoplasma gondii hypothetical protein 0.0019 0.0008 0.0044
Echinococcus multilocularis expressed protein 0.0036 0.0034 0.0042
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0013 0.0011
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0034 0.0031 0.0038
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0009 0.0018
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0034 0.0031 0.0292
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0015
Schistosoma mansoni transient receptor potential channel 0.0128 0.0178 0.0178
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0013 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.01 0.0134 0.0941
Loa Loa (eye worm) hypothetical protein 0.0661 0.1006 0.1954
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0024 0.0028
Loa Loa (eye worm) hepatopoietin HPO2 0.0067 0.0083 0.0158
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0102
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Onchocerca volvulus 0.0019 0.0008 0.0045
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0869 0.1328 0.2582
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0013 0.0102
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0366 0.0547 0.106
Trypanosoma cruzi heat shock protein 85, putative 0.0168 0.0239 0.0465
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0071 0.0446
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0034 0.0031 0.0292
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0019 0.0008 0.0016
Onchocerca volvulus 0.0029 0.0024 0.0178
Schistosoma mansoni metabotropic glutamate receptor 0.0067 0.0082 0.0082
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0091 0.012 0.0119
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0541 0.0818 0.0818
Toxoplasma gondii exonuclease III APE 0.0019 0.0008 0.0039
Trypanosoma brucei chrX additional, unordered contigs 0.005 0.0056 0.0109
Brugia malayi phosphofructokinase 0.022 0.032 0.0619
Loa Loa (eye worm) hypothetical protein 0.0129 0.0179 0.0347
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0016 0.0032
Onchocerca volvulus 0.0231 0.0337 0.2867
Mycobacterium leprae Probable two-component sensor kinase 0.0034 0.0031 0.0279
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0031 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0036
Echinococcus granulosus GA binding protein alpha chain 0.0294 0.0435 0.0578
Loa Loa (eye worm) nuclear receptor NHR-67 0.0231 0.0337 0.0653
Brugia malayi Fli-1 protein 0.0892 0.1363 0.2649
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0024 0.0028
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0022 0.0013 0.0037
Brugia malayi MH1 domain containing protein 0.0044 0.0047 0.0089
Schistosoma mansoni hypothetical protein 0.0661 0.1006 0.1005
Mycobacterium tuberculosis Probable two component sensor kinase 0.0034 0.0031 0.0292
Echinococcus multilocularis microtubule associated protein 2 0.4822 0.7467 1
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0009 0.0008
Brugia malayi Muscleblind-like protein 0.0315 0.0467 0.0906
Echinococcus granulosus tumor protein p63 0.0938 0.1435 0.1919
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0056 0.0109
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0134 0.0186 0.0245
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0115 0.0156 0.0302
Schistosoma mansoni cytochrome P450 0.0023 0.0013 0.0013
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0162 0.0229 0.0303
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0037 0.0037 0.0045
Schistosoma mansoni eyes absent homolog 0.0095 0.0126 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Entamoeba histolytica phosphofructokinase, putative 0.022 0.032 0.2252
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0071 1
Loa Loa (eye worm) hypothetical protein 0.0306 0.0454 0.088
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0034 0.0031 0.0307
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0018 0.0006 0.0012
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0015
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Echinococcus granulosus histone acetyltransferase KAT2B 0.0134 0.0187 0.0247
Trypanosoma brucei DNA polymerase eta, putative 0.0162 0.0229 0.0446
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0134 0.0187 0.1956
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0024 0.0043
Mycobacterium ulcerans putative regultory protein 0.0034 0.0031 0.0307
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0027 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0058 0.0074
Echinococcus granulosus heat shock protein 90 0.0134 0.0186 0.0245
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0034 0.0031 0.0061
Onchocerca volvulus 0.0029 0.0024 0.0178
Loa Loa (eye worm) hypothetical protein 0.0098 0.0131 0.0253
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0009 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0077 0.0542
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.001 0.0009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0162 0.0229 0.0229
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.3325 0.5142 1
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0024 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0013 0.0102
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0024 0.0023
Loa Loa (eye worm) MH2 domain-containing protein 0.065 0.0987 0.1918
Trypanosoma brucei transcription elongation factor s-II, putative 0.0019 0.0008 0.0016
Echinococcus multilocularis short transient receptor potential channel 6 0.0128 0.0178 0.0234
Trypanosoma brucei protein kinase, putative 0.0063 0.0077 0.015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0013 0.0095
Echinococcus multilocularis tumor protein p63 0.0938 0.1435 0.1919
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.009 0.0173
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0008 0.0016
Echinococcus multilocularis smad 0.0044 0.0047 0.0059
Mycobacterium ulcerans aminopeptidase N PepN 0.0024 0.0016 0.0134
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Brugia malayi nuclear receptor NHR-88 0.0489 0.0738 0.1433
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0013 0.0026
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0766 0.1168 1
Brugia malayi G-protein coupled receptor 0.0029 0.0024 0.0043
Brugia malayi hypothetical protein 0.0084 0.0108 0.0207
Schistosoma mansoni ephrin receptor 0.0066 0.0081 0.0081
Onchocerca volvulus 0.0022 0.0013 0.0085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0049 0.0345
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0027 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.01 0.0134 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.3325 0.5142 1
Echinococcus multilocularis Protein son of sevenless 0.0027 0.002 0.0023
Brugia malayi SET domain containing protein 0.0017 0.0005 0.0006
Trichomonas vaginalis sensor histidine kinase, putative 0.0034 0.0031 0.0222
Echinococcus granulosus Protein son of sevenless 0.0027 0.002 0.0023
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0013 0.0101
Onchocerca volvulus 0.0019 0.0007 0.0039
Echinococcus granulosus cpg binding protein 0.0157 0.0222 0.0294
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.3325 0.5142 1
Leishmania major regulatory subunit of protein kinase a-like protein 0.0022 0.0013 0.0025
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0024 0.0028
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0013 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Plasmodium falciparum heat shock protein 90 0.0168 0.0239 0.2515
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0162 0.0229 0.0444
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0116 0.0159 0.021
Schistosoma mansoni dishevelled 0.0037 0.0037 0.0036
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0022 0.0013 0.0099
Brugia malayi G-protein alpha subunit 0.0016 0.0003 0.0002
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0013 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.0661 0.1006 0.1953
Mycobacterium ulcerans glutaminase 0.0579 0.0877 1
Echinococcus multilocularis PWWP domain containing protein 2A 0.0019 0.0008 0.0007
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0022 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.1598 0.246 0.4783
Echinococcus multilocularis segment polarity protein dishevelled 0.0037 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0639 0.097 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0087 0.0087
Schistosoma mansoni high-affinity choline transporter 0.1039 0.1591 0.1591
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0024 0.0028
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0027 0.0027
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0066 0.0081 0.0105
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0625 0.0949 0.1846
Brugia malayi MH2 domain containing protein 0.0044 0.0047 0.0089
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0031 0.0027 0.0026
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0016 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Brugia malayi transcription factor E74 isoform 0.0043 0.0045 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) Smad1 0.0044 0.0047 0.0089
Schistosoma mansoni chromobox protein 0.0072 0.009 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0019 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0013 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0013 0.0106
Onchocerca volvulus 0.0029 0.0024 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0041 0.029
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus multilocularis muscleblind protein 0.0315 0.0467 0.0622
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0071 0.0707
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0009 0.0059
Echinococcus granulosus tachykinin peptides receptor 99D 0.235 0.3628 0.4857
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0009 0.0008
Loa Loa (eye worm) glutamate receptor 0.0031 0.0027 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0013 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0366 0.0547 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0023 0.0161
Brugia malayi jmjC domain containing protein 0.002 0.0009 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0024 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0489 0.0738 0.0986
Echinococcus multilocularis ephrin type A receptor 4 A 0.0066 0.0081 0.0105
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0013 0.0101
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0034 0.0031 0.0246
Loa Loa (eye worm) hypothetical protein 0.0608 0.0923 0.1792
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0042
Echinococcus granulosus cGMP dependent protein kinase 1 0.0036 0.0034 0.0042
Echinococcus granulosus leukotriene A 4 hydrolase 0.0024 0.0016 0.0018
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0034 0.0031 0.0058
Echinococcus granulosus beta LACTamase domain containing family member 0.01 0.0134 0.0175
Echinococcus granulosus segment polarity protein dishevelled 0.0037 0.0037 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0024 0.0043
Loa Loa (eye worm) fli-1 protein 0.0892 0.1363 0.2649
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0071 0.0446
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0027 0.002 0.0146
Brugia malayi PHD-finger family protein 0.0028 0.0023 0.0041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0028
Loa Loa (eye worm) TK/EPH protein kinase 0.0084 0.0108 0.0208
Echinococcus granulosus neuropeptide receptor 0.0029 0.0024 0.0028
Plasmodium vivax hypothetical protein, conserved 0.01 0.0134 0.1382
Giardia lamblia Grp94/Hsp90 0.0134 0.0186 0.1262
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0024 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0013 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.032 0.2252
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0489 0.0738 0.1433
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0024 0.0028
Toxoplasma gondii aminopeptidase N protein 0.0618 0.0938 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Plasmodium falciparum importin beta, putative 0.0033 0.003 0.0276
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0016 0.0003 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0077 0.0542
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0013 0.0013
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0016 0.0003 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0489 0.0738 0.6313
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0489 0.0738 0.0986
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0023
Toxoplasma gondii aminopeptidase n, putative 0.0618 0.0938 1
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0028
Brugia malayi Dopamine receptor protein 1 0.0029 0.0024 0.0043
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0071 1
Echinococcus granulosus Smad4 0.0044 0.0047 0.0059
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0008 0.0012
Onchocerca volvulus Mothers against decapentaplegic homolog 0.002 0.0009 0.0054
Echinococcus multilocularis mitogen activated protein kinase 14 0.3325 0.5142 0.6885
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0016 0.0004 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0024 0.0043
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0618 0.0938 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Onchocerca volvulus 0.0231 0.0337 0.2867
Trypanosoma brucei Aminopeptidase M1, putative 0.0024 0.0016 0.0032
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0073 0.0141
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0067 0.0083 0.0107
Leishmania major DNA polymerase eta, putative 0.005 0.0056 0.0109
Entamoeba histolytica phosphofructokinase, putative 0.022 0.032 0.2252
Brugia malayi photoreceptor-specific nuclear receptor 0.0489 0.0738 0.1433
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0009 0.0055
Echinococcus multilocularis mothers against decapentaplegic 2 0.002 0.0009 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0024 0.0043
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0024 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0024 0.0043
Brugia malayi CHD4 protein 0.002 0.001 0.0016
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.01 0.0134 0.0258
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0073 0.0744
Trypanosoma cruzi cAMP binding protein, putative 0.0022 0.0013 0.0025
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0039 0.0049
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0024 0.0028
Brugia malayi acetyltransferase, GNAT family protein 0.0457 0.0688 0.1336
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0031 0.0287
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0231 0.0337 0.0448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0489 0.0738 0.1434
Mycobacterium tuberculosis Probable conserved lipoprotein 0.01 0.0134 0.1349
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0022 0.0013 0.0094
Schistosoma mansoni hypothetical protein 0.0022 0.0013 0.0013
Echinococcus multilocularis calcium activated potassium channel 0.0023 0.0014 0.0015
Echinococcus multilocularis zinc finger protein 0.002 0.0009 0.0008
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0037 0.0068
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0023
Echinococcus granulosus TRP transient receptor potential channel 0.0073 0.0092 0.012
Brugia malayi hypothetical protein 0.0259 0.038 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0034 0.0031 0.0292
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0022 0.0013 0.0099
Trypanosoma cruzi cAMP response protein 1 0.0022 0.0013 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0151 0.0294
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0034 0.0031 0.0292
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0023
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0013 0.0106
Trypanosoma cruzi Aminopeptidase M1, putative 0.0024 0.0016 0.0032
Echinococcus multilocularis mitogen activated protein kinase 14 0.3325 0.5142 0.6885
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0072 0.0091 0.0174
Echinococcus granulosus mixed lineage leukemia protein mll 0.0042 0.0044 0.0055
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0034 0.0031 0.0292
Brugia malayi polk-prov protein 0.005 0.0056 0.0106
Leishmania major mitochondrial DNA topoisomerase II 0.0034 0.0031 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.01 0.0134 0.1478
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0044 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0271 0.04 0.0532
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0063 0.0077 0.0147
Schistosoma mansoni SET domain protein 0.0072 0.009 0.009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0162 0.0229 0.2338
Leishmania major hypothetical protein, conserved 0.0067 0.0083 0.0161
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.001 0.001
Echinococcus multilocularis expressed conserved protein 0.0036 0.0034 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0013 0.0107
Echinococcus multilocularis bloom syndrome protein 0.0026 0.0019 0.0021
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0022 0.0013 0.0013
Echinococcus granulosus calcium activated potassium channel 0.0023 0.0014 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0625 0.0949 0.6686
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0162 0.0229 0.0444
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0028 0.0021 0.0025
Echinococcus granulosus 6 phosphofructokinase 0.022 0.032 0.0425
Echinococcus multilocularis cd109 antigen 0.002 0.0009 0.0008
Schistosoma mansoni smad1 5 8 and 0.0044 0.0047 0.0047
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0039 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Echinococcus multilocularis ecdysone induced protein 78C 0.0489 0.0738 0.0986
Echinococcus granulosus sodium:glucose cotransporter 2 0.0115 0.0156 0.0206
Brugia malayi cytochrome P450 0.0023 0.0013 0.0023
Echinococcus granulosus mothers against decapentaplegic 6 0.002 0.0009 0.0008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0044 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0013 0.0026
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0034 0.0031 0.0038
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0013 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0489 0.0738 0.0986
Brugia malayi N-terminal motif family protein 0.0766 0.1168 0.2269
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0016 0.0018
Echinococcus granulosus smad 0.0044 0.0047 0.0059
Entamoeba histolytica aminopeptidase, putative 0.0024 0.0016 0.0115
Trichomonas vaginalis set domain proteins, putative 0.066 0.1003 0.7062
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0016 0.0003 0.0003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0489 0.0738 0.1433
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.0093
Echinococcus multilocularis PWWP domain containing protein 2A 0.0019 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0013 0.009
Plasmodium vivax DNA topoisomerase II, putative 0.0034 0.0031 0.0287
Trypanosoma cruzi PAB1-binding protein , putative 0.0129 0.0179 0.0349
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Mycobacterium ulcerans regulatory protein 0.0022 0.0013 0.0093
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0294 0.0435 0.0843
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0034 0.0031 0.0169
Trichomonas vaginalis ras GTP exchange factor, putative 0.0027 0.002 0.014
Brugia malayi follicle stimulating hormone receptor 0.0029 0.0024 0.0043
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0035 0.0033 0.0041
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0027 0.002 0.002
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.022 0.032 0.4583
Schistosoma mansoni dishevelled 0.0037 0.0037 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.4822 0.7467 0.7467
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0031 0.0294
Echinococcus multilocularis titin 0.0019 0.0007 0.0006
Loa Loa (eye worm) heat shock protein 90 0.0168 0.0239 0.0462
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0073 0.0744
Echinococcus granulosus serotonin receptor 0.0029 0.0024 0.0028
Entamoeba histolytica hypothetical protein 0.0072 0.009 0.0633
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0013 0.0024
Echinococcus multilocularis heat shock protein 90 0.0134 0.0186 0.0245
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0058 0.0069 0.0088
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0088 0.0115 0.0115
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0033 0.0311
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Schistosoma mansoni myosin xvIII 0.0029 0.0024 0.0023
Trypanosoma brucei unspecified product 0.0111 0.0151 0.0294
Trypanosoma cruzi aminopeptidase, putative 0.0024 0.0016 0.0032
Schistosoma mansoni nuclear receptor nhr-48 0.0231 0.0337 0.0337
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0013 0.0101
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0024 0.0016 0.0016
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0056 0.0109
Trichomonas vaginalis hypothetical protein 0.0018 0.0006 0.0046
Echinococcus multilocularis son of sevenless 1 0.0027 0.002 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0083 0.0107 0.0106
Echinococcus granulosus high affinity choline transporter 1 0.1039 0.1591 0.2128
Loa Loa (eye worm) RNA binding protein 0.0127 0.0176 0.034
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0031 0.0027 0.0032
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0034 0.0031 0.4065
Schistosoma mansoni steroid hormone receptor ad4bp 0.0489 0.0738 0.0738
Leishmania major heat shock protein, putative 0.0069 0.0085 0.0166
Leishmania major DNA topoisomerase ii 0.0034 0.0031 0.0061
Onchocerca volvulus 0.0137 0.0192 0.162
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0004
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0027 0.0032
Mycobacterium leprae conserved hypothetical protein 0.01 0.0134 0.1804
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0013 0.0106
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0259 0.038 0.038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.002 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0231 0.0337 0.0448
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0031 0.0027 0.0032
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0005 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0366 0.0547 0.0546
Brugia malayi G-protein coupled receptor 0.0029 0.0024 0.0043
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0024 0.0016 0.0016
Schistosoma mansoni transient receptor potential channel 0.0128 0.0178 0.0178
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0016 0.0032
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0027 0.0032
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0625 0.0949 0.1846
Brugia malayi hypothetical protein 0.0024 0.0016 0.0029
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0022 0.0013 0.0087
Brugia malayi Latrophilin receptor protein 2 0.0306 0.0454 0.088
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0058 0.0069 0.0088
Loa Loa (eye worm) hypothetical protein 0.0251 0.0368 0.0714
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Onchocerca volvulus 0.066 0.1003 0.8582
Schistosoma mansoni macroglobulin/complement 0.0021 0.0011 0.0011
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0259 0.038 0.0505
Echinococcus granulosus protein C ets 2 0.0043 0.0045 0.0056
Onchocerca volvulus 0.0022 0.0013 0.0085
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0039 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0039 0.0276
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0016 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0489 0.0738 0.1433
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma brucei developmentally regulated phosphoprotein 0.0034 0.0031 0.0061
Echinococcus granulosus short transient receptor potential channel 6 0.0128 0.0178 0.0234
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0457 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0023
Schistosoma mansoni hypothetical protein 0.0306 0.0454 0.0454
Giardia lamblia Fructose-bisphosphate aldolase 0.0928 0.142 1
Trypanosoma cruzi protein kinase A regulatory subunit 0.0022 0.0013 0.0025
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0489 0.0738 0.0738
Echinococcus granulosus titin 0.0019 0.0007 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.002 0.0009 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0209 0.0303 0.0402
Echinococcus granulosus ras GTP exchange factor 0.0027 0.002 0.0023
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0034 0.0031 0.0061
Echinococcus granulosus ETS domain containing protein Elk 1 0.0043 0.0045 0.0056
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0013 0.0101
Echinococcus multilocularis tachykinin peptides receptor 99D 0.235 0.3628 0.4857
Brugia malayi hypothetical protein 0.0072 0.009 0.0172
Trichomonas vaginalis rotamase, putative 0.0036 0.0034 0.0242
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0013 0.0102
Entamoeba histolytica DNA repair and recombination protein, putative 0.0625 0.0949 0.6686
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0024 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0489 0.0738 0.0986
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0013 0.0101
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0033 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0024 0.0028
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0033 0.0064
Leishmania major DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0027 0.002 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Leishmania major hypothetical protein, conserved 0.0034 0.0031 0.0061
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0016 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0271 0.04 0.04
Echinococcus multilocularis mitogen activated protein kinase 11 0.3325 0.5142 0.6885
Leishmania major cyclic nucleotide-binding protein-like protein 0.0022 0.0013 0.0025
Schistosoma mansoni sodium/solute symporter 0.0115 0.0156 0.0156
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0039 0.0049
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0014 0.0107
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0016 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0023 0.0013 0.0102
Echinococcus multilocularis importin subunit beta 1 0.0033 0.003 0.0036
Mycobacterium leprae putative cytochrome p450 0.0023 0.0013 0.0009
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0013 0.0101
Brugia malayi conserved hypotetical protein 0.0231 0.0337 0.0652
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Echinococcus granulosus microtubule associated protein 2 0.4822 0.7467 1
Schistosoma mansoni histamine h1 receptor 0.0029 0.0024 0.0023
Schistosoma mansoni ran 0.0024 0.0016 0.0016
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0073 0.0092 0.012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma brucei PAB1-binding protein , putative 0.0129 0.0179 0.0349
Echinococcus granulosus histone lysine methyltransferase setb 0.0088 0.0115 0.015
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0034 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni smad1 5 8 and 0.0044 0.0047 0.0047
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0031 0.0027 0.0032
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0013 0.0013
Onchocerca volvulus 0.0024 0.0016 0.0116
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0034 0.0031 0.0292
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0489 0.0738 0.1433
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0034 0.0034
Brugia malayi chromobox protein homolog 3 0.004 0.0041 0.0077
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0036 0.0034 0.0042
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0063 0.0077 0.015
Brugia malayi RNA, U transporter 1 0.0094 0.0124 0.0239
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.032 0.2252
Plasmodium falciparum ataxin-2 like protein, putative 0.0129 0.0179 0.1877
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0037 0.0037 0.0036
Giardia lamblia DNA damage repair protein 0.005 0.0056 0.0344
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0013 0.0101
Brugia malayi nuclear receptor RXR 0.0231 0.0337 0.0652
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0022 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0061 0.0073 0.0073
Loa Loa (eye worm) MH1 domain-containing protein 0.002 0.0009 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.0175 0.0337
Onchocerca volvulus 0.0149 0.0209 0.1771
Echinococcus multilocularis alpha 2 macroglobulin 0.0021 0.0011 0.0011
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.002 0.0141
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0013 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0007 0.0011
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0022 0.0013 0.0025
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0231 0.0337 0.0448
Mycobacterium ulcerans DNA gyrase subunit B 0.0034 0.0031 0.0307
Entamoeba histolytica hypothetical protein 0.0072 0.009 0.0633
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0071 0.0714
Echinococcus multilocularis hepatoma derived growth factor protein 0.0019 0.0008 0.0007
Plasmodium falciparum endoplasmin, putative 0.0103 0.0138 0.1437
Loa Loa (eye worm) hypothetical protein 0.0039 0.0039 0.0074
Echinococcus granulosus sodium:glucose cotransporter 0.0115 0.0156 0.0206
Echinococcus granulosus orexin receptor type 2 0.0029 0.0024 0.0028
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0024 0.0043
Brugia malayi Probable DNA topoisomerase II 0.0034 0.0031 0.0058
Mycobacterium tuberculosis Conserved protein 0.01 0.0134 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0077 0.0077
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0063 0.0077 0.0782
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Brugia malayi Ets-domain containing protein 0.0043 0.0045 0.0084
Echinococcus multilocularis voltage gated potassium channel 0.0035 0.0033 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.0116 0.0159 0.0159
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0115 0.0156 0.0206
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0027 0.002 0.002
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0016 0.0003 0.0002
Echinococcus multilocularis ras GTP exchange factor 0.0027 0.002 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0023
Schistosoma mansoni elf1 0.0043 0.0045 0.0044
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0022 0.0013 0.0013
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.003 0.0276
Brugia malayi Serotonin receptor 0.0029 0.0024 0.0043
Echinococcus multilocularis ets variant gene 4 0.0043 0.0045 0.0056
Brugia malayi Protein kinase domain containing protein 0.0084 0.0109 0.0209
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0031 0.0027 0.0032
Giardia lamblia Heat shock protein HSP 90-alpha 0.0168 0.0239 0.1638
Loa Loa (eye worm) A-macroglobulin complement component family protein 0.0021 0.0011 0.0019
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.002 0.001 0.0018
Brugia malayi MH2 domain containing protein 0.065 0.0987 0.1917
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0039 0.0049
Leishmania major hypothetical protein, conserved 0.0019 0.0008 0.0016
Onchocerca volvulus 0.01 0.0133 0.1119
Mycobacterium tuberculosis Probable esterase LipL 0.01 0.0134 0.1349
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0013 0.0106
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0046 0.037
Echinococcus multilocularis somatostatin receptor 0.0029 0.0024 0.0028
Brugia malayi RasGEF domain containing protein 0.0027 0.002 0.0036
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Brugia malayi PWWP domain containing protein 0.0019 0.0008 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0606 0.0919 0.0919
Onchocerca volvulus 0.0608 0.0923 0.7895
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0039 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.01 0.0134 0.026
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0016 0.0003 0.0003
Echinococcus granulosus zinc finger protein 0.002 0.0009 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0013 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0088 0.0115 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0003
Trichomonas vaginalis ran, putative 0.0024 0.0016 0.0114
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0024 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Loa Loa (eye worm) CXXC zinc finger family protein 0.0149 0.0209 0.0405
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0046 0.0323
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0024 0.0023
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0063 0.0077 0.015
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0037 0.0037 0.0068
Loa Loa (eye worm) TATA binding protein associated factor 0.0024 0.0016 0.0029
Leishmania major DNA polymerase kappa, putative 0.005 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Treponema pallidum catabolite gene activator 0.0022 0.0013 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.003
Schistosoma mansoni transient receptor potential channel 0.0193 0.0278 0.0277
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0489 0.0738 0.0738
Mycobacterium leprae Probable two component sensor kinase MprB 0.0034 0.0031 0.0279
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0066 0.0081 0.0155
Mycobacterium ulcerans DNA polymerase IV 0.0162 0.0229 0.2574
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0231 0.0337 0.0448
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0067 0.0083 0.0161
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0024 0.0178
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0034 0.0031 0.0222
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0058 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0019
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0016 0.0032
Schistosoma mansoni hypothetical protein 0.0126 0.0173 0.0173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0162 0.0229 0.1614
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0016 0.0003 0.0003
Echinococcus multilocularis transient receptor potential ion channel A 0.0184 0.0263 0.0349
Brugia malayi nuclear hormone receptor family member nhr-6 0.0231 0.0337 0.0652
Brugia malayi 6-phosphofructokinase 0.022 0.032 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0034 0.0031 0.0292
Toxoplasma gondii ImpB/MucB/SamB family protein 0.005 0.0056 0.056
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.005 0.0056 0.056
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.142 1
Trypanosoma brucei Flagellar Member 6 0.0022 0.0013 0.0025
Leishmania major ATP-dependent phosphofructokinase 0.022 0.032 0.0622
Trichomonas vaginalis endoplasmin, putative 0.0103 0.0138 0.0973
Toxoplasma gondii Erv1 / Alr family protein 0.0067 0.0083 0.0841
Brugia malayi hypothetical protein 0.0095 0.0126 0.0242
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0027 0.0032
Echinococcus granulosus phd:f box containing protein 0.002 0.0009 0.0008
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0034 0.0031 0.007
Brugia malayi PHD-finger family protein 0.002 0.0009 0.0014
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.004 0.0041 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0231 0.0337 0.0652
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0034 0.0242
Mycobacterium ulcerans hypothetical protein 0.01 0.0134 0.1478
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0013 0.0026
Brugia malayi putative malonyl-CoA decarboxylase 0.2211 0.3412 0.6635
Echinococcus granulosus muscleblind protein 0.0315 0.0467 0.0622
Echinococcus granulosus peregrin 0.0092 0.0121 0.0158
Onchocerca volvulus 0.0037 0.0037 0.0289
Echinococcus multilocularis neuropeptide receptor A26 0.0497 0.075 0.1001
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0016 0.0124
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0024 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0016 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0047 0.0088
Echinococcus granulosus metabotropic glutamate receptor 5 0.0098 0.0131 0.0172
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0018 0.0006 0.0012
Echinococcus granulosus mothers against decapentaplegic 5 0.0044 0.0047 0.0059
Brugia malayi larval opioid receptor 0.0029 0.0024 0.0043
Leishmania major cytochrome p450-like protein 0.0023 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0315 0.0467 0.0906
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0024 0.0028
Echinococcus multilocularis activin receptor type 0.0016 0.0004 0.0002
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus granulosus Nuclear hormone receptor HR96 0.0231 0.0337 0.0448
Echinococcus granulosus bloom syndrome protein 0.0026 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0061 0.0073 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0034 0.0034
Brugia malayi DNA-binding protein D-ETS-3 0.0043 0.0045 0.0084
Echinococcus granulosus patatin phospholipase domain containing protein 0.0022 0.0013 0.0013
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0024 0.0016 0.0125
Trypanosoma cruzi DNA topoisomerase II, putative 0.0034 0.0031 0.0061
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0027 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0007
Loa Loa (eye worm) glutamate receptor 0.008 0.0103 0.0197
Echinococcus multilocularis mothers against decapentaplegic 5 0.0044 0.0047 0.0059
Giardia lamblia Rrm3p helicase 0.0625 0.0949 0.6668
Echinococcus multilocularis serotonin receptor 0.0029 0.0024 0.0028
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0034 0.0031 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0231 0.0337 0.0337
Brugia malayi Cytochrome P450 family protein 0.0023 0.0013 0.0023
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0306 0.0454 0.0454
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0067 0.0082 0.0107
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0069
Brugia malayi hypothetical protein 0.0231 0.0337 0.0652
Plasmodium vivax sentrin-specific protease 1, putative 0.0047 0.0052 0.0503
Mycobacterium tuberculosis Probable hydrolase 0.01 0.0134 0.1349
Schistosoma mansoni ap endonuclease 0.0019 0.0008 0.0007
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.001 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0137 0.0192 0.037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Leishmania major protein kinase, putative 0.0036 0.0034 0.0067
Leishmania major protein kinase A regulatory subunit, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0037 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0013 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0489 0.0738 0.1434
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.002 0.001 0.0018
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0008 0.0046
Schistosoma mansoni hypothetical protein 0.0043 0.0045 0.0044
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.0019 0.0133
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0008 0.0034
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0016 0.0003 0.002
Trypanosoma brucei DNA polymerase IV, putative 0.0162 0.0229 0.0446
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0024 0.0028
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0034 0.0031 0.0307
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0066 0.0081 0.0154
Leishmania major cytochrome p450-like protein 0.0023 0.0013 0.0026
Schistosoma mansoni ran 0.0024 0.0016 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0049 0.0345
Brugia malayi hypothetical protein 0.0259 0.038 0.0736
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0231 0.0337 0.0653
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0231 0.0337 0.2867
Echinococcus multilocularis endoplasmin 0.0134 0.0186 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.01 0.0134 0.0257
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0034 0.0031 0.0222
Echinococcus granulosus ETS transcription factor Elf 2 0.0043 0.0045 0.0056
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma brucei malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0869 0.1328 0.2582
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Mycobacterium ulcerans two component regulator - sensor kinase 0.0034 0.0031 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0023 0.0161
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0069 0.0085 0.06
Echinococcus multilocularis chromobox protein 1 0.0072 0.009 0.0117
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0027 0.005
Trypanosoma brucei aminopeptidase, putative 0.0024 0.0016 0.0032
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0022 0.0026
Trypanosoma cruzi hypothetical protein 0.0027 0.002 0.0039
Echinococcus multilocularis heat shock protein 90 0.0168 0.0239 0.0316
Leishmania major malonyl-coa decarboxylase-like protein 0.0869 0.1328 0.2582
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0024 0.0016 0.0115
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0016 0.0003 0.0002
Echinococcus granulosus nuclear receptor nhr 48 0.0231 0.0337 0.0448
Brugia malayi Transient-receptor-potential like protein 0.0073 0.0092 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0489 0.0738 0.1433
Treponema pallidum fructose-bisphosphate aldolase 0.0928 0.142 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0037 0.0037 0.0289
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0024 0.0016 0.0132
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0022 0.0013 0.0013
Trypanosoma cruzi heat shock protein 90, putative 0.0134 0.0186 0.0361
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0453 0.0683 0.7768
Brugia malayi hypothetical protein 0.0037 0.0037 0.0068
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0013 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Trypanosoma brucei heat shock protein 90, putative 0.0168 0.0239 0.0465
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0259 0.038 0.0505
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0229 0.2338
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0013 0.0026
Echinococcus granulosus tar DNA binding protein 0.0127 0.0176 0.0232
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0073 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni hypothetical protein 0.0019 0.0008 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.01 0.0134 0.0941
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0231 0.0337 0.0448
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.003 0.0058
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0031 0.4065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Mycobacterium tuberculosis Conserved protein 0.0022 0.0013 0.0099
Echinococcus granulosus segment polarity protein dishevelled 0.0037 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0315 0.0467 0.0906
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0022 0.0013 0.0013
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0037 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0024 0.0028
Mycobacterium ulcerans transmembrane transport protein 0.0022 0.0013 0.0093
Leishmania major hypothetical protein, unknown function 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0259 0.038 0.0737
Brugia malayi mothers against decapentaplegic homolog 3 0.002 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0007
Trypanosoma cruzi cAMP response protein 1, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0024
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0022 0.0013 0.0094
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0034 0.0031 0.0307
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0037 0.0045
Trypanosoma cruzi aminopeptidase, putative 0.0024 0.0016 0.0032
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0013 0.0024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0039 0.0073
Brugia malayi Calcitonin receptor-like protein seb-1 0.0968 0.1481 0.2878
Entamoeba histolytica hypothetical protein 0.0019 0.0008 0.0057
Brugia malayi PHD-finger family protein 0.0061 0.0073 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0489 0.0738 0.1434
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0024 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0078 0.015
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Trypanosoma cruzi ISWI complex protein 0.0016 0.0003 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0024 0.0028
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0186 0.1309
Brugia malayi Dopamine receptor protein 2 0.0029 0.0024 0.0043
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0034 0.0031 0.0307
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0366 0.0547 0.0546
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0489 0.0738 0.1433
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0016 0.0003 0.0003
Trichomonas vaginalis esterase, putative 0.01 0.0134 0.0941
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.02 0.029 0.0384
Loa Loa (eye worm) hypothetical protein 0.0034 0.0031 0.0059
Loa Loa (eye worm) MH1 domain-containing protein 0.0044 0.0047 0.0089
Loa Loa (eye worm) cytochrome P450 0.0023 0.0013 0.0024
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0044 0.0055
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0013 0.0011
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.02 0.029 0.0384
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0077 0.0542
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0489 0.0738 0.1433
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0013 0.009
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Echinococcus multilocularis dna polymerase kappa 0.0162 0.0229 0.0303
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0088 0.0115 0.1188
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0069 0.0085 0.0706
Brugia malayi DIX domain containing protein 0.0037 0.0037 0.0068
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0056 0.0109
Echinococcus multilocularis cyclin g associated kinase 0.0084 0.0109 0.0142
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0024 0.0016 0.0115
Entamoeba histolytica heat shock protein 90, putative 0.0168 0.0239 0.1682
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0024 0.0203
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus granulosus heat shock protein 90 0.0168 0.0239 0.0316
Entamoeba histolytica heat shock protein 90, putative 0.0168 0.0239 0.1682
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0016 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0041 0.0329
Echinococcus granulosus ephrin type A receptor 4 A 0.0066 0.0081 0.0105
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0013 0.0101
Loa Loa (eye worm) glutaminase 0.0579 0.0877 0.1704
Loa Loa (eye worm) aminopeptidase N 0.0024 0.0016 0.0029
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0027 0.002 0.0023
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0034 0.0031 0.0292
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0031 0.0294
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0176 0.0232
Echinococcus multilocularis geminin 0.0541 0.0818 0.1092
Brugia malayi Heterochromatin protein 1 0.0072 0.009 0.0173
Brugia malayi Cytochrome P450 family protein 0.0064 0.0078 0.0148
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0013 0.0026
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0353 0.0527 0.1022
Onchocerca volvulus 0.01 0.0134 0.1123
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0022 0.0013 0.0013
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0028
Onchocerca volvulus 0.0017 0.0005 0.0016
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0039 0.0276
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0489 0.0738 0.0738
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0115 0.0156 0.0206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0366 0.0547 0.0546
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0015
Loa Loa (eye worm) endoplasmin 0.0168 0.0239 0.0462
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0037 0.0037 0.0068
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0043 0.0045 0.0084
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0022 0.0026
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0111 0.0145
Schistosoma mansoni protein phosphatase 2C 0.002 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.01 0.0134 0.026
Mycobacterium tuberculosis Probable lipase LipD 0.01 0.0134 0.1349
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0008 0.0032
Schistosoma mansoni hypothetical protein 0.0306 0.0454 0.0454
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0151 0.0294
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.002 0.0141
Brugia malayi Bromodomain containing protein 0.0072 0.0091 0.0174
Loa Loa (eye worm) hypothetical protein 0.0047 0.0052 0.0098
Schistosoma mansoni nuclear receptor 0.0231 0.0337 0.0337
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0008 0.0006
Mycobacterium tuberculosis Possible two component sensor kinase 0.0034 0.0031 0.0292
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0231 0.0337 0.0448
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0022 0.0013 0.0094
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0034 0.0031 0.0058
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0037 0.0045
Brugia malayi DnaJ domain containing protein 0.0126 0.0173 0.0334
Onchocerca volvulus 0.01 0.0134 0.1123
Brugia malayi neuropeptide F receptor 0.0029 0.0024 0.0043
Onchocerca volvulus 0.0027 0.002 0.0146
Brugia malayi GnHR receptor homolog 0.0029 0.0024 0.0043
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0007 0.0007
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0031 0.0294
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0366 0.0547 0.0729
Echinococcus granulosus lysine specific demethylase 5A 0.0083 0.0107 0.0139
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0043 0.0045 0.0084
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0018 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Loa Loa (eye worm) ets-domain-containing protein 0.0043 0.0045 0.0084
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0009 0.0008
Trypanosoma brucei DNA damage repair protein, putative 0.005 0.0056 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Schistosoma mansoni smad 0.0044 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0259 0.038 0.0737
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0024 0.0028
Schistosoma mansoni importin beta-1 0.0033 0.003 0.003
Plasmodium vivax importin-beta 2, putative 0.0033 0.003 0.0269
Loa Loa (eye worm) hypothetical protein 0.0095 0.0126 0.0242
Trypanosoma brucei heat shock protein 84, putative 0.0069 0.0085 0.0166
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0453 0.0683 1
Mycobacterium ulcerans DNA polymerase IV 0.0162 0.0229 0.2574
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0013 0.0095
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1598 0.246 0.4782
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0024 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0013 0.0106
Plasmodium falciparum sentrin-specific protease 1 0.0047 0.0052 0.0509
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0016 0.0032
Brugia malayi Bromodomain containing protein 0.002 0.0009 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0151 0.0294
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0013 0.0026
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0016 0.0032
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0034 0.0031 0.0222
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0063 0.0077 0.015
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0027 0.002 0.014
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0037 0.0036
Echinococcus granulosus ETS transcription factor Elf 2 0.0043 0.0045 0.0056
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0039 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0129 0.0179 0.0349
Mycobacterium ulcerans heat shock protein 90 0.0134 0.0186 0.2076
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0034 0.0031 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0071 0.0714
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0453 0.0683 0.7027
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0473 0.0713 0.0951
Trypanosoma brucei Aminopeptidase M1, putative 0.0024 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni ets-related 0.0043 0.0045 0.0044
Plasmodium vivax JmjC domain containing protein 0.002 0.0009 0.0048
Mycobacterium ulcerans beta-lactamase 0.01 0.0134 0.1478
Loa Loa (eye worm) AGC/PKG protein kinase 0.0036 0.0034 0.0064
Brugia malayi heat shock protein 90 0.0168 0.0239 0.0462
Loa Loa (eye worm) hypothetical protein 0.2211 0.3412 0.6635
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0013 0.0107
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0162 0.0229 0.0446
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0013 0.0106
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0019 0.0008 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Schistosoma mansoni hypothetical protein 0.0072 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0022 0.0013 0.0025
Brugia malayi MH2 domain containing protein 0.002 0.0009 0.0015
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0069 0.0085 0.011
Schistosoma mansoni chromobox protein 0.0072 0.009 0.009
Loa Loa (eye worm) TOPoisomerase family member 0.0034 0.0031 0.0059
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0022 0.0013 0.0099
Leishmania major DNA polymerase eta, putative 0.0162 0.0229 0.0446
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0022 0.0013 0.0094
Echinococcus multilocularis thyroid hormone receptor alpha 0.0606 0.0919 0.1228
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Echinococcus granulosus cGMP dependent protein kinase 1 0.0036 0.0034 0.0042
Brugia malayi F/Y-rich N-terminus family protein 0.0071 0.0088 0.0168
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Schistosoma mansoni ras GTP exchange factor 0.0027 0.002 0.002
Echinococcus multilocularis peregrin 0.0092 0.0121 0.0158
Entamoeba histolytica G protein alpha subunit, putative 0.0016 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0489 0.0738 0.0986
Echinococcus granulosus sodium:myo inositol cotransporter 0.0115 0.0156 0.0206
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0008
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0625 0.0949 0.1846
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0034 0.0031 0.0038
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0015 0.0002 0.0001
Plasmodium falciparum heat shock protein 90, putative 0.0069 0.0085 0.0869
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0034 0.0031 0.007
Schistosoma mansoni survival motor neuron protein 0.0043 0.0045 0.0044
Plasmodium vivax heat shock protein 90, putative 0.0069 0.0085 0.0862
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0023
Plasmodium vivax SET domain protein, putative 0.0088 0.0115 0.1181
Echinococcus granulosus histone acetyltransferase KAT2B 0.0444 0.0668 0.0892
Echinococcus granulosus snurportin 1 0.0353 0.0527 0.0702
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0023
Loa Loa (eye worm) nuclear factor I 0.0024 0.0016 0.003
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0115 0.0156 0.1631
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0024 0.0028
Trichomonas vaginalis DNA polymerase eta, putative 0.0162 0.0229 0.1614
Brugia malayi protein unc-22 0.0019 0.0007 0.0011
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0009 0.0008
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0067 0.0083 0.0161
Schistosoma mansoni RAR-like nuclear receptor 0.0489 0.0738 0.0738
Echinococcus granulosus voltage gated potassium channel 0.0035 0.0033 0.0041
Entamoeba histolytica hypothetical protein 0.0018 0.0006 0.004
Trypanosoma cruzi heat shock protein, putative 0.0069 0.0085 0.0166
Brugia malayi Hsp90 protein 0.0069 0.0085 0.0163
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0022 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0766 0.1168 0.227
Toxoplasma gondii Hsp90 domain-containing protein 0.0069 0.0085 0.0869
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0034 0.0031 0.0307
Brugia malayi nuclear hormone receptor 0.0489 0.0738 0.1433
Loa Loa (eye worm) hypothetical protein 0.0064 0.0077 0.0148
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0034 0.0031 0.007
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0016 0.0018
Echinococcus granulosus allatostatin A receptor 0.0029 0.0024 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0088 0.0115 0.0221
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0489 0.0738 0.0738
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0046 0.0323
Mycobacterium ulcerans two component sensor kinase MprB 0.0034 0.0031 0.0307
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0028
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0936 0.1433 0.1916
Schistosoma mansoni ap endonuclease 0.0019 0.0008 0.0007
Plasmodium falciparum cGMP-dependent protein kinase 0.0036 0.0034 0.0325
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0231 0.0337 0.0337
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0016 0.0032
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0027 0.002 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0088 0.0115 0.0115
Echinococcus granulosus Nuclear hormone receptor HR96 0.0231 0.0337 0.0448
Plasmodium falciparum phd finger protein, putative 0.0061 0.0073 0.0744
Trypanosoma cruzi hypothetical protein, conserved 0.01 0.0134 0.026
Plasmodium falciparum DNA gyrase subunit B 0.0034 0.0031 0.0294
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0186 0.1309
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0176 0.0176
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.01 0.0134 0.1349
Brugia malayi glutaminase DH11.1 0.0579 0.0877 0.1704
Schistosoma mansoni thyroid hormone receptor 0.0606 0.0919 0.0919
Echinococcus granulosus ewsr:fli fusion protein type 0.0043 0.0045 0.0056
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0016 0.0029
Brugia malayi RasGEF domain containing protein 0.0027 0.002 0.0036
Onchocerca volvulus 0.0029 0.0024 0.0178
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0067 0.0083 0.0161
Schistosoma mansoni glutaminase 0.0579 0.0877 0.0877
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.032 0.0476 0.0476
Echinococcus multilocularis protein C ets 2 0.0043 0.0045 0.0056
Brugia malayi hypothetical protein 0.0019 0.0008 0.0013
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0186 0.0361
Loa Loa (eye worm) hypothetical protein 0.0209 0.0303 0.0587
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0024 0.0028
Brugia malayi sulfakinin receptor protein 0.0029 0.0024 0.0043
Onchocerca volvulus 0.0018 0.0006 0.0024
Onchocerca volvulus 0.0029 0.0024 0.0178
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0016 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0073 0.0738
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0034 0.0031 0.0307
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0028
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0009 0.0055
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0176 0.034
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0016 0.0003 0.002
Echinococcus granulosus short transient receptor potential channel 6 0.0128 0.0178 0.0234
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0489 0.0738 0.1434
Brugia malayi hypothetical protein 0.0209 0.0303 0.0586
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0016 0.0004 0.0002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.005 0.0056 0.056
Brugia malayi RE15519p 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Echinococcus granulosus chromobox protein 1 0.0072 0.009 0.0117
Echinococcus granulosus son of sevenless 1 0.0027 0.002 0.0023
Echinococcus multilocularis ETS transcription factor Elf 5 0.0043 0.0045 0.0056
Echinococcus multilocularis 6 phosphofructokinase 0.022 0.032 0.0425
Schistosoma mansoni hepatoma derived growth factor 0.0019 0.0008 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0071 0.0714
Echinococcus granulosus dna polymerase eta 0.0162 0.0229 0.0303
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0013 0.0025
Trypanosoma cruzi heat shock protein 90, putative 0.0099 0.0132 0.0257
Brugia malayi Serotonin receptor 0.0029 0.0024 0.0043
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0023
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0034 0.0031 0.0294
Brugia malayi Dopamine receptor 0.0029 0.0024 0.0043
Schistosoma mansoni nuclear hormone receptor 0.0489 0.0738 0.0738
Trypanosoma brucei ISWI complex protein 0.0016 0.0003 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0131 0.0182 0.0351
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0034 0.0031 0.0061
Toxoplasma gondii histone lysine methyltransferase SET1 0.0298 0.0441 0.468
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0044 0.0047 0.0059
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0016 0.0003 0.002
Leishmania major GTP-binding protein, putative 0.0024 0.0016 0.0032
Brugia malayi Cyclic-nucleotide gated cation channel 0.0031 0.0027 0.005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0126 0.0242
Brugia malayi hypothetical protein 0.0024 0.0016 0.0029
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0039 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0009 0.0018
Trypanosoma brucei protein kinase A regulatory subunit 0.0022 0.0013 0.0025
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.032 0.0622
Loa Loa (eye worm) hypothetical protein 0.0034 0.0031 0.0059
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0058 0.0069 0.0068
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0024 0.0043
Echinococcus multilocularis sex peptide receptor 0.0029 0.0024 0.0028
Loa Loa (eye worm) beta-lactamase 0.01 0.0134 0.0258
Echinococcus granulosus ETS transcription factor Elf 5 0.0043 0.0045 0.0056
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0009
Brugia malayi RNA binding protein 0.0127 0.0176 0.034
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0034 0.0031 0.0222
Entamoeba histolytica Ran family GTPase 0.0024 0.0016 0.0114
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0231 0.0337 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0489 0.0738 0.1433
Brugia malayi CXXC zinc finger family protein 0.0149 0.0209 0.0404
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus multilocularis dnaJ subfamily B 0.1297 0.1993 0.2666
Onchocerca volvulus 0.0489 0.0738 0.6313
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0024 0.0028
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0039 0.0049
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0022 0.0013 0.0013
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0022 0.0013 0.0022
Treponema pallidum cyclic nucleotide binding protein 0.0022 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0024 0.0028
Loa Loa (eye worm) nuclear hormone receptor 0.0231 0.0337 0.0653
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0111 0.0145
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0007
Onchocerca volvulus 0.0029 0.0024 0.0178
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0016 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0176 0.0176
Schistosoma mansoni inositol transporter 0.0115 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0088 0.0115 0.0115
Loa Loa (eye worm) NAK/GAK protein kinase 0.0084 0.0109 0.021
Brugia malayi neuropeptide F receptor 0.0029 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0056 0.0109
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0063 0.0077 0.015
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0027 0.002 0.0023
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0115 0.0156 0.0206
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0009 0.0015
Echinococcus granulosus dnaJ subfamily C 6 0.0126 0.0173 0.0229
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0176 0.034
Schistosoma mansoni bromodomain containing protein 0.002 0.0009 0.0009
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0069 0.0085 0.011
Echinococcus granulosus survival motor neuron protein 1 0.0209 0.0303 0.0402
Onchocerca volvulus 0.0023 0.0013 0.0092
Brugia malayi hypothetical protein 0.0129 0.0179 0.0346
Brugia malayi RasGEF domain containing protein 0.0027 0.002 0.0036
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0023
Schistosoma mansoni DNA polymerase IV / kappa 0.005 0.0056 0.0056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0024 0.0043
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.0019 0.0034
Brugia malayi MH1 domain containing protein 0.0044 0.0047 0.0089
Brugia malayi Ets-domain containing protein 0.0294 0.0435 0.0842
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0098 0.0131 0.0172
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0022 0.0013 0.0025
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0024 0.0043
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0134 0.0186 0.2584
Loa Loa (eye worm) PWWP domain-containing protein 0.0019 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus granulosus sex peptide receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Plasmodium vivax heat shock protein 86, putative 0.0168 0.0239 0.2509
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Echinococcus multilocularis muscleblind protein 1 0.0315 0.0467 0.0622
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0024 0.0028
Echinococcus multilocularis high affinity choline transporter 1 0.1039 0.1591 0.2128
Trypanosoma cruzi hypothetical protein 0.0027 0.002 0.0039
Trichomonas vaginalis receptor histidine kinase, putative 0.0034 0.0031 0.0222
Brugia malayi Nuclear hormone receptor E75 0.0231 0.0337 0.0652
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0008 0.0015
Brugia malayi Endoplasmin precursor 0.0168 0.0239 0.0462
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0071 0.0497
Brugia malayi AF-10 protein 0.002 0.0009 0.0015
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0027 0.002 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0075 0.0075
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0024 0.0028
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0071 0.0714
Brugia malayi hypothetical protein 0.0016 0.0003 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0013 0.0106
Mycobacterium tuberculosis Conserved protein 0.0034 0.0031 0.0292
Trypanosoma brucei DNA polymerase IV, putative 0.0162 0.0229 0.0446
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0016 0.0131
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0006 0.0018
Brugia malayi Augmenter of liver regeneration 0.0067 0.0083 0.0158
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0366 0.0547 0.0729
Trypanosoma cruzi heat shock protein 90, putative 0.0168 0.0239 0.0465
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0019 0.0008 0.0016
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0063 0.0077 0.0147
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0031 0.4065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Brugia malayi hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0013 0.0013
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0023
Trypanosoma brucei unspecified product 0.0162 0.0229 0.0446
Plasmodium falciparum heat shock protein 90, putative 0.0069 0.0085 0.0869
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0231 0.0337 0.2867
Brugia malayi nuclear receptor NHR-67 0.0231 0.0337 0.0652
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0039 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0489 0.0738 0.1433
Echinococcus multilocularis aminopeptidase N 0.0024 0.0016 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0071 0.0497
Schistosoma mansoni hypothetical protein 0.0625 0.0949 0.0949
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0016 0.0032
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Schistosoma mansoni GTP-binding protein alpha subunit 0.0016 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0231 0.0337 0.0337
Echinococcus granulosus transient receptor potential ion channel A 0.0184 0.0263 0.0349
Treponema pallidum catabolite gene activator (Crp) 0.0022 0.0013 0.0037
Echinococcus multilocularis phd:f box containing protein 0.002 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.1297 0.1993 0.1993
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0013 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0013 0.0106
Brugia malayi Smad1 0.0044 0.0047 0.0089
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0625 0.0949 0.1846
Echinococcus multilocularis ETS transcription factor Elf 2 0.0043 0.0045 0.0056
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0022 0.0013 0.0013
Schistosoma mansoni adenoreceptor 0.0029 0.0024 0.0023
Echinococcus granulosus cyclin g associated kinase 0.0084 0.0109 0.0142
Brugia malayi 6-phosphofructokinase 0.022 0.032 0.0619
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0024 0.0016 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.0489 0.0738 0.1433
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0033 0.0064
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0067 0.0083 0.0841
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0034 0.0031 0.0292
Echinococcus multilocularis solute carrier family 5 0.0115 0.0156 0.0206
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0022 0.0013 0.0013
Schistosoma mansoni DNA topoisomerase II 0.0034 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0088 0.0115 0.015
Brugia malayi tailless protein 0.0231 0.0337 0.0652
Echinococcus granulosus neuropeptide s receptor 0.0497 0.075 0.1001
Trichomonas vaginalis helicase, putative 0.0034 0.0031 0.0216
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0063 0.0077 0.015
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0625 0.0949 0.1268
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0489 0.0738 0.0986
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0034 0.0031 0.0292
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0016 0.0003 0.0002
Loa Loa (eye worm) acetyltransferase 0.0457 0.0688 0.1337
Giardia lamblia Kinase, CMGC MAPK 0.0063 0.0077 0.0491
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0271 0.04 0.0532
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0034 0.0031 0.0061
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0034 0.0031 0.0061
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0024 0.0028
Schistosoma mansoni cell adhesion molecule 0.0015 0.0001 0.0001
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0039 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0063 0.0077 0.015
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0116 0.0159 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0056 0.0109
Schistosoma mansoni hypothetical protein 0.0043 0.0045 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0027 0.019
Schistosoma mansoni heat shock protein 0.0069 0.0085 0.0085
Giardia lamblia PHD finger protein 15 0.0061 0.0073 0.0466
Schistosoma mansoni phd/f-box containing protein 0.002 0.0009 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0489 0.0738 0.0986
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0176 0.034
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0162 0.0229 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Echinococcus granulosus PWWP domain containing protein 2A 0.0019 0.0008 0.0007
Toxoplasma gondii heat shock protein 90, putative 0.0168 0.0239 0.2515
Schistosoma mansoni myst-related protein 0.0018 0.0006 0.0005
Onchocerca volvulus 0.0029 0.0024 0.0178
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0028
Plasmodium falciparum histone acetyltransferase GCN5 0.0123 0.017 0.1775
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0016 0.0003 0.0003
Giardia lamblia Heat shock protein HSP 90-alpha 0.0134 0.0186 0.1262
Loa Loa (eye worm) D-ets-2 protein 0.0043 0.0045 0.0084
Brugia malayi nuclear hormone receptor 0.0231 0.0337 0.0652
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0022 0.0013 0.0087
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.3325 0.5142 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0025 0.0175
Trichomonas vaginalis protein kinase inhibitor, putative 0.0126 0.0173 0.1222
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0022 0.0013 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0489 0.0738 0.1434
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0035 0.0033 0.0062
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0489 0.0738 0.0986
Loa Loa (eye worm) DnaJ domain-containing protein 0.0126 0.0173 0.0335
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0022 0.0013 0.009
Schistosoma mansoni inositol transporter 0.0115 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0023 0.0013 0.0013
Echinococcus multilocularis chromobox protein 1 0.0072 0.009 0.0117
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.002 0.001 0.0019
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0133 0.0133
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0028 0.0021 0.0025
Echinococcus multilocularis cpg binding protein 0.0157 0.0222 0.0294
Loa Loa (eye worm) RasGEF domain-containing protein 0.0027 0.002 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0024 0.0028
Entamoeba histolytica DNA topoisomerase II, putative 0.0034 0.0031 0.0222
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0034 0.0031 0.0169
Plasmodium vivax DNA gyrase subunit B, putative 0.0034 0.0031 0.0287
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0013 0.0013
Echinococcus granulosus mothers against decapentaplegic 2 0.002 0.0009 0.0008
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0028
Brugia malayi nuclear receptor NHR-88 0.0231 0.0337 0.0652
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Echinococcus multilocularis ewsr:fli fusion protein type 0.0043 0.0045 0.0056
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0034 0.0064
Brugia malayi putative neuropeptide receptor 0.0029 0.0024 0.0043
Echinococcus granulosus dnaJ subfamily B 0.1297 0.1993 0.2666
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0024 0.0016 0.0018
Echinococcus granulosus mitogen activated protein kinase 0.0063 0.0077 0.0099
Schistosoma mansoni heat shock protein 0.0168 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0019 0.0007 0.0012
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0034 0.0031 0.0292
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0489 0.0738 0.0986
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0008
Schistosoma mansoni endoplasmin 0.0168 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0028
Leishmania major DNA damage repair protein, putative 0.005 0.0056 0.0109
Brugia malayi beta-lactamase family protein 0.01 0.0134 0.0257
Schistosoma mansoni smad 0.002 0.0009 0.0009
Schistosoma mansoni hepatoma derived growth factor 0.0019 0.0008 0.0008
Plasmodium falciparum DNA topoisomerase 2 0.0034 0.0031 0.0294
Schistosoma mansoni bromodomain containing protein 0.002 0.0009 0.0009
Trypanosoma cruzi Flagellar Member 6 0.0022 0.0013 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0457 0.0688 0.0918
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0024 0.0028
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0625 0.0949 0.1268
Brugia malayi N-terminal motif family protein 0.0027 0.002 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0008 0.0016
Leishmania major protein kinase, putative 0.0016 0.0004 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0044 0.0047 0.0089
Schistosoma mansoni metabotropic glutamate receptor 0.0039 0.0039 0.0039
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0013 0.0101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Echinococcus granulosus somatostatin receptor 0.0029 0.0024 0.0028
Mycobacterium tuberculosis Conserved protein 0.01 0.0134 0.1349
Loa Loa (eye worm) latrophilin receptor protein 2 0.0306 0.0454 0.088
Leishmania major developmentally regulated phosphoprotein-like protein 0.0034 0.0031 0.0061
Plasmodium vivax DNA repair protein REV1, putative 0.005 0.0056 0.0553
Brugia malayi P38 map kinase family protein 2 0.3325 0.5142 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0078 0.0149
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0022 0.0013 0.0099
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0013 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0013 0.0106
Schistosoma mansoni 6-phosphofructokinase 0.022 0.032 0.032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0079 0.0102 0.0133
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.001 0.001
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0022 0.0013 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0049 0.0345
Echinococcus granulosus ETS transcription factor Elf 1 0.0043 0.0045 0.0056
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0024 0.0028
Schistosoma mansoni hypothetical protein 0.0019 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0306 0.0454 0.0454
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.0093
Echinococcus granulosus Pleckstrin G protein interacting region 0.0037 0.0037 0.0045
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0063 0.0077 0.015
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0034 0.0031 0.0038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0028
Toxoplasma gondii hypothetical protein 0.0037 0.0037 0.0349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0024 0.0043
Trypanosoma cruzi DNA damage repair protein, putative 0.005 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.0489 0.0738 0.1434
Brugia malayi Cytochrome P450 family protein 0.0023 0.0013 0.0023
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.032 0.0622
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0016 0.0003 0.0003
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0024 0.0028
Trichomonas vaginalis heat shock protein, putative 0.0069 0.0085 0.06
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0013 0.0026
Trypanosoma brucei cAMP response protein 1, putative 0.0022 0.0013 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0033 0.0033
Loa Loa (eye worm) peptidase family M1 containing protein 0.0024 0.0016 0.0029
Brugia malayi Cytochrome P450 family protein 0.0023 0.0013 0.0023
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0489 0.0738 0.0986
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0134 0.0187 0.1961
Schistosoma mansoni phd finger protein 0.003 0.0025 0.0025
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0024 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0473 0.0713 0.0712
Brugia malayi Sodium:solute symporter family protein 0.0115 0.0156 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0013 0.009
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0028
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0005 0.0016
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Plasmodium vivax heat shock protein, putative 0.0069 0.0085 0.0862
Mycobacterium leprae Probable lipase LipE 0.01 0.0134 0.1804
Onchocerca volvulus 0.0019 0.0008 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0489 0.0738 0.1433
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0031 0.0059
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Brugia malayi nuclear receptor RXR 0.0259 0.038 0.0736
Trypanosoma brucei heat shock protein 90, putative 0.0168 0.0239 0.0465
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.0093
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0023
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0009 0.0009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.142 1
Echinococcus multilocularis neuropeptide s receptor 0.0497 0.075 0.1001
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0024 0.0016 0.0032
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0034 0.0031 0.0307
Schistosoma mansoni cellular tumor antigen P53 0.0137 0.0192 0.0191
Schistosoma mansoni jumonji domain containing protein 0.002 0.0009 0.0009
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0618 0.0938 1
Echinococcus granulosus mitogen activated protein kinase 14 0.3325 0.5142 0.6885
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0031 0.0216
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0043 0.0045 0.0084
Onchocerca volvulus 0.0034 0.0032 0.025
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0008 0.0054
Brugia malayi Pre-SET motif family protein 0.058 0.0879 0.1708
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Onchocerca volvulus 0.0024 0.0016 0.0116
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0043 0.0045 0.0044
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0016 0.0003 0.0002
Entamoeba histolytica hypothetical protein 0.0072 0.009 0.0633
Echinococcus granulosus chromobox protein 1 0.0072 0.009 0.0117
Loa Loa (eye worm) RasGEF domain-containing protein 0.0027 0.002 0.0036
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0024 0.0028
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0016 0.0061
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0047 0.0052 0.0051
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0027 0.002 0.014
Echinococcus granulosus c-Jun N-terminal kinases 0.0473 0.0713 0.0951
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0306 0.0454 0.0604
Echinococcus multilocularis serotonin receptor 0.0029 0.0024 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0087 0.0087
Echinococcus multilocularis nuclear receptor nhr 48 0.0231 0.0337 0.0448
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0013 0.0099
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0016 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0162 0.0229 0.0446
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0148
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0024 0.0023
Echinococcus granulosus thyroid hormone receptor alpha 0.0231 0.0337 0.0448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0023
Schistosoma mansoni ets-related 0.0892 0.1363 0.1363
Trypanosoma cruzi heat shock protein 85, putative 0.0168 0.0239 0.0465
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.0162 0.0229 0.0443
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0625 0.0949 0.1846
Echinococcus granulosus aminopeptidase N 0.0024 0.0016 0.0018
Echinococcus granulosus geminin 0.0541 0.0818 0.1092
Plasmodium vivax SET domain containing protein 0.002 0.0009 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0043
Schistosoma mansoni myst-related protein 0.0018 0.0006 0.0005
Echinococcus granulosus importin subunit beta 1 0.0033 0.003 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.01 0.0134 0.026
Onchocerca volvulus 0.0024 0.0016 0.0116
Trypanosoma cruzi Heat shock protein 83, putative 0.0168 0.0239 0.0465
Echinococcus multilocularis transient receptor potential gamma protein 0.0193 0.0278 0.0368
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0034 0.0031 0.0246
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Schistosoma mansoni zinc finger protein 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0231 0.0337 0.0652
Wolbachia endosymbiont of Brugia malayi malonyl-CoA decarboxylase 0.2211 0.3412 1
Trypanosoma brucei protein kinase, putative 0.0016 0.0004 0.0008
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0022 0.0013 0.0013
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0009 0.0008
Brugia malayi ecdysteroid receptor 0.0489 0.0738 0.1433
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0025 0.0175
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0015
Echinococcus granulosus twitchin 0.0025 0.0018 0.002
Onchocerca volvulus 0.0064 0.0077 0.0637
Echinococcus multilocularis mitogen activated protein kinase 11 0.3325 0.5142 0.6885
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0047 0.0052 0.0363
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0034 0.0031 0.0307
Trichomonas vaginalis D-aminoacylase, putative 0.01 0.0134 0.0941
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0022 0.0013 0.0025
Onchocerca volvulus 0.0043 0.0045 0.0359
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0019 0.0133
Schistosoma mansoni endoplasmin 0.0168 0.0239 0.0239
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0042 0.0044 0.0055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0028
Brugia malayi ORL1-like opioid receptor 0.0029 0.0024 0.0043
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0066 0.0081 0.0105
Loa Loa (eye worm) hypothetical protein 0.0231 0.0337 0.0653
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.001 0.0017
Echinococcus granulosus activin receptor type 0.0016 0.0004 0.0002
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0024 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0193 0.0278 0.0538
Leishmania major heat shock protein 83-1 0.0168 0.0239 0.0465
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.01 0.0134 0.1349
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0084
Entamoeba histolytica hypothetical protein 0.0072 0.009 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0013 0.0106
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0022 0.0013 0.0013
Echinococcus multilocularis dnaJ subfamily C 6 0.0126 0.0173 0.0229
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0047 0.0052 0.0051
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0016 0.0003 0.0003
Echinococcus multilocularis GPCR, family 2 0.0306 0.0454 0.0604
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0258
Echinococcus multilocularis snurportin 1 0.0353 0.0527 0.0702
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0069
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0024 0.0023
Toxoplasma gondii heat shock protein HSP90 0.0168 0.0239 0.2515
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0067 0.0083 0.0161
Schistosoma mansoni peptidase 0.002 0.0009 0.0009
Schistosoma mansoni rotamase 0.0036 0.0034 0.0034
Trypanosoma brucei heat shock protein, putative 0.0168 0.0239 0.0465
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0022 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0119 0.0164 0.0316
Loa Loa (eye worm) hypothetical protein 0.005 0.0056 0.0107
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0039 0.0276
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0024 0.0023
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0025
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0016 0.0003 0.002
Trypanosoma cruzi DNA damage repair protein, putative 0.005 0.0056 0.0109
Loa Loa (eye worm) RecQ helicase 0.0026 0.0019 0.0034
Brugia malayi TATA binding protein associated factor 0.0024 0.0016 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0028
Giardia lamblia Pms1-like protein 0.0034 0.0031 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0489 0.0738 0.1433
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0016 0.0003 0.0002
Schistosoma mansoni Smad4 0.002 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0489 0.0738 0.1433
Echinococcus granulosus cd109 antigen 0.002 0.0009 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0057 0.0067 0.047
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0016 0.0018
Echinococcus granulosus hepatoma derived growth factor protein 0.0019 0.0008 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0008 0.0012
Echinococcus multilocularis 0.0023 0.0013 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.142 1
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.032 0.062
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0968 0.1481 0.2879
Toxoplasma gondii LsmAD domain-containing protein 0.0129 0.0179 0.1877
Mycobacterium ulcerans aminopeptidase N PepN 0.0024 0.0016 0.0134
Plasmodium vivax ataxin-2 like protein, putative 0.0129 0.0179 0.1871
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0306 0.0454 0.0604

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 5 uM Inhibitory concentration for human complement component C3 activation relative to compstatin ChEMBL. 15634022
Activity (binding) = 5 uM Inhibitory concentration for human complement component C3 activation relative to compstatin ChEMBL. 15634022
IC50 (binding) = 10.2 uM Inhibitory concentration for human complement component C3 activation ChEMBL. 15634022
IC50 (binding) = 10.2 uM Inhibitory concentration for human complement component C3 activation ChEMBL. 15634022

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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