Detailed information for compound 979306

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 325.367 | Formula: C20H15N5
  • H donors: 1 H acceptors: 3 LogP: 4.87 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(Nc2ccc3c(c2)cc2c(c3)cccc2)n2c(n1)ncn2
  • InChi: 1S/C20H15N5/c1-13-8-19(25-20(23-13)21-12-22-25)24-18-7-6-16-9-14-4-2-3-5-15(14)10-17(16)11-18/h2-12,24H,1H3
  • InChiKey: OXYDLVAOXASTMW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Plasmodium falciparum dihydroorotate dehydrogenase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium yoelii dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_127289 All targets in OG5_127289
Theileria parva dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Neospora caninum dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma brucei gambiense dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Schistosoma mansoni dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Candida albicans likely dihydroorotate oxidase similar to S. pombe ura3 (SPAC57A10.12c) and to S. cerevisiae URA1 (YKL216W) involved in pyrimidin Get druggable targets OG5_127289 All targets in OG5_127289
Leishmania braziliensis dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma cruzi dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Babesia bovis dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD Get druggable targets OG5_127289 All targets in OG5_127289
Plasmodium berghei dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma cruzi dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma congolense dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Leishmania major dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Schistosoma japonicum ko:K00226 dihydroorotate oxidase [EC1.3.3.1], putative Get druggable targets OG5_127289 All targets in OG5_127289
Leishmania mexicana dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Plasmodium falciparum dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_127289 All targets in OG5_127289
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative Get druggable targets OG5_127289 All targets in OG5_127289
Leishmania donovani dihydroorotate dehydrogenase Get druggable targets OG5_127289 All targets in OG5_127289
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative Get druggable targets OG5_127289 All targets in OG5_127289
Candida albicans likely dihydroorotate oxidase similar to S. pombe ura3 (SPAC57A10.12c) and to S. cerevisiae URA1 (YKL216W) involved in pyrimidin Get druggable targets OG5_127289 All targets in OG5_127289
Plasmodium knowlesi dihydroorotate dehydrogenase, putative Get druggable targets OG5_127289 All targets in OG5_127289
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) Get druggable targets OG5_127289 All targets in OG5_127289
Leishmania infantum dihydroorotate dehydrogenase;with=GeneDB:LmjF16.0530 Get druggable targets OG5_127289 All targets in OG5_127289
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_127289 All targets in OG5_127289
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD Get druggable targets OG5_127289 All targets in OG5_127289
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GPCR family 2 0.0047 0.0495 0.0823
Onchocerca volvulus 0.0015 0.008 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0041 0.0047
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0016 0.0088 0.005
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0038 0.0371 0.0573
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0058 0.0156
Echinococcus multilocularis geminin 0.0334 0.4186 0.418
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Brugia malayi Pre-SET motif family protein 0.0432 0.5444 0.8406
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0014 0.0058 0.0048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0074
Trichomonas vaginalis esterase, putative 0.0075 0.085 0.1313
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Onchocerca volvulus 0.0016 0.0088 0.0141
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.048 0.6062 1
Schistosoma mansoni hypothetical protein 0.0043 0.0443 0.1058
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0112 0.0173
Schistosoma mansoni lysyl-tRNA synthetase 0.0028 0.0246 0.0588
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0014 0.0058 0.0081
Onchocerca volvulus 0.0075 0.085 0.1369
Schistosoma mansoni carbonyl reductase 0.0016 0.0088 0.0209
Loa Loa (eye worm) glutathione reductase 0.004 0.04 0.0603
Plasmodium falciparum thioredoxin reductase 0.004 0.04 0.0569
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0062 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0246 0.038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0627
Loa Loa (eye worm) hypothetical protein 0.0237 0.2938 0.4528
Leishmania major trypanothione reductase 0.004 0.04 0.0939
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0088 0.0132
Schistosoma mansoni hypothetical protein 0.0126 0.1509 0.3605
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0246 0.0637
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0013
Entamoeba histolytica hypothetical protein 0.0028 0.0246 0.2097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Schistosoma mansoni hypothetical protein 0.0047 0.0495 0.1182
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0088 0.012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.008 0.0123
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0081 0.0121
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0028 0.0246 0.0785
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.008 0.0123
Plasmodium falciparum dihydroorotate dehydrogenase 0.02 0.2461 0.3614
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0014 0.0058 0.0074
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0072 0.0807 1
Onchocerca volvulus 0.0016 0.0086 0.0139
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0168
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0246 0.0785
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0016 0.0088 0.0125
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0016 0.0088 0.005
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0016 0.0088 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0227 0.0335
Brugia malayi CXXC zinc finger family protein 0.0086 0.0995 0.1536
Leishmania major protein kinase, putative 0.0039 0.0381 0.0889
Schistosoma mansoni carbonyl reductase 0.0016 0.0088 0.0209
Onchocerca volvulus 0.0018 0.0112 0.018
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0407 0.0673
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0014 0.0058 0.0007
Echinococcus granulosus dynamin 1 protein 0.0067 0.0742 0.1243
Echinococcus granulosus neuropeptide s receptor 0.0362 0.4553 0.7709
Echinococcus multilocularis muscleblind protein 1 0.0467 0.5904 0.59
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Brugia malayi lysyl-tRNA synthetase 0.0028 0.0246 0.038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0627
Loa Loa (eye worm) hypothetical protein 0.0027 0.0233 0.0345
Loa Loa (eye worm) thioredoxin reductase 0.004 0.04 0.0603
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0082 0.0937 0.1447
Onchocerca volvulus Slit protein homolog 0.0016 0.009 0.0145
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0081 0.0072
Entamoeba histolytica dynamin-like protein 0.0067 0.0742 0.6583
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0044 0.0452 0.1222
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0201 0.0311
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0041 0.0062
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0246 0.0518
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0014 0.0058 0.0093
Mycobacterium ulcerans short-chain type oxidoreductase 0.0016 0.0088 0.0107
Leishmania major 3-keto-dihydrosphingosine reductase 0.0016 0.0088 0.0082
Echinococcus granulosus neural cadherin 0.0016 0.0086 0.013
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.085 0.1313
Loa Loa (eye worm) hypothetical protein 0.0072 0.0807 0.1233
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0014 0.0058 0.0074
Echinococcus multilocularis neurogenic locus notch protein 4 0.0016 0.0086 0.0077
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0088 0.0237
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0052
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0125
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0366 0.0565
Echinococcus granulosus notch 0.0016 0.0086 0.013
Brugia malayi nuclear receptor NHR-88 0.0012 0.0041 0.0062
Schistosoma mansoni egf-like domain protein 0.0041 0.0416 0.0992
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0016 0.0088 0.005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0024
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0088 0.0082
Trypanosoma brucei trypanothione reductase 0.004 0.04 0.1081
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0246 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0366 0.0775
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0126 0.1509 0.2544
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0246 0.0507
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0018 0.0112 0.0267
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Schistosoma mansoni lysyl-tRNA synthetase 0.0028 0.0246 0.0588
Echinococcus granulosus snurportin 1 0.0302 0.3772 0.6383
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0058 0.0156
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0041 0.0096
Mycobacterium tuberculosis Probable oxidoreductase 0.0102 0.1193 0.189
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0014 0.0058 0.0089
Schistosoma mansoni sugar transporter 0.0018 0.0112 0.0267
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0071 0.0109
Giardia lamblia Short-chain dehydrogenase, putative 0.0016 0.0088 0.0438
Brugia malayi beta-lactamase family protein 0.0075 0.085 0.1313
Brugia malayi MH1 domain containing protein 0.001 0.001 0.0015
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0088 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Schistosoma mansoni dynamin 0.0072 0.0808 0.1931
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0088 0.0151
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0088 0.0209
Echinococcus multilocularis General substrate transporter 0.0108 0.1281 0.1272
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0028 0.0246 0.0636
Schistosoma mansoni DNA helicase recq1 0.0022 0.0163 0.0388
Schistosoma mansoni sugar transporter 0.0018 0.0112 0.0267
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0103 0.1205 0.1848
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0126 0.1509 0.2544
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0088 0.0438
Schistosoma mansoni cell polarity protein 0.0016 0.0086 0.0206
Brugia malayi glutathione reductase 0.004 0.04 0.0617
Loa Loa (eye worm) hypothetical protein 0.0028 0.0248 0.0368
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0039 0.0381 0.1031
Schistosoma mansoni intermediate filament proteins 0.0027 0.0233 0.0556
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0018 0.0112 0.0102
Echinococcus multilocularis protein jagged 1 0.0016 0.0086 0.0077
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.112 0.2918
Plasmodium falciparum hexose transporter 0.0126 0.1509 0.2208
Schistosoma mansoni importin beta-1 0.0028 0.0248 0.0591
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.0055
Giardia lamblia Lysyl-tRNA synthetase 0.0028 0.0246 0.2755
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Brugia malayi hypothetical protein 0.0018 0.0112 0.0173
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0041 0.0062
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.2226 0.3427
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0246 0.0314
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0018 0.0112 0.009
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Schistosoma mansoni sugar transporter 0.0018 0.0112 0.0267
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.1746 0.1738
Brugia malayi Pre-SET motif family protein 0.0064 0.0702 0.1083
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0112 0.0173
Echinococcus multilocularis neurogenic locus notch protein 0.0016 0.0086 0.0077
Schistosoma mansoni protein kinase 0.0039 0.0381 0.091
Onchocerca volvulus 0.0018 0.0112 0.018
Brugia malayi notch-like transmembrane receptor 0.0016 0.0086 0.0133
Echinococcus multilocularis Tolloid protein 1 0.0041 0.0416 0.0406
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0246 0.0637
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0016 0.0088 0.0107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0041 0.0052
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.3772 0.5818
Onchocerca volvulus 0.0016 0.0088 0.0141
Echinococcus multilocularis solute carrier family 22 0.0018 0.0112 0.0102
Schistosoma mansoni hypothetical protein 0.0047 0.0495 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0041 0.0062
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0062 0.0094
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Schistosoma mansoni sugar transporter 0.0018 0.0112 0.0267
Onchocerca volvulus 0.0147 0.1777 0.2862
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Echinococcus multilocularis neurogenic locus protein delta 0.0016 0.0086 0.0077
Echinococcus multilocularis solute carrier family 22 0.0018 0.0112 0.0102
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0016 0.0088 0.005
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0246 0.0637
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.085 0.2299
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.04 0.1081
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0702 0.1676
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.008 0.0123
Onchocerca volvulus 0.0018 0.0112 0.018
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Giardia lamblia Reductase, putative 0.0016 0.0088 0.0438
Onchocerca volvulus 0.0016 0.0088 0.0141
Plasmodium falciparum calcium-dependent protein kinase 1 0.0039 0.0381 0.0542
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0246 0.038
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0856 0.2313
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0416 0.0887
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0041 0.0416 0.0992
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Brugia malayi steroid hormone receptor 0.0012 0.0041 0.0062
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0062 0.0168
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0062 0.0096
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.02 0.2461 0.38
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Trichomonas vaginalis helicase, putative 0.002 0.0135 0.0209
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0246 0.0314
Schistosoma mansoni ran 0.0021 0.0151 0.0361
Echinococcus granulosus importin subunit beta 1 0.0028 0.0248 0.0403
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0246 0.0314
Brugia malayi AMP-binding enzyme family protein 0.0096 0.112 0.1729
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0041 0.0096
Trypanosoma brucei glucose transporter 2A 0.0039 0.0388 0.1048
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0179 0.0276
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0062 0.0062
Trichomonas vaginalis hypothetical protein 0.001 0.0018 0.0028
Onchocerca volvulus Sepiapterin reductase homolog 0.0016 0.0088 0.0141
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0038 0.0371 0.0613
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0026 0.0101
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0452 0.1083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Onchocerca volvulus 0.0044 0.0451 0.0726
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0088 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0058 0.0137
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0151 0.0409
Entamoeba histolytica hypothetical protein 0.0016 0.0088 0.0662
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0443 0.0434
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0018 0.0112 0.0144
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0246 0.0507
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.02 0.2461 1
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Plasmodium vivax dynamin-like protein, putative 0.0067 0.0742 0.1067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0366 0.0989
Leishmania major GTP-binding protein, putative 0.0067 0.0742 0.188
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0168
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0088 0.0151
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.02 0.2461 1
Onchocerca volvulus 0.0016 0.0088 0.0141
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0014 0.0058 0.0089
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Onchocerca volvulus 0.0018 0.0112 0.018
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0248 0.051
Schistosoma mansoni dynamin 0.0072 0.0808 0.1931
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0041 0.0062
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0102 0.1193 0.189
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0088 0.0107
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0014 0.0058 0.0007
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0246 0.3051 0.4986
Onchocerca volvulus 0.0018 0.0112 0.018
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0088 0.0237
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0246 0.038
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0014 0.0058 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Mycobacterium ulcerans sugar transporter 0.0018 0.0112 0.0188
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0088 0.0107
Brugia malayi major facilitator superfamily protein 0.0018 0.0112 0.0173
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0088 0.0237
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0041 0.0052
Schistosoma mansoni protein kinase 0.0039 0.0381 0.091
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0062 0.0013
Schistosoma mansoni septate junction protein 0.0016 0.0086 0.0206
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Entamoeba histolytica hypothetical protein 0.0043 0.0443 0.3877
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0189 0.0179
Onchocerca volvulus 0.0016 0.0086 0.0139
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0315 0.1072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0041 0.0047
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0016 0.0088 0.0082
Schistosoma mansoni hypothetical protein 0.0334 0.4186 1
Brugia malayi hypothetical protein 0.0016 0.0088 0.0135
Toxoplasma gondii EGF family domain-containing protein 0.0016 0.0086 0.0148
Mycobacterium ulcerans dehydrogenase/reductase 0.0016 0.0088 0.0107
Brugia malayi hypothetical protein 0.0237 0.2938 0.4536
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Loa Loa (eye worm) sugar transporter 0.0018 0.0112 0.0158
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0081 0.022
Plasmodium falciparum glutathione reductase 0.0014 0.0062 0.0071
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0189 0.0179
Onchocerca volvulus 0.0018 0.0112 0.018
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0026 0.0061
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0041 0.0065
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0126 0.1509 0.1501
Leishmania major short chain dehydrogenase, putative 0.0016 0.0088 0.0082
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0388 0.1048
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.1061 0.1671
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0088 0.0078
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0058 0.0156
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Echinococcus multilocularis neuropeptide receptor A26 0.0362 0.4553 0.4548
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.0112 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0041 0.0047
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.02 0.2461 0.5476
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0016 0.0088 0.0125
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0111 0.03
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0016 0.0086 0.0139
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0443 0.0685
Loa Loa (eye worm) hypothetical protein 0.0467 0.5904 0.9115
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0537 0.1452
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0082 0.0937 0.1574
Giardia lamblia Hexose transporter 0.0018 0.0112 0.0793
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0256 0.0381
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.085 0.2653
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.085 0.2031
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0041 0.0052
Echinococcus multilocularis oxidoreductase 0.0016 0.0088 0.0078
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0041 0.0062
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.064 0.1529
Mycobacterium ulcerans hypothetical protein 0.0096 0.112 0.3553
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0088 0.0151
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Toxoplasma gondii sugar transporter ST3 0.0018 0.0112 0.0206
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0041 0.0096
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0041 0.0031
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.063
Brugia malayi AMP-binding enzyme family protein 0.0096 0.112 0.1729
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0014 0.0058 0.0089
Plasmodium falciparum dynamin-like protein 0.0067 0.0742 0.1075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0082 0.0937 0.0928
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.042 0.1135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0088 0.0078
Trypanosoma brucei glucose transporter 1E 0.0039 0.0388 0.1048
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0088 0.005
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0039 0.0381 0.0811
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0147 0.1777 0.2733
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0088 0.0135
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Mycobacterium tuberculosis Probable dehydrogenase 0.0016 0.0088 0.005
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus lysyl tRNA synthetase 0.0028 0.0246 0.0401
Onchocerca volvulus 0.0086 0.0995 0.1602
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Giardia lamblia Hypothetical protein 0.0016 0.0088 0.0438
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.02 0.2461 0.4003
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0041 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.085 0.1313
Leishmania major short chain dehydrogenase-like protein 0.0016 0.0088 0.0082
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0024 0.0191 0.0557
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3699 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0088 0.0237
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0041 0.0065
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.085 0.132
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0041 0.0096
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.112 0.442
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0078 0.089 0.1374
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Brugia malayi ecdysteroid receptor 0.0012 0.0041 0.0062
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Echinococcus granulosus solute carrier family 22 0.0018 0.0112 0.0173
Plasmodium falciparum thioredoxin reductase 0.0014 0.0062 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0096 0.112 0.1769
Plasmodium vivax thioredoxin reductase, putative 0.004 0.04 0.0561
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.063
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0246 0.3051 0.5161
Plasmodium vivax CDK-related protein kinase 6, putative 0.0536 0.6784 1
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.3699 1
Onchocerca volvulus 0.0018 0.0112 0.018
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0495 0.075
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0856 0.2313
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0081 0.009
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0086 0.0133
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0014 0.0058 0.0084
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0088 0.0151
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0072 0.0808 0.1235
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0856 0.1242
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0058 0.0137
Brugia malayi aldehyde dehydrogenase 0.0014 0.0058 0.0089
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0163 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0041 0.0047
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Brugia malayi isocitrate dehydrogenase 0.0015 0.0081 0.0125
Onchocerca volvulus 0.0048 0.0506 0.0815
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0125
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0366 0.0604
Toxoplasma gondii transporter, major facilitator family protein 0.0018 0.0112 0.0206
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1689 0.4566
Loa Loa (eye worm) hypothetical protein 0.0038 0.0371 0.0559
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0163 0.0153
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0151 0.0219
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.112 0.3553
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0088 0.0662
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0014 0.0058 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0381 0.091
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Echinococcus multilocularis solute carrier family 22 0.0018 0.0112 0.0102
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0078 0.089 0.1374
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0038 0.0371 0.3226
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0112 0.0303
Plasmodium vivax importin-beta 2, putative 0.0028 0.0248 0.0336
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0096 0.112 0.3553
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Mycobacterium ulcerans lipase LipD 0.0075 0.085 0.2653
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0088 0.005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0052 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0246 0.0314
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.02 0.2461 0.38
Leishmania major glucose transporter, lmgt3 0.0039 0.0388 0.0906
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.063
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0041 0.0062
Brugia malayi MH2 domain containing protein 0.001 0.001 0.0015
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0041 0.0052
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Treponema pallidum prolyl-tRNA synthetase 0.0013 0.0056 0.8189
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0111 0.03
Onchocerca volvulus 0.0016 0.0086 0.0139
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0163 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.008 0.0123
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0163 0.0153
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0082
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0088 0.0107
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0062 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0151 0.137
Echinococcus multilocularis lamin dm0 0.0027 0.0233 0.0223
Brugia malayi EGF-like domain containing protein 0.0016 0.009 0.0139
Mycobacterium ulcerans hypothetical protein 0.0075 0.085 0.2653
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0757 0.1165
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0088 0.0132
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3699 1
Schistosoma mansoni glucose transport protein 0.0126 0.1509 0.3605
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0016 0.0088 0.0237
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0246 0.0366
Loa Loa (eye worm) DRP-1 protein 0.0067 0.0742 0.1133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Schistosoma mansoni smad 0.001 0.001 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0041 0.0062
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0246 0.0637
Leishmania major dihydroorotate dehydrogenase 0.02 0.2461 0.6601
Echinococcus granulosus neuropeptide receptor A26 0.0362 0.4553 0.7709
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0088 0.0132
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.112 0.2918
Entamoeba histolytica hypothetical protein 0.0043 0.0443 0.3877
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0088 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.008 0.0123
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0088 0.0135
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Onchocerca volvulus 0.0064 0.0702 0.113
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0014 0.0058 0.0007
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.2938 0.2931
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0041 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1746 0.4171
Loa Loa (eye worm) oxidoreductase 0.0028 0.0246 0.0366
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0246 0.0637
Onchocerca volvulus Putative transporter 0.0018 0.0112 0.018
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.001 0.0023
Leishmania major protein kinase, putative 0.0018 0.0111 0.0147
Loa Loa (eye worm) sugar transporter 0.0126 0.1509 0.2319
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.008 0.0123
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0041 0.0031
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0026 0.0008
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.085 0.2653
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0078 0.089 0.1374
Onchocerca volvulus 0.0075 0.085 0.1369
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0081 0.0072
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.042 0.1135
Onchocerca volvulus 0.0016 0.0088 0.0141
Brugia malayi hypothetical protein 0.0197 0.2422 0.3741
Brugia malayi MH1 domain containing protein 0.001 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.0807 0.1233
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0041 0.0096
Echinococcus multilocularis synaptic vesicle 2 protein 0.0018 0.0112 0.0102
Onchocerca volvulus 0.0018 0.0112 0.018
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Plasmodium vivax acyl-CoA synthetase, putative 0.0072 0.0807 0.1164
Schistosoma mansoni aldehyde dehydrogenase 0.0246 0.3051 0.729
Schistosoma mansoni laminin gamma-3 chain 0.0016 0.0086 0.0206
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0014 0.0058 0.0048
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0246 0.0588
Schistosoma mansoni hypothetical protein 0.0034 0.0319 0.0763
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Trypanosoma brucei dynamin-1-like protein 0.0067 0.0742 0.2007
Leishmania major GTP-binding protein, putative 0.0021 0.0151 0.0257
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0088 0.0132
Onchocerca volvulus 0.0018 0.0112 0.018
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0041 0.0062
Mycobacterium ulcerans aldehyde dehydrogenase 0.0014 0.0058 0.0007
Schistosoma mansoni cpg binding protein 0.0086 0.0995 0.2376
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0088 0.0151
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0111 0.03
Plasmodium falciparum acyl-CoA synthetase 0.0072 0.0807 0.1171
Mycobacterium ulcerans integral membrane transport protein 0.0018 0.0112 0.0188
Onchocerca volvulus 0.0027 0.0233 0.0375
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Echinococcus granulosus intermediate filament protein 0.0027 0.0233 0.0379
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi Importin beta-1 subunit 0.0028 0.0248 0.0382
Brugia malayi oxidoreductase 0.0016 0.0088 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0016 0.0088 0.005
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0088 0.0141
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0082 0.0937 0.1574
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0246 0.0314
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0018 0.0028
Echinococcus multilocularis neurogenic locus protein delta 0.0016 0.0086 0.0077
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0058 0.0156
Onchocerca volvulus 0.0018 0.0112 0.018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0371 0.0559
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0014 0.0058 0.0081
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0096 0.112 0.3553
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0088 0.0132
Echinococcus multilocularis fibropellin Ia 0.0016 0.0086 0.0077
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0807 0.2509
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0108
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.085 0.132
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0246 0.0237
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0256 0.0418
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0856 0.1235
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0014 0.0058 0.0007
Loa Loa (eye worm) hypothetical protein 0.0096 0.112 0.1717
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0757 0.1165
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Leishmania major pteridine reductase 1 0.0016 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.02 0.2461 0.6654
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0081 0.0125
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Plasmodium falciparum lysine--tRNA ligase 0.0028 0.0246 0.0342
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0014 0.0058 0.0007
Trypanosoma cruzi hexose transporter 0.0039 0.0388 0.1048
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0024 0.0191 0.0223
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0088 0.0078
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.0112 0.0173
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0246 0.0366
Entamoeba histolytica hypothetical protein 0.0023 0.0179 0.1485
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0088 0.0132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.0372
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.085 0.1426
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0088 0.0135
Schistosoma mansoni coup transcription factor 0.0012 0.0041 0.0096
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.5444 0.8404
Brugia malayi hypothetical protein 0.0043 0.0443 0.0684
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Trichomonas vaginalis ran, putative 0.0021 0.0151 0.0234
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0319 0.031
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0018 0.0112 0.0303
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0163 0.0439
Echinococcus granulosus neurogenic locus notch protein 0.0016 0.0086 0.013
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0082
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0016 0.0088 0.0237
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Onchocerca volvulus 0.0018 0.0112 0.018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0189 0.0303
Plasmodium falciparum dynamin-like protein 0.0067 0.0742 0.1075
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0078 0.089 0.1374
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0388 0.1048
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Entamoeba histolytica protein kinase, putative 0.0039 0.0381 0.3317
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0246 0.2098
Trypanosoma cruzi sugar transporter, putative 0.0018 0.0112 0.0303
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0151 0.0142
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0062 0.0168
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.008 0.0123
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.112 1
Leishmania major short chain dehydrogenase, putative 0.0016 0.0088 0.0082
Toxoplasma gondii dynamin-related protein DRPA 0.0067 0.0742 0.162
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0088 0.0135
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.0372
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0366 0.0989
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.008 0.0123
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0856 0.1242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0189 0.045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0041 0.0031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0022
Mycobacterium ulcerans oxidoreductase 0.0016 0.0088 0.0107
Echinococcus granulosus lamin 0.0027 0.0233 0.0379
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0062 0.0168
Brugia malayi hypoxia-induced factor 1 0.0182 0.2226 0.3437
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0088 0.0662
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0495 0.0486
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0088 0.0078
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0246 0.0666
Loa Loa (eye worm) major facilitator superfamily transporter 0.0018 0.0112 0.0158
Brugia malayi Aldehyde dehydrogenase protein 4 0.0014 0.0058 0.0089
Mycobacterium leprae conserved hypothetical protein 0.0075 0.085 0.3298
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0052 0.0072
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0014 0.0058 0.0084
Loa Loa (eye worm) Notch2 0.0016 0.0086 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0246 0.038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Echinococcus granulosus synaptic vesicle 2 protein 0.0018 0.0112 0.0173
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0495 0.0823
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0088 0.0078
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0126 0.1509 0.1501
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0041 0.0062
Brugia malayi Calcium binding EGF domain containing protein 0.0041 0.0416 0.0641
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Schistosoma mansoni hypothetical protein 0.0103 0.1205 0.2878
Mycobacterium leprae Possible regulatory protein 0.0015 0.008 0.0093
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Plasmodium vivax sugar transporter, putative 0.0018 0.0112 0.0136
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0246 0.0314
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0088 0.005
Brugia malayi Inositol-1 0.0037 0.0366 0.0565
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.008 0.007
Trichomonas vaginalis set domain proteins, putative 0.0491 0.6209 0.9588
Schistosoma mansoni ran 0.0021 0.0151 0.0361
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0072 0.0171
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Echinococcus granulosus Tolloid protein 1 0.0041 0.0416 0.0688
Trypanosoma cruzi hexose transporter, putative 0.0021 0.0159 0.043
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0041 0.0062
Giardia lamblia High cysteine protein 0.0016 0.0086 0.042
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0038 0.0371 0.0886
Echinococcus multilocularis laminin 0.0041 0.0416 0.0406
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0163 0.0319
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0014 0.0058 0.0156
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0082
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0246 0.0334
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0014 0.0058 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Echinococcus granulosus solute carrier family 22 0.0018 0.0112 0.0173
Echinococcus granulosus solute carrier family 22 0.0018 0.0112 0.0173
Brugia malayi MH2 domain containing protein 0.0144 0.1741 0.2688
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0366 0.0846
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi Smad1 0.001 0.001 0.0015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0366 0.0565
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Brugia malayi hypothetical protein 0.0075 0.0856 0.1321
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.4442 0.6859
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0052 0.0042
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0163 0.0439
Plasmodium falciparum glutathione reductase 0.004 0.04 0.0569
Echinococcus granulosus delta-like protein 1 0.0016 0.0086 0.013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.1061 0.1671
Onchocerca volvulus Putative cubilin 0.0016 0.0086 0.0139
Plasmodium falciparum calcium-dependent protein kinase 5 0.0039 0.0381 0.0542
Mycobacterium ulcerans aldehyde dehydrogenase 0.0246 0.3051 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0246 0.0366
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.008 0.0119
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.02 0.2461 0.8029
Leishmania major hypothetical protein, conserved 0.0018 0.0112 0.0149
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0016 0.0084 0.0114
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0506 0.0782
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0246 0.0666
Onchocerca volvulus 0.0043 0.0443 0.0714
Plasmodium falciparum proline--tRNA ligase 0.0044 0.0452 0.0646
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0016 0.0086 0.0206
Leishmania major hypothetical protein, conserved 0.0075 0.085 0.2177
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0081 0.022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0233 0.0345
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0096 0.112 0.3553
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.085 0.1313
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.085 0.0841
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0088 0.0662
Entamoeba histolytica protein kinase, putative 0.0039 0.0381 0.3317
Toxoplasma gondii protein kinase, putative 0.0357 0.4477 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0081 0.022
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0016 0.0088 0.0237
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0088 0.0237
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0102 0.1193 0.189
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0088 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.4442 0.6859
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0014 0.0058 0.0081
Echinococcus multilocularis calcium dependent protein kinase 0.0036 0.035 0.0341
Echinococcus multilocularis lamin 0.0027 0.0233 0.0223
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Brugia malayi nuclear hormone receptor 0.0012 0.0041 0.0062
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0081 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.008 0.0123
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.1893 0.3057
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0151 0.0409
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0082
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0151 0.0233
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0246 0.0666
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0088 0.01
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0039 0.0381 0.0811
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0126 0.1509 0.1501
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.085 0.132
Leishmania major glucose transporter, lmgt2 0.0039 0.0388 0.0906
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.008 0.0216
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Giardia lamblia Dynamin 0.0067 0.0742 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0246 0.038
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0088 0.0107
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.008 0.0108
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0246 0.3051 0.3045
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0044 0.0452 0.0969
Trichomonas vaginalis glucose transporter, putative 0.0039 0.0388 0.0598
Leishmania major importin beta-1 subunit, putative 0.0023 0.0179 0.0332
Brugia malayi GCC2 and GCC3 family protein 0.0016 0.0086 0.0133
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0088 0.0108
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0039 0.0381 0.0534
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0388 0.0598
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0088 0.0132
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Leishmania major hypothetical protein, conserved 0.0075 0.0856 0.2192
Brugia malayi PAS domain containing protein 0.0059 0.064 0.0988
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0204 0.2511 0.3682
Loa Loa (eye worm) hypothetical protein 0.0064 0.0702 0.107
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0148
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0452 0.1083
Treponema pallidum NADH oxidase 0.0014 0.0062 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Trypanosoma cruzi dynamin-1-like protein 0.0067 0.0742 0.2007
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0039 0.0381 0.0574
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0246 0.038
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.042 0.1135
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0058 0.0391
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0179 0.0276
Loa Loa (eye worm) hypothetical protein 0.0072 0.0807 0.1233
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0082 0.0937 0.0928
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0366 0.0565
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0016 0.0088 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Giardia lamblia Sugar-proton symporter 0.0018 0.0112 0.0793
Plasmodium vivax glutathione reductase, putative 0.004 0.04 0.0561
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0026 0.0012
Brugia malayi Dynamin 0.0072 0.0808 0.1248
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1746 0.4171
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0088 0.0135
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0246 0.0666
Echinococcus granulosus neurogenic locus notch protein 4 0.0016 0.0086 0.013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0151
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0014 0.0058 0.0007
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0088 0.0237
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0088 0.005
Trichomonas vaginalis steroid dehydrogenase, putative 0.0016 0.0088 0.0135
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0088 0.0078
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0081 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0018 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.112 0.2918
Echinococcus granulosus muscleblind protein 0.0467 0.5904 1
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0088 0.0209
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Loa Loa (eye worm) hypothetical protein 0.0096 0.112 0.1717
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0388 0.1048
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0026 0.0069
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0135 0.0209
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0058 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Brugia malayi Muscleblind-like protein 0.0467 0.5904 0.9116
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0041 0.0052
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Schistosoma mansoni myst-related protein 0.001 0.0014 0.0034
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0088 0.0237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.1746 0.2946
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0016 0.0088 0.005
Echinococcus granulosus neurogenic locus notch protein 0.0016 0.0086 0.013
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Plasmodium vivax dynamin protein, putative 0.0067 0.0742 0.1067
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0062 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Loa Loa (eye worm) dehydrogenase 0.0016 0.0088 0.012
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0627
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0189 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0041 0.0062
Echinococcus multilocularis GPCR, family 2 0.0047 0.0495 0.0486
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0126 0.1509 0.2544
Brugia malayi hypothetical protein 0.0018 0.0112 0.0173
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1689 0.448
Plasmodium vivax lysine--tRNA ligase, putative 0.0028 0.0246 0.0334
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0151
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0016 0.0088 0.0135
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0151 0.024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0081 0.0072
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.1817 0.2805
Leishmania major glucose transporter/membrane transporter D2, putative 0.0039 0.0388 0.0906
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.042 0.1135
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0088 0.0237
Schistosoma mansoni inositol monophosphatase 0.0037 0.0366 0.0873
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Mycobacterium leprae Probable lipase LipE 0.0075 0.085 0.3298
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi Delta serrate ligand family protein 0.0016 0.0086 0.0133
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Plasmodium falciparum steroid dehydrogenase, putative 0.0016 0.0088 0.0108
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0014 0.0058 0.0084
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0018 0.0112 0.0188
Leishmania major lysyl-tRNA synthetase, putative 0.0028 0.0246 0.0518
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.02 0.2461 0.3608
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.1746 0.2946
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0088 0.0078
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0163 0.134
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1741 0.2677
Echinococcus multilocularis notch 0.0016 0.0086 0.0077
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0088 0.0662
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0246 0.038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0041 0.0031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0179 0.0276
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0757 0.1165
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0041 0.0052
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Mycobacterium tuberculosis Conserved protein 0.0075 0.085 0.132
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0014 0.0058 0.0007
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.2938 0.4968
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus multilocularis slit 2 protein 0.0016 0.009 0.008
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Brugia malayi Dynamin central region family protein 0.0067 0.0742 0.1146
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0856 0.2313
Onchocerca volvulus 0.0016 0.0086 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0702 0.1676
Toxoplasma gondii facilitative glucose transporter GT1 0.0126 0.1509 0.3341
Schistosoma mansoni aldehyde dehydrogenase 0.0246 0.3051 0.729
Brugia malayi RNA, U transporter 1 0.008 0.0919 0.1419
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0088 0.0078
Entamoeba histolytica acyl-coA synthetase, putative 0.0096 0.112 1
Echinococcus granulosus protein jagged 1 0.0016 0.0086 0.013
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0038 0.0371 0.0886
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0041 0.0047
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0366 0.1282
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0058 0.0391
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0072 0.0807 0.1249
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0088 0.0132
Plasmodium vivax SET domain protein, putative 0.0064 0.0702 0.1007
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.085 0.1313
Echinococcus granulosus slit 2 protein 0.0016 0.009 0.0136
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Entamoeba histolytica dynamin-1-like protein, putative 0.0067 0.0742 0.6583
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.0372
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0388 0.1048
Onchocerca volvulus 0.0028 0.0246 0.0397
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0246 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.1746 0.1738
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0102 0.1193 0.4722
Onchocerca volvulus 0.0016 0.0088 0.0141
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0039 0.0381 0.0534
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0088 0.0082
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0248 0.0669
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0039 0.0381 0.0534
Schistosoma mansoni hypothetical protein 0.0047 0.0495 0.1182
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Echinococcus multilocularis fibrillin 1 0.0041 0.0416 0.0406
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0086 0.0133
Brugia malayi hypothetical protein 0.0016 0.0088 0.0135
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.1746 0.2696
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0016 0.0088 0.0237
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0252 0.0389
Leishmania major myo-inositol/proton symporter (MIT) 0.0018 0.0112 0.0149
Echinococcus multilocularis protein jagged 1 0.0016 0.0086 0.0077
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.008 0.0119
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0246 0.0785
Echinococcus granulosus solute carrier family 22 0.0018 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.112 0.442
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.112 1
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.085 0.1313
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0388 0.1048
Brugia malayi Zinc finger, C2H2 type family protein 0.0078 0.089 0.1374
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0388 0.0598
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0088 0.0237
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0246 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Leishmania major glucose transporter, lmgt1 0.0039 0.0388 0.0906
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0366 0.1035
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0028 0.0246 0.0636
Loa Loa (eye worm) hypothetical protein 0.0031 0.028 0.0417
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0074
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0088 0.0237
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0014 0.0058 0.0007
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0078 0.089 0.2406
Echinococcus multilocularis dynamin 0.0067 0.0742 0.0733
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0512 0.6476 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Toxoplasma gondii sugar transporter ST2 0.0018 0.0112 0.0206
Onchocerca volvulus 0.0096 0.112 0.1804
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0014 0.0058 0.0048
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0014 0.0058 0.0156
Echinococcus granulosus General substrate transporter 0.0108 0.1281 0.2156
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Echinococcus multilocularis dynamin 1 protein 0.0067 0.0742 0.0733
Loa Loa (eye worm) hypothetical protein 0.0028 0.0246 0.0366
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0416 0.0641
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0246 0.0314
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0246 0.0666
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0016 0.0088 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0381 0.0372
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0452 0.1222
Loa Loa (eye worm) major facilitator superfamily transporter 0.0018 0.0112 0.0158
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0407 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Mycobacterium leprae Probable oxidoreductase 0.0016 0.0088 0.0125
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0016 0.0086 0.0133
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0038 0.0371 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0041 0.0062
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0151 0.0194
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0151
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0041 0.0031
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0088 0.0132
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0135 0.0209
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.227 0.5424
Plasmodium vivax proline--tRNA ligase, putative 0.0044 0.0452 0.0638
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0041 0.0096
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0062 0.0168
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0233 0.0359
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0163 0.0219
Entamoeba histolytica Ran family GTPase 0.0021 0.0151 0.1239
Trypanosoma brucei glucose transporter, putative 0.0039 0.0388 0.1048
Schistosoma mansoni cpg binding protein 0.0091 0.1058 0.2528
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0315 0.0429
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0627
Brugia malayi intermediate filament protein 0.0027 0.0233 0.0359
Brugia malayi beta-lactamase family protein 0.0075 0.085 0.1313
Onchocerca volvulus 0.0016 0.0086 0.0139
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0041 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.112 0.3553
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.1061 0.1671
Echinococcus granulosus laminin 0.0041 0.0416 0.0688
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0062 0.0019
Echinococcus multilocularis dynamin 1 0.0072 0.0808 0.0799
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0028 0.0246 0.038
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0062 0.0096
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0126 0.1509 0.2544
Echinococcus granulosus hypothetical protein 0.0016 0.0088 0.0132
Onchocerca volvulus 0.0012 0.0041 0.0065
Brugia malayi Cam kinase protein 1 0.0039 0.0381 0.0588
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0246 0.0637
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0041 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0041 0.0096
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0088 0.0209
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0016 0.0088 0.0125
Toxoplasma gondii dynamin gtpase 0.0044 0.0449 0.0962
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0041 0.0031
Mycobacterium tuberculosis Conserved protein 0.0075 0.085 0.132
Entamoeba histolytica hypothetical protein 0.0043 0.0443 0.3877
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0041 0.0047
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.085 0.132
Trichomonas vaginalis glucose transporter, putative 0.0039 0.0388 0.0598
Loa Loa (eye worm) hypothetical protein 0.0072 0.0807 0.1233
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0014 0.0058 0.0048
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0248 0.0238
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0388 0.0598
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0088 0.0237
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0062 0.0008
Onchocerca volvulus 0.0491 0.6209 1
Trichomonas vaginalis myo-inositol transporter, putative 0.0018 0.0112 0.0173
Plasmodium falciparum protein kinase 6 0.0536 0.6784 1
Schistosoma mansoni inositol monophosphatase 0.0037 0.0366 0.0873
Brugia malayi Thioredoxin reductase 0.004 0.04 0.0617
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.085 0.2299
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0009 0.00000000011515 0.00000000017781
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0163 0.0236
Loa Loa (eye worm) hypothetical protein 0.0016 0.009 0.0124
Toxoplasma gondii dynamin-related protein DRPB 0.0067 0.0742 0.162
Schistosoma mansoni lamin 0.0027 0.0233 0.0556
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0246 0.0666
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0443 0.1295
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0088 0.005
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0058 0.0156
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0014 0.0058 0.0137
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0016 0.0088 0.0209
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0151 0.0409
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0038 0.0371 0.1304
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0014 0.0058 0.0137
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0163 0.0288
Mycobacterium tuberculosis Probable reductase 0.0091 0.1061 0.1671
Onchocerca volvulus 0.0027 0.0233 0.0375
Plasmodium vivax hypothetical protein, conserved 0.0075 0.085 0.1227
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0163 0.0259
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0081 0.0137
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0388 0.1048
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Toxoplasma gondii ABC1 family protein 0.0075 0.085 0.1863
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Leishmania major protein kinase, putative 0.0018 0.0111 0.0147
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.008 0.0123
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0163 0.0251
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.0112 0.0173
Mycobacterium ulcerans hypothetical protein 0.0156 0.1893 0.6133
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0246 0.0637
Schistosoma mansoni slit 0.0016 0.009 0.0214
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Loa Loa (eye worm) RecQ helicase 0.0022 0.0163 0.0236
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0081 0.0194
Echinococcus granulosus protein jagged 2 0.0016 0.0086 0.013
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0038 0.0371 0.0573
Schistosoma mansoni carbonyl reductase 0.0016 0.0088 0.0209
Echinococcus granulosus cpg binding protein 0.0091 0.1058 0.1779
Onchocerca volvulus 0.0018 0.0112 0.018
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0041 0.0052
Schistosoma mansoni cpg binding protein 0.0091 0.1058 0.2528
Onchocerca volvulus 0.0028 0.0246 0.0397
Loa Loa (eye worm) hypothetical protein 0.0041 0.0416 0.0627
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0088 0.0132
Schistosoma mansoni survival motor neuron protein 0.0048 0.0506 0.1209
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0088 0.0237
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0041 0.0031
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0018 0.0112 0.009
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0039 0.0381 0.0574
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.3699 1
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.6476 1
Brugia malayi Sugar transporter family protein 0.0018 0.0112 0.0173
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0088 0.0662
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0041 0.0052
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0151
Onchocerca volvulus Glucosylceramidase homolog 0.0336 0.4209 0.6779
Loa Loa (eye worm) hypothetical protein 0.0072 0.0807 0.1233
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0111 0.03
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0443 0.1058
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0058 0.0137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0047
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0096 0.112 0.1769
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Echinococcus multilocularis solute carrier family 22 0.0018 0.0112 0.0102
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0062 0.0096
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0246 0.0785
Plasmodium falciparum mitogen-activated protein kinase 2 0.0204 0.2511 0.3687
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0062 0.0088
Mycobacterium ulcerans carveol-like dehydrogenase 0.0016 0.0088 0.0107
Schistosoma mansoni lamin 0.0027 0.0233 0.0556
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0058 0.0137
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.1205 0.1861
Loa Loa (eye worm) inositol-1 0.0037 0.0366 0.055
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.02 0.2461 0.6654
Loa Loa (eye worm) hypothetical protein 0.0075 0.085 0.13
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0246 0.0314
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0039 0.0381 0.0811
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0058 0.0391
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0016 0.0088 0.0141
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0856 0.1874
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0058 0.0137
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0062 0.0089
Plasmodium falciparum importin beta, putative 0.0028 0.0248 0.0344
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0246 0.0401
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.02 0.2461 0.6654
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0256 0.0247
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0041 0.0096
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0088 0.0135
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0041 0.0052
Echinococcus granulosus single minded 2 0.0043 0.0443 0.0736
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0366 0.0356
Entamoeba histolytica hypothetical protein 0.0043 0.0443 0.3877
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0016 0.0088 0.005
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0163 0.0251
Echinococcus multilocularis snurportin 1 0.0302 0.3772 0.3766
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0014 0.0058 0.0007
Echinococcus granulosus protein jagged 2 0.0016 0.0086 0.013
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.085 0.132
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0081 0.0111
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0039 0.0381 0.0588
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0082 0.0937 0.8348
Schistosoma mansoni hypothetical protein 0.0014 0.0058 0.0137
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0151 0.0294
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.112 0.3553
Brugia malayi hypothetical protein 0.0049 0.0511 0.0789
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0702 0.0693
Echinococcus granulosus neurogenic locus protein delta 0.0016 0.0086 0.013
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0233 0.0345
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0495 0.0764
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0081 0.0039
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0088 0.0209
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0041 0.0096
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0044 0.0452 0.1222
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0151
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.2018 0.4484
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0088 0.0078
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0495 0.0764
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.085 0.13
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.008 0.0061
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0088 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Loa Loa (eye worm) aldehyde dehydrogenase 0.0014 0.0058 0.0074
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0041 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0016 0.0088 0.0108
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0015 0.0022
Schistosoma mansoni glucose transport protein 0.0126 0.1509 0.3605
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0381 0.0589
Entamoeba histolytica dynamin-1-like protein, putative 0.002 0.0143 0.1162
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0163 0.0319
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0018 0.0112 0.0226
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0416 0.0627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1746 0.4171
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0163 0.0219
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0495 0.0823
Echinococcus granulosus fibropellin Ia 0.0016 0.0086 0.013
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0246 0.0343
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0126 0.1509 0.1501
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0088 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0702 0.0693
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0016 0.0088 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0388 0.0598
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.02 0.2461 0.6654
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Schistosoma mansoni glucose transport protein 0.0126 0.1509 0.3605
Echinococcus multilocularis neurogenic locus notch protein 0.0016 0.0086 0.0077
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0088 0.0662
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0088 0.0107
Trichomonas vaginalis glucose transporter, putative 0.0018 0.0112 0.0173
Brugia malayi MH2 domain containing protein 0.001 0.001 0.0015
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0088 0.0662
Schistosoma mansoni hypothetical protein 0.0302 0.3772 0.9011
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0016 0.0088 0.0135
Schistosoma mansoni hypothetical protein 0.0047 0.0495 0.1182
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0088 0.0107
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0081 0.0099
Toxoplasma gondii aldehyde dehydrogenase 0.0246 0.3051 0.6801
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Schistosoma mansoni myst-related protein 0.001 0.0014 0.0034
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0163 0.0251
Onchocerca volvulus 0.0016 0.0088 0.0141
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0088 0.0078
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0014 0.0058 0.0156
Echinococcus multilocularis neuropeptide s receptor 0.0362 0.4553 0.4548
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0041 0.0096
Treponema pallidum gamma-glutamyl phosphate reductase 0.0014 0.0058 0.8744
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0062 0.0168
Loa Loa (eye worm) beta-lactamase 0.0075 0.085 0.13
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.008 0.0216
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.1061 0.1671
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.1061 0.1671
Loa Loa (eye worm) hypothetical protein 0.0047 0.0495 0.075
Loa Loa (eye worm) hypothetical protein 0.0039 0.0381 0.0574
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0088 0.0078
Leishmania major hypothetical protein, conserved 0.0016 0.0088 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Trypanosoma brucei dynamin-1-like protein 0.0067 0.0742 0.2007
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0038 0.0371 0.0573
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0995 0.1523
Schistosoma mansoni DNA helicase recq5 0.0022 0.0163 0.0388
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0246 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0041 0.0062
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0088 0.0078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0246 0.3051 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0856 0.1308
Plasmodium falciparum calcium-dependent protein kinase 2 0.0039 0.0381 0.0542
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0014 0.0058 0.0156
Echinococcus multilocularis neural cadherin 0.0016 0.0086 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.085 0.1313
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0062 0.0022
Brugia malayi hypothetical protein 0.0018 0.0112 0.0173
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0014 0.0058 0.0048
Plasmodium vivax calcium-dependent protein kinase, putative 0.0039 0.0381 0.0534
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0702 0.1676
Schistosoma mansoni single-minded 0.0059 0.064 0.1529
Onchocerca volvulus 0.0016 0.0088 0.0141
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0246 0.0314
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0416 0.0887
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0163 0.1533
Brugia malayi Muscle positioning protein 4 0.0016 0.0086 0.0133
Onchocerca volvulus Neurogenic locus notch homolog 0.0016 0.0086 0.0139
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative 0.0067 0.0742 0.1146
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0039 0.0381 0.063
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.008 0.0324
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1741 0.2677
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Echinococcus granulosus calcium dependent protein kinase 0.0036 0.035 0.0578
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0179 0.0483
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0041 0.0031
Toxoplasma gondii thioredoxin reductase 0.004 0.04 0.0851
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0702 0.1529
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0088 0.005
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Schistosoma mansoni dihydroorotate dehydrogenase 0.02 0.2461 0.5879
Loa Loa (eye worm) hypothetical protein 0.0467 0.5904 0.9115
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0366 0.0989
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.085 0.2299
Echinococcus multilocularis protein jagged 2 0.0016 0.0086 0.0077
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0319 0.0525
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0062 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Schistosoma mansoni Smad4 0.001 0.001 0.0023
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.1746 0.2685
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0016 0.0088 0.0237
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0246 0.0518
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.1061 0.4175
Brugia malayi Dynamin 0.0072 0.0808 0.1248
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Toxoplasma gondii hypothetical protein 0.0048 0.0499 0.1073
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0081 0.022
Echinococcus granulosus dynamin 1 0.0072 0.0808 0.1355
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0204 0.2511 0.5588
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0016 0.0088 0.0107
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0163 0.0153
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.4209 0.6499
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0246 0.0507
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0082 0.0937 0.1447
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0088 0.0107
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Onchocerca volvulus 0.0018 0.0112 0.018
Plasmodium falciparum protein kinase 7 0.0357 0.4477 0.6592
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.0055
Loa Loa (eye worm) hypothetical protein 0.0096 0.112 0.1717
Schistosoma mansoni hypothetical protein 0.0048 0.0506 0.1209
Onchocerca volvulus 0.0018 0.0112 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.1509 0.2331
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0096 0.112 0.3553
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0016 0.0088 0.005
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0041 0.0416 0.0627
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0088 0.0237
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.0023
Schistosoma mansoni glucose transporter 0.0018 0.0112 0.0267
Brugia malayi AMP-binding enzyme family protein 0.0096 0.112 0.1729
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0196 0.023
Brugia malayi major facilitator superfamily protein 0.0018 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0648 0.1083
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0028 0.0246 0.0666
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0366 0.3178
Echinococcus granulosus bloom syndrome protein 0.0022 0.0163 0.0259
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Toxoplasma gondii lysine-tRNA ligase 0.0028 0.0246 0.0507
Echinococcus multilocularis cpg binding protein 0.0091 0.1058 0.1049
Toxoplasma gondii sugar transporter ST1 0.0018 0.0112 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0135 0.0209
Onchocerca volvulus 0.0075 0.085 0.1369
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0248 0.0669
Schistosoma mansoni hypothetical protein 0.0334 0.4186 1
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0014 0.0058 0.0007
Loa Loa (eye worm) dehydrogenase 0.0016 0.0088 0.012
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0512 0.6476 1
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0016 0.0088 0.0107
Echinococcus multilocularis muscleblind protein 0.0467 0.5904 0.59
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0088 0.0078
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0024 0.0191 0.0223
Echinococcus multilocularis fat cadherin tumor suppressor 0.0016 0.0086 0.0077
Echinococcus multilocularis musashi 0.0027 0.0233 0.0223
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0088 0.0662
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0081 0.0072
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0495 0.0486
Chlamydia trachomatis lysine--tRNA ligase 0.0028 0.0246 0.2536
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0016 0.0088 0.0662
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Echinococcus granulosus geminin 0.0334 0.4186 0.7086
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0071 0.0094
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium ulcerans oxidoreductase 0.0016 0.0088 0.0107
Schistosoma mansoni dynamin 0.0067 0.0742 0.1773
Trichomonas vaginalis sugar transport protein, putative 0.0018 0.0112 0.0173
Onchocerca volvulus 0.0028 0.0246 0.0397
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0041 0.0047
Onchocerca volvulus Arrow homolog 0.0041 0.0416 0.0669
Loa Loa (eye worm) hypothetical protein 0.015 0.1817 0.2794
Brugia malayi Cadherin domain containing protein 0.0016 0.0086 0.0133
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0018 0.0112 0.0188
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0088 0.0082
Echinococcus granulosus hypothetical protein 0.0016 0.0088 0.0132
Onchocerca volvulus 0.0016 0.0088 0.0141
Trichomonas vaginalis mgm1, putative 0.0067 0.0742 0.1146
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0088 0.0151
Trypanosoma cruzi glucose transporter, putative 0.0018 0.0112 0.0303
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0757 0.1165
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0062 0.0071
Brugia malayi beta-lactamase 0.0075 0.085 0.1313
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0041 0.0096
Entamoeba histolytica recQ family helicase, putative 0.0011 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0028 0.0246 0.0366
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0118
Onchocerca volvulus 0.0018 0.0112 0.018
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0088 0.0237
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0151 0.0202
Mycobacterium ulcerans beta-lactamase 0.0075 0.085 0.2653
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0081 0.0137
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.085 0.2031
Giardia lamblia Prolyl-tRNA synthetase 0.0038 0.0371 0.4579
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0088 0.0135
Plasmodium vivax steroid dehydrogenase, putative 0.0016 0.0088 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0088 0.0237
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0088 0.0209
Mycobacterium ulcerans aldehyde dehydrogenase 0.0246 0.3051 1
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.008 0.0123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0135 0.0209
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0014 0.0058 0.0084
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0702 0.1174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0702 0.1676
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0041 0.0047
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0041 0.0416 0.0627
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.085 0.132
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0041 0.0062
Brugia malayi hypothetical protein 0.0147 0.1777 0.2744
Trypanosoma brucei sugar transporter, putative 0.0018 0.0112 0.0303
Echinococcus granulosus lamin dm0 0.0027 0.0233 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0112 0.0173
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0014 0.0058 0.0391
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0062 0.0094
Leishmania major dehydrogenase-like protein 0.0016 0.0088 0.0082
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0015 0.0022
Onchocerca volvulus 0.0016 0.0088 0.0141
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0016 0.0088 0.005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0062 0.0168
Brugia malayi EGF-like domain containing protein 0.0016 0.0086 0.0133
Leishmania major oxidoreductase-like protein 0.0016 0.0088 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0112 0.0173
Plasmodium falciparum calcium-dependent protein kinase 4 0.0039 0.0381 0.0542
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0014 0.0058 0.0081
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0016 0.0088 0.0125
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0028 0.0246 0.0666
Onchocerca volvulus 0.0016 0.0088 0.0141
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0388 0.0598
Mycobacterium ulcerans dehydrogenase 0.0016 0.0088 0.0107
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0443 0.0434
Echinococcus granulosus protein jagged 1 0.0016 0.0086 0.013
Onchocerca volvulus 0.0016 0.0088 0.0141
Loa Loa (eye worm) hypothetical protein 0.0197 0.2422 0.3731
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.085 0.132
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.1817 0.2794
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0246 0.0637
Echinococcus granulosus dynamin 0.0067 0.0742 0.1243
Onchocerca volvulus 0.0018 0.0112 0.018
Brugia malayi Cadherin domain containing protein 0.0016 0.0086 0.0133
Echinococcus granulosus Sugar transporter ERD6 protein 0.0018 0.0112 0.0173
Schistosoma mansoni notch 0.0016 0.0086 0.0206
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0163 0.0251
Echinococcus granulosus oxidoreductase 0.0016 0.0088 0.0132
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0088 0.0132
Echinococcus multilocularis lysyl tRNA synthetase 0.0028 0.0246 0.0237
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0088 0.0107
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1689 0.4566
Loa Loa (eye worm) hypothetical protein 0.0016 0.0088 0.012
Plasmodium falciparum calcium-dependent protein kinase 3 0.0039 0.0381 0.0542
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0246 0.0637
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.008 0.007
Trichomonas vaginalis dynamin, putative 0.0067 0.0742 0.1146
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0058 0.0156
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0062 0.0067
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.04 0.057
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0062 0.0062
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.1817 0.2805
Brugia malayi Sugar transporter family protein 0.0126 0.1509 0.233
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0088 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0088 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0112 0.0173
Schistosoma mansoni protein kinase 0.0039 0.0381 0.091
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0246 0.038
Schistosoma mansoni hypothetical protein 0.0016 0.0086 0.0206
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0088 0.0132
Loa Loa (eye worm) oxidoreductase 0.0016 0.0088 0.012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0246 0.3051 0.8223
Trichomonas vaginalis sugar transporter, putative 0.0018 0.0112 0.0173
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0163 0.0259
Brugia malayi Sugar transporter family protein 0.0018 0.0112 0.0173
Loa Loa (eye worm) notch protein 0.0016 0.0086 0.0118
Mycobacterium tuberculosis Conserved protein 0.0075 0.085 0.132
Plasmodium vivax hexose transporter 0.0126 0.1509 0.2201
Loa Loa (eye worm) hypothetical protein 0.0022 0.0163 0.0236
Brugia malayi Fibulin-1 precursor 0.0041 0.0416 0.0641
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0443 0.0735
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0086 0.0133

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antimalarial activity as reduced parasitaemia against Plasmodium berghei NK65 infected BALB/c mice (Mus musculus) at 100 mg/kg peroral dose at 10x4hrs then 6x6hrs ChEMBL. 19296651
C0 (ADMET) = 1 uM Plasma concentration in Swiss mouse at 50 mg/kg, po administered as single dose for 240 mins ChEMBL. 19296651
Cp (ADMET) = 2 uM Plasma concentration in Swiss mouse at 50 mg/kg, po administered as single dose ChEMBL. 19296651
IC50 (binding) = 0.056 uM Inhibition of Plasmodium falciparum DHODH assessed as reduction of 2,6-dichloroindophenol by stopped flow spectroscopy ChEMBL. 18522386
IC50 (functional) = 0.19 uM Antiplasmodial activity against Plasmodium falciparum 3D7 in erythrocytes as [3H]hypoxanthine uptake ChEMBL. 18522386
IC50 (binding) > 200 uM Inhibition of human DHODH assessed as reduction of 2,6-dichloroindophenol by stopped flow spectroscopy ChEMBL. 18522386

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 18522386

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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