Detailed information for compound 1231026

Basic information

Technical information
  • TDR Targets ID: 1231026
  • Name: 2-[(3R,4R)-1-butyl-4-methyl-2-oxopyrrolidin-3 -yl]-N-(phenylmethyl)acetamide
  • MW: 302.411 | Formula: C18H26N2O2
  • H donors: 1 H acceptors: 2 LogP: 2.25 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN1C[C@@H]([C@H](C1=O)CC(=O)NCc1ccccc1)C
  • InChi: 1S/C18H26N2O2/c1-3-4-10-20-13-14(2)16(18(20)22)11-17(21)19-12-15-8-6-5-7-9-15/h5-9,14,16H,3-4,10-13H2,1-2H3,(H,19,21)/t14-,16+/m0/s1
  • InChiKey: BGHKUBGLRQLZOP-GOEBONIOSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(3R,4R)-1-butyl-4-methyl-2-oxo-pyrrolidin-3-yl]-N-(phenylmethyl)acetamide
  • 2-[(3R,4R)-1-butyl-4-methyl-2-oxo-3-pyrrolidinyl]-N-(phenylmethyl)acetamide
  • N-(benzyl)-2-[(3R,4R)-1-butyl-2-keto-4-methyl-pyrrolidin-3-yl]acetamide
  • 2-[(3R,4R)-1-butyl-4-methyl-2-oxo-pyrrolidin-3-yl]-N-(phenylmethyl)ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis orexin receptor type 2 0.0707 0.2297 0.4697
Brugia malayi Retinol dehydrogenase 12 0.0046 0.0109 0.0195
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0107
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Brugia malayi Serotonin receptor 0.1666 0.547 1
Brugia malayi RNA binding protein 0.019 0.0586 0.1067
Echinococcus granulosus histone lysine methyltransferase setb 0.0104 0.0303 0.0613
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0037 0.0081 0.0209
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0035 0.0024
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0013 0.0017
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0033 0.0058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0076 0.0065
Echinococcus granulosus neuropeptide Y receptor 0.0707 0.2297 0.4697
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Schistosoma mansoni inositol monophosphatase 0.0037 0.0079 0.0162
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Onchocerca volvulus 0.0016 0.0013 0.0045
Echinococcus granulosus serotonin receptor 0.0707 0.2297 0.4697
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0109 0.0323
Loa Loa (eye worm) hypothetical protein 0.0836 0.2726 0.7224
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Schistosoma mansoni inositol monophosphatase 0.0037 0.0079 0.0162
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0029 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0081 0.0157
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0035 0.0024
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0104 0.0303 0.0798
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0013 0.0045
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus multilocularis neuropeptides capa receptor 0.0707 0.2297 0.4697
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0054 0.011
Brugia malayi cytochrome P450 0.0023 0.0035 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.008 0.0164
Echinococcus granulosus fmrfamide receptor 0.0707 0.2297 0.4697
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Mycobacterium ulcerans oxidoreductase 0.0046 0.0109 0.0098
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) TYRA-2 protein 0.0707 0.2297 0.6086
Brugia malayi neuropeptide F receptor 0.0707 0.2297 0.4196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi PXA domain containing protein 0.0037 0.0081 0.0144
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0046 0.0109 0.0473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0013 0.0017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0609 0.1975 0.5232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0011 0.0259
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0046 0.0109 0.2681
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Onchocerca volvulus 0.0019 0.0021 0.0083
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0156
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0033 0.0134
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0035 0.0024
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0155 0.0406
Leishmania major oxidoreductase-like protein 0.0046 0.0109 0.0554
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0077 0.0331
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Onchocerca volvulus 0.0093 0.0267 0.1155
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0035 0.0024
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0046 0.0109 0.0283
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0048 0.079
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0223
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0081 0.0157
Echinococcus granulosus 7TM GPCR rhodopsin 0.0707 0.2297 0.4697
Echinococcus granulosus hypothetical protein 0.0046 0.0109 0.0214
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0707 0.2297 0.4697
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0086 0.0242 0.0636
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0021 0.0972
Echinococcus granulosus dro:myosuppressin receptor 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0037 0.0081 0.0144
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Brugia malayi follicle stimulating hormone receptor 0.1152 0.3772 0.6895
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0109 0.4298
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0493 0.0897
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0305 0.0294
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0025 0.0015
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0305 0.0294
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Brugia malayi Pre-SET motif family protein 0.0087 0.0247 0.0448
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0081 0.0144
Onchocerca volvulus 0.0016 0.0013 0.0045
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0048 0.2418
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0043 0.0119
Mycobacterium ulcerans endonuclease IV 0.0074 0.0205 0.0194
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus multilocularis neuropeptide receptor A26 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0036 0.0076 0.0321
Echinococcus multilocularis regulator of G protein signaling 0.0037 0.0081 0.0157
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0021 0.0097
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Onchocerca volvulus 0.0087 0.0247 0.1068
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0109 0.5064
Brugia malayi Dopamine receptor protein 2 0.0707 0.2297 0.4196
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0044
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0344 0.0333
Echinococcus granulosus hypothetical protein 0.1441 0.4728 0.968
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0205 1
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0046 0.0109 0.0223
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0407 0.1074
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0109 0.5612
Loa Loa (eye worm) G-protein coupled receptor 0.0707 0.2297 0.6086
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0109 0.0214
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0026 0.0062
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0079 0.4041
Echinococcus multilocularis serotonin receptor 0.0836 0.2726 0.5576
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.089 0.4612
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0033 0.0067
Mycobacterium ulcerans beta-lactamase 0.0036 0.0076 0.0065
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0079 0.0341
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0308 0.0978 0.2588
Brugia malayi PHD-finger family protein 0.0029 0.0054 0.0094
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0029 0.099
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0023 0.0038
Onchocerca volvulus 0.0707 0.2297 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0595 0.1926 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0097 0.028 0.1444
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0076 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0035 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Brugia malayi jmjC domain containing protein 0.0094 0.0271 0.0491
Onchocerca volvulus 0.0046 0.0109 0.0464
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0029 0.0916
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0299 0.0947 0.1727
Entamoeba histolytica cysteine protease, putative 0.0016 0.0013 0.0543
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0035 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0029 0.005
Schistosoma mansoni microtubule-associated protein tau 0.0721 0.2345 0.48
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0707 0.2297 0.4196
Echinococcus multilocularis 0.0023 0.0035 0.0062
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.2681
Schistosoma mansoni DNA polymerase eta 0.0022 0.0033 0.0067
Schistosoma mansoni hypothetical protein 0.0023 0.0035 0.0071
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0081 0.0166
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0595 0.1926 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Leishmania major short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0014 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0707 0.2297 0.4697
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0135 0.0267
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0076 0.0135
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.0271 0.0491
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.0271 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0025 0.0757
Onchocerca volvulus 0.0046 0.0109 0.0464
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis neuropeptide FF receptor 2 0.0707 0.2297 0.4697
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0029 0.0136
Toxoplasma gondii hypothetical protein 0.0096 0.0276 0.0836
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.089 0.4612
Leishmania major cytochrome p450-like protein 0.0033 0.0068 0.0341
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0195 0.039
Toxoplasma gondii carbonyl reductase 1, putative 0.0046 0.0109 0.0323
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0046 0.0109 0.0214
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0046 0.0109 0.5064
Schistosoma mansoni ap endonuclease 0.0021 0.0029 0.0059
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0035 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0033 0.0157
Onchocerca volvulus 0.0016 0.0013 0.0045
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0493 0.1301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0023 0.009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Schistosoma mansoni alpha-glucosidase 0.0139 0.0418 0.0856
Onchocerca volvulus 0.0036 0.0076 0.0321
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0037 0.0081 0.0144
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0344 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0323
Onchocerca volvulus 0.0707 0.2297 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0035 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0035 0.0024
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0046 0.0109 0.0195
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0011 0.0038
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0027 0.0108
Leishmania major cytochrome p450-like protein 0.0023 0.0035 0.0168
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0707 0.2297 0.4196
Mycobacterium ulcerans epimerase 0.002 0.0023 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0091 0.0177
Schistosoma mansoni netrin receptor unc5 0.0014 0.0004 0.0009
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) cytochrome P450 0.0023 0.0035 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0076 0.2944
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus granulosus oxidoreductase 0.0046 0.0109 0.0214
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0305 0.0294
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0104 0.0303 0.0613
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus granulosus g-protein coupled receptor 0.0707 0.2297 0.4697
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0029 0.181
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0068 0.0174
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0081 0.0157
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0109 0.0214
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0046 0.0109 0.0098
Brugia malayi dehydrogenases, short chain protein 9 0.0046 0.0109 0.0195
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0035 0.0024
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0079 0.6959
Onchocerca volvulus 0.0707 0.2297 1
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus multilocularis geminin 0.0334 0.1064 0.2172
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0044 0.0077
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0048 0.2418
Brugia malayi RNA recognition motif domain containing protein 0.019 0.0586 0.1067
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0192 0.0394
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trypanosoma brucei unspecified product 0.0022 0.0033 0.0157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.011 0.0217
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0189 0.0178
Loa Loa (eye worm) hypothetical protein 0.0042 0.0098 0.0254
Loa Loa (eye worm) neuropeptide F receptor 0.0707 0.2297 0.6086
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0035 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0407 0.0825
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0109 0.0214
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0021 0.0096
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0046 0.0109 0.0098
Brugia malayi Protein kinase domain containing protein 0.0014 0.0004 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0407 0.074
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0017
Echinococcus multilocularis G-protein coupled receptor, putative 0.0707 0.2297 0.4697
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0077 0.0331
Loa Loa (eye worm) hypothetical protein 0.1021 0.3339 0.885
Leishmania major DNA polymerase eta, putative 0.0022 0.0033 0.0157
Leishmania major mitochondrial DNA polymerase beta 0.0595 0.1926 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0079 0.0341
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Echinococcus multilocularis conserved hypothetical protein 0.0735 0.239 0.4888
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0407 0.0825
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Onchocerca volvulus 0.0016 0.0013 0.0045
Echinococcus multilocularis neuropeptide receptor 0.0707 0.2297 0.4697
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus neuropeptides capa receptor 0.0707 0.2297 0.4697
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0109 0.0554
Schistosoma mansoni eyes absent homolog 0.0086 0.0242 0.0496
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0109 0.0323
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.0271 0.0546
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0035 0.0024
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.011 0.0286
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0013 0.0054
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.2681
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0055
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) RecQ helicase 0.0021 0.0027 0.0065
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0109 0.0214
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0021 0.054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi hypothetical protein 0.0037 0.0081 0.0144
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0081 0.0166
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0033 0.0022
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0129 0.0337
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0077 0.0148
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus peptide allatostatin:somatostatin 0.0707 0.2297 0.4697
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0027 0.0045
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0044 0.0082
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0299 0.0947 0.2505
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0046 0.0109 0.2681
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0013 0.0095
Mycobacterium ulcerans hypothetical protein 0.0313 0.0995 0.0985
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0029 0.007
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0046 0.0109 0.0464
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0013 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0046 0.0109 0.0098
Echinococcus granulosus neuropeptide receptor A26 0.0707 0.2297 0.4697
Echinococcus granulosus dna polymerase eta 0.0022 0.0033 0.0058
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus dna polymerase kappa 0.0022 0.0033 0.0058
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0032 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0084 0.0237 0.0476
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0135
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0011 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0035 0.0024
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000030315
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis neuropeptide Y receptor 0.0707 0.2297 0.4697
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Schistosoma mansoni neuropeptide f receptor 76f 0.0707 0.2297 0.4702
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0189 0.0378
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0204 0.0634 0.1675
Mycobacterium leprae Probable oxidoreductase 0.0046 0.0109 0.2681
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0021 0.0035
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0011 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0048 0.2418
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0076 0.0147
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0021 0.0096
Mycobacterium ulcerans dehydrogenase 0.0046 0.0109 0.0098
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Brugia malayi putative neuropeptide receptor 0.0707 0.2297 0.4196
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0021 0.0096
Echinococcus multilocularis retinol dehydrogenase 13 0.0046 0.0109 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0044 0.009
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.0271 0.0546
Echinococcus granulosus cathepsin l1 0.0016 0.0013 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0016 0.0037
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0153
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Brugia malayi GnHR receptor homolog 0.0707 0.2297 0.4196
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0383
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0079 0.0231
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0046 0.0109 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0707 0.2297 0.4702
Echinococcus multilocularis dna polymerase eta 0.0022 0.0033 0.0058
Echinococcus granulosus sex peptide receptor 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0035 0.0024
Brugia malayi RE15519p 0.0707 0.2297 0.4196
Leishmania major hypothetical protein, conserved 0.0036 0.0076 0.0383
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Brugia malayi Melatonin receptor type 1A 0.0707 0.2297 0.4196
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Echinococcus granulosus alpha 1A adrenergic receptor 0.0707 0.2297 0.4697
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0004
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1021 0.3339 0.6835
Leishmania major trypanothione reductase 0.0046 0.011 0.056
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0087 0.0247 0.0506
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni biogenic amine (5HT) receptor 0.0836 0.2726 0.558
Mycobacterium ulcerans lipase LipD 0.0036 0.0076 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0046 0.0109 0.0464
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0707 0.2297 0.4702
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Giardia lamblia Short-chain dehydrogenase, putative 0.0046 0.0109 1
Echinococcus multilocularis neuropeptide Y receptor 0.0707 0.2297 0.4697
Brugia malayi Cytochrome P450 family protein 0.0033 0.0068 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0344 0.0333
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0046 0.0109 0.2681
Brugia malayi Dopamine receptor protein 1 0.0707 0.2297 0.4196
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0029 0.0018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.3921
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0023 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi neuropeptide F receptor 0.0707 0.2297 0.4196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Brugia malayi Inositol-1 0.0037 0.0079 0.014
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.1021 0.3339 0.885
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus multilocularis somatostatin receptor 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0035 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.0707 0.2297 0.4697
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0029 0.0048
Mycobacterium tuberculosis Probable dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0035 0.0024
Plasmodium falciparum glutathione reductase 0.0046 0.011 0.5127
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0205 0.5664
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0707 0.2297 0.4702
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0081 0.0157
Schistosoma mansoni loxhd1 0.0019 0.0021 0.0044
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0035 0.0062
Onchocerca volvulus 0.0046 0.0109 0.0464
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Schistosoma mansoni amine GPCR 0.0883 0.288 0.5896
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0109 0.0098
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0086 0.0242 0.0636
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Onchocerca volvulus 0.0707 0.2297 1
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Leishmania major pteridine reductase 1 0.0046 0.0109 0.0554
Schistosoma mansoni adenoreceptor 0.0707 0.2297 0.4702
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0032 0.0066
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0081 0.0157
Giardia lamblia DINP protein human, muc B family 0.0022 0.0033 0.2217
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0029 0.0117
Trypanosoma brucei ISWI complex protein 0.0015 0.0008 0.0031
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0021 0.0096
Schistosoma mansoni polycystin 1-related 0.0019 0.0021 0.0044
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Brugia malayi hypothetical protein 0.0016 0.0013 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0021 0.0034
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0021 0.0096
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0032 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1489 0.4885 1
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Schistosoma mansoni hypothetical protein 0.0334 0.1064 0.2179
Echinococcus granulosus neuropeptide s receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0836 0.2726 0.7224
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0121 0.0619
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi putative neuropeptide receptor NPR1 0.0707 0.2297 0.4196
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0004 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0407 0.0825
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Schistosoma mansoni alpha-glucosidase 0.0139 0.0418 0.0856
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Echinococcus granulosus WW domain containing oxidoreductase 0.0046 0.0109 0.0214
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0707 0.2297 0.4702
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.0224
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0029 0.181
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0035 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0435 0.1148
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0076 0.0147
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0707 0.2297 0.4697
Brugia malayi ORL1-like opioid receptor 0.0707 0.2297 0.4196
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0035 0.0024
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0207 0.0423
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0076 0.0195
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0076 0.0065
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0076 0.1656
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0109 1
Echinococcus multilocularis fmrfamide receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0079 0.0153
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0707 0.2297 0.4697
Schistosoma mansoni zinc finger protein 0.0019 0.0022 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0033 0.0067
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0205 0.8234
Trypanosoma brucei glucosidase, putative 0.0036 0.0077 0.0387
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0097 0.028 0.0565
Brugia malayi hypothetical protein 0.0086 0.0242 0.0439
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Brugia malayi PHD-finger family protein 0.0025 0.004 0.0069
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0021 0.0043
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0271 0.0546
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0035 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0025 0.0863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) dehydrogenase 0.0046 0.0109 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0044
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.3921
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0037 0.0081 0.0209
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.0044
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0109 0.0214
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0035 0.0024
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0044
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0025 0.0757
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Echinococcus granulosus biogenic amine 5HT receptor 0.1489 0.4885 1
Echinococcus multilocularis oxidoreductase 0.0046 0.0109 0.0214
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0271 0.0546
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0046 0.0109 0.0214
Brugia malayi hypothetical protein 0.0019 0.0021 0.0035
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0046 0.0109 0.0214
Brugia malayi Cytochrome P450 family protein 0.0023 0.0035 0.0059
Schistosoma mansoni rab6-interacting 0.0019 0.0021 0.0044
Loa Loa (eye worm) fibroinase 0.0016 0.0013 0.0027
Brugia malayi Doublecortin family protein 0.0019 0.0021 0.0035
Loa Loa (eye worm) dehydrogenase 0.0046 0.0109 0.0283
Loa Loa (eye worm) RNA binding protein 0.019 0.0586 0.1547
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0035 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Giardia lamblia Hypothetical protein 0.0046 0.0109 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.019 0.0586 0.1547
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0081 0.0157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.0995 0.0985
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0109 0.0098
Mycobacterium leprae Probable lipase LipE 0.0036 0.0076 0.1656
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0046 0.0109 0.0214
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0035 0.0168
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0044
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0077 0.0136
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0021 0.0689
Loa Loa (eye worm) cysteine protease 0.0016 0.0013 0.0027
Mycobacterium ulcerans hypothetical protein 0.0027 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0299 0.0947 0.2505
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0033 0.0058
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0109 0.5612
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0046 0.0109 0.0214
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Brugia malayi hypothetical protein 0.0046 0.0109 0.0195
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0046 0.0109 0.0214
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0021 0.0034
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0081 0.0166
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0054 0.0136
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0076 0.0065
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0023 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.0209
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Echinococcus multilocularis expressed protein 0.0724 0.2353 0.4812
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0035 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.0209
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0046 0.0109 0.0323
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.0712
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Onchocerca volvulus 0.0707 0.2297 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.005
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0166 0.085
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0035 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0077 0.0197
Echinococcus granulosus G protein coupled receptor 139 0.0707 0.2297 0.4697
Mycobacterium ulcerans hypothetical protein 0.002 0.0023 0.0012
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0109 0.5612
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0014 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0383
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0081 0.0157
Schistosoma mansoni zinc finger protein 0.0015 0.0008 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Toxoplasma gondii exonuclease III APE 0.0021 0.0029 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Toxoplasma gondii ABC1 family protein 0.0036 0.0076 0.0222
Mycobacterium ulcerans short chain dehydrogenase 0.3034 1 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0305 0.0294
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.011 0.4348
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0011 0.0044
Mycobacterium ulcerans oxidoreductase 0.0046 0.0109 0.0098
Echinococcus granulosus neuropeptide receptor 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0205 0.0194
Echinococcus multilocularis neuropeptide receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0021 0.0049
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0033 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0013 0.0019
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0027 0.0046
Entamoeba histolytica hypothetical protein 0.0046 0.0109 0.5612
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0081 0.0144
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus multilocularis G protein coupled receptor 139 0.0707 0.2297 0.4697
Echinococcus multilocularis microtubule associated protein 2 0.0721 0.2345 0.4796
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0033 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus granulosus zinc finger protein 0.0019 0.0022 0.0037
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0046 0.0109 0.0098
Brugia malayi Pre-SET motif family protein 0.0609 0.1975 0.3607
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Schistosoma mansoni hypothetical protein 0.0334 0.1064 0.2179
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0066 0.1356
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0097 0.028 0.0565
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Schistosoma mansoni growth hormone secretagogue receptor 0.0707 0.2297 0.4702
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0076 0.0147
Brugia malayi PXA domain containing protein 0.0037 0.0081 0.0144
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0021 0.0034
Chlamydia trachomatis endonuclease IV 0.0074 0.0205 1
Brugia malayi Thioredoxin reductase 0.0046 0.011 0.0197
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0035 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) glutathione reductase 0.0046 0.011 0.0286
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Brugia malayi sulfakinin receptor protein 0.0707 0.2297 0.4196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0035 0.0024
Onchocerca volvulus 0.0016 0.0013 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0066 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) melatonin receptor type 1A 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0982 0.3209 0.8504
Brugia malayi G-protein coupled receptor 0.0707 0.2297 0.4196
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0037 0.0081 0.0157
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Onchocerca volvulus Neuropeptide F receptor homolog 0.0707 0.2297 1
Giardia lamblia PHD finger protein 15 0.0029 0.0054 0.4361
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0189 0.0378
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus orexin receptor type 2 0.0707 0.2297 0.4697
Echinococcus granulosus tachykinin peptides receptor 99D 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0305 0.0294
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0021 0.0049
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0046 0.0109 0.5612
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1152 0.3772 1
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0046 0.0109 0.0223
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi Bromodomain containing protein 0.0031 0.0061 0.0108
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0295 0.1523
Echinococcus multilocularis sex peptide receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0707 0.2297 0.4697
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0029 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0029 0.0136
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0033 0.0022
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus hypothetical protein 0.0046 0.0109 0.0214
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0189 0.097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0046 0.0109 0.0195
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Schistosoma mansoni hypothetical protein 0.0204 0.0634 0.1298
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni alpha-1 adrenergic receptor 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0707 0.2297 1
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0077 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma brucei unspecified product 0.0016 0.0009 0.0037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0077 0.0331
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0046 0.0109 0.0098
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.164
Echinococcus multilocularis g-protein coupled receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0707 0.2297 0.6086
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0087 0.0247 0.0498
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0387
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0021 0.005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0087 0.0247 0.075
Brugia malayi TAR-binding protein 0.019 0.0586 0.1067
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0076 0.0065
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Echinococcus granulosus 7tm_1 domain containing protein 0.0707 0.2297 0.4697
Trypanosoma brucei unspecified product 0.0016 0.0009 0.0037
Brugia malayi latrophilin 2 splice variant baaae 0.0204 0.0634 0.1155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0033 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0707 0.2297 0.4196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0037 0.0081 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0077 0.0387
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0076 0.0383
Brugia malayi hypothetical protein 0.0026 0.0043 0.0074
Schistosoma mansoni lipoxygenase 0.0053 0.0135 0.0276
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0046 0.0109 0.0473
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0035 0.0024
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0707 0.2297 0.4697
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Schistosoma mansoni cytochrome P450 0.0023 0.0035 0.0071
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Echinococcus granulosus beta-adrenergic receptor kinase 0.0037 0.0081 0.0157
Schistosoma mansoni biogenic amine (5HT) receptor 0.1489 0.4885 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Brugia malayi regulator of G-protein signaling rgs-7 0.0037 0.0081 0.0144
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0109 0.0464
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0021 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0043 0.1567
Schistosoma mansoni rab6-interacting 0.0019 0.0021 0.0044
Loa Loa (eye worm) TAR-binding protein 0.019 0.0586 0.1547
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0205 0.037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Leishmania major hypothetical protein, conserved 0.0026 0.0043 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0344 0.0333
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Onchocerca volvulus 0.0046 0.0109 0.0464
Trypanosoma brucei trypanothione reductase 0.0046 0.011 0.056
Onchocerca volvulus 0.0046 0.0109 0.0464
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Trichomonas vaginalis steroid dehydrogenase, putative 0.0046 0.0109 0.0473
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Leishmania major 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Plasmodium vivax steroid dehydrogenase, putative 0.0046 0.0109 0.4298
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi MH2 domain containing protein 0.0144 0.0435 0.0792
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0037 0.0081 0.0157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Probable reductase 0.0105 0.0305 0.0294
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0046 0.0109 0.0323
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000030315
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Schistosoma mansoni ap endonuclease 0.0021 0.0029 0.0059
Brugia malayi hypothetical protein 0.0046 0.0109 0.0195
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.0271 0.0546
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus multilocularis cysteine protease 0.0016 0.0013 0.0017
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0081 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0154 0.0307
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0097 0.028 0.0508
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0018 0.0392
Echinococcus granulosus biogenic amine 5HT receptor 0.0836 0.2726 0.5576
Brugia malayi oxidoreductase 0.0046 0.0109 0.0195
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0013
Brugia malayi glutathione reductase 0.0046 0.011 0.0197
Schistosoma mansoni retinal dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0707 0.2297 0.6086
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Plasmodium vivax glutathione reductase, putative 0.0046 0.011 0.4348
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0046 0.0109 0.0098
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus multilocularis neuropeptides capa receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0079 0.0341
Brugia malayi Latrophilin receptor protein 2 0.0094 0.0271 0.0491
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Schistosoma mansoni bromodomain containing protein 0.0063 0.0166 0.0339
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0035 0.0024
Mycobacterium ulcerans carveol-like dehydrogenase 0.0046 0.0109 0.0098
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0327
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Brugia malayi beta-lactamase 0.0036 0.0076 0.0135
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus bloom syndrome protein 0.0021 0.0027 0.0046
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0081 0.0144
Echinococcus multilocularis beta adrenergic receptor kinase 0.0037 0.0081 0.0157
Echinococcus multilocularis RUN 0.0019 0.0021 0.0035
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0005
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0013 0.0017
Loa Loa (eye worm) inositol-1 0.0037 0.0079 0.0204
Plasmodium falciparum phd finger protein, putative 0.0029 0.0054 0.2209
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0076 0.0065
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Mycobacterium ulcerans short-chain type oxidoreductase 0.0046 0.0109 0.0098
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0021 0.0052
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0011 0.0044
Onchocerca volvulus 0.0707 0.2297 1
Trichomonas vaginalis set domain proteins, putative 0.0693 0.2253 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Plasmodium falciparum steroid dehydrogenase, putative 0.0046 0.0109 0.5064
Echinococcus multilocularis GPCR, family 2 0.0094 0.0271 0.0546
Leishmania major DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0035 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0054 0.202
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Onchocerca volvulus 0.0016 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) PXA domain-containing protein 0.0037 0.0081 0.0209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0048 0.0037
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0109 0.0554
Trypanosoma brucei oxidoreductase-like protein 0.0046 0.0109 0.0554
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0247 0.0506
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0068 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Onchocerca volvulus 0.0694 0.2254 0.9813
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Onchocerca volvulus 0.0019 0.0021 0.0083
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0046 0.0109 0.0098
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.008 0.0155
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0021 0.0972
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0005 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0035 0.0024
Echinococcus granulosus neuropeptide FF receptor 2 0.0707 0.2297 0.4697
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.011 0.0099
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0154 0.0307
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Toxoplasma gondii thioredoxin reductase 0.0046 0.011 0.0327
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0097 0.028 0.0574
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0029 0.0136
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0021 0.0096
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0011 0.0044
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0189 0.057
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0077 0.0148
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0303 0.0621
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.0271 0.0712
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0013 0.0095
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.008 0.0206
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.008 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0081 0.0166
Echinococcus granulosus Regulator of G protein signaling 20 0.0037 0.0081 0.0157
Echinococcus multilocularis Regulator of G protein signaling 20 0.0037 0.0081 0.0157
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0013 0.0045
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0046 0.0109 0.0473
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0081 0.0157
Brugia malayi jmjC domain containing protein 0.0037 0.008 0.0142
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0027 0.0108
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0081 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi Bromodomain containing protein 0.0074 0.0204 0.0369
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0035 0.0364
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0021 0.0034
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0707 0.2297 0.4697
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0013 0.0543
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0189 0.0387
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0011 0.0044
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0035 0.0024
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0046 0.0109 0.0554
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.007 0.019 0.0498
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trichomonas vaginalis esterase, putative 0.0036 0.0076 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.164
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Brugia malayi G protein-coupled receptor 0.0707 0.2297 0.4196
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0013 0.0054
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0435 0.1148
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0029 0.1381
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0048 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0035 0.0024
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0068 0.0057
Loa Loa (eye worm) RGS-3 protein 0.0037 0.0081 0.0209
Brugia malayi G-protein coupled receptor 0.0707 0.2297 0.4196
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0076 0.0065
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0048 0.0037
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0035 0.0094
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0013 0.0027
Echinococcus granulosus RUN 0.0019 0.0021 0.0035
Onchocerca volvulus 0.0707 0.2297 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0707 0.2297 0.4702
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0707 0.2297 0.4697
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0081 0.0166
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0153
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0707 0.2297 0.4697
Echinococcus granulosus GPCR family 2 0.0094 0.0271 0.0546
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0033 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Echinococcus granulosus geminin 0.0334 0.1064 0.2172
Mycobacterium leprae putative cytochrome p450 0.0023 0.0035 0.0364
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0033 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0035 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0068 0.0341
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0013 0.0045
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi Dopamine receptor 0.0707 0.2297 0.4196
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0035 0.0024
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.011
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0707 0.2297 0.4702
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0006 0.0007
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0029 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0303 0.0621
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0046 0.0109 0.0554
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0033 0.0134
Brugia malayi Cytochrome P450 family protein 0.0033 0.0068 0.012
Entamoeba histolytica hypothetical protein 0.0026 0.0044 0.2204
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0068 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0035 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0156
Schistosoma mansoni hypothetical protein 0.002 0.0026 0.0053
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0074 0.0205 0.0536
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0032 0.0057
Loa Loa (eye worm) neuropeptide F receptor 0.0707 0.2297 0.6086
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.089 0.4612
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus multilocularis serotonin receptor 0.0836 0.2726 0.5576
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.011 0.056
Onchocerca volvulus 0.0036 0.0076 0.0321
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0109 0.0464
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0054 0.0101
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Echinococcus granulosus allatostatin A receptor 0.0707 0.2297 0.4697
Brugia malayi Calcitonin receptor-like protein seb-1 0.0299 0.0947 0.1727
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0044 0.0124
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0021 0.0034
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0035 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi Dehydrogenases, short chain protein 2 0.0046 0.0109 0.0195
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0014 0.002
Brugia malayi AKH receptor 0.0707 0.2297 0.4196
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0046 0.0109 1
Echinococcus multilocularis tar DNA binding protein 0.019 0.0586 0.1191
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0021 0.0096
Giardia lamblia Reductase, putative 0.0046 0.0109 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0076 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Schistosoma mansoni lipoxygenase 0.0019 0.0021 0.0044
Onchocerca volvulus 0.0046 0.0109 0.0464
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0109 0.5612
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi Dehydrogenases, short chain protein 30 0.0046 0.0109 0.0195
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0048 0.079
Loa Loa (eye worm) beta-lactamase 0.0036 0.0076 0.0195
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0027 0.0048 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0044 0.0186
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0135 0.0267
Onchocerca volvulus 0.0054 0.0135 0.058
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0109 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0035 0.0024
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0109 0.5612
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0707 0.2297 0.4702
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.008
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.011 0.0217
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0407 0.0825
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Echinococcus granulosus neuropeptide Y receptor 0.0707 0.2297 0.4697
Leishmania major dehydrogenase-like protein 0.0046 0.0109 0.0554
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0011 0.0038
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0021 0.0096
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0046 0.0109 0.0214
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0327
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0081 0.0157
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0021 0.0097
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Brugia malayi Serotonin receptor 0.0707 0.2297 0.4196
Toxoplasma gondii cathepsin CPL 0.0016 0.0013 0.0027
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0012 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0387
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0014 0.0029
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Plasmodium vivax vivapain-2 0.0016 0.0013 0.0335
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Onchocerca volvulus Alhambra homolog 0.0029 0.0054 0.0223
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.0711 0.0701
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0021 0.0043
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1021 0.3339 0.6102
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Echinococcus multilocularis cysteine protease 0.0016 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0035 0.0024
Schistosoma mansoni neuropeptide F-like receptor 0.0707 0.2297 0.4702
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0021 0.0096
Brugia malayi larval opioid receptor 0.0707 0.2297 0.4196
Echinococcus multilocularis fmrfamide receptor 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0945 0.3085 0.6312
Echinococcus multilocularis dro:myosuppressin receptor 0.0707 0.2297 0.4697
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0074 0.0142
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0013 0.0095
Echinococcus granulosus expressed protein 0.0724 0.2353 0.4812
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0148 0.0756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0048 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0707 0.2297 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0033 0.008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0033 0.1592
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0026
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0011 0.0044
Echinococcus multilocularis zinc finger protein 0.0019 0.0022 0.0037
Plasmodium falciparum thioredoxin reductase 0.0046 0.011 0.5127
Leishmania major short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Onchocerca volvulus 0.0046 0.0109 0.0464
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0707 0.2297 1
Echinococcus granulosus jumonji domain containing protein 0.004 0.0091 0.0177
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0595 0.1926 1
Loa Loa (eye worm) ctsf protein 0.0016 0.0013 0.0027
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0044 0.0218
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Echinococcus granulosus microtubule associated protein 2 0.0721 0.2345 0.4796
Schistosoma mansoni alpha glucosidase 0.0036 0.0077 0.0157
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0006
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0043 0.0209
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0707 0.2297 0.4697
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0029 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Onchocerca volvulus Sepiapterin reductase homolog 0.0046 0.0109 0.0464
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0079 0.0153
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0054 0.0101
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Echinococcus multilocularis Ankyrin 0.0014 0.0005 0.0001
Mycobacterium ulcerans dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus granulosus Ankyrin 0.0014 0.0005 0.0001
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0081 0.0157
Echinococcus granulosus steroid dehydrogenase 0.0046 0.0109 0.0214
Onchocerca volvulus 0.0016 0.0013 0.0045
Brugia malayi Tachykinin-like peptides receptor 99D 0.0707 0.2297 0.4196
Onchocerca volvulus 0.0707 0.2297 1
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0013 0.0543
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Mycobacterium ulcerans hypothetical protein 0.0036 0.0076 0.0065
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0029 0.005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0035 0.0024
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0707 0.2297 0.4196
Brugia malayi A-kinase anchor protein 10, precursor 0.0037 0.0081 0.0144
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0079 0.0068
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Giardia lamblia GTOR 0.0019 0.0021 0.1017
Brugia malayi Bromodomain containing protein 0.0038 0.0084 0.0149
Loa Loa (eye worm) hypothetical protein 0.0049 0.0122 0.0317
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0192 0.0385
Onchocerca volvulus 0.0707 0.2297 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis peregrin 0.0031 0.0061 0.0117
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0305 0.8793
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0068 0.0341
Brugia malayi hypothetical protein 0.0071 0.0192 0.0347
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0189 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi Cytochrome P450 family protein 0.0085 0.0241 0.0436
Schistosoma mansoni histamine h1 receptor 0.0707 0.2297 0.4702
Brugia malayi hypothetical protein 0.0118 0.0349 0.0635
Brugia malayi G protein-coupled receptor F59B2.13 0.0707 0.2297 0.4196
Echinococcus granulosus somatostatin receptor 0.0707 0.2297 0.4697
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.0031
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0035 0.0024
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Leishmania major short chain dehydrogenase-like protein 0.0046 0.0109 0.0554
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0081 0.0157
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0044 0.0218
Brugia malayi hypothetical protein 0.0019 0.0021 0.0035
Echinococcus multilocularis conserved hypothetical protein 0.0046 0.0109 0.0214
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0217
Echinococcus granulosus neuropeptide receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0044 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0021 0.0035
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0068 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus granulosus peregrin 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0136
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0235 0.1209
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0035 0.0024
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Leishmania major cytochrome p450-like protein 0.0023 0.0035 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0004
Plasmodium vivax vivapain-2 0.0016 0.0013 0.0335
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0033 0.0157
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0995 0.3251 1
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0109 0.0214
Schistosoma mansoni myosin xvIII 0.0707 0.2297 0.4702
Schistosoma mansoni hypothetical protein 0.0071 0.0192 0.0394
Plasmodium vivax SET domain protein, putative 0.0087 0.0247 1
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0195 0.039
Toxoplasma gondii endonuclease IV APN 0.0074 0.0205 0.0618
Echinococcus granulosus tar DNA binding protein 0.019 0.0586 0.1191
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0035 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0241 0.0632
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0025 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0037 0.0081 0.035
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0011 0.0259
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Brugia malayi dehydrogenases, short chain protein 2 0.0046 0.0109 0.0195
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0192 0.0385
Echinococcus multilocularis allatostatin A receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0657 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.3981 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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