Detailed information for compound 1290042

Basic information

Technical information
  • TDR Targets ID: 1290042
  • Name: 4-methyl-N-[5-[(1-methylpyrrol-2-yl)methylide ne]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-y l]benzamide
  • MW: 357.45 | Formula: C17H15N3O2S2
  • H donors: 1 H acceptors: 2 LogP: 3.29 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)C(=O)NN1C(=S)S/C(=C\c2cccn2C)/C1=O
  • InChi: 1S/C17H15N3O2S2/c1-11-5-7-12(8-6-11)15(21)18-20-16(22)14(24-17(20)23)10-13-4-3-9-19(13)2/h3-10H,1-2H3,(H,18,21)/b14-10-
  • InChiKey: CAPJZBRXIXDIIY-UVTDQMKNSA-N  


Substructure search Similarity search

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Synonyms

  • 4-methyl-N-[(5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
  • 4-methyl-N-[5-[(1-methylpyrrol-2-yl)methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]benzamide
  • 4-methyl-N-[(5Z)-5-[(1-methylpyrrol-2-yl)methylene]-4-oxo-2-thioxo-thiazolidin-3-yl]benzamide
  • 4-methyl-N-[5-[(1-methyl-2-pyrrolyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]benzamide
  • 4-methyl-N-[(5Z)-5-[(1-methyl-2-pyrrolyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]benzamide
  • N-[(5Z)-4-keto-5-[(1-methylpyrrol-2-yl)methylene]-2-thioxo-thiazolidin-3-yl]-4-methyl-benzamide
  • N-[4-keto-5-[(1-methylpyrrol-2-yl)methylene]-2-thioxo-thiazolidin-3-yl]-4-methyl-benzamide
  • ZINC05156268
  • STOCK4S-60447
  • 4-Methyl-N-{5-[1-(1-methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzamide
  • MLS000580916
  • SMR000220301

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Homo sapiens MDM2 proto-oncogene, E3 ubiquitin protein ligase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0001 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0121 0.9815
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0095
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0011 0.0819
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.001 0.0036
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.001 0.0036
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0018 0.1389
Loa Loa (eye worm) ctsf protein 0.0017 0.0007 0.0052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0011
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0018 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0121 0.0869
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.1588 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0013 0.0001 0.0008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0114 0.0439
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0042 0.0042
Brugia malayi Ets-domain containing protein 0.0077 0.0125 0.0901
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0014 0.0002 0.0002
Brugia malayi Fli-1 protein 0.0235 0.043 0.3102
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0046 0.0046
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0009 0.0055
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0001 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0046 0.0167
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0009 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi acetyltransferase, GNAT family protein 0.0307 0.057 0.4109
Echinococcus granulosus neuropeptide s receptor 0.0455 0.0856 0.3111
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0073 0.0116 0.0837
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0014 0.0002 0.0011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0073 0.0116 0.0422
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0015 0.0005 0.005
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.002 0.0013 0.0654
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Schistosoma mansoni cytochrome P450 0.0018 0.001 0.0063
Toxoplasma gondii serine carboxypeptidase s28 protein 0.002 0.0013 0.0858
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0018 0.1389
Loa Loa (eye worm) MBCTL1 0.0066 0.0102 0.0735
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0169 0.0616
Echinococcus granulosus smad 0.0017 0.0009 0.0032
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0102 0.0102
Echinococcus multilocularis muscleblind protein 0.018 0.0324 0.0324
Echinococcus granulosus microtubule associated protein 2 0.0833 0.1588 0.5775
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0015 0.0005 0.0332
Onchocerca volvulus 0.0017 0.0007 0.0071
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0009 0.0694
Echinococcus granulosus lysosomal alpha glucosidase 0.0174 0.0312 0.1136
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.007 0.5712
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0009 0.0694
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0043 0.0157
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.002 0.0013 0.1012
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0015 0.0005 0.0332
Loa Loa (eye worm) steroid hormone receptor 0.0073 0.0116 0.0837
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0121 0.0466
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Plasmodium falciparum phd finger protein, putative 0.0035 0.0043 0.3216
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.003 0.0112
Brugia malayi hypothetical protein 0.0111 0.019 0.1368
Brugia malayi Pre-SET motif family protein 0.0064 0.0099 0.0711
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.0002 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0319 0.0593 0.4273
Echinococcus multilocularis Niemann Pick C1 protein 0.0153 0.0272 0.0272
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.007 0.0256
Schistosoma mansoni lamin 0.0081 0.0133 0.0835
Echinococcus multilocularis prolyl endopeptidase 0.0013 0.0001 0.0001
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0015 0.0005 0.0214
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0011
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.005 0.005
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0002 0.0005
Echinococcus multilocularis lamin dm0 0.0081 0.0133 0.0133
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.002 0.0013 0.0654
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.003
Trichomonas vaginalis Phospholipase C precursor, putative 0.0015 0.0005 0.005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0025 0.1952
Plasmodium vivax vivapain-2 0.0017 0.0007 0.047
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.0153 1
Echinococcus multilocularis FTZ F1 alpha 0.0073 0.0116 0.0116
Onchocerca volvulus 0.0535 0.1011 1
Schistosoma mansoni alpha-glucosidase 0.015 0.0265 0.1671
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0015 0.0005 0.0214
Schistosoma mansoni RAR-like nuclear receptor 0.0073 0.0116 0.073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0018 0.0066
Brugia malayi hypothetical protein 0.0535 0.1011 0.7286
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0319 0.0593 0.0593
Loa Loa (eye worm) prolyl oligopeptidase 0.0168 0.03 0.2166
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0046 0.0481
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0015 0.0005 0.0332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0073 0.0116 0.0837
Loa Loa (eye worm) hypothetical protein 0.0069 0.0109 0.0783
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0014 0.0002 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0073 0.0116 0.0422
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0002 0.0016
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0086 0.0856
Echinococcus multilocularis tar DNA binding protein 0.0255 0.0468 0.0468
Schistosoma mansoni lozenge 0.0067 0.0105 0.066
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0307 0.057 0.057
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0037 0.0037
Echinococcus granulosus GPCR family 2 0.0032 0.0037 0.0134
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.003 0.1937
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0073 0.0116 0.0837
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0086 0.0086
Echinococcus multilocularis lamin 0.0081 0.0133 0.0133
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0114 0.0114
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0121 0.0869
Schistosoma mansoni hypothetical protein 0.0149 0.0263 0.1656
Onchocerca volvulus 0.0022 0.0018 0.0175
Echinococcus multilocularis Smad4 0.0017 0.0009 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.019 0.069
Echinococcus multilocularis peregrin 0.0045 0.0062 0.0062
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0059 0.0428
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0121 0.9815
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0319 0.0593 0.4273
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0114 0.0439
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0695 0.5009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0099 0.0621
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0007 0.0526
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0014 0.0002 0.0011
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0102 0.0371
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0025 0.1607
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.005 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0014 0.0002 0.0016
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.002 0.0013 0.0048
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.005 0.0521
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.001 0.0653
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0046 0.0167
Onchocerca volvulus 0.003 0.0033 0.0325
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0043 0.0311
Schistosoma mansoni ap endonuclease 0.0076 0.0123 0.0773
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.001 0.0036
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0121 0.0466
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0095
Leishmania major hypothetical protein, conserved 0.0015 0.0005 0.0332
Schistosoma mansoni hypothetical protein 0.0035 0.0043 0.0272
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0009 0.0444
Loa Loa (eye worm) beta-lactamase 0.0072 0.0114 0.082
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0114 0.0439
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0018 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0073 0.0116 0.0422
Brugia malayi F/Y-rich N-terminus family protein 0.0016 0.0005 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0116 0.0834
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0061 0.044
Mycobacterium tuberculosis Conserved protein 0.0072 0.0114 0.0439
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0102 0.0102
Echinococcus granulosus neuropeptide receptor A26 0.0455 0.0856 0.3111
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0133 0.0956
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.0263 0.1896
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0071 0.5791
Schistosoma mansoni nuclear receptor 0.0034 0.0042 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Onchocerca volvulus 0.0017 0.0007 0.0071
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0015 0.0005 0.0048
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0011
Echinococcus granulosus importin subunit beta 1 0.0035 0.0042 0.0154
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.001 0.0755
Onchocerca volvulus 0.0073 0.0116 0.1148
Trypanosoma brucei RNA editing exonuclease 2 0.0015 0.0005 0.0332
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0015 0.0005 0.0035
Entamoeba histolytica hypothetical protein 0.0111 0.019 1
Onchocerca volvulus 0.0015 0.0005 0.0048
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0045
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0014 0.0002 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0064 0.0463
Schistosoma mansoni Smad4 0.0017 0.0009 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Leishmania major pantothenate kinase subunit, putative 0.0018 0.0011 0.0819
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0121 0.0466
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0009 0.0444
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0084 0.6245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0037 0.0266
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.0042 0.0299
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Brugia malayi prolyl oligopeptidase family protein 0.0057 0.0084 0.0609
Toxoplasma gondii ABC1 family protein 0.0072 0.0114 0.7428
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0102 0.0735
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0018 0.0066
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0018 0.1158
Schistosoma mansoni hypothetical protein 0.0372 0.0695 0.4373
Echinococcus multilocularis smad 0.0017 0.0009 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.0073 0.0116 0.0837
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0084 0.0323
Entamoeba histolytica Ran family GTPase 0.0026 0.0025 0.126
Echinococcus multilocularis expressed protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.002 0.0013 0.0137
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.001 0.0036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0121 0.6337
Brugia malayi hypothetical protein 0.0034 0.0042 0.0299
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0114 0.0716
Plasmodium vivax exodeoxyribonuclease III, putative 0.0015 0.0005 0.0315
Echinococcus granulosus peregrin 0.0045 0.0062 0.0226
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0014 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0103 0.0744
Giardia lamblia Histone acetyltransferase GCN5 0.0082 0.0134 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0123 0.0886
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0005 0.0035
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.007 0.0256
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.002 0.0013 0.1012
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0018 0.1389
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0005 0.0035
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0025 0.1952
Loa Loa (eye worm) hypothetical protein 0.0038 0.0049 0.0357
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.005 0.2596
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0059 0.0428
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0073 0.0116 0.0837
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0014 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.005 0.402
Brugia malayi hypothetical protein 0.0038 0.0049 0.0357
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.0042 0.0151
Brugia malayi RNA, U transporter 1 0.0099 0.0167 0.1202
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0009 0.0032
Brugia malayi Ets-domain containing protein 0.0077 0.0125 0.0901
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.034
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0121 0.0466
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0075
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0049 0.0357
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Onchocerca volvulus Bile acid receptor homolog 0.0073 0.0116 0.1148
Entamoeba histolytica hypothetical protein 0.0111 0.019 1
Brugia malayi MH2 domain containing protein 0.0017 0.0009 0.0063
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0025 0.0177
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0007 0.0026
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0009 0.0009
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0018 0.0066
Echinococcus granulosus lamin 0.0081 0.0133 0.0482
Onchocerca volvulus 0.021 0.0381 0.3772
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0052
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0073 0.0116 0.073
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0168 0.03 0.2973
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0073 0.0116 0.073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0242 0.0444 0.0444
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0018 0.0066
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0114 0.0439
Schistosoma mansoni hypothetical protein 0.0018 0.001 0.0063
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0242 0.0444 0.1615
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0458 0.0861 0.3345
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.001 0.0036
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0018 0.0066
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0015 0.0005 0.036
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0005 0.0035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0123 1
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0015 0.0005 0.005
Loa Loa (eye worm) hypothetical protein 0.0069 0.0109 0.0784
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0073 0.0116 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0073 0.0116 0.0837
Brugia malayi jmjC domain containing protein 0.0115 0.0198 0.1429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0084 0.5472
Entamoeba histolytica G protein alpha subunit, putative 0.0014 0.0002 0.0039
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.003 0.2104
Brugia malayi PHD-finger family protein 0.0035 0.0043 0.0311
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0078 0.0299
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0009 0.0063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0007
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0007
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.0153 0.16
Toxoplasma gondii cathepsin CPL 0.0017 0.0007 0.047
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.005 0.0521
Leishmania major importin beta-1 subunit, putative 0.0028 0.003 0.2365
Schistosoma mansoni bromodomain containing protein 0.0069 0.0109 0.0687
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0131 0.0824
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.005 0.0521
Brugia malayi hypothetical protein 0.0038 0.0049 0.0357
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0604
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0102 0.0372
Mycobacterium leprae putative cytochrome p450 0.0018 0.001 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0073 0.0116 0.0837
Mycobacterium ulcerans AcrR family transcriptional regulator 0.1342 0.2574 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.005 0.0521
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.007 0.0508
Loa Loa (eye worm) hypothetical protein 0.0039 0.0051 0.0368
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Leishmania major cytochrome p450-like protein 0.0018 0.001 0.0755
Echinococcus granulosus zinc finger protein 0.0027 0.0026 0.0096
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0018 0.0185
Schistosoma mansoni nocturnin 0.0015 0.0005 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0018 0.1389
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.005 0.0359
Loa Loa (eye worm) hypothetical protein 0.0101 0.0171 0.123
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0005 0.0035
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0114 0.082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0052
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0051 0.0186
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.0042 0.0299
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0015 0.0005 0.005
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.001 0.0036
Brugia malayi Cytochrome P450 family protein 0.0018 0.001 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0073 0.0116 0.0837
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0007 0.0071
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.001 0.0036
Brugia malayi Serine protease Z688.6 precursor 0.002 0.0013 0.0095
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0123 1
Loa Loa (eye worm) DR-78 0.0034 0.0042 0.0299
Schistosoma mansoni retinoic acid receptor RXR 0.0073 0.0116 0.073
Brugia malayi PHD-finger family protein 0.0032 0.0037 0.0263
Loa Loa (eye worm) hypothetical protein 0.0038 0.0049 0.0357
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.001 0.0036
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Loa Loa (eye worm) hypothetical protein 0.0038 0.0049 0.0357
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0109 0.0186 0.1171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0123 0.0474
Loa Loa (eye worm) CYP4Cod1 0.0018 0.001 0.0072
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Brugia malayi nuclear receptor NHR-67 0.0034 0.0042 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0046 0.0481
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0075 0.0121 0.0466
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0009 0.0599
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.005 0.0181
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0168 0.03 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni ap endonuclease 0.0076 0.0123 0.0773
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0042 0.0299
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0037 0.0266
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0018 0.0066
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0018 0.0066
Schistosoma mansoni hypothetical protein 0.0032 0.0037 0.0232
Onchocerca volvulus 0.0017 0.0007 0.0071
Schistosoma mansoni hypothetical protein 0.0032 0.0037 0.0232
Trypanosoma brucei ISWI complex protein 0.0015 0.0004 0.0256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Echinococcus multilocularis zinc finger protein 0.0027 0.0026 0.0026
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0009 0.0688
Brugia malayi Smad1 0.0017 0.0009 0.0063
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0042 0.0299
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0011
Schistosoma mansoni gabp alpha 0.0077 0.0125 0.0787
Onchocerca volvulus 0.0081 0.0133 0.1312
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0086 0.0545
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0102 0.0642
Onchocerca volvulus 0.0507 0.0956 0.9464
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0137
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0049 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0009 0.0066
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0064 0.0233
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0071
Brugia malayi Bromodomain containing protein 0.0045 0.0062 0.0448
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0087 0.7071
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0018 0.0066
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0018 0.1389
Onchocerca volvulus 0.0017 0.0007 0.0071
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.001 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0073 0.0116 0.0837
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0125 0.0454
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0604
Brugia malayi follicle stimulating hormone receptor 0.0485 0.0914 0.6587
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Schistosoma mansoni nuclear receptor 0.0034 0.0042 0.0261
Entamoeba histolytica hypothetical protein 0.0028 0.003 0.1528
Loa Loa (eye worm) hypothetical protein 0.0119 0.0205 0.1475
Echinococcus granulosus histone acetyltransferase KAT2B 0.0296 0.0549 0.1995
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.003 0.354
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0171 0.123
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Echinococcus granulosus expressed protein 0.0014 0.0002 0.0005
Brugia malayi cytochrome P450 0.0018 0.001 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0018 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0001 0.00000042445
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0001 0.0002
Schistosoma mansoni ran 0.0026 0.0025 0.0155
Echinococcus granulosus Niemann Pick C1 protein 0.0107 0.0183 0.0665
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0007 0.0045
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0051 0.0051
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0057 0.0084 0.0084
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0014 0.0002 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.003 0.031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.003 0.031
Loa Loa (eye worm) fibroinase 0.0017 0.0007 0.0052
Loa Loa (eye worm) TAR-binding protein 0.0255 0.0468 0.3375
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0125 0.0125
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0123 0.8024
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0003 0.011
Entamoeba histolytica hypothetical protein 0.0028 0.003 0.1527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0009 0.0688
Schistosoma mansoni zinc finger protein 0.0027 0.0026 0.0167
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0014 0.0002 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0042 0.0151
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0526
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0114 0.0439
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.003 0.1937
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0086 0.0545
Brugia malayi Glycosyl hydrolases family 31 protein 0.0174 0.0312 0.2252
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0049 0.018
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.0042 0.0261
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Echinococcus granulosus intermediate filament protein 0.0081 0.0133 0.0482
Onchocerca volvulus 0.01 0.0169 0.1676
Schistosoma mansoni hypothetical protein 0.0044 0.0061 0.0384
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0018 0.0064
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0015 0.0005 0.0332
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.005 0.3256
Toxoplasma gondii prolyl endopeptidase 0.0013 0.0001 0.005
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0005 0.005
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0114 0.7428
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.002 0.0013 0.0137
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0009 0.0033
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0025 0.0089
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0312 0.0312
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0123 0.0447
Giardia lamblia hypothetical protein 0.0015 0.0005 0.0304
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0005 0.005
Onchocerca volvulus 0.0014 0.0002 0.0015
Brugia malayi MAP kinase sur-1 0.0049 0.007 0.0508
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0114 0.0716
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.0002 0.0009
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.0312 0.0312
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0007 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0046 0.0481
Schistosoma mansoni patched 1 0.0046 0.0064 0.0404
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0046 0.0167
Trypanosoma brucei glucosidase, putative 0.0039 0.005 0.402
Echinococcus granulosus geminin 0.0178 0.0319 0.1161
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.001 0.0755
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0367 0.0685 0.0685
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.001 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0073 0.0116 0.073
Leishmania major hypothetical protein, conserved 0.0015 0.0005 0.0332
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0042 0.0151
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0018 0.1158
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0073 0.0116 0.0422
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.0042 0.0299
Trichomonas vaginalis set domain proteins, putative 0.0507 0.0956 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni carbon catabolite repressor protein 0.0015 0.0005 0.003
Schistosoma mansoni cript-related 0.0015 0.0005 0.003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0073 0.0116 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi hypothetical protein 0.0034 0.0042 0.0299
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0009 0.0688
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0123 0.9152
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0001 0.0006
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0123 0.6457
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0042 0.0261
Schistosoma mansoni alpha-glucosidase 0.015 0.0265 0.1671
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0009 0.0009
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0009 0.0688
Onchocerca volvulus Protein ultraspiracle homolog 0.0073 0.0116 0.1148
Plasmodium falciparum DNase I-like protein, putative 0.0015 0.0005 0.036
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0073 0.0116 0.0837
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0073 0.0116 0.0116
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0046 0.029
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0042 0.0261
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0025 0.0025
Giardia lamblia Thymus-specific serine protease precursor 0.002 0.0013 0.0927
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.0593 0.3731
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0114 0.1189
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0107 0.0183 0.963
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0604
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0098 0.7944
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.005 0.2596
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0003 0.0171
Echinococcus granulosus Dipeptidyl peptidase 9 0.0057 0.0084 0.0307
Schistosoma mansoni ran 0.0026 0.0025 0.0155
Echinococcus multilocularis ecdysone induced protein 78C 0.0073 0.0116 0.0116
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0111
Brugia malayi hypothetical protein 0.0014 0.0002 0.0011
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.0002 0.0009
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0018 0.1389
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0009 0.0066
Echinococcus granulosus ecdysone induced protein 78C 0.0073 0.0116 0.0422
Brugia malayi Serine protease Z688.6 precursor 0.002 0.0013 0.0095
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.0002 0.0009
Brugia malayi Cytochrome P450 family protein 0.0018 0.001 0.0072
Trypanosoma brucei protein kinase, putative 0.0049 0.007 0.5712
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.001 0.0036
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.001 0.0036
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.0153 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.007 0.5712
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0319 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0688
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0022 0.0158
Echinococcus granulosus neutral sphingomyelinase 0.0015 0.0005 0.0018
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.001 0.0036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0116 0.073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0073 0.0116 0.073
Schistosoma mansoni hypothetical protein 0.0032 0.0037 0.0232
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0121 0.0466
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Brugia malayi ecdysone receptor 0.0034 0.0042 0.0299
Schistosoma mansoni cellular tumor antigen P53 0.021 0.0381 0.24
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Loa Loa (eye worm) oxidoreductase 0.0022 0.0018 0.0128
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0526
Schistosoma mansoni coup transcription factor 0.0073 0.0116 0.073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni neutral sphingomyelinase 0.0015 0.0005 0.003
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0009 0.0688
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.005 0.402
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0018 0.0185
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0015 0.0005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0005 0.036
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0043 0.0272
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0086 0.0624
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.001 0.0036
Leishmania major cathepsin L-like protease 0.0063 0.0098 0.7944
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0084 0.0323
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0073 0.0116 0.0837
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.007 0.4605
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.001 0.0072
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0125 0.0901
Brugia malayi Bromodomain containing protein 0.0081 0.0131 0.0946
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Onchocerca volvulus 0.0298 0.0551 0.5457
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0073 0.0116 0.0422
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.0042 0.0042
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0025 0.1834
Echinococcus granulosus prolyl endopeptidase 0.0013 0.0001 0.0003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.003 0.2365
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Schistosoma mansoni hypothetical protein 0.0366 0.0683 0.4299
Entamoeba histolytica hypothetical protein 0.0111 0.019 1
Mycobacterium ulcerans hypothetical protein 0.0075 0.0121 0.0466
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.001 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0073 0.0116 0.0837
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0064 0.0233
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0073 0.0116 0.0116
Leishmania major cathepsin L-like protease 0.0063 0.0098 0.7944
Leishmania major RNA-editing complex protein MP100, putative 0.0015 0.0005 0.0332
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0022 0.0138
Echinococcus multilocularis neutral sphingomyelinase 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0298 0.0551 0.3976
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0015 0.0005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0021
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0007
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0046 0.0046
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.001 0.0755
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0114 0.0439
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0003 0.0171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Brugia malayi prolyl oligopeptidase family protein 0.0168 0.03 0.2166
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.112
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0114 0.1189
Entamoeba histolytica hypothetical protein 0.0111 0.019 1
Mycobacterium tuberculosis Probable exported protein 0.0015 0.0005 0.0016
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0009 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.001 0.0072
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0025 0.1952
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.002 0.0013 0.0654
Echinococcus multilocularis deoxyribonuclease 1 2 0.0015 0.0005 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0152 0.0959
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0604
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.0042 0.0151
Brugia malayi intermediate filament protein 0.0081 0.0133 0.0956
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0018 0.1158
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0133 0.0956
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0018 0.0066
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0001 0.0005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.007 0.007
Echinococcus granulosus snurportin 1 0.0372 0.0695 0.2526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0098 0.7944
Onchocerca volvulus Huntingtin homolog 0.0119 0.0205 0.2025
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0043 0.0156
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0042 0.341
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0114 0.1189
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0005 0.0035
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0005 0.0332
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0123 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0073 0.0116 0.0837
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.001 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0123 0.1284
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.001 0.0036
Leishmania major endonuclease/exonuclease protein-like protein 0.0015 0.0005 0.0332
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.001 0.0036
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0005 0.0315
Plasmodium falciparum importin beta, putative 0.0035 0.0042 0.3161
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.019 0.019
Trichomonas vaginalis importin beta-1, putative 0.0028 0.003 0.031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.007 0.5712
Schistosoma mansoni synaptojanin 0.0015 0.0005 0.003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0123 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Schistosoma mansoni hypothetical protein 0.0044 0.0061 0.0384
Brugia malayi ecdysteroid receptor 0.0073 0.0116 0.0837
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0073 0.0116 0.0422
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0046 0.371
Schistosoma mansoni thyroid hormone receptor 0.0073 0.0116 0.073
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Plasmodium vivax vivapain-2 0.0017 0.0007 0.047
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0009
Schistosoma mansoni alpha glucosidase 0.0039 0.005 0.0314
Echinococcus granulosus synaptojanin 1 0.0015 0.0005 0.0018
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0015 0.0005 0.036
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.002 0.0013 0.0083
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0002 0.0005
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.0042 0.0299
Brugia malayi Pre-SET motif family protein 0.0445 0.0837 0.6037
Brugia malayi mbt repeat family protein 0.0058 0.0086 0.0624
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0037 0.0037
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0005 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0064 0.0671
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0018 0.0066
Echinococcus granulosus tumor protein p63 0.1434 0.275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0002 0.0002
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0018 0.0112
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.0042 0.0151
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0109 0.0783
Loa Loa (eye worm) Smad1 0.0017 0.0009 0.0063
Brugia malayi Bromodomain containing protein 0.0045 0.0062 0.0446
Loa Loa (eye worm) hypothetical protein 0.0035 0.0042 0.0306
Schistosoma mansoni survival motor neuron protein 0.0149 0.0263 0.1656
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0114 0.0439
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0075 0.0121 0.0869
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0005 0.005
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0045
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0535 0.1011 0.7286
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0037 0.0266
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Brugia malayi Cytochrome P450 family protein 0.0018 0.001 0.0072
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0131 0.0476
Loa Loa (eye worm) fli-1 protein 0.0235 0.043 0.3102
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0061 0.0385
Loa Loa (eye worm) hypothetical protein 0.008 0.013 0.0935
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0002 0.0016
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0123 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.0593 0.3731
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0114 0.0413
Entamoeba histolytica cysteine protease, putative 0.0017 0.0007 0.034
Loa Loa (eye worm) hypothetical protein 0.0107 0.0183 0.1318
Onchocerca volvulus 0.0072 0.0114 0.1125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.001 0.0755
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0073 0.0116 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Onchocerca volvulus 0.0149 0.0263 0.2602
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0025
Loa Loa (eye worm) RNA binding protein 0.0255 0.0468 0.3375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.0593 0.3731
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0122 0.0883
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0018 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0073 0.0116 0.0837
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0018 0.0066
Brugia malayi TAR-binding protein 0.0255 0.0468 0.3375
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.001 0.0036
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Loa Loa (eye worm) hypothetical protein 0.0046 0.0064 0.0463
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0018 0.0897
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.005 0.0521
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.007 0.5712
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0073 0.0116 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0007 0.0536
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0198 0.0198
Brugia malayi MH1 domain containing protein 0.0017 0.0009 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.001 0.0036
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0015 0.0005 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.001 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0005 0.0332
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0018 0.0066
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.0042 0.0261
Brugia malayi beta-lactamase 0.0072 0.0114 0.082
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0116 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Echinococcus multilocularis tumor protein p63 0.1434 0.275 0.275
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0014 0.0002 0.0016
Onchocerca volvulus 0.0034 0.0042 0.0411
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0018 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0009 0.0009
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0007 0.0052
Loa Loa (eye worm) prolyl oligopeptidase 0.0013 0.0001 0.0006
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0086 0.0314
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0049 0.0357
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0075 0.0121 0.0466
Echinococcus multilocularis survival motor neuron protein 1 0.0729 0.1387 0.1387
Echinococcus multilocularis geminin 0.0178 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.0178 0.0319 0.201
Giardia lamblia GTOR 0.0018 0.0009 0.063
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0015 0.0005 0.005
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.0042 0.0299
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0086 0.0086
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.0042 0.0299
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0009 0.0033
Onchocerca volvulus Putative neutral sphingomyelinase 0.0015 0.0005 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.0042 0.0299
Brugia malayi nuclear receptor RXR 0.0034 0.0042 0.0299
Echinococcus granulosus traf and tnf receptor associated protein 0.0015 0.0005 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Schistosoma mansoni tar DNA-binding protein 0.0255 0.0468 0.2947
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0075
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0046 0.3395
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0018 0.1389
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0018 0.1389
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0046 0.371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Brugia malayi nuclear receptor RXR 0.0038 0.0049 0.0357
Onchocerca volvulus 0.0014 0.0002 0.0015
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0002 0.0011
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0009 0.0688
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Leishmania major cytochrome p450-like protein 0.0018 0.001 0.0755
Schistosoma mansoni smad 0.0017 0.0009 0.0055
Plasmodium falciparum peptidase, putative 0.0013 0.0001 0.0058
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0049 0.0357
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.005 0.0521
Onchocerca volvulus 0.0064 0.0099 0.0976
Echinococcus multilocularis GPCR, family 2 0.0032 0.0037 0.0037
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0018 0.0066
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0099 0.6445
Leishmania major hypothetical protein, conserved 0.0015 0.0004 0.0256
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0073 0.0116 0.0422
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0168 0.03 0.1891
Loa Loa (eye worm) MH2 domain-containing protein 0.0256 0.047 0.3387
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0006
Giardia lamblia PHD finger protein 15 0.0035 0.0043 0.3177
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.003 0.1937
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.001 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0485 0.0914 0.6587
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Schistosoma mansoni tar DNA-binding protein 0.0255 0.0468 0.2947
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0001 0.00000042445
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0114 0.0439
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0607
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.005 0.0359
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0022 0.008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0078 0.0299
Mycobacterium ulcerans TetR family transcriptional regulator 0.1342 0.2574 1
Schistosoma mansoni synaptojanin 0.0015 0.0005 0.003
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0012 0.0043
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0042 0.2769
Mycobacterium ulcerans transcriptional regulator 0.1342 0.2574 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0058 0.0086 0.0624
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.003 0.2366
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0009 0.0688
Schistosoma mansoni hypothetical protein 0.0044 0.0061 0.0384
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0018 0.0066
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0367 0.0685 0.4312
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0015 0.0005 0.0214
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Onchocerca volvulus 0.0072 0.0114 0.1125
Loa Loa (eye worm) hypothetical protein 0.0119 0.0205 0.1475
Brugia malayi MH2 domain containing protein 0.0256 0.047 0.3387
Brugia malayi hypothetical protein 0.0298 0.0551 0.3976
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0043 0.2818
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.001 0.0036
Loa Loa (eye worm) G protein alpha subunit 3 0.0014 0.0002 0.0011
Brugia malayi Importin beta-1 subunit 0.0035 0.0042 0.0306
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0035
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0013 0.0001 0.0008
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0002 0.0005
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0169 0.1066
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0018 0.1321
Schistosoma mansoni zinc finger protein 0.0015 0.0004 0.0025
Brugia malayi Cytochrome P450 family protein 0.0076 0.0122 0.0883
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0526
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni hypothetical protein 0.0178 0.0319 0.201
Trypanosoma cruzi ISWI complex protein 0.0015 0.0004 0.0256
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0086 0.0314
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0037 0.0134
Loa Loa (eye worm) hypothetical protein 0.0535 0.1011 0.7286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0123 0.1284
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Onchocerca volvulus 0.0014 0.0002 0.0015
Echinococcus multilocularis neuropeptide receptor A26 0.0455 0.0856 0.0856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0022 0.0229
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.001 0.0036
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0255 0.0468 0.3375
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0098 0.7944
Trypanosoma brucei cytochrome P450, putative 0.0018 0.001 0.0755
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.001 0.0755
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0081 0.0133 0.1312
Loa Loa (eye worm) cysteine protease 0.0017 0.0007 0.0052
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0073 0.0116 0.0116
Plasmodium falciparum histone acetyltransferase GCN5 0.0082 0.0134 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0046 0.2395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0001 0.005
Echinococcus granulosus cathepsin l1 0.0017 0.0007 0.0026
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.001 0.0036
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0042 0.0411
Onchocerca volvulus 0.0017 0.0007 0.0071
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.0121 0.0466
Onchocerca volvulus Prolyl endopeptidase homolog 0.0013 0.0001 0.0008
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0005 0.0214
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0128
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0023 0.0165
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0088
Leishmania major hypothetical protein, conserved 0.0072 0.0114 0.9252
Brugia malayi hypothetical protein 0.0119 0.0205 0.1475
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0018 0.0111
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0043 0.0043
Echinococcus granulosus survival motor neuron protein 1 0.0729 0.1387 0.5043
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0009 0.0688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0073 0.0116 0.0116
Brugia malayi Muscleblind-like protein 0.018 0.0324 0.2338
Giardia lamblia Inositol 5-phosphatase 4 0.0015 0.0005 0.0304
Brugia malayi G-protein alpha subunit 0.0014 0.0002 0.0011
Echinococcus granulosus muscleblind protein 0.018 0.0324 0.1179
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0319 0.0593 0.2155
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0114 0.9252
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0198 0.0721
Echinococcus multilocularis synaptojanin 1 0.0015 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Loa Loa (eye worm) hypothetical protein 0.0081 0.0131 0.0944
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0003 0.0171
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.018 0.0324 0.2338
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0169 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0007 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0131 0.0824
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0049 0.0312
Brugia malayi RNA recognition motif domain containing protein 0.0255 0.0468 0.3375
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0169 0.1221
Echinococcus multilocularis X box binding protein 1 0.0297 0.055 0.055
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.001 0.0755
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.001 0.0036
Mycobacterium tuberculosis Conserved protein 0.0072 0.0114 0.0439
Brugia malayi mbt repeat family protein 0.0058 0.0086 0.0624
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.002 0.0013 0.0013
Plasmodium vivax SET domain protein, putative 0.0064 0.0099 0.6445
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0009 0.0066
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0688
Schistosoma mansoni hypothetical protein 0.0032 0.0037 0.0232
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0018 0.0066
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0075 0.0121 0.0466
Leishmania major cathepsin L-like protease 0.0063 0.0098 0.7944
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0035
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0056 0.0084 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0381 0.2749
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0025 0.1607
Brugia malayi MH2 domain containing protein 0.0017 0.0009 0.0063
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.003
Echinococcus granulosus Smad4 0.0017 0.0009 0.0032
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0046 0.371
Giardia lamblia Serine peptidase, putative 0.002 0.0013 0.0927
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0001 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Echinococcus multilocularis acylamino acid releasing enzyme 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0729 0.1387 1
Onchocerca volvulus 0.0034 0.0042 0.0411
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Echinococcus multilocularis protein patched 0.0046 0.0064 0.0064
Echinococcus granulosus Niemann Pick C1 protein 0.0153 0.0272 0.0989
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0007
Mycobacterium tuberculosis Conserved protein 0.0072 0.0114 0.0439
Echinococcus multilocularis traf and tnf receptor associated protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.001 0.0036
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.003 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0078 0.0299
Echinococcus multilocularis muscleblind protein 1 0.018 0.0324 0.0324
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0114 0.1189
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0018 0.1389
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0319 0.0593 0.2155
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0057 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0055
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0002 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0107 0.0183 0.0183
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0014 0.0002 0.0011
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0009 0.0058
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.019 0.1195
Toxoplasma gondii hypothetical protein 0.0013 0.0001 0.005
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0042 0.0042
Entamoeba histolytica acetyltransferase, GNAT family 0.0082 0.0134 0.7055
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0121 0.9815
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0307 0.057 0.3587
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0002 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0005 0.0315
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0098 0.7944
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0018 0.0128
Schistosoma mansoni nuclear hormone receptor 0.0073 0.0116 0.073
Brugia malayi Niemann-Pick C1 protein precursor 0.0107 0.0183 0.1318
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Brugia malayi steroid hormone receptor 0.0073 0.0116 0.0837
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0171 0.123
Brugia malayi jmjC domain containing protein 0.0044 0.0061 0.044
Onchocerca volvulus 0.0075 0.0121 0.1193
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.002 0.0013 0.1012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0048 0.0347
Loa Loa (eye worm) hypothetical protein 0.0081 0.0133 0.0956
Loa Loa (eye worm) hypothetical protein 0.0173 0.031 0.2238
Echinococcus multilocularis protein dispatched 1 0.0053 0.0077 0.0077
Toxoplasma gondii exonuclease III APE 0.0076 0.0123 0.8024
Brugia malayi hypothetical protein 0.0043 0.0059 0.0423
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0007 0.0052
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0001 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0005 0.0315
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0007 0.0536
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0114 0.082
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.003 0.221
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0014 0.0002 0.0011
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0526
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0102 0.0371
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.007 0.5712
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.001 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.005 0.402
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0133 0.0956
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0009 0.0058
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.005 0.0521
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.007 0.0737
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.001 0.0036
Brugia malayi CCR4 0.0015 0.0005 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0121 0.0466
Brugia malayi conserved hypotetical protein 0.0034 0.0042 0.0299
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0018 0.0064
Onchocerca volvulus 0.0017 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0049 0.007 0.0505
Echinococcus granulosus tar DNA binding protein 0.0255 0.0468 0.1702
Echinococcus multilocularis expressed conserved protein 0.0101 0.017 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0014 0.0002 0.0011
Schistosoma mansoni hypothetical protein 0.0069 0.0109 0.0684
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.007 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0014 0.0101
Echinococcus granulosus lamin dm0 0.0081 0.0133 0.0482
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0018 0.0066
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0174 0.0312 0.2252
Brugia malayi nuclear hormone receptor 0.0073 0.0116 0.0837
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0114 0.1189
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0123 0.0474
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0075 0.0121 0.0466
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0025 0.0177
Schistosoma mansoni zinc finger protein 0.0034 0.0042 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Schistosoma mansoni hypothetical protein 0.0297 0.055 0.3466
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0123 0.9157
Trypanosoma cruzi ISWI complex protein 0.0015 0.0004 0.0256
Echinococcus multilocularis Protein lozenge 0.0067 0.0105 0.0105
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0073 0.0116 0.1148
Schistosoma mansoni hypothetical protein 0.0044 0.0061 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.0301 0.3149
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0005 0.0332
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.001 0.0036
Brugia malayi RNA binding protein 0.0255 0.0468 0.3375
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0022 0.1735
Schistosoma mansoni intermediate filament proteins 0.0081 0.0133 0.0835
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0009 0.0032
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0061 0.0385
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0043 0.2818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0073 0.0116 0.0837
Loa Loa (eye worm) hypothetical protein 0.0043 0.0059 0.0423
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0002 0.0002
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0003 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0137
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0007 0.0536
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.0002 0.0009
Brugia malayi beta-lactamase family protein 0.0072 0.0114 0.082
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0046 0.371
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0052
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.1342 0.2574 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Loa Loa (eye worm) hypothetical protein 0.0075 0.0121 0.0869
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0046 0.0332
Loa Loa (eye worm) hypothetical protein 0.0038 0.0049 0.0357
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.001 0.0755
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0042 0.0151
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0025 0.1786
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0018 0.0128
Brugia malayi tailless protein 0.0034 0.0042 0.0299
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0014 0.0002 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0255 0.0468 0.2947
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0057 0.0084 0.6852
Brugia malayi hypothetical protein 0.0729 0.1387 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.0002 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0099 0.0621
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.007 0.0737
Leishmania major hypothetical protein, conserved 0.0015 0.0005 0.0332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Loa Loa (eye worm) hypothetical protein 0.006 0.0092 0.0662
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.007 0.5228
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0315
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0005 0.0332
Onchocerca volvulus 0.0022 0.0018 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.007 0.0737
Loa Loa (eye worm) hypothetical protein 0.0038 0.0049 0.0357
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0057 0.0084 0.5514
Echinococcus multilocularis 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0035
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0002 0.0016
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.007 0.0737
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0114 0.9252
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0018 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0121 0.0869
Mycobacterium ulcerans hypothetical protein 0.0072 0.0114 0.0439
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.0042 0.0261
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0094 0.0342
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0073 0.0116 0.0422
Loa Loa (eye worm) acetyltransferase 0.0307 0.057 0.4109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0015 0.0005 0.003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0073 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0075 0.0121 0.0869
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.1342 0.2574 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0123 1
Echinococcus multilocularis snurportin 1 0.0372 0.0695 0.0695
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.001 0.0036
Loa Loa (eye worm) transcription factor SMAD2 0.0256 0.047 0.3387
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0007 0.0026
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.0002 0.0009
Brugia malayi MH1 domain containing protein 0.0017 0.0009 0.0063
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0005 0.0005
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.003 0.2366
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.001 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0171 0.123
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.007 0.0444
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0043 0.2818
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.005 0.0521
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0099 0.0099
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0002 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0042 0.0042
Echinococcus multilocularis musashi 0.0081 0.0133 0.0133
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0153 0.0557
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0018 0.1158
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0072 0.0114 0.082
Mycobacterium ulcerans lipase LipD 0.0072 0.0114 0.0439
Brugia malayi nuclear hormone receptor 0.0034 0.0042 0.0299
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.1588 0.1588
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0095
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0013 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0048 0.0347
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0688
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0013 0.0001 0.005
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0014 0.0002 0.0016
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.001 0.0036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0121 0.6337
Loa Loa (eye worm) hypothetical protein 0.0066 0.0102 0.0735
Mycobacterium ulcerans beta-lactamase 0.0072 0.0114 0.0439
Schistosoma mansoni importin beta-1 0.0035 0.0042 0.0267
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.001 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0343
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0005 0.036
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.0042 0.0042
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.0153 1
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0015 0.0005 0.0332
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Echinococcus granulosus X box binding protein 1 0.0297 0.055 0.2001
Onchocerca volvulus 0.0022 0.0018 0.0175
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0073 0.0116 0.073
Loa Loa (eye worm) cytochrome P450 0.0018 0.001 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0049 0.0312
Onchocerca volvulus 0.0101 0.017 0.1683
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0114 0.0439
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.001 0.0036
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0003 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.007 0.5712
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0037 0.0134
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Echinococcus granulosus acylamino acid releasing enzyme 0.0013 0.0001 0.0003
Onchocerca volvulus 0.0072 0.0114 0.1125
Schistosoma mansoni tar DNA-binding protein 0.0255 0.0468 0.2947
Loa Loa (eye worm) hypothetical protein 0.0056 0.0084 0.0604
Onchocerca volvulus 0.002 0.0013 0.013
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0014 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.01 0.0169 0.1221
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0009 0.0063
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0022 0.1735
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.001 0.0036
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0061 0.0222
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.0153 0.16
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0018 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0073 0.0116 0.0837
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0018 0.0066
Echinococcus multilocularis neuropeptide s receptor 0.0455 0.0856 0.0856
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.001 0.0036
Brugia malayi photoreceptor-specific nuclear receptor 0.0073 0.0116 0.0837
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0005 0.0332
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0003 0.003
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0022 0.1434
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0042 0.341
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0078 0.0299
Onchocerca volvulus 0.0017 0.0007 0.0071
Echinococcus granulosus expressed conserved protein 0.0101 0.017 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0255 0.0468 0.2947
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.007 0.5712
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.001 0.0036
Leishmania major cytochrome p450-like protein 0.0018 0.001 0.0755
Brugia malayi PHD-finger family protein 0.0013 0.0001 0.0006
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.003 0.0112
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0009 0.0688
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.001 0.0036
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.001 0.0036
Loa Loa (eye worm) runx1 0.0067 0.0105 0.0756
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.0002 0.0009
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0005 0.0018
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0003 0.003
Schistosoma mansoni steroid hormone receptor ad4bp 0.0073 0.0116 0.073
Loa Loa (eye worm) hypothetical protein 0.0047 0.0066 0.0479
Onchocerca volvulus Alhambra homolog 0.0035 0.0043 0.0427
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0057 0.0084 0.0531
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0128
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0123 0.0886
Brugia malayi beta-lactamase family protein 0.0072 0.0114 0.082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0073 0.0116 0.0837
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0057 0.0084 0.6852
Schistosoma mansoni hypothetical protein 0.0111 0.019 0.1195
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0367 0.0685 0.249
Brugia malayi CHE-14 protein 0.0046 0.0064 0.0463
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0055
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0018 0.0066
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.0002 0.0009
Schistosoma mansoni ets-related 0.0235 0.043 0.2709
Entamoeba histolytica acyl-coA synthetase, putative 0.0075 0.0121 0.6337
Onchocerca volvulus Huntingtin homolog 0.0119 0.0205 0.2025
Schistosoma mansoni smad1 5 8 and 0.0017 0.0009 0.0055
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0168 0.03 0.1092
Plasmodium vivax importin-beta 2, putative 0.0035 0.0042 0.2769
Brugia malayi Serine carboxypeptidase S28 family protein 0.002 0.0013 0.0095
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0837
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0526
Loa Loa (eye worm) hypothetical protein 0.018 0.0324 0.2338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0098 0.7944
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0114 0.9252
Echinococcus granulosus jumonji domain containing protein 0.0049 0.007 0.0254
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0014 0.0002 0.0011
Brugia malayi nuclear receptor NHR-88 0.0073 0.0116 0.0837
Mycobacterium leprae conserved hypothetical protein 0.0028 0.003 0.0112
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.0042 0.0042
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0114 0.0439
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0018 0.0128
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0005 0.0035
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0015 0.1196
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0299
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0057 0.0084 0.6852
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0015 0.0005 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0009 0.0066
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0057 0.0084 0.6852
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0086 0.0545
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0007 0.0045
Leishmania major GTP-binding protein, putative 0.0026 0.0025 0.1952
Loa Loa (eye worm) hypothetical protein 0.0032 0.0037 0.0266
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.002 0.0013 0.0137
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0123 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0173 0.031 0.2238
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0015 0.0005 0.005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0445 0.0837 0.6037
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.002 0.0013 0.0137
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0005 0.0214
Brugia malayi nuclear receptor NHR-88 0.0034 0.0042 0.0299
Schistosoma mansoni lamin 0.0081 0.0133 0.0835
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0046 0.029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0073 0.0116 0.0837
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0003 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0075
Trichomonas vaginalis ran, putative 0.0026 0.0025 0.0257
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0057 0.0084 0.6852
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0131 0.0131
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0046 0.0046
Trichomonas vaginalis esterase, putative 0.0072 0.0114 0.1189
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0073 0.0116 0.073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0075
Onchocerca volvulus 0.0058 0.0086 0.0856
Mycobacterium leprae Probable lipase LipE 0.0072 0.0114 0.0439
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0015 0.0005 0.0332
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0042 0.0411
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0073 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0043 0.0311

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.09 um PUBCHEM_BIOASSAY: E3 Ligase dose-response_384. (Class of assay: confirmatory) [Related pubchem assays: 1444 (E3 Ligase_dose response), 1442 (E3 Ligase_dose response), 1230 (E3 Ligase HTS_1536)] ChEMBL. No reference
Potency (functional) 0.2512 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (binding) = 5.0119 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) 5.0119 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.3225 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (binding) 11.2202 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 67.4555 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485342, AID485388] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 100 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 125.8925 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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