Detailed information for compound 1512472

Basic information

Technical information
  • TDR Targets ID: 1512472
  • Name: 2-(2-adamantylcarbamoyl)cyclohexane-1-carboxy lic acid
  • MW: 305.412 | Formula: C18H27NO3
  • H donors: 2 H acceptors: 3 LogP: 3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1CCCCC1C(=O)O)NC1C2CC3CC1CC(C2)C3
  • InChi: 1S/C18H27NO3/c20-17(14-3-1-2-4-15(14)18(21)22)19-16-12-6-10-5-11(8-12)9-13(16)7-10/h10-16H,1-9H2,(H,19,20)(H,21,22)
  • InChiKey: ADYXVQVLTHLZKR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(2-adamantylamino)-oxomethyl]-1-cyclohexanecarboxylic acid
  • 2-[(2-adamantylamino)carbonyl]cyclohexanecarboxylic acid
  • MLS001001081
  • SMR000499114
  • IVK/0016817

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0878 0.2397
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.004 0.01
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0108 0.0279 0.0567
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0386 0.1056
Schistosoma mansoni aldo-keto reductase 0.0253 0.0743 0.0833
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3652 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.006 0.0064
Brugia malayi DKFZp564C0469 protein 0.0027 0.0021 0.003
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0275 0.0272
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0275 0.0744
Plasmodium vivax basic transcription factor 3b, putative 0.0065 0.0141 0.0379
Giardia lamblia Kinase, CMGC MAPK 0.1068 0.3344 0.9155
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0095 0.0253
Brugia malayi CXXC zinc finger family protein 0.0082 0.0196 0.0325
Entamoeba histolytica hypothetical protein 0.0073 0.017 0.0457
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0878 0.2403
Brugia malayi Inositol-1 0.0041 0.0065 0.0104
Echinococcus multilocularis tankyrase 0.0091 0.0226 0.0223
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.0064 0.0069
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.0064 0.0061
Plasmodium falciparum acyl carrier protein 0.01 0.0256 0.0693
Brugia malayi Alcohol dehydrogenase class III 0.0062 0.0133 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Brugia malayi ABC transporter family protein 0.0052 0.0101 0.0165
Echinococcus multilocularis flap endonuclease 1 0.0026 0.002 0.0017
Trichomonas vaginalis DNA helicase recq, putative 0.0065 0.0141 0.0379
Brugia malayi WGR domain containing protein 0.0553 0.17 0.2854
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0027 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0141 0.0379
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Mycobacterium ulcerans polyketide synthase MbtC 0.025 0.0732 0.1538
Plasmodium falciparum histone acetyltransferase GCN5 0.0035 0.0048 0.0124
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0088 0.0217 0.0406
Brugia malayi Tubulin beta-1 chain 0.1165 0.3652 0.6136
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.025 0.0732 0.0821
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0065 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0305 0.0908 0.1718
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0022 0.0032
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.004 0.0041
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0023 0.0062
Echinococcus multilocularis voltage gated potassium channel subunit 0.0073 0.0169 0.0166
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0062 0.0133 0.0253
Entamoeba histolytica hypothetical protein 0.0091 0.0226 0.0611
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.0312 0.0309
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0354 0.0962
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0147 0.0162
Trypanosoma brucei epsilon tubulin 0.064 0.1977 0.5412
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0157 0.0173
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0015 0.0032
Schistosoma mansoni importin beta-1 0.0056 0.0114 0.0125
Onchocerca volvulus 0.0253 0.0743 0.1304
Brugia malayi Heterochromatin protein 1 0.0071 0.0162 0.0267
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0017 0.0006
Trypanosoma brucei RNA helicase, putative 0.0107 0.0276 0.0756
Brugia malayi Fli-1 protein 0.0207 0.0595 0.0995
Schistosoma mansoni hypothetical protein 0.0022 0.0006 0.0003
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0023 0.0054
Loa Loa (eye worm) acyl carrier protein 0.0457 0.1394 0.2642
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0114 0.0303
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0049 0.009 0.0098
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Brugia malayi Cytochrome P450 family protein 0.0038 0.0057 0.0091
Schistosoma mansoni DNA helicase recq1 0.0038 0.0057 0.0061
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.1056 0.3305 0.7057
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0136 0.0368 0.0366
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0227 0.0376
Entamoeba histolytica hypothetical protein 0.0045 0.008 0.0211
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.006 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Loa Loa (eye worm) Smad1 0.0024 0.0013 0.0019
Schistosoma mansoni hypothetical protein 0.0027 0.0023 0.0022
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0013 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Giardia lamblia Gamma tubulin 0.064 0.1977 0.5409
Trypanosoma cruzi importin beta-1 subunit, putative 0.0045 0.008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0002
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0159 0.0297
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0074 0.0203
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0083 0.009
Brugia malayi RNA, U transporter 1 0.0159 0.0442 0.0739
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Onchocerca volvulus Dual oxidase homolog 0.0034 0.0045 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Echinococcus multilocularis tumor protein p63 0.0339 0.1017 0.1014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0073 0.0191
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Loa Loa (eye worm) hypothetical protein 0.0557 0.1713 0.3248
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0065 0.0062
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0065 0.017
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Mycobacterium ulcerans hypothetical protein 0.0027 0.0023 0.0017
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0743 0.1244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0065 0.0119
Echinococcus multilocularis tubulin epsilon chain 0.064 0.1977 0.1974
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.004 0.01
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0073 0.0169 0.0456
Echinococcus granulosus lamin 0.0027 0.0022 0.0021
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2813 0.2811
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.006 0.0156
Brugia malayi jmjC domain containing protein 0.004 0.0064 0.0103
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0908 0.0905
Schistosoma mansoni hypothetical protein 0.0038 0.0057 0.0061
Brugia malayi alpha-tubulin 0.0902 0.2813 0.4725
Loa Loa (eye worm) hypothetical protein 0.0381 0.1152 0.2182
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0239 0.0448
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0095 0.0253
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0036 0.0055
Echinococcus granulosus tubulin subunit TubB 0.0902 0.2813 0.3163
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0169 0.0456
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.004 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0073 0.0191
Loa Loa (eye worm) hypothetical protein 0.0131 0.0352 0.0663
Loa Loa (eye worm) hypothetical protein 0.0066 0.0146 0.0272
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3108 0.6635
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0022 0.0036
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.17 0.465
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.0078 0.0186 0.0347
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0032 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0275 0.0744
Echinococcus multilocularis bloom syndrome protein 0.0065 0.0141 0.0139
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3652 0.4108
Mycobacterium leprae cell division protein FtsZ 0.0278 0.0822 0.1731
Schistosoma mansoni lipoxygenase 0.0116 0.0304 0.0339
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0061 0.0131 0.035
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0163
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0822 0.2244
Loa Loa (eye worm) hypothetical protein 0.012 0.0318 0.0597
Echinococcus granulosus tubulin alpha chain 0.0902 0.2813 0.3163
Echinococcus multilocularis peroxisome assembly protein 26 0.0902 0.2813 0.2811
Schistosoma mansoni topbp1 0.0027 0.0021 0.002
Loa Loa (eye worm) multidrug resistance protein 3 0.0033 0.004 0.0069
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0169 0.0456
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0239 0.0396
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0116
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0133 0.0218
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0062 0.0162
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0037
Echinococcus granulosus tubulin alpha chain 0.0902 0.2813 0.3163
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.0066
Plasmodium falciparum replication factor C subunit 1, putative 0.0027 0.0021 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0259 0.0525
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0032
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0068 0.0153 0.0284
Brugia malayi hypothetical protein 0.0022 0.0004 0.0002
Leishmania major DNA polymerase eta, putative 0.0139 0.0378 0.1029
Entamoeba histolytica tubulin alpha-1 chain 0.0902 0.2813 0.77
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0658 0.2034 0.433
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0754 0.2342 0.2633
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1165 0.3652 0.365
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0049 0.009 0.0087
Entamoeba histolytica tubulin alpha chain, putative 0.0902 0.2813 0.77
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0057 0.0148
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0062 0.0133 0.0253
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0227 0.0252
Echinococcus granulosus tubulin subunit beta 0.1165 0.3652 0.4108
Echinococcus granulosus importin subunit beta 1 0.0056 0.0114 0.0125
Leishmania major p-glycoprotein 0.0033 0.004 0.01
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0065 0.007
Entamoeba histolytica aldose reductase, putative 0.0253 0.0743 0.2027
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.004 0.01
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0065 0.0062
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0108 0.0279 0.0567
Brugia malayi Bromodomain containing protein 0.0035 0.0047 0.0074
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0045 0.0114
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.006 0.0156
Leishmania major hypothetical protein, conserved 0.0058 0.0121 0.0324
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0275 0.0744
Loa Loa (eye worm) blistered cuticle protein 3 0.0034 0.0045 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0065 0.0105
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0074 0.0195
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.1977 0.5409
Trichomonas vaginalis tubulin, putative 0.0362 0.109 0.298
Schistosoma mansoni hypothetical protein 0.0095 0.0239 0.0265
Onchocerca volvulus 0.0027 0.0022 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0171 0.0469
Echinococcus granulosus GA binding protein alpha chain 0.0068 0.0153 0.0168
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Echinococcus multilocularis beta tubulin 0.1165 0.3652 0.365
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0013 0.0011
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.006 0.0156
Trichomonas vaginalis set domain proteins, putative 0.0262 0.0771 0.2106
Echinococcus granulosus tubulin beta 1 chain 0.1165 0.3652 0.4108
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0732 0.1538
Echinococcus granulosus aldehyde reductase 0.018 0.0509 0.0569
Schistosoma mansoni cpg binding protein 0.0082 0.0196 0.0217
Onchocerca volvulus 0.0031 0.0035 0.0051
Entamoeba histolytica hypothetical protein 0.0091 0.0226 0.0611
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0444 0.0497
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.109 0.298
Entamoeba histolytica transcription factor BTF3, putative 0.0065 0.0141 0.0379
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0062 0.0133 0.0253
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.064 0.1977 0.5409
Brugia malayi Ets-domain containing protein 0.0068 0.0153 0.0252
Echinococcus multilocularis nibrin 0.0027 0.0021 0.0018
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Mycobacterium tuberculosis Polyketide synthase Pks13 0.1487 0.4678 1
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0062 0.0133 0.0246
Schistosoma mansoni protein phosphatase 2C 0.004 0.0064 0.0069
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.01 0.0256 0.0518
Brugia malayi Pax transcription activation domain interacting protein 0.0027 0.0021 0.003
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3108 0.6635
Leishmania major prostaglandin f synthase, putative 0.0253 0.0743 0.2027
Trypanosoma brucei beta tubulin 0.1165 0.3652 1
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0354 0.0395
Brugia malayi polk-prov protein 0.008 0.0192 0.0317
Echinococcus granulosus smad 0.0024 0.0013 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0065 0.0105
Mycobacterium ulcerans acyl carrier protein 0.01 0.0256 0.0518
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0381 0.1152 0.2029
Loa Loa (eye worm) tubulin beta-1 chain 0.1165 0.3652 0.693
Loa Loa (eye worm) acetyltransferase 0.0136 0.0368 0.0694
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0381 0.1044
Loa Loa (eye worm) hypothetical protein 0.0205 0.0591 0.1116
Trichomonas vaginalis conserved hypothetical protein 0.03 0.0891 0.2434
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.006 0.0156
Giardia lamblia Histone acetyltransferase GCN5 0.0035 0.0048 0.0124
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0141 0.0386 0.1048
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0065 0.0062
Loa Loa (eye worm) hypothetical protein 0.0071 0.0161 0.0301
Echinococcus multilocularis tubulin beta 1 chain 0.1165 0.3652 0.365
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0065 0.0062
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0064 0.0168
Echinococcus multilocularis aldo keto reductase 0.0253 0.0743 0.074
Onchocerca volvulus Fatty acid synthase homolog 0.1793 0.5655 1
Brugia malayi ABC transporter family protein 0.0033 0.004 0.0061
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0133 0.0355
Echinococcus multilocularis muscleblind protein 0.0305 0.0908 0.0905
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0597 0.1839 0.3486
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0032 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0192 0.0525
Toxoplasma gondii beta tubulin 0.1165 0.3652 1
Brugia malayi Kringle domain containing protein 0.0022 0.0006 0.0005
Onchocerca volvulus 0.0033 0.004 0.0059
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0208 0.0599 0.0671
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0062 0.0133 0.0253
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0239 0.0236
Mycobacterium ulcerans fatty acid synthase Fas 0.0312 0.0932 0.1968
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0036 0.009
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0133 0.0355
Onchocerca volvulus 0.0025 0.0015 0.0015
Onchocerca volvulus 0.0362 0.109 0.192
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0017 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3344 0.9155
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0065 0.007
Mycobacterium leprae conserved hypothetical protein 0.01 0.0256 0.0518
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0354 0.0728
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0354 0.0395
Leishmania major beta tubulin 0.1165 0.3652 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0112 0.0122
Trypanosoma cruzi DNA polymerase eta, putative 0.0139 0.0378 0.1029
Echinococcus granulosus chromobox protein 1 0.0071 0.0162 0.0179
Echinococcus multilocularis aldehyde reductase 0.018 0.0509 0.0506
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0017 0.0006
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Loa Loa (eye worm) hypothetical protein 0.0062 0.0133 0.0246
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.1487 0.4678 1
Leishmania major beta tubulin 0.1165 0.3652 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0239 0.0236
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.025 0.0732 0.1384
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Echinococcus multilocularis tubulin gamma 1 chain 0.064 0.1977 0.1974
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3652 0.365
Plasmodium vivax aldehyde reductase, putative 0.0073 0.0169 0.0456
Leishmania major hypothetical protein, conserved 0.03 0.0891 0.2434
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0275 0.0744
Trypanosoma cruzi ISWI complex protein 0.0028 0.0026 0.0062
Echinococcus granulosus jumonji domain containing protein 0.0038 0.0057 0.0061
Giardia lamblia Beta tubulin 0.1165 0.3652 1
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3652 0.4108
Giardia lamblia Sgs1 DNA helicase, putative 0.0038 0.0057 0.0147
Schistosoma mansoni transcription factor btf3 0.0065 0.0141 0.0156
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0305 0.0908 0.1718
Leishmania major hypothetical protein, conserved 0.004 0.0064 0.0168
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0032 0.0036 0.0037
Entamoeba histolytica hypothetical protein 0.0091 0.0226 0.0611
Echinococcus multilocularis aldo keto reductase 0.0253 0.0743 0.074
Schistosoma mansoni hypothetical protein 0.1164 0.3647 0.4103
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.025 0.0732 0.1226
Schistosoma mansoni DNA polymerase IV / kappa 0.0027 0.0023 0.0022
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Echinococcus granulosus nibrin 0.0027 0.0021 0.002
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0038 0.0057 0.0054
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0021 0.0049
Echinococcus granulosus tubulin gamma 1 chain 0.064 0.1977 0.2222
Mycobacterium tuberculosis Probable oxidoreductase 0.0062 0.0133 0.0253
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Entamoeba histolytica aldose reductase, putative 0.0253 0.0743 0.2027
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0354 0.0728
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0133 0.0355
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2813 0.5336
Schistosoma mansoni inositol monophosphatase 0.0041 0.0065 0.007
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Mycobacterium ulcerans oxidoreductase 0.0062 0.0133 0.0253
Entamoeba histolytica Flap nuclease, putative 0.0026 0.002 0.0046
Echinococcus multilocularis AMP dependent ligase 0.0101 0.0259 0.0256
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0001
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0131 0.0128
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2813 0.5336
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0051 0.0079
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Trichomonas vaginalis ABC transporter, putative 0.0033 0.004 0.01
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0362 0.109 0.298
Schistosoma mansoni smad 0.0024 0.0013 0.0011
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0715 0.2215 0.4718
Plasmodium vivax delta tubulin, putative 0.0278 0.0822 0.2244
Brugia malayi intermediate filament protein 0.0027 0.0022 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0065 0.0105
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0021 0.0057
Mycobacterium ulcerans oxidoreductase 0.0253 0.0743 0.1561
Entamoeba histolytica tubulin family protein 0.1165 0.3652 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0304 0.0339
Trichomonas vaginalis tubulin beta chain, putative 0.0362 0.109 0.298
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0013 0.001
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0017 0.0039
Plasmodium vivax ABC transporter G family member 2, putative 0.0061 0.0131 0.035
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0022
Mycobacterium leprae Polyketide synthase Pks13 0.1487 0.4678 1
Loa Loa (eye worm) histone methyltransferase 0.0026 0.002 0.0032
Toxoplasma gondii acyl carrier protein ACP 0.01 0.0256 0.0693
Loa Loa (eye worm) beta-tubulin 0.1165 0.3652 0.693
Echinococcus granulosus beta tubulin 0.1165 0.3652 0.4108
Echinococcus multilocularis NADH dehydrogenase 0.01 0.0256 0.0253
Chlamydia trachomatis DNA ligase 0.0027 0.0021 0.0046
Echinococcus granulosus replication factor c subunit 1 0.0027 0.0021 0.002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0108 0.0279 0.0567
Entamoeba histolytica acetyltransferase, GNAT family 0.0035 0.0048 0.0124
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.004 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0095 0.0253
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0046 0.0117
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0057 0.0103
Trypanosoma cruzi ABC transporter, putative 0.0061 0.0131 0.035
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0227 0.0252
Toxoplasma gondii beta-tubulin, putative 0.1165 0.3652 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3652 1
Trypanosoma brucei unspecified product 0.0128 0.0344 0.0941
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0108 0.0279 0.0567
Schistosoma mansoni hypothetical protein 0.0107 0.0276 0.0307
Brugia malayi N-terminal motif family protein 0.0381 0.1152 0.1932
Trypanosoma brucei DNA polymerase eta, putative 0.0139 0.0378 0.1036
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Onchocerca volvulus 0.0296 0.0878 0.1544
Trypanosoma brucei DNA polymerase IV, putative 0.0128 0.0344 0.0941
Onchocerca volvulus 0.005 0.0094 0.0155
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0073 0.0078
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Trypanosoma brucei DNA repair protein, putative 0.0058 0.0121 0.0332
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3305 0.7057
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0127 0.0241
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Schistosoma mansoni cpg binding protein 0.009 0.0222 0.0247
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0065 0.0105
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0061 0.0131 0.035
Echinococcus granulosus poly adp ribose polymerase 2 0.0553 0.17 0.191
Loa Loa (eye worm) hypothetical protein 0.0058 0.0121 0.0225
Echinococcus granulosus voltage gated potassium channel subunit 0.0073 0.0169 0.0187
Echinococcus multilocularis hypothetical protein 0.0902 0.2813 0.2811
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0878 0.2397
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0133 0.0355
Plasmodium falciparum tubulin beta chain 0.1165 0.3652 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0033
Giardia lamblia DINP protein human, muc B family 0.0101 0.0259 0.07
Schistosoma mansoni ap endonuclease 0.0039 0.006 0.0064
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.004 0.0037
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0023 0.0054
Leishmania major beta tubulin 0.1165 0.3652 1
Echinococcus granulosus transcription factor btf3 0.0065 0.0141 0.0156
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.0902 0.2813 0.5336
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Echinococcus granulosus chromobox protein 1 0.0071 0.0162 0.0179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.006 0.0156
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2813 0.2811
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Leishmania major beta tubulin 0.1165 0.3652 1
Brugia malayi Phosphopantetheine attachment site family protein 0.01 0.0256 0.0425
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Loa Loa (eye worm) oxidoreductase 0.0253 0.0743 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Trichomonas vaginalis tubulin alpha chain, putative 0.1165 0.3652 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Echinococcus multilocularis tubulin subunit TubB 0.0902 0.2813 0.2811
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Schistosoma mansoni tubulin subunit epsilon 0.064 0.1977 0.2222
Brugia malayi hypothetical protein 0.0073 0.017 0.028
Leishmania major DNA polymerase kappa, putative 0.0027 0.0023 0.0054
Mycobacterium ulcerans polyketide synthase Pks9 0.0658 0.2034 0.433
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0275 0.0516
Trypanosoma brucei ABC transporter, putative 0.0061 0.0131 0.0358
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0159 0.0436
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3344 0.9155
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0065 0.0105
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0133 0.0363
Echinococcus granulosus tankyrase 0.0091 0.0226 0.0251
Loa Loa (eye worm) acyl carrier protein 0.01 0.0256 0.048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0146 0.0161
Entamoeba histolytica hypothetical protein 0.0069 0.0157 0.0421
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0022 0.0036
Onchocerca volvulus DNA ligase 3 homolog 0.0058 0.0121 0.0204
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0017 0.0039
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0065 0.007
Brugia malayi Tubulin beta chain 0.0278 0.0822 0.1377
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0878 0.2397
Schistosoma mansoni hypothetical protein 0.0028 0.0026 0.0025
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0062 0.0133 0.0253
Plasmodium falciparum ABC transporter G family member 2 0.0061 0.0131 0.035
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0021 0.0048
Echinococcus granulosus poly (ADP ribose) polymerase 0.026 0.0765 0.0858
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0068 0.0178
Toxoplasma gondii quinone oxidoreductase, putative 0.0062 0.0133 0.0355
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0057 0.0091
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0048
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.025 0.0732 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0937 0.2923 0.5545
Loa Loa (eye worm) tubulin beta-2A chain 0.1165 0.3652 0.693
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0065 0.007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0386 0.1048
Schistosoma mansoni bromodomain containing protein 0.0125 0.0333 0.0372
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0065 0.017
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0031 0.0036 0.0033
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0073 0.0169 0.0456
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.009
Onchocerca volvulus 0.0082 0.0196 0.0337
Onchocerca volvulus 0.0027 0.0021 0.0026
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0004 0.0001
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2813 0.3163
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.006 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0065 0.0119
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0068 0.0178
Treponema pallidum DNA ligase (lig) 0.0027 0.0021 0.0041
Schistosoma mansoni lipoxygenase 0.0081 0.0193 0.0214
Echinococcus multilocularis geminin 0.0504 0.1542 0.154
Loa Loa (eye worm) hypothetical protein 0.0058 0.0121 0.0224
Echinococcus granulosus tubulin alpha 0.064 0.1977 0.2222
Entamoeba histolytica recQ family helicase, putative 0.0044 0.0074 0.0195
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0063 0.0136 0.0223
Echinococcus granulosus mitogen activated protein kinase 3 0.1068 0.3344 0.3761
Plasmodium vivax replication factor C subunit 1, putative 0.0027 0.0021 0.0049
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0062 0.0133 0.0363
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0386 0.1048
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0159 0.0176
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0732 0.1997
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0027 0.0066
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0114 0.0311
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2813 0.77
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0033
Schistosoma mansoni zinc finger protein 0.0028 0.0026 0.0025
Echinococcus granulosus hypothetical protein 0.0253 0.0743 0.0833
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0063
Onchocerca volvulus 0.0046 0.0083 0.0136
Schistosoma mansoni smad1 5 8 and 0.0024 0.0013 0.0011
Onchocerca volvulus 0.0062 0.0133 0.0224
Loa Loa (eye worm) hypothetical protein 0.005 0.0095 0.0175
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0995 0.3108 0.6635
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0006 0.0008
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0057 0.009
Trypanosoma brucei aldo/keto reductase, putative 0.0073 0.0169 0.0463
Loa Loa (eye worm) hypothetical protein 0.0624 0.1927 0.3653
Mycobacterium ulcerans polyketide synthase Pks13 0.1487 0.4678 1
Schistosoma mansoni hypothetical protein 0.0022 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0186 0.0347
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0057 0.0156
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0004 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0004 0.0002
Echinococcus granulosus peroxisome assembly protein 26 0.0902 0.2813 0.3163
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0083 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0025 0.0061
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0102 0.0189
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0033 0.004 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0095 0.0253
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0063 0.0136 0.1471
Plasmodium falciparum phd finger protein, putative 0.0027 0.0023 0.0054
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Trypanosoma brucei acyl transferase-like protein 0.0063 0.0136 0.0372
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0153 0.0422 0.0874
Echinococcus granulosus geminin 0.0504 0.1542 0.1733
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0021 0.0048
Toxoplasma gondii kringle domain-containing protein 0.0022 0.0006 0.0008
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0008
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0153 0.0422 0.0796
Brugia malayi multidrug resistance protein 3 0.0033 0.004 0.0061
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0133 0.0363
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0033 0.004 0.01
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3652 0.365
Echinococcus multilocularis zinc finger protein 0.0044 0.0076 0.0073
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0095 0.0239 0.0448
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0102
Trypanosoma cruzi beta tubulin, putative 0.1165 0.3652 1
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0275 0.0744
Leishmania major acyl carrier protein, putative 0.01 0.0256 0.0693
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0065 0.0062
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0057 0.009
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0743 0.2027
Brugia malayi glutaminase DH11.1 0.0543 0.1668 0.28
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0023 0.0054
Loa Loa (eye worm) tubulin beta chain 0.1165 0.3652 0.693
Entamoeba histolytica P-glycoprotein-2 0.0033 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Mycobacterium ulcerans DNA polymerase IV 0.0141 0.0386 0.0796
Schistosoma mansoni ets-related 0.0207 0.0595 0.0666
Echinococcus multilocularis poly (ADP ribose) polymerase 0.016 0.0447 0.0444
Leishmania major zeta tubulin, putative 0.0278 0.0822 0.2244
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0065 0.007
Loa Loa (eye worm) PHD-finger family protein 0.0038 0.0057 0.0102
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0073 0.0191
Brugia malayi isocitrate dehydrogenase 0.0032 0.0036 0.0055
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0007 0.0005
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0065 0.017
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0036 0.009
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0033 0.004 0.0069
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0056 0.0114 0.021
Entamoeba histolytica hypothetical protein 0.0091 0.0226 0.0611
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0094 0.0102
Brugia malayi ImpB/MucB/SamB family protein 0.0088 0.0217 0.0359
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0253 0.0743 0.1561
Giardia lamblia Beta tubulin 0.1165 0.3652 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2813 0.2811
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.004 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0065 0.0105
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0019
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0275 0.0516
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0062 0.0133 0.1431
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.01 0.0256 0.0518
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0133 0.0253
Echinococcus multilocularis lamin 0.0027 0.0022 0.0019
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0065 0.007
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0159 0.0428
Mycobacterium tuberculosis Conserved protein 0.0073 0.0169 0.0332
Plasmodium vivax tubulin gamma chain, putative 0.064 0.1977 0.5409
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0624 0.1927 0.5271
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0964 0.3011 0.6426
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0275 0.0744
Echinococcus granulosus phd:f box containing protein 0.004 0.0064 0.0069
Brugia malayi PHD-finger family protein 0.0054 0.0107 0.0175
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.1927 0.3653
Mycobacterium tuberculosis Probable oxidoreductase 0.0253 0.0743 0.1561
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Brugia malayi Blistered cuticle protein 3 0.0034 0.0045 0.007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0147 0.0144
Leishmania major zinc binding dehydrogenase-like protein 0.0062 0.0133 0.0355
Mycobacterium ulcerans quinone reductase Qor 0.0062 0.0133 0.0253
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.0113
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.1977 0.5409
Leishmania major basic transcription factor 3a, putative 0.0065 0.0141 0.0379
Trichomonas vaginalis taga, putative 0.0033 0.004 0.01
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0239 0.0265
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0038 0.0057 0.0061
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0021 0.0048
Onchocerca volvulus Huntingtin homolog 0.012 0.0318 0.0552
Loa Loa (eye worm) transcription factor SMAD2 0.0356 0.1072 0.203
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0059 0.0124 0.0331
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Plasmodium falciparum alpha tubulin 1 0.0902 0.2813 0.77
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0065 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0192 0.0525
Loa Loa (eye worm) glutaminase 0.0543 0.1668 0.3162
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0033
Leishmania major DNA polymerase kappa, putative 0.0101 0.0259 0.07
Brugia malayi MH2 domain containing protein 0.0024 0.0013 0.0017
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0591 0.0988
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0171 0.0469
Schistosoma mansoni hypothetical protein 0.0504 0.1542 0.1733
Trypanosoma brucei epsilon tubulin 0.064 0.1977 0.5412
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0141 0.0379
Loa Loa (eye worm) ICD-1 protein 0.0065 0.0141 0.0263
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.006 0.0098
Loa Loa (eye worm) CXXC zinc finger family protein 0.0082 0.0196 0.0367
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3108 0.6635
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Schistosoma mansoni alpha tubulin 0.0902 0.2813 0.3163
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0023 0.0054
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0065 0.0062
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3652 0.365
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.0136 0.0149
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0027 0.012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0004 0.0001
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2813 0.2811
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.004 0.0041
Trypanosoma brucei alpha tubulin, putative 0.0362 0.109 0.2986
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0354 0.0962
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.002 0.0046
Echinococcus granulosus snurportin 1 0.0597 0.1839 0.2067
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0062 0.0133 0.0253
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0033 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0036 0.0037
Trichomonas vaginalis tubulin, putative 0.1165 0.3652 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0004 0.0001
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.0064 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1068 0.3344 0.9156
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0065 0.0119
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.109 0.298
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0127 0.0241
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.002 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0021 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0036 0.0033
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Echinococcus granulosus microtubule associated protein 2 0.2806 0.8885 1
Entamoeba histolytica hypothetical protein 0.0073 0.017 0.0457
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0354 0.0728
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0754 0.2342 0.6409
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0061 0.0131 0.0144
Leishmania major beta tubulin 0.1165 0.3652 1
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0065 0.0105
Onchocerca volvulus Alhambra homolog 0.0027 0.0023 0.003
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3652 0.4108
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0004 0.0003
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0061 0.0131 0.035
Toxoplasma gondii exonuclease III APE 0.0039 0.006 0.0156
Echinococcus granulosus aldo keto reductase 0.0253 0.0743 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0048
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.0066
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2813 0.5336
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.004 0.01
Leishmania major cytochrome p450-like protein 0.0038 0.0057 0.0148
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2813 0.2811
Trypanosoma cruzi tubulin gamma chain 0.064 0.1977 0.5409
Giardia lamblia Aldose reductase 0.0253 0.0743 0.2027
Schistosoma mansoni multidrug resistance protein 0.0033 0.004 0.0041
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0065 0.007
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.0894 0.1498
Loa Loa (eye worm) jmjC domain-containing protein 0.016 0.0444 0.0838
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0045 0.0114
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0645 0.1994 0.5456
Echinococcus multilocularis dnaJ subfamily C 6 0.0062 0.0134 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0048
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.004 0.0037
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0743 0.2027
Echinococcus multilocularis musashi 0.0027 0.0022 0.0019
Leishmania major DNA polymerase eta, putative 0.0078 0.0185 0.0498
Brugia malayi Tnks protein 0.0091 0.0226 0.0375
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Brugia malayi jmjC domain containing protein 0.004 0.0064 0.0103
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.01 0.0256 0.0253
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.017 0.0188
Schistosoma mansoni ABC transporter 0.0052 0.0101 0.011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0065 0.007
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.004 0.0037
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0062 0.0133 0.0253
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0004 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Brugia malayi MAP kinase sur-1 0.1068 0.3344 0.5618
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0065 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0065 0.0119
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.17 0.465
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0813 0.253 0.5395
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2813 0.3163
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0023 0.0054
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0131 0.0144
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0062 0.0133 0.0253
Mycobacterium ulcerans cell division protein FtsZ 0.0278 0.0822 0.1731
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.006 0.053
Leishmania major hypothetical protein, conserved 0.0028 0.0026 0.0062
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0073 0.0169 0.0187
Mycobacterium leprae Probable polyketide synthase Pks1 0.1056 0.3305 0.7057
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0065 0.007
Brugia malayi Pre-SET motif family protein 0.0035 0.0046 0.0072
Chlamydia trachomatis acyl carrier protein 0.01 0.0256 0.3339
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0057 0.0103
Leishmania major beta tubulin 0.1165 0.3652 1
Echinococcus multilocularis tissue type plasminogen activator 0.0022 0.0006 0.0003
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2813 0.77
Mycobacterium leprae Conserved hypothetical protein 0.018 0.0509 0.106
Brugia malayi WGR domain containing protein 0.0754 0.2342 0.3933
Schistosoma mansoni smad1 5 8 and 0.0024 0.0013 0.0011
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0937 0.2923 0.6238
Brugia malayi jmjC domain containing protein 0.004 0.0064 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0065 0.0119
Trypanosoma brucei unspecified product 0.0061 0.0129 0.0354
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0074 0.0195
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0083 0.009
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0121 0.0324
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0162 0.0302
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0312 0.0932 0.1968
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Giardia lamblia Beta tubulin 0.1165 0.3652 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Loa Loa (eye worm) tubulin beta-4 chain 0.1165 0.3652 0.693
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0027 0.0021 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Entamoeba histolytica zinc finger protein, putative 0.0091 0.0226 0.0611
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0227 0.0224
Brugia malayi steroid hormone receptor 0.0041 0.0065 0.0105
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0009 0.0006
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0153 0.0422 0.0874
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0048
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0027 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0002
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2813 0.77
Schistosoma mansoni blooms syndrome DNA helicase 0.0045 0.008 0.0086
Trichomonas vaginalis tubulin beta chain, putative 0.1165 0.3652 1
Loa Loa (eye worm) hypothetical protein 0.0296 0.0878 0.1662
Echinococcus granulosus alpha tubulin 0.0902 0.2813 0.3163
Loa Loa (eye worm) hypothetical protein 0.03 0.0894 0.1692
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0127 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0141 0.0379
Toxoplasma gondii type I fatty acid synthase, putative 0.0708 0.2194 0.6004
Mycobacterium ulcerans DNA polymerase IV 0.0141 0.0386 0.0796
Echinococcus granulosus Smad4 0.0024 0.0013 0.0011
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0153 0.0422 0.0874
Echinococcus multilocularis dnaJ subfamily B 0.1164 0.3647 0.3645
Plasmodium falciparum alpha tubulin 2 0.0902 0.2813 0.77
Onchocerca volvulus 0.0253 0.0743 0.1304
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0038 0.0057 0.0054
Trypanosoma brucei ISWI complex protein 0.0028 0.0026 0.007
Trypanosoma brucei beta tubulin 0.1165 0.3652 1
Leishmania major oxidoreductase-like protein 0.0062 0.0133 0.0355
Schistosoma mansoni hypothetical protein 0.0597 0.1839 0.2067
Echinococcus multilocularis replication factor c subunit 1 0.0027 0.0021 0.0018
Echinococcus granulosus muscleblind protein 0.0305 0.0908 0.1019
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0062 0.0133 0.0253
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0995 0.3108 0.5222
Loa Loa (eye worm) hypothetical protein 0.008 0.0192 0.0358
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0162 0.0435
Echinococcus multilocularis tubulin delta chain 0.0278 0.0822 0.0819
Brugia malayi hypothetical protein 0.005 0.0095 0.0155
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2813 0.3163
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.0066
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0021 0.0048
Trichomonas vaginalis DNA helicase recq1, putative 0.0065 0.0141 0.0379
Giardia lamblia Replication factor C, subunit 1 0.0027 0.0021 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0065 0.007
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0015 0.0032
Giardia lamblia DNA damage repair protein 0.0027 0.0023 0.0054
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0003 0.0008
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0354 0.0395
Brugia malayi beta-NAC-like protein 0.0065 0.0141 0.0233
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0101 0.0259 0.0525
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3305 0.7057
Schistosoma mansoni coup transcription factor 0.0041 0.0065 0.007
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.0064 0.0069
Toxoplasma gondii type I fatty acid synthase, putative 0.1057 0.3309 0.9059
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1068 0.3344 0.6344
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0062 0.0133 0.0253
Schistosoma mansoni alpha tubulin 0.0902 0.2813 0.3163
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Echinococcus multilocularis GA binding protein alpha chain 0.0068 0.0153 0.015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.0671 0.1268
Trypanosoma brucei zeta tubulin, putative 0.0278 0.0822 0.225
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0108 0.0279 0.0567
Onchocerca volvulus 0.0062 0.0133 0.0224
Loa Loa (eye worm) tubulin alpha 2 0.0262 0.0772 0.146
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.054 0.1658 0.4535
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0004 0.0001
Mycobacterium leprae Probable oxidireductase 0.0062 0.0133 0.0253
Mycobacterium ulcerans hypothetical protein 0.0073 0.0169 0.0332
Trichomonas vaginalis abcb9, putative 0.0033 0.004 0.01
Entamoeba histolytica hypothetical protein 0.0026 0.0017 0.0039
Brugia malayi hypothetical protein 0.0027 0.0021 0.003
Brugia malayi nuclear receptor NHR-88 0.0041 0.0065 0.0105
Loa Loa (eye worm) hypothetical protein 0.0062 0.0133 0.0246
Trypanosoma cruzi tubulin delta chain 0.0278 0.0822 0.2244
Echinococcus granulosus aldo keto reductase 0.0253 0.0743 0.0833
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0036 0.0046
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.017 0.0188
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.008 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0822 0.2244
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.006 0.0156
Brugia malayi Muscleblind-like protein 0.0305 0.0908 0.1521
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0275 0.0558
Leishmania major beta tubulin 0.1165 0.3652 1
Leishmania major zinc-binding dehydrogenase-like protein 0.0062 0.0133 0.0355
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0065 0.017
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0062 0.0133 0.0253
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2813 0.2811
Entamoeba histolytica hypothetical protein 0.0027 0.0021 0.0048
Echinococcus multilocularis phd:f box containing protein 0.004 0.0064 0.0061
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0275 0.0752
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0108 0.0279 0.0567
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0278 0.0822 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0444 0.0497
Trypanosoma brucei epsilon tubulin 0.064 0.1977 0.5412
Loa Loa (eye worm) oxidoreductase 0.0253 0.0743 0.1405
Brugia malayi Methyltransferase-like protein 4 0.03 0.0891 0.1494
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0133 0.0355
Brugia malayi Importin beta-1 subunit 0.0056 0.0114 0.0186
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0065 0.0062
Loa Loa (eye worm) hypothetical protein 0.0139 0.0378 0.0713
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.0064 0.0168
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0112 0.0122
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2813 0.3163
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.025 0.0732 0.1997
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.009
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0073 0.0169 0.0316
Trichomonas vaginalis importin beta-1, putative 0.0045 0.008 0.0211
Schistosoma mansoni hypothetical protein 0.0504 0.1542 0.1733
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2813 0.3163
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Giardia lamblia ABC transporter 0.006 0.0127 0.034
Plasmodium vivax SET domain protein, putative 0.0035 0.0046 0.0117
Loa Loa (eye worm) hypothetical protein 0.0063 0.0136 0.0252
Toxoplasma gondii beta-1 tubulin, putative 0.1165 0.3652 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0057 0.0148
Plasmodium falciparum aldo-keto reductase, putative 0.0073 0.0169 0.0456
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2813 0.3163
Mycobacterium tuberculosis Probable thioesterase TesA 0.0829 0.2579 0.55
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0033 0.004 0.031
Trichomonas vaginalis ABC transporter, putative 0.0033 0.004 0.01
Entamoeba histolytica P-glyco protein 6, putative 0.0033 0.004 0.01
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0038 0.0057 0.0061
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0036 0.0098
Plasmodium falciparum importin beta, putative 0.0056 0.0114 0.0303
Echinococcus multilocularis Smad4 0.0024 0.0013 0.001
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0159 0.0263
Toxoplasma gondii hypothetical protein 0.0048 0.0087 0.0231
Echinococcus granulosus tubulin alpha chain 0.0902 0.2813 0.3163
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2813 0.2811
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Echinococcus multilocularis aldo keto reductase 0.0253 0.0743 0.074
Giardia lamblia PHD finger protein 15 0.0027 0.0023 0.0054
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.0185 0.0498
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0131 0.0144
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0133 0.0355
Plasmodium falciparum basic transcription factor 3b, putative 0.0065 0.0141 0.0379
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.017 0.0167
Trypanosoma cruzi ISWI complex protein 0.0028 0.0026 0.0062
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0062 0.0133 0.0253
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Brugia malayi jmjC domain containing protein 0.004 0.0064 0.0103
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0169 0.0456
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0116
Leishmania major oxidoreductase, putative 0.0062 0.0133 0.0355
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.01 0.0256 0.0701
Toxoplasma gondii aldo-keto reductase 0.0073 0.0169 0.0456
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.002 0.0046
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Brugia malayi 6-phosphofructokinase 0.0107 0.0278 0.0462
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0121 0.0332
Schistosoma mansoni hypothetical protein 0.0062 0.0134 0.0147
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.002 0.0046
Schistosoma mansoni chromosome transmission fidelity factor 0.0027 0.0021 0.002
Schistosoma mansoni glutaminase 0.0543 0.1668 0.1875
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0243 0.0711 0.1493
Schistosoma mansoni multidrug resistance protein 0.0033 0.004 0.0041
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0045 0.0122
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2813 0.2811
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0027 0.0021 0.0013
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0101 0.0259 0.07
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0064 0.0116
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0063 0.0136 0.0364
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0127 0.0139
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0964 0.3011 0.6426
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0131 0.0249
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.002 0.0046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.0894 0.1498
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.1927 0.3653
Brugia malayi Protein kinase domain containing protein 0.0022 0.0006 0.0005
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0062 0.0133 0.0355
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0162 0.0435
Onchocerca volvulus Putative alcohol dehydrogenase 0.0062 0.0133 0.0224
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0013 0.0011
Leishmania major hypothetical protein, conserved 0.005 0.0095 0.0253
Trypanosoma cruzi aldo-keto reductase 0.0253 0.0743 0.2027
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0017 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0065 0.0105
Onchocerca volvulus Huntingtin homolog 0.012 0.0318 0.0552
Plasmodium falciparum tubulin epsilon chain, putative 0.064 0.1977 0.5409
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0065 0.0105
Echinococcus multilocularis transcription factor btf3 0.0065 0.0141 0.0138
Leishmania major aldo-keto reductase-like protein 0.0253 0.0743 0.2027
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2813 0.2811
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0007 0.0004
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0059 0.0094
Echinococcus granulosus beta tubulin 0.1165 0.3652 0.4108
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2813 0.3163
Loa Loa (eye worm) oxidoreductase 0.0253 0.0743 0.1405
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.004 0.0041
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0136 0.0368 0.0411
Schistosoma mansoni microtubule-associated protein tau 0.2806 0.8885 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0065 0.007
Schistosoma mansoni hypothetical protein 0.0095 0.0239 0.0265
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.01 0.0256 0.0425
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0065 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Trypanosoma brucei tubulin delta chain 0.0278 0.0822 0.225
Schistosoma mansoni hypothetical protein 0.0051 0.0098 0.0107
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0065 0.007
Trypanosoma brucei chrX additional, unordered contigs 0.0027 0.0023 0.0062
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.025 0.0732 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0822 0.2244
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0335 0.091
Plasmodium vivax importin-beta 2, putative 0.0056 0.0114 0.0303
Mycobacterium ulcerans polyketide synthase 0.0995 0.3108 0.6635
Leishmania major quinone oxidoreductase, putative 0.0062 0.0133 0.0355
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0023 0.0054
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0033 0.004 0.01
Mycobacterium tuberculosis Hypothetical protein 0.03 0.0891 0.188
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0995 0.3108 0.6635
Plasmodium falciparum tubulin delta chain, putative 0.0278 0.0822 0.2244
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0069
Leishmania major beta tubulin 0.1165 0.3652 1
Echinococcus multilocularis dna polymerase eta 0.0139 0.0378 0.0376
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0051 0.0098 0.0178
Schistosoma mansoni chromobox protein 0.0071 0.0162 0.0179
Leishmania major gamma-tubulin 0.064 0.1977 0.5409
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Onchocerca volvulus 0.0262 0.0771 0.1355
Brugia malayi Tubulin alpha chain 0.0278 0.0822 0.1377
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.1056 0.3305 0.7057
Echinococcus granulosus poly (ADP ribose) polymerase 0.0191 0.0544 0.0609
Schistosoma mansoni DNA helicase recq5 0.0038 0.0057 0.0061
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0133 0.0355
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0127 0.0124
Echinococcus granulosus tubulin alpha chain 0.0902 0.2813 0.3163
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0063 0.0136 0.1656
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0021 0.0049
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.008 0.0211
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0027 0.0066
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0159 0.0428
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0065 0.007
Onchocerca volvulus 0.0027 0.0022 0.0028
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0133 0.013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Schistosoma mansoni tubulin subunit alpha 0.0278 0.0822 0.0922
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.109 0.298
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0027 0.0021 0.0049
Trypanosoma brucei prostaglandin f synthase 0.0253 0.0743 0.2033
Echinococcus granulosus flap endonuclease 1 0.0026 0.002 0.0019
Echinococcus granulosus jumonji domain containing 1A 0.004 0.0064 0.0069
Brugia malayi Bloom's syndrome protein homolog 0.0065 0.0141 0.0233
Echinococcus multilocularis tubulin subunit beta 0.1165 0.3652 0.365
Trypanosoma brucei unspecified product 0.0061 0.0129 0.0354
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0062 0.0133 0.0253
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0036 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Entamoeba histolytica tubulin family protein 0.1165 0.3652 1
Schistosoma mansoni lamin 0.0027 0.0022 0.0021
Leishmania major beta tubulin 0.1165 0.3652 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0208 0.0599 0.0596
Brugia malayi PHD-finger family protein 0.0027 0.0023 0.0033
Plasmodium falciparum cysteine repeat modular protein 1 0.0022 0.0006 0.0008
Schistosoma mansoni smdr2 0.0033 0.004 0.0041
Echinococcus granulosus intermediate filament protein 0.0027 0.0022 0.0021
Echinococcus granulosus mitogen activated protein kinase 0.1068 0.3344 0.3761
Echinococcus multilocularis cpg binding protein 0.009 0.0222 0.0219
Loa Loa (eye worm) hypothetical protein 0.0091 0.0227 0.0425
Loa Loa (eye worm) hypothetical protein 0.0149 0.0411 0.0775
Leishmania major epsilon tubulin, putative 0.064 0.1977 0.5409
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0386 0.1056
Trypanosoma cruzi acyl transferase-like protein, putative 0.0063 0.0136 0.0364
Loa Loa (eye worm) TK/ROR protein kinase 0.0022 0.0006 0.0006
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.004 0.0041
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0062 0.0133 0.0253
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.005 0.0089
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0127 0.0208
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.0023 0.0038
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0362 0.1092 0.2067
Brugia malayi chromobox protein homolog 3 0.004 0.0062 0.01
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Schistosoma mansoni tankyrase 0.0091 0.0226 0.0251
Trypanosoma brucei alpha tubulin 0.0902 0.2813 0.7702
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.0064 0.0168
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0169 0.0456
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0065 0.0062
Brugia malayi phosphofructokinase 0.0106 0.0275 0.0457
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0108 0.0279 0.0567
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.002 0.0054
Mycobacterium ulcerans glutaminase 0.0543 0.1668 0.3546
Schistosoma mansoni potassium channel beta 0.0073 0.0169 0.0187
Leishmania major beta tubulin 0.1165 0.3652 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0114 0.0311
Trypanosoma brucei beta tubulin 0.1165 0.3652 1
Brugia malayi MH2 domain containing protein 0.0356 0.1072 0.1798
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0754 0.2342 0.2339
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0027 0.0066
Schistosoma mansoni methyltransferase-related 0.03 0.0891 0.1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Echinococcus granulosus tubulin beta 4A class IVa 0.1165 0.3652 0.4108
Loa Loa (eye worm) ABC transporter 0.0052 0.0101 0.0186
Loa Loa (eye worm) tubulin alpha-3 chain 0.054 0.1658 0.3143
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3108 0.6635
Onchocerca volvulus 0.0091 0.0227 0.0391
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.0136 0.0149
Trichomonas vaginalis tubulin alpha chain, putative 0.064 0.1977 0.5409
Leishmania major delta tubulin, putative 0.0278 0.0822 0.2244
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0153 0.0422 0.0874
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0743 0.0833
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Trypanosoma brucei alpha tubulin 0.0902 0.2813 0.7702
Giardia lamblia Aldose reductase 0.0253 0.0743 0.2027
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0275 0.0744
Toxoplasma gondii alpha tubulin TUBA1 0.0902 0.2813 0.77
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3344 0.9155
Entamoeba histolytica ABC transporter, putative 0.0061 0.0131 0.035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0022
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0097 0.0257
Echinococcus multilocularis aldo keto reductase 0.0253 0.0743 0.074
Giardia lamblia Alpha-tubulin 0.0902 0.2813 0.77
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0116 0.0215
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0073 0.0191
Brugia malayi acetyltransferase, GNAT family protein 0.0136 0.0368 0.0614
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.0064 0.0069
Schistosoma mansoni alpha tubulin 0.0902 0.2813 0.3163
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0304 0.0301
Trypanosoma brucei poly(adp-ribose) polymerase 0.0553 0.17 0.4655
Plasmodium vivax hypothetical protein, conserved 0.015 0.0415 0.1128
Brugia malayi jmjC domain containing protein 0.0208 0.0599 0.1002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0013 0.001
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0013 0.0019
Treponema pallidum acyl carrier protein 0.01 0.0256 0.2966
Trichomonas vaginalis tubulin epsilon chain, putative 0.0278 0.0822 0.2244
Mycobacterium tuberculosis Conserved protein 0.03 0.0891 0.188
Leishmania major beta tubulin 0.1165 0.3652 1
Trypanosoma brucei beta tubulin 0.1165 0.3652 1
Schistosoma mansoni inositol monophosphatase 0.0041 0.0065 0.007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0057 0.0147
Loa Loa (eye worm) DnaJ domain-containing protein 0.0062 0.0134 0.0248
Leishmania major DNA damage repair protein, putative 0.0027 0.0023 0.0054
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Leishmania major beta tubulin 0.1165 0.3652 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0108 0.0279 0.0464
Schistosoma mansoni hypothetical protein 0.0095 0.0239 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0062 0.0133 0.0253
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0159 0.0176
Loa Loa (eye worm) oxidoreductase 0.0253 0.0743 0.1405
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0061
Loa Loa (eye worm) oxidoreductase 0.0253 0.0743 0.1405
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0065 0.017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0164 0.0457 0.1245
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0072 0.0117
Leishmania major d-xylulose reductase, putative 0.0062 0.0133 0.0355
Entamoeba histolytica P-glycoprotein-1 0.0033 0.004 0.01
Trichomonas vaginalis replication factor C large subunit, putative 0.0027 0.0021 0.0049
Giardia lamblia Methyltransferase like 2 0.03 0.0891 0.2434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0046 0.0048
Echinococcus granulosus NADH dehydrogenase 0.01 0.0256 0.0285
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.025 0.0732 0.1997
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0253 0.0743 0.1405
Plasmodium vivax DNA repair protein REV1, putative 0.0027 0.0023 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0025 0.0061
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.006 0.053
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0072 0.0189
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0061 0.0131 0.035
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2813 0.3163
Entamoeba histolytica hypothetical protein 0.0073 0.017 0.0457
Schistosoma mansoni acyl carrier protein 0.01 0.0256 0.0285
Giardia lamblia Epsilon tubulin 0.0278 0.0822 0.2244
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0133 0.0355
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0088 0.0217 0.0214
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0275 0.0558
Onchocerca volvulus 0.0073 0.0169 0.0289
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0088 0.0217 0.024
Brugia malayi tubulin alpha-2 chain 0.0902 0.2813 0.4725
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0065 0.007
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0114 0.0111
Mycobacterium ulcerans hypothetical protein 0.01 0.0256 0.0518
Entamoeba histolytica P-glycoprotein-2 0.0033 0.004 0.01
Mycobacterium tuberculosis Cell division protein FtsZ 0.0278 0.0822 0.1731
Mycobacterium ulcerans oxidoreductase FadB5 0.0062 0.0133 0.0253
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0062 0.0133 0.0355
Mycobacterium ulcerans polyketide synthase MbtD 0.0306 0.0911 0.1922
Onchocerca volvulus 0.0253 0.0743 0.1304
Schistosoma mansoni hypothetical protein 0.0073 0.017 0.0188
Echinococcus multilocularis GPCR, family 2 0.0095 0.0239 0.0236
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0275 0.0306
Schistosoma mansoni jumonji domain containing protein 0.019 0.054 0.0605
Schistosoma mansoni tubulin subunit delta 0.0278 0.0822 0.0922
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0822 0.2244
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0127 0.0339
Brugia malayi hypothetical protein 0.0032 0.0039 0.006
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0027 0.0021 0.0041
Trypanosoma brucei tubulin gamma chain 0.064 0.1977 0.5412
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0023 0.0054
Leishmania major beta tubulin 0.1165 0.3652 1
Brugia malayi hypothetical protein 0.012 0.0318 0.0529
Plasmodium vivax multidrug resistance protein 1, putative 0.0033 0.004 0.01
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0065 0.0105
Loa Loa (eye worm) hypothetical protein 0.012 0.0318 0.0597
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0088 0.0217 0.024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0065 0.0119
Loa Loa (eye worm) hypothetical protein 0.1672 0.5269 1
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0275 0.0306
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0062 0.0133 0.0253
Trypanosoma cruzi alpha tubulin, putative 0.0902 0.2813 0.77
Schistosoma mansoni terminal deoxycytidyl transferase 0.0088 0.0217 0.024
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.1056 0.3305 0.7057
Echinococcus multilocularis lysine specific demethylase 5A 0.0151 0.0418 0.0415
Echinococcus multilocularis chromobox protein 1 0.0071 0.0162 0.0159
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0038 0.0057 0.0102
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0133 0.0253
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3652 0.365
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.01 0.0256 0.0518
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0565 0.1739 0.3699
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0062 0.0133 0.0253
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.025 0.0732 0.8882
Trichomonas vaginalis ABC transporter, putative 0.0033 0.004 0.01
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0073 0.0169 0.0456
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.006 0.0098
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.006 0.0156
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0046 0.0043
Brugia malayi hypothetical protein 0.0027 0.0021 0.003
Echinococcus granulosus AMP dependent ligase 0.0101 0.0259 0.0288
Trypanosoma brucei transcription factor BTF3, putative 0.0065 0.0141 0.0387
Mycobacterium ulcerans thioesterase TesA 0.0829 0.2579 0.55
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.08 0.2488 0.5305
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0312 0.0932 0.1968
Plasmodium vivax JmjC domain containing protein 0.004 0.0064 0.0168
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2813 0.3163
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0036 0.0037
Brugia malayi Smad1 0.0024 0.0013 0.0017
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0159 0.0428
Trypanosoma cruzi FHA domain containing protein, putative 0.0027 0.0021 0.0048
Echinococcus granulosus methyl CpG binding domain protein 2 0.0031 0.0036 0.0037
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0133 0.0355
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0732 0.1997
Echinococcus multilocularis peregrin 0.0035 0.0047 0.0044
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0169 0.0456
Trichomonas vaginalis ABC transporter, putative 0.0033 0.004 0.01
Schistosoma mansoni smad1 5 8 and 0.0024 0.0013 0.0011
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.0064 0.0168
Schistosoma mansoni jumonji domain containing protein 0.004 0.0064 0.0069
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0036 0.009
Entamoeba histolytica P-glycoprotein-5 0.0033 0.004 0.01
Entamoeba histolytica deoxycytidyl transferase, putative 0.0088 0.0217 0.0585
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.004 0.0037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0112 0.0183
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0354 0.0351
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0065 0.007
Echinococcus multilocularis dna polymerase kappa 0.0141 0.0386 0.0383
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0073 0.0169 0.028
Echinococcus granulosus dna polymerase eta 0.0139 0.0378 0.0423
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.002 0.0032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0064 0.0168
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0065 0.0178
Mycobacterium ulcerans polyketide synthase 0.1056 0.3305 0.7057
Leishmania major hypothetical protein, conserved 0.0063 0.0136 0.0364
Giardia lamblia Delta tubulin 0.0278 0.0822 0.2244
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2813 0.3163
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0624 0.1927 0.3653
Leishmania major beta tubulin 0.1165 0.3652 1
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0275 0.0744
Trichomonas vaginalis abcb9, putative 0.0033 0.004 0.01
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1068 0.3344 0.9155
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.025 0.0732 0.1997
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.006 0.0108
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.01 0.0256 0.048
Loa Loa (eye worm) MH2 domain-containing protein 0.0356 0.1072 0.203
Echinococcus granulosus bloom syndrome protein 0.0065 0.0141 0.0156
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0169 0.0456
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Mycobacterium ulcerans hypothetical protein 0.0156 0.0432 0.0895
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0002
Echinococcus granulosus lamin dm0 0.0027 0.0022 0.0021
Loa Loa (eye worm) inositol-1 0.0041 0.0065 0.0117
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0036
Schistosoma mansoni flap endonuclease-1 0.0024 0.0012 0.001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3344 0.9155
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0343 0.0382
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0017 0.0039
Echinococcus multilocularis ATP binding cassette sub family B 0.0032 0.0036 0.0033
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0743 0.2027
Loa Loa (eye worm) tnks protein 0.0091 0.0226 0.0423
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.004 0.01
Schistosoma mansoni tubulin subunit beta 0.0278 0.0822 0.0922
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.0146 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0019
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0108 0.0279 0.0567
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0153 0.0422 0.0874
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2813 0.5336
Echinococcus multilocularis smad 0.0024 0.0013 0.001
Leishmania major beta tubulin 0.1165 0.3652 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0057 0.0147
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3652 0.693
Plasmodium falciparum aldehyde reductase, putative 0.0073 0.0169 0.0456
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0342 0.1026 0.2169
Loa Loa (eye worm) tubulin gamma chain 0.064 0.1977 0.3748
Entamoeba histolytica P-glycoprotein 5, putative 0.0033 0.004 0.01
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0141 0.0379
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0023 0.0054
Brugia malayi nuclear receptor RXR 0.0022 0.0004 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0023 0.0062
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.025 0.0732 0.2004
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0038 0.0057 0.0147
Schistosoma mansoni multidrug resistance protein 0.0033 0.004 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0259 0.0708
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0112 0.0122
Schistosoma mansoni phd/f-box containing protein 0.004 0.0064 0.0069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0112 0.0206
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0065 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0068 0.0178
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.004 0.0037
Trypanosoma brucei alpha tubulin 0.0902 0.2813 0.7702
Echinococcus granulosus tumor protein p63 0.0339 0.1017 0.1142
Toxoplasma gondii alpha-tubulin I, putative 0.0902 0.2813 0.77
Echinococcus multilocularis microtubule associated protein 2 0.2806 0.8885 0.8885
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.002 0.0046
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3652 0.4108
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.08 0.2488 0.5305
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0822 0.2244
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1885 0.5949 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0009 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.0256 0.0518
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0036 0.0033
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0829 0.2579 0.55
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0065 0.007
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0743 0.2027
Schistosoma mansoni DNA ligase IV 0.0027 0.0021 0.002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0051 0.0079
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Trichomonas vaginalis DNA polymerase eta, putative 0.0141 0.0386 0.1048
Entamoeba histolytica P-glycoprotein-2, putative 0.0033 0.004 0.01
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.0098
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0033
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0381 0.1037
Trichomonas vaginalis tubulin, putative 0.0278 0.0822 0.2244
Mycobacterium leprae Possible oxidoreductase 0.0073 0.0169 0.0332
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0275 0.0558
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0108 0.0279 0.0567
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2813 0.77
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0072 0.0189
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.002 0.0017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0112 0.0109
Brugia malayi 6-phosphofructokinase 0.0106 0.0275 0.0457
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.004 0.0064 0.0168
Trypanosoma brucei alpha tubulin 0.0902 0.2813 0.7702
Plasmodium falciparum flap endonuclease 1 0.0026 0.002 0.0046
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0073 0.0169 0.0456
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0381 0.1037
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0133 0.0146
Echinococcus granulosus tubulin epsilon chain 0.064 0.1977 0.2222
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0065 0.0062
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.004 0.0065 0.0169
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Schistosoma mansoni tubulin subunit gamma 0.064 0.1977 0.2222
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0023 0.0062
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.0064 0.0061
Onchocerca volvulus Tankyrase homolog 0.0091 0.0226 0.0389
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0112 0.0122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0088 0.0217 0.0433
Echinococcus granulosus acyl carrier protein mitochondrial 0.01 0.0256 0.0285
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0065 0.007
Loa Loa (eye worm) tubulin beta chain 0.0278 0.0822 0.1555
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0133 0.0218
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0131 0.0249
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0462 0.1409 0.1583
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0658 0.2034 0.433
Entamoeba histolytica hypothetical protein 0.0065 0.0141 0.0379
Echinococcus multilocularis lamin dm0 0.0027 0.0022 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0065 0.0105
Echinococcus multilocularis chromobox protein 1 0.0071 0.0162 0.0159
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.004 0.0037
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2813 0.4725
Schistosoma mansoni phosphatidylserine receptor 0.004 0.0064 0.0069
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0995 0.3108 0.6635
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0073 0.0169 0.0456
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.0136 0.0149
Brugia malayi tubulin alpha chain - mouse 0.0902 0.2813 0.4725
Schistosoma mansoni zinc finger protein 0.0044 0.0076 0.0082
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.004 0.0041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.006 0.0164
Brugia malayi ecdysteroid receptor 0.0041 0.0065 0.0105
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0009 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0175 0.0492 0.0551
Brugia malayi Ets-domain containing protein 0.0068 0.0153 0.0252
Mycobacterium ulcerans acyl carrier protein 0.01 0.0256 0.0518
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0065 0.0105
Echinococcus granulosus tubulin delta chain 0.0278 0.0822 0.0922
Schistosoma mansoni zinc binding dehydrogenase 0.0062 0.0133 0.0146
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.0023 0.0022
Treponema pallidum cell division protein FtsZ 0.0278 0.0822 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0743 0.2027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.0066
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0064 0.0116
Loa Loa (eye worm) hypothetical protein 0.0062 0.0133 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.1068 0.3344 0.3761
Schistosoma mansoni intermediate filament proteins 0.0027 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.1977 0.5409
Mycobacterium ulcerans oxidoreductase 0.0062 0.0133 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0163
Echinococcus multilocularis beta tubulin 0.1165 0.3652 0.365
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0402 0.1218 0.2582
Brugia malayi Bromodomain containing protein 0.0074 0.0171 0.0283
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Echinococcus granulosus dna polymerase kappa 0.0141 0.0386 0.0431
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0062 0.0133 0.0253
Schistosoma mansoni pol-related 0.0253 0.0743 0.0833
Loa Loa (eye worm) fli-1 protein 0.0207 0.0595 0.1124
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0022
Echinococcus granulosus zinc finger protein 0.0044 0.0076 0.0082
Loa Loa (eye worm) hypothetical protein 0.0553 0.17 0.3222
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0062 0.0133 0.0253
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0386 0.1048
Loa Loa (eye worm) fatty acid synthase 0.0981 0.3066 0.5817
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0743 0.1244
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0743 0.1244
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0902 0.2813 0.77
Trichomonas vaginalis tubulin gamma chain, putative 0.1165 0.3652 1
Leishmania major beta tubulin 0.1165 0.3652 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.0259 0.0702
Toxoplasma gondii acyl transferase domain-containing protein 0.0063 0.0136 0.0364
Brugia malayi MH1 domain containing protein 0.0024 0.0013 0.0017
Brugia malayi Pre-SET motif family protein 0.023 0.0671 0.1123
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3344 0.9155
Trypanosoma cruzi aldo/keto reductase, putative 0.0073 0.0169 0.0456
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.01 0.0256 0.2966
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0119
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0133 0.0355
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.006 0.0057
Plasmodium falciparum DNA repair protein REV1, putative 0.0027 0.0023 0.0054
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0259 0.0525
Loa Loa (eye worm) hypothetical protein 0.0153 0.0422 0.0796
Trichomonas vaginalis abcb9, putative 0.0033 0.004 0.01
Echinococcus granulosus peregrin 0.0035 0.0047 0.005
Schistosoma mansoni gabp alpha 0.0068 0.0153 0.0168
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0743 0.2027
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.004 0.01
Plasmodium vivax tubulin beta chain, putative 0.1165 0.3652 1
Trichomonas vaginalis glutaminase, putative 0.0543 0.1668 0.4563
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0743 0.1244
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3108 0.6635
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.002 0.0019
Onchocerca volvulus 0.0115 0.0304 0.0527
Echinococcus multilocularis tubulin alpha 0.064 0.1977 0.1974
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0131 0.0144
Loa Loa (eye worm) hypothetical protein 0.0087 0.0212 0.0396
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0068 0.0186
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0065 0.0119
Brugia malayi Cytochrome P450 family protein 0.0038 0.0057 0.0091
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0278 0.0822 0.2244
Onchocerca volvulus 0.0937 0.2923 0.5164
Entamoeba histolytica aldose reductase, putative 0.0253 0.0743 0.2027
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0065 0.017
Plasmodium falciparum tubulin gamma chain 0.064 0.1977 0.5409
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0275 0.3197
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0146 0.0161
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1068 0.3344 0.9155
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0095 0.0253
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0063 0.0136 0.0364
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1068 0.3344 0.9155
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1068 0.3344 0.9155
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0141 0.0379
Echinococcus granulosus WGR domain containing protein 0.026 0.0765 0.0858
Trypanosoma brucei protein kinase, putative 0.1068 0.3344 0.9156
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0069
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0239 0.0265
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2813 0.77
Brugia malayi ImpB/MucB/SamB family protein 0.0139 0.0378 0.0631
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0017 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0095 0.0261
Entamoeba histolytica tubulin gamma chain 0.064 0.1977 0.5409
Brugia malayi jmjC domain containing protein 0.016 0.0444 0.0742
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0239 0.0396
Toxoplasma gondii aldose reductase, putative 0.0253 0.0743 0.2027
Schistosoma mansoni cpg binding protein 0.009 0.0222 0.0247
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0159 0.0428
Onchocerca volvulus 0.0253 0.0743 0.1304
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0732 0.1538
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Schistosoma mansoni Smad4 0.0024 0.0013 0.0011
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.01 0.0256 0.0693
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0038
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.015 0.0415 0.1128
Schistosoma mansoni chromobox protein 0.0071 0.0162 0.0179
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0074 0.0195
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.004 0.01
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0036 0.009
Schistosoma mansoni aldo-keto reductase 0.0253 0.0743 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Brugia malayi Tubulin gamma chain 0.064 0.1977 0.3319
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.0136 0.0149
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Mycobacterium tuberculosis Polyketide synthase Pks12 0.1056 0.3305 0.7057
Echinococcus multilocularis mitogen activated protein kinase 0.1068 0.3344 0.3342
Schistosoma mansoni ap endonuclease 0.0039 0.006 0.0064
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0036 0.009
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0822 0.2244
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0226 0.0611
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.1977 0.5409
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0017 0.0048
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3652 0.693
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0133 0.0253
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0131 0.0128
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1068 0.3344 0.9155
Loa Loa (eye worm) hypothetical protein 0.0062 0.0133 0.0246
Echinococcus granulosus dnaJ subfamily B 0.1164 0.3647 0.4103
Trichomonas vaginalis tubulin, putative 0.0362 0.109 0.298
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3652 0.365
Brugia malayi DnaJ domain containing protein 0.0062 0.0134 0.022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.004 0.01
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0743 0.074
Brugia malayi Tubulin alpha chain 0.0902 0.2813 0.4725
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0062 0.0133 0.0253
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Toxoplasma gondii type I fatty acid synthase 0.0153 0.0422 0.1149
Trypanosoma cruzi tubulin delta chain 0.0278 0.0822 0.2244
Brugia malayi AMP-binding enzyme family protein 0.0307 0.0914 0.1532
Schistosoma mansoni DNA polymerase eta 0.0139 0.0378 0.0423
Loa Loa (eye worm) glutaminase 2 0.0543 0.1668 0.3162
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0275 0.0306
Schistosoma mansoni lamin 0.0027 0.0022 0.0021
Trypanosoma brucei aldo-keto reductase, putative 0.0253 0.0743 0.2033
Onchocerca volvulus 0.0253 0.0743 0.1304
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0504 0.1542 0.4218
Brugia malayi topoisomerase 0.0027 0.0021 0.003
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0033 0.004 0.01
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0133 0.0253
Loa Loa (eye worm) tubulin alpha-2 chain 0.0902 0.2813 0.5336
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0065 0.007
Brugia malayi nuclear hormone receptor 0.0041 0.0065 0.0105
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0065 0.017
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0133 0.0253
Leishmania major ferric reductase, putative 0.0034 0.0045 0.0114
Loa Loa (eye worm) hypothetical protein 0.0461 0.1406 0.2665
Echinococcus granulosus poly ADP ribose polymerase 1 0.0754 0.2342 0.2633
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.0146 0.0143
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0159 0.0156
Leishmania major beta tubulin 0.1165 0.3652 1
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.01 0.0256 0.0443
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0101 0.0259 0.0523
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0432 0.0895
Brugia malayi MH1 domain containing protein 0.0024 0.0013 0.0017
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0131 0.0249
Leishmania major nuclear receptor binding factor-like protein 0.0062 0.0133 0.0355
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.0064 0.0176
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0065 0.017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0001
Mycobacterium ulcerans dehydrogenase 0.0062 0.0133 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0065 0.0105
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0004 0.0002
Toxoplasma gondii ATPase, AAA family protein 0.0027 0.0021 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0386 0.1056
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0065 0.0105
Brugia malayi Bromodomain containing protein 0.0146 0.0402 0.0672
Schistosoma mansoni hypothetical protein 0.0205 0.0591 0.0662
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0065 0.0105
Trypanosoma cruzi acyl transferase-like protein 0.0063 0.0136 0.0364
Plasmodium vivax tubulin epsilon chain, putative 0.064 0.1977 0.5409
Schistosoma mansoni hypothetical protein 0.01 0.0256 0.0285
Trypanosoma brucei beta tubulin 0.064 0.1977 0.5412
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0306 0.0911 0.1922
Brugia malayi Flap endonuclease-1 0.0026 0.002 0.0028
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0743 0.2027
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0275 0.0744
Onchocerca volvulus 0.0253 0.0743 0.1304
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0065 0.007
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0553 0.17 0.191
Onchocerca volvulus 0.0041 0.0065 0.0105
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.025 0.0732 0.0821
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0171 0.0469
Brugia malayi MH2 domain containing protein 0.0024 0.0013 0.0017
Leishmania major importin beta-1 subunit, putative 0.0045 0.008 0.0211
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0112 0.0109
Schistosoma mansoni tubulin subunit beta 0.1165 0.3652 0.4108
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0073 0.0191
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3652 0.4108
Trypanosoma brucei zeta tubulin 0.0278 0.0822 0.225
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0063 0.0136 0.026
Leishmania major beta tubulin 0.1165 0.3652 1
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0101 0.0259 0.0525
Brugia malayi hypothetical protein 0.0296 0.0878 0.1472
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0133 0.0218
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0095 0.0253
Trypanosoma cruzi aldo/keto reductase, putative 0.0253 0.0743 0.2027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0112 0.0122
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.0023 0.002
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0131 0.0128
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0065 0.0105
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0781 0.2427 0.6642
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.0894 0.1692
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0064 0.0116
Brugia malayi beta-tubulin, identical 0.1165 0.3652 0.6136
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.0312 0.0348
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2813 0.4725
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0034
Giardia lamblia Alpha-tubulin 0.0902 0.2813 0.77
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0354 0.0728
Brugia malayi hypothetical protein 0.0022 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0095 0.0239 0.0265
Plasmodium falciparum multidrug resistance protein 1 0.0033 0.004 0.01
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.08 0.2488 0.5305
Loa Loa (eye worm) hypothetical protein 0.005 0.0094 0.0172
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0013 0.0019
Mycobacterium ulcerans thioesterase 0.0829 0.2579 0.55
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0127 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0003
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0027 0.0021 0.003
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0275 0.0516
Echinococcus multilocularis snurportin 1 0.0597 0.1839 0.1836
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0017 0.0006
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0157 0.0173
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.025 0.0732 0.1997
Toxoplasma gondii NAC domain-containing protein 0.0065 0.0141 0.0379
Onchocerca volvulus 0.1739 0.5481 0.9692
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2813 0.2811
Brugia malayi Cell division protein ftsZ 0.0278 0.0822 0.1377
Leishmania major DNA repair protein, putative 0.0058 0.0121 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0032 0.0078
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0995 0.3108 0.6635
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0062 0.01
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0065 0.0591
Mycobacterium ulcerans short-chain dehydrogenase 0.0069 0.0157 0.0305
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0553 0.17 0.1697
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0027 0.0066
Trichomonas vaginalis protein kinase inhibitor, putative 0.0062 0.0134 0.0358
Trichomonas vaginalis tubulin gamma chain, putative 0.0278 0.0822 0.2244
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2813 0.2811
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0133 0.0253
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.0185 0.0498
Echinococcus granulosus GPCR family 2 0.0095 0.0239 0.0265
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0065 0.0108
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.006 0.0156
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2813 0.2811
Trypanosoma brucei ATP-binding cassette protein, putative 0.0061 0.0131 0.0358
Echinococcus granulosus cpg binding protein 0.009 0.0222 0.0247
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.0032
Entamoeba histolytica hypothetical protein 0.0073 0.017 0.0457
Echinococcus granulosus tissue type plasminogen activator 0.0022 0.0006 0.0003
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0253 0.0743 0.2027
Leishmania major alpha tubulin 0.0902 0.2813 0.77
Trypanosoma cruzi DNA repair protein, putative 0.0058 0.0121 0.0324
Echinococcus granulosus tubulin alpha chain 0.0902 0.2813 0.3163
Mycobacterium ulcerans acyl-CoA synthetase 0.0108 0.0279 0.0567
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0022 0.0006 0.0008
Schistosoma mansoni alcohol dehydrogenase 0.0062 0.0133 0.0146
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.1056 0.3305 0.7057
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0253 0.0743 0.2027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3344 0.9155
Echinococcus granulosus dnaJ subfamily C 6 0.0062 0.0134 0.0147
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0023 0.0062
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.0023 0.0022
Plasmodium vivax acyl carrier protein, putative 0.01 0.0256 0.0693
Brugia malayi NADH-dependent xylose reductase 0.0073 0.0169 0.028
Loa Loa (eye worm) hypothetical protein 0.054 0.1658 0.3143
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0135
Echinococcus multilocularis mitogen activated protein kinase 3 0.1068 0.3344 0.3342
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0065 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0066
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0036 0.0037
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0057 0.0103
Echinococcus granulosus aldo keto reductase 0.0253 0.0743 0.0833
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0083 0.009
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.0057 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0065 0.0105
Brugia malayi Tubulin beta chain 0.0362 0.109 0.1829
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0386 0.1048
Brugia malayi AMP-binding enzyme family protein 0.0937 0.2923 0.4911
Schistosoma mansoni topbp1 0.0027 0.0021 0.002
Echinococcus granulosus lysine specific demethylase 5A 0.016 0.0444 0.0497
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0065 0.0119
Loa Loa (eye worm) RecQ helicase 0.0065 0.0141 0.0263

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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