Detailed information for compound 29501

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 381.422 | Formula: C22H23NO5
  • H donors: 2 H acceptors: 5 LogP: 3.08 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)[C@@H](CCC(=O)N1C(Cc2c1cccc2)C(=O)O)CCc1ccccc1
  • InChi: 1S/C22H23NO5/c24-20(23-18-9-5-4-8-17(18)14-19(23)22(27)28)13-12-16(21(25)26)11-10-15-6-2-1-3-7-15/h1-9,16,19H,10-14H2,(H,25,26)(H,27,28)/t16-,19?/m1/s1
  • InChiKey: YDLSLXIGMPNXTQ-VTBWFHPJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Oryctolagus cuniculus Angiotensin-converting enzyme Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Angiotensin-converting enzyme family protein Get druggable targets OG5_131988 All targets in OG5_131988
Loa Loa (eye worm) angiotensin-converting enzyme family protein Get druggable targets OG5_131988 All targets in OG5_131988
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.000006738
Mycobacterium ulcerans DNA polymerase IV 0.008 0.0341 0.1092
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0142 0.1821
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0011 0.0141
Onchocerca volvulus 0.0019 0.0011 0.0014
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0401 0.0401
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0162 0.0775 1
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0011 0.0148
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.007 0.0894
Schistosoma mansoni polycystin 1-related 0.0315 0.1597 0.1597
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0011 0.0068
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0011 0.0088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0002 0.0006
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0113 0.0515 0.6648
Leishmania major cytochrome p450-like protein 0.0018 0.0004 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0337 0.0336
Brugia malayi nuclear hormone receptor family member nhr-6 0.0071 0.0291 0.0366
Brugia malayi hypothetical protein 0.011 0.0499 0.0629
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0171 0.2207
Onchocerca volvulus 0.0032 0.0084 0.0108
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0011 0.0141
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0023 0.0023
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0162 0.0775 0.0977
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Schistosoma mansoni caspase-7 (C14 family) 0.0083 0.0357 0.0356
Schistosoma mansoni tyrosine kinase 0.0021 0.0023 0.0023
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0136 0.0848
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Onchocerca volvulus 0.0047 0.0161 0.0206
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0332 0.0332
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0348 0.1771 0.5686
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0059
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0011 0.0141
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0121 0.0121
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0011 0.0035
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0023 0.0023
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0291 0.0366
Loa Loa (eye worm) nuclear hormone receptor 0.0071 0.0291 0.0366
Echinococcus multilocularis neuropeptide s receptor 0.0495 0.2559 0.2559
Treponema pallidum sodium- and chloride- dependent transporter 0.1466 0.7756 1
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0248
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0034 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0341 0.4392
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0153 0.0562
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0407 0.0406
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0136 0.0848
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0011 0.0011
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0001 0.0000085038
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0151 0.0717 0.0717
Echinococcus multilocularis caspase 3 0.0071 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0249 0.1242 0.1242
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0011 0.0014
Brugia malayi jmjC domain containing protein 0.0093 0.0407 0.0512
Echinococcus granulosus nuclear receptor nhr 48 0.0071 0.0291 0.029
Loa Loa (eye worm) matrixin family protein 0.0041 0.0132 0.0166
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0094 0.0118
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0148 0.0186
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.008 0.0337 0.0336
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0011 0.0011
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0083 0.0357 0.045
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.000006738
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0305 0.0304
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Echinococcus multilocularis caspase 8 0.0043 0.0142 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0034 0.0042
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0196 0.0246
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0291 0.029
Onchocerca volvulus Protein ultraspiracle homolog 0.0151 0.0717 0.0924
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0059
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Schistosoma mansoni nuclear receptor nhr-48 0.0071 0.0291 0.029
Trypanosoma brucei unspecified product 0.0067 0.0271 0.3499
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0136 0.0848
Plasmodium vivax SET domain protein, putative 0.0032 0.0081 0.0506
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.000006738
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0047 0.0161 0.0202
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0004 0.0012
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0105 0.0132
Leishmania major short chain dehydrogenase, putative 0.0019 0.0011 0.0141
Brugia malayi Steroid receptor seven-up type 2 0.0151 0.0717 0.0904
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0068 0.0273 0.0273
Echinococcus granulosus bloom syndrome protein 0.0023 0.0033 0.0032
Entamoeba histolytica hypothetical protein 0.0074 0.0306 0.3947
Onchocerca volvulus 0.0315 0.1597 0.2058
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0136 0.0135
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0116 0.1495
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0075 0.0312 0.2508
Echinococcus granulosus RUN 0.0315 0.1597 0.1597
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Entamoeba histolytica aldose reductase, putative 0.0162 0.0775 1
Echinococcus granulosus dna polymerase kappa 0.008 0.0341 0.034
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0238 0.1911
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.01 0.0446 0.1432
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0075 0.0312 0.0393
Mycobacterium ulcerans oxidoreductase 0.0019 0.0011 0.0035
Schistosoma mansoni RAR-like nuclear receptor 0.0151 0.0717 0.0717
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0033 0.0118
Echinococcus multilocularis lipoxygenase domain containing protein 0.0315 0.1597 0.1597
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0118 0.0117
Giardia lamblia Short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Onchocerca volvulus 0.0071 0.0291 0.0374
Loa Loa (eye worm) hypothetical protein 0.1466 0.7756 0.9789
Loa Loa (eye worm) cysteine protease 0.0032 0.0084 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0081 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0118 0.0431
Onchocerca volvulus 0.0249 0.1242 0.1601
Onchocerca volvulus 0.0019 0.0011 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0148 0.0147
Mycobacterium ulcerans dehydrogenase 0.0042 0.0136 0.0435
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0004 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0249 0.1242 0.1242
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.008 0.0341 0.1251
Echinococcus multilocularis FTZ F1 alpha 0.0151 0.0717 0.0717
Brugia malayi Protein kinase domain containing protein 0.0021 0.0023 0.0028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0306 0.0305
Brugia malayi NADH-dependent xylose reductase 0.0047 0.0161 0.0202
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0033 0.0032
Brugia malayi Doublecortin family protein 0.0315 0.1597 0.2015
Onchocerca volvulus 0.0071 0.0291 0.0374
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0125 0.0579 0.0579
Mycobacterium tuberculosis Probable oxidoreductase 0.0162 0.0775 0.2681
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.000006738
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Leishmania major cathepsin L-like protease 0.0032 0.0084 0.1079
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0071 0.0291 0.029
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Onchocerca volvulus 0.0075 0.0312 0.0402
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0011 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Echinococcus granulosus thyroid hormone receptor alpha 0.0071 0.0291 0.029
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0205 0.0257
Brugia malayi Nuclear hormone receptor-like 1 0.0151 0.0717 0.0904
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0011 0.0011
Echinococcus granulosus tyrosine protein kinase Srms 0.0021 0.0023 0.0023
Trypanosoma cruzi DNA polymerase eta, putative 0.0028 0.0062 0.0793
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Onchocerca volvulus 0.0026 0.0048 0.0061
Loa Loa (eye worm) oxidoreductase 0.0162 0.0775 0.0977
Echinococcus multilocularis dna polymerase kappa 0.008 0.0341 0.034
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0011 0.0038
Brugia malayi Hemopexin family protein 0.0026 0.0052 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Brugia malayi secreted modular calcium-binding protein 1 0.0075 0.0312 0.0393
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0011 0.0035
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0084 0.0105
Brugia malayi orphan nuclear receptor NR2E1 0.0071 0.0291 0.0366
Onchocerca volvulus 0.0042 0.0136 0.0174
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0011 0.0038
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0011 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0097 0.0431 0.5559
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0004 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0148
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0028 0.0062 0.0061
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0071 0.0291 0.0366
Trichomonas vaginalis glutaminase, putative 0.0266 0.1331 0.4896
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0136 0.0135
Brugia malayi Protein kinase domain containing protein 0.0021 0.0023 0.0028
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0011 0.0148
Brugia malayi hypothetical protein 0.008 0.0337 0.0424
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0075 0.0074
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.1242 0.1567
Brugia malayi Pre-SET motif family protein 0.0223 0.1102 0.1391
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Brugia malayi polk-prov protein 0.0061 0.0236 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0084 0.1078
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0004 0.0011
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0054 0.0199 0.025
Brugia malayi hypothetical protein 0.0315 0.1597 0.2015
Trypanosoma cruzi aldo/keto reductase, putative 0.0047 0.0161 0.2068
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0084 0.1078
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0011 0.0088
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0011 0.0141
Onchocerca volvulus 0.011 0.0499 0.0642
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0249 0.1242 0.1567
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0249 0.1242 1
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Entamoeba histolytica aldose reductase, putative 0.0162 0.0775 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Loa Loa (eye worm) DR-78 0.0071 0.0291 0.0366
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0049 0.0173 0.2228
Echinococcus granulosus hypothetical protein 0.0019 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0118 0.0117
Schistosoma mansoni survival motor neuron protein 0.0052 0.0187 0.0186
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0027 0.0026
Trypanosoma brucei metacaspase MCA2 0.0043 0.0142 0.1821
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Trypanosoma brucei metacaspase 5, putative 0.0043 0.0142 0.1821
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Trypanosoma brucei unspecified product 0.002 0.0015 0.0185
Schistosoma mansoni hypothetical protein 0.0052 0.0187 0.0186
Brugia malayi Matrixin family protein 0.0045 0.0152 0.0191
Trypanosoma brucei DNA polymerase eta, putative 0.0028 0.0062 0.0793
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0011 0.0141
Giardia lamblia Kinase, PLK 0.0092 0.0401 0.5175
Brugia malayi tailless protein 0.0071 0.0291 0.0366
Echinococcus granulosus tyrosine kinase 0.0021 0.0023 0.0023
Trypanosoma brucei prostaglandin f synthase 0.0162 0.0775 1
Schistosoma mansoni hypothetical protein 0.0074 0.0306 0.0305
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0004 0.0012
Leishmania major cathepsin L-like protease 0.0124 0.0573 0.739
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0011 0.0011
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0034 0.0106
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0011 0.0035
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Schistosoma mansoni tyrosine kinase 0.0021 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0062 0.0061
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0162 0.0775 0.2848
Onchocerca volvulus 0.0162 0.0775 0.0998
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0028
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0205 0.0257
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0044 0.0146 0.0466
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0075 0.0312 0.2508
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0000085038
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0011 0.0038
Echinococcus multilocularis neuropeptide receptor A26 0.0495 0.2559 0.2559
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0011 0.0038
Giardia lamblia PHD finger protein 15 0.0028 0.0062 0.0791
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Onchocerca volvulus 0.0032 0.0084 0.0108
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0249 0.1242 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0032 0.0084 0.0084
Echinococcus granulosus hypothetical protein 0.0019 0.0011 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0401 0.0401
Echinococcus granulosus agrin 0.0075 0.0312 0.0311
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0249 0.1242 0.1567
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0291 0.029
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0136 0.109
Brugia malayi Cytochrome P450 family protein 0.0036 0.0103 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0081 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0151 0.0717 0.0904
Brugia malayi hypothetical protein 0.0018 0.0005 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Onchocerca volvulus 0.0162 0.0775 0.0998
Loa Loa (eye worm) hypothetical protein 0.0055 0.0205 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0023 0.0023
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0162 0.0775 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0717 0.0717
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0116 0.0116
Brugia malayi bHLH-PAS transcription factor 0.0073 0.0303 0.0382
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0054 0.0199 0.025
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0114 0.0522 0.0521
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0094 0.0093
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0011 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0126 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0004 0.0012
Brugia malayi nuclear receptor NHR-88 0.0151 0.0717 0.0904
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0151 0.0717 0.0904
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Leishmania major DNA polymerase eta, putative 0.0028 0.0062 0.0793
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Echinococcus multilocularis RUN 0.0315 0.1597 0.1597
Mycobacterium leprae Possible oxidoreductase 0.0047 0.0161 0.2032
Onchocerca volvulus Cathepsin L homolog 0.0032 0.0084 0.0108
Echinococcus multilocularis cysteine protease 0.0032 0.0084 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0011 0.0011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0196 0.0246
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0011 0.0068
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0401 0.5175
Toxoplasma gondii exonuclease III APE 0.0038 0.0116 0.0932
Brugia malayi ecdysteroid receptor 0.0151 0.0717 0.0904
Onchocerca volvulus 0.0032 0.0084 0.0108
Echinococcus multilocularis cathepsin L cysteine protease 0.0032 0.0084 0.0084
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0142 0.0883
Schistosoma mansoni hypothetical protein 0.0026 0.0052 0.0051
Plasmodium falciparum LCCL domain-containing protein 0.0315 0.1597 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.000006738
Plasmodium falciparum metacaspase-like protein 0.0043 0.0142 0.0883
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0236 0.3041
Mycobacterium ulcerans glutaminase 0.0266 0.1331 0.4274
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0249 0.1242 0.1242
Onchocerca volvulus Protein cycle homolog 0.0054 0.0199 0.0255
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.0142 0.0178
Schistosoma mansoni caspase-7 (C14 family) 0.0114 0.0522 0.0521
Schistosoma mansoni follistatin 0.0075 0.0312 0.0311
Onchocerca volvulus 0.0162 0.0775 0.0998
Brugia malayi nuclear receptor RXR 0.008 0.0337 0.0424
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0047 0.0161 0.2068
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0011 0.0011
Toxoplasma gondii hypothetical protein 0.0249 0.1242 1
Loa Loa (eye worm) sodium-independent organic anion transporter 0.011 0.0499 0.0629
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0075 0.0312 0.0393
Mycobacterium ulcerans putative regulatory protein 0.0073 0.0303 0.0972
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Schistosoma mansoni aldo-keto reductase 0.0162 0.0775 0.0774
Loa Loa (eye worm) oxidoreductase 0.0162 0.0775 0.0977
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0047 0.0161 0.0202
Loa Loa (eye worm) RecQ helicase 0.0023 0.0033 0.004
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0023 0.0032 0.004
Onchocerca volvulus 0.011 0.0499 0.0642
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0136 0.0135
Loa Loa (eye worm) dehydrogenase 0.0019 0.0011 0.0014
Brugia malayi Cytochrome P450 family protein 0.0044 0.0146 0.0183
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Schistosoma mansoni amine oxidase 0.0042 0.0136 0.0135
Leishmania major protein kinase, putative 0.0049 0.0173 0.2228
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0034 0.0042
Echinococcus granulosus tyrosine protein kinase Lyn 0.0021 0.0025 0.0024
Onchocerca volvulus 0.0021 0.0023 0.0029
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0011 0.0011
Loa Loa (eye worm) SRC-1 0.0021 0.0023 0.0028
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Echinococcus granulosus aldehyde reductase 0.0115 0.0524 0.0524
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0162 0.0775 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Schistosoma mansoni hypothetical protein 0.0348 0.1771 0.177
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0022 0.0026 0.0209
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0094 0.0093
Brugia malayi hypothetical protein 0.0315 0.1597 0.2015
Plasmodium vivax small ubiquitin-related modifier, putative 0.003 0.007 0.0433
Onchocerca volvulus 0.0032 0.0081 0.0104
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0116 0.0725
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0148 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0151 0.0717 0.0904
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0032 0.0084 0.0084
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0247 0.1234 0.3963
Echinococcus granulosus Small ubiquitin modifier 2 0.003 0.007 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Brugia malayi hypothetical protein 0.0071 0.0291 0.0366
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Schistosoma mansoni tyrosine kinase 0.0701 0.3663 0.3663
Brugia malayi hypothetical protein 0.004 0.0126 0.0158
Schistosoma mansoni cathepsin F (C01 family) 0.0032 0.0084 0.0084
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0011 0.0014
Onchocerca volvulus 0.0162 0.0775 0.0998
Leishmania major DNA polymerase kappa, putative 0.0041 0.0131 0.1686
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.1242 0.1567
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Schistosoma mansoni intermediate filament proteins 0.0055 0.0205 0.0204
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0071
Echinococcus multilocularis musashi 0.0055 0.0205 0.0204
Echinococcus granulosus tyrosine kinase 0.0021 0.0023 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0315 0.1597 0.1597
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0021 0.0023 0.0023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0717 0.0717
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus caspase 0.0114 0.0522 0.0521
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.000006738
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0247 0.1234 0.3963
Echinococcus multilocularis follistatin 0.0075 0.0312 0.0311
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0011 0.0141
Trichomonas vaginalis aldo-keto reductase, putative 0.0047 0.0161 0.0589
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0125 0.0579 0.1859
Loa Loa (eye worm) oxidoreductase 0.0162 0.0775 0.0977
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0062 0.0077
Brugia malayi PAS domain containing protein 0.0122 0.0564 0.0712
Leishmania major pteridine reductase 1 0.0019 0.0011 0.0141
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.0573 0.739
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0136 0.0848
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Trypanosoma cruzi MFS transporter, putative 0.011 0.0499 0.6435
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.0062 0.0213
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0034 0.0106
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1466 0.7756 0.7756
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0004 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Echinococcus multilocularis cysteine protease 0.0032 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.0032 0.0084 0.1079
Echinococcus multilocularis microtubule associated protein 2 0.0674 0.3517 0.3517
Giardia lamblia Sentrin 0.003 0.007 0.0894
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0054 0.0199 0.025
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0028 0.0062 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0146 0.0183
Plasmodium falciparum transporter, putative 0.0249 0.1242 0.7777
Echinococcus multilocularis ecdysone induced protein 78C 0.0151 0.0717 0.0717
Trypanosoma brucei DNA polymerase IV, putative 0.008 0.0341 0.4392
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0004 0.0011
Schistosoma mansoni carbonyl reductase 0.0019 0.0011 0.0011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0151 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0049 0.0171 0.0216
Onchocerca volvulus 0.011 0.0499 0.0642
Echinococcus granulosus oxidoreductase 0.0019 0.0011 0.0011
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0023 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0028 0.0062 0.0061
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0011 0.0014
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0011 0.0088
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0118 0.0431
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Onchocerca volvulus 0.0032 0.0084 0.0108
Echinococcus multilocularis Solute carrier organic anion transporter family 0.011 0.0499 0.0498
Onchocerca volvulus 0.0026 0.0052 0.0066
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0306 0.0305
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0081 0.0081
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0151 0.0717 0.0717
Echinococcus granulosus caspase 3 0.0071 0.029 0.029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0151 0.0717 0.0904
Onchocerca volvulus 0.0032 0.0084 0.0108
Onchocerca volvulus Putative organic anion transporter 0.011 0.0499 0.0642
Mycobacterium ulcerans dehydrogenase 0.0019 0.0011 0.0035
Echinococcus granulosus lamin 0.0055 0.0205 0.0204
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0011 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0151 0.0717 0.0717
Entamoeba histolytica cysteine protease, putative 0.0032 0.0084 0.1086
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0075 0.0312 0.0393
Loa Loa (eye worm) oxidoreductase 0.0162 0.0775 0.0977
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0525 0.2719 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Loa Loa (eye worm) matrix metalloproteinase 0.0019 0.001 0.0012
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0021 0.0023 0.0023
Schistosoma mansoni cytochrome P450 0.0018 0.0004 0.0004
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0151 0.0717 0.0904
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0034 0.0106
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0004 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0004 0.0012
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0136 0.0435
Onchocerca volvulus 0.0019 0.0011 0.0014
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0332 0.0332
Trichomonas vaginalis set domain proteins, putative 0.0254 0.1267 0.466
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0116 0.1495
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0057 0.0352
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0057 0.0352
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0011 0.0011
Trypanosoma brucei aldo/keto reductase, putative 0.0047 0.0161 0.2068
Trypanosoma brucei cytochrome P450, putative 0.0044 0.0146 0.1872
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0238 0.0762
Brugia malayi Cathepsin L-like precursor 0.0022 0.0027 0.0033
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0023 0.0023
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0148 0.0147
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0131 0.1686
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0011 0.0141
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0717 0.0717
Onchocerca volvulus Alhambra homolog 0.0028 0.0062 0.0079
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0088
Schistosoma mansoni retinoic acid receptor RXR 0.0151 0.0717 0.0717
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Onchocerca volvulus 0.0019 0.0011 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Entamoeba histolytica aldose reductase, putative 0.0162 0.0775 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0717 0.0904
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0011 0.0148
Echinococcus granulosus follistatin 0.0075 0.0312 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0011 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0096
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0049 0.0171 0.1376
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0136 0.1748
Onchocerca volvulus 0.0021 0.0023 0.0029
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0047 0.0161 0.1289
Echinococcus multilocularis lipoxygenase domain containing protein 0.0315 0.1597 0.1597
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0151 0.0717 0.0717
Echinococcus multilocularis aldo keto reductase 0.0162 0.0775 0.0774
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0162 0.0775 0.0977
Trypanosoma cruzi metacaspase, putative 0.0043 0.0142 0.1821
Onchocerca volvulus 0.0019 0.0011 0.0014
Loa Loa (eye worm) SMO-1 protein 0.003 0.007 0.0087
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Onchocerca volvulus 0.0315 0.1597 0.2058
Echinococcus multilocularis aldo keto reductase 0.0162 0.0775 0.0774
Brugia malayi hypothetical protein 0.0071 0.0291 0.0366
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0011 0.0141
Echinococcus multilocularis agrin 0.0075 0.0312 0.0311
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0088
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0021 0.0023 0.0029
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0062 0.0493
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Brugia malayi Angiotensin-converting enzyme family protein 0.1497 0.7924 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0131 0.0452
Trichomonas vaginalis aldo/keto reductase, putative 0.0162 0.0775 0.2848
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Loa Loa (eye worm) fibroinase 0.0032 0.0084 0.0105
Schistosoma mansoni nuclear receptor 0.0071 0.0291 0.029
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0004 0.0011
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0151 0.0717 0.0904
Loa Loa (eye worm) hypothetical protein 0.0253 0.1265 0.1596
Onchocerca volvulus 0.0102 0.0458 0.059
Echinococcus granulosus caspase 8 0.0043 0.0142 0.0141
Onchocerca volvulus 0.0074 0.0305 0.0392
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0011 0.0141
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Echinococcus granulosus single minded 2 0.0073 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0023 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0103 0.0129
Leishmania major cytochrome p450-like protein 0.0044 0.0146 0.1872
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0077
Brugia malayi Tyrosine-protein kinase abl-1 0.0021 0.0023 0.0028
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0011 0.0035
Echinococcus granulosus aldo keto reductase 0.0162 0.0775 0.0774
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0177 0.0858 0.2971
Entamoeba histolytica hypothetical protein 0.0074 0.0306 0.3947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Plasmodium vivax multidomain scavenger receptor, putative 0.0315 0.1597 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0116 0.0146
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0249 0.1242 0.1242
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0011 0.0148
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0306 0.0305
Treponema pallidum quinoline 2-oxidoreductase 0.0083 0.0356 0.0314
Schistosoma mansoni rab6-interacting 0.0315 0.1597 0.1597
Echinococcus multilocularis 0.0018 0.0004 0.0004
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0023 0.0023
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0028 0.0062 0.0077
Onchocerca volvulus 0.0019 0.001 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0151 0.0717 0.0717
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0291 0.0374
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0023 0.0023
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0118 0.0117
Echinococcus multilocularis tyrosine protein kinase Blk 0.0021 0.0023 0.0023
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0094 0.0093
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0118 0.0117
Onchocerca volvulus 0.0019 0.0011 0.0014
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0146 0.1872
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0011 0.004
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0136 0.1748
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0116 0.0426
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0004 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0337 0.0424
Onchocerca volvulus 0.0022 0.0027 0.0034
Schistosoma mansoni tyrosine kinase 0.0021 0.0023 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0223 0.0281
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0238 0.0762
Onchocerca volvulus 0.0055 0.0205 0.0263
Brugia malayi glutaminase DH11.1 0.0266 0.1331 0.168
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0249 0.1242 1
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0011 0.0096
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0116 0.1502
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Echinococcus granulosus intermediate filament protein 0.0055 0.0205 0.0204
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0011 0.0011
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0034 0.0114
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0171 0.2207
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0034 0.0106
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0151 0.0717 0.0717
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0011 0.0141
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0118 0.0117
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0011 0.0068
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0011 0.0141
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0023 0.0299
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0556 0.2888 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0312 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.0573 0.739
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Brugia malayi cathepsin L-like precursor 0.0022 0.0027 0.0033
Brugia malayi Bromodomain containing protein 0.0028 0.0062 0.0077
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0238 0.0237
Schistosoma mansoni sodium/chloride dependent transporter 0.0249 0.1242 0.1242
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0011 0.0011
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0054 0.0197 0.0248
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0011 0.0035
Onchocerca volvulus Putative organic anion transporter 0.011 0.0499 0.0642
Schistosoma mansoni lamin 0.0055 0.0205 0.0204
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0034 0.0433
Brugia malayi SWIRM domain containing protein 0.0042 0.0136 0.0171
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0047 0.0161 0.0589
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0401 0.5179
Loa Loa (eye worm) hypothetical protein 0.0075 0.0312 0.0393
Echinococcus multilocularis aldehyde reductase 0.0115 0.0524 0.0524
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0011 0.0088
Leishmania major dehydrogenase-like protein 0.0019 0.0011 0.0141
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0162 0.0775 0.0977
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0151 0.0717 0.0717
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Brugia malayi nuclear hormone receptor family member odr-7 0.0071 0.0291 0.0366
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0011 0.0038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0023 0.0023
Onchocerca volvulus Matrilysin homolog 0.0019 0.001 0.0012
Echinococcus multilocularis lamin 0.0055 0.0205 0.0204
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0141
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0148 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0004 0.0012
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0141
Echinococcus granulosus voltage gated potassium channel subunit 0.0047 0.0161 0.016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0001 0.0000085038
Onchocerca volvulus 0.0019 0.0011 0.0014
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0011 0.0011
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0177 0.0858 0.2756
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0011 0.0011
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0065
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0081 0.0081
Leishmania major short chain dehydrogenase, putative 0.0019 0.0011 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0075 0.0312 0.2508
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0071 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0011 0.0038
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0177 0.0858 0.2756
Loa Loa (eye worm) hypothetical protein 0.0043 0.0142 0.0178
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0148 0.0147
Plasmodium falciparum aldehyde reductase, putative 0.0047 0.0161 0.1003
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0011 0.0035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Loa Loa (eye worm) hypothetical protein 0.0053 0.0196 0.0246
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0011 0.0035
Echinococcus multilocularis Small ubiquitin modifier 2 0.003 0.007 0.0069
Echinococcus multilocularis serotonin transporter 0.1466 0.7756 0.7756
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0004 0.0011
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0401 0.0517
Toxoplasma gondii small ubiquitin family modifier, putative 0.003 0.007 0.0557
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0004 0.0012
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0023 0.0023
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0044 0.0147 0.0147
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0096
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0717 0.0717
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0148 0.0147
Schistosoma mansoni hypothetical protein 0.004 0.0126 0.0125
Onchocerca volvulus 0.1466 0.7756 1
Onchocerca volvulus 0.0162 0.0775 0.0998
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0004 0.0012
Echinococcus granulosus organic anion transporting polypeptide 30B 0.011 0.0499 0.0498
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.0171 0.0629
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0249 0.1242 0.1242
Entamoeba histolytica hypothetical protein 0.0019 0.0011 0.0148
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0034 0.0426
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Loa Loa (eye worm) doublecortin family protein 0.0315 0.1597 0.2015
Brugia malayi hypothetical protein 0.0249 0.1242 0.1567
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0151 0.0717 0.0904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Brugia malayi hypothetical protein 0.0253 0.1265 0.1596
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0004 0.0012
Leishmania major cathepsin L-like protease 0.0124 0.0573 0.739
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0011 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0028 0.0062 0.0077
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Schistosoma mansoni nuclear receptor 0.0071 0.0291 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Treponema pallidum hypothetical protein 0.0085 0.0367 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Plasmodium vivax hypothetical protein, conserved 0.0249 0.1242 0.7777
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0151 0.0717 0.0717
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0062 0.0061
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0028 0.0062 0.0061
Echinococcus granulosus geminin 0.0348 0.1771 0.177
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Schistosoma mansoni rab6-interacting 0.0315 0.1597 0.1597
Onchocerca volvulus Cathepsin L homolog 0.0032 0.0084 0.0108
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Leishmania major small ubiquitin protein, putative 0.003 0.007 0.0894
Toxoplasma gondii aldose reductase, putative 0.0162 0.0775 0.6235
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0004 0.0011
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0249 0.1242 0.1242
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.008 0.0337 0.0336
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0011 0.0088
Onchocerca volvulus 0.0055 0.0205 0.0263
Schistosoma mansoni glutaminase 0.0266 0.1331 0.1331
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0118 0.1513
Schistosoma mansoni lipoxygenase 0.1885 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0034 0.0426
Giardia lamblia Aldose reductase 0.0162 0.0775 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0011 0.0148
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0011 0.0038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Onchocerca volvulus 0.0019 0.0011 0.0014
Toxoplasma gondii hypothetical protein 0.0249 0.1242 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.007 0.0255
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0136 0.0435
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0052 0.0052
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0341 0.4392
Onchocerca volvulus Bile acid receptor homolog 0.0151 0.0717 0.0924
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0148 0.0147
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1466 0.7756 0.9789
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0116 0.1495
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0162 0.0775 0.2848
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0116 0.1495
Schistosoma mansoni sodium/chloride dependent transporter 0.1466 0.7756 0.7756
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0148 0.0186
Onchocerca volvulus Cell death protein 3 homolog 0.0083 0.0357 0.0459
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0042
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0011 0.0038
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0011 0.0141
Echinococcus granulosus caspase 2 0.0083 0.0357 0.0356
Entamoeba histolytica deoxycytidyl transferase, putative 0.0028 0.0062 0.08
Onchocerca volvulus Matrilysin homolog 0.0041 0.0132 0.0169
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.1265 0.1264
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0001 0.0000085038
Echinococcus granulosus serotonin transporter 0.1466 0.7756 0.7756
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0004 0.0011
Schistosoma mansoni caspase-3 (C14 family) 0.0114 0.0522 0.0521
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.003 0.007 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0004 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Brugia malayi oxidoreductase 0.0019 0.0011 0.0014
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0011 0.0011
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0525 0.2719 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0401 0.5175
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0011 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0341 0.4392
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0011 0.0068
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.0171 0.0629
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0019 0.001 0.001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Echinococcus granulosus cathepsin l1 0.0022 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.1466 0.7756 0.9789
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0011 0.0011
Brugia malayi Matrixin family protein 0.0019 0.001 0.0012
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0011 0.0011
Echinococcus multilocularis cathepsin L cysteine protease 0.0032 0.0084 0.0084
Schistosoma mansoni single-minded 0.0122 0.0564 0.0564
Schistosoma mansoni sodium/chloride dependent transporter 0.0249 0.1244 0.1243
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0033 0.004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0151 0.0717 0.0717
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0018 0.0107
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0004 0.0046
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Brugia malayi sodium-independent organic anion transporter family protein 0.011 0.0499 0.0629
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0049 0.0173 0.0172
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0011 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Schistosoma mansoni organic anion transporter 0.011 0.0499 0.0498
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0002 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0034 0.0382
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Onchocerca volvulus 0.011 0.0499 0.0642
Plasmodium falciparum small ubiquitin-related modifier 0.003 0.007 0.0433
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Giardia lamblia DINP protein human, muc B family 0.0041 0.0131 0.1686
Plasmodium vivax vivapain-2 0.0032 0.0084 0.0523
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0158
Trypanosoma brucei metacaspase 0.0043 0.0142 0.1821
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0075 0.0312 0.0393
Schistosoma mansoni lamin 0.0055 0.0205 0.0204
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Loa Loa (eye worm) hypothetical protein 0.0049 0.017 0.0214
Mycobacterium ulcerans oxidoreductase 0.0019 0.0011 0.0035
Echinococcus multilocularis tyrosine protein kinase Abl 0.0021 0.0023 0.0023
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0033 0.0118
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0424
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0116 0.0401
Schistosoma mansoni hypothetical protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0042
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0011 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0424
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0011 0.0014
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0011 0.0038
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0011 0.0038
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0011 0.0014
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0057 0.0352
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0196 0.0246
Schistosoma mansoni pol-related 0.0162 0.0775 0.0774
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0238 0.0237
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0071 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0004 0.0012
Leishmania major cytochrome p450-like protein 0.0018 0.0004 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0004 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0034 0.0382
Echinococcus multilocularis peregrin 0.0028 0.0062 0.0061
Loa Loa (eye worm) oxidoreductase 0.0162 0.0775 0.0977
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0141
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0011 0.0148
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Toxoplasma gondii transporter, major facilitator family protein 0.011 0.0499 0.4012
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0068 0.0085
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0151 0.0717 0.0717
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0151 0.0717 0.0904
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0142 0.1821
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0401 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0153 0.0562
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.1242 0.1567
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Echinococcus multilocularis 0.0042 0.0136 0.0135
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0032 0.0084 0.0523
Schistosoma mansoni cathepsin F (C01 family) 0.0032 0.0084 0.0084
Mycobacterium leprae PROBABLE HYDROLASE 0.0023 0.0032 0.0361
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Loa Loa (eye worm) TK/ABL protein kinase 0.0021 0.0023 0.0028
Brugia malayi SPARC precursor 0.0075 0.0312 0.0393
Onchocerca volvulus 0.011 0.0499 0.0642
Leishmania major hypothetical protein, conserved 0.0027 0.0057 0.0725
Trichomonas vaginalis aldo-keto reductase, putative 0.0047 0.0161 0.0589
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0132
Leishmania major oxidoreductase-like protein 0.0019 0.0011 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0034 0.0042
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0071 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.008 0.0337 0.0424
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0717 0.0904
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0011 0.0035
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0011 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Brugia malayi hypothetical protein 0.0054 0.0197 0.0248
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0027 0.0096
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0065
Brugia malayi Matrixin family protein 0.0019 0.001 0.0012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Giardia lamblia Reductase, putative 0.0019 0.0011 0.0141
Brugia malayi jmjC domain containing protein 0.0034 0.0094 0.0118
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0248
Loa Loa (eye worm) hypothetical protein 0.0409 0.2102 0.2652
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0011 0.0035
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0034 0.0426
Loa Loa (eye worm) hypothetical protein 0.0075 0.0312 0.0393
Schistosoma mansoni coup transcription factor 0.0151 0.0717 0.0717
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0125 0.0579 0.073
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0291 0.029
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0136 0.0469
Onchocerca volvulus 0.0254 0.1268 0.1634
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0081 0.065
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0291 0.029
Echinococcus multilocularis caspase 0.0114 0.0522 0.0521
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.008 0.0337 0.0336
Brugia malayi hypoxia-induced factor 1 0.0307 0.1553 0.196
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0162 0.0775 0.0977
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0249 0.1242 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0002 0.0006
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0004 0.0012
Schistosoma mansoni sodium-dependent amino acid transporter 0.0249 0.1242 0.1242
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Echinococcus granulosus tyrosine protein kinase ABL1 0.0021 0.0023 0.0023
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0011 0.0148
Mycobacterium ulcerans hypothetical protein 0.0085 0.0367 0.1176
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0011 0.0011
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0156 0.0743 0.2384
Schistosoma mansoni amine oxidase 0.0042 0.0136 0.0135
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0011 0.0035
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0011 0.0141
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0007 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0341 0.4392
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0125 0.0579 0.0579
Brugia malayi hypothetical protein 0.0019 0.0011 0.0014
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.011 0.0499 0.0498
Echinococcus multilocularis tyrosine protein kinase Srms 0.0021 0.0023 0.0023
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0103 0.046 0.058
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Brugia malayi hypothetical protein 0.011 0.0499 0.0629
Brugia malayi Matrixin family protein 0.0019 0.001 0.0012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0407 0.0406
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0034 0.0114
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0081 0.0081
Brugia malayi hypothetical protein 0.0054 0.0199 0.025
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Trypanosoma cruzi aldo/keto reductase, putative 0.0162 0.0775 1
Echinococcus multilocularis tyrosine kinase 0.0021 0.0023 0.0023
Onchocerca volvulus Putative organic anion transporter 0.011 0.0499 0.0642
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0011 0.0141
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Onchocerca volvulus 0.0021 0.0023 0.0029
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0004 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0071 0.0291 0.0366
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0068 0.0085
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0114 0.0522 0.0521
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0011 0.0011
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0599 0.3114 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0151 0.0717 0.0717
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0116 0.0116
Brugia malayi Cell death protein 3 precursor 0.0083 0.0357 0.045
Loa Loa (eye worm) dehydrogenase 0.0019 0.0011 0.0014
Echinococcus granulosus aldo keto reductase 0.0162 0.0775 0.0774
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0249 0.1242 0.1567
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.01 0.0446 0.1432
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0238 0.3065
Leishmania major aldo-keto reductase-like protein 0.0162 0.0775 1
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0068 0.0273 0.0273
Entamoeba histolytica hypothetical protein 0.0074 0.0306 0.3947
Loa Loa (eye worm) hypoxia-induced factor 1 0.0307 0.1553 0.196
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0004 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0118 0.1513
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.000006738
Echinococcus granulosus aryl hydrocarbon receptor 0.0103 0.046 0.0459
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0136 0.171
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Mycobacterium leprae Conserved hypothetical protein 0.0115 0.0524 0.6751
Leishmania major metacaspase, putative 0.0043 0.0142 0.1821
Loa Loa (eye worm) glutaminase 0.0266 0.1331 0.168
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0424
Brugia malayi Cytochrome P450 family protein 0.0044 0.0146 0.0183
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0009
Brugia malayi PHD-finger family protein 0.0028 0.0062 0.0077
Trypanosoma cruzi metacaspase, putative 0.0043 0.0142 0.1821
Loa Loa (eye worm) solute carrier family 6 member 4 0.1466 0.7756 0.9789
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0088
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0136 0.0469
Plasmodium vivax metacaspase 1, putative 0.0043 0.0142 0.0883
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0238 0.0237
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0151 0.0717 0.0717
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0116 1
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0011 0.0096
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0146 0.0183
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0106 0.0478 0.0603
Toxoplasma gondii cathepsin CPL 0.0032 0.0084 0.0673
Loa Loa (eye worm) nuclear receptor NHR-67 0.0071 0.0291 0.0366
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0011 0.0011
Echinococcus granulosus Polycystic kidney disease protein 0.0315 0.1597 0.1597
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0248
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.007 0.0894
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0011 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0151 0.0717 0.0904
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0075 0.0312 0.2508
Toxoplasma gondii aldo-keto reductase 0.0047 0.0161 0.1289
Echinococcus granulosus cathepsin l cysteine peptidase 0.0032 0.0084 0.0084
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Brugia malayi hypothetical protein 0.0027 0.0057 0.0071
Echinococcus granulosus sodium and chloride dependent glycine 0.0249 0.1242 0.1242
Giardia lamblia Hypothetical protein 0.0019 0.0011 0.0141
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0057 0.0725
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0049 0.0171 0.0629
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0023 0.0032 0.0109
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0023 0.0023
Schistosoma mansoni ap endonuclease 0.0038 0.0116 0.0116
Onchocerca volvulus 0.0019 0.0011 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0077
Schistosoma mansoni lipoxygenase 0.1318 0.6964 0.6964
Echinococcus multilocularis nuclear receptor nhr 48 0.0071 0.0291 0.029
Trypanosoma brucei small ubiquitin-related modifier 0.003 0.007 0.0894
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Echinococcus granulosus Solute carrier organic anion transporter family 0.011 0.0499 0.0498
Onchocerca volvulus 0.0052 0.0187 0.024
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0004 0.0012
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0004 0.0046
Onchocerca volvulus 0.0162 0.0775 0.0998
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0084 0.1086
Onchocerca volvulus 0.0019 0.0011 0.0014
Loa Loa (eye worm) CYP4Cod1 0.0044 0.0146 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0004 0.0011
Onchocerca volvulus Matrix metalloproteinase homolog 0.0041 0.0132 0.0169
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0011 0.0038
Entamoeba histolytica hypothetical protein 0.0074 0.0306 0.3947
Schistosoma mansoni tyrosine kinase 0.0021 0.0023 0.0023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.000006738
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Onchocerca volvulus 0.0151 0.0717 0.0924
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Echinococcus multilocularis lamin dm0 0.0055 0.0205 0.0204
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0023 0.0023
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0002 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0151 0.0717 0.0904
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0081 0.0081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0116 0.1495
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Trypanosoma brucei Metacaspase-4 0.0043 0.0142 0.1821
Leishmania major cysteine peptidase A (CPA) 0.0032 0.0084 0.1079
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0171 0.0629
Onchocerca volvulus 0.0021 0.0023 0.0029
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0162 0.0775 0.2848
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1497 0.7924 1
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0337 0.0424
Toxoplasma gondii protease inhibitor PI2 0.0075 0.0312 0.2508
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0004 0.0012
Loa Loa (eye worm) steroid hormone receptor 0.0151 0.0717 0.0904
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Onchocerca volvulus 0.0032 0.0084 0.0108
Mycobacterium ulcerans short chain dehydrogenase 0.0555 0.2881 0.9253
Schistosoma mansoni hypothetical protein 0.0028 0.0062 0.0061
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.1265 0.1264
Trichomonas vaginalis aldehyde oxidase, putative 0.0525 0.2719 1
Trypanosoma cruzi metacaspase, putative 0.0043 0.0142 0.1821
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0004 0.0012
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0032 0.0084 0.0105
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0088
Brugia malayi Protein kinase domain containing protein 0.0021 0.0023 0.0028
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0011 0.0148
Loa Loa (eye worm) hypothetical protein 0.1466 0.7756 0.9789
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0141
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0004 0.0011
Trypanosoma brucei polo-like protein kinase 0.0092 0.0401 0.5175
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0062 0.0493
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0047 0.0161 0.1003
Brugia malayi prostaglandin transporter 0.011 0.0499 0.0629
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0088
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0057 0.0725
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0011 0.0141
Brugia malayi hypothetical protein 0.0042 0.0136 0.0171
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Onchocerca volvulus 0.0249 0.1242 0.1601
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.0171 0.0629
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Trypanosoma cruzi metacaspase, putative 0.0043 0.0142 0.1821
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0249 0.1242 0.1242
Mycobacterium ulcerans oxidoreductase 0.0162 0.0775 0.2487
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0136 0.0135
Schistosoma mansoni aryl hydrocarbon receptor 0.0122 0.0566 0.0565
Brugia malayi photoreceptor-specific nuclear receptor 0.0151 0.0717 0.0904
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0142 0.1135
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0151 0.0717 0.0717
Schistosoma mansoni loxhd1 0.0315 0.1597 0.1597
Echinococcus granulosus cathepsin l1 0.0032 0.0084 0.0084
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0011 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0291 0.029
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0236 0.3041
Echinococcus multilocularis sodium and chloride dependent glycine 0.0249 0.1242 0.1242
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0401 0.5175
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0424
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Trichomonas vaginalis aldo/keto reductase, putative 0.0162 0.0775 0.2848
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.0171 0.0629
Mycobacterium tuberculosis Conserved protein 0.0047 0.0161 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0011 0.0141
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0049 0.0173 0.2228
Brugia malayi conserved hypotetical protein 0.0071 0.0291 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0004 0.0046
Loa Loa (eye worm) hypothetical protein 0.0061 0.0236 0.0297
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Brugia malayi ecdysone receptor 0.0071 0.0291 0.0366
Echinococcus multilocularis thyroid hormone receptor alpha 0.0151 0.0717 0.0717
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Schistosoma mansoni kinase 0.0047 0.016 0.0159
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0004 0.0011
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0238 0.0237
Schistosoma mansoni DNA polymerase eta 0.0028 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Echinococcus multilocularis transfer RNA-Lys 0.0073 0.0303 0.0303
Mycobacterium ulcerans hypothetical protein 0.0047 0.0161 0.0514
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0151 0.0717 0.0904
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0717 0.0904
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0011 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Schistosoma mansoni organic anion transporter 0.011 0.0499 0.0498
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0034 0.0433
Plasmodium falciparum metacaspase 1 0.0043 0.0142 0.0883
Schistosoma mansoni hypothetical protein 0.0348 0.1771 0.177
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0011 0.0038
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0034 0.0433
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0038
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0125 0.0579 0.2004
Echinococcus multilocularis tyrosine protein kinase shark 0.0718 0.3752 0.3752
Schistosoma mansoni agrin 0.0075 0.0312 0.0311
Leishmania major cathepsin L-like protease 0.0032 0.0084 0.1079
Brugia malayi hypothetical protein 0.0409 0.2102 0.2652
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0032 0.0084 0.0523
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Brugia malayi Cytochrome P450 family protein 0.0018 0.0004 0.0004
Entamoeba histolytica alcohol dehydrogenase, putative 0.0047 0.0161 0.2074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0136 0.109
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0004 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0084 0.1078
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Schistosoma mansoni aldo-keto reductase 0.0162 0.0775 0.0774
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0004 0.0046
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0011 0.0038
Schistosoma mansoni tyrosine kinase 0.0718 0.3752 0.3752
Plasmodium vivax aldehyde reductase, putative 0.0047 0.0161 0.1003
Loa Loa (eye worm) hypothetical protein 0.0075 0.0312 0.0393
Brugia malayi steroid hormone receptor 0.0151 0.0717 0.0904
Echinococcus multilocularis dna polymerase eta 0.0028 0.0062 0.0061
Schistosoma mansoni nuclear hormone receptor 0.0151 0.0717 0.0717
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0004 0.0012
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0023 0.0023
Schistosoma mansoni carbonyl reductase 0.0019 0.0011 0.0011
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Trypanosoma brucei aldo-keto reductase, putative 0.0162 0.0775 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0162 0.0775 0.2848
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0171 0.0629
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0401 0.1474
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0118 0.1519
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0011 0.0148
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0052 0.0052
Echinococcus multilocularis sodium and chloride dependent glycine 0.0249 0.1242 0.1242
Loa Loa (eye worm) hypothetical protein 0.0249 0.1242 0.1567
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0011 0.0088
Schistosoma mansoni potassium channel beta 0.0047 0.0161 0.016
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0011 0.0141
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0248
Schistosoma mansoni tyrosine kinase 0.0021 0.0023 0.0023
Brugia malayi hypothetical protein 0.0021 0.0023 0.0028
Loa Loa (eye worm) agrin synaptic family protein 0.0075 0.0312 0.0393
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0011 0.0011
Brugia malayi nuclear receptor NHR-88 0.0071 0.0291 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0011 0.0011
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0116 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0125 0.0579 0.0579
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.01 0.0446 0.1544
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0047 0.0161 0.1289
Giardia lamblia Aldose reductase 0.0162 0.0775 1
Echinococcus multilocularis expressed protein 0.0075 0.0312 0.0311
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0717 0.0904
Loa Loa (eye worm) hypothetical protein 0.0023 0.0032 0.004
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0049 0.0173 0.0172
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0019 0.0011 0.0944
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0171 0.2207
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0011 0.0038
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0136 0.0135
Trypanosoma cruzi cruzipain precursor, putative 0.0124 0.0573 0.739
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0151 0.0717 0.0717
Treponema pallidum hypothetical protein 0.007 0.0286 0.0222
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0146 0.1872
Onchocerca volvulus 0.0021 0.0023 0.0029
Echinococcus multilocularis GPCR, family 2 0.0017 0.0001 0.000006738
Echinococcus multilocularis voltage gated potassium channel subunit 0.0047 0.0161 0.016
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0136 0.0135
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0315 0.1597 0.2015
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0011 0.0141
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0118 0.0117
Loa Loa (eye worm) glutaminase 2 0.0266 0.1331 0.168
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0118 0.1513
Brugia malayi cytochrome P450 0.0018 0.0004 0.0004
Echinococcus granulosus aldo keto reductase 0.0162 0.0775 0.0774
Loa Loa (eye worm) serotonin transporter b 0.1466 0.7756 0.9789
Echinococcus granulosus neuropeptide receptor A26 0.0495 0.2559 0.2559
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0004 0.0012
Echinococcus multilocularis geminin 0.0348 0.1771 0.177
Echinococcus multilocularis aryl hydrocarbon receptor 0.0103 0.046 0.0459
Onchocerca volvulus 0.0019 0.0011 0.0014
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Echinococcus granulosus lipoxygenase domain containing protein 0.0315 0.1597 0.1597
Loa Loa (eye worm) hypothetical protein 0.0071 0.0291 0.0366
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Mycobacterium ulcerans hydrolase 0.0023 0.0032 0.0101
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0011 0.004
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0142 0.1135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0116 0.0372
Echinococcus granulosus hypothetical protein 0.0162 0.0775 0.0774
Trichomonas vaginalis DNA polymerase eta, putative 0.008 0.0341 0.1251
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0028 0.0062 0.0077
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0084 0.0105
Leishmania major prostaglandin f synthase, putative 0.0162 0.0775 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0291 0.029
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.0142 0.0141
Entamoeba histolytica alcohol dehydrogenase, putative 0.0047 0.0161 0.2074
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0014
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0023 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0004 0.0012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Echinococcus granulosus peregrin 0.0028 0.0062 0.0061
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0011 0.0014
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0011 0.0141
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0011 0.0141
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Brugia malayi Pre-SET motif family protein 0.0032 0.0081 0.0102
Schistosoma mansoni microtubule-associated protein tau 0.0674 0.3517 0.3517
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0042
Brugia malayi hypothetical protein 0.0074 0.0306 0.0385
Echinococcus granulosus lamin dm0 0.0055 0.0205 0.0204
Plasmodium falciparum amino acid transporter, putative 0.0249 0.1242 0.7777
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0011 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0717 0.0717
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0238 0.0762
Trypanosoma brucei unspecified product 0.002 0.0015 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0151 0.0717 0.0904
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0136 0.0848
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Trichomonas vaginalis aldo-keto reductase, putative 0.0047 0.0161 0.0589
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0125 0.0579 0.7476
Brugia malayi Ubiquitin-like protein SMT3 0.003 0.007 0.0087
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0136 0.0171
Leishmania major cathepsin L-like protease 0.0124 0.0573 0.739
Plasmodium vivax vivapain-2 0.0032 0.0084 0.0523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0151 0.0717 0.0904
Mycobacterium leprae Possible regulatory protein 0.0049 0.0171 0.2172
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0011 0.0038
Brugia malayi sodium-independent organic anion transporter family protein 0.011 0.0499 0.0629
Schistosoma mansoni hypothetical protein 0.0036 0.0105 0.0105
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0291 0.029
Brugia malayi Cathepsin L-like precursor 0.0032 0.0084 0.0105
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0084 0.1079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0081 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0118 0.0431
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0151 0.0717 0.0717
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0187 0.0235
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0084 0.0307
Loa Loa (eye worm) TK protein kinase 0.0021 0.0023 0.0028
Echinococcus multilocularis oxidoreductase 0.0019 0.0011 0.0011
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0047 0.0161 0.016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0116 0.0725
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0131 0.1686
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0062 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Plasmodium falciparum cysteine proteinase falcipain 3 0.0032 0.0084 0.0523
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0062 0.0383
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0141
Echinococcus granulosus GPCR family 2 0.0017 0.0001 0.000006738
Trichomonas vaginalis aldo-keto reductase, putative 0.0162 0.0775 0.2848
Echinococcus granulosus tyrosine protein kinase shark 0.0718 0.3752 0.3752
Brugia malayi intermediate filament protein 0.0055 0.0205 0.0257
Leishmania major protein kinase, putative 0.0049 0.0173 0.2228
Onchocerca volvulus 0.0032 0.0084 0.0108
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0717 0.0904
Onchocerca volvulus Cathepsin F homolog 0.0032 0.0084 0.0108
Brugia malayi Protein kinase domain containing protein 0.0021 0.0023 0.0028
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0162 0.0775 0.0977
Plasmodium falciparum aldo-keto reductase, putative 0.0047 0.0161 0.1003
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0205 0.0257
Echinococcus granulosus microtubule associated protein 2 0.0674 0.3517 0.3517
Loa Loa (eye worm) ctsf protein 0.0032 0.0084 0.0105
Loa Loa (eye worm) matrixin family protein 0.0045 0.0152 0.0191
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0162 0.0775 0.0774
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0151 0.0717 0.0904
Entamoeba histolytica ubiquitin like protein 0.003 0.007 0.09
Loa Loa (eye worm) hypothetical protein 0.0042 0.0136 0.0171
Brugia malayi SRC-1 0.0021 0.0023 0.0028
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0136 0.0848
Brugia malayi Cathepsin L-like precursor 0.0022 0.0027 0.0033
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0054 0.0199 0.0198
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0011 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0291 0.0374
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.0171 0.0629
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Echinococcus multilocularis Polycystic kidney disease protein 0.0315 0.1597 0.1597
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Brugia malayi nuclear receptor RXR 0.0071 0.0291 0.0366
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0142 0.0519
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0011 0.0141
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0142 0.1135
Loa Loa (eye worm) norepinephrine transporter 0.1466 0.7756 0.9789
Echinococcus multilocularis caspase 2 0.0083 0.0357 0.0356
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0011 0.0038
Schistosoma mansoni zinc finger protein 0.0071 0.0291 0.029
Mycobacterium ulcerans hypothetical protein 0.0023 0.0034 0.0106
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0136 0.0848
Mycobacterium tuberculosis Probable oxidoreductase 0.0555 0.2881 0.9976
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.1102 0.1391
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0011 0.0035
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0049 0.0173 0.2228
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0126 0.0125
Leishmania major cathepsin L-like protease 0.0032 0.0084 0.1079
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0011 0.004
Brugia malayi protein-tyrosine kinase 0.0021 0.0023 0.0028
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0004 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0057 0.0452
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0054 0.0199 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0142 0.0519
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0011 0.0011
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0011 0.0035
Trypanosoma brucei metacaspase MCA3 0.0043 0.0142 0.1821
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0341 0.4392
Echinococcus granulosus FTZ F1 alpha 0.0151 0.0717 0.0717
Loa Loa (eye worm) oxidoreductase 0.0019 0.0011 0.0014
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1885 1 1
Brugia malayi hypothetical protein 0.008 0.0337 0.0424
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0011 0.0014
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0162 0.0775 0.0774
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0084 0.0307
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0034 0.0106
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.0027 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0118 0.0148
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0118 0.1513
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0042 0.0136 0.109
Echinococcus multilocularis aldo keto reductase 0.0162 0.0775 0.0774
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0071 0.0291 0.029
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Onchocerca volvulus 0.0023 0.0034 0.0042
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0011 0.0014
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0049 0.0173 0.2228
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0151 0.0717 0.0904
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0004 0.0011
Brugia malayi sodium-independent organic anion transporter family protein 0.011 0.0499 0.0629
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0011 0.0035
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0034 0.0106
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0249 0.1242 0.1242
Brugia malayi Matrixin family protein 0.0019 0.001 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.0171 0.0629
Echinococcus granulosus sodium and chloride dependent glycine 0.0249 0.1242 0.1242
Brugia malayi nuclear hormone receptor 0.0151 0.0717 0.0904
Plasmodium falciparum phd finger protein, putative 0.0028 0.0062 0.0383
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.0171 0.0629
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0033
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0057 0.0725
Brugia malayi nuclear hormone receptor 0.0071 0.0291 0.0366
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0004 0.0011
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0023 0.0023
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0075 0.0312 0.0393
Loa Loa (eye worm) hypothetical protein 0.011 0.0499 0.0629
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0011 0.0014
Schistosoma mansoni hypothetical protein 0.0105 0.0475 0.0474
Trypanosoma cruzi aldo-keto reductase 0.0162 0.0775 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0027 0.0096
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0011 0.0014
Onchocerca volvulus 0.004 0.0126 0.0161
Echinococcus multilocularis aldo keto reductase 0.0162 0.0775 0.0774
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0599 0.3114 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0125 0.0579 0.1859
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0151 0.0717 0.0717
Trypanosoma brucei DNA polymerase IV, putative 0.008 0.0341 0.4392
Mycobacterium ulcerans oxidoreductase 0.0042 0.0136 0.0435
Brugia malayi SH2 domain containing protein 0.0021 0.0023 0.0028
Echinococcus granulosus neuropeptide s receptor 0.0495 0.2559 0.2559
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0084 0.1086
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0011 0.0011
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0011 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0161 0.0589
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0004 0.0046
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0027 0.0344
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0291 0.0366
Plasmodium vivax amine transporter, putative 0.0249 0.1242 0.7777
Leishmania major UDP-galactopyranose mutase 0.0042 0.0136 0.1748
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0116 0.0426
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0717 0.0904
Mycobacterium ulcerans DNA polymerase IV 0.008 0.0341 0.1092
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0011 0.0141
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0118 0.1513
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0424
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0151 0.0717 0.0924
Loa Loa (eye worm) cytochrome P450 0.0018 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0315 0.1597 0.1597
Schistosoma mansoni ap endonuclease 0.0038 0.0116 0.0116
Brugia malayi SH2 domain containing protein 0.0021 0.0023 0.0028
Leishmania major cathepsin L-like protease 0.0032 0.0084 0.1079
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0238 0.0822
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0023 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0032 0.0084 0.0307
Loa Loa (eye worm) hypothetical protein 0.0315 0.1597 0.2015
Echinococcus granulosus dna polymerase eta 0.0028 0.0062 0.0061
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0094 0.0093
Brugia malayi nuclear receptor NHR-67 0.0071 0.0291 0.0366
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0118 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0032 0.0084 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0573 0.739
Onchocerca volvulus 0.0019 0.0011 0.0014
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0032 0.0084 0.0084
Schistosoma mansoni carbonyl reductase 0.0019 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.0573 0.739
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0171 0.0629
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0011 0.0038
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0011 0.0141
Brugia malayi Protein kinase domain containing protein 0.0021 0.0023 0.0028
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0401 0.0506
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0084 0.0105
Brugia malayi hypothetical protein 0.0019 0.0011 0.0014
Echinococcus granulosus tyrosine protein kinase Blk 0.0021 0.0023 0.0023
Onchocerca volvulus 0.0249 0.1242 0.1601
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.0271 0.3499
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0247 0.1234 0.4273
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0011 0.0035
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0004 0.0011

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 33 nM In vitro inhibition of angiotensin I converting enzyme (ACE) ChEMBL. 6310113
IC50 (binding) = 33 nM In vitro inhibition of angiotensin I converting enzyme (ACE) ChEMBL. 6310113

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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