Detailed information for compound 368117

Basic information

Technical information
  • TDR Targets ID: 368117
  • Name: 1-phenyl-8-(1-propan-2-ylcyclohexyl)-3,8-diaz aspiro[4.5]decan-4-one
  • MW: 354.529 | Formula: C23H34N2O
  • H donors: 1 H acceptors: 1 LogP: 4.34 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C1(CCCCC1)N1CCC2(CC1)C(=O)NCC2c1ccccc1)C
  • InChi: 1S/C23H34N2O/c1-18(2)23(11-7-4-8-12-23)25-15-13-22(14-16-25)20(17-24-21(22)26)19-9-5-3-6-10-19/h3,5-6,9-10,18,20H,4,7-8,11-17H2,1-2H3,(H,24,26)
  • InChiKey: NSEZFRRUDHGUMJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 8-(1-isopropylcyclohexyl)-1-phenyl-3,8-diazaspiro[4.5]decan-4-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium- and chloride-dependent glycine transporter 1, putative Get druggable targets OG5_128673 All targets in OG5_128673
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128673 All targets in OG5_128673
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128673 All targets in OG5_128673
Echinococcus granulosus sodium and chloride dependent glycine Get druggable targets OG5_128673 All targets in OG5_128673
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128673 All targets in OG5_128673
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128673 All targets in OG5_128673
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Get druggable targets OG5_128673 All targets in OG5_128673
Echinococcus granulosus sodium and chloride dependent glycine Get druggable targets OG5_128673 All targets in OG5_128673
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128673 All targets in OG5_128673
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128673 All targets in OG5_128673
Schistosoma japonicum Sodium-dependent proline transporter, putative Get druggable targets OG5_128673 All targets in OG5_128673
Echinococcus multilocularis sodium and chloride dependent glycine Get druggable targets OG5_128673 All targets in OG5_128673
Echinococcus multilocularis sodium and chloride dependent glycine Get druggable targets OG5_128673 All targets in OG5_128673
Schistosoma japonicum Sodium- and chloride-dependent glycine transporter 1, putative Get druggable targets OG5_128673 All targets in OG5_128673
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis serotonin transporter solute carrier family 6 (neurotransmitter transporter, glycine), member 9 633 aa 616 aa 38.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni pyruvate dehydrogenase 0.0026 0.0022 0.0022
Echinococcus granulosus mothers against decapentaplegic 2 0.0033 0.0036 0.0035
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0125 0.0447
Schistosoma mansoni protein kinase 0.0118 0.0216 0.0216
Brugia malayi sulfakinin receptor protein 0.0075 0.0125 0.0447
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0099 0.2043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0194 0.0791
Leishmania major hypothetical protein, conserved 0.0021 0.0011 0.0201
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0026 0.0022 0.0113
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0125 0.0125
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0122 0.0223 0.0798
Trichomonas vaginalis D-aminoacylase, putative 0.0198 0.0385 0.1589
Onchocerca volvulus Alhambra homolog 0.0144 0.027 0.1125
Echinococcus granulosus tyrosine kinase 0.0118 0.0216 0.0215
Loa Loa (eye worm) hypothetical protein 0.0167 0.0319 0.114
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0022 0.0013 0.0013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0613 0.126 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi G-protein coupled receptor 0.0075 0.0125 0.0447
Schistosoma mansoni glutaminase 0.0341 0.0686 0.0686
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.1461 0.3049 0.3049
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0125 0.0125
Schistosoma mansoni neuropeptide receptor 0.0075 0.0125 0.0125
Echinococcus granulosus PH interacting protein 0.0021 0.0011 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0296
Schistosoma mansoni lipoxygenase 0.0727 0.15 0.15
Trypanosoma cruzi ISWI complex protein 0.0112 0.0203 0.4236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0159 0.0301 0.1241
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.009 0.0321
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.002 0.0008 0.0118
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.009 0.0156 0.1037
Brugia malayi TAZ zinc finger family protein 0.0021 0.0011 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0199 0.0387 0.1601
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0125 0.0125
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0021 0.0011 0.0201
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0042 0.0851
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.052 0.1064 0.1063
Echinococcus multilocularis nmda type glutamate receptor 0.1748 0.3655 0.3654
Giardia lamblia GTOR 0.0199 0.0387 0.2636
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.002
Schistosoma mansoni polybromo-1 0.0021 0.0011 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0098 0.0796
Schistosoma mansoni hypothetical protein 0.0836 0.1731 0.1731
Brugia malayi calpain family protein 1 0.0041 0.0052 0.0186
Trypanosoma brucei heat shock protein 90, putative 0.0135 0.0251 0.2054
Brugia malayi jmjC domain containing protein 0.0134 0.0249 0.0891
Schistosoma mansoni DNA polymerase eta 0.0065 0.0103 0.0103
Leishmania major basic transcription factor 3a, putative 0.0075 0.0124 0.2582
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0124 0.0501
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0026 0.0022 0.0063
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0059 0.009 0.0089
Trypanosoma brucei hypothetical protein, conserved 0.0198 0.0385 0.3146
Leishmania major cathepsin L-like protease 0.0069 0.0111 0.2308
Loa Loa (eye worm) norepinephrine transporter 0.0019 0.0006 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.0122
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0125 0.0125
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.004 0.0052 0.0051
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1461 0.3049 0.3049
Echinococcus multilocularis survival motor neuron protein 1 0.0403 0.0817 0.0817
Schistosoma mansoni hypothetical protein 0.0136 0.0254 0.0254
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0026 0.0022 0.0063
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni biogenic amine receptor 0.0075 0.0125 0.0125
Trypanosoma cruzi extracellular receptor, putative 0.0118 0.0216 0.4505
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Leishmania major cathepsin L-like protease 0.0018 0.0004 0.0057
Echinococcus granulosus inositol monophosphatase 1 0.0021 0.0011 0.0011
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Mycobacterium tuberculosis Probable esterase LipL 0.0198 0.0385 0.144
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0026 0.0022 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0223 0.0223
Onchocerca volvulus 0.0061 0.0095 0.0397
Echinococcus multilocularis NMDA receptor 0.0501 0.1025 0.1024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0007 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0059 0.009 0.0089
Schistosoma mansoni nuclear hormone receptor 0.0059 0.009 0.009
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0183 0.0746
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.009 0.0089
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0183 0.3146
Loa Loa (eye worm) serotonin transporter b 0.0019 0.0006 0.002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0134 0.0249 0.0891
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1549
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.009 0.0321
Loa Loa (eye worm) hypothetical protein 0.0371 0.075 0.2678
Brugia malayi larval opioid receptor 0.0075 0.0125 0.0447
Echinococcus multilocularis polycomb protein SCMH1 0.0116 0.0211 0.0211
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0015 0.0053
Schistosoma mansoni hypothetical protein 0.0174 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.0062
Brugia malayi acetyltransferase, GNAT family protein 0.0177 0.0341 0.1218
Schistosoma mansoni amine GPCR 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0036 0.0043 0.0153
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0134 0.0249 0.5215
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0059 0.0091 0.0736
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Onchocerca volvulus 0.0021 0.0011 0.0047
Toxoplasma gondii heat shock protein 75, putative 0.006 0.0094 0.1601
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0026 0.0022 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0249 0.1021
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.041
Trypanosoma brucei glucose transporter 1E 0.0032 0.0034 0.0269
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0125 0.0447
Echinococcus multilocularis dna polymerase eta 0.0065 0.0103 0.0102
Brugia malayi Cam kinase protein 1 0.0032 0.0034 0.0123
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.0084
Echinococcus granulosus receptor type guanylyl cyclase 0.0118 0.0216 0.0215
Trypanosoma brucei heat shock protein 90, putative 0.0135 0.0251 0.2054
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0034 0.038
Brugia malayi hypothetical protein 0.0028 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0136 0.0254 0.0907
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0029 0.0584
Trichomonas vaginalis sensor histidine kinase, putative 0.0026 0.0022 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0145 0.0273 0.0273
Trichomonas vaginalis D-aminoacylase, putative 0.0198 0.0385 0.1589
Echinococcus multilocularis neuropeptide s receptor 0.0596 0.1223 0.1223
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.004 0.0052 0.0052
Onchocerca volvulus 0.0116 0.0211 0.0882
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0431 0.0876 0.3127
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0034 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.003 0.0029 0.0029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0013 0.0217
Onchocerca volvulus 0.1152 0.2397 1
Schistosoma mansoni smad1 5 8 and 0.0073 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0185
Schistosoma mansoni DNA polymerase IV / kappa 0.0017 0.0002 0.0002
Schistosoma mansoni histamine h1 receptor 0.0075 0.0125 0.0125
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0038 0.0046 0.0933
Echinococcus granulosus death domain containing protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0234
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.027 0.0537 0.0536
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0004 0.0004
Echinococcus multilocularis protein dispatched 1 0.0054 0.0079 0.0079
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0034 0.0671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Trypanosoma cruzi Bromodomain, putative 0.0021 0.0011 0.0201
Trypanosoma cruzi Bromodomain, putative 0.0021 0.0011 0.0201
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0442 0.0899 0.0899
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.08 0.1654 0.1653
Toxoplasma gondii Hsp90 domain-containing protein 0.012 0.022 0.3791
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.003 0.0029 0.0189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0136 0.0254 0.0253
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Schistosoma mansoni metabotropic glutamate receptor 0.0118 0.0216 0.0216
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0022 0.0021
Onchocerca volvulus 0.0059 0.009 0.0375
Schistosoma mansoni phd finger protein 0.0021 0.0011 0.0011
Echinococcus multilocularis FTZ F1 alpha 0.0059 0.009 0.0089
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0041 0.0041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0059 0.0091 0.009
Schistosoma mansoni glutamate receptor NMDA 0.2689 0.564 0.564
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Brugia malayi hypothetical protein 0.0092 0.016 0.0573
Brugia malayi G protein-coupled receptor 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Brugia malayi Serotonin receptor 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0167 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0134 0.0249 0.0891
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0025 0.0024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0084 0.0143 0.0523
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0111 0.2308
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Schistosoma mansoni hypothetical protein 0.009 0.0156 0.0156
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0034 0.0269
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0031 0.0112
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis apoptosis inducing factor, putative 0.0022 0.0013 0.0037
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0041 0.0052 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0108 0.0431
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis Smad4 0.0073 0.0121 0.012
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0034 0.038
Echinococcus granulosus global transcription activator snf2l2 0.0021 0.0011 0.0011
Echinococcus granulosus serotonin transporter 0.0019 0.0006 0.0005
Mycobacterium ulcerans NADH dehydrogenase 0.0022 0.0013 0.0167
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0086 0.0699
Brugia malayi Dopamine receptor protein 1 0.0075 0.0125 0.0447
Schistosoma mansoni biogenic amine (5HT) receptor 0.0441 0.0897 0.0897
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0125 0.0125
Onchocerca volvulus 0.0075 0.0125 0.0523
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.002
Schistosoma mansoni methyl-cpg binding protein mbd 0.0125 0.023 0.023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni heat shock protein 0.0135 0.0251 0.0251
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0026 0.0022 0.0063
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0013 0.0244
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0053
Plasmodium vivax SET domain protein, putative 0.0145 0.0273 0.3074
Echinococcus granulosus transcription factor eb 0.0305 0.0609 0.0609
Trypanosoma brucei Bromodomain, putative 0.0021 0.0011 0.0086
Toxoplasma gondii cathepsin CPL 0.0018 0.0004 0.0063
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0022 0.0013 0.0104
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0059 0.009 0.009
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0011 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0072 0.0118 0.2452
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.003 0.0029 0.0029
Echinococcus multilocularis geminin 0.0836 0.1731 0.1731
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0013 0.0013
Brugia malayi Death domain containing protein 0.0018 0.0003 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0011 0.0203
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0125 0.0447
Toxoplasma gondii isocitrate dehydrogenase 0.0059 0.0091 0.155
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.0122
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0189 0.0365 0.0364
Entamoeba histolytica hypothetical protein 0.009 0.0156 0.1037
Echinococcus multilocularis glutamate receptor NMDA 0.1228 0.2557 0.2557
Echinococcus multilocularis cpg binding protein 0.0031 0.0031 0.0031
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0134 0.0249 0.5215
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.004 0.0052 0.0051
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0026 0.0022 0.0567
Echinococcus granulosus allatostatin A receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Loa Loa (eye worm) mbt repeat family protein 0.0116 0.0211 0.0755
Loa Loa (eye worm) RGC/RGC protein kinase 0.0118 0.0216 0.077
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0026 0.0022 0.0063
Brugia malayi Hsp90 protein 0.006 0.0094 0.0334
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0084 0.0143 0.1167
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0034 0.0276
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0036 0.0043 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0022 0.0428
Onchocerca volvulus 0.0167 0.0319 0.1332
Brugia malayi Thioredoxin reductase 0.0242 0.0477 0.1702
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0059 0.009 0.0321
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0064 0.0102 0.1146
Leishmania major NADH dehydrogenase, putative 0.0022 0.0013 0.0244
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.0167 0.0319 0.0319
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0026 0.0022 0.0291
Brugia malayi bromodomain containing protein 0.0021 0.0011 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0551 0.113 0.4272
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0013 0.0013
Loa Loa (eye worm) programmed cell death 8 0.0022 0.0013 0.0048
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0004 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0004 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0025 0.0025
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0022 0.1202
Brugia malayi nuclear receptor NHR-88 0.0028 0.0025 0.0088
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Schistosoma mansoni alpha-glucosidase 0.0136 0.0253 0.0253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Schistosoma mansoni cpg binding protein 0.0031 0.0031 0.0031
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) MH1 domain-containing protein 0.0073 0.0121 0.0432
Echinococcus multilocularis lamin dm0 0.0061 0.0095 0.0094
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0198 0.0385 0.144
Plasmodium vivax CDK-related protein kinase 6, putative 0.0436 0.0887 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus granulosus muscleblind protein 0.0227 0.0446 0.0445
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0125 0.0447
Mycobacterium leprae Probable two-component sensor kinase 0.0026 0.0022 0.0123
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0167 0.0318 0.3579
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0054 0.008 0.0287
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0084 0.0143 0.2459
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0043 0.0056 0.0056
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0034 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Echinococcus granulosus sodium and chloride dependent glycine 0.0096 0.0168 0.0167
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0441 0.0897 0.0896
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0125 0.0125
Plasmodium vivax multidomain scavenger receptor, putative 0.0167 0.0319 0.3592
Schistosoma mansoni hypothetical protein 0.0136 0.0254 0.0254
Loa Loa (eye worm) CBP-B 0.0021 0.0011 0.004
Trichomonas vaginalis glutaminase, putative 0.0341 0.0686 0.2851
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0013 0.0244
Leishmania major DNA polymerase kappa, putative 0.0057 0.0086 0.1776
Plasmodium vivax hexose transporter 0.0103 0.0183 0.2055
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0013 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.0059 0.009 0.0321
Plasmodium falciparum basic transcription factor 3b, putative 0.0075 0.0124 0.1394
Plasmodium falciparum thioredoxin reductase 0.0242 0.0477 0.5366
Giardia lamblia Hypothetical protein 0.0021 0.0011 0.0065
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0299 0.1068
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0263 0.0522 0.0521
Trichomonas vaginalis heat shock protein, putative 0.011 0.0199 0.0814
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0059 0.009 0.0089
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Trichomonas vaginalis D-aminoacylase, putative 0.0198 0.0385 0.1589
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0084 0.0143 0.7022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi jmjC domain containing protein 0.0134 0.0249 0.0891
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.003 0.0029 0.0029
Loa Loa (eye worm) PHD-finger family protein 0.0144 0.027 0.0964
Brugia malayi hypothetical protein 0.0025 0.0019 0.0067
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Brugia malayi Sugar transporter family protein 0.0103 0.0183 0.0654
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0004 0.0041
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0013 0.0244
Echinococcus multilocularis peregrin 0.0165 0.0315 0.0314
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0159 0.0301 0.1241
Echinococcus granulosus somatostatin receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.1461 0.3049 0.3049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0059 0.009 0.0089
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0011
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0177 0.0341 0.0341
Brugia malayi isocitrate dehydrogenase 0.0059 0.0091 0.0324
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Leishmania major heat shock protein, putative 0.006 0.0094 0.1933
Brugia malayi Protein kinase domain containing protein 0.002 0.0009 0.0033
Onchocerca volvulus 0.0476 0.0972 0.4054
Mycobacterium ulcerans two component sensor kinase MprB 0.0026 0.0022 0.0291
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis heat shock protein, putative 0.0059 0.009 0.0358
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Echinococcus granulosus ubiquitin specific protease 41 0.003 0.0029 0.0029
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0034 0.038
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0034 0.0269
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0026 0.0022 0.0291
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Trypanosoma cruzi Bromodomain factor 1 0.0021 0.0011 0.0201
Trypanosoma brucei NADH dehydrogenase 0.0022 0.0013 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0062 0.0096 0.0344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.0218 0.0892
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0022 0.0013 0.0037
Echinococcus multilocularis microtubule associated protein 2 0.4755 1 1
Loa Loa (eye worm) fibroinase 0.0018 0.0004 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.008 0.0287
Schistosoma mansoni endoplasmin 0.0135 0.0251 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0025 0.0024
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0013 0.0244
Echinococcus multilocularis ubiquitin specific protease 41 0.003 0.0029 0.0029
Echinococcus multilocularis histone acetyltransferase MYST2 0.0132 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0059 0.0091 0.1871
Schistosoma mansoni tar DNA-binding protein 0.003 0.003 0.003
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0021 0.0011 0.0047
Brugia malayi follicle stimulating hormone receptor 0.0331 0.0665 0.2374
Schistosoma mansoni hypothetical protein 0.0151 0.0285 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0124 0.0501
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0035 0.0041 0.004
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0201 0.0201
Treponema pallidum oxidoreductase 0.0022 0.0013 0.0054
Brugia malayi Uncoordinated protein 44 0.0018 0.0003 0.0012
Entamoeba histolytica protein kinase, putative 0.0032 0.0034 0.0205
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0021 0.0011 0.0029
Echinococcus granulosus dna polymerase kappa 0.0065 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0067
Loa Loa (eye worm) PHD-finger family protein 0.0151 0.0285 0.1019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0059 0.009 0.0321
Brugia malayi Importin beta-1 subunit 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0431 0.0876 0.3127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0125 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0108 0.0431
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0054 0.008 0.008
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.012 0.0219 0.3121
Leishmania major glucose transporter, lmgt3 0.0032 0.0034 0.0671
Echinococcus granulosus serine protein kinase ATM 0.0038 0.0046 0.0045
Loa Loa (eye worm) thioredoxin reductase 0.0242 0.0477 0.1702
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0125 0.0125
Onchocerca volvulus 0.0021 0.001 0.0041
Leishmania major DNA polymerase eta, putative 0.0027 0.0024 0.0475
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0501 0.1025 0.1024
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.0025 0.0024
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.0025 0.0024
Entamoeba histolytica 90 kDa heat shock protein, putative 0.006 0.0094 0.061
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0013 0.0244
Brugia malayi nuclear hormone receptor 0.0028 0.0025 0.0088
Mycobacterium tuberculosis Conserved protein 0.0198 0.0385 0.144
Trichomonas vaginalis endoplasmin, putative 0.0085 0.0146 0.0591
Leishmania major hypothetical protein, conserved 0.0112 0.0203 0.4236
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.004 0.0052 0.0051
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0189 0.0365 0.7644
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0084 0.0143 0.1167
Brugia malayi hypothetical protein 0.0019 0.0006 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0104 0.2149
Leishmania major hypothetical protein, conserved 0.0026 0.0022 0.0428
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0036 0.0127
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0011 0.0029
Entamoeba histolytica protein kinase rad3, putative 0.0038 0.0046 0.0285
Entamoeba histolytica hypothetical protein 0.0021 0.0011 0.0047
Schistosoma mansoni hypothetical protein 0.0047 0.0066 0.0066
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) glutamate receptor 2 0.1343 0.28 1
Schistosoma mansoni intermediate filament proteins 0.0061 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0062 0.0097 0.0346
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0002 0.0008
Giardia lamblia Hypothetical protein 0.0021 0.0011 0.0065
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0149 0.0281 0.028
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0022 0.0013 0.0053
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0022 0.0013 0.0079
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0198 0.0385 0.1374
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0022 0.1202
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0025 0.0088
Schistosoma mansoni smad 0.0073 0.0121 0.0121
Echinococcus multilocularis glutamate receptor 2 0.0959 0.1991 0.199
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0021 0.0011 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0072 0.0118 0.1324
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0189 0.0365 0.0364
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.0249 0.0891
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi tailless protein 0.0028 0.0025 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0059 0.009 0.0321
Plasmodium falciparum glutathione reductase 0.0084 0.0143 0.1606
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0006 0.0006
Brugia malayi mbt repeat family protein 0.0116 0.0211 0.0755
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0125 0.0447
Plasmodium falciparum DNA gyrase subunit B 0.0026 0.0022 0.024
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0125 0.0125
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0199 0.0387 0.3169
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.0006 0.0005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0004 0.0041
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0029 0.0028 0.0027
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0084 0.0143 0.2979
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.006 0.0094 0.039
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0022 0.0013 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0242 0.0477 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus atrial natriuretic peptide receptor 0.0118 0.0216 0.0215
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0059 0.009 0.0321
Echinococcus granulosus peregrin 0.0165 0.0315 0.0314
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0004 0.0004
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0083 0.0141 0.1152
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0036 0.0127
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0134 0.0249 0.0249
Echinococcus granulosus mothers against decapentaplegic 6 0.0033 0.0036 0.0035
Echinococcus granulosus single minded 2 0.002 0.0009 0.0008
Brugia malayi BRM protein 0.0021 0.0011 0.004
Onchocerca volvulus 0.0167 0.0319 0.1332
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.004 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0199 0.0387 0.1601
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0026 0.0022 0.0074
Echinococcus granulosus nmda type glutamate receptor 0.1748 0.3655 0.3654
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0189 0.0365 0.2983
Onchocerca volvulus 0.0018 0.0004 0.0019
Plasmodium vivax vivapain-2 0.0018 0.0004 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0022 0.024
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.011 0.0199 0.1535
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0029 0.0104
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0019 0.0007 0.0005
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0015 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0111 0.2308
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0116 0.0211 0.0882
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Toxoplasma gondii hypothetical protein 0.0019 0.0006 0.0084
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0124 0.2582
Loa Loa (eye worm) latrophilin receptor protein 2 0.0136 0.0254 0.0907
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0035 0.0041 0.0145
Schistosoma mansoni hypothetical protein 0.0136 0.0254 0.0254
Schistosoma mansoni tar DNA-binding protein 0.003 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0026 0.0022 0.0021
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Schistosoma mansoni fkbp-rapamycin associated protein 0.0038 0.0046 0.0046
Loa Loa (eye worm) acetyltransferase 0.0177 0.0341 0.1218
Brugia malayi mothers against decapentaplegic homolog 3 0.0033 0.0036 0.0127
Schistosoma mansoni hypothetical protein 0.0103 0.0183 0.0183
Loa Loa (eye worm) glutamate receptor 0.0118 0.0216 0.077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0025 0.0024
Plasmodium vivax amine transporter, putative 0.0019 0.0006 0.0055
Brugia malayi Glutamate receptor 2 precursor 0.1343 0.28 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0518 0.1059 0.3782
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0011 0.0181
Brugia malayi steroid hormone receptor 0.0059 0.009 0.0321
Trypanosoma brucei ISWI complex protein 0.0112 0.0203 0.1657
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0104 0.1465
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0022 0.0013 0.0053
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0104 0.0844
Entamoeba histolytica hypothetical protein 0.009 0.0156 0.1037
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0125 0.0125
Echinococcus granulosus heat shock protein 0.0135 0.0251 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Brugia malayi polybromodomain protein 0.0021 0.0011 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0028 0.0098
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0021 0.0011 0.0183
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.0025 0.0088
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0189 0.0365 0.0365
Schistosoma mansoni importin beta-1 0.0016 0.0001 0.0001
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0042 0.0851
Brugia malayi AF-10 protein 0.0047 0.0066 0.0234
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0125 0.0447
Brugia malayi Pre-SET motif family protein 0.0145 0.0273 0.0976
Schistosoma mansoni zinc finger protein 0.0028 0.0025 0.0025
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0026 0.0022 0.0113
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0013 0.0013
Trypanosoma brucei Bromodomain, putative 0.0021 0.0011 0.0086
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0167 0.0318 0.5478
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0026 0.0022 0.0291
Trichomonas vaginalis penicillin-binding protein, putative 0.0198 0.0385 0.1589
Echinococcus granulosus CREB binding protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0174 0.0333 0.119
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0026 0.0022 0.0567
Plasmodium vivax hypothetical protein, conserved 0.0144 0.027 0.3034
Echinococcus granulosus endoplasmin 0.011 0.0199 0.0198
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0011
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0122 0.0223 0.0798
Loa Loa (eye worm) doublecortin family protein 0.0167 0.0319 0.114
Entamoeba histolytica deoxycytidyl transferase, putative 0.0054 0.008 0.0519
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.0168 0.0168
Schistosoma mansoni single-minded 0.0027 0.0024 0.0024
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0034 0.0034
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0079
Echinococcus multilocularis serotonin receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Brugia malayi hypothetical protein 0.0031 0.0032 0.0113
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0095 0.034
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis General substrate transporter 0.0088 0.0153 0.0152
Echinococcus multilocularis heat shock protein 90 0.0109 0.0196 0.0195
Plasmodium vivax vivapain-2 0.0018 0.0004 0.0041
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0118 0.0216 0.0215
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0084 0.0143 0.2031
Brugia malayi Steroid receptor seven-up type 2 0.0059 0.009 0.0321
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0186
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0004 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Trypanosoma brucei Bromodomain, putative 0.0021 0.0011 0.0086
Loa Loa (eye worm) sugar transporter 0.0103 0.0183 0.0654
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0064 0.0102 0.0409
Onchocerca volvulus 0.0075 0.0125 0.0523
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0198 0.0385 0.1374
Schistosoma mansoni voltage-gated cation channel 0.004 0.0052 0.0052
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1461 0.3049 0.3049
Brugia malayi Receptor family ligand binding region containing protein 0.0118 0.0216 0.077
Loa Loa (eye worm) calpain family protein 1 0.0028 0.0027 0.0095
Trypanosoma brucei AAA ATPase, putative 0.0021 0.0011 0.0086
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0042 0.0467
Treponema pallidum fructose-bisphosphate aldolase 0.071 0.1465 1
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.0062
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0022 0.0367
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Brugia malayi F/Y-rich N-terminus family protein 0.0071 0.0117 0.0417
Trypanosoma cruzi DNA polymerase eta, putative 0.0065 0.0103 0.2128
Schistosoma mansoni hypothetical protein 0.0594 0.1221 0.1221
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0004 0.0004
Schistosoma mansoni myosin xvIII 0.0075 0.0125 0.0125
Onchocerca volvulus 0.0118 0.0216 0.09
Echinococcus granulosus mothers against decapentaplegic 5 0.0073 0.0121 0.012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.027 0.0537 0.0537
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Echinococcus granulosus lipoxygenase domain containing protein 0.0167 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0086
Schistosoma mansoni smad1 5 8 and 0.0073 0.0121 0.0121
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0125 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Echinococcus multilocularis heat shock protein 0.0135 0.0251 0.0251
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0134 0.0249 0.2038
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0073 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Schistosoma mansoni sex comb on midleg homolog 0.0116 0.0211 0.0211
Toxoplasma gondii target of rapamycin (TOR), putative 0.0148 0.028 0.4812
Brugia malayi kinase, mitochondrial precursor 0.0026 0.0022 0.0079
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0018 0.0003 0.0003
Brugia malayi Bromodomain containing protein 0.0554 0.1136 0.4057
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0021 0.0011 0.0011
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0004 0.0004
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0118 0.0216 0.077
Echinococcus granulosus intermediate filament protein 0.0061 0.0095 0.0094
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0022 0.0074
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0075 0.1549
Schistosoma mansoni CREB-binding protein 2 0.0021 0.0011 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0084 0.0143 0.2979
Treponema pallidum hypothetical protein 0.012 0.0219 0.1464
Schistosoma mansoni nuclear receptor 0.0028 0.0025 0.0025
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0851
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0034 0.0123
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0026 0.0022 0.0092
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0347 0.0698 0.2632
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0036 0.0043 0.0043
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0194 0.0791
Schistosoma mansoni coup transcription factor 0.0059 0.009 0.009
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0059 0.0091 0.0323
Schistosoma mansoni polycystin 1-related 0.0167 0.0319 0.0319
Echinococcus multilocularis Ankyrin 0.0018 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.0218 0.0892
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0199 0.0387 0.2622
Loa Loa (eye worm) calcium channel 0.004 0.0052 0.0185
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0059 0.009 0.0321
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0019 0.0006 0.0011
Trypanosoma cruzi Bromodomain, putative 0.0021 0.0011 0.0201
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0025 0.0103
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0054 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0197
Schistosoma mansoni hypothetical protein 0.0836 0.1731 0.1731
Echinococcus granulosus lysine specific demethylase 5A 0.0518 0.1059 0.1058
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0263 0.0522 0.0521
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.071 0.1465 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0199 0.0387 0.0387
Echinococcus multilocularis glutamate receptor 2 0.1343 0.28 0.2799
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.004 0.0052 0.0051
Brugia malayi ADAMTS-like protease 0.0027 0.0022 0.008
Onchocerca volvulus 0.0022 0.0012 0.0051
Onchocerca volvulus 0.0075 0.0125 0.0523
Brugia malayi Receptor family ligand binding region containing protein 0.0118 0.0216 0.077
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.004 0.0149
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.003 0.0029 0.0029
Entamoeba histolytica hypothetical protein 0.0075 0.0124 0.0821
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.003 0.0029 0.0584
Echinococcus multilocularis GPCR, family 2 0.0136 0.0254 0.0253
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0125 0.0125
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0242 0.0477 0.1789
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.004 0.081
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0013 0.0142
Trypanosoma cruzi heat shock protein 85, putative 0.0135 0.0251 0.5257
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0021 0.0011 0.0029
Onchocerca volvulus 0.0019 0.0006 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0034 0.0122
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0025 0.0019 0.0019
Echinococcus multilocularis transcription factor btf3 0.0075 0.0124 0.0124
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0075 0.1549
Schistosoma mansoni bromodomain containing protein 0.0021 0.0011 0.0011
Trypanosoma cruzi bromodomain-containing protein 3 0.0021 0.0011 0.0201
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0029 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0193 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0019 0.006
Echinococcus multilocularis glutamate synthase 0.0022 0.0013 0.0013
Onchocerca volvulus 0.0019 0.0006 0.0024
Brugia malayi Endoplasmin precursor 0.0135 0.0251 0.0898
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi MH1 domain containing protein 0.0041 0.0052 0.0186
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0034 0.0581
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0199 0.0387 0.8122
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0059 0.009 0.0321
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0021 0.0011 0.0201
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0003 0.0029
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0727 0.15 0.1499
Loa Loa (eye worm) calpain family protein 1 0.0041 0.0052 0.0186
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis polybromo 1 0.0021 0.0011 0.0011
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0043 0.0056 0.0056
Brugia malayi PHD-finger family protein 0.0144 0.027 0.0964
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Echinococcus multilocularis mothers against decapentaplegic 5 0.0073 0.0121 0.012
Schistosoma mansoni phd/f-box containing protein 0.0134 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0086 0.0149 0.0532
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0125 0.0125
Echinococcus granulosus metabotropic glutamate receptor 5 0.0118 0.0216 0.0215
Echinococcus granulosus smad 0.0073 0.0121 0.012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.004 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0016
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0197 0.1321
Brugia malayi jmjC domain containing protein 0.0518 0.1059 0.3782
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Echinococcus multilocularis netrin receptor unc 5 0.0018 0.0003 0.0003
Loa Loa (eye worm) ctsf protein 0.0018 0.0004 0.0016
Echinococcus multilocularis jumonji domain containing protein 0.02 0.0389 0.0388
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0004 0.0016
Echinococcus granulosus lamin dm0 0.0061 0.0095 0.0094
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0019 0.0361
Leishmania major cathepsin L-like protease 0.0069 0.0111 0.2308
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Brugia malayi ORL1-like opioid receptor 0.0075 0.0125 0.0447
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Brugia malayi RNA, U transporter 1 0.0046 0.0064 0.0229
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0015 0.0014
Echinococcus multilocularis sex peptide receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) heat shock protein 75 0.006 0.0094 0.0334
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0035 0.0126
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0011 0.0087
Schistosoma mansoni steroid hormone receptor ad4bp 0.0059 0.009 0.009
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Plasmodium vivax bromodomain protein, putative 0.0021 0.0011 0.0119
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.003 0.0029 0.0171
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0059 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Echinococcus granulosus adam 0.0025 0.0019 0.0018
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0034 0.0122
Onchocerca volvulus 0.0075 0.0125 0.0523
Schistosoma mansoni inositol monophosphatase 0.0021 0.0011 0.0011
Echinococcus multilocularis serotonin transporter 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0079
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.01
Mycobacterium ulcerans glutamate synthase subunit beta 0.0022 0.0013 0.0167
Schistosoma mansoni tyrosine kinase 0.0118 0.0216 0.0216
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0071
Echinococcus granulosus glutamate receptor subunit protein glur 0.0501 0.1025 0.1024
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0026 0.0022 0.0174
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0095
Trypanosoma brucei chrX additional, unordered contigs 0.0017 0.0002 0.0008
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Leishmania major cathepsin L-like protease 0.0018 0.0004 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0026 0.0022 0.0291
Brugia malayi hypothetical protein 0.0476 0.0972 0.347
Trypanosoma cruzi target of rapamycin kinase 3 0.0159 0.0302 0.6315
Schistosoma mansoni cellular tumor antigen P53 0.0345 0.0694 0.0694
Loa Loa (eye worm) transcription factor SMAD2 0.1076 0.2236 0.7987
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0002 0.0008
Leishmania major protein kinase, putative 0.0032 0.0034 0.0688
Schistosoma mansoni metabotropic glutamate receptor 0.0118 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0227 0.0446 0.1593
Trypanosoma brucei protein kinase, putative 0.0052 0.0075 0.0611
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0125 0.0125
Brugia malayi hypothetical protein 0.0028 0.0025 0.0088
Echinococcus multilocularis ecdysone induced protein 78C 0.0059 0.009 0.0089
Brugia malayi GnHR receptor homolog 0.0075 0.0125 0.0447
Echinococcus multilocularis tar DNA binding protein 0.003 0.003 0.0029
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0048 0.0068 0.0754
Echinococcus granulosus glutamate receptor 2 0.1461 0.3049 0.3049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Onchocerca volvulus 0.0075 0.0125 0.0523
Schistosoma mansoni SET domain protein 0.0021 0.001 0.001
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0067 0.0108 0.0107
Echinococcus multilocularis voltage dependent calcium channel 0.004 0.0052 0.0051
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0033 0.0037 0.2293
Trypanosoma brucei Heat shock protein 83, putative 0.0135 0.0251 0.2054
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0022 0.0013 0.0048
Treponema pallidum thioredoxin reductase (trxB) 0.0022 0.0013 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0033 0.0036 0.0127
Echinococcus granulosus hypothetical protein 0.0075 0.0125 0.0125
Schistosoma mansoni bromodomain containing 0.0021 0.0011 0.0011
Echinococcus multilocularis PHD finger protein rhinoceros 0.0144 0.027 0.0269
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0013 0.0061
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.004 0.0052 0.0051
Brugia malayi neuropeptide F receptor 0.0075 0.0125 0.0447
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0013 0.0244
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0042 0.0715
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0124 0.2582
Schistosoma mansoni alpha-glucosidase 0.0136 0.0253 0.0253
Brugia malayi intermediate filament protein 0.0061 0.0095 0.034
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0059 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.0062
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis heat shock protein 90 0.0135 0.0251 0.0251
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1461 0.3049 0.3049
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.004 0.0149
Schistosoma mansoni heat shock protein 0.006 0.0094 0.0094
Echinococcus granulosus fetal alzheimer antigen falz 0.0166 0.0317 0.0316
Loa Loa (eye worm) Smad1 0.0073 0.0121 0.0432
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0075 0.1549
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0347 0.0698 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0125 0.0125
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0166 0.0317 0.0317
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0012 0.0034
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0032 0.0034 0.0034
Entamoeba histolytica ankyrin repeat protein, putative 0.0021 0.0011 0.0047
Leishmania major glucose transporter, lmgt1 0.0032 0.0034 0.0671
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0122 0.0223 0.0798
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0047 0.0066 0.1119
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0058 0.0381
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0134 0.0249 0.4291
Schistosoma mansoni biogenic amine receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Loa Loa (eye worm) inositol-1 0.0021 0.0011 0.0041
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus metabotropic glutamate receptor 2 0.0118 0.0216 0.0215
Brugia malayi mbt repeat family protein 0.0116 0.0211 0.0755
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0189 0.0365 0.7644
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0035 0.0041 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.0249 0.0891
Echinococcus granulosus Bromodomain containing protein 0.0021 0.0011 0.0011
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0015 0.0187
Echinococcus granulosus heat shock protein 90 0.0135 0.0251 0.0251
Mycobacterium ulcerans esterase/lipase LipP 0.0198 0.0385 0.5495
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0034 0.038
Plasmodium vivax bromodomain protein, putative 0.0021 0.0011 0.0119
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0042 0.0055 0.0938
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0025 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0198 0.0385 0.0385
Plasmodium falciparum ferrodoxin reductase-like protein 0.0022 0.0013 0.0142
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0082 0.014 0.05
Schistosoma mansoni glutamate receptor kainate 0.1343 0.28 0.28
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0022 0.0013 0.0167
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0034 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0295 0.0588 0.0588
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Onchocerca volvulus 0.0075 0.0125 0.0523
Schistosoma mansoni cpg binding protein 0.0031 0.0031 0.0031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0059 0.009 0.009
Plasmodium vivax JmjC domain containing protein 0.0134 0.0249 0.2804
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0011 0.0029
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0034 0.0671
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0034 0.038
Brugia malayi jmjC domain containing protein 0.08 0.1654 0.5907
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0046 0.0174
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0125 0.0125
Giardia lamblia DINP protein human, muc B family 0.0057 0.0086 0.0576
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Brugia malayi jmjC domain containing protein 0.0134 0.0249 0.0891
Schistosoma mansoni glutamate receptor kainate 0.1343 0.28 0.28
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0125 0.0447
Schistosoma mansoni hypothetical protein 0.0706 0.1456 0.1456
Echinococcus multilocularis inositol monophosphatase 1 0.0021 0.0011 0.0011
Echinococcus granulosus bromodomain containing protein 8 0.0021 0.0011 0.0011
Schistosoma mansoni aryl hydrocarbon receptor 0.0029 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0299 0.1068
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0296
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0149 0.0281 0.028
Schistosoma mansoni thyroid hormone receptor 0.0059 0.009 0.009
Leishmania major hypothetical protein, conserved 0.0198 0.0385 0.8062
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0013 0.0244
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Echinococcus granulosus glutamate NMDA receptor subunit 0.2142 0.4487 0.4487
Loa Loa (eye worm) hypothetical protein 0.0295 0.0588 0.21
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0197 0.0197
Brugia malayi photoreceptor-specific nuclear receptor 0.0059 0.009 0.0321
Onchocerca volvulus 0.0082 0.014 0.0584
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0031 0.0113
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0013 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.009 0.0321
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0021 0.0011 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0145 0.0273 0.0273
Plasmodium falciparum mitogen-activated protein kinase 2 0.0167 0.0318 0.3579
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni hypothetical protein 0.0029 0.0028 0.0028
Entamoeba histolytica heat shock protein 90, putative 0.0135 0.0251 0.1691
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0029 0.0235
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.027 0.0537 0.0536
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0125 0.0125
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0064 0.0102 0.0409
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.004 0.081
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0022 0.0367
Schistosoma mansoni netrin receptor unc5 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0144 0.027 0.0964
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0067 0.0108 0.2229
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0075 0.0269
Brugia malayi metabotropic glutamate receptor type 2 0.0118 0.0216 0.077
Brugia malayi hypothetical protein 0.0167 0.0319 0.114
Plasmodium falciparum ataxin-2 like protein, putative 0.0072 0.0118 0.1324
Mycobacterium leprae Probable lipase LipE 0.0198 0.0385 0.3015
Brugia malayi polk-prov protein 0.0028 0.0025 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0059 0.009 0.0321
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.0006 0.0006
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0303 0.0606 0.2165
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0022 0.0013 0.0037
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.004 0.0052 0.0185
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.004 0.0144
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0004 0.0041
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0029 0.0028
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.008 0.1655
Echinococcus multilocularis lysine specific demethylase 6a 0.0134 0.0249 0.0249
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0125 0.0447
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1266 0.2638 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0013 0.0217
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0015 0.0241
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0022 0.0013 0.0013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0198 0.0385 0.144
Mycobacterium ulcerans putative regultory protein 0.0026 0.0022 0.0291
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni Smad4 0.0033 0.0036 0.0036
Echinococcus multilocularis endoplasmin 0.011 0.0199 0.0198
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0013 0.0037
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0094 0.0166 0.135
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni protein kinase 0.0032 0.0034 0.0034
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Plasmodium falciparum amino acid transporter, putative 0.0019 0.0006 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0262
Trichomonas vaginalis esterase, putative 0.0198 0.0385 0.1589
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0034 0.0125
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0125 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0059 0.0091 0.0736
Onchocerca volvulus 0.0091 0.0159 0.0662
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0013 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus multilocularis musashi 0.0061 0.0095 0.0094
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0086 0.0306
Loa Loa (eye worm) DR-78 0.0028 0.0025 0.0088
Schistosoma mansoni amine GPCR 0.0075 0.0125 0.0125
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0125 0.0125
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0198 0.0385 0.144
Schistosoma mansoni hypothetical protein 0.0032 0.0034 0.0034
Schistosoma mansoni amine GPCR 0.0075 0.0125 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0189 0.0365 0.7644
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0189 0.0365 0.2467
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0058 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0026 0.0022 0.0291
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Schistosoma mansoni rab6-interacting 0.0167 0.0319 0.0319
Loa Loa (eye worm) BRM protein 0.0021 0.0011 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0084 0.0143 0.2031
Schistosoma mansoni hypothetical protein 0.0501 0.1025 0.1025
Brugia malayi Pre-SET motif family protein 0.1012 0.2102 0.7507
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0025 0.0024
Schistosoma mansoni jumonji/arid domain-containing protein 0.0518 0.1059 0.1059
Schistosoma mansoni helicase 0.0021 0.0011 0.0011
Echinococcus multilocularis CREB binding protein 0.0021 0.0011 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0125 0.0125
Treponema pallidum sodium- and chloride- dependent transporter 0.0019 0.0006 0.0001
Mycobacterium tuberculosis Conserved protein 0.0198 0.0385 0.144
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni DNA topoisomerase II 0.0026 0.0022 0.0022
Onchocerca volvulus 0.0075 0.0125 0.0523
Onchocerca volvulus 0.0198 0.0385 0.1604
Echinococcus multilocularis bromodomain containing protein 8 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0048
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0084 0.0143 0.0142
Trypanosoma cruzi DNA polymerase eta, putative 0.0027 0.0024 0.0475
Trypanosoma cruzi heat shock protein 85, putative 0.0135 0.0251 0.5257
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0199 0.0387 0.0387
Onchocerca volvulus Huntingtin homolog 0.0371 0.075 0.3128
Echinococcus granulosus glutamate synthase 0.0022 0.0013 0.0013
Brugia malayi hypothetical protein 0.0403 0.0817 0.2919
Echinococcus multilocularis jumonji domain containing 1A 0.0134 0.0249 0.0249
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0501 0.1025 0.1024
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0013 0.0217
Brugia malayi MH1 domain containing protein 0.0073 0.0121 0.0432
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0125 0.0125
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0022 0.0013 0.003
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.0025 0.0024
Plasmodium vivax heat shock protein, putative 0.012 0.022 0.2477
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Leishmania major cathepsin L-like protease 0.0069 0.0111 0.2308
Giardia lamblia Heat shock protein HSP 90-alpha 0.0135 0.0251 0.1706
Loa Loa (eye worm) hypothetical protein 0.0302 0.0604 0.2159
Schistosoma mansoni opsin-like receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Brugia malayi hypothetical protein 0.0031 0.0032 0.0113
Toxoplasma gondii selenide, water dikinase 0.0022 0.0013 0.0217
Entamoeba histolytica hypothetical protein 0.0118 0.0216 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0194 0.0791
Trypanosoma cruzi Bromodomain, putative 0.0021 0.0011 0.0201
Schistosoma mansoni transcription factor LCR-F1 0.009 0.0156 0.0156
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0026 0.0022 0.024
Onchocerca volvulus 0.0075 0.0125 0.0523
Trypanosoma brucei transcription factor BTF3, putative 0.0075 0.0124 0.1013
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0015 0.0064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Loa Loa (eye worm) hypoxia-induced factor 1 0.0085 0.0145 0.0519
Brugia malayi angiogenesis inhibito 0.0027 0.0022 0.008
Echinococcus granulosus PHD finger protein rhinoceros 0.0144 0.027 0.0269
Onchocerca volvulus 0.0075 0.0125 0.0523
Leishmania major phosphatidylinositol 3-kinase, putative 0.0067 0.0108 0.2229
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0025 0.0018 0.0144
Echinococcus multilocularis beta LACTamase domain containing family member 0.0198 0.0385 0.0384
Loa Loa (eye worm) hypothetical protein 0.0167 0.0319 0.114
Mycobacterium ulcerans dehydrogenase 0.0022 0.0013 0.0167
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0125 0.0125
Brugia malayi nuclear receptor RXR 0.0028 0.0025 0.0088
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.004 0.0149
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Onchocerca volvulus 0.0075 0.0125 0.0523
Brugia malayi polybromodomain protein 0.0021 0.0011 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0124 0.0501
Mycobacterium ulcerans monoxygenase 0.0022 0.0013 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0104 0.2149
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0035 0.0126
Brugia malayi beta-NAC-like protein 0.0075 0.0124 0.0444
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni protein phosphatase 2C 0.0134 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0371 0.075 0.2678
Trypanosoma cruzi heat shock protein 90, putative 0.0076 0.0128 0.2651
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0125 0.0125
Echinococcus granulosus phd:f box containing protein 0.0134 0.0249 0.0249
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0011 0.0203
Brugia malayi RNA binding protein 0.003 0.003 0.0107
Echinococcus granulosus g protein coupled receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0015 0.0274
Schistosoma mansoni tar DNA-binding protein 0.003 0.003 0.003
Echinococcus granulosus survival motor neuron protein 1 0.0403 0.0817 0.0817
Loa Loa (eye worm) beta-lactamase 0.0198 0.0385 0.1374
Loa Loa (eye worm) MH2 domain-containing protein 0.1076 0.2236 0.7987
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0004 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.0212
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0013 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0022 0.0428
Echinococcus multilocularis Bromodomain containing protein 0.0021 0.0011 0.0011
Schistosoma mansoni glucose transport protein 0.0103 0.0183 0.0183
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0104 0.2149
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0022 0.0013 0.0217
Schistosoma mansoni hypothetical protein 0.0227 0.0445 0.0445
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0104 0.0844
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Schistosoma mansoni hypothetical protein 0.0075 0.0125 0.0125
Entamoeba histolytica disulphide oxidoreductase, putative 0.0022 0.0013 0.0061
Plasmodium falciparum JmjC domain-containing protein, putative 0.0134 0.0249 0.2804
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Plasmodium falciparum endoplasmin, putative 0.0085 0.0146 0.1635
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.004 0.081
Echinococcus multilocularis thyroid hormone receptor alpha 0.0059 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.009 0.0089
Schistosoma mansoni rab6-interacting 0.0167 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0031 0.0031
Echinococcus granulosus fmrfamide receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3194 0.6706 0.6706
Plasmodium vivax SET domain containing protein 0.0027 0.0023 0.0254
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0125 0.0125
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0303 0.0606 0.2165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0041 0.0041
Echinococcus granulosus glutamate receptor 2 0.0959 0.1991 0.199
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0125 0.0125
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.0125 0.0125
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0132 0.0245 0.0876
Echinococcus granulosus heat shock protein 90 0.0109 0.0196 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0026 0.0022 0.0291
Mycobacterium ulcerans heat shock protein 90 0.011 0.0199 0.2833
Brugia malayi glutamate synthase 0.0022 0.0013 0.0048
Onchocerca volvulus 0.0075 0.0125 0.0523
Loa Loa (eye worm) MBCTL1 0.0132 0.0245 0.0876
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0084 0.0143 0.1167
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0006 0.0006
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0122 0.0223 0.0223
Treponema pallidum heat shock protein 90 0.011 0.0199 0.1327
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0112 0.0203 0.0203
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0031 0.0112
Echinococcus multilocularis Polycystic kidney disease protein 0.0167 0.0319 0.0319
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0022 0.0013 0.003
Loa Loa (eye worm) bromodomain containing protein 0.0133 0.0248 0.0885
Brugia malayi Protein kinase domain containing protein 0.0122 0.0223 0.0798
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0021 0.0011 0.0011
Echinococcus multilocularis phd:f box containing protein 0.0134 0.0249 0.0249
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.004 0.0245
Plasmodium vivax DNA topoisomerase II, putative 0.0026 0.0022 0.024
Loa Loa (eye worm) RNA binding protein 0.003 0.003 0.0107
Echinococcus granulosus zinc finger protein 0.0148 0.0279 0.0278
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0034 0.038
Plasmodium vivax basic transcription factor 3b, putative 0.0075 0.0124 0.1394
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0059 0.009 0.0321
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0022 0.0013 0.0244
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.0025 0.0025
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0144 0.027 0.027
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.0112
Echinococcus granulosus transcription factor Dp 1 0.0109 0.0197 0.0196
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0022 0.0013 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0011 0.0119
Loa Loa (eye worm) hypothetical protein 0.0227 0.0446 0.1593
Echinococcus granulosus sodium and chloride dependent glycine 0.0096 0.0168 0.0167
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0021 0.0011 0.0011
Echinococcus multilocularis glutamate receptor 2 0.1461 0.3049 0.3049
Echinococcus granulosus g protein coupled receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Plasmodium vivax DNA repair protein REV1, putative 0.0017 0.0002 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0125 0.0125
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0026 0.0022 0.0063
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0038 0.0046 0.0371
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.071 0.1465 1
Schistosoma mansoni tar DNA-binding protein 0.003 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0317 0.0636 0.2271
Brugia malayi Guanylyl cyclase protein 23 0.0118 0.0216 0.077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Echinococcus multilocularis transfer RNA-Lys 0.002 0.0009 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni amine GPCR 0.1757 0.3675 0.3675
Leishmania major cathepsin L-like protease 0.0018 0.0004 0.0057
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0851
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0501 0.1025 0.1024
Echinococcus multilocularis lamin 0.0061 0.0095 0.0094
Brugia malayi calpain family protein 1 0.0041 0.0052 0.0186
Schistosoma mansoni disulfide oxidoreductase 0.0022 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0025 0.0103
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0075 0.0075
Loa Loa (eye worm) RGC/RGC protein kinase 0.0118 0.0216 0.077
Brugia malayi putative neuropeptide receptor 0.0075 0.0125 0.0447
Trypanosoma brucei unspecified product 0.0037 0.0045 0.0362
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0034 0.0671
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0022 0.0013 0.0048
Schistosoma mansoni glutamate synthase 0.0022 0.0013 0.0013
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0031 0.0031
Brugia malayi beta-lactamase 0.0198 0.0385 0.1374
Echinococcus granulosus JmjC domain containing protein 4 0.0134 0.0249 0.0249
Trypanosoma brucei developmentally regulated phosphoprotein 0.0026 0.0022 0.0174
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0059 0.009 0.0089
Schistosoma mansoni protein kinase 0.0032 0.0034 0.0034
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0013 0.003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0026 0.0022 0.0092
Loa Loa (eye worm) hypothetical protein 0.0518 0.106 0.3784
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0002 0.0008
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.0025 0.0024
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0075 0.0125 0.0125
Trichomonas vaginalis mercuric reductase, putative 0.0084 0.0143 0.058
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0125 0.0125
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0613 0.126 0.4766
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0011 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.009 0.0321
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0031 0.0032 0.0113
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0084 0.0143 0.1167
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni amine GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0125 0.0125
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0022 0.0013 0.0061
Mycobacterium tuberculosis Possible two component sensor kinase 0.0026 0.0022 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0025 0.0201
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0026 0.0022 0.0079
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0034 0.0581
Trypanosoma cruzi heat shock protein 90, putative 0.0109 0.0196 0.4085
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Giardia lamblia Kinase, putative 0.0021 0.0011 0.0065
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0034 0.0123
Onchocerca volvulus 0.0018 0.0004 0.0019
Trypanosoma cruzi hexose transporter 0.0032 0.0034 0.0671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.003 0.0029 0.0029
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0059 0.0091 0.1013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.027 0.0537 0.0537
Schistosoma mansoni neuropeptide receptor 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0334 0.0672 0.2398
Echinococcus granulosus dnaJ subfamily B 0.0227 0.0445 0.0444
Trypanosoma cruzi heat shock protein, putative 0.006 0.0094 0.1933
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0022 0.0013 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.004 0.0681
Schistosoma mansoni patched 1 0.0047 0.0065 0.0065
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0013 0.0048
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0061 0.0095 0.034
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Giardia lamblia Glutamate synthase 0.0022 0.0013 0.0079
Brugia malayi ecdysone receptor 0.0028 0.0025 0.0088
Plasmodium falciparum LCCL domain-containing protein 0.0167 0.0319 0.3592
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Plasmodium vivax endoplasmin, putative 0.0135 0.0251 0.2826
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis mothers against decapentaplegic 6 0.0033 0.0036 0.0035
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0062 0.0096 0.0344
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0118 0.0216 0.077
Brugia malayi Smad1 0.0073 0.0121 0.0432
Brugia malayi neuropeptide F receptor 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0013 0.0167
Brugia malayi nuclear receptor RXR 0.0031 0.0032 0.0113
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0013 0.0048
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.003 0.003 0.0107
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0059 0.009 0.0375
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0613 0.126 0.4766
Treponema pallidum NADH oxidase 0.0084 0.0143 0.0944
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.008 0.0284
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0022 0.0074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0059 0.009 0.0321
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0032 0.0113
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0145 0.0273 0.0273
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0084 0.0143 0.0142
Onchocerca volvulus 0.0075 0.0125 0.0523
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0022 0.0013 0.0013
Schistosoma mansoni jumonji domain containing protein 0.0134 0.0249 0.0249
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0197 0.0705
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0059 0.0091 0.1871
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0067 0.0108 0.2229
Brugia malayi MH2 domain containing protein 0.1076 0.2236 0.7987
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.012 0.0219 0.1695
Schistosoma mansoni tyrosine kinase 0.0118 0.0216 0.0216
Schistosoma mansoni zinc finger protein 0.0112 0.0203 0.0203
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0011 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0006 0.0055
Echinococcus granulosus lysine specific demethylase 6a 0.0134 0.0249 0.0249
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0043 0.0056 0.0056
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0104 0.1465
Schistosoma mansoni retinoic acid receptor RXR 0.0059 0.009 0.009
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0166 0.0317 0.0316
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.0112
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0125 0.0447
Plasmodium falciparum DNA repair protein REV1, putative 0.0017 0.0002 0.0011
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0013 0.0013
Echinococcus multilocularis global transcription activator snf2l2 0.0021 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Plasmodium falciparum phd finger protein, putative 0.0144 0.027 0.3034
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0013 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0059 0.009 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0108 0.0431
Echinococcus multilocularis expressed conserved protein 0.0103 0.0183 0.0183
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Brugia malayi PHD-finger family protein 0.0187 0.0362 0.1292
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0022 0.0074
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0017 0.0003 0.0002
Echinococcus granulosus Polycystic kidney disease protein 0.0167 0.0319 0.0319
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0059 0.009 0.0089
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0034 0.0122
Schistosoma mansoni alpha glucosidase 0.0035 0.004 0.004
Plasmodium falciparum bromodomain protein 2, putative 0.0021 0.0011 0.0119
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis cysteine protease 0.0018 0.0004 0.0004
Brugia malayi hypothetical protein 0.009 0.0156 0.0557
Echinococcus multilocularis bromodomain containing 2 0.0021 0.0011 0.0011
Plasmodium vivax thioredoxin reductase, putative 0.0242 0.0477 0.5366
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0132 0.0245 0.0245
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0015 0.0115
Echinococcus granulosus snurportin 1 0.0174 0.0333 0.0332
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0105
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0059 0.0091 0.1871
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0015 0.0043
Echinococcus granulosus sex peptide receptor 0.0075 0.0125 0.0125
Echinococcus granulosus ecdysone induced protein 78C 0.0059 0.009 0.0089
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0034 0.0269
Echinococcus multilocularis tyrosine kinase 0.0118 0.0216 0.0215
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0026 0.0022 0.0063
Brugia malayi Dopamine receptor protein 2 0.0075 0.0125 0.0447
Toxoplasma gondii PHD-finger domain-containing protein 0.0144 0.027 0.4644
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Mycobacterium tuberculosis Probable lipase LipD 0.0198 0.0385 0.144
Entamoeba histolytica heat shock protein 90, putative 0.0135 0.0251 0.1691
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Trypanosoma cruzi PAB1-binding protein , putative 0.0072 0.0118 0.2452
Echinococcus granulosus voltage dependent calcium channel 0.004 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0093 0.0331
Brugia malayi Glutamate receptor 1 precursor 0.1343 0.28 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.011 0.0199 0.0735
Brugia malayi CHE-14 protein 0.0047 0.0065 0.0234
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0111 0.2308
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0059 0.009 0.0089
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0067 0.0108 0.0108
Brugia malayi PHD-finger family protein 0.0062 0.0097 0.0346
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0125 0.0125
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0305 0.0609 0.2177
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0026 0.0022 0.0428
Echinococcus multilocularis isocitrate dehydrogenase 0.0059 0.0091 0.009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0199 0.0387 0.8122
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.006 0.0094 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0035 0.0041 0.004
Echinococcus granulosus biogenic amine 5HT receptor 0.0441 0.0897 0.0896
Onchocerca volvulus 0.0022 0.0013 0.0056
Brugia malayi glutathione reductase 0.0242 0.0477 0.1702
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.0025 0.0088
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1461 0.3049 0.3049
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0068 0.0754
Toxoplasma gondii heat shock protein HSP90 0.0135 0.0251 0.4326
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0084 0.0143 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0084 0.0143 0.7022
Echinococcus granulosus tumor protein p63 0.2355 0.4937 0.4937
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0011 0.004
Mycobacterium tuberculosis Probable reductase 0.0551 0.113 0.4272
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi Bromodomain containing protein 0.0165 0.0315 0.1124
Echinococcus multilocularis sodium and chloride dependent glycine 0.0096 0.0168 0.0167
Giardia lamblia Fructose-bisphosphate aldolase 0.071 0.1465 1
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.027 0.0537 0.1918
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Loa Loa (eye worm) ICD-1 protein 0.0075 0.0124 0.0444
Schistosoma mansoni hypothetical protein 0.0075 0.0125 0.0125
Schistosoma mansoni glutamate receptor AMPA 0.1343 0.28 0.28
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0011 0.0181
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0136 0.0254 0.0253
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0067 0.0108 0.0876
Trypanosoma brucei DNA topoisomerase ii 0.0026 0.0022 0.0174
Entamoeba histolytica hypothetical protein 0.009 0.0156 0.1037
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0013 0.0037
Giardia lamblia Thioredoxin reductase 0.0022 0.0013 0.0079
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0021 0.0011 0.0181
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0199 0.0387 0.8122
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni lipoxygenase 0.0426 0.0865 0.0865
Onchocerca volvulus 0.0028 0.0025 0.0103
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Plasmodium falciparum thioredoxin reductase 0.0084 0.0143 0.1606
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0199 0.0387 0.3169
Brugia malayi hypothetical protein 0.0371 0.075 0.2678
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0026 0.0022 0.0063
Brugia malayi MH2 domain containing protein 0.0073 0.0121 0.0432
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0026 0.0022 0.0074
Onchocerca volvulus 0.0028 0.0025 0.0103
Onchocerca volvulus 0.0061 0.0095 0.0397
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.012 0.0219 0.2463
Schistosoma mansoni hypothetical protein 0.0144 0.027 0.027
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0059 0.0091 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Toxoplasma gondii NADPH-glutathione reductase 0.0084 0.0143 0.2459
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.041
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0727 0.15 0.1499
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0026 0.0022 0.0021
Brugia malayi MH1 domain containing protein 0.0073 0.0121 0.0432
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0059 0.0091 0.0091
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0059 0.0091 0.1013
Onchocerca volvulus Huntingtin homolog 0.0371 0.075 0.3128
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0022 0.0074
Plasmodium vivax DNA gyrase subunit B, putative 0.0026 0.0022 0.024
Schistosoma mansoni glutamate receptor NMDA 0.2142 0.4487 0.4487
Brugia malayi beta-lactamase family protein 0.0198 0.0385 0.1374
Plasmodium falciparum hexose transporter 0.0103 0.0183 0.2055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0059 0.009 0.0321
Plasmodium falciparum DNA topoisomerase 2 0.0026 0.0022 0.024
Loa Loa (eye worm) glutathione reductase 0.0242 0.0477 0.1702
Brugia malayi Serotonin receptor 0.0075 0.0125 0.0447
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0118 0.0216 0.077
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0125 0.0447
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0022 0.0174
Entamoeba histolytica protein kinase, putative 0.0032 0.0034 0.0205
Echinococcus granulosus RUN 0.0167 0.0319 0.0319
Brugia malayi SET domain containing protein 0.0021 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0159 0.0301 0.1241
Echinococcus multilocularis 0.0021 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0082 0.014 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Echinococcus granulosus geminin 0.0836 0.1731 0.1731
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0136 0.0254 0.0907
Plasmodium vivax hypothetical protein, conserved 0.0198 0.0385 0.4329
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0198 0.0385 0.5495
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0072 0.0118 0.0422
Schistosoma mansoni smad1 5 8 and 0.0073 0.0121 0.0121
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0002 0.0008
Echinococcus multilocularis tumor protein p63 0.2355 0.4937 0.4937
Loa Loa (eye worm) hypothetical protein 0.0096 0.0168 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0193 0.079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0136 0.0254 0.0253
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0331 0.0665 0.2374
Loa Loa (eye worm) nuclear factor I 0.0041 0.0052 0.0186
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0013 0.0103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Echinococcus multilocularis snurportin 1 0.0174 0.0333 0.0332
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0004 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni tar DNA-binding protein 0.003 0.003 0.003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0244 0.0481 0.048
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Toxoplasma gondii NAC domain-containing protein 0.0075 0.0124 0.2133
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0021 0.0011 0.0119
Loa Loa (eye worm) hypothetical protein 0.0476 0.0972 0.347
Onchocerca volvulus 0.0075 0.0125 0.0523
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0199 0.0387 0.2622
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0022 0.0013 0.0142
Echinococcus granulosus methyl CpG binding domain protein 2 0.0125 0.023 0.0229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0032 0.0032
Trichomonas vaginalis glutathione reductase, putative 0.0084 0.0143 0.058
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0084 0.0143 0.2979
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0007 0.0008
Leishmania major developmentally regulated phosphoprotein-like protein 0.0026 0.0022 0.0428
Schistosoma mansoni thyroid hormone receptor 0.0059 0.009 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0025 0.0201
Loa Loa (eye worm) hypothetical protein 0.0116 0.0211 0.0755
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0012 0.0034
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0125 0.0125
Schistosoma mansoni zinc finger protein 0.0148 0.0279 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0108 0.0431
Trichomonas vaginalis DNA polymerase eta, putative 0.0065 0.0104 0.0415
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0125 0.0125
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0031 0.0203
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0189 0.0365 0.1302
Loa Loa (eye worm) hypothetical protein 0.0109 0.0197 0.0705
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0013 0.0167
Brugia malayi Doublecortin family protein 0.0167 0.0319 0.114
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0022 0.0013 0.0217
Echinococcus multilocularis receptor type guanylyl cyclase 0.0118 0.0216 0.0215
Trichomonas vaginalis penicillin-binding protein, putative 0.0198 0.0385 0.1589
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0084 0.0143 0.1606
Leishmania major DNA topoisomerase ii 0.0026 0.0022 0.0428
Onchocerca volvulus 0.0018 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0245 0.0484 0.173
Echinococcus granulosus General substrate transporter 0.0088 0.0153 0.0152
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0029 0.0028 0.0027
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0025 0.0088
Echinococcus granulosus dna polymerase eta 0.0065 0.0103 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni transcription initiation factor tfiid 0.0021 0.0011 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1461 0.3049 0.3049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Brugia malayi MH2 domain containing protein 0.0073 0.0121 0.0432
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Brugia malayi hypoxia-induced factor 1 0.0085 0.0145 0.0519
Loa Loa (eye worm) hypothetical protein 0.0403 0.0817 0.2919
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0026 0.0022 0.0063
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.0084
Echinococcus multilocularis somatostatin receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0132 0.0245 0.0245
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.004 0.0149
Echinococcus granulosus neuropeptide receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0038 0.0046 0.0045
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0244
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Leishmania major cathepsin L-like protease 0.0018 0.0004 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.0249 0.0891
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0125 0.0125
Trypanosoma cruzi Bromodomain, putative 0.0021 0.0011 0.0201
Loa Loa (eye worm) phosphatidylinositol 3 0.0199 0.0387 0.1384
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0118 0.0216 0.0215
Trichomonas vaginalis set domain proteins, putative 0.1152 0.2397 1
Onchocerca volvulus Papilin homolog 0.0027 0.0024 0.01
Echinococcus multilocularis sodium channel protein 0.0017 0.0003 0.0002
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus expressed conserved protein 0.0103 0.0183 0.0183
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0125 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0065 0.0255
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.004 0.0149
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0065 0.0065
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0075 0.0503
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0065 0.0104 0.0415
Giardia lamblia PHD finger protein 15 0.0144 0.027 0.1832
Schistosoma mansoni Smad4 0.0073 0.0121 0.0121
Loa Loa (eye worm) MH2 domain-containing protein 0.0073 0.0121 0.0432
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.0218 0.0892
Trichomonas vaginalis heat shock protein, putative 0.0135 0.0251 0.1032
Trichomonas vaginalis heat shock protein, putative 0.0109 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0109 0.0196 0.0195
Schistosoma mansoni glucose transport protein 0.0103 0.0183 0.0183
Echinococcus granulosus FTZ F1 alpha 0.0059 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.002
Schistosoma mansoni sodium/chloride dependent transporter 0.0098 0.0174 0.0174
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0299 0.0298
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0034 0.0122
Echinococcus granulosus polycomb protein SCMH1 0.0116 0.0211 0.0211
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0022 0.0013 0.0167
Toxoplasma gondii heat shock protein 90, putative 0.0135 0.0251 0.4326
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0015 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Brugia malayi hypothetical protein 0.0167 0.0319 0.114
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0125 0.0125
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0457 0.0932 0.0931
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0022 0.0013 0.0061
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Schistosoma mansoni glutamate synthase 0.0022 0.0013 0.0013
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0096 0.0168 0.06
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0013 0.0103
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0125 0.0125
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Giardia lamblia Transcription regulatory protein SNF2 0.0021 0.0011 0.0065
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0064 0.0102 0.1754
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0022 0.0013 0.0013
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.0025 0.0088
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0043 0.0056 0.0056
Brugia malayi Dopamine receptor 0.0075 0.0125 0.0447
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.0002 0.0017
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0022 0.0021
Loa Loa (eye worm) TOPoisomerase family member 0.0026 0.0022 0.0079
Loa Loa (eye worm) TAR-binding protein 0.003 0.003 0.0107
Brugia malayi hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi hypothetical protein 0.0245 0.0484 0.173
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.006 0.0094 0.0093
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0095 0.034
Schistosoma mansoni smad 0.0033 0.0036 0.0036
Plasmodium vivax ferrodoxin reductase, putative 0.0022 0.0013 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.0385 0.8062
Chlamydia trachomatis thioredoxin reductase 0.0022 0.0013 0.057
Echinococcus granulosus nmda type glutamate receptor 0.1346 0.2807 0.2806
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0159 0.0302 0.2466
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0125 0.0125
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0086 0.1776
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0031 0.0185
Schistosoma mansoni lamin 0.0061 0.0095 0.0095
Brugia malayi RE15519p 0.0075 0.0125 0.0447
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0095
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Onchocerca volvulus 0.0145 0.0273 0.114
Brugia malayi bHLH-PAS transcription factor 0.002 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis calpain A 0.0043 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0013 0.0053
Brugia malayi glutaminase DH11.1 0.0341 0.0686 0.2452
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0215 0.0882
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0038 0.0046 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis zinc finger protein 0.0148 0.0279 0.0278
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0022 0.0013 0.003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.009 0.0321
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1012 0.2102 0.7507
Trypanosoma brucei glucosidase, putative 0.0035 0.004 0.0323
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0031 0.0032 0.0031
Leishmania major mitochondrial DNA topoisomerase II 0.0026 0.0022 0.0428
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0004 0.0004
Trypanosoma brucei heat shock protein 84, putative 0.006 0.0094 0.076
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi FAT domain containing protein 0.0029 0.0028 0.01
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0125 0.0523
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0085 0.0085
Onchocerca volvulus Brd8 homolog 0.0021 0.0011 0.0047
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0022 0.0428
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0022 0.0013 0.0244
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.012 0.0219 0.0812
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0022 0.0013 0.0013
Plasmodium falciparum bromodomain protein 1 0.0021 0.0011 0.0119
Giardia lamblia NADH oxidase lateral transfer candidate 0.0084 0.0143 0.0967
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0006 0.0084
Brugia malayi hypothetical protein 0.0046 0.0064 0.023
Schistosoma mansoni bromodomain containing protein 0.0468 0.0955 0.0955
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Leishmania major hypothetical protein, conserved 0.0134 0.0249 0.5215
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0125 0.0447
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0186
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0075 0.1287
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0125 0.0125
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0022 0.0013 0.0053
Brugia malayi nuclear hormone receptor 0.0059 0.009 0.0321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.028 0.115
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.011 0.0199 0.4156
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0125 0.0125
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0197 0.0197
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0036 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0022 0.0428
Schistosoma mansoni RAR-like nuclear receptor 0.0059 0.009 0.009
Trypanosoma brucei unspecified product 0.0062 0.0098 0.0796
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0035 0.0041 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0019 0.006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0025 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.009 0.0321
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0134 0.0249 0.4291
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0011
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0034 0.0671
Echinococcus multilocularis smad 0.0073 0.0121 0.012
Trypanosoma brucei unspecified product 0.0037 0.0045 0.0362
Schistosoma mansoni Smad4 0.0033 0.0036 0.0036
Plasmodium falciparum protein kinase 7 0.0291 0.058 0.6534
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0026 0.0022 0.0174
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Brugia malayi MAP kinase sur-1 0.0052 0.0075 0.0269
Schistosoma mansoni terminal deoxycytidyl transferase 0.0054 0.008 0.008
Brugia malayi Muscleblind-like protein 0.0227 0.0446 0.1593
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0059 0.0091 0.009
Echinococcus multilocularis RUN 0.0167 0.0319 0.0319
Leishmania major cathepsin L-like protease 0.0018 0.0004 0.0057
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0084 0.0143 0.1606
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0084 0.0143 0.0143
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0067 0.0108 0.2229
Brugia malayi ImpB/MucB/SamB family protein 0.0065 0.0103 0.0367
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0067 0.0108 0.0384
Entamoeba histolytica hypothetical protein 0.0038 0.0046 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0159 0.0301 0.1241
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0031 0.0197
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.011 0.0199 1
Mycobacterium tuberculosis Conserved protein 0.0198 0.0385 0.144
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0125 0.0125
Onchocerca volvulus 0.0245 0.0484 0.2021
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0029 0.0028
Echinococcus multilocularis transcription factor Dp 1 0.0109 0.0197 0.0196
Trypanosoma brucei glucose transporter, putative 0.0032 0.0034 0.0269
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Onchocerca volvulus 0.0118 0.0216 0.09
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Brugia malayi PAS domain containing protein 0.0027 0.0024 0.0087
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0347 0.0698 0.5519
Onchocerca volvulus Protein ultraspiracle homolog 0.0059 0.009 0.0375
Echinococcus granulosus cathepsin l1 0.0018 0.0004 0.0004
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0177 0.0341 0.034
Onchocerca volvulus 0.0018 0.0004 0.0019
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0059 0.009 0.0089
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0096 0.0168 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0046 0.0174
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0046 0.0164
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.009 0.0156 0.0155
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0199 0.0387 0.1384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni heat shock protein 0.0135 0.0251 0.0251
Plasmodium vivax glutathione reductase, putative 0.0242 0.0477 0.5366
Onchocerca volvulus 0.0021 0.0011 0.0047
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0032 0.0113
Leishmania major hypothetical protein, conserved 0.0021 0.0011 0.0201
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0501 0.1025 0.1024
Echinococcus granulosus tar DNA binding protein 0.003 0.003 0.0029
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0021 0.0011 0.0011
Echinococcus multilocularis SAM and MBT domain containing protein 0.0116 0.0211 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0029 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0011 0.0201
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0011 0.0029
Trypanosoma brucei DNA polymerase eta, putative 0.0065 0.0103 0.0836
Echinococcus multilocularis sodium and chloride dependent glycine 0.0096 0.0168 0.0167
Mycobacterium leprae Probable two component sensor kinase MprB 0.0026 0.0022 0.0123
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0026 0.0022 0.0063
Brugia malayi Probable DNA topoisomerase II 0.0026 0.0022 0.0079
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0013 0.0103
Brugia malayi AKH receptor 0.0075 0.0125 0.0447
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0059 0.009 0.0321
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.0168 0.06
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0159 0.0302 0.6315
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0075 0.0611
Plasmodium falciparum transporter, putative 0.0019 0.0006 0.0055
Echinococcus granulosus beta LACTamase domain containing family member 0.0198 0.0385 0.0384
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.004 0.0052 0.0051
Echinococcus multilocularis protein patched 0.0047 0.0065 0.0065
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.004 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis cysteine protease 0.0018 0.0004 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0297 0.0593 0.2117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0104 0.2149
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0551 0.113 0.4272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.004
Toxoplasma gondii hypothetical protein 0.0021 0.0011 0.0181
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0321
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0026 0.0022 0.0021
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0171 0.0328 0.0327
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0059 0.0091 0.009
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.2142 0.4487 0.4487
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0022 0.0013 0.003
Toxoplasma gondii isocitrate dehydrogenase 0.0059 0.0091 0.155
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0034 0.038
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0125 0.0125
Echinococcus granulosus neuropeptide s receptor 0.0596 0.1223 0.1223
Giardia lamblia Grp94/Hsp90 0.011 0.0199 0.1349
Brugia malayi MH1 domain containing protein 0.0041 0.0052 0.0186
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0015 0.0274
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0551 0.113 0.4272
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0339
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0029 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni opsin-like receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0108 0.0431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0035 0.0041 0.004
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0084 0.0143 0.1606
Mycobacterium ulcerans glutaminase 0.0341 0.0686 0.9829
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0015 0.0015
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0038 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0065 0.0103 0.0367
Echinococcus granulosus calpain A 0.0043 0.0056 0.0056
Mycobacterium ulcerans DNA gyrase subunit B 0.0026 0.0022 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0046 0.0174
Echinococcus granulosus histone acetyltransferase MYST2 0.0132 0.0245 0.0245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0136 0.0254 0.0253
Trypanosoma brucei Bromodomain factor 1 0.0021 0.0011 0.0086
Loa Loa (eye worm) solute carrier family 6 member 4 0.0019 0.0006 0.002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0067 0.0108 0.0107
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0047 0.0066 0.0531
Schistosoma mansoni lozenge 0.0031 0.0031 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Plasmodium falciparum heat shock protein 90, putative 0.012 0.022 0.2477
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0013
Echinococcus multilocularis lipoxygenase domain containing protein 0.0167 0.0319 0.0319
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.0006 0.0005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.0025 0.0088
Schistosoma mansoni hypothetical protein 0.0022 0.0013 0.0013
Trypanosoma brucei RNA helicase, putative 0.0594 0.1221 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0501 0.1025 0.1024
Schistosoma mansoni ankyrin 23/unc44 0.0018 0.0003 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0198 0.0385 0.3015
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni opsin-like receptor 0.0075 0.0125 0.0125
Plasmodium vivax heat shock protein 90, putative 0.006 0.0094 0.1046
Mycobacterium tuberculosis Probable lipase LipE 0.0198 0.0385 0.144
Onchocerca volvulus 0.0018 0.0004 0.0019
Onchocerca volvulus 0.0075 0.0125 0.0523
Echinococcus granulosus lipoxygenase domain containing protein 0.0167 0.0319 0.0319
Echinococcus granulosus Ankyrin 0.0018 0.0004 0.0003
Schistosoma mansoni glutamate receptor kainate 0.1343 0.28 0.28
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0003
Trypanosoma brucei trypanothione reductase 0.0242 0.0477 0.39
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Loa Loa (eye worm) hypothetical protein 0.0058 0.0088 0.0314
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0022 0.0013 0.0167
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.08 0.1654 0.1653
Onchocerca volvulus 0.0075 0.0125 0.0523
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0189 0.0365 0.1302
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0199 0.0387 0.0387
Loa Loa (eye worm) phosphatidylinositol 3 0.0067 0.0108 0.0384
Echinococcus granulosus Smad4 0.0073 0.0121 0.012
Schistosoma mansoni nuclear receptor 0.0028 0.0025 0.0025
Schistosoma mansoni methyl-cpg binding protein mbd 0.0125 0.023 0.023
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.0295 0.0294
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0073 0.0121 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Echinococcus granulosus jumonji domain containing protein 0.02 0.0389 0.0388
Onchocerca volvulus 0.0019 0.0006 0.0024
Brugia malayi ecdysteroid receptor 0.0059 0.009 0.0321
Leishmania major trypanothione reductase 0.0242 0.0477 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus nuclear factor of activated T cells 5 0.0171 0.0328 0.0327
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0007 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0111 0.2308
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0059 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0004 0.0004
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0026 0.0022 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.0025 0.0024
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0032 0.0034 0.0034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0118 0.0216 0.077
Echinococcus granulosus CREB binding protein 0.0021 0.0011 0.0011
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0299 0.0298
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0125 0.0125
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.0039 0.0429
Echinococcus multilocularis muscleblind protein 1 0.0227 0.0446 0.0445
Echinococcus multilocularis dnaJ subfamily B 0.0227 0.0445 0.0444
Echinococcus multilocularis Bromodomain containing protein 0.0021 0.0011 0.0011
Schistosoma mansoni jumonji domain containing protein 0.0703 0.145 0.145
Trypanosoma cruzi heat shock protein 85, putative 0.0135 0.0251 0.5257
Brugia malayi heat shock protein 90 0.0135 0.0251 0.0898
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0022 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0136 0.0254 0.0254
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0022 0.0013 0.0167
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0125 0.0125
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0122 0.0223 0.0932
Brugia malayi hypothetical protein 0.0072 0.0118 0.0422
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0067 0.0108 0.0876
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0042 0.0467
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0034 0.0122
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis serine protein kinase ATM 0.0038 0.0046 0.0045
Onchocerca volvulus 0.0075 0.0125 0.0523
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0095 0.034
Echinococcus multilocularis protein kinase C binding protein 1 0.0021 0.0011 0.0011
Schistosoma mansoni neuropeptide receptor 0.0075 0.0125 0.0125
Plasmodium falciparum protein kinase 6 0.0436 0.0887 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Schistosoma mansoni lamin 0.0061 0.0095 0.0095
Echinococcus multilocularis neuropeptide receptor A26 0.0596 0.1223 0.1223
Brugia malayi Melatonin receptor type 1A 0.0075 0.0125 0.0447
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0031 0.0031
Echinococcus granulosus GPCR family 2 0.0136 0.0254 0.0253
Leishmania major DNA polymerase eta, putative 0.0065 0.0103 0.2128
Plasmodium falciparum glutathione reductase 0.0242 0.0477 0.5366
Entamoeba histolytica thioredoxin reductase, putative 0.0022 0.0013 0.0061
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0031 0.0032 0.0032
Schistosoma mansoni loxhd1 0.0167 0.0319 0.0319
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.0167
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0064 0.0102 0.1754
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0084 0.0143 0.2979
Schistosoma mansoni survival motor neuron protein 0.0082 0.014 0.014
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0551 0.113 0.4272
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0125 0.0125
Plasmodium falciparum bromodomain protein, putative 0.0021 0.0011 0.0119
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0199 0.0387 0.8122
Onchocerca volvulus 0.0018 0.0004 0.0019
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis heat shock protein, putative 0.0085 0.0146 0.0591
Trypanosoma cruzi heat shock protein 85, putative 0.0109 0.0196 0.4085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0075 0.1549
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0069
Onchocerca volvulus 0.0028 0.0027 0.0111
Echinococcus multilocularis nmda type glutamate receptor 0.1346 0.2807 0.2806
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni hypothetical protein 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0199 0.0387 0.1601
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0431 0.0876 0.3127
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0013 0.0061
Plasmodium falciparum heat shock protein 90, putative 0.0059 0.009 0.1008
Mycobacterium ulcerans lipase LipD 0.0198 0.0385 0.5495
Echinococcus granulosus bromodomain containing 2 0.0021 0.0011 0.0011
Echinococcus multilocularis PH interacting protein 0.0021 0.0011 0.0011
Echinococcus multilocularis voltage dependent calcium channel 0.004 0.0052 0.0051
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0013 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0295 0.0588 0.21
Onchocerca volvulus 0.0021 0.0011 0.0047
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0006 0.002
Echinococcus granulosus glutamate receptor NMDA 0.1228 0.2557 0.2557
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.0005 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi Bromodomain containing protein 0.0021 0.0011 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Trypanosoma brucei PAB1-binding protein , putative 0.0072 0.0118 0.0962
Mycobacterium tuberculosis Conserved protein 0.0026 0.0022 0.0063
Trypanosoma brucei glucose transporter 2A 0.0032 0.0034 0.0269
Echinococcus multilocularis Protein lozenge 0.0031 0.0031 0.0031
Toxoplasma gondii LsmAD domain-containing protein 0.0072 0.0118 0.2027
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.0025 0.0024
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0024 0.0406
Echinococcus granulosus jumonji domain containing 1A 0.0134 0.0249 0.0249
Trichomonas vaginalis DNA topoisomerase II, putative 0.0026 0.0022 0.0074
Brugia malayi MH2 domain containing protein 0.0033 0.0036 0.0127
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Brugia malayi Isocitrate dehydrogenase 0.0059 0.0091 0.0324
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0125 0.0125
Echinococcus granulosus neuropeptide receptor 0.0075 0.0125 0.0125
Brugia malayi ATPase, AAA family protein 0.0021 0.0011 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0079 0.0313
Loa Loa (eye worm) hypothetical protein 0.0198 0.0385 0.1374
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0015 0.0673
Toxoplasma gondii FATC domain-containing protein 0.0038 0.0046 0.0781
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0125 0.0125
Schistosoma mansoni myelin transcription factor 1 myt1 0.0132 0.0245 0.0245
Schistosoma mansoni glucose transport protein 0.0103 0.0183 0.0183
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.0125 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0193 0.079
Echinococcus multilocularis mothers against decapentaplegic 2 0.0033 0.0036 0.0035
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0183 0.0182
Echinococcus granulosus serotonin receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.004 0.0039
Trichomonas vaginalis hypothetical protein 0.0021 0.0011 0.0029
Echinococcus granulosus g protein coupled receptor 0.0075 0.0125 0.0125
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0104 0.0844
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.004 0.0245
Mycobacterium tuberculosis Probable dehydrogenase 0.0551 0.113 0.4272
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Brugia malayi conserved hypotetical protein 0.0028 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0067
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.009 0.0156 0.0155
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0198 0.0385 0.0385
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0021 0.0011 0.0048
Loa Loa (eye worm) hypothetical protein 0.0092 0.016 0.0573
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0015 0.0089
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0022 0.0013 0.0104
Onchocerca volvulus 0.0075 0.0125 0.0523
Entamoeba histolytica bromodomain-containing protein 0.0021 0.0011 0.0047
Schistosoma mansoni protein kinase 0.0032 0.0034 0.0034
Echinococcus granulosus histone acetyltransferase KAT2B 0.0064 0.0102 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Leishmania major glucose transporter, lmgt2 0.0032 0.0034 0.0671
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0122 0.0223 0.0223
Brugia malayi TAR-binding protein 0.003 0.003 0.0107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0108 0.0194 0.0791
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0038 0.0046 0.0045
Echinococcus granulosus neuropeptide receptor A26 0.0596 0.1223 0.1223
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0009 0.0018
Schistosoma mansoni glutamate receptor AMPA 0.1343 0.28 0.28
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0118 0.0216 0.0215
Trypanosoma cruzi heat shock protein 90, putative 0.0135 0.0251 0.5257
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0183 0.0182
Entamoeba histolytica DNA topoisomerase II, putative 0.0026 0.0022 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0116 0.0211 0.0211
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0244
Echinococcus granulosus cpg binding protein 0.0031 0.0031 0.0031
Schistosoma mansoni phosphatidylserine receptor 0.0134 0.0249 0.0249
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0018 0.0003 0.0003
Mycobacterium ulcerans beta-lactamase 0.0198 0.0385 0.5495
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0125 0.0447
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0125 0.0125
Brugia malayi Latrophilin receptor protein 2 0.0136 0.0254 0.0907
Schistosoma mansoni glutamate synthase 0.0022 0.0013 0.0013
Echinococcus granulosus thioredoxin glutathione reductase 0.0244 0.0481 0.048
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0054 0.008 0.0079
Echinococcus granulosus polybromo 1 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0079
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0132 0.0245 0.0876
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0125 0.0125
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0442 0.0899 0.0899
Trichomonas vaginalis PIKK family atypical protein kinase 0.017 0.0326 0.1343
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0059 0.009 0.0321
Mycobacterium ulcerans putative regulatory protein 0.002 0.0009 0.0107
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0296
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0022 0.0013 0.0167
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0011 0.0203
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0022 0.0013 0.0103
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0094
Toxoplasma gondii ABC1 family protein 0.0198 0.0385 0.6625
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Toxoplasma gondii DNA topoisomerase 2, putative 0.0026 0.0022 0.0367
Brugia malayi RNA recognition motif domain containing protein 0.003 0.003 0.0107
Mycobacterium tuberculosis Probable two component sensor kinase 0.0026 0.0022 0.0063
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0186
Brugia malayi Metabotropic glutamate receptor precursor. 0.0118 0.0216 0.077
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0059 0.009 0.0321
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis serotonin receptor 0.0075 0.0125 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Schistosoma mansoni microtubule-associated protein tau 0.4755 1 1
Echinococcus granulosus Niemann Pick C1 protein 0.0156 0.0296 0.0296
Toxoplasma gondii hypothetical protein 0.0019 0.0006 0.0084
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0015 0.0187
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0065 0.0065
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0125 0.0447
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0022 0.0367
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0022 0.0013 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0034 0.0034
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0021 0.0011 0.0139
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0058 0.064
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.0025 0.0088
Onchocerca volvulus 0.0345 0.0694 0.2895
Mycobacterium ulcerans hypothetical protein 0.0198 0.0385 0.5495
Loa Loa (eye worm) glutaminase 0.0341 0.0686 0.2452
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0026 0.0022 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.041
Brugia malayi Cathepsin L-like precursor 0.0018 0.0004 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.009 0.009
Giardia lamblia Heat shock protein HSP 90-alpha 0.0109 0.0196 0.1326
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0084 0.0143 0.0511
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.012 0.0219 0.2463
Schistosoma mansoni ATP-binding cassette transporter 0.1343 0.28 0.28
Schistosoma mansoni bromodomain containing protein 0.0036 0.0043 0.0043
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0125 0.0125
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0013 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0059 0.0091 0.009
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Echinococcus granulosus SAM and MBT domain containing protein 0.0116 0.0211 0.0211
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0145 0.0273 0.4705
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0118 0.0216 0.077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0125 0.0125
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0125 0.0125
Brugia malayi Inositol-1 0.0021 0.0011 0.0041
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Giardia lamblia Pms1-like protein 0.0026 0.0022 0.0139
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0125 0.0125
Mycobacterium tuberculosis Probable hydrolase 0.0198 0.0385 0.144
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0075 0.1549
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.071 0.1465 0.6104
Echinococcus multilocularis dna polymerase kappa 0.0065 0.0104 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Echinococcus multilocularis adam 0.0025 0.0019 0.0018
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0013 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.0613 0.126 0.4766
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0026 0.0022 0.0063
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0011 0.0029
Toxoplasma gondii protein kinase, putative 0.0291 0.058 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.004 0.0149
Leishmania major hypothetical protein, conserved 0.0022 0.0013 0.0244
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0084 0.0143 0.1606
Plasmodium vivax bromodomain protein, putative 0.0021 0.0011 0.0119
Trichomonas vaginalis hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) glutamate receptor 1 0.1343 0.28 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1461 0.3049 0.3049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0084 0.0143 0.2031
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.003 0.0029 0.0029
Mycobacterium ulcerans two component regulator - sensor kinase 0.0026 0.0022 0.0291
Loa Loa (eye worm) runx1 0.0031 0.0031 0.0112
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0011 0.0181
Leishmania major extracellular receptor, putative 0.0118 0.0216 0.4505
Brugia malayi Nuclear hormone receptor-like 1 0.0059 0.009 0.0321
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0033 0.0036 0.0148
Toxoplasma gondii PHD-finger domain-containing protein 0.0047 0.0066 0.1119
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0034 0.0581
Onchocerca volvulus Bile acid receptor homolog 0.0059 0.009 0.0375
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0015 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0125 0.0125
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0125 0.0447
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0038 0.0046 0.0164
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Onchocerca volvulus 0.0019 0.0006 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.009 0.0089
Schistosoma mansoni neuropeptide receptor 0.0075 0.0125 0.0125
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0031 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0011 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Echinococcus granulosus lamin 0.0061 0.0095 0.0094
Brugia malayi jmjC domain containing protein 0.0134 0.0249 0.0891
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0186
Onchocerca volvulus 0.0198 0.0385 0.1604
Leishmania major heat shock protein 83-1 0.0135 0.0251 0.5257
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.014 0.0261 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.013 0.024 0.0983
Echinococcus granulosus netrin receptor unc 5 0.0018 0.0003 0.0003
Trypanosoma brucei heat shock protein, putative 0.0135 0.0251 0.2054
Onchocerca volvulus 0.0198 0.0385 0.1604
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0094
Echinococcus multilocularis muscleblind protein 0.0227 0.0446 0.0445
Echinococcus multilocularis transcription factor eb 0.0305 0.0609 0.0609
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0065 0.0065
Echinococcus granulosus protein kinase C binding protein 1 0.0021 0.0011 0.0011
Brugia malayi Bromodomain containing protein 0.0284 0.0567 0.2024
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Loa Loa (eye worm) hypothetical protein 0.0345 0.0694 0.2478
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0038 0.0046 0.0933
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0047 0.0066 0.0531
Loa Loa (eye worm) isocitrate dehydrogenase 0.0059 0.0091 0.0324
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0086 0.1474
Schistosoma mansoni biogenic amine receptor 0.0075 0.0125 0.0125
Brugia malayi nuclear receptor NHR-88 0.0059 0.009 0.0321
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0551 0.113 0.8964
Loa Loa (eye worm) heat shock protein 90 0.0135 0.0251 0.0898
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0088
Trypanosoma cruzi ISWI complex protein 0.0112 0.0203 0.4236
Echinococcus granulosus Bromodomain containing protein 0.0021 0.0011 0.0011
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0022 0.0428
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0457 0.0932 0.0931
Trypanosoma cruzi Heat shock protein 83, putative 0.0135 0.0251 0.5257
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0125 0.0125
Entamoeba histolytica transcription factor BTF3, putative 0.0075 0.0124 0.0821
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.0062
Toxoplasma gondii PHD-finger domain-containing protein 0.0144 0.027 0.4644
Echinococcus multilocularis Niemann Pick C1 protein 0.0156 0.0296 0.0296
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0075 0.0296
Echinococcus granulosus transcription factor btf3 0.0075 0.0124 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0059 0.009 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.0385 0.8062
Loa Loa (eye worm) glutaminase 2 0.0341 0.0686 0.2452
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.003 0.0029 0.0105
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0123
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma cruzi bromodomain factor 2 protein 0.0021 0.0011 0.0201
Onchocerca volvulus Netrin receptor homolog 0.0019 0.0007 0.0029
Plasmodium vivax ataxin-2 like protein, putative 0.0072 0.0118 0.1324
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0111 0.0906
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.0025 0.0088
Plasmodium falciparum heat shock protein 90 0.0135 0.0251 0.2826
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0501 0.1025 0.1024
Leishmania major hypothetical protein, conserved 0.0072 0.0118 0.2452
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus granulosus orexin receptor type 2 0.0075 0.0125 0.0125
Mycobacterium ulcerans ferredoxin reductase 0.0022 0.0013 0.0167
Plasmodium vivax heat shock protein 86, putative 0.0135 0.0251 0.2826
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0026 0.0022 0.0123
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0026 0.0022 0.0291
Schistosoma mansoni adenoreceptor 0.0075 0.0125 0.0125
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0026 0.0022 0.0567
Brugia malayi Calcitonin receptor-like protein seb-1 0.0431 0.0876 0.3127
Brugia malayi ADAM-TS Spacer 1 family protein 0.0086 0.0149 0.0532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0159 0.0301 0.1241
Schistosoma mansoni jumonji/arid domain-containing protein 0.0518 0.1059 0.1059
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0125 0.023 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0215 0.0882
Toxoplasma gondii thioredoxin reductase 0.0242 0.0477 0.8214
Brugia malayi G-protein coupled receptor 0.0075 0.0125 0.0447
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0006 0.0005
Schistosoma mansoni inositol monophosphatase 0.0021 0.0011 0.0011
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.0025 0.0025
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0022 0.0013 0.003
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0281 0.056 0.1998
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0025 0.0018 0.035
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.004 0.0052 0.0052
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0006 0.0006
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0299 0.0298
Onchocerca volvulus 0.0018 0.0004 0.0019
Trypanosoma cruzi trypanothione reductase, putative 0.0084 0.0143 0.2979
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0013 0.0244
Schistosoma mansoni endoplasmin 0.0135 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0075 0.0125 0.0447
Schistosoma mansoni transcription factor btf3 0.0075 0.0124 0.0124
Loa Loa (eye worm) endoplasmin 0.0135 0.0251 0.0898
Loa Loa (eye worm) cysteine protease 0.0018 0.0004 0.0016
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0022 0.0013 0.0104
Schistosoma mansoni sex comb on midleg homolog 0.0116 0.0211 0.0211
Echinococcus multilocularis lysine specific demethylase 5A 0.0503 0.1027 0.1027
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0118 0.0216 0.09
Echinococcus granulosus TGF beta signal transducer SmadC 0.0073 0.0121 0.012
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0021 0.0011 0.0086
Trichomonas vaginalis heat shock protein, putative 0.011 0.0199 0.0814
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0049 0.0049
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0065 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0118 0.0216 0.077
Brugia malayi beta-lactamase family protein 0.0198 0.0385 0.1374
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0026 0.0022 0.0123
Loa Loa (eye worm) hypothetical protein 0.0245 0.0484 0.173
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0029 0.0584
Trichomonas vaginalis lymphoid specific helicase, putative 0.0021 0.0011 0.0029
Brugia malayi nuclear receptor NHR-67 0.0028 0.0025 0.0088
Echinococcus multilocularis calpain family protein 1, d 0.0028 0.0027 0.0026
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0004 0.0057
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0084 0.0143 0.2979
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0125 0.0125
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0038 0.0046 0.0164
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0026 0.0022 0.0291
Echinococcus multilocularis JmjC domain containing protein 4 0.0134 0.0249 0.0249
Loa Loa (eye worm) RGC/RGC protein kinase 0.0118 0.0216 0.077

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 0.97 uM Inhibition of [3H]glycine uptake at GlyT1 ChEMBL. 16762550
EC50 (binding) = 0.97 uM Inhibition of [3H]glycine uptake at GlyT1 ChEMBL. 16762550

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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