Detailed information for compound 509244

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.47 | Formula: C22H19N3O2S
  • H donors: 3 H acceptors: 2 LogP: 3.98 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)[C@@H]1CC(=NN1C(=S)Nc1ccccc1)c1ccc(cc1)O
  • InChi: 1S/C22H19N3O2S/c26-18-10-6-15(7-11-18)20-14-21(16-8-12-19(27)13-9-16)25(24-20)22(28)23-17-4-2-1-3-5-17/h1-13,21,26-27H,14H2,(H,23,28)/t21-/m0/s1
  • InChiKey: LGXVPDXUHWGOGM-NRFANRHFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Yersinia pestis AMP-binding enzyme family protein Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase Get druggable targets OG5_146698 All targets in OG5_146698
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Get druggable targets OG5_146698 All targets in OG5_146698
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 514 aa 23.5 %
Loa Loa (eye worm) AMP-binding enzyme family protein AMP-binding enzyme family protein   525 aa 527 aa 18.4 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) AMP-binding enzyme family protein   525 aa 456 aa 23.5 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase AMP-binding enzyme family protein   525 aa 466 aa 21.5 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 510 aa 30.0 %
Onchocerca volvulus Matrilysin homolog AMP-binding enzyme family protein   525 aa 524 aa 23.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 538 aa 27.1 %
Leishmania major 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 534 aa 25.7 %
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 544 aa 26.3 %
Plasmodium vivax long-chain fatty acid CoA ligase, putative AMP-binding enzyme family protein   525 aa 432 aa 21.8 %
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) AMP-binding enzyme family protein   525 aa 507 aa 27.2 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 440 aa 21.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative AMP-binding enzyme family protein   525 aa 454 aa 21.1 %
Leishmania mexicana 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 541 aa 23.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative AMP-binding enzyme family protein   525 aa 441 aa 19.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative AMP-binding enzyme family protein   525 aa 506 aa 21.3 %
Mycobacterium ulcerans acetyl-CoA synthetase AMP-binding enzyme family protein   525 aa 563 aa 26.3 %
Neospora caninum hypothetical protein AMP-binding enzyme family protein   525 aa 550 aa 24.0 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 531 aa 21.8 %
Leishmania infantum 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 538 aa 25.5 %
Leishmania braziliensis 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 469 aa 25.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative AMP-binding enzyme family protein   525 aa 461 aa 23.0 %
Mycobacterium ulcerans long-chain-acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 472 aa 22.0 %
Onchocerca volvulus AMP-binding enzyme family protein   525 aa 537 aa 23.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 AMP-binding enzyme family protein   525 aa 457 aa 24.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 434 aa 20.7 %
Leishmania infantum 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 538 aa 25.5 %
Trypanosoma brucei gambiense long-chain-fatty-acid-CoA ligase, putative AMP-binding enzyme family protein   525 aa 433 aa 23.1 %
Trichomonas vaginalis AMP dependent ligase, putative AMP-binding enzyme family protein   525 aa 447 aa 20.1 %
Leishmania infantum 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 471 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein AMP-binding enzyme family protein   525 aa 525 aa 22.9 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein AMP-binding enzyme family protein   525 aa 532 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD4 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 504 aa 25.0 %
Leishmania mexicana 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 541 aa 23.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) AMP-binding enzyme family protein   525 aa 502 aa 26.3 %
Mycobacterium tuberculosis Fatty-acid-CoA ligase FadD19 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 526 aa 25.7 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative AMP-binding enzyme family protein   525 aa 483 aa 18.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative AMP-binding enzyme family protein   525 aa 469 aa 22.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 469 aa 21.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative AMP-binding enzyme family protein   525 aa 495 aa 21.0 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 533 aa 24.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) AMP-binding enzyme family protein   525 aa 526 aa 21.1 %
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative AMP-binding enzyme family protein   525 aa 433 aa 23.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 AMP-binding enzyme family protein   525 aa 499 aa 23.0 %
Leishmania infantum fatty acyl CoA syntetase 1, putative AMP-binding enzyme family protein   525 aa 517 aa 24.0 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 497 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative AMP-binding enzyme family protein   525 aa 465 aa 23.0 %
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative AMP-binding enzyme family protein   525 aa 487 aa 23.6 %
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 526 aa 22.8 %
Babesia bovis acetyl-CoA synthetase, putative AMP-binding enzyme family protein   525 aa 549 aa 21.7 %
Trichomonas vaginalis antibiotic synthetase, putative AMP-binding enzyme family protein   525 aa 538 aa 21.9 %
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase AMP-binding enzyme family protein   525 aa 512 aa 22.7 %
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative AMP-binding enzyme family protein   525 aa 553 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase AMP-binding enzyme family protein   525 aa 532 aa 22.9 %
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative AMP-binding enzyme family protein   525 aa 460 aa 23.9 %
Leishmania donovani 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 538 aa 25.7 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) AMP-binding enzyme family protein   525 aa 529 aa 25.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 503 aa 22.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 490 aa 20.6 %
Onchocerca volvulus AMP-binding enzyme family protein   525 aa 537 aa 22.7 %
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) AMP-binding enzyme family protein   525 aa 501 aa 23.2 %
Plasmodium vivax acyl-CoA synthetase, putative AMP-binding enzyme family protein   525 aa 624 aa 21.5 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 559 aa 24.0 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) AMP-binding enzyme family protein   525 aa 532 aa 22.2 %
Trichomonas vaginalis AMP dependent ligase, putative AMP-binding enzyme family protein   525 aa 522 aa 22.2 %
Leishmania mexicana 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 469 aa 24.9 %
Mycobacterium ulcerans phenyloxazoline synthase MbtB AMP-binding enzyme family protein   525 aa 503 aa 25.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 481 aa 20.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase AMP-binding enzyme family protein   525 aa 532 aa 22.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase AMP-binding enzyme family protein   525 aa 563 aa 23.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) AMP-binding enzyme family protein   525 aa 494 aa 23.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 467 aa 21.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 523 aa 22.4 %
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) AMP-binding enzyme family protein   525 aa 517 aa 26.7 %
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) AMP-binding enzyme family protein   525 aa 519 aa 25.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) AMP-binding enzyme family protein   525 aa 441 aa 20.4 %
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) AMP-binding enzyme family protein   525 aa 510 aa 26.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase AMP-binding enzyme family protein   525 aa 563 aa 23.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 493 aa 22.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 496 aa 29.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 505 aa 24.9 %
Echinococcus multilocularis AMP dependent ligase AMP-binding enzyme family protein   525 aa 538 aa 22.7 %
Leishmania major fatty acyl CoA syntetase 1, putative AMP-binding enzyme family protein   525 aa 488 aa 23.8 %
Mycobacterium tuberculosis Possible long-chain-fatty-acid--CoA ligase FadD12 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 493 aa 28.0 %
Dictyostelium discoideum acetyl-CoA ligase AMP-binding enzyme family protein   525 aa 530 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative AMP-binding enzyme family protein   525 aa 474 aa 21.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE AMP-binding enzyme family protein   525 aa 523 aa 25.6 %
Drosophila melanogaster CG11407 gene product from transcript CG11407-RA AMP-binding enzyme family protein   525 aa 480 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative AMP-binding enzyme family protein   525 aa 506 aa 21.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) AMP-binding enzyme family protein   525 aa 489 aa 22.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative AMP-binding enzyme family protein   525 aa 462 aa 18.2 %
Cryptosporidium parvum acetyl-coenzyme A synthetase AMP-binding enzyme family protein   525 aa 533 aa 22.1 %
Dictyostelium discoideum hypothetical protein AMP-binding enzyme family protein   525 aa 485 aa 23.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) AMP-binding enzyme family protein   525 aa 570 aa 23.2 %
Mycobacterium tuberculosis Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (a AMP-binding enzyme family protein   525 aa 567 aa 26.5 %
Plasmodium yoelii peroxisomal-coenzyme a synthetase AMP-binding enzyme family protein   525 aa 529 aa 20.2 %
Theileria parva acetyl-coenzyme A synthetase, putative AMP-binding enzyme family protein   525 aa 530 aa 21.9 %
Loa Loa (eye worm) oxidoreductase AMP-binding enzyme family protein   525 aa 530 aa 22.8 %
Plasmodium berghei acyl-CoA synthetase, putative AMP-binding enzyme family protein   525 aa 527 aa 20.5 %
Leishmania major 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 529 aa 25.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 AMP-binding enzyme family protein   525 aa 530 aa 23.4 %
Leishmania donovani 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 471 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 AMP-binding enzyme family protein   525 aa 446 aa 24.0 %
Mycobacterium tuberculosis Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 451 aa 23.5 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase AMP-binding enzyme family protein   525 aa 539 aa 25.2 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 AMP-binding enzyme family protein   525 aa 484 aa 26.2 %
Onchocerca volvulus Flt3-interacting zinc finger protein 1 homolog AMP-binding enzyme family protein   525 aa 508 aa 21.7 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF AMP-binding enzyme family protein   525 aa 504 aa 23.8 %
Dictyostelium discoideum 4-coumarate-CoA ligase AMP-binding enzyme family protein   525 aa 541 aa 23.1 %
Leishmania infantum 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 538 aa 25.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative AMP-binding enzyme family protein   525 aa 466 aa 20.4 %
Leishmania major long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative AMP-binding enzyme family protein   525 aa 486 aa 22.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 468 aa 25.2 %
Brugia malayi AMP-binding enzyme family protein AMP-binding enzyme family protein   525 aa 479 aa 20.0 %
Dictyostelium discoideum 4-coumarate-CoA ligase AMP-binding enzyme family protein   525 aa 539 aa 23.6 %
Brugia malayi AMP-binding enzyme family protein AMP-binding enzyme family protein   525 aa 517 aa 20.7 %
Mycobacterium ulcerans fatty-acid-CoA ligase AMP-binding enzyme family protein   525 aa 461 aa 23.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 558 aa 22.8 %
Leishmania donovani fatty acyl CoA syntetase 1, putative AMP-binding enzyme family protein   525 aa 522 aa 23.8 %
Leishmania infantum long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative AMP-binding enzyme family protein   525 aa 486 aa 22.4 %
Loa Loa (eye worm) hypothetical protein AMP-binding enzyme family protein   525 aa 523 aa 22.6 %
Leishmania mexicana long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative AMP-binding enzyme family protein   525 aa 486 aa 22.2 %
Onchocerca volvulus AMP-binding enzyme family protein   525 aa 553 aa 25.0 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative AMP-binding enzyme family protein   525 aa 486 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 493 aa 25.4 %
Mycobacterium ulcerans acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 523 aa 26.6 %
Leishmania major 4-coumarate:coa ligase-like protein AMP-binding enzyme family protein   525 aa 471 aa 23.8 %
Leishmania donovani long-chain-fatty-acid-CoA ligase, putative AMP-binding enzyme family protein   525 aa 486 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase AMP-binding enzyme family protein   525 aa 508 aa 26.4 %
Giardia lamblia Long chain fatty acid CoA ligase 4 AMP-binding enzyme family protein   525 aa 424 aa 22.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 544 aa 21.9 %
Dictyostelium discoideum 4-coumarate-CoA ligase AMP-binding enzyme family protein   525 aa 539 aa 23.0 %
Brugia malayi AMP-binding enzyme family protein AMP-binding enzyme family protein   525 aa 529 aa 24.6 %
Plasmodium falciparum acyl-CoA synthetase AMP-binding enzyme family protein   525 aa 626 aa 17.6 %
Trichomonas vaginalis antibiotic synthetase, putative AMP-binding enzyme family protein   525 aa 559 aa 22.5 %
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) AMP-binding enzyme family protein   525 aa 545 aa 25.3 %
Dictyostelium discoideum hypothetical protein AMP-binding enzyme family protein   525 aa 543 aa 20.1 %
Onchocerca volvulus AMP-binding enzyme family protein   525 aa 524 aa 18.9 %
Toxoplasma gondii propionate-CoA ligase AMP-binding enzyme family protein   525 aa 568 aa 23.8 %
Plasmodium knowlesi acyl-CoA synthetase, putative AMP-binding enzyme family protein   525 aa 528 aa 21.8 %
Leishmania braziliensis fatty acyl CoA syntetase 1, putative AMP-binding enzyme family protein   525 aa 469 aa 24.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 AMP-binding enzyme family protein   525 aa 486 aa 23.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) AMP-binding enzyme family protein   525 aa 549 aa 23.0 %
Neospora caninum acetyl-coenzyme a synthetase, putative AMP-binding enzyme family protein   525 aa 509 aa 24.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0045
Onchocerca volvulus 0.0018 0.0018 0.0084
Echinococcus multilocularis tubulin epsilon chain 0.095 0.2806 0.2805
Loa Loa (eye worm) tubulin alpha-2 chain 0.127 0.3761 0.7607
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0162
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0077 0.0122
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0087 0.0224 0.0454
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0636 0.1866 0.3775
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0206 0.0205
Onchocerca volvulus 0.0087 0.0224 0.105
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0115 0.0309 0.0307
Brugia malayi MH1 domain containing protein 0.0042 0.0088 0.0179
Loa Loa (eye worm) DR-78 0.0052 0.0119 0.024
Leishmania major protein kinase, putative 0.0054 0.0124 0.0228
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0018 0.0036
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0044 0.0096 0.0095
Leishmania major protein kinase, putative 0.0054 0.0124 0.0228
Plasmodium vivax tubulin alpha chain, putative 0.127 0.3761 0.7606
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0115 0.0309 0.0624
Brugia malayi GoLoco motif family protein 0.0013 0.0002 0.0003
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Echinococcus granulosus jun protein 0.0255 0.0727 0.1144
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0055 0.0086
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.004 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0029 0.0038
Schistosoma mansoni smad1 5 8 and 0.0042 0.0088 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0131 0.0265
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0016
Brugia malayi jmjC domain containing protein 0.006 0.0145 0.0292
Onchocerca volvulus 0.0012 0.0001 0.0003
Brugia malayi Cytochrome P450 family protein 0.0067 0.0165 0.0333
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0115 0.0309 0.0486
Schistosoma mansoni nuclear receptor nhr-48 0.0052 0.0119 0.0187
Brugia malayi hypothetical protein 0.0052 0.0119 0.024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.2136 0.6353 0.6352
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0018 0.0016
Brugia malayi conserved hypotetical protein 0.0052 0.0119 0.024
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0206 0.0325
Echinococcus granulosus Tubulin alpha 1 chain 0.127 0.3761 0.592
Echinococcus multilocularis tubulin alpha chain 0.127 0.3761 0.376
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0303 0.0613
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0145 0.0227
Schistosoma mansoni jumonji domain containing protein 0.006 0.0145 0.0227
Trypanosoma cruzi epsilon tubulin, putative 0.095 0.2806 0.5667
Entamoeba histolytica serine/threonine protein kinase, putative 0.0112 0.0298 0.0603
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0276 0.0557
Echinococcus granulosus tubulin beta 1 chain 0.1665 0.4944 0.7783
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0026 0.0021
Schistosoma mansoni jun-related protein 0.0207 0.0584 0.0919
Echinococcus multilocularis tumor protein p63 0.1049 0.3101 0.31
Echinococcus multilocularis cysteine protease 0.0018 0.0018 0.0016
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0044 0.0096 0.017
Echinococcus multilocularis cpg binding protein 0.0092 0.0239 0.0238
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.001 0.0015
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0167 0.0337
Brugia malayi sodium-independent organic anion transporter family protein 0.0087 0.0224 0.0452
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0029 0.0059
Mycobacterium ulcerans endonuclease IV 0.0079 0.0201 0.0912
Trypanosoma brucei polo-like protein kinase 0.0112 0.0298 0.058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0243 0.0492
Echinococcus multilocularis Niemann Pick C1 protein 0.0203 0.0571 0.0569
Onchocerca volvulus 0.0093 0.0242 0.1135
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0186 0.0376
Giardia lamblia Kinase, PLK 0.0112 0.0298 0.0561
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0303 0.0613
Brugia malayi follicle stimulating hormone receptor 0.0247 0.0703 0.1422
Schistosoma mansoni hypothetical protein 0.0184 0.0513 0.0808
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0011 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0115 0.0309 0.0624
Onchocerca volvulus Protein patched homolog 0.0012 0.0001 0.0003
Echinococcus granulosus CREB binding protein 0.0061 0.0147 0.0231
Trichomonas vaginalis helicase, putative 0.002 0.0023 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0303 0.0613
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Echinococcus granulosus ecdysone induced protein 78C 0.0115 0.0309 0.0486
Brugia malayi tubulin alpha-2 chain 0.127 0.3761 0.7607
Schistosoma mansoni rab6-interacting 0.0141 0.0385 0.0606
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0093 0.0243 0.0492
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.001 0.0015
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.006 0.0121
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0152 0.0305
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0058
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0214 0.0433
Schistosoma mansoni cpg binding protein 0.0092 0.0239 0.0377
Echinococcus granulosus tubulin alpha 0.0923 0.2723 0.4287
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0044 0.0096 0.0095
Brugia malayi hypothetical protein 0.0087 0.0224 0.0452
Loa Loa (eye worm) fibroinase 0.0018 0.0018 0.0036
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0026 0.0123
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0093 0.0243 0.0469
Leishmania major beta tubulin 0.1665 0.4944 1
Leishmania major trypanothione reductase 0.0098 0.0257 0.0496
Schistosoma mansoni multidrug resistance protein 0.0022 0.0029 0.0046
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0074 0.0186 0.0353
Toxoplasma gondii histone lysine methyltransferase SET1 0.017 0.0473 0.0955
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.012 0.019
Brugia malayi Patched protein homolog 1 0.0012 0.0001 0.0002
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0012 0.0011
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0018 0.0016
Plasmodium vivax tubulin gamma chain, putative 0.0951 0.2807 0.5677
Onchocerca volvulus 0.0012 0.0001 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.061 0.179 0.362
Loa Loa (eye worm) hypothetical protein 0.0104 0.0276 0.0558
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0303 0.0613
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0098 0.0198
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0029 0.0038
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0152 0.015
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0012 0.0019
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0098 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0115 0.0309 0.0624
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0088 0.0179
Trypanosoma brucei protein kinase, putative 0.0105 0.0279 0.0542
Brugia malayi MAP kinase sur-1 0.0105 0.0279 0.0565
Echinococcus multilocularis Ankyrin 0.0015 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0034
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0029 0.0058
Schistosoma mansoni Smad4 0.0019 0.002 0.0031
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.012 0.0244
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0119 0.0558
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0056 0.0111
Onchocerca volvulus 0.0059 0.0141 0.0663
Echinococcus multilocularis peroxisome assembly protein 26 0.127 0.3761 0.376
Echinococcus granulosus sterol regulatory element binding protein 0.0087 0.0224 0.0353
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0032 0.0041
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0018 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.0276 0.0557
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0214 0.0433
Loa Loa (eye worm) hypothetical protein 0.0045 0.0099 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Echinococcus granulosus follistatin 0.0059 0.0141 0.0222
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0038 0.0078
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0167 0.0313
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0052 0.0119 0.024
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0095 0.0149
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0029 0.0038
Trichomonas vaginalis guanylate cyclase, putative 0.0052 0.012 0.0244
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0088 0.0087
Entamoeba histolytica hypothetical protein 0.0044 0.0095 0.0191
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0115 0.0309 0.0307
Schistosoma mansoni loxhd1 0.0141 0.0385 0.0606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0201 0.0406
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0248 0.0706 0.3487
Echinococcus granulosus tubulin delta chain 0.0415 0.1206 0.1898
Brugia malayi Tubulin beta chain 0.0415 0.1206 0.2439
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Trypanosoma brucei beta tubulin 0.0923 0.2723 0.5497
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Schistosoma mansoni tubulin subunit beta 0.0415 0.1206 0.1898
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0095 0.0149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0115 0.0309 0.0486
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.0298 0.0586
Echinococcus granulosus lipoxygenase domain containing protein 0.0141 0.0385 0.0606
Schistosoma mansoni nuclear hormone receptor 0.0115 0.0309 0.0486
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0052 0.012 0.0244
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Schistosoma mansoni CREB-binding protein 2 0.0099 0.026 0.0409
Echinococcus granulosus tumor protein p63 0.1049 0.3101 0.4882
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Schistosoma mansoni multidrug resistance protein 0.0022 0.0029 0.0046
Brugia malayi Death domain containing protein 0.0015 0.0008 0.0016
Echinococcus multilocularis hypothetical protein 0.127 0.3761 0.376
Giardia lamblia Alpha-tubulin 0.127 0.3761 0.7596
Brugia malayi 6-phosphofructokinase 0.0114 0.0304 0.0614
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0159 0.0251
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0077 0.0157
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0045
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0029 0.0059
Trichomonas vaginalis tubulin epsilon chain, putative 0.127 0.3761 0.7607
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0032 0.0064
Brugia malayi hypothetical protein 0.0052 0.0119 0.024
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0303 0.2345
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0052 0.0061
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0167 0.032
Schistosoma mansoni multidrug resistance protein 0.0022 0.0029 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0061 0.006
Echinococcus granulosus agrin 0.0059 0.0141 0.0222
Onchocerca volvulus 0.0018 0.0018 0.0084
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.012 0.0226
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0184 0.0513 0.0808
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Schistosoma mansoni alpha tubulin 0.127 0.3761 0.592
Echinococcus granulosus tubulin subunit beta 0.1665 0.4944 0.7783
Giardia lamblia GTOR 0.0093 0.0243 0.0449
Trichomonas vaginalis tubulin beta chain, putative 0.0507 0.1481 0.2996
Echinococcus granulosus peroxisome assembly protein 26 0.127 0.3761 0.592
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0018 0.0084
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.012 0.022
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0029 0.0035
Brugia malayi hypothetical protein 0.02 0.0563 0.1139
Brugia malayi hypothetical protein 0.0141 0.0385 0.0779
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.012 0.0244
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0029 0.0046
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0115 0.0309 0.0486
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Brugia malayi SRC-1 0.0044 0.0096 0.0194
Schistosoma mansoni DNA helicase recq5 0.0029 0.0052 0.0082
Schistosoma mansoni single-minded 0.0201 0.0566 0.0891
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0226 0.0356
Schistosoma mansoni microtubule-associated protein tau 0.2136 0.6353 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.002
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0099 0.0155
Schistosoma mansoni survival motor neuron protein 0.005 0.0112 0.0176
Trypanosoma cruzi zeta tubulin, putative 0.0704 0.207 0.4176
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.006 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Onchocerca volvulus 0.0012 0.0001 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0119 0.0117
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0029 0.0045
Schistosoma mansoni hypothetical protein 0.0084 0.0215 0.0338
Echinococcus granulosus cathepsin l1 0.0018 0.0018 0.0028
Trichomonas vaginalis tubulin alpha chain, putative 0.0507 0.1481 0.2996
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0017 0.0016
Brugia malayi cytochrome P450 0.0022 0.0029 0.006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0115 0.0309 0.0624
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0017 0.0016
Brugia malayi Tubulin alpha chain 0.0415 0.1206 0.2439
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Leishmania major cytochrome p450-like protein 0.0067 0.0165 0.0309
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0014 0.0005 0.0008
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0029 0.0046
Echinococcus granulosus intermediate filament protein 0.0084 0.0214 0.0337
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0056 0.0111
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0061 0.0106
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) alpha-tubulin 0.127 0.3761 0.7607
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0105 0.0279 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Brugia malayi prostaglandin transporter 0.0087 0.0224 0.0452
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0065 0.0131
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0029 0.0028
Brugia malayi MH1 domain containing protein 0.0023 0.0033 0.0066
Brugia malayi Tubulin beta-1 chain 0.1665 0.4944 1
Leishmania major cathepsin L-like protease 0.0018 0.0018 0.0012
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0675 0.1983 1
Brugia malayi PXA domain containing protein 0.0044 0.0095 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0131 0.0265
Brugia malayi hypothetical protein 0.0044 0.0095 0.0191
Plasmodium vivax SET domain protein, putative 0.0093 0.0242 0.0487
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0115 0.0309 0.0624
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0141 0.0286
Toxoplasma gondii tubulin, putative 0.0028 0.0046 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Echinococcus multilocularis tubulin subunit beta 0.1665 0.4944 0.4944
Entamoeba histolytica hypothetical protein 0.0184 0.0513 0.1039
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0029 0.0059
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0044 0.0096 0.0151
Loa Loa (eye worm) tubulin beta chain 0.0415 0.1206 0.2439
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0152 0.0239
Onchocerca volvulus 0.0154 0.0423 0.1988
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0257 0.0502
Treponema pallidum cell division protein FtsZ 0.0415 0.1206 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0029 0.0038
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0091 0.0184
Mycobacterium leprae cell division protein FtsZ 0.0415 0.1206 1
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0052 0.012 0.0244
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Brugia malayi tubulin alpha chain - mouse 0.127 0.3761 0.7607
Trypanosoma cruzi target of rapamycin kinase 3 0.0074 0.0186 0.036
Echinococcus granulosus Tubulin beta 2C chain 0.1665 0.4944 0.7783
Echinococcus multilocularis Tubulin beta 2C chain 0.1665 0.4944 0.4944
Loa Loa (eye worm) tubulin beta-4 chain 0.1665 0.4944 1
Loa Loa (eye worm) TK protein kinase 0.0035 0.007 0.0142
Echinococcus multilocularis tubulin alpha 1C chain 0.127 0.3761 0.376
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Brugia malayi hypothetical protein 0.0675 0.1984 0.4012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Echinococcus granulosus tyrosine protein kinase Src64B 0.0044 0.0096 0.0151
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Echinococcus granulosus tubulin alpha chain 0.127 0.3761 0.592
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Schistosoma mansoni retinoic acid receptor RXR 0.0115 0.0309 0.0486
Trypanosoma brucei zeta tubulin 0.0704 0.207 0.4173
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Leishmania major cathepsin L-like protease 0.0069 0.0169 0.0318
Schistosoma mansoni tubulin subunit alpha 0.0415 0.1206 0.1898
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Brugia malayi orphan nuclear receptor NR2E1 0.0052 0.0119 0.024
Plasmodium vivax tubulin alpha chain, putative 0.127 0.3761 0.7606
Leishmania major beta tubulin 0.1665 0.4944 1
Brugia malayi Myosin head containing protein 0.0012 0.0001 0.0002
Plasmodium vivax tubulin beta chain, putative 0.1665 0.4944 1
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0303 0.0613
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0012 0.0019
Brugia malayi Uncoordinated protein 44 0.0015 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0082 0.021 0.0424
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0054 0.0124 0.0234
Loa Loa (eye worm) hypothetical protein 0.0203 0.0571 0.1154
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0675 0.1983 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0056 0.0112
Trypanosoma cruzi tubulin delta chain 0.0588 0.1723 0.3473
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.0527 0.0829
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0095 0.0149
Schistosoma mansoni organic anion transporter 0.0087 0.0224 0.0352
Echinococcus multilocularis Tubulin alpha 1 chain 0.127 0.3761 0.376
Trypanosoma brucei beta tubulin 0.1665 0.4944 1
Brugia malayi Steroid receptor seven-up type 2 0.0115 0.0309 0.0624
Echinococcus granulosus lamin dm0 0.0084 0.0214 0.0337
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0167 0.0313
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0045
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0065 0.0108
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0018 0.0017 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0061 0.006
Loa Loa (eye worm) tubulin beta-1 chain 0.1665 0.4944 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0058 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Onchocerca volvulus 0.0018 0.0018 0.0084
Echinococcus multilocularis tubulin beta 1 chain 0.1665 0.4944 0.4944
Mycobacterium ulcerans putative regulatory protein 0.0149 0.041 0.1976
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.0816 0.1613
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0029 0.0038
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0087 0.0224 0.0352
Brugia malayi Pre-SET motif family protein 0.0093 0.0242 0.0489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0115 0.0309 0.0624
Echinococcus multilocularis cysteine protease 0.0018 0.0018 0.0016
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0012 0.0019
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0087 0.0224 0.0222
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.0257 0.0519
Schistosoma mansoni RAR-like nuclear receptor 0.0115 0.0309 0.0486
Onchocerca volvulus 0.0087 0.0224 0.105
Brugia malayi beta-tubulin, identical 0.1665 0.4944 1
Onchocerca volvulus Bile acid receptor homolog 0.0115 0.0309 0.145
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.0257 0.1196
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0099 0.0155
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0108
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0029 0.0038
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0099 0.0155
Echinococcus multilocularis neuropeptide s receptor 0.0957 0.2825 0.2824
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0415 0.1206 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0279 0.044
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0042
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0083 0.0131
Echinococcus granulosus Polycystic kidney disease protein 0.0141 0.0385 0.0606
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0052 0.012 0.0119
Onchocerca volvulus 0.0012 0.0001 0.0003
Echinococcus multilocularis CREB binding protein 0.0016 0.0012 0.0011
Echinococcus granulosus tubulin gamma 1 chain 0.0951 0.2807 0.4419
Loa Loa (eye worm) doublecortin family protein 0.0141 0.0385 0.0779
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0095 0.0093
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0052 0.0119 0.0187
Trypanosoma brucei tubulin delta chain 0.0588 0.1723 0.3469
Echinococcus granulosus CREB binding protein 0.0016 0.0012 0.002
Trichomonas vaginalis abcb9, putative 0.0022 0.0029 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0029 0.0038
Brugia malayi Thioredoxin reductase 0.0098 0.0257 0.0519
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0052 0.0104
Echinococcus multilocularis tubulin alpha 3 chain 0.127 0.3761 0.376
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0029 0.0035
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0061 0.0122
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Echinococcus granulosus tubulin alpha chain 0.127 0.3761 0.592
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0026 0.0053
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0095 0.0149
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0303 0.0301
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0119 0.0117
Onchocerca volvulus 0.0018 0.0018 0.0084
Onchocerca volvulus Protein patched homolog 0.0012 0.0001 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0303 0.0613
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.012 0.0226
Entamoeba histolytica hypothetical protein 0.0023 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0024
Leishmania major delta tubulin, putative 0.0588 0.1723 0.3469
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0279 0.0565
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0159 0.0251
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Leishmania major beta tubulin 0.1665 0.4944 1
Brugia malayi Patched related family protein 12 0.0012 0.0001 0.0002
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0095 0.0149
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0029 0.0046
Echinococcus multilocularis expressed protein 0.0759 0.2233 0.2232
Echinococcus granulosus tubulin alpha 1C chain 0.127 0.3761 0.592
Leishmania major beta tubulin 0.1665 0.4944 1
Brugia malayi SPARC precursor 0.0059 0.0141 0.0286
Loa Loa (eye worm) hypothetical protein 0.0243 0.069 0.1395
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0065 0.2103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0061 0.01
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.069 0.1086
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0119 0.0187
Plasmodium falciparum tubulin delta chain, putative 0.0415 0.1206 0.2438
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0029 0.0038
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0044 0.0096 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.002 0.004
Plasmodium vivax vivapain-2 0.0018 0.0018 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0115 0.0309 0.145
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0029 0.0059
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0029 0.0058
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0059
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0303 0.2456
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0026 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0415 0.1206 0.2439
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0093 0.0243 0.0469
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0276 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Toxoplasma gondii protease inhibitor PI2 0.0059 0.0141 0.0284
Echinococcus multilocularis tubulin alpha chain 0.127 0.3761 0.376
Trichomonas vaginalis tubulin, putative 0.0443 0.129 0.2608
Loa Loa (eye worm) steroid hormone receptor 0.0115 0.0309 0.0624
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0141 0.0286
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0588 0.1723 0.3484
Trichomonas vaginalis abcb9, putative 0.0022 0.0029 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0115 0.0309 0.0624
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0013
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0095 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Schistosoma mansoni Smad4 0.0019 0.002 0.0031
Trypanosoma cruzi beta tubulin, putative 0.1665 0.4944 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Brugia malayi 6-phosphofructokinase 0.0113 0.0303 0.0613
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Brugia malayi protein C24B5.3 0.0012 0.0001 0.0002
Brugia malayi MH2 domain containing protein 0.0042 0.0088 0.0179
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0018 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Echinococcus multilocularis Tubulin alpha 1 chain 0.127 0.3761 0.376
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0029 0.0058
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0099 0.0199
Brugia malayi nuclear hormone receptor 0.0052 0.0119 0.024
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0052 0.0119 0.0187
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0141 0.0284
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0058 0.0092
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0303 0.0613
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0095 0.0191
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0056 0.0111
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0303 0.059
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0029 0.0038
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0507 0.1481 0.2996
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Giardia lamblia Beta tubulin 0.1665 0.4944 1
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0119 0.024
Onchocerca volvulus 0.0087 0.0225 0.1055
Schistosoma mansoni smad 0.0019 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0035
Brugia malayi jmjC domain containing protein 0.0065 0.0159 0.0322
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0115 0.0309 0.0307
Brugia malayi ecdysone receptor 0.0052 0.0119 0.024
Onchocerca volvulus Putative organic anion transporter 0.0087 0.0224 0.105
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0115 0.0309 0.0624
Schistosoma mansoni agrin 0.0059 0.0141 0.0222
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0032 0.0064
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0165 0.0315
Echinococcus multilocularis Tubulin beta 2C chain 0.1665 0.4944 0.4944
Toxoplasma gondii beta tubulin 0.1665 0.4944 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0141 0.0286
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0023 0.0047
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0077 0.0157
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0095 0.0149
Echinococcus granulosus serine protein kinase ATM 0.0018 0.0017 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0279 0.0565
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0024
Onchocerca volvulus 0.0507 0.1481 0.6959
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Brugia malayi Tubulin alpha-2 chain 0.127 0.3761 0.7607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Brugia malayi steroid hormone receptor 0.0115 0.0309 0.0624
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Schistosoma mansoni z-protein (S1r protein) 0.0044 0.0095 0.0149
Brugia malayi PAS domain containing protein 0.0201 0.0566 0.1145
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0279 0.0565
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0014 0.0007 0.0013
Echinococcus multilocularis tubulin alpha 0.0923 0.2723 0.2722
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Echinococcus granulosus Tubulin beta 2C chain 0.1665 0.4944 0.7783
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0223 0.0631 0.513
Echinococcus multilocularis RUN 0.0141 0.0385 0.0384
Schistosoma mansoni tubulin subunit alpha 0.127 0.3761 0.592
Echinococcus multilocularis Tubulin beta 2C chain 0.1665 0.4944 0.4944
Schistosoma mansoni thyroid hormone receptor 0.0115 0.0309 0.0486
Schistosoma mansoni thyroid hormone receptor 0.0115 0.0309 0.0486
Schistosoma mansoni hypothetical protein 0.0865 0.2552 0.4017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0042
Brugia malayi MH1 domain containing protein 0.0042 0.0088 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0052 0.0119 0.024
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0029 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0095 0.0191
Trichomonas vaginalis tubulin alpha chain, putative 0.0923 0.2723 0.5508
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0018 0.0028
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.0276 0.0557
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0029 0.0028
Echinococcus multilocularis smad 0.0042 0.0088 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0008 0.0013
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0044 0.0096 0.0151
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0029 0.0038
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0096 0.0151
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Echinococcus granulosus Smad4 0.0042 0.0088 0.0139
Brugia malayi Cytochrome P450 family protein 0.0022 0.0029 0.006
Echinococcus granulosus CREB binding protein 0.0016 0.0012 0.002
Schistosoma mansoni follistatin 0.0059 0.0141 0.0222
Echinococcus granulosus tubulin alpha 3 chain 0.127 0.3761 0.592
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0064 0.0154 0.0242
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0046 0.0072
Loa Loa (eye worm) hypothetical protein 0.0064 0.0154 0.0311
Plasmodium falciparum alpha tubulin 1 0.127 0.3761 0.7606
Leishmania major beta tubulin 0.1665 0.4944 1
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0065 0.0114
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.002 0.004
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0029 0.0059
Giardia lamblia Gamma tubulin 0.0951 0.2807 0.5658
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0085 0.0133
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.038 0.3001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0077 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Toxoplasma gondii FATC domain-containing protein 0.0018 0.0017 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0119 0.0187
Brugia malayi MH2 domain containing protein 0.0019 0.002 0.004
Schistosoma mansoni hypothetical protein 0.0013 0.0002 0.0002
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.019 0.0299
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0065 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0115 0.0309 0.0624
Brugia malayi nuclear hormone receptor 0.0115 0.0309 0.0624
Brugia malayi bZIP transcription factor family protein 0.0255 0.0727 0.147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) CBP-B 0.0069 0.017 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0115 0.0309 0.0624
Echinococcus granulosus lipoxygenase domain containing protein 0.0141 0.0385 0.0606
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0115 0.0309 0.0486
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0102 0.0161
Loa Loa (eye worm) hypothetical protein 0.0854 0.2519 0.5094
Brugia malayi Cytochrome P450 family protein 0.0067 0.0165 0.0333
Plasmodium vivax glutathione reductase, putative 0.0098 0.0257 0.0517
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0029 0.0059
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Echinococcus granulosus thyroid hormone receptor alpha 0.0052 0.0119 0.0187
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0065 0.0114
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0058 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0029 0.0038
Onchocerca volvulus 0.0141 0.0385 0.181
Trypanosoma cruzi MFS transporter, putative 0.0087 0.0224 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0202 0.0409
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0167 0.0262
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0029 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0099 0.0155
Loa Loa (eye worm) agrin synaptic family protein 0.0059 0.0141 0.0286
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0115 0.0309 0.0624
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0017 0.0015
Trichomonas vaginalis guanylate cyclase, putative 0.0052 0.012 0.0244
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0029 0.0028
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Plasmodium vivax JmjC domain containing protein 0.0016 0.0012 0.0023
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1665 0.4944 0.4944
Schistosoma mansoni cpg binding protein 0.0092 0.0239 0.0377
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0131 0.0265
Leishmania major cathepsin L-like protease 0.0018 0.0018 0.0012
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0058 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0201 0.148
Loa Loa (eye worm) TK protein kinase 0.004 0.0083 0.0168
Loa Loa (eye worm) tubulin gamma chain 0.0951 0.2807 0.5678
Onchocerca volvulus 0.0022 0.0029 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0129 0.0261
Brugia malayi nuclear hormone receptor family member nhr-6 0.0052 0.0119 0.024
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Echinococcus granulosus nuclear receptor nhr 48 0.0052 0.0119 0.0187
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0012 0.0023
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0303 0.1432
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.038 0.1827
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0029 0.0038
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0029 0.0059
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0077 0.0076
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0029 0.0038
Brugia malayi FAT domain containing protein 0.0014 0.0005 0.001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0115 0.0309 0.0486
Loa Loa (eye worm) hypothetical protein 0.127 0.3761 0.7607
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0112 0.0298 0.0297
Brugia malayi ABC transporter family protein 0.0022 0.0029 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0018 0.0036
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0017 0.0026
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0079 0.0125
Echinococcus granulosus Solute carrier organic anion transporter family 0.0087 0.0224 0.0352
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0012 0.0011
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0088 0.0139
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0029 0.0038
Echinococcus granulosus tyrosine protein kinase Lyn 0.0045 0.01 0.0157
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0115 0.0309 0.0486
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0119 0.0558
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0058 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0008 0.0016
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0854 0.2519 0.5094
Leishmania major cathepsin L-like protease 0.0018 0.0018 0.0012
Loa Loa (eye worm) pax transcription factor protein 2 0.0247 0.0703 0.1421
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis tubulin gamma chain, putative 0.1665 0.4944 1
Trypanosoma brucei alpha tubulin 0.127 0.3761 0.7601
Entamoeba histolytica hypothetical protein 0.0044 0.0095 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0151 0.0306
Leishmania major zeta tubulin, putative 0.0704 0.207 0.4173
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0065 0.0132
Brugia malayi Doublecortin family protein 0.0141 0.0385 0.0779
Trichomonas vaginalis taga, putative 0.0022 0.0029 0.0059
Brugia malayi nuclear receptor NHR-67 0.0052 0.0119 0.024
Loa Loa (eye worm) transcription factor SMAD2 0.061 0.179 0.362
Brugia malayi Tubulin alpha-2 chain 0.127 0.3761 0.7607
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0032 0.0085
Trichomonas vaginalis tubulin alpha chain, putative 0.0507 0.1481 0.2996
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.0276 0.0535
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0095 0.0149
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0095 0.0093
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0081 0.0128
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0081 0.0206 0.0417
Echinococcus multilocularis tubulin gamma 1 chain 0.0951 0.2807 0.2806
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0095 0.0149
Toxoplasma gondii beta-1 tubulin, putative 0.1665 0.4944 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.012 0.0244
Loa Loa (eye worm) hypothetical protein 0.0248 0.0706 0.1428
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0303 0.1432
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0096 0.0095
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0133
Echinococcus granulosus geminin 0.0865 0.2552 0.4017
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0081 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Brugia malayi CHE-14 protein 0.0087 0.0224 0.0454
Giardia lamblia Beta tubulin 0.1665 0.4944 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0095 0.0149
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0167 0.0165
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0045
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0095 0.0093
Loa Loa (eye worm) RecQ helicase 0.0042 0.0091 0.0184
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0083 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Echinococcus multilocularis dnaJ subfamily B 0.0843 0.2484 0.2483
Mycobacterium ulcerans cell division protein FtsZ 0.0415 0.1206 0.6038
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0095 0.0149
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0065 0.0221
Schistosoma mansoni aryl hydrocarbon receptor 0.0201 0.0566 0.0891
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0096 0.0095
Echinococcus granulosus death domain containing protein 0.0015 0.0008 0.0013
Brugia malayi serine/threonine-protein kinase plk-2 0.0112 0.0298 0.0603
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0029 0.0046
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0056 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0046
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.0816 0.6744
Plasmodium falciparum tubulin epsilon chain, putative 0.095 0.2806 0.5674
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0117
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0167 0.0337
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0061 0.0122
Schistosoma mansoni hypothetical protein 0.0865 0.2552 0.4017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0115 0.0309 0.0624
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0056 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Schistosoma mansoni smad 0.0042 0.0088 0.0139
Loa Loa (eye worm) Smad1 0.0042 0.0088 0.0179
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0095 0.0149
Schistosoma mansoni organic anion transporter 0.0087 0.0224 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0108
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0024
Onchocerca volvulus Putative organic anion transporter 0.0087 0.0224 0.105
Schistosoma mansoni tubulin subunit gamma 0.0951 0.2807 0.4419
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0095 0.0149
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0152 0.0661
Giardia lamblia Kinase, CMGC MAPK 0.0105 0.0279 0.0523
Leishmania major beta tubulin 0.1665 0.4944 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.001
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis tubulin alpha chain, putative 0.0507 0.1481 0.2996
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Brugia malayi MH2 domain containing protein 0.061 0.179 0.362
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0099 0.026 0.0409
Onchocerca volvulus 0.0012 0.0001 0.0003
Trichomonas vaginalis tubulin epsilon chain, putative 0.1665 0.4944 1
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0029 0.0046
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0029 0.0038
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0093 0.0243 0.0469
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0077 0.0122
Onchocerca volvulus Huntingtin homolog 0.0372 0.1077 0.506
Schistosoma mansoni Smad4 0.0042 0.0088 0.0139
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0032 0.0041
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Brugia malayi hypothetical protein 0.0012 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0029 0.0038
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0095 0.0093
Echinococcus granulosus neuropeptide receptor A26 0.0957 0.2825 0.4446
Schistosoma mansoni lamin 0.0084 0.0214 0.0337
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0093 0.0243 0.0469
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0039 0.0037
Brugia malayi secreted modular calcium-binding protein 1 0.0059 0.0141 0.0286
Trypanosoma brucei alpha tubulin 0.127 0.3761 0.7601
Plasmodium vivax tubulin epsilon chain, putative 0.095 0.2806 0.5674
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0115 0.0309 0.0486
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0095 0.0191
Schistosoma mansoni hypothetical protein 0.0843 0.2484 0.391
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0052 0.0082
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0255 0.0727 0.0726
Echinococcus multilocularis lamin dm0 0.0084 0.0214 0.0213
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0029 0.0038
Toxoplasma gondii alpha tubulin TUBA1 0.127 0.3761 0.7606
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0088 0.0139
Echinococcus multilocularis ecdysone induced protein 78C 0.0115 0.0309 0.0307
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0099 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0012 0.0023
Brugia malayi hypothetical protein 0.0184 0.0513 0.1039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0242 0.038
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0093 0.0243 0.0475
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0024
Trypanosoma brucei alpha tubulin 0.127 0.3761 0.7601
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0077 0.0133
Schistosoma mansoni hypothetical protein 0.0084 0.0215 0.0338
Onchocerca volvulus 0.0012 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0064 0.0154 0.0311
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0279 0.0565
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0065 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0117
Loa Loa (eye worm) histone methyltransferase 0.003 0.0055 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0224 0.0454
Loa Loa (eye worm) hypothetical protein 0.0064 0.0154 0.0311
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0029 0.0027
Trichomonas vaginalis tubulin epsilon chain, putative 0.127 0.3761 0.7607
Echinococcus granulosus Ankyrin 0.0015 0.0008 0.0013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0105 0.0279 0.0542
Entamoeba histolytica protein kinase rad3, putative 0.0018 0.0017 0.0034
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0029 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0186 0.0376
Schistosoma mansoni lipoxygenase 0.0586 0.1717 0.2702
Schistosoma mansoni hypothetical protein 0.0264 0.0753 0.1185
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0029 0.0038
Mycobacterium tuberculosis Probable reductase 0.0223 0.0631 0.3108
Onchocerca volvulus 0.0087 0.0224 0.105
Echinococcus multilocularis beta tubulin 0.1665 0.4944 0.4944
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0061 0.01
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.012 0.0119
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0029 0.006
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0762 0.2243 0.4537
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0029 0.0046
Loa Loa (eye worm) tubulin beta chain 0.1665 0.4944 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0279 0.0548
Echinococcus multilocularis tubulin alpha chain 0.127 0.3761 0.376
Brugia malayi Patched related family protein 10 0.0012 0.0001 0.0002
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0032 0.0051
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0052 0.0104
Loa Loa (eye worm) hypothetical protein 0.0046 0.0103 0.0208
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Echinococcus granulosus dnaJ subfamily B 0.0843 0.2484 0.391
Leishmania major gamma-tubulin 0.0951 0.2807 0.5667
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Trichomonas vaginalis tubulin epsilon chain, putative 0.1665 0.4944 1
Echinococcus granulosus Tubulin beta 2C chain 0.1665 0.4944 0.7783
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0052 0.0104
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0077 0.0122
Trypanosoma brucei alpha tubulin 0.127 0.3761 0.7601
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Schistosoma mansoni steroid hormone receptor ad4bp 0.0115 0.0309 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Leishmania major beta tubulin 0.1665 0.4944 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0039 0.0061
Echinococcus granulosus mitogen activated protein kinase 0.0105 0.0279 0.044
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Brugia malayi hypothetical protein 0.0012 0.0001 0.0002
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0095 0.0191
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Loa Loa (eye worm) cytochrome P450 0.0022 0.0029 0.006
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0029 0.0038
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0225 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Trypanosoma brucei trypanothione reductase 0.0098 0.0257 0.0496
Onchocerca volvulus Huntingtin homolog 0.0372 0.1077 0.506
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0029 0.0038
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0036
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0007 0.0014
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0061 0.0096
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Echinococcus multilocularis multidrug resistance protein 1 0.0015 0.001 0.0008
Schistosoma mansoni cellular tumor antigen P53 0.0154 0.0423 0.0666
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0141 0.0286
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0054 0.0124 0.0234
Onchocerca volvulus 0.0084 0.0214 0.1006
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0012 0.0019
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.008 0.0138
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.007 0.011
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0093 0.0243 0.0383
Treponema pallidum NADH oxidase 0.0034 0.0065 0.0472
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0029 0.0038
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0056 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0034
Leishmania major beta tubulin 0.1665 0.4944 1
Echinococcus granulosus Tubulin beta 2C chain 0.1665 0.4944 0.7783
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0077 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0115 0.0309 0.0624
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0032 0.0195
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0024
Mycobacterium leprae putative cytochrome p450 0.0022 0.0029 0.0027
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0029 0.0028
Onchocerca volvulus Serine\/threonine kinase homolog 0.0112 0.0298 0.1401
Trichomonas vaginalis tubulin epsilon chain, putative 0.0415 0.1206 0.2439
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0008 0.0016
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0064 0.0154 0.0152
Loa Loa (eye worm) hypothetical protein 0.0154 0.0423 0.0856
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0115 0.0309 0.0307
Onchocerca volvulus 0.0052 0.0119 0.0558
Echinococcus multilocularis CREB binding protein 0.0016 0.0012 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0029 0.0046
Schistosoma mansoni alpha tubulin 0.127 0.3761 0.592
Leishmania major cathepsin L-like protease 0.0069 0.0169 0.0318
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0095 0.0149
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0115 0.0309 0.0624
Loa Loa (eye worm) hypothetical protein 0.0093 0.0242 0.0489
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0184 0.0513 0.0512
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0061 0.006
Echinococcus granulosus Niemann Pick C1 protein 0.029 0.0831 0.1308
Trichomonas vaginalis tubulin, putative 0.0507 0.1481 0.2996
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0141 0.0286
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0029 0.0038
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0029 0.0059
Brugia malayi GoLoco motif family protein 0.0013 0.0002 0.0003
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0058 0.0091
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0002
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Plasmodium vivax multidomain scavenger receptor, putative 0.0141 0.0385 0.0778
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0029 0.0038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0242 0.024
Brugia malayi sodium-independent organic anion transporter family protein 0.0087 0.0224 0.0452
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0032 0.0051
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0248 0.0706 0.5761
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0029 0.0038
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0095 0.0093
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.002 0.0018
Toxoplasma gondii cathepsin CPL 0.0018 0.0018 0.0034
Onchocerca volvulus 0.0115 0.0309 0.145
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0139
Entamoeba histolytica recQ family helicase, putative 0.0032 0.006 0.0121
Brugia malayi intermediate filament protein 0.0084 0.0214 0.0433
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0018
Trichomonas vaginalis tubulin gamma chain, putative 0.095 0.2806 0.5675
Loa Loa (eye worm) nuclear factor I 0.0023 0.0033 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0141 0.0286
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0029 0.0038
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0052 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis tubulin alpha chain 0.127 0.3761 0.376
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.002
Schistosoma mansoni tyrosine kinase 0.0044 0.0096 0.0151
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.0703 0.1422
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0056 0.153
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0206 0.0325
Schistosoma mansoni cpg binding protein 0.0087 0.0225 0.0354
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0065 0.0132
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0029 0.0038
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0058 0.0099
Echinococcus granulosus tyrosine kinase 0.004 0.0083 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0077 0.0113
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.0257 0.0517
Brugia malayi protein-tyrosine kinase 0.004 0.0083 0.0168
Brugia malayi hypothetical protein 0.0064 0.0154 0.0311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Plasmodium vivax delta tubulin, putative 0.0415 0.1206 0.2438
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0242 0.024
Schistosoma mansoni hypothetical protein 0.0207 0.0584 0.0919
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0018 0.0036
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0029 0.0059
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0029 0.0038
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0043
Brugia malayi hypothetical protein 0.0067 0.0165 0.0334
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0079 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0117
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0141 0.0284
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0029 0.0058
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Brugia malayi hypothetical protein 0.0087 0.0224 0.0452
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0242 0.0487
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0018 0.0036
Echinococcus multilocularis expressed conserved protein 0.0191 0.0534 0.0532
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0203 0.0571 0.1154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0115 0.0309 0.0486
Onchocerca volvulus 0.0087 0.0224 0.105
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0065 0.0114
Schistosoma mansoni coup transcription factor 0.0115 0.0309 0.0486
Entamoeba histolytica hypothetical protein 0.0184 0.0513 0.1039
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0303 0.0613
Echinococcus granulosus beta tubulin 0.1665 0.4944 0.7783
Echinococcus multilocularis tubulin delta chain 0.0415 0.1206 0.1205
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0145 0.0143
Brugia malayi MH2 domain containing protein 0.0042 0.0088 0.0179
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0012 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0095 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0115 0.0309 0.0624
Giardia lamblia Epsilon tubulin 0.0443 0.1288 0.2573
Loa Loa (eye worm) hypothetical protein 0.0059 0.0141 0.0286
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0093 0.0243 0.0475
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0139
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Schistosoma mansoni hypothetical protein 0.0084 0.0215 0.0338
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0169 0.0325
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0061 0.006
Schistosoma mansoni tubulin subunit alpha 0.127 0.3761 0.592
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0096 0.0151
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0008 0.0013
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0065 0.0131
Trypanosoma brucei alpha tubulin, putative 0.0507 0.1481 0.2979
Echinococcus multilocularis geminin 0.0865 0.2552 0.2551
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0141 0.0284
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis CREB binding protein 0.0068 0.0167 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0115 0.0309 0.0486
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0064 0.0154 0.0242
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0029 0.0059
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.019 0.0189
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0061 0.02
Echinococcus granulosus phd:f box containing protein 0.0016 0.0012 0.0019
Brugia malayi hypothetical protein 0.0012 0.0001 0.0002
Schistosoma mansoni DNA helicase recq1 0.0029 0.0052 0.0082
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Leishmania major hypothetical protein, conserved 0.0104 0.0276 0.0535
Trypanosoma brucei epsilon tubulin 0.095 0.2806 0.5664
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0154 0.0311
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0012 0.0019
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0223 0.0631 0.3108
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0065 0.0365
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0061 0.0122
Trypanosoma cruzi tubulin gamma chain 0.0951 0.2807 0.567
Brugia malayi Pre-SET motif family protein 0.0636 0.1866 0.3775
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0043
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Brugia malayi hypothetical protein 0.0243 0.069 0.1395
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0027
Onchocerca volvulus Protein ultraspiracle homolog 0.0115 0.0309 0.145
Trichomonas vaginalis set domain proteins, putative 0.0724 0.2128 0.4305
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0032 0.005
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0095 0.0149
Leishmania major beta tubulin 0.1665 0.4944 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0223 0.0631 0.3108
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0052 0.012 0.019
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0454
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0165 0.0333
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0114
Trichomonas vaginalis tubulin gamma chain, putative 0.0415 0.1206 0.2439
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.0104 0.0102
Leishmania major beta tubulin 0.1665 0.4944 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) beta-tubulin 0.1665 0.4944 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0186 0.0376
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0029 0.0059
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0242 0.038
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0088 0.0179
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0018 0.0036
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0024
Onchocerca volvulus 0.0149 0.041 0.1924
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0093 0.0243 0.0242
Loa Loa (eye worm) GoLoco domain-containing protein family protein 0.0013 0.0002 0.0003
Toxoplasma gondii thioredoxin reductase 0.0098 0.0257 0.0517
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0012 0.0023
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.0276 0.0557
Echinococcus multilocularis Polycystic kidney disease protein 0.0141 0.0385 0.0384
Trichomonas vaginalis tubulin beta chain, putative 0.127 0.3761 0.7607
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0027 0.0042
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.038 0.1827
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0167 0.0262
Echinococcus granulosus microtubule associated protein 2 0.2136 0.6353 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0105 0.0279 0.0548
Schistosoma mansoni patched 1 0.0087 0.0224 0.0353
Echinococcus granulosus bloom syndrome protein 0.0042 0.0091 0.0143
Brugia malayi protein C24B5.3 0.0012 0.0001 0.0002
Brugia malayi Tubulin gamma chain 0.0951 0.2807 0.5678
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0032 0.0167
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Toxoplasma gondii endonuclease IV APN 0.0079 0.0201 0.0405
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0115 0.0309 0.0486
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0586 0.1717 0.2702
Loa Loa (eye worm) glutathione reductase 0.0098 0.0257 0.0519
Echinococcus multilocularis tubulin alpha 1C chain 0.127 0.3761 0.376
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0009 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0024
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0018 0.0084
Brugia malayi isocitrate dehydrogenase 0.0033 0.0061 0.0124
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.0298 0.0586
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0012 0.0019
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0206 0.0417
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0023 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.012 0.0244
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0077 0.0157
Onchocerca volvulus 0.02 0.0563 0.2645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0186 0.0376
Leishmania major beta tubulin 0.1665 0.4944 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0243 0.0492
Echinococcus granulosus tubulin alpha chain 0.127 0.3761 0.592
Onchocerca volvulus 0.0081 0.0206 0.097
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0023 0.0047
Brugia malayi nuclear hormone receptor family member odr-7 0.0052 0.0119 0.024
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0018 0.0017 0.0026
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0044 0.0095 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Echinococcus granulosus expressed conserved protein 0.0191 0.0534 0.084
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0077 0.0157
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0112 0.0298 0.058
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0099 0.0097
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0119 0.0187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0029 0.0038
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0061 0.0124
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0119 0.024
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0125 0.0236
Echinococcus granulosus tubulin alpha chain 0.127 0.3761 0.592
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0303 0.0613
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.002 0.004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.0279 0.0548
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0066
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0083 0.0082
Entamoeba histolytica hypothetical protein 0.0044 0.0095 0.0191
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.0257 0.0404
Onchocerca volvulus 0.0724 0.2129 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Schistosoma mansoni kinase 0.0057 0.0135 0.0213
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Echinococcus granulosus tubulin epsilon chain 0.095 0.2806 0.4417
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0029 0.0038
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Echinococcus multilocularis sterol regulatory element binding protein 0.0087 0.0224 0.0223
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0165 0.0315
Brugia malayi Tubulin alpha chain 0.127 0.3761 0.7607
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0065 0.0221
Schistosoma mansoni hypothetical protein 0.0022 0.0029 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0017
Giardia lamblia Delta tubulin 0.0415 0.1206 0.2405
Leishmania major cytochrome p450-like protein 0.0022 0.0029 0.0035
Trichomonas vaginalis abcb9, putative 0.0022 0.0029 0.0059
Schistosoma mansoni smdr2 0.0022 0.0029 0.0046
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0093 0.0243 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0047
Trypanosoma brucei zeta tubulin, putative 0.0704 0.207 0.4173
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0201 0.0405
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0009 0.0016
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0095 0.0191
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0044 0.0096 0.0095
Chlamydia trachomatis endonuclease IV 0.0079 0.0201 1
Schistosoma mansoni rab6-interacting 0.0141 0.0385 0.0606
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0157
Brugia malayi Raf kinase 0.0046 0.0102 0.0207
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0087 0.0224 0.0451
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0077 0.0122
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0105 0.0279 0.0548
Trypanosoma brucei beta tubulin 0.1665 0.4944 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0623 0.1827 0.3696
Echinococcus multilocularis agrin 0.0059 0.0141 0.014
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.127 0.3761 0.7607
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0105
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0032 0.0064
Loa Loa (eye worm) alpha-tubulin 0.127 0.3761 0.7607
Loa Loa (eye worm) BEN-1 protein 0.1665 0.4944 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0141 0.0385 0.0384
Echinococcus granulosus Tubulin alpha 1 chain 0.127 0.3761 0.592
Brugia malayi nuclear receptor RXR 0.0052 0.0119 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Schistosoma mansoni intermediate filament proteins 0.0084 0.0214 0.0337
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0087 0.0224 0.0452
Echinococcus granulosus Niemann Pick C1 protein 0.0203 0.0571 0.0898
Trypanosoma brucei epsilon tubulin 0.095 0.2806 0.5664
Trypanosoma brucei tubulin gamma chain 0.0951 0.2807 0.5667
Trichomonas vaginalis tubulin gamma chain, putative 0.0951 0.2807 0.5678
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0167 0.032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0052 0.0105
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Brugia malayi Niemann-Pick C1 protein precursor 0.0203 0.0571 0.1154
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0018 0.0028
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Mycobacterium tuberculosis Probable oxidoreductase 0.0248 0.0706 0.3487
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.0102 0.0161
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0152 0.0661
Brugia malayi TAZ zinc finger family protein 0.0099 0.026 0.0526
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.0104 0.0164
Loa Loa (eye worm) CYP4Cod1 0.0067 0.0165 0.0333
Echinococcus granulosus cpg binding protein 0.0092 0.0239 0.0377
Echinococcus multilocularis FTZ F1 alpha 0.0115 0.0309 0.0307
Loa Loa (eye worm) hypothetical protein 0.0141 0.0385 0.0779
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0007
Entamoeba histolytica tubulin family protein 0.1665 0.4944 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0052 0.0082
Schistosoma mansoni tyrosine kinase 0.0044 0.0096 0.0151
Loa Loa (eye worm) nuclear hormone receptor 0.0052 0.0119 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Trichomonas vaginalis tubulin, putative 0.0507 0.1481 0.2996
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0115 0.0309 0.0624
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0091 0.0184
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0131 0.0265
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0017 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0046
Trypanosoma cruzi tubulin delta chain 0.0588 0.1723 0.3473
Schistosoma mansoni hypothetical protein 0.0141 0.0385 0.0606
Mycobacterium tuberculosis Cell division protein FtsZ 0.0415 0.1206 0.6038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0115 0.0309 0.0624
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Schistosoma mansoni lamin 0.0084 0.0214 0.0337
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0223 0.0631 0.3108
Trypanosoma brucei beta tubulin 0.1665 0.4944 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0206 0.058 0.0913
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0159 0.0322
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0029 0.0059
Echinococcus multilocularis Tubulin alpha 1 chain 0.127 0.3761 0.376
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0018 0.0084
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0098 0.0154
Echinococcus multilocularis Niemann Pick C1 protein 0.029 0.0831 0.0829
Leishmania major beta tubulin 0.1665 0.4944 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0052 0.0119 0.0187
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0151 0.0289
Entamoeba histolytica tubulin gamma chain 0.0951 0.2807 0.5678
Loa Loa (eye worm) tubulin alpha-3 chain 0.0762 0.2243 0.4537
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.006 0.0104
Loa Loa (eye worm) hypothetical protein 0.0372 0.1077 0.2178
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0096 0.0151
Schistosoma mansoni alpha tubulin 0.127 0.3761 0.592
Schistosoma mansoni zinc finger protein 0.0052 0.0119 0.0187
Schistosoma mansoni tubulin subunit alpha 0.127 0.3761 0.592
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0065 0.0088
Brugia malayi regulator of G-protein signaling egl-10 0.0044 0.0095 0.0191
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0112 0.0298 0.0469
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0058 0.0056
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0443 0.1288 0.2605
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0056 0.039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0186 0.0376
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0035
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0169 0.0325
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0152 0.0661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0017 0.0034
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.004 0.0085 0.0171
Schistosoma mansoni transcription factor LCR-F1 0.0184 0.0513 0.0808
Brugia malayi PXA domain containing protein 0.0044 0.0095 0.0191
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0242 0.038
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0415 0.1206 0.2439
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0108
Loa Loa (eye worm) tubulin alpha 2 0.0854 0.2519 0.5094
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0074 0.0186 0.0353
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0039 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0023 0.0047
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0052 0.0105
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0058 0.0117
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.001 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0221
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0115 0.0309 0.0307
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0008 0.0013
Leishmania major beta tubulin 0.1665 0.4944 1
Leishmania major epsilon tubulin, putative 0.095 0.2806 0.5664
Echinococcus granulosus alpha tubulin 0.127 0.3761 0.592
Echinococcus multilocularis serine protein kinase ATM 0.0018 0.0017 0.0015
Onchocerca volvulus 0.0084 0.0214 0.1006
Schistosoma mansoni tubulin subunit beta 0.1665 0.4944 0.7783
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0018 0.0028
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0415 0.1206 0.2439
Plasmodium falciparum thioredoxin reductase 0.0034 0.0065 0.0131
Trypanosoma brucei beta tubulin 0.1665 0.4944 1
Echinococcus multilocularis protein dispatched 1 0.0099 0.0261 0.026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0242 0.038
Toxoplasma gondii target of rapamycin (TOR), putative 0.0069 0.0172 0.0346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Schistosoma mansoni nuclear receptor 0.0052 0.0119 0.0187
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0055 0.0053
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0115 0.0309 0.0486
Brugia malayi multidrug resistance protein 3 0.0022 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0084 0.0215 0.0338
Onchocerca volvulus 0.0247 0.0703 0.3301
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0223 0.0631 0.3108
Schistosoma mansoni nuclear receptor 0.0052 0.0119 0.0187
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0029 0.0038
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.002 0.0031
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Loa Loa (eye worm) hypothetical protein 0.0079 0.0201 0.0406
Trypanosoma cruzi epsilon tubulin, putative 0.095 0.2806 0.5667
Loa Loa (eye worm) tubulin beta-2A chain 0.1665 0.4944 1
Brugia malayi Pax transcription factor protein 2 0.0247 0.0703 0.1421
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0152 0.0239
Loa Loa (eye worm) cysteine protease 0.0018 0.0018 0.0036
Echinococcus multilocularis neuropeptide receptor A26 0.0957 0.2825 0.2824
Leishmania major p-glycoprotein 0.0022 0.0029 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0115 0.0309 0.0624
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0065 0.0221
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0058 0.0092
Schistosoma mansoni hypothetical protein 0.005 0.0112 0.0176
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0141 0.0284
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.0102 0.0101
Echinococcus multilocularis protein patched 0.0087 0.0224 0.0223
Loa Loa (eye worm) hypothetical protein 0.0052 0.0119 0.024
Echinococcus multilocularis lamin 0.0084 0.0214 0.0213
Onchocerca volvulus 0.0052 0.0119 0.0558
Brugia malayi hypothetical protein 0.0044 0.0095 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0088 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0115 0.0309 0.0624
Toxoplasma gondii beta-tubulin, putative 0.1665 0.4944 1
Echinococcus multilocularis CREB binding protein 0.0016 0.0012 0.0011
Echinococcus granulosus Tubulin alpha 1 chain 0.127 0.3761 0.592
Entamoeba histolytica recQ family DNA helicase 0.0015 0.0009 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Loa Loa (eye worm) tubulin alpha 2 0.0854 0.2519 0.5094
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0052 0.0119 0.0117
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0169 0.0325
Brugia malayi nuclear receptor NHR-88 0.0115 0.0309 0.0624
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0103
Brugia malayi hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0095 0.0191
Brugia malayi nuclear receptor NHR-88 0.0052 0.0119 0.024
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0038 0.0075
Entamoeba histolytica tubulin alpha chain, putative 0.127 0.3761 0.7607
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0854 0.2519 0.5094
Loa Loa (eye worm) nuclear receptor NHR-67 0.0052 0.0119 0.024
Echinococcus granulosus smad 0.0042 0.0088 0.0139
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0039 0.0061
Schistosoma mansoni polycystin 1-related 0.0141 0.0385 0.0606
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0112 0.0298 0.0603
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0088 0.0139
Entamoeba histolytica hypothetical protein 0.0184 0.0513 0.1039
Loa Loa (eye worm) hypothetical protein 0.0141 0.0385 0.0779
Trypanosoma brucei epsilon tubulin 0.0923 0.2723 0.5497
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Echinococcus granulosus tubulin alpha 3 chain 0.127 0.3761 0.592
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0065 0.0131
Trypanosoma cruzi zeta tubulin, putative 0.0704 0.207 0.4176
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0095 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Plasmodium vivax vivapain-2 0.0018 0.0018 0.0034
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0052 0.012 0.5312
Trichomonas vaginalis tubulin, putative 0.1665 0.4944 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Onchocerca volvulus 0.0012 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0047 0.0104 0.0164
Leishmania major cathepsin L-like protease 0.0018 0.0018 0.0012
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0061 0.01
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0029 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0056 0.0112
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0115 0.0309 0.0624
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Entamoeba histolytica protein kinase, putative 0.0035 0.007 0.0142
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0029 0.0059
Onchocerca volvulus 0.0141 0.0385 0.181
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.012 0.0244
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0154 0.0242
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0032 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.069 0.0688
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0105 0.0279 0.0565
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0008
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0052 0.005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0027 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0039 0.0037
Onchocerca volvulus Putative organic anion transporter 0.0087 0.0224 0.105
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0085 0.0083
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0152 0.0283
Loa Loa (eye worm) hypothetical protein 0.0028 0.0048 0.0096
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0014 0.0005 0.0003
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0064 0.0154 0.0311
Plasmodium falciparum LCCL domain-containing protein 0.0141 0.0385 0.0778
Echinococcus granulosus lamin 0.0084 0.0214 0.0337
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Plasmodium falciparum tubulin beta chain 0.1665 0.4944 1
Brugia malayi hypothetical protein 0.0372 0.1077 0.2178
Brugia malayi Patched related family protein 4 0.0012 0.0001 0.0002
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0303 0.0477
Mycobacterium leprae Possible regulatory protein 0.0052 0.012 0.0798
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0255 0.0727 0.1144
Brugia malayi glutathione reductase 0.0098 0.0257 0.0519
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0084 0.0214 0.0433
Echinococcus multilocularis jun protein 0.0255 0.0727 0.0726
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0091 0.0089
Loa Loa (eye worm) hypothetical protein 0.0059 0.0141 0.0286
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0201 0.0405
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Mycobacterium ulcerans epimerase 0.0021 0.0026 0.0021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0022 0.0111
Entamoeba histolytica hypothetical protein 0.0018 0.0017 0.0034
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0038 0.0078
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0083 0.0082
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0052 0.0119 0.0117
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0029 0.0059
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0087 0.0224 0.0222
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0112 0.0227
Schistosoma mansoni tubulin subunit epsilon 0.095 0.2806 0.4417
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0303 0.0613
Loa Loa (eye worm) hypothetical protein 0.0064 0.0154 0.0311
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0214 0.0433
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0061 0.0124
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0018 0.0012
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0095 0.0093
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0012 0.0019
Schistosoma mansoni lipoxygenase 0.0332 0.0958 0.1509
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0095 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0191
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0124 0.0234
Echinococcus granulosus tubulin alpha chain 0.127 0.3761 0.592
Loa Loa (eye worm) hypothetical protein 0.0064 0.0154 0.0311
Brugia malayi MH1 domain containing protein 0.0023 0.0033 0.0066
Entamoeba histolytica hypothetical protein 0.0184 0.0513 0.1039
Brugia malayi nuclear receptor RXR 0.0064 0.0154 0.0311
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.0257 0.0255
Echinococcus granulosus FTZ F1 alpha 0.0115 0.0309 0.0486
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0298 0.0469
Brugia malayi Cytochrome P450 family protein 0.0022 0.0029 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0115 0.0309 0.0624
Echinococcus multilocularis tubulin alpha chain 0.127 0.3761 0.376
Brugia malayi Cell division protein ftsZ 0.0415 0.1206 0.2439
Brugia malayi bHLH-PAS transcription factor 0.0149 0.041 0.0828
Brugia malayi hypothetical protein 0.0141 0.0385 0.0779
Entamoeba histolytica tubulin family protein 0.1665 0.4944 1
Onchocerca volvulus 0.0018 0.0018 0.0084
Brugia malayi Smad1 0.0042 0.0088 0.0179
Echinococcus multilocularis Smad4 0.0042 0.0088 0.0087
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0029 0.0027
Loa Loa (eye worm) phosphatidylinositol 3 0.0093 0.0243 0.0492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0117
Leishmania major beta tubulin 0.1665 0.4944 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0044 0.0096 0.0095
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0029 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Echinococcus multilocularis tubulin alpha 3 chain 0.127 0.3761 0.376
Loa Loa (eye worm) raf kinase 0.0045 0.0098 0.0199
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0065 0.0108
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0083 0.0131
Loa Loa (eye worm) ctsf protein 0.0018 0.0018 0.0036
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0452
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0058 0.0117
Onchocerca volvulus 0.0087 0.0224 0.105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Brugia malayi sodium-independent organic anion transporter family protein 0.0087 0.0224 0.0452
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0056 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0029 0.0038
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.002 0.0092
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0303 0.0477
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0018 0.0017 0.0034
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0145 0.0143
Echinococcus granulosus neuropeptide s receptor 0.0957 0.2825 0.4446
Loa Loa (eye worm) hypothetical protein 0.0372 0.1077 0.2178
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0029 0.0046
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0056 0.0111
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0024
Loa Loa (eye worm) tubulin alpha 2 0.0347 0.1001 0.2025
Schistosoma mansoni smad1 5 8 and 0.0042 0.0088 0.0139
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0093 0.0243 0.0383
Giardia lamblia Alpha-tubulin 0.127 0.3761 0.7596
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0061 0.006
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0154 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0115 0.0232
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0124 0.0234
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0061 0.0106
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0115 0.0309 0.0307
Echinococcus multilocularis expressed protein 0.0059 0.0141 0.014
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0029 0.0038
Plasmodium falciparum glutathione reductase 0.0034 0.0065 0.0131
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0923 0.2723 0.5508
Loa Loa (eye worm) tubulin alpha chain 0.127 0.3761 0.7607
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0065 0.0132
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0029 0.0058
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0303 0.0477
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0053
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0018 0.0034
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.007 0.0068
Brugia malayi Cathepsin L-like precursor 0.0018 0.0018 0.0036
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0099 0.0199
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0029 0.0059
Onchocerca volvulus 0.0052 0.012 0.0566
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0018 0.0016
Schistosoma mansoni netrin receptor unc5 0.0015 0.0008 0.0013
Brugia malayi ecdysteroid receptor 0.0115 0.0309 0.0624
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0018 0.0028
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0115 0.0309 0.0486
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.0276 0.0541
Echinococcus granulosus CREB binding protein 0.0099 0.026 0.0409
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0065 0.0131
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0018 0.0034
Onchocerca volvulus 0.0018 0.0018 0.0084
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0115 0.0309 0.0486
Echinococcus granulosus G protein signaling modulator 2 0.0013 0.0002 0.0002
Echinococcus granulosus tubulin alpha 1C chain 0.127 0.3761 0.592
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0242 0.038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0816 0.1651
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0012 0.0011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0029 0.0059
Plasmodium falciparum alpha tubulin 2 0.127 0.3761 0.7606
Echinococcus granulosus single minded 2 0.0149 0.041 0.0645
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0586 0.1717 0.1715
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0035
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0065 0.0108
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0012 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0052 0.0105
Brugia malayi hypothetical protein 0.0064 0.0154 0.0311
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0191
Echinococcus granulosus beta tubulin 0.1665 0.4944 0.7783
Plasmodium falciparum thioredoxin reductase 0.0098 0.0257 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0029 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0054 0.0108
Leishmania major cathepsin L-like protease 0.0069 0.0169 0.0318
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Echinococcus multilocularis Tubulin beta 2C chain 0.1665 0.4944 0.4944
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0095 0.0149
Loa Loa (eye worm) SRC-1 0.0044 0.0096 0.0194
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0032 0.0051
Plasmodium falciparum tubulin gamma chain 0.0951 0.2807 0.5677
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0096 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0172 0.0347
Schistosoma mansoni cytochrome P450 0.0022 0.0029 0.0046
Echinococcus multilocularis transfer RNA-Lys 0.0149 0.041 0.0408
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0129 0.0261
Brugia malayi CXXC zinc finger family protein 0.0087 0.0225 0.0454
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0303 0.059
Schistosoma mansoni smad1 5 8 and 0.0042 0.0088 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.004
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0029 0.0038
Echinococcus multilocularis mitogen activated protein kinase 3 0.0105 0.0279 0.0278
Echinococcus multilocularis nuclear receptor nhr 48 0.0052 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0107 0.0283 0.0572
Echinococcus granulosus tubulin subunit TubB 0.127 0.3761 0.592
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0083 0.0166
Echinococcus granulosus tubulin beta 4A class IVa 0.1665 0.4944 0.7783
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0061 0.0122
Loa Loa (eye worm) BEN-1 protein 0.1665 0.4944 1
Brugia malayi phosphofructokinase 0.0113 0.0303 0.0613
Brugia malayi Protein kinase domain containing protein 0.0016 0.0012 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0119 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0131 0.0265
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0105 0.0279 0.0542
Giardia lamblia Beta tubulin 0.1665 0.4944 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0169 0.0318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0243 0.0492
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0067 0.0165 0.0727
Echinococcus multilocularis mitogen activated protein kinase 0.0105 0.0279 0.0278
Echinococcus granulosus mitogen activated protein kinase 3 0.0105 0.0279 0.044
Echinococcus multilocularis tubulin subunit TubB 0.127 0.3761 0.376
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0027
Onchocerca volvulus 0.0018 0.0018 0.0084
Trichomonas vaginalis tubulin beta chain, putative 0.1665 0.4944 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0029 0.0038
Echinococcus granulosus Protein patched homolog 1 0.0087 0.0224 0.0353
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0065 0.0108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0159 0.0251
Echinococcus granulosus RUN 0.0141 0.0385 0.0606
Brugia malayi hypothetical protein 0.0104 0.0276 0.0558
Brugia malayi Tubulin beta chain 0.0507 0.1481 0.2996
Leishmania major beta tubulin 0.1665 0.4944 1
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.012 0.0244
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0119 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.012 0.0244
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0029 0.0059
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0065 0.0131
Brugia malayi alpha-tubulin 0.127 0.3761 0.7607
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0029 0.0028
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0248 0.0706 0.3487
Plasmodium falciparum glutathione reductase 0.0098 0.0257 0.0517
Trypanosoma brucei cytochrome P450, putative 0.0067 0.0165 0.0309
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0029 0.0042
Brugia malayi Patched family protein 0.0012 0.0001 0.0002
Echinococcus multilocularis beta tubulin 0.1665 0.4944 0.4944
Brugia malayi hypoxia-induced factor 1 0.0623 0.1827 0.3696
Leishmania major cytochrome p450-like protein 0.0022 0.0029 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0145 0.0294
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0036
Leishmania major beta tubulin 0.1665 0.4944 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0095 0.0191
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.002 0.0018
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0029 0.0038
Loa Loa (eye worm) tubulin alpha chain 0.127 0.3761 0.7607
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0165 0.0333
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0056 0.153
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Onchocerca volvulus 0.005 0.0112 0.0526
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0303 0.0596
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0061 0.0096
Mycobacterium tuberculosis Probable dehydrogenase 0.0223 0.0631 0.3108
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0093 0.0243 0.0492
Trichomonas vaginalis tubulin alpha chain, putative 0.1665 0.4944 1
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0095 0.0149
Trypanosoma cruzi alpha tubulin, putative 0.127 0.3761 0.7602
Echinococcus granulosus expressed protein 0.0759 0.2233 0.3515
Echinococcus multilocularis musashi 0.0084 0.0214 0.0213
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0762 0.2243 0.4537
Leishmania major alpha tubulin 0.127 0.3761 0.7601
Leishmania major beta tubulin 0.1665 0.4944 1
Echinococcus multilocularis 0.0022 0.0029 0.0028
Echinococcus multilocularis follistatin 0.0059 0.0141 0.014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0029 0.0059
Echinococcus granulosus Tubulin beta 2C chain 0.1665 0.4944 0.7783
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0035
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0008 0.0007
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0065 0.0108
Echinococcus multilocularis Tubulin beta 2C chain 0.1665 0.4944 0.4944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0079
Brugia malayi tailless protein 0.0052 0.0119 0.024
Trichomonas vaginalis adenylate cyclase, putative 0.0052 0.012 0.0244
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0167 0.0337
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0077 0.0157
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0115 0.0309 0.0307
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0169 0.0325
Brugia malayi photoreceptor-specific nuclear receptor 0.0115 0.0309 0.0624
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0201 0.0912
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0152 0.0661
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.0036
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.006 0.0097
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0091 0.0184
Loa Loa (eye worm) hypothetical protein 0.0675 0.1984 0.4012
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0029 0.0037
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0141 0.0385 0.0384
Entamoeba histolytica tubulin alpha-1 chain 0.127 0.3761 0.7607
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0029 0.0059
Leishmania major beta tubulin 0.1665 0.4944 1
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0152 0.0239
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0119 0.0187
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0141 0.0286
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0105 0.0279 0.0563
Loa Loa (eye worm) hypothetical protein 0.0039 0.008 0.0162
Toxoplasma gondii alpha-tubulin I, putative 0.127 0.3761 0.7606
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0008 0.0038
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0065 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0298 0.0603
Schistosoma mansoni tubulin subunit delta 0.0415 0.1206 0.1898
Loa Loa (eye worm) hypothetical protein 0.0115 0.0309 0.0624
Leishmania major cathepsin L-like protease 0.0018 0.0018 0.0012
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0002

Activities

Activity type Activity value Assay description Source Reference
CD50 (ADMET) = 248 uM Cytotoxicity against human HeLa cells after 24 hrs ChEMBL. 18394884
CD50 (ADMET) = 248 uM Cytotoxicity against human HeLa cells after 24 hrs ChEMBL. 18394884
IC50 (binding) > 12.5 uM Inhibition of Yersinia pestis YbtE assessed as incorporation of [3H]salicyl group to HMWP2 protein ChEMBL. 18394884
IC50 (binding) > 12.5 uM Inhibition of Yersinia pestis YbtE assessed as incorporation of [3H]salicyl group to HMWP2 protein ChEMBL. 18394884
IC50 (functional) > 75 uM Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron limiting PMH-D medium ChEMBL. 18394884
IC50 (functional) > 75 uM Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron rich PMH-D medium ChEMBL. 18394884
IC50 (functional) = 83 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron deficient GAST-D medium ChEMBL. 18394884
IC50 (functional) = 83 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron deficient GAST-D medium ChEMBL. 18394884
IC50 (functional) = 105 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron rich GAST-D medium ChEMBL. 18394884
IC50 (functional) = 105 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron rich GAST-D medium ChEMBL. 18394884
MIC90 (functional) > 75 uM Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron limiting PMH-D medium ChEMBL. 18394884
MIC90 (functional) > 75 uM Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron rich PMH-D medium ChEMBL. 18394884
MIC90 (functional) = 125 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron deficient GAST-D medium ChEMBL. 18394884
MIC90 (functional) = 125 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron deficient GAST-D medium ChEMBL. 18394884
MIC90 (functional) = 250 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron rich GAST-D medium ChEMBL. 18394884
MIC90 (functional) = 250 uM Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in presence of iron rich GAST-D medium ChEMBL. 18394884
Ratio (functional) = 2 Ratio of MIC90 for Mycobacterium tuberculosis H37Rv in iron rich GAST-D medium to MIC90 for Mycobacterium tuberculosis H37Rv in presence of iron limiting GAST-D medium ChEMBL. 18394884
Ratio IC50 (binding) = 1786 Ratio of IC50 for drug to 5'-O-[N-(salicyl)-sulfomyl]-adenosine for Yersinia pestis YbtE assessed as incorporation of [3H]salicyl group to HMWP2 protein ChEMBL. 18394884
Ratio IC50 (functional) = 1 Ratio of IC50 for Mycobacterium tuberculosis H37Rv in iron rich GAST-D medium to IC50 for Mycobacterium tuberculosis H37Rv in presence of iron limiting GAST-D medium ChEMBL. 18394884
Ratio IC50 (binding) = 1786 Ratio of IC50 for drug to 5'-O-[N-(salicyl)-sulfomyl]-adenosine for Yersinia pestis YbtE assessed as incorporation of [3H]salicyl group to HMWP2 protein ChEMBL. 18394884
Selectivity index (functional) < 3 Selectivity index, CD50 for human HeLa cells to IC50 for Yersinia pestis KIM6-2082.1+ in presence of iron limiting PMH-D medium ChEMBL. 18394884
Selectivity index (functional) = 3 Selectivity index, CD50 for human HeLa cells to IC50 for Mycobacterium tuberculosis H37Rv in presence of iron limiting GAST-D medium ChEMBL. 18394884

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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