Detailed information for compound 928728

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 811.921 | Formula: C40H57N7O11
  • H donors: 10 H acceptors: 11 LogP: 0.03 Rotable bonds: 30
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)NCC(=O)O)[C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)O)N)C)Cc1ccccc1)CCC(=O)O)C
  • InChi: 1S/C40H57N7O11/c1-6-22(3)33(39(57)42-21-32(51)52)47-40(58)34(23(4)7-2)46-37(55)29(17-18-31(49)50)44-38(56)30(20-25-11-9-8-10-12-25)45-35(53)24(5)43-36(54)28(41)19-26-13-15-27(48)16-14-26/h8-16,22-24,28-30,33-34,48H,6-7,17-21,41H2,1-5H3,(H,42,57)(H,43,54)(H,44,56)(H,45,53)(H,46,55)(H,47,58)(H,49,50)(H,51,52)/t22-,23-,24-,28-,29-,30-,33-,34-/m0/s1
  • InChiKey: STBPMVIZSUHXME-NTPKDUSHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus opioid receptor, delta 1 Starlite/ChEMBL References
Rattus norvegicus Delta opioid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis allatostatin A receptor Delta opioid receptor   372 aa 302 aa 28.5 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Delta opioid receptor   372 aa 320 aa 25.6 %
Brugia malayi ORL1-like opioid receptor Delta opioid receptor   372 aa 300 aa 24.7 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Delta opioid receptor   372 aa 315 aa 28.6 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Delta opioid receptor   372 aa 366 aa 22.7 %
Brugia malayi GnHR receptor homolog Delta opioid receptor   372 aa 313 aa 18.5 %
Onchocerca volvulus Delta opioid receptor   372 aa 316 aa 26.9 %
Schistosoma mansoni peptide (allatostatin)-like receptor Delta opioid receptor   372 aa 353 aa 29.2 %
Onchocerca volvulus Delta opioid receptor   372 aa 386 aa 22.8 %
Onchocerca volvulus Delta opioid receptor   372 aa 349 aa 22.1 %
Loa Loa (eye worm) neuropeptide F receptor Delta opioid receptor   372 aa 317 aa 23.3 %
Onchocerca volvulus Delta opioid receptor   372 aa 353 aa 21.0 %
Onchocerca volvulus Delta opioid receptor   372 aa 344 aa 22.1 %
Echinococcus granulosus allatostatin A receptor Delta opioid receptor   372 aa 302 aa 27.8 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Delta opioid receptor   372 aa 330 aa 24.2 %
Echinococcus granulosus thyrotropin releasing hormone receptor Delta opioid receptor   372 aa 330 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.1035 0.3083 0.7067
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0068 0.0193
Echinococcus granulosus intermediate filament protein 0.0053 0.0131 0.031
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0083 0.019
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0366
Schistosoma mansoni lamin 0.0053 0.0131 0.03
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0022 0.0036 0.0084
Onchocerca volvulus 0.0013 0.0008 0.0059
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis regulator of G protein signaling 7 0.0237 0.0682 0.0682
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0006 0.0006
Brugia malayi Uncoordinated protein 44 0.0032 0.0066 0.015
Onchocerca volvulus 0.0013 0.0008 0.0059
Schistosoma mansoni goodpasture antigen-binding protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) G-protein coupled receptor 0.0165 0.0467 0.1069
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0155 0.0355
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0022 0.0036 0.0366
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0022 0.0036 0.0257
Echinococcus granulosus metabotropic glutamate receptor 2 0.0194 0.0554 0.131
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0018 0.0051
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0014 0.0088
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0066 0.0719
Echinococcus multilocularis 0.0015 0.0014 0.0014
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis tumor protein p63 0.034 0.0993 0.0993
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0071
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0034 0.0034
Loa Loa (eye worm) plexin A 0.0077 0.0202 0.0462
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1223 0.365 0.8368
Onchocerca volvulus 0.0053 0.0131 0.0946
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0067 0.0154
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0015 0.0006
Loa Loa (eye worm) phosphofructokinase 0.0106 0.029 0.0664
Echinococcus granulosus neuropeptide FF receptor 2 0.0165 0.0467 0.1104
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0034 0.0078
Brugia malayi cytochrome P450 0.0015 0.0014 0.0032
Brugia malayi larval opioid receptor 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.005 0.0121 0.0278
Giardia lamblia O-linked GlcNAc transferase 0.004 0.009 0.0256
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0078 0.0221
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0366
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0448
Brugia malayi Bromodomain containing protein 0.0029 0.0058 0.0133
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0078 0.0078
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0131 0.0299
Brugia malayi Sema domain containing protein 0.0027 0.0052 0.0118
Schistosoma mansoni ran 0.0024 0.0042 0.0096
Loa Loa (eye worm) glycosyl transferase 0.002 0.003 0.0068
Brugia malayi ecdysteroid receptor 0.0021 0.0034 0.0077
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0068 0.0494
Schistosoma mansoni coup transcription factor 0.0021 0.0034 0.0078
Echinococcus multilocularis sterol regulatory element binding protein 0.009 0.0241 0.0241
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0 0.0001
Echinococcus granulosus orexin receptor type 2 0.0165 0.0467 0.1104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0034 0.0081
Echinococcus multilocularis Regulator of G protein signaling 20 0.0237 0.0682 0.0682
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0143 0.0402 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0214 0.0615 0.8939
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0033 0.0237
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) Plekhf2 protein 0.0022 0.0036 0.0081
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0 0.0001
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Echinococcus multilocularis tyrosine kinase 0.0025 0.0045 0.0045
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Echinococcus multilocularis Niemann Pick C1 protein 0.0209 0.06 0.06
Trypanosoma cruzi extracellular receptor, putative 0.0022 0.0036 0.0368
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0028 0.0054 0.0392
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Schistosoma mansoni neuropeptide F-like receptor 0.0165 0.0467 0.107
Echinococcus granulosus 7tm_1 domain containing protein 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0137 0.0325
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0058 0.0133
Echinococcus granulosus regulator of G protein signaling 7 0.0237 0.0682 0.1614
Brugia malayi DNA-binding protein LAG-1 0.0012 0.0006 0.0013
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus sterol regulatory element binding protein 0.009 0.0241 0.0569
Echinococcus multilocularis dynamin 1 0.0022 0.0036 0.0036
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Brugia malayi Pre-SET motif family protein 0.0412 0.1209 0.2771
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0015 0.0033
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0238 0.0687 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus peregrin 0.0029 0.0058 0.0138
Loa Loa (eye worm) UDP-Galactose:b-N-acetylglucosamine b1,4-galactosyltransferase 4 0.0048 0.0116 0.0265
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1223 0.365 0.8368
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0054 0.0578
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0014 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0448 0.6477
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0098 0.1078
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0034 0.0077
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) doublecortin family protein 0.002 0.003 0.0068
Echinococcus granulosus oxysterol binding protein 9 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0257 0.059
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0259 0.0259
Echinococcus multilocularis g-protein coupled receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Loa Loa (eye worm) uncoordinated protein 104 0.0022 0.0036 0.0081
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0015 0.0367
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.0253 0.6296
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Brugia malayi Dopamine receptor 0.0165 0.0467 0.1069
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0591 0.1354
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Onchocerca volvulus 0.0025 0.0045 0.0326
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Schistosoma mansoni adenoreceptor 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0285 0.0828 0.1897
Entamoeba histolytica G protein alpha subunit, putative 0.001 0 0.0004
Echinococcus multilocularis sex peptide receptor 0.0165 0.0467 0.0467
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0022 0.0036 0.0084
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0302 0.0878 0.2012
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0034 0.0077
Trypanosoma brucei protein kinase, putative 0.0028 0.0054 0.0578
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus exocyst complex component 2 0.0012 0.0006 0.0014
Plasmodium vivax PH domain containing protein 0.0022 0.0036 0.0884
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Brugia malayi Regulator of G protein signaling domain containing protein 0.0237 0.0682 0.1563
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0034 0.0348
Echinococcus granulosus 7TM GPCR rhodopsin 0.0165 0.0467 0.1104
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0014 0.0088
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1178 0.3514 0.3514
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0165 0.0467 0.107
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0015 0.0006
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.1178 0.3514 1
Echinococcus multilocularis oxysterol binding protein 9 0.0022 0.0036 0.0036
Schistosoma mansoni jumonji domain containing protein 0.0076 0.02 0.0458
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus tumor protein p63 0.034 0.0993 0.2349
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Echinococcus granulosus GPCR family 3 C terminal 0.0038 0.0083 0.0197
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis cytohesin 1 0.0022 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0038 0.0083 0.0191
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Treponema pallidum hypothetical protein 0.0016 0.0018 0.0000051679
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0028 0.0054 0.0578
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0122 0.1426
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0034 0.0077
Brugia malayi nuclear receptor NHR-88 0.001 0 0.0000046864
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni histamine h1 receptor 0.0165 0.0467 0.107
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0221 0.0221
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0015 0.0042
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0034 0.0078
Plasmodium falciparum glutathione reductase 0.0094 0.0253 0.6296
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0083 0.0913
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0165 0.0467 0.1069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi GnHR receptor homolog 0.0165 0.0467 0.1069
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0001 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0122 0.1598
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0014 0.0088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Echinococcus multilocularis fmrfamide receptor 0.0165 0.0467 0.0467
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0015 0.0006
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0109
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus lamin dm0 0.0053 0.0131 0.031
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0022 0.0036 0.0036
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0 0.0000046864
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0042 0.0096
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0025 0.0624
Echinococcus multilocularis GPCR, family 3, C terminal 0.0038 0.0083 0.0083
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.003 0.0744
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0013 0.0008 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0034 0.0077
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0237 0.0682 0.1564
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0014 0.0088
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0057 0.016
Brugia malayi ecdysone receptor 0.001 0 0.0000046864
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Brugia malayi neuropeptide F receptor 0.0165 0.0467 0.1069
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Echinococcus granulosus nuclear receptor nhr 48 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0034 0.0077
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0399 0.4532
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.2059 0.2059
Echinococcus granulosus G protein coupled receptor 139 0.0165 0.0467 0.1104
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.1008 0.2311
Schistosoma mansoni ap endonuclease 0.0038 0.0083 0.0191
Loa Loa (eye worm) syntrophin-1 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0096 0.0257 0.059
Onchocerca volvulus 0.0165 0.0467 0.3379
Schistosoma mansoni nuclear hormone receptor 0.001 0 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0059 0.0149 0.034
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0019 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.031 0.071
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Loa Loa (eye worm) sema domain-containing protein 0.0027 0.0052 0.0118
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0356
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0067 0.0732
Onchocerca volvulus 0.0027 0.0052 0.0374
Echinococcus multilocularis Oxysterol binding protein 11 0.0022 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Brugia malayi Dopamine receptor protein 1 0.0165 0.0467 0.1069
Echinococcus granulosus beta 14 N acetylgalactosaminyltransferase 0.0048 0.0116 0.0274
Brugia malayi Nuclear hormone receptor E75 0.001 0 0.0000046864
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0066 0.0156
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0068 0.0494
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0006 0.0013
Schistosoma mansoni zinc finger protein 0.0022 0.0036 0.0081
Schistosoma mansoni hypothetical protein 0.0029 0.0058 0.0134
Onchocerca volvulus Poor gastrulation protein homolog 0.0038 0.0083 0.0601
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Onchocerca volvulus 0.0022 0.0036 0.0255
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.004 0.009 0.0255
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Brugia malayi Receptor family ligand binding region containing protein 0.0025 0.0045 0.0103
Echinococcus multilocularis semaphorin 5B 0.0027 0.0052 0.0052
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0142 0.0403
Echinococcus granulosus dynamin 1 0.0022 0.0036 0.0084
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.003
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0057 0.5917
Brugia malayi Myosin head containing protein 0.0013 0.0008 0.0019
Echinococcus granulosus dro:myosuppressin receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0057 0.041
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) G-protein coupled receptor 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0034 0.0077
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0143 0.0402 0.092
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0015 0.0006
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.021 0.0601 0.1378
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0418
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1035 0.3083 0.7293
Onchocerca volvulus Neuropeptide F receptor homolog 0.0165 0.0467 0.3379
Schistosoma mansoni axis inhibition protein axin 0.0237 0.0682 0.1564
Brugia malayi 6-phosphofructokinase 0.0106 0.029 0.0664
Echinococcus granulosus g-protein coupled receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0095
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0014 0.0088
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0083 0.1588
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0015 0.0091
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0 0.0001
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.029 0.0686
Echinococcus multilocularis regulator of G protein signaling 0.0237 0.0682 0.0682
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0112 0.0308 0.0308
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0143 0.0402 0.095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0004 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0196 0.1419
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0137 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0034 0.0077
Schistosoma mansoni hypothetical protein 0.0027 0.0052 0.0119
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0014 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi protein C24B5.3 0.0013 0.0008 0.0019
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0143 0.0402 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.031 0.0733
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0122 0.2479
Onchocerca volvulus 0.0053 0.0131 0.0946
Echinococcus multilocularis myotubularin protein 13 0.0022 0.0036 0.0036
Brugia malayi hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Guanylyl cyclase protein 23 0.0025 0.0045 0.0103
Entamoeba histolytica p21-activated kinase 0.0028 0.0054 0.0632
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Schistosoma mansoni lipoxygenase 0.002 0.003 0.0068
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi G protein-coupled receptor F59B2.13 0.0165 0.0467 0.1069
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0233 0.0672 0.1539
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0022 0.0036 0.0884
Onchocerca volvulus 0.0013 0.0008 0.0059
Plasmodium falciparum phosphodiesterase gamma, putative 0.0143 0.0402 1
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0018 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0015 0.0006
Loa Loa (eye worm) RNA binding protein 0.0062 0.0155 0.0355
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0142 0.158
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0058 0.0166
Trichomonas vaginalis centaurin gamma, putative 0.0022 0.0036 0.0257
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.2059 0.472
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0036 0.0036
Schistosoma mansoni fibrocystin l 0.0012 0.0006 0.0014
Onchocerca volvulus 0.0165 0.0467 0.3379
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0028 0.0054 0.0578
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0034 0.0078
Brugia malayi hypothetical protein 0.0011 0.0004 0.0008
Onchocerca volvulus 0.006 0.015 0.1082
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0015 0.0091
Brugia malayi hypothetical protein 0.0027 0.0052 0.0118
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Echinococcus granulosus tar DNA binding protein 0.0062 0.0155 0.0368
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Echinococcus granulosus bloom syndrome protein 0.0021 0.0033 0.0077
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus regulator of G protein signaling 3 0.0237 0.0682 0.1614
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0038 0.0083 0.0601
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0165 0.0467 0.107
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.0253 0.0598
Leishmania major GTP-binding protein, putative 0.0024 0.0042 0.0438
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0014 0.0125
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0263 0.0762 0.1748
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0142 0.158
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0034 0.0077
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0042 0.0118
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0285 0.0828 0.0828
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0014 0.0041
Brugia malayi Protein kinase domain containing protein 0.0038 0.0084 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0034 0.0448
Schistosoma mansoni n-acetylgalactosaminyltransferase 0.002 0.003 0.0068
Echinococcus multilocularis beta adrenergic receptor kinase 0.1119 0.3337 0.3337
Giardia lamblia Hypothetical protein 0.0143 0.0402 0.1143
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Brugia malayi Cytochrome P450 family protein 0.0032 0.0066 0.0151
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Treponema pallidum NADH oxidase 0.0033 0.0068 0.0604
Brugia malayi nuclear hormone receptor 0.0021 0.0034 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Echinococcus granulosus allatostatin A receptor 0.0165 0.0467 0.1104
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.029 0.0665
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0241 0.0696 0.1596
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0214 0.0615 0.893
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Brugia malayi Melibiase family protein 0.0075 0.0196 0.0448
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0057 0.016
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Schistosoma mansoni axis inhibition protein axin 0.0237 0.0682 0.1564
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.029 0.328
Schistosoma mansoni biogenic amine (5HT) receptor 0.0165 0.0467 0.107
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0 0.0001
Plasmodium falciparum phd finger protein, putative 0.0029 0.0058 0.1455
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Schistosoma mansoni metabotropic glutamate receptor 0.0194 0.0554 0.1269
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0156 0.0443
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis exocyst complex component 2 0.0012 0.0006 0.0006
Brugia malayi Importin beta-1 subunit 0.0032 0.0067 0.0154
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0004 0.0004
Schistosoma mansoni trimeric G-protein alpha o subunit 0.001 0 0.0001
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0067 0.0191
Echinococcus granulosus Ankyrin 0.0032 0.0067 0.0159
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0022 0.0036 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0241 0.1744
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0122 0.1671
Echinococcus multilocularis beta 1,4 N acetylgalactosaminyltransferase 0.0048 0.0116 0.0116
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Plexin repeat family protein 0.0065 0.0166 0.038
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Loa Loa (eye worm) cytohesin 3 0.0022 0.0036 0.0081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) PXA domain-containing protein 0.0237 0.0682 0.1563
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0014 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus granulosus transcription factor collier 0.0012 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Onchocerca volvulus 0.0165 0.0467 0.3379
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1415 0.4227 0.4227
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0014 0.0088
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0165 0.0467 0.107
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0083 0.0913
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0004 0.0042
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Echinococcus granulosus beta 1 syntrophin 0.0022 0.0036 0.0084
Plasmodium falciparum glutathione reductase 0.0033 0.0068 0.1697
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trypanosoma brucei unspecified product 0.0015 0.0014 0.0121
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.0253 0.2854
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0034 0.0077
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Plasmodium vivax phosphodiesterase gamma, putative 0.0143 0.0402 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0214 0.0615 0.8939
Echinococcus granulosus DCC interacting protein 13 beta 0.0022 0.0036 0.0084
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0036 0.0081
Onchocerca volvulus 0.0165 0.0467 0.3379
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Onchocerca volvulus 0.0015 0.0015 0.0104
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0015 0.0042
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0066 0.0475
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0057 0.016
Brugia malayi PHD-finger family protein 0.0029 0.0058 0.0133
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Brugia malayi regulator of G-protein signaling rgs-7 0.0237 0.0682 0.1563
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0067 0.0067
Brugia malayi hypothetical protein 0.0113 0.031 0.0709
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0034 0.0077
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0034 0.0081
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Brugia malayi plexin A 0.0077 0.0202 0.0462
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.001 0 0.0002
Brugia malayi Cytochrome P450 family protein 0.0036 0.0078 0.0177
Loa Loa (eye worm) galactosyltransferase 0.0184 0.0524 0.1202
Brugia malayi protein C24B5.3 0.0013 0.0008 0.0019
Echinococcus multilocularis neuropeptide Y receptor 0.0165 0.0467 0.0467
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Brugia malayi jmjC domain containing protein 0.0037 0.0082 0.0188
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Plasmodium falciparum oxysterol-binding protein, putative 0.0022 0.0036 0.0884
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0143 0.0402 0.0402
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0015 0.0015
Brugia malayi phosphofructokinase 0.0106 0.029 0.0664
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0083 0.0913
Trichomonas vaginalis protein transport protein sec7, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0122 0.1426
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0068 0.1697
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0153
Schistosoma mansoni hypothetical protein 0.002 0.003 0.0068
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0165 0.0467 0.1104
Echinococcus multilocularis calcium activated potassium channel 0.0011 0.0004 0.0004
Trypanosoma cruzi Protein kinase B 0.0028 0.0054 0.0578
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0067 0.0774
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus multilocularis calcium dependent secretion activator 1 0.0022 0.0036 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi metabotropic glutamate receptor type 2 0.0113 0.031 0.0709
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi intermediate filament protein 0.0053 0.0131 0.0299
Schistosoma mansoni survival motor neuron protein 0.0049 0.0116 0.0266
Giardia lamblia PHD finger protein 15 0.0029 0.0058 0.0166
Onchocerca volvulus 0.0015 0.0015 0.0104
Echinococcus granulosus neuropeptides capa receptor 0.0165 0.0467 0.1104
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0083 0.1102
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0083 0.0913
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Echinococcus granulosus transient receptor potential cation channel 0.0168 0.0476 0.1126
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0028 0.0054 0.1346
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0165 0.0467 0.107
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Echinococcus granulosus beta-adrenergic receptor kinase 0.1119 0.3337 0.7895
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi Galactosyltransferase family protein 0.0184 0.0524 0.1202
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.0253 0.0579
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Toxoplasma gondii protein kinase domain-containing protein 0.0028 0.0054 0.0153
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0034 0.0081
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0022 0.0036 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Schistosoma mansoni loxhd1 0.002 0.003 0.0068
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0022 0.0036 0.0084
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0059 0.0149 0.034
Echinococcus multilocularis neuropeptide s receptor 0.0165 0.0467 0.0467
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0058 0.0138
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.004 0.0091 0.0207
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0078 0.0911
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni plexin 0.0065 0.0166 0.038
Schistosoma mansoni hypothetical protein 0.0029 0.0056 0.0129
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0022 0.0036 0.0036
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0068 0.1697
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.092
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0015 0.0091
Echinococcus multilocularis beta 1,4 galactosyltransferase 7 0.0048 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0206 0.0591 0.1354
Toxoplasma gondii Oxysterol-binding protein 0.0022 0.0036 0.0101
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0022 0.0036 0.0036
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0194 0.0554 0.0554
Echinococcus granulosus GRB2 associated binding protein 3 0.0022 0.0036 0.0084
Leishmania major extracellular receptor, putative 0.0022 0.0036 0.0368
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0034 0.0078
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0 0.0000046864
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0034 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.3337 0.765
Loa Loa (eye worm) TYRA-2 protein 0.0165 0.0467 0.1069
Schistosoma mansoni beta-14-galactosyltransferase 0.0029 0.0056 0.0129
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0257 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0142 0.0325
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0071
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0057 0.5917
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.009 0.0241 0.0551
Echinococcus multilocularis allatostatin A receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0045
Toxoplasma gondii thioredoxin reductase 0.0094 0.0253 0.0716
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0068 0.7691
Loa Loa (eye worm) PH domain-containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0686 0.0686
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0014 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0165 0.0467 0.0467
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0143 0.0402 0.095
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus granulosus sex peptide receptor 0.0165 0.0467 0.1104
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0213 0.061 0.1399
Brugia malayi nuclear receptor NHR-67 0.001 0 0.0000046864
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0 0.0001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0057 0.141
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0034 0.0077
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0165 0.0467 0.1069
Schistosoma mansoni beta-14-galactosyltransferase 0.0184 0.0524 0.1202
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0112 0.0308 0.073
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0103
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0093 0.0093
Echinococcus granulosus Protein patched homolog 1 0.009 0.0241 0.0569
Loa Loa (eye worm) glutathione reductase 0.0094 0.0253 0.0579
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0066 0.0151
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0068 0.1238
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Plasmodium falciparum PH domain-containing protein, putative 0.0022 0.0036 0.0884
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0165 0.0467 0.3379
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0015 0.0004
Loa Loa (eye worm) glutamate receptor 0.0091 0.0244 0.0559
Brugia malayi RNA, U transporter 1 0.0092 0.0247 0.0565
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Plasmodium falciparum calcium-dependent protein kinase 7 0.0028 0.0054 0.1346
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0877 1
Brugia malayi CHE-14 protein 0.009 0.0241 0.0551
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0083 0.2075
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.104
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.029 0.328
Brugia malayi Oxysterol binding protein 0.0022 0.0036 0.0081
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Echinococcus granulosus plexin a4 0.0077 0.0202 0.0477
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0067 0.0732
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0068 0.0739
Echinococcus granulosus dnaJ subfamily B 0.0449 0.1321 0.3125
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni nuclear hormone receptor 0.001 0 0.0001
Giardia lamblia O-linked GlcNAc transferase 0.0023 0.004 0.0114
Trypanosoma brucei rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0155 0.0155
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.011 0.0301 0.069
Loa Loa (eye worm) nuclear hormone receptor 0.001 0 0.0000046864
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus multilocularis actin binding protein anillin 0.0022 0.0036 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0238 0.0687 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0 0.0000046864
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0399 0.4532
Leishmania major cytochrome p450-like protein 0.0032 0.0066 0.0719
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0022 0.0036 0.0257
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.004 0.0091 0.0209
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0022 0.0036 0.0036
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0686 0.1623
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0083 0.2075
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi A-kinase anchor protein 10, precursor 0.0237 0.0682 0.1563
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Entamoeba histolytica cell surface protease gp63, putative 0.0012 0.0006 0.007
Trichomonas vaginalis centaurin/arf, putative 0.0022 0.0036 0.0257
Brugia malayi Sema domain containing protein 0.0027 0.0052 0.0118
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0102
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0402 0.5769
Echinococcus multilocularis expressed protein 0.0237 0.0682 0.0682
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Brugia malayi hypothetical protein 0.001 0 0.0000046864
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi hypothetical protein 0.0022 0.0036 0.0081
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0015 0.0107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0133
Plasmodium vivax SET domain protein, putative 0.006 0.015 0.3726
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni nuclear receptor 0.001 0 0.0001
Echinococcus multilocularis musashi 0.0053 0.0131 0.0131
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0165 0.0467 0.1069
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0356
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.001 0 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Schistosoma mansoni intermediate filament proteins 0.0053 0.0131 0.03
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0078 0.9166
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus receptor type guanylyl cyclase 0.0025 0.0045 0.0107
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0178 0.0408
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0084 0.2081
Echinococcus granulosus ankyrin repeat protein 0.0163 0.0461 0.1091
Schistosoma mansoni tyrosine kinase 0.0025 0.0045 0.0104
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0165 0.0467 0.3379
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0066 0.0151
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0221 0.0506
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0034 0.0077
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0237 0.0682 0.4944
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0125
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0049 0.0356
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus multilocularis GRB2 associated binding protein 3 0.0022 0.0036 0.0036
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0 0.0000046864
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0057 0.0662
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0022 0.0036 0.0257
Echinococcus granulosus tm gpcr rhodopsin 0.0165 0.0467 0.1104
Brugia malayi Presenilin-like protein At2g29900 0.0085 0.0224 0.0514
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.001 0 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.0165 0.0467 0.1104
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Loa Loa (eye worm) presenilin spe-4 0.0085 0.0224 0.0514
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus biogenic amine 5HT receptor 0.0165 0.0467 0.1104
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.003 0.003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0412 0.1209 0.2771
Echinococcus multilocularis lamin 0.0053 0.0131 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0066 0.015
Echinococcus multilocularis lamin dm0 0.0053 0.0131 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.3337 0.765
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0143 0.0402 0.0402
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0034 0.008
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0068 0.0193
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0083 0.0604
Schistosoma mansoni myosin xvIII 0.0165 0.0467 0.107
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0066 0.015
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0012 0.0309
Brugia malayi putative neuropeptide receptor 0.0165 0.0467 0.1069
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0034 0.0081
Schistosoma mansoni hypothetical protein 0.0027 0.0052 0.0119
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0014
Schistosoma mansoni hypothetical protein 0.0113 0.031 0.071
Toxoplasma gondii hypothetical protein 0.0048 0.0116 0.0328
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Brugia malayi hypothetical protein 0.001 0 0.0000046864
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0237 0.0682 0.1564
Onchocerca volvulus 0.0022 0.0036 0.0256
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0739
Toxoplasma gondii melibiase subfamily protein 0.0112 0.0308 0.0874
Brugia malayi neuropeptide F receptor 0.0165 0.0467 0.1069
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0068 0.0739
Loa Loa (eye worm) hypothetical protein 0.006 0.015 0.0342
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0165 0.0467 0.107
Echinococcus multilocularis oxysterol binding protein 3 0.0022 0.0036 0.0036
Trichomonas vaginalis centaurin/arf, putative 0.0022 0.0036 0.0257
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0 0.0001
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0 0.0001
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0066 0.0156
Onchocerca volvulus 0.0022 0.0036 0.0255
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Loa Loa (eye worm) beta-1,4-galactosyltransferase VII 0.0048 0.0116 0.0265
Schistosoma mansoni phenylalanine decarboxylase 0.0048 0.0116 0.0265
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Echinococcus granulosus pleckstrin y domain containing family A 0.0022 0.0036 0.0084
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.029 0.0664
Brugia malayi Patched protein homolog 1 0.0013 0.0008 0.0019
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0066 0.1196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0165 0.0467 0.107
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0221 0.0506
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0034 0.0246
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0143 0.0402 0.0402
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Echinococcus multilocularis regulator of G protein signaling 7 0.0237 0.0682 0.0682
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.002 0.003 0.0068
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0068 0.0878
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0068 0.0739
Onchocerca volvulus 0.002 0.003 0.0214
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0 0.0001
Schistosoma mansoni dynamin 0.0022 0.0036 0.0081
Mycobacterium ulcerans hypothetical protein 0.0159 0.0448 1
Echinococcus multilocularis snurportin 1 0.0345 0.1008 0.1008
Brugia malayi Patched related family protein 12 0.0013 0.0008 0.0019
Echinococcus granulosus pdz domain containing protein 0.0022 0.0036 0.0084
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0 0.0001
Brugia malayi tailless protein 0.001 0 0.0000046864
Onchocerca volvulus Protein patched homolog 0.0013 0.0008 0.0059
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0022 0.0036 0.0036
Brugia malayi Patched related family protein 4 0.0013 0.0008 0.0019
Plasmodium vivax patched family protein, putative 0.0013 0.0008 0.0209
Brugia malayi Dynamin 0.0022 0.0036 0.0081
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0022 0.0036 0.0084
Echinococcus granulosus serotonin receptor 0.0165 0.0467 0.1104
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Brugia malayi Syntrophin-1 0.0022 0.0036 0.0081
Echinococcus granulosus neuropeptide receptor 0.0165 0.0467 0.1104
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0122 0.2479
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Onchocerca volvulus 0.0022 0.0036 0.0255
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0034 0.0081
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0165 0.0467 0.0467
Onchocerca volvulus Alhambra homolog 0.0029 0.0058 0.0421
Schistosoma mansoni syntrophin 0.0022 0.0036 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0302 0.0878 0.2012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus granulosus O glycosyltransferase 0.004 0.0091 0.0216
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0057 0.141
Trypanosoma brucei PH domain containing protein, putative 0.0022 0.0036 0.0366
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.029 0.6358
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0302 0.0878 0.2012
Brugia malayi nuclear receptor RXR 0.0011 0.0004 0.0008
Leishmania major DNA polymerase eta, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis dro:myosuppressin receptor 0.0165 0.0467 0.0467
Trichomonas vaginalis kinesin light chain, putative 0.0022 0.0036 0.026
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0022 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Brugia malayi glutathione reductase 0.0094 0.0253 0.0579
Loa Loa (eye worm) hypothetical protein 0.009 0.0241 0.0551
Brugia malayi Plekhf2 protein 0.0022 0.0036 0.0081
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.1321 0.1321
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Brugia malayi steroid hormone receptor 0.0021 0.0034 0.0077
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0068 0.0739
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Onchocerca volvulus 0.0165 0.0467 0.3379
Schistosoma mansoni alpha-1 adrenergic receptor 0.0165 0.0467 0.107
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0233 0.0672 0.0672
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Schistosoma mansoni beta-14-galactosyltransferase 0.0184 0.0524 0.1202
Toxoplasma gondii AtPH1 family protein 0.0022 0.0036 0.0101
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0402 0.895
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0014 0.0088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0022 0.0036 0.0084
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0034 0.0081
Echinococcus granulosus polypeptide N acetylgalactosaminyltransferase 0.002 0.003 0.0071
Echinococcus granulosus cytohesin 1 0.0022 0.0036 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Echinococcus granulosus fmrfamide receptor 0.0165 0.0467 0.1104
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0015 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Loa Loa (eye worm) oxidoreductase 0.0015 0.0015 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.005
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0015 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0078 0.0564
Brugia malayi RE15519p 0.0165 0.0467 0.1069
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0078 0.0177
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0078 0.1462
Leishmania major protein kinase, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0034 0.0077
Leishmania major hypothetical protein, conserved 0.0143 0.0402 0.4556
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Brugia malayi Metabotropic glutamate receptor precursor. 0.0232 0.0667 0.1528
Echinococcus multilocularis plexin a4 0.0077 0.0202 0.0202
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0152 0.0349
Onchocerca volvulus outspread protein homolog 0.0022 0.0036 0.0255
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0233 0.0672 0.0672
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus microtubule associated protein 2 0.0694 0.2059 0.4872
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0083 0.019
Loa Loa (eye worm) RecQ helicase 0.0021 0.0033 0.0074
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus regulator of G protein signaling 7 0.0237 0.0682 0.1614
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis Metazoa galactosyltransferase 0.0184 0.0524 0.0524
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0056 0.0128
Echinococcus granulosus semaphorin 1A 0.0027 0.0052 0.0123
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Schistosoma mansoni plexin 0.0038 0.0084 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0034 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0048 0.0116 0.0265
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0131 0.0299
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0233 0.0672 0.1539
Onchocerca volvulus 0.0165 0.0467 0.3379
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Echinococcus multilocularis hypothetical protein 0.0027 0.0052 0.0052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.0467
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0165 0.0467 0.0467
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0049 0.0521
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis fmrfamide receptor 0.0165 0.0467 0.0467
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0034 0.0348
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Brugia malayi hypothetical protein 0.0237 0.0682 0.1563
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0221 0.0523
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0034 0.0034
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0083 0.0604
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0015 0.0033
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0067 0.0855
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Onchocerca volvulus Protein patched homolog 0.0013 0.0008 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0237 0.0682 0.1564
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Schistosoma mansoni inositol monophosphatase 0.0036 0.0078 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis cpg binding protein 0.0033 0.007 0.007
Loa Loa (eye worm) AGC/AKT protein kinase 0.0028 0.0054 0.0123
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0056 0.0128
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0034 0.0077
Echinococcus multilocularis G-protein coupled receptor, putative 0.0165 0.0467 0.0467
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0257 0.0257
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.015 0.0424
Echinococcus multilocularis somatostatin receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis Ankyrin 0.0032 0.0067 0.0067
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0022 0.0036 0.0081
Onchocerca volvulus 0.0013 0.0008 0.0059
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.146 0.4362 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0112 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Plasmodium falciparum LCCL domain-containing protein 0.002 0.003 0.0744
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0 0.0001
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis pleckstrin y domain containing family A 0.0022 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.0025 0.0045 0.0104
Brugia malayi MAP kinase sur-1 0.0057 0.0142 0.0324
Plasmodium falciparum thioredoxin reductase 0.0033 0.0068 0.1697
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Echinococcus granulosus G protein coupled receptor kinase 1 0.0883 0.2625 0.621
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus granulosus lamin 0.0053 0.0131 0.031
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0025 0.0045 0.0326
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0034 0.0374
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0034 0.0077
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0004 0.001
Echinococcus multilocularis Metazoa galactosyltransferase 0.0156 0.0439 0.0439
Schistosoma mansoni importin beta-1 0.0032 0.0067 0.0155
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.0253 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0022 0.0036 0.0255
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0143 0.0402 0.092
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis transient receptor potential cation channel 0.0169 0.0477 0.0477
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Echinococcus granulosus metabotropic glutamate receptor 5 0.0285 0.0828 0.1958
Trichomonas vaginalis centaurin beta, putative 0.0022 0.0036 0.0257
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0022 0.0036 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0389 0.114 0.2612
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.0855 0.2433
Entamoeba histolytica tyrosin kinase, putative 0.0015 0.0016 0.0182
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0142 0.0401
Schistosoma mansoni neuropeptide f receptor 76f 0.0165 0.0467 0.107
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0165 0.0467 0.1069
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0014 0.0088
Onchocerca volvulus Putative zinc finger protein 0.0022 0.0036 0.0255
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0084 1
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni cytochrome P450 0.0015 0.0014 0.0033
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.004 0.0091 0.0207
Toxoplasma gondii hypothetical protein 0.0022 0.0036 0.0101
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0004
Schistosoma mansoni z-protein (S1r protein) 0.0237 0.0682 0.1564
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0034 0.0077
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0082 0.0189
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0165 0.0467 0.1069
Brugia malayi follicle stimulating hormone receptor 0.0389 0.114 0.2612
Echinococcus multilocularis expressed conserved protein 0.0197 0.0562 0.0562
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0119
Schistosoma mansoni cpg binding protein 0.0032 0.0065 0.0149
Brugia malayi Cytochrome P450 family protein 0.0032 0.0066 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Plasmodium falciparum lipid/sterol:H+ symporter 0.0013 0.0008 0.0209
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0068 0.0155
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0257 0.059
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1178 0.3514 0.3514
Toxoplasma gondii glycosyl transferase 0.002 0.003 0.0085
Echinococcus multilocularis O glycosyltransferase 0.004 0.0091 0.0091
Toxoplasma gondii N-acetylgalactosaminyl transferase 0.002 0.003 0.0085
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0022 0.0036 0.0081
Mycobacterium tuberculosis Probable reductase 0.0214 0.0615 0.8939
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0034 0.0034
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0058 0.0134
Schistosoma mansoni nuclear receptor 0.001 0 0.0001
Schistosoma mansoni netrin receptor unc5 0.0032 0.0066 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0142 0.0335
Echinococcus multilocularis serotonin receptor 0.0165 0.0467 0.0467
Echinococcus granulosus Rho GTPase activating protein 24 0.0022 0.0036 0.0084
Echinococcus granulosus cpg binding protein 0.0033 0.007 0.0167
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0161
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.003
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1178 0.3514 0.8314
Brugia malayi Serotonin receptor 0.0165 0.0467 0.1069
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0 0.0001
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Brugia malayi hypothetical protein 0.002 0.003 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus serine/threonine protein kinase 0.0028 0.0054 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0034 0.0077
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Onchocerca volvulus 0.0021 0.0034 0.0245
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0084 0.1594
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.029 0.415
Schistosoma mansoni myotubularin-related protein 0.0022 0.0036 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0257 0.059
Onchocerca volvulus 0.0022 0.0036 0.0255
Entamoeba histolytica Ran family GTPase 0.0024 0.0042 0.0489
Schistosoma mansoni serine/threonine protein kinase 0.146 0.4362 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0156
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.001 0 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0083 0.0786
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0237 0.0682 0.1614
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0068 0.0739
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0034 0.0077
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0015 0.0091
Toxoplasma gondii hypothetical protein 0.0049 0.0116 0.033
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi Oxysterol-binding protein 0.0022 0.0036 0.0081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Echinococcus granulosus neuropeptide receptor A26 0.0165 0.0467 0.1104
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.031 0.031
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0196 0.0449
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0034 0.0448
Loa Loa (eye worm) hypothetical protein 0.0052 0.0128 0.0293
Schistosoma mansoni inositol monophosphatase 0.0036 0.0078 0.0178
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Echinococcus multilocularis ankyrin repeat protein 0.0163 0.0461 0.0461
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Schistosoma mansoni centaurin alpha 0.0022 0.0036 0.0081
Echinococcus granulosus myotubularin protein 13 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0016 0.0182
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0059 0.0149 0.034
Echinococcus multilocularis GPCR, family 2 0.0096 0.0257 0.0257
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0028 0.0054 0.0578
Schistosoma mansoni biogenic amine (5HT) receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0165 0.0467 0.1069
Onchocerca volvulus 0.0065 0.0166 0.1199
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Brugia malayi RNA binding protein 0.0062 0.0155 0.0355
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0154
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0143 0.0402 0.095
Echinococcus granulosus glutamate receptor 2 0.0022 0.0036 0.0084
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0022 0.0036 0.0366
Echinococcus granulosus expressed protein 0.001 0 0.0001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0082 0.0189
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0007 0.0041
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Trichomonas vaginalis hypothetical protein 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0004 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0143 0.0402 0.095
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Plasmodium falciparum importin beta, putative 0.0032 0.0067 0.168
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.1104
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Echinococcus granulosus beta 14 galactosyltransferase 7 0.0048 0.0116 0.0274
Toxoplasma gondii exonuclease III APE 0.0038 0.0083 0.0236
Leishmania major importin beta-1 subunit, putative 0.0026 0.0049 0.0521
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.029 0.4098
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0028 0.0054 0.0153
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0014 0.0088
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0143 0.0402 0.0402
Echinococcus granulosus Ribosomal protein L34a 0.0136 0.0379 0.0896
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0082 0.0195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.0467
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0015 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi hypothetical protein 0.0238 0.0686 0.1572
Loa Loa (eye worm) hypothetical protein 0.0238 0.0686 0.1572
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0022 0.0036 0.0084
Schistosoma mansoni hypothetical protein 0.0038 0.0084 0.0193
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0034 0.0078
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.029 0.328
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor E75 0.001 0 0.0000046864
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0068
Onchocerca volvulus 0.0015 0.0015 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trypanosoma brucei trypanothione reductase 0.0094 0.0253 0.2854
Echinococcus multilocularis neuropeptides capa receptor 0.0165 0.0467 0.0467
Onchocerca volvulus 0.0469 0.1381 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0196 0.0449
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0034 0.0077
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Brugia malayi 6-phosphofructokinase 0.0106 0.029 0.0664
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus dna polymerase eta 0.0021 0.0034 0.008
Echinococcus granulosus Niemann Pick C1 protein 0.0299 0.0871 0.206
Loa Loa (eye worm) rho-GTPase-activating 0.0022 0.0036 0.0081
Echinococcus granulosus axis inhibition protein axin 0.0237 0.0682 0.1614
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi nuclear receptor NHR-88 0.0021 0.0034 0.0077
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0033
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0221 0.0523
Echinococcus granulosus tm gpcr rhodopsin 0.1415 0.4227 1
Onchocerca volvulus 0.0165 0.0467 0.3379
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0022 0.0036 0.0081
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0057 0.141
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1223 0.365 0.8368
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0 0.0001
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni rho gtpase activating protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Doublecortin family protein 0.002 0.003 0.0068
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0165 0.0467 0.1069
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Onchocerca volvulus 0.002 0.003 0.0214
Brugia malayi PHD-finger family protein 0.0011 0.0004 0.0009
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.003 0.0071
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0078 0.0184
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus granulosus nmda type glutamate receptor 0.0022 0.0036 0.0084
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0237 0.0682 0.1563
Echinococcus multilocularis Niemann Pick C1 protein 0.0299 0.0871 0.0871
Trypanosoma brucei unspecified product 0.0021 0.0034 0.0348
Plasmodium vivax glutathione reductase, putative 0.0094 0.0253 0.6296
Brugia malayi MAX-1A 0.0022 0.0036 0.0081
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.1119 0.3337 0.765
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0068 0.1697
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0005 0.012
Brugia malayi nuclear hormone receptor 0.001 0 0.0000046864
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Schistosoma mansoni vav2 0.0022 0.0036 0.0081
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Loa Loa (eye worm) hypothetical protein 0.0083 0.0221 0.0506
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1035 0.3083 0.3083
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0165 0.0467 0.0467
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0022 0.0036 0.0366
Loa Loa (eye worm) galactosyltransferase 0.0048 0.0116 0.0265
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0034 0.0245
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0022 0.0036 0.0415
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0259 0.0613
Loa Loa (eye worm) hypothetical protein 0.1178 0.3514 0.8056
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Trypanosoma brucei protein kinase, putative 0.0057 0.0142 0.158
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0083 0.0237
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0034 0.0078
Echinococcus multilocularis axis inhibition protein axin 0.0237 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Brugia malayi Cytohesin 3 0.0022 0.0036 0.0081
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0165 0.0467 0.1069
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0034 0.0081
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0066 0.0151
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0022 0.0036 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0028 0.0054 0.0578
Mycobacterium tuberculosis Probable oxidoreductase 0.0238 0.0687 1
Schistosoma mansoni dynamin 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0142 0.158
Brugia malayi Calcitonin receptor-like protein seb-1 0.0302 0.0878 0.2012
Loa Loa (eye worm) inositol-1 0.0036 0.0078 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Brugia malayi hypothetical protein 0.0027 0.0052 0.0118
Trypanosoma brucei hypothetical protein, conserved 0.0143 0.0402 0.4556
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0022 0.0036 0.0884
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.029 0.3254
Echinococcus granulosus oxysterol binding protein 1 0.0022 0.0036 0.0084
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0054 0.0578
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Brugia malayi conserved hypotetical protein 0.001 0 0.0000046864
Entamoeba histolytica presenilin 1 peptidase, putative 0.0241 0.0696 0.8144
Echinococcus granulosus snurportin 1 0.0345 0.1008 0.2386
Echinococcus granulosus expressed protein 0.0237 0.0682 0.1614
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0022 0.0036 0.0415
Echinococcus granulosus hypothetical protein 0.0165 0.0467 0.1104
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0034 0.0078
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0141 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus multilocularis regulator of G protein signaling 3 0.0237 0.0682 0.0682
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0048 0.0113
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Brugia malayi Niemann-Pick C1 protein precursor 0.0209 0.06 0.1376
Brugia malayi hypothetical protein 0.0011 0.0004 0.0008
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0015 0.0042
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1178 0.3514 0.8056
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Brugia malayi beta-1,4-galactosyltransferase VII 0.0048 0.0116 0.0265
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0036 0.0036
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0165 0.0467 0.1104
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0048 0.0048
Echinococcus granulosus presenilin 0.0241 0.0696 0.1647
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus atrial natriuretic peptide receptor 0.0022 0.0036 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi Pleckstrin Homology Domain 0.0022 0.0036 0.0081
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0022 0.0036 0.0884
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0015 0.0006
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Schistosoma mansoni lamin 0.0053 0.0131 0.03
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.015 0.0354
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0221 0.0506
Brugia malayi Pre-SET motif family protein 0.006 0.015 0.0342
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0015 0.0006
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0014 0.0088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0233 0.0672 0.1589
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus tachykinin peptides receptor 99D 0.0165 0.0467 0.1104
Onchocerca volvulus 0.0032 0.0065 0.0469
Echinococcus granulosus Oxysterol binding protein 11 0.0022 0.0036 0.0084
Echinococcus granulosus expressed conserved protein 0.0197 0.0562 0.133
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0082 0.0188
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Brugia malayi hypothetical protein 0.0016 0.0019 0.0044
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0066 0.0719
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.029 0.029
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Brugia malayi Inositol-1 0.0036 0.0078 0.0178
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Toxoplasma gondii hypothetical protein 0.0013 0.0008 0.0024
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0068
Echinococcus multilocularis DCC interacting protein 13 beta 0.0022 0.0036 0.0036
Schistosoma mansoni polycystin 1-related 0.002 0.003 0.0068
Schistosoma mansoni ran 0.0024 0.0042 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) oxysterol binding protein 0.0022 0.0036 0.0081
Brugia malayi CXXC zinc finger family protein 0.0032 0.0065 0.0148
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium ulcerans hypothetical protein 0.0016 0.0018 0.007
Echinococcus granulosus RUN 0.002 0.003 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0 0.0001
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0036 0.0081
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0053 0.0131 0.0299
Schistosoma mansoni hypothetical protein 0.0032 0.0066 0.0151
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.001 0 0.0002
Schistosoma mansoni ap endonuclease 0.0038 0.0083 0.0191
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0054 0.0578
Brugia malayi jmjC domain containing protein 0.0096 0.0259 0.0594
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1178 0.3514 0.8314
Brugia malayi Serotonin receptor 0.0165 0.0467 0.1069
Echinococcus multilocularis neuropeptides capa receptor 0.0165 0.0467 0.0467
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0257 0.0609
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Toxoplasma gondii phosphatidylinositol transfer protein 0.0022 0.0036 0.0101
Onchocerca volvulus 0.0049 0.0116 0.0839
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Schistosoma mansoni semaphorin 5-related 0.0027 0.0052 0.0119
Brugia malayi Presenilin family protein 0.0241 0.0696 0.1595
Onchocerca volvulus 0.0165 0.0467 0.3379
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0015 0.0091
Echinococcus multilocularis Rho GTPase activating protein 24 0.0022 0.0036 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0034 0.0078
Schistosoma mansoni cpg binding protein 0.0033 0.007 0.0161
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0 0.0001
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0014 0.0034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0116 0.0266
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus neuropeptide receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Schistosoma mansoni zinc finger protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.005 0.012 0.0274
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0165 0.0467 0.0467
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0034 0.0081
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0095
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0083 0.0197
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0058 0.0166
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0034 0.0397
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0143 0.0402 0.095
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0214 0.0615 0.8939
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0855 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0035 0.0078
Echinococcus multilocularis regulator of G protein signaling 3 0.0237 0.0682 0.0682
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0034 0.0077
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0877 1
Leishmania major folate/biopterin transporter, putative 0.0028 0.0054 0.0578
Echinococcus multilocularis oxysterol binding protein 1 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0004 0.0026
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.015 0.015
Trypanosoma brucei unspecified product 0.0015 0.0014 0.0121
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0014 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Onchocerca volvulus 0.0022 0.0036 0.0255
Schistosoma mansoni neuropeptide F-like receptor 0.0165 0.0467 0.107
Brugia malayi TBC domain containing protein 0.0022 0.0036 0.0081
Echinococcus granulosus regulator of G protein signaling 3 0.0237 0.0682 0.1614
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0083 1
Brugia malayi hypothetical protein 0.0025 0.0046 0.0106
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0022 0.0036 0.0084
Echinococcus granulosus nuclear factor of activated T cells 5 0.0311 0.0906 0.2145
Brugia malayi IPT/TIG domain containing protein 0.0012 0.0006 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0233 0.0672 0.1589
Brugia malayi Dopamine receptor protein 2 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0046 0.0132
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Onchocerca volvulus 0.0165 0.0467 0.3379
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.0253 0.3601
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0014 0.0088
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Onchocerca volvulus 0.005 0.012 0.0866
Schistosoma mansoni hypothetical protein 0.0345 0.1008 0.2312
Loa Loa (eye worm) hypothetical protein 0.0065 0.0166 0.038
Schistosoma mansoni oxysterol-binding protein 1 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis presenilin 0.0241 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0042 0.0096
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0068
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Echinococcus multilocularis dna polymerase eta 0.0021 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0034 0.0078
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Echinococcus granulosus oxysterol binding protein 3 0.0022 0.0036 0.0084
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0058 0.1455
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0165 0.0467 0.1104
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) RGS-3 protein 0.0237 0.0682 0.1563
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.4556
Leishmania major hypothetical protein, conserved 0.0143 0.0402 0.4556
Echinococcus multilocularis RUN 0.002 0.003 0.003
Mycobacterium tuberculosis Probable dehydrogenase 0.0214 0.0615 0.8939
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Loa Loa (eye worm) neuropeptide F receptor 0.0165 0.0467 0.1069
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.015
Brugia malayi sulfakinin receptor protein 0.0165 0.0467 0.1069
Schistosoma mansoni growth hormone secretagogue receptor 0.0165 0.0467 0.107
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0165 0.0467 0.1069
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0238 0.0687 1
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0155 0.0355
Brugia malayi Patched related family protein 10 0.0013 0.0008 0.0019
Onchocerca volvulus Protein melted homolog 0.0022 0.0036 0.0255
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0038 0.0083 0.019
Echinococcus granulosus Niemann Pick C1 protein 0.0209 0.06 0.142
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Toxoplasma gondii hypothetical protein 0.0022 0.0036 0.0101
Echinococcus granulosus dna polymerase kappa 0.0021 0.0034 0.008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.015 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0143 0.0402 0.0402
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0084 0.2081
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0057 0.0161
Onchocerca volvulus 0.0022 0.0036 0.0255
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0022 0.0036 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0014 0.0088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0046 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Plasmodium falciparum thioredoxin reductase 0.0094 0.0253 0.6296
Loa Loa (eye worm) DR-78 0.001 0 0.0000046864
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Schistosoma mansoni DNA polymerase eta 0.0021 0.0034 0.0078
Schistosoma mansoni nuclear receptor nhr-48 0.001 0 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Giardia lamblia DINP protein human, muc B family 0.0021 0.0034 0.0097
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0402 0.5806
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0122 0.2479
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Schistosoma mansoni lipoxygenase 0.0056 0.0137 0.0315
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0034 0.0077
Brugia malayi G-protein coupled receptor 0.0165 0.0467 0.1069
Onchocerca volvulus 0.0165 0.0467 0.3379
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi hypothetical protein 0.0237 0.0682 0.1563
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0209 0.06 0.7022
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0004 0.0009
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica hypothetical protein 0.0028 0.0054 0.0632
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0057 0.141
Brugia malayi probable spectrin beta chain 0.0022 0.0036 0.0081
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0034 0.0245
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Brugia malayi hypothetical protein 0.002 0.003 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus calcium dependent secretion activator 1 0.0022 0.0036 0.0084
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0068 0.0194
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1223 0.365 0.8636
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0033 0.0033
Echinococcus granulosus neuropeptide Y receptor 0.0165 0.0467 0.1104
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi putative neuropeptide receptor NPR1 0.0165 0.0467 0.1069
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0142 0.158
Onchocerca volvulus 0.0015 0.0015 0.0104
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0034 0.0374
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0066 0.0151
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0032
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0034 0.0034
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0122 0.1598
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0574
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0054 0.0124
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Echinococcus granulosus neuropeptide s receptor 0.0165 0.0467 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Schistosoma mansoni cpg binding protein 0.0033 0.007 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Leishmania major serine/threonine-protein kinase a, putative 0.0028 0.0054 0.0578
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0015 0.0107
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0034 0.0077
Loa Loa (eye worm) glutamate receptor 0.0232 0.0667 0.1528
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0034 0.0034
Echinococcus granulosus glutamate receptor 2 0.0022 0.0036 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0855 1
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0015 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) cytochrome P450 0.0015 0.0014 0.0032
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0066 0.0719
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0192
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Toxoplasma gondii hypothetical protein 0.0085 0.0224 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0142 0.158
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0034 0.0034
Echinococcus granulosus Metazoa galactosyltransferase 0.0184 0.0524 0.1241
Brugia malayi Probable exocyst complex component Sec5 0.0012 0.0006 0.0013
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 0.0877 1
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.4556
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0126 0.1397
Echinococcus granulosus neuropeptide Y receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Brugia malayi regulator of G-protein signaling egl-10 0.0237 0.0682 0.1563
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0311 0.0906 0.0906
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Brugia malayi Melatonin receptor type 1A 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis beta 1 syntrophin 0.0022 0.0036 0.0036
Echinococcus granulosus peptide allatostatin:somatostatin 0.0165 0.0467 0.1104
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0065 0.0148
Trichomonas vaginalis set domain proteins, putative 0.0469 0.138 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.146 0.4362 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0012 0.0034
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Death domain containing protein 0.0032 0.0066 0.015
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.0855 1
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0125
Mycobacterium ulcerans hypothetical protein 0.005 0.0122 0.2479
Echinococcus multilocularis neuropeptide FF receptor 2 0.0165 0.0467 0.0467
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0068 0.0739
Giardia lamblia hypothetical protein 0.0143 0.0402 0.1143
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0042 0.0042
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0122 0.1671
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.4556
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Echinococcus granulosus semaphorin 5B 0.0027 0.0052 0.0123
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Tachykinin-like peptides receptor 99D 0.0165 0.0467 0.1069
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0142 0.0335
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Echinococcus multilocularis G protein coupled receptor 139 0.0165 0.0467 0.0467
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0143 0.0402 0.4556
Loa Loa (eye worm) neuropeptide F receptor 0.0165 0.0467 0.1069
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0015 0.0006
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0028 0.0054 0.0578
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0014
Echinococcus granulosus importin subunit beta 1 0.0032 0.0067 0.016
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0399 0.4532
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0142 0.0324
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Entamoeba histolytica hypothetical protein 0.0028 0.0054 0.0632
Echinococcus multilocularis peregrin 0.0029 0.0058 0.0058
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0143 0.0402 0.4556
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Schistosoma mansoni metabotropic glutamate receptor 0.0113 0.031 0.071
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0034 0.0034
Echinococcus granulosus tyrosine kinase 0.0025 0.0045 0.0107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1183 0.3529 1
Echinococcus multilocularis orexin receptor type 2 0.0165 0.0467 0.0467
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0077 0.0077
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0028 0.0054 0.0392
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0014 0.0088
Onchocerca volvulus 0.0013 0.0008 0.0059
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Echinococcus multilocularis axis inhibition protein axin 0.0237 0.0682 0.0682
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0015 0.0035
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0015 0.0006
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0022 0.0036 0.0036
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0022 0.0036 0.0255
Leishmania major protein kinase, putative 0.0028 0.0054 0.0578
Trichomonas vaginalis protein transport protein sec7, putative 0.0022 0.0036 0.0257
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0122 0.1426
Echinococcus multilocularis Ribosomal protein L34a 0.0136 0.0379 0.0379
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1223 0.365 0.365
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0093 0.022
Brugia malayi Dynamin 0.0022 0.0036 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Schistosoma mansoni glutamate receptor NMDA 0.0022 0.0036 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Brugia malayi Uncoordinated protein 104 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi G protein-coupled receptor 0.0165 0.0467 0.1069
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0034 0.0245
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis ran, putative 0.0024 0.0042 0.0303
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.029 0.0664
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis Ras associated and pleckstrin y 0.0022 0.0036 0.0036
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0022 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Echinococcus multilocularis receptor type guanylyl cyclase 0.0025 0.0045 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0155 0.0355
Schistosoma mansoni hypothetical protein 0.0206 0.0591 0.1354
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0034 0.0078
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0046 0.0492
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0034 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0068 0.1697
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Leishmania major trypanothione reductase 0.0094 0.0253 0.2854
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) sema domain-containing protein 0.0027 0.0052 0.0118
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0266
Brugia malayi orphan nuclear receptor NR2E1 0.001 0 0.0000046864
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.1035 0.3083 0.7067
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0142 0.158
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0042 0.104
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0054 0.0578
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0014 0.0088
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0165 0.0467 0.107
Onchocerca volvulus 0.005 0.0122 0.0881
Onchocerca volvulus 0.0022 0.0036 0.0255
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0 0.0001
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0057 0.0467
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0237 0.0682 0.1563
Onchocerca volvulus 0.0165 0.0467 0.3379
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0163 0.0461 0.1057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0083 0.0975
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0034 0.0078
Echinococcus multilocularis transcription factor collier 0.0012 0.0006 0.0006
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0066 0.0066
Echinococcus multilocularis nmda type glutamate receptor 0.0022 0.0036 0.0036
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0221 0.0506
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0143 0.0402 0.092
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0142 0.158
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0068 0.7691
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Brugia malayi nuclear receptor RXR 0.001 0 0.0000046864
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0083 0.0083
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Schistosoma mansoni oxysterol-binding protein 1 0.0022 0.0036 0.0081
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.019
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0237 0.0682 0.0682
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0046 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0034 0.0077
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0033 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Leishmania major mitochondrial DNA polymerase beta 0.0301 0.0877 1
Echinococcus granulosus somatostatin receptor 0.0165 0.0467 0.1104
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0033 0.0237
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0143 0.0402 0.095
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0022 0.0036 0.0084
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Echinococcus granulosus GPCR family 2 0.0096 0.0257 0.0609
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0148 0.0417 0.118
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis neuropeptide receptor 0.0165 0.0467 0.0467
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0068 0.0739
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.1104
Echinococcus multilocularis serotonin receptor 0.0165 0.0467 0.0467
Plasmodium falciparum phosphodiesterase delta, putative 0.0143 0.0402 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0165 0.0467 0.1104
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0034 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0014 0.0088
Leishmania major hypothetical protein, conserved 0.0025 0.0046 0.0492
Loa Loa (eye worm) hypothetical protein 0.0059 0.0149 0.034
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0143 0.0402 0.4556
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0068 0.7663
Schistosoma mansoni hypothetical protein 0.0449 0.1321 0.3028
Echinococcus granulosus axis inhibition protein axin 0.0237 0.0682 0.1614
Brugia malayi Protein kinase domain containing protein 0.0028 0.0054 0.0123
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0029 0.0067
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0241 0.0696 0.7929
Schistosoma mansoni protein kinase 0.0025 0.0045 0.0104
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica ARF GTPase activating protein, putative 0.0022 0.0036 0.0415
Brugia malayi PXA domain containing protein 0.0237 0.0682 0.1563
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0068 0.1238
Brugia malayi AKH receptor 0.0165 0.0467 0.1069
Echinococcus granulosus Regulator of G protein signaling 20 0.0237 0.0682 0.1614
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0054 0.0124
Onchocerca volvulus 0.0013 0.0008 0.0059
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0131 0.0299
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0106
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0014 0.0125
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.001 0 0.0002
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) PDE1B protein 0.0143 0.0402 0.092
Echinococcus multilocularis neuropeptide receptor A26 0.0165 0.0467 0.0467
Echinococcus multilocularis pdz domain containing protein 0.0022 0.0036 0.0036
Leishmania major cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0022 0.0036 0.0081
Brugia malayi ORL1-like opioid receptor 0.0165 0.0467 0.1069
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.015 0.015
Echinococcus granulosus alpha 1A adrenergic receptor 0.0165 0.0467 0.1104
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0165 0.0467 0.107
Echinococcus multilocularis neuropeptide receptor 0.0165 0.0467 0.0467
Schistosoma mansoni zinc finger protein 0.001 0 0.0001
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0122 0.2479
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Cadps2 protein 0.0022 0.0036 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus calcium activated potassium channel 0.0011 0.0004 0.0009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0078 0.0564
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0034 0.0034
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0078 0.0564
Schistosoma mansoni patched 1 0.009 0.0241 0.0552
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0739
Brugia malayi Galactosyltransferase family protein 0.0048 0.0116 0.0265
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Echinococcus multilocularis protein dispatched 1 0.0103 0.0279 0.0279
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0034 0.0034
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus granulosus tm gpcr rhodopsin 0.0165 0.0467 0.1104
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0009
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0165 0.0467 0.0467
Echinococcus granulosus death domain containing protein 0.0032 0.0066 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) melatonin receptor type 1A 0.0165 0.0467 0.1069
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0034 0.0246
Loa Loa (eye worm) hypothetical protein 0.0209 0.06 0.1376
Schistosoma mansoni goodpasture antigen-binding protein 0.0022 0.0036 0.0081
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Trichomonas vaginalis alpha chimerin, putative 0.0022 0.0036 0.0257
Echinococcus multilocularis protein patched 0.009 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0257 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0036 0.0884
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0068 0.1238
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis neuropeptide Y receptor 0.0165 0.0467 0.0467
Brugia malayi PXA domain containing protein 0.0237 0.0682 0.1563
Brugia malayi G-protein coupled receptor 0.0165 0.0467 0.1069
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0006 0.0014
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0883 0.2625 0.2625
Echinococcus multilocularis rac serine:threonine kinase 0.0028 0.0054 0.0054
Plasmodium vivax importin-beta 2, putative 0.0032 0.0067 0.168
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0042 0.0099
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0143 0.0402 0.0402
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0214 0.0615 0.8939
Brugia malayi TAR-binding protein 0.0062 0.0155 0.0355
Echinococcus granulosus neuropeptides capa receptor 0.0165 0.0467 0.1104
Brugia malayi Thioredoxin reductase 0.0094 0.0253 0.0579
Trichomonas vaginalis centaurin alpha, putative 0.0022 0.0036 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0142 0.0142
Schistosoma mansoni cellular tumor antigen P53 0.005 0.012 0.0275
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0034 0.0078
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0028 0.0054 0.0578
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0034 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0084 0.1106
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0165 0.0467 0.0467
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.029 0.0665

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 7.7 nM Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 25221662
Emax (functional) = 142.6 % Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay relative to untreated control ChEMBL. 25221662
Ki (binding) = 1.8 nM Displacement of [3H]Ile5,6deltorphin II from delta opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assay ChEMBL. 25221662

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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