Detailed information for compound 28141

Basic information

Technical information
  • TDR Targets ID: 28141
  • Name: N,N'-bis(naphthalen-1-ylmethyl)butane-1,4-dia mine
  • MW: 368.514 | Formula: C26H28N2
  • H donors: 2 H acceptors: 0 LogP: 5.57 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: C(NCc1cccc2c1cccc2)CCCNCc1cccc2c1cccc2
  • InChi: 1S/C26H28N2/c1-3-15-25-21(9-1)11-7-13-23(25)19-27-17-5-6-18-28-20-24-14-8-12-22-10-2-4-16-26(22)24/h1-4,7-16,27-28H,5-6,17-20H2
  • InChiKey: HUTFIRDOUMNKCG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N,N'-bis(1-naphthylmethyl)butane-1,4-diamine
  • N,N'-bis(1-naphthalenylmethyl)butane-1,4-diamine
  • 1-naphthylmethyl-[4-(1-naphthylmethylamino)butyl]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0055 0.008
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0009 0.0016
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0037 0.0195
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0024 0.0116
Schistosoma mansoni coup transcription factor 0.0022 0.004 0.0078
Schistosoma mansoni zinc finger protein 0.0021 0.0037 0.0074
Onchocerca volvulus 0.0199 0.0583 0.1116
Schistosoma mansoni inositol monophosphatase 0.0122 0.0347 0.0689
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0118 0.0218
Echinococcus multilocularis protein C ets 2 0.001 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.0016 0.0024 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.004 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.004 0.0073
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0004 0.0008
Echinococcus granulosus 6 phosphofructokinase 0.0127 0.0362 0.0668
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Schistosoma mansoni hypothetical protein 0.0313 0.0932 0.1848
Brugia malayi Cytochrome P450 family protein 0.0021 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0009 0.0009
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0037 0.0195
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0199 0.0583 0.1116
Onchocerca volvulus 0.0057 0.0149 0.0278
Brugia malayi hypothetical protein 0.061 0.1839 0.2688
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.122
Schistosoma mansoni ets-related 0.001 0.0005 0.001
Echinococcus granulosus single minded 2 0.0045 0.0112 0.0207
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0199 0.0583 0.0852
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.035 0.2153
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) glutathione reductase 0.0047 0.0118 0.0173
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Schistosoma mansoni transient receptor potential channel 0.01 0.0279 0.0553
Schistosoma mansoni neurotransmitter gated ion channel 0.0026 0.0055 0.0108
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0118 0.0165
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0024 0.0116
Schistosoma mansoni hypothetical protein 0.0145 0.0417 0.0827
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0029 0.0029
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0046 0.0085
Entamoeba histolytica hypothetical protein 0.0031 0.0068 0.0392
Onchocerca volvulus 0.0029 0.0061 0.0109
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0014 0.0053
Plasmodium vivax adenosine deaminase, putative 0.0534 0.1607 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0025 0.0037
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0069
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0012 0.0024
Mycobacterium tuberculosis Conserved protein 0.0041 0.01 0.0593
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0012 0.0009 0.0009
Onchocerca volvulus 0.0199 0.0583 0.1116
Echinococcus granulosus intermediate filament protein 0.0027 0.0057 0.0105
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0122 0.0347 0.2139
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0013 0.0012 0.0012
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0037 0.0045
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0018 0.0019
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0068 0.0099
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni adenosine deaminase 0.0534 0.1607 0.3185
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0026 0.0051
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0005 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.004 0.0058
Leishmania major hypothetical protein, conserved 0.0016 0.0024 0.0027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.021 0.0298
Echinococcus multilocularis adenosine deaminase 0.0534 0.1607 0.1607
Entamoeba histolytica protein kinase rad3, putative 0.001 0.0006 0.0003
Brugia malayi G protein-coupled receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Schistosoma mansoni hypothetical protein 0.0021 0.0037 0.0072
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0037
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0123 0.035 0.0504
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0024 0.0044
Mycobacterium ulcerans adenosine deaminase 0.0534 0.1607 1
Brugia malayi putative neuropeptide receptor 0.0199 0.0583 0.0852
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0057 0.0149 0.0275
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0009 0.0017
Brugia malayi Dopamine receptor protein 1 0.0199 0.0583 0.0852
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0139 0.0397 0.0788
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0013 0.0013 0.0092
Echinococcus multilocularis g protein coupled receptor 0.0199 0.0583 0.0583
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0009 0.0009
Brugia malayi cytochrome P450 0.0021 0.0037 0.0053
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0024 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Loa Loa (eye worm) norepinephrine transporter 0.1658 0.5045 0.7372
Onchocerca volvulus 0.0281 0.0835 0.1601
Plasmodium falciparum amino acid transporter, putative 0.0281 0.0835 0.518
Schistosoma mansoni synaptojanin 0.0016 0.0024 0.0047
Brugia malayi Serotonin receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0064 0.008
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0026
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0057 0.0149 0.0149
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.004 0.0058
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0057 0.0149 0.0275
Schistosoma mansoni hypothetical protein 0.002 0.0035 0.007
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0024 0.0116
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0057 0.0149 0.0218
Brugia malayi Cation transporter family protein 0.0057 0.0149 0.0218
Leishmania major hypothetical protein, conserved 0.0013 0.0012 0.001
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.01 0.0593
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0026
Schistosoma mansoni hypothetical protein 0.0199 0.0583 0.1156
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0113 0.0113
Loa Loa (eye worm) histone methyltransferase 0.001 0.0004 0.0006
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0304 0.1863
Onchocerca volvulus 0.0199 0.0583 0.1116
Leishmania major hypothetical protein, conserved 0.0174 0.0506 0.0732
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Brugia malayi hypothetical protein 0.0026 0.0055 0.008
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0362 0.2228
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0157 0.029
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0025 0.0039
Schistosoma mansoni neurotransmitter gated ion channel 0.0026 0.0055 0.0108
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0174 0.0506 0.0732
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.01 0.0593
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0009 0.0018
Echinococcus granulosus sex peptide receptor 0.0199 0.0583 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0199 0.0583 0.0583
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0068 0.0091
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0122 0.0347 0.2137
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.01 0.0593
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0037 0.0053
Onchocerca volvulus 0.0031 0.0068 0.0122
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0281 0.0835 0.0835
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Echinococcus granulosus synaptojanin 1 0.0016 0.0024 0.0044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.003 0.0044
Brugia malayi RE15519p 0.0199 0.0583 0.0852
Echinococcus granulosus zinc finger protein 0.0021 0.0037 0.0069
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2246 0.6843 1
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0442 0.0442
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0005 0.0009
Onchocerca volvulus 0.0199 0.0583 0.1116
Echinococcus granulosus microtubule associated protein 2 0.1531 0.4655 0.8587
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0281 0.0835 0.122
Brugia malayi Cyclic-nucleotide gated cation channel 0.0012 0.0009 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0021 0.0039
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0057 0.0149 0.0218
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.004 0.0058
Loa Loa (eye worm) DR-78 0.001 0.0005 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0468 0.1405 0.2053
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0049 0.0272
Loa Loa (eye worm) hypothetical protein 0.0069 0.0185 0.027
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.003 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0012 0.0009 0.0017
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0024 0.0047
Schistosoma mansoni cpg binding protein 0.0029 0.0061 0.0121
Brugia malayi Nuclear hormone receptor E75 0.001 0.0005 0.0007
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0035 0.0052
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0123 0.0244
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.021 0.0415
Echinococcus multilocularis g protein coupled receptor 0.0199 0.0583 0.0583
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Echinococcus granulosus inositol monophosphatase 0.0013 0.0013 0.0024
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0024 0.012
Loa Loa (eye worm) hypothetical protein 0.036 0.1075 0.1571
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0026 0.0055 0.008
Schistosoma mansoni rab6-interacting 0.0044 0.0108 0.0214
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0362 0.2228
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0024 0.0119
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0281 0.0835 0.0835
Echinococcus multilocularis orexin receptor type 2 0.0199 0.0583 0.0583
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0004 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.004 0.004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.021 0.0306
Brugia malayi neuropeptide F receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0042
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0068 0.0091
Treponema pallidum NADH oxidase 0.0016 0.0024 0.0000090952
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0122 0.0347 0.2099
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0026 0.0055 0.0101
Plasmodium vivax telomerase reverse transcriptase, putative 0.0466 0.1398 0.8693
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.035 0.2153
Echinococcus multilocularis glycine receptor subunit beta 0.0057 0.0149 0.0149
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.035 0.0694
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0174 0.0506 0.0732
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0005 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0081 0.0222 0.0394
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0039
Loa Loa (eye worm) hypothetical protein 0.0313 0.0932 0.1362
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0064 0.0369
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0046 0.0091
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0144 0.0144
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0199 0.0583 0.1156
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0116 0.0229
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0199 0.0583 0.1156
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0081 0.0222 0.6115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0024 0.0024
Loa Loa (eye worm) multidrug resistance protein 3 0.001 0.0005 0.0008
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0093 0.0135
Mycobacterium tuberculosis Conserved protein 0.0041 0.01 0.0593
Brugia malayi Ets-domain containing protein 0.007 0.0189 0.0276
Brugia malayi transcription factor E74 isoform 0.001 0.0005 0.0007
Brugia malayi Melatonin receptor type 1A 0.0199 0.0583 0.0852
Schistosoma mansoni acetylcholine receptor-related 0.0026 0.0055 0.0108
Brugia malayi GnHR receptor homolog 0.0199 0.0583 0.0852
Schistosoma mansoni amine GPCR 0.0199 0.0583 0.1156
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0304 0.1863
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0025 0.005
Plasmodium vivax hypothetical protein, conserved 0.0041 0.01 0.0593
Brugia malayi Inositol monophosphatase family protein 0.0013 0.0013 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0199 0.0583 0.1076
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0013 0.0014 0.0028
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0057 0.0149 0.0275
Onchocerca volvulus Neuropeptide F receptor homolog 0.0199 0.0583 0.1116
Echinococcus multilocularis short transient receptor potential channel 6 0.0067 0.0179 0.0179
Schistosoma mansoni hypothetical protein 0.0017 0.0025 0.005
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0026 0.0055 0.008
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0122 0.0347 1
Brugia malayi Cation transporter family protein 0.0057 0.0149 0.0218
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.003 0.0056
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0064 0.0369
Brugia malayi G protein-coupled receptor F59B2.13 0.0199 0.0583 0.0852
Echinococcus granulosus glycine receptor subunit alpha 1 0.0057 0.0149 0.0275
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0199 0.0583 0.1156
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.003 0.0044
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0022 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.006 0.011
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0029 0.0035
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0009 0.0018
Mycobacterium tuberculosis Monophosphatase CysQ 0.0013 0.0013 0.0048
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.003 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Echinococcus granulosus tar DNA binding protein 0.0072 0.0193 0.0355
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0019
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0031 0.0036
Schistosoma mansoni smdr2 0.001 0.0005 0.001
Brugia malayi nuclear hormone receptor 0.001 0.0005 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.1531 0.4655 0.4655
Mycobacterium ulcerans beta-lactamase 0.0041 0.01 0.0547
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1781 0.542 0.542
Onchocerca volvulus 0.0199 0.0583 0.1116
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.004 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0199 0.0583 0.0583
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Schistosoma mansoni hypothetical protein 0.0012 0.0012 0.0023
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0052 0.0102
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.003 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0362 0.2228
Brugia malayi nuclear hormone receptor 0.0022 0.004 0.0058
Echinococcus granulosus inositol monophosphatase 1 0.0122 0.0347 0.0641
Treponema pallidum adenosine deaminase 0.0534 0.1607 0.3153
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0024 0.0035
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0885 0.268 0.3917
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0068 0.0135
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.001 0.0005 0.0003
Echinococcus multilocularis fmrfamide receptor 0.0199 0.0583 0.0583
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0018 0.0081
Onchocerca volvulus 0.0016 0.0024 0.0037
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0362 0.0529
Echinococcus multilocularis fmrfamide receptor 0.0199 0.0583 0.0583
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1658 0.5045 0.7372
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0009 0.0017
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0029 0.0043
Brugia malayi G-protein coupled receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0024 0.012
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0024 0.0021
Brugia malayi hypothetical protein 0.0044 0.0108 0.0157
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0362 0.0718
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0026 0.0055 0.0055
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0081 0.0222 0.131
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.003 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0029 0.0153
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.0012 0.0053
Echinococcus multilocularis muscleblind protein 0.0153 0.0442 0.0442
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0046 0.0113 0.0166
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0005 0.0009
Brugia malayi beta-lactamase 0.0041 0.01 0.0146
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0024 0.0116
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0026
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0127 0.0362 0.0674
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.001 0.0005 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Loa Loa (eye worm) hypothetical protein 0.0037 0.0088 0.0129
Schistosoma mansoni sodium/chloride dependent transporter 0.1658 0.5045 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Brugia malayi hypothetical protein 0.001 0.0005 0.0007
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0057 0.0149 0.0218
Onchocerca volvulus 0.0057 0.0149 0.0278
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0174 0.0506 0.0731
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0026 0.0055 0.008
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0057 0.0149 0.0295
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0005 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0065 0.0129
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0081 0.0222 0.0316
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.004 0.0058
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0025 0.0046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0193 0.0281
Schistosoma mansoni gabp alpha 0.007 0.0189 0.0375
Trichomonas vaginalis adenosine deaminase, putative 0.0534 0.1607 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0057 0.0083
Schistosoma mansoni vesicular acetylcholine transporter 0.0885 0.268 0.5313
Echinococcus multilocularis sodium and chloride dependent glycine 0.0281 0.0835 0.0835
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.021 0.0298
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Echinococcus granulosus glycine receptor subunit beta 0.0057 0.0149 0.0275
Brugia malayi intermediate filament protein 0.0027 0.0057 0.0083
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0005 0.0005
Loa Loa (eye worm) acetylcholine receptor protein 0.0026 0.0055 0.008
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0193 0.0382
Echinococcus granulosus glycine receptor subunit alpha 1 0.0057 0.0149 0.0275
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0005 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0026
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0174 0.0506 0.0726
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0144 0.0144
Mycobacterium tuberculosis Probable monophosphatase 0.0013 0.0013 0.0048
Schistosoma mansoni nuclear receptor 0.001 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0019
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.0734 0.0734
Echinococcus multilocularis multidrug resistance protein 1 0.001 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0037 0.0195
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0193 0.0281
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.0781 0.4846
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.1705 0.5186 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Loa Loa (eye worm) ACC-1 protein 0.0057 0.0149 0.0218
Schistosoma mansoni neuropeptide f receptor 76f 0.0199 0.0583 0.1156
Brugia malayi 6-phosphofructokinase 0.0127 0.0362 0.0529
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0209 0.0613 0.0613
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0005 0.001
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0281 0.0835 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0123 0.035 0.0504
Giardia lamblia GTOR 0.0019 0.003 0.0185
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0018 0.0027
Entamoeba histolytica adenosine deaminase, putative 0.0534 0.1607 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0005 0.0007
Schistosoma mansoni microtubule-associated protein tau 0.1531 0.4655 0.9227
Onchocerca volvulus 0.0041 0.01 0.0184
Trypanosoma cruzi AMP deaminase, putative 0.0174 0.0506 0.0731
Echinococcus granulosus tyrosine protein kinase Lyn 0.0009 0.0001 0.0002
Schistosoma mansoni transient receptor potential channel 4 0.01 0.0279 0.0553
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0529 0.0975
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.004 0.0058
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0037 0.004
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0024 0.0026
Echinococcus granulosus neuropeptide receptor 0.0351 0.1047 0.1932
Onchocerca volvulus 0.0041 0.01 0.0184
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.004 0.0067
Echinococcus multilocularis nAChR subunit 0.0031 0.0068 0.0068
Echinococcus multilocularis musashi 0.0027 0.0057 0.0057
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0199 0.0583 0.0583
Echinococcus granulosus vesicular acetylcholine transporter 0.0885 0.268 0.4945
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0014 0.0026
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.01 0.0593
Giardia lamblia Hypothetical protein 0.0013 0.0013 0.0059
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.003 0.0157
Schistosoma mansoni sodium/chloride dependent transporter 0.0283 0.0838 0.1661
Onchocerca volvulus 0.0139 0.0397 0.0758
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0144 0.0266
Loa Loa (eye worm) RNA binding protein 0.0072 0.0193 0.0281
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0122 0.0347 0.2137
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.01 0.0138
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0024 0.0026
Onchocerca volvulus 0.0031 0.0068 0.0122
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0055 0.008
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0005 0.0005
Brugia malayi Doublecortin family protein 0.0044 0.0108 0.0157
Loa Loa (eye worm) ACC-1 protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0008
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0024 0.0044
Mycobacterium ulcerans putative regulatory protein 0.0041 0.01 0.0547
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.0734 0.1355
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0005 0.0005
Brugia malayi Dopamine receptor protein 2 0.0199 0.0583 0.0852
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0021 0.0021
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0009 0.0009
Echinococcus granulosus lamin dm0 0.0027 0.0057 0.0105
Onchocerca volvulus 0.0027 0.0057 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi MH2 domain containing protein 0.0126 0.0359 0.0524
Schistosoma mansoni loxhd1 0.0044 0.0108 0.0214
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0005 0.0005
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0024 0.0027
Echinococcus multilocularis sodium and chloride dependent glycine 0.0281 0.0835 0.0835
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0024 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0199 0.0583 0.1156
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0534 0.1607 1
Onchocerca volvulus 0.0051 0.0129 0.0239
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0037 0.0195
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0189 0.0276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0057 0.0149 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Loa Loa (eye worm) cytochrome P450 0.0021 0.0037 0.0053
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0057 0.0149 0.0218
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0013 0.0013 0.0005
Echinococcus multilocularis neuropeptide receptor A26 0.0199 0.0583 0.0583
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.003 0.0031
Brugia malayi Cytochrome P450 family protein 0.0021 0.0037 0.0053
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0199 0.0583 0.0852
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.01 0.0138
Toxoplasma gondii hypothetical protein 0.0281 0.0835 0.518
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0037 0.0195
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0014
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0029 0.0058
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0031 0.0068 0.01
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0189 0.0349
Schistosoma mansoni transient receptor potential channel 0.0067 0.0179 0.0355
Loa Loa (eye worm) hypothetical protein 0.2246 0.6843 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0052 0.0075
Brugia malayi putative neuropeptide receptor NPR1 0.0199 0.0583 0.0852
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.01 0.0146
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0108 0.0199
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0021 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.004 0.004
Echinococcus multilocularis 6 phosphofructokinase 0.0127 0.0362 0.0362
Brugia malayi hypothetical protein 0.0026 0.0055 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.021 0.0306
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.0012 0.0046
Leishmania major hypothetical protein, conserved 0.0029 0.0064 0.0086
Loa Loa (eye worm) G-protein coupled receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.004 0.0058
Echinococcus multilocularis g protein coupled receptor 0.0199 0.0583 0.0583
Schistosoma mansoni lipoxygenase 0.0196 0.0573 0.1136
Schistosoma mansoni pap-inositol-14-phosphatase 0.0013 0.0013 0.0026
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0009 0.0025
Brugia malayi Pre-SET motif family protein 0.0204 0.0597 0.0873
Onchocerca volvulus 0.0057 0.0149 0.0278
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0112 0.0317 0.0463
Schistosoma mansoni single-minded 0.0056 0.0145 0.0287
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi Pre-SET motif family protein 0.003 0.0065 0.0095
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0005 0.001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Schistosoma mansoni survival motor neuron protein 0.0051 0.0129 0.0256
Loa Loa (eye worm) hypothetical protein 0.0029 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0039 0.0093 0.0135
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.004 0.0095 0.0139
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.034 0.2055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0052 0.0289
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.0018 0.0156
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0024 0.0119
Entamoeba histolytica adenosine deaminase, putative 0.0534 0.1607 1
Echinococcus granulosus FTZ F1 alpha 0.0022 0.004 0.0073
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0209 0.0613 0.1131
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0049
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0597 0.0873
Loa Loa (eye worm) hypothetical protein 0.004 0.0096 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0018 0.0018
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.122
Echinococcus granulosus transient receptor potential gamma protein 0.01 0.0279 0.0515
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0052 0.0293
Trypanosoma cruzi AMP deaminase, putative 0.0174 0.0506 0.0731
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0009 0.0014
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0005 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.01 0.0593
Brugia malayi hypothetical protein 0.0249 0.0734 0.1073
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0193 0.0382
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0021 0.0039
Schistosoma mansoni intermediate filament proteins 0.0027 0.0057 0.0113
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.01 0.0593
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0018 0.0081
Leishmania major hypothetical protein, conserved 0.0016 0.0024 0.0027
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0037 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0037 0.0195
Plasmodium vivax SET domain protein, putative 0.003 0.0065 0.0372
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.005 0.0125 0.0248
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0529 0.0529
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi beta-lactamase family protein 0.0041 0.01 0.0146
Echinococcus multilocularis neuropeptide Y receptor 0.0199 0.0583 0.0583
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.003 0.0044
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0123 0.0229
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0027 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0534 0.1607 1
Trypanosoma brucei AMP deaminase, putative 0.0174 0.0506 0.0726
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2246 0.6843 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Echinococcus granulosus RUN 0.0044 0.0108 0.0199
Leishmania major telomerase reverse transcriptase, putative 0.0466 0.1398 0.2036
Schistosoma mansoni neuropeptide receptor 0.0199 0.0583 0.1156
Brugia malayi bHLH-PAS transcription factor 0.0041 0.01 0.0146
Schistosoma mansoni hypothetical protein 0.1589 0.4832 0.9579
Trypanosoma cruzi AMP deaminase 2, putative 0.0174 0.0506 0.0731
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0052 0.0095
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0108 0.0108
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0046 0.0113 0.0166
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0193 0.0193
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0013 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0018
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus multilocularis dro:myosuppressin receptor 0.0199 0.0583 0.0583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0199 0.0583 0.0583
Brugia malayi Cytochrome P450 family protein 0.0031 0.0068 0.0099
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0029 0.0029
Brugia malayi Bromodomain containing protein 0.0037 0.0088 0.0129
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0024 0.0224
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0123 0.035 0.0504
Schistosoma mansoni neuropeptide receptor 0.0199 0.0583 0.1156
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0037 0.0148
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0199 0.0583 0.1076
Echinococcus granulosus G protein coupled receptor 139 0.0199 0.0583 0.1076
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.034 0.2093
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0529 0.1048
Schistosoma mansoni neuropeptide receptor 0.0351 0.1047 0.2076
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0024 0.0116
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0009 0.0018
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0095 0.0559
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0118 0.0118
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0057 0.0149 0.0218
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0024 0.0116
Echinococcus multilocularis neuropeptides capa receptor 0.0199 0.0583 0.0583
Toxoplasma gondii ABC1 family protein 0.0041 0.01 0.0596
Brugia malayi nuclear receptor NHR-88 0.001 0.0005 0.0007
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0024 0.0027
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0012
Schistosoma mansoni synaptojanin 0.0016 0.0024 0.0047
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0144 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.0012 0.0018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0199 0.0583 0.0583
Brugia malayi Uncoordinated protein 44 0.0017 0.0025 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.0016 0.0021 0.0031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0199 0.0583 0.0852
Toxoplasma gondii exonuclease III APE 0.0081 0.0222 0.1355
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.004 0.0073
Schistosoma mansoni sodium-dependent amino acid transporter 0.0281 0.0835 0.1654
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0024 0.0024
Brugia malayi sulfakinin receptor protein 0.0199 0.0583 0.0852
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0057 0.0083
Loa Loa (eye worm) hypoxia-induced factor 1 0.0173 0.0502 0.0734
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0037 0.0046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.122
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0466 0.1398 0.2036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.002
Brugia malayi RNA binding protein 0.0072 0.0193 0.0281
Loa Loa (eye worm) melatonin receptor type 1A 0.0199 0.0583 0.0852
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.003 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0024 0.0027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0079 0.0461
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0005 0.0005
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0005 0.001
Brugia malayi Serotonin receptor 0.0199 0.0583 0.0852
Brugia malayi mbt repeat family protein 0.0049 0.0123 0.018
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.0174 0.0506 0.0739
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0024 0.0021
Schistosoma mansoni opsin-like receptor 0.0199 0.0583 0.1156
Schistosoma mansoni hypothetical protein 0.0407 0.1218 0.2414
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Echinococcus granulosus mitogen activated protein kinase 0.0123 0.035 0.0646
Echinococcus granulosus allatostatin A receptor 0.0199 0.0583 0.1076
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0057 0.0149 0.0149
Brugia malayi TAR-binding protein 0.0072 0.0193 0.0281
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0018 0.0081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0024 0.0026
Schistosoma mansoni adenosine deaminase-related 0.0534 0.1607 0.3185
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.001 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Loa Loa (eye worm) RecQ helicase 0.0025 0.0049 0.0071
Onchocerca volvulus 0.0026 0.0055 0.0096
Loa Loa (eye worm) hypothetical protein 0.1148 0.3485 0.5092
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0024 0.0116
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.01 0.0593
Brugia malayi hypothetical protein 0.001 0.0005 0.0007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0199 0.0583 0.1156
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.001 0.0006 0.0006
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0052 0.0052
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.0261 0.0481
Schistosoma mansoni lamin 0.0027 0.0057 0.0113
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0129 0.0188
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.021 0.0299
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0025 0.0046
Brugia malayi Ets-domain containing protein 0.001 0.0005 0.0007
Echinococcus multilocularis lamin 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus glycine receptor subunit alpha 1 0.0057 0.0149 0.0275
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.036 0.1075 0.1571
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0122 0.0347 0.05
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.004 0.0078
Brugia malayi Abnormal catecholamine distribution protein 1 0.0217 0.0638 0.0932
Brugia malayi Inositol-1 0.0122 0.0347 0.0508
Treponema pallidum sodium- and chloride- dependent transporter 0.1658 0.5045 1
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0174 0.0506 0.0732
Echinococcus granulosus serotonin receptor 0.0199 0.0583 0.1076
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0026 0.0055 0.008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.004 0.0058
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.003 0.0031
Echinococcus granulosus sodium and chloride dependent glycine 0.0281 0.0835 0.154
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0035
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.001 0.0006 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0057 0.0149 0.0149
Plasmodium vivax glutathione reductase, putative 0.0047 0.0118 0.0706
Giardia lamblia Kinase, CMGC MAPK 0.0123 0.035 0.248
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0064 0.0366
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0123 0.0123
Trypanosoma brucei AMP deaminase, putative 0.0174 0.0506 0.0726
Echinococcus multilocularis serotonin receptor 0.0199 0.0583 0.0583
Brugia malayi hypothetical protein 0.0044 0.0108 0.0157
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0013 0.0013 0.0013
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0024 0.0138
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0145 0.0417 0.061
Trichomonas vaginalis inositol monophosphatase, putative 0.0013 0.0013 0.0048
Echinococcus granulosus cpg binding protein 0.0032 0.0072 0.0132
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0123 0.035 0.0504
Brugia malayi neuropeptide F receptor 0.0199 0.0583 0.0852
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0196 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Toxoplasma gondii AMP deaminase 0.0174 0.0506 0.3127
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0081 0.0222 0.1558
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0199 0.0583 0.1076
Echinococcus multilocularis inositol monophosphatase 1 0.0122 0.0347 0.0347
Brugia malayi Cytochrome P450 family protein 0.0031 0.0068 0.0099
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0304 0.1863
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0013 0.0013 0.0005
Echinococcus multilocularis transient receptor potential gamma protein 0.01 0.0279 0.0279
Echinococcus multilocularis short transient receptor potential channel 6 0.0067 0.0179 0.0179
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0144 0.021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0199 0.0583 0.1156
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0108 0.0108
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0025 0.0046
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0057 0.0149 0.0218
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.004 0.0067
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0005 0.0009
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0029 0.015
Schistosoma mansoni cript-related 0.0016 0.0024 0.0047
Echinococcus multilocularis serotonin receptor 0.0199 0.0583 0.0583
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0127 0.0362 0.2228
Loa Loa (eye worm) hypothetical protein 0.0044 0.0108 0.0157
Brugia malayi hypothetical protein 0.0281 0.0835 0.122
Loa Loa (eye worm) hypothetical protein 0.0187 0.0547 0.0799
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.01 0.0547
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi Adenosine/AMP deaminase family protein 0.0534 0.1607 0.2348
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0362 0.2228
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0005 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.004 0.0058
Plasmodium vivax hypothetical protein, conserved 0.0281 0.0835 0.5178
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.003 0.0037
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0057 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.1981 0.6031 0.8813
Schistosoma mansoni zinc finger protein 0.001 0.0005 0.001
Brugia malayi steroid hormone receptor 0.0022 0.004 0.0058
Brugia malayi follicle stimulating hormone receptor 0.0468 0.1405 0.2053
Plasmodium falciparum glutathione reductase 0.0047 0.0118 0.0709
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0021
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0249 0.0734 0.1073
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0037 0.0148
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0005 0.0007
Echinococcus multilocularis serotonin transporter 0.1658 0.5045 0.5045
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.021 0.021
Echinococcus multilocularis inositol monophosphatase 0.0013 0.0013 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.004 0.0058
Trypanosoma brucei protein kinase, putative 0.0123 0.035 0.0499
Schistosoma mansoni amine GPCR 0.0199 0.0583 0.1156
Mycobacterium tuberculosis Probable reductase 0.0108 0.0304 0.1863
Echinococcus granulosus neuropeptide FF receptor 2 0.0199 0.0583 0.1076
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0057 0.0149 0.0218
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0113 0.0209
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0095 0.0559
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0024 0.0027
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0014 0.0053
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0018 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.0199 0.0583 0.1076
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0005 0.001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0118 0.0706
Trypanosoma cruzi AMP deaminase, putative 0.0174 0.0506 0.0731
Brugia malayi latrophilin 2 splice variant baaae 0.0313 0.0932 0.1362
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0057 0.0149 0.0275
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0037 0.0148
Loa Loa (eye worm) hypothetical protein 0.0044 0.0108 0.0157
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0193 0.0382
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.003 0.0036
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0181 0.0529 0.0773
Echinococcus granulosus death domain containing protein 0.0017 0.0025 0.0046
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0025 0.0025
Brugia malayi hypothetical protein 0.0019 0.0032 0.0047
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0024 0.012
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0024 0.0026
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0199 0.0583 0.1076
Echinococcus granulosus Ankyrin 0.0017 0.0026 0.0047
Loa Loa (eye worm) AMP deaminase 0.0174 0.0506 0.0739
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0031 0.0037
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) serotonin transporter b 0.1658 0.5045 0.7372
Onchocerca volvulus 0.0049 0.0123 0.0229
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0037 0.0148
Loa Loa (eye worm) hypothetical protein 0.036 0.1075 0.1571
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0012
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0057 0.0149 0.0149
Plasmodium falciparum thioredoxin reductase 0.0047 0.0118 0.0709
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0037 0.0195
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0193 0.0382
Echinococcus multilocularis G-protein coupled receptor, putative 0.0199 0.0583 0.0583
Loa Loa (eye worm) phosphofructokinase 0.0127 0.0362 0.0529
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.034 0.2093
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0005 0.0005
Plasmodium vivax amine transporter, putative 0.0281 0.0835 0.5178
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0281 0.0835 0.154
Loa Loa (eye worm) hypothetical protein 0.0056 0.0144 0.021
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0068 0.0135
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Schistosoma mansoni hypothetical protein 0.0199 0.0583 0.1156
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0012 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0065 0.0129
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0057 0.0149 0.0295
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0049 0.0049
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0024 0.0116
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0217 0.0638 0.0932
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0005 0.0007
Trypanosoma brucei telomerase reverse transcriptase 0.0466 0.1398 0.2031
Echinococcus multilocularis synaptojanin 1 0.0016 0.0024 0.0024
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.518
Echinococcus granulosus neuropeptides capa receptor 0.0199 0.0583 0.1076
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.004 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Echinococcus multilocularis somatostatin receptor 0.0199 0.0583 0.0583
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0068 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Echinococcus granulosus protein C ets 2 0.001 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0037 0.0148
Echinococcus multilocularis lamin dm0 0.0027 0.0057 0.0057
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0199 0.0583 0.1076
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0057 0.0149 0.0149
Leishmania major cytochrome p450-like protein 0.0031 0.0068 0.0091
Brugia malayi Inositol monophosphatase family protein 0.0013 0.0013 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0009 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.004 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus granulosus g-protein coupled receptor 0.0199 0.0583 0.1076
Onchocerca volvulus 0.0199 0.0583 0.1116
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0012 0.0009
Echinococcus granulosus synaptic vesicular amine transporter 0.0217 0.0638 0.1177
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0037 0.0195
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0529 0.1048
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0281 0.0835 0.154
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0024 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.01 0.0133
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0081 0.0222 0.0317
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0021
Onchocerca volvulus 0.0199 0.0583 0.1116
Loa Loa (eye worm) hypothetical protein 0.0139 0.0397 0.0581
Brugia malayi hypothetical protein 0.0011 0.0009 0.0012
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0123 0.035 0.0512
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Schistosoma mansoni polycystin 1-related 0.0044 0.0108 0.0214
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0081 0.0222 0.0222
Brugia malayi ORL1-like opioid receptor 0.0199 0.0583 0.0852
Onchocerca volvulus 0.0281 0.0835 0.1601
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0044
Echinococcus granulosus mitogen activated protein kinase 3 0.0123 0.035 0.0646
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0029 0.0043
Schistosoma mansoni hypothetical protein 0.0145 0.0417 0.0827
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.01 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.004 0.0078
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0061 0.0089
Echinococcus multilocularis mitogen activated protein kinase 0.0123 0.035 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus granulosus CTD small phosphatase protein like 0.0013 0.0012 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Brugia malayi glutathione reductase 0.0047 0.0118 0.0173
Giardia lamblia hypothetical protein 0.0016 0.0024 0.0137
Brugia malayi Cation transporter family protein 0.0139 0.0397 0.0581
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.0458 0.1376 0.2011
Brugia malayi Latrophilin receptor protein 2 0.0145 0.0417 0.061
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0199 0.0583 0.1156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0009 0.0012
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0123 0.0227
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.004 0.0218
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.004 0.0058
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0009 0.0014
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0145 0.0417 0.0417
Schistosoma mansoni DNA helicase recq5 0.001 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Echinococcus multilocularis 0.0013 0.0012 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Leishmania major cytochrome p450-like protein 0.0021 0.0037 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0081 0.0222 0.0316
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1658 0.5045 1
Schistosoma mansoni elf1 0.001 0.0005 0.001
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0362 0.0718
Echinococcus multilocularis geminin 0.1589 0.4832 0.4832
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0025 0.0037
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0057 0.0149 0.0295
Brugia malayi Thioredoxin reductase 0.0047 0.0118 0.0173
Echinococcus granulosus g protein coupled receptor 0.0199 0.0583 0.1076
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0029 0.0034
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.0012 0.0046
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0057 0.0149 0.0149
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0009 0.0017
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0026 0.0055 0.0055
Echinococcus multilocularis nAChR subunit 0.0057 0.0149 0.0149
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.004 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0064 0.0369
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Giardia lamblia Inositol 5-phosphatase 4 0.0016 0.0024 0.0137
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0021 0.0042
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0123 0.0227
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.004 0.004
Brugia malayi Telomerase reverse transcriptase 0.1239 0.3763 0.5498
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.004 0.0058
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0024 0.012
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0037 0.0195
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0362 0.0529
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0018 0.0027
Loa Loa (eye worm) fli-1 protein 0.0214 0.0628 0.0917
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.004 0.0073
Onchocerca volvulus 0.0015 0.0018 0.0026
Loa Loa (eye worm) TYRA-2 protein 0.0199 0.0583 0.0852
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0018
Schistosoma mansoni nAChR subunit 0.0026 0.0055 0.0108
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0009 0.0012
Schistosoma mansoni multidrug resistance protein 0.001 0.0005 0.001
Onchocerca volvulus 0.0199 0.0583 0.1116
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.518
Echinococcus granulosus orexin receptor type 2 0.0199 0.0583 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0009 0.0026
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0022 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0068 0.0099
Loa Loa (eye worm) LGC-31 protein 0.0057 0.0149 0.0218
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0145 0.0417 0.0417
Echinococcus multilocularis neuropeptide receptor 0.0351 0.1047 0.1047
Onchocerca volvulus 0.0041 0.01 0.0184
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0024 0.0116
Mycobacterium leprae putative cytochrome p450 0.0021 0.0037 0.0148
Entamoeba histolytica AMP deaminase, putative 0.0174 0.0506 0.3125
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0199 0.0583 0.0583
Echinococcus granulosus g protein coupled receptor 0.0199 0.0583 0.1076
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0037 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Mycobacterium ulcerans hypothetical protein 0.0041 0.01 0.0547
Echinococcus granulosus 7TM GPCR rhodopsin 0.0199 0.0583 0.1076
Trichomonas vaginalis set domain proteins, putative 0.0232 0.0683 0.4233
Schistosoma mansoni multidrug resistance protein 0.001 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0008
Mycobacterium leprae Probable lipase LipE 0.0041 0.01 0.0547
Loa Loa (eye worm) hypothetical protein 0.1658 0.5045 0.7372
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0139 0.0397 0.0581
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.003 0.0036
Onchocerca volvulus 0.0022 0.004 0.0067
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0199 0.0583 0.0583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Schistosoma mansoni ets 0.001 0.0005 0.001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.021 0.0387
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0014
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0079 0.0885
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0024 0.0116
Leishmania major cytochrome p450-like protein 0.0021 0.0037 0.0046
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0362 0.0516
Schistosoma mansoni transient receptor potential channel 0.0067 0.0179 0.0354
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.004 0.0078
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0529 0.0975
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0005 0.001
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0079 0.0461
Brugia malayi Bromodomain containing protein 0.0075 0.0203 0.0296
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Leishmania major AMP deaminase, putative 0.0174 0.0506 0.0732
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0281 0.0835 0.1654
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0013 0.0013 0.0016
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0108 0.0157
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0037 0.0148
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Echinococcus granulosus multidrug resistance protein 1 0.001 0.0005 0.001
Schistosoma mansoni nocturnin 0.0016 0.0024 0.0047
Brugia malayi conserved hypotetical protein 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0081
Onchocerca volvulus 0.0026 0.0055 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0024 0.0021
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0005 0.0005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0199 0.0583 0.0852
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0036
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0237 0.0437
Schistosoma mansoni nuclear hormone receptor 0.0022 0.004 0.0078
Plasmodium falciparum transporter, putative 0.0281 0.0835 0.518
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0037 0.0067
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0359 0.0524
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0458 0.1376 0.2011
Schistosoma mansoni neuropeptide receptor 0.0199 0.0583 0.1156
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0199 0.0583 0.0583
Loa Loa (eye worm) MBCTL1 0.0056 0.0144 0.021
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0362 0.0521
Echinococcus granulosus GPCR family 2 0.0145 0.0417 0.077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0199 0.0583 0.0583
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0055 0.008
Echinococcus granulosus neuropeptides capa receptor 0.0199 0.0583 0.1076
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0005 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0118 0.0173
Schistosoma mansoni opsin-like receptor 0.0199 0.0583 0.1156
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0024 0.0047
Echinococcus multilocularis neuropeptide receptor 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0153 0.0442 0.0646
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0005 0.0009
Schistosoma mansoni ets-related 0.0214 0.0628 0.1244
Schistosoma mansoni thyroid hormone receptor 0.0022 0.004 0.0078
Brugia malayi multidrug resistance protein 3 0.001 0.0005 0.0008
Toxoplasma gondii hypothetical protein 0.0013 0.0013 0.0051
Entamoeba histolytica AMP deaminase, putative 0.0174 0.0506 0.3125
Echinococcus granulosus alpha 1A adrenergic receptor 0.0199 0.0583 0.1076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0027
Schistosoma mansoni sodium/chloride dependent transporter 0.0281 0.0835 0.1654
Brugia malayi ecdysteroid receptor 0.0022 0.004 0.0058
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0116 0.0214
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) beta-lactamase 0.0041 0.01 0.0146
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0024 0.0021
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0005 0.0009
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0013 0.0012 0.0022
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0144 0.0266
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0024 0.012
Brugia malayi PAS domain containing protein 0.0056 0.0145 0.0211
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0108 0.0643
Leishmania major hypothetical protein, conserved 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.518
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Onchocerca volvulus 0.0044 0.0108 0.0199
Echinococcus granulosus 7tm_1 domain containing protein 0.0199 0.0583 0.1076
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0222 0.1352
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0037
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0534 0.1607 1
Brugia malayi nuclear receptor RXR 0.001 0.0005 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0011 0.0015
Echinococcus multilocularis allatostatin A receptor 0.0199 0.0583 0.0583
Schistosoma mansoni neuropeptide F-like receptor 0.0199 0.0583 0.1156
Toxoplasma gondii RNA-directed DNA polymerase 0.0466 0.1398 0.8694
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0065 0.0375
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Loa Loa (eye worm) hypothetical protein 0.01 0.0279 0.0408
Echinococcus granulosus nAChR subunit 0.0031 0.0068 0.0126
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0037 0.0148
Leishmania major protein kinase, putative 0.0016 0.0022 0.0024
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0037 0.0148
Echinococcus granulosus fmrfamide receptor 0.0199 0.0583 0.1076
Schistosoma mansoni AMP deaminase 0.0174 0.0506 0.1003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.004 0.004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Brugia malayi PHD-finger family protein 0.0026 0.0053 0.0078
Onchocerca volvulus Adenosine deaminase homolog 0.0534 0.1607 0.3092
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni amine GPCR 0.0199 0.0583 0.1156
Brugia malayi hypothetical protein 0.0026 0.0055 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0222 0.1352
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0024 0.0026
Schistosoma mansoni zinc finger protein 0.0015 0.0019 0.0039
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0029 0.0153
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0281 0.0835 0.154
Brugia malayi Ets-domain containing protein 0.007 0.0189 0.0276
Brugia malayi Dopamine receptor 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0081 0.0222 0.1352
Trypanosoma cruzi AMP deaminase, putative 0.0174 0.0506 0.0731
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0116 0.0229
Echinococcus multilocularis neuropeptide s receptor 0.0199 0.0583 0.0583
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0199 0.0583 0.0583
Schistosoma mansoni DNA helicase recq1 0.001 0.0005 0.0009
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0005 0.0009
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0079 0.0458
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0005 0.0005
Brugia malayi hypothetical protein 0.0011 0.0009 0.0012
Brugia malayi ABC transporter family protein 0.001 0.0005 0.0008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0458 0.1376 0.2011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.034 0.2093
Loa Loa (eye worm) hypothetical protein 0.0043 0.0106 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0037 0.0195
Echinococcus granulosus glycine receptor subunit beta 0.0057 0.0149 0.0275
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Onchocerca volvulus 0.0281 0.0835 0.1601
Schistosoma mansoni cpg binding protein 0.0032 0.0072 0.0142
Echinococcus multilocularis 0.0021 0.0037 0.0037
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0079 0.0461
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0199 0.0583 0.1156
Trypanosoma cruzi AMP deaminase, putative 0.0174 0.0506 0.0731
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0037 0.0148
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0199 0.0583 0.1076
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Trypanosoma brucei C-8 sterol isomerase, putative 0.2246 0.6843 1
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.035 0.2153
Echinococcus granulosus dnaJ subfamily B 0.0407 0.1218 0.2246
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.004 0.0073
Schistosoma mansoni hypothetical protein 0.0051 0.0129 0.0256
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.001 0.0005 0.001
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0024 0.0021
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0012 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0193 0.0382
Echinococcus granulosus muscleblind protein 0.0153 0.0442 0.0815
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0021 0.0042
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0049 0.0272
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0024 0.0116
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0093 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.004 0.0058
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0011 0.0015
Schistosoma mansoni inositol monophosphatase 0.0122 0.0347 0.0689
Echinococcus granulosus neuropeptide receptor 0.0199 0.0583 0.1076
Echinococcus multilocularis sex peptide receptor 0.0199 0.0583 0.0583
Echinococcus granulosus peptide allatostatin:somatostatin 0.0199 0.0583 0.1076
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0041 0.0051
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0199 0.0583 0.1156
Schistosoma mansoni lamin 0.0027 0.0057 0.0113
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.018
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0199 0.0583 0.1076
Echinococcus multilocularis neuropeptide Y receptor 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0199 0.0583 0.1156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0145 0.0417 0.077
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0005 0.0007
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0013 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.1981 0.6031 0.8813
Brugia malayi MAP kinase sur-1 0.0123 0.035 0.0512
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.001
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0037 0.0148
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0031 0.0068 0.0135
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0024 0.0035
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0109 0.0308 0.1892
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0029 0.0029
Echinococcus granulosus somatostatin receptor 0.0199 0.0583 0.1076
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0123 0.035 0.0504
Onchocerca volvulus 0.0016 0.0024 0.0037
Onchocerca volvulus 0.0199 0.0583 0.1116
Onchocerca volvulus 0.0199 0.0583 0.1116
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0189 0.0189
Loa Loa (eye worm) solute carrier family 6 member 4 0.1658 0.5045 0.7372
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0199 0.0583 0.1156
Plasmodium vivax adenosine/AMP deaminase, putative 0.0174 0.0506 0.3125
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0005 0.0009
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.003 0.016
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0037 0.0195
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0029 0.0153
Toxoplasma gondii hypothetical protein 0.0281 0.0835 0.518
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0024 0.0035
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.0012 0.0042
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0037 0.0195
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.003 0.0157
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0024 0.0027
Onchocerca volvulus 0.003 0.0065 0.0116
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0162 0.0322
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0057 0.0149 0.0218
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0012 0.0009 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.004 0.0058
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0009 0.0017
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0024 0.0026
Schistosoma mansoni 60S ribosomal protein L21 0.001 0.0004 0.0008
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0024 0.0035
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0037 0.0148
Mycobacterium ulcerans lipase LipD 0.0041 0.01 0.0547
Schistosoma mansoni hypothetical protein 0.0145 0.0417 0.0827
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0122 0.0347 0.05
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0026
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0005 0.001
Plasmodium falciparum telomerase reverse transcriptase 0.0466 0.1398 0.8694
Brugia malayi hypothetical protein 0.0187 0.0547 0.0799
Brugia malayi G-protein coupled receptor 0.0199 0.0583 0.0852
Onchocerca volvulus 0.0199 0.0583 0.1116
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Schistosoma mansoni nAChR subunit 0.0026 0.0055 0.0108
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0026 0.0055 0.008
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Brugia malayi nuclear receptor NHR-88 0.0022 0.004 0.0058
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0123 0.035 0.0499
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0068 0.01
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0024 0.0027
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0024 0.0119
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0079 0.0885
Schistosoma mansoni nuclear receptor 0.001 0.0005 0.001
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0049 0.0071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.004 0.0073
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.003 0.0056
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0052 0.0067
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0024 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0199 0.0583 0.1076
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0047
Echinococcus granulosus g protein coupled receptor 0.0199 0.0583 0.1076
Brugia malayi vesicular acetylcholine transporter unc-17 0.0885 0.268 0.3917
Schistosoma mansoni biogenic amine (5HT) receptor 0.0199 0.0583 0.1156
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0037 0.0195
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0057 0.0149 0.0218
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0037 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0037 0.0148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.01 0.0593
Echinococcus granulosus tm gpcr rhodopsin 0.1781 0.542 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0199 0.0583 0.1156
Echinococcus granulosus dro:myosuppressin receptor 0.0199 0.0583 0.1076
Giardia lamblia Telomerase catalytic subunit 0.0466 0.1398 1
Schistosoma mansoni opsin-like receptor 0.0199 0.0583 0.1156
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0026 0.0055 0.0055
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0042
Schistosoma mansoni cytochrome P450 0.0021 0.0037 0.0072
Brugia malayi Nuclear hormone receptor E75 0.001 0.0005 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0064 0.0085
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0304 0.1863
Echinococcus multilocularis g-protein coupled receptor 0.0199 0.0583 0.0583
Mycobacterium ulcerans 6-phosphofructokinase 0.0127 0.0362 0.219
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Loa Loa (eye worm) latrophilin receptor protein 2 0.0145 0.0417 0.061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0081 0.0222 0.0311
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0037
Schistosoma mansoni biogenic amine receptor 0.0199 0.0583 0.1156
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0029 0.0034
Trichomonas vaginalis esterase, putative 0.0041 0.01 0.0593
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0024 0.0069
Echinococcus multilocularis zinc finger protein 0.0021 0.0037 0.0037
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0009 0.0018
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0025 0.0025
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0024 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.004 0.0058
Schistosoma mansoni voltage-gated potassium channel 0.005 0.0125 0.0248
Onchocerca volvulus 0.0174 0.0506 0.0967
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0009 0.0012
Brugia malayi 6-phosphofructokinase 0.0127 0.0362 0.053
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.011 0.011
Plasmodium falciparum multidrug resistance protein 1 0.001 0.0005 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.0199 0.0583 0.1076
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0037 0.0148
Onchocerca volvulus 0.0199 0.0583 0.1116
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0037 0.0195
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0174 0.0506 0.0731
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0123 0.0244
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Echinococcus granulosus hypothetical protein 0.0199 0.0583 0.1076
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0024 0.0037
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0057 0.0149 0.0149
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0079 0.0461
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0181 0.0529 0.0773
Brugia malayi adenosine monophosphate deaminase 0.0174 0.0506 0.0739
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.122
Brugia malayi hypothetical protein 0.0026 0.0055 0.008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0199 0.0583 0.0583
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0024 0.0116
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0065 0.0065
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0079 0.0458
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.001 0.0005 0.0005
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0024 0.0047
Brugia malayi AKH receptor 0.0199 0.0583 0.0852
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0009 0.0018
Schistosoma mansoni alpha-1 adrenergic receptor 0.0199 0.0583 0.1156
Loa Loa (eye worm) hypothetical protein 0.1658 0.5045 0.7372
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0013 0.0013 0.0048
Echinococcus multilocularis Ankyrin 0.0017 0.0026 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0109
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0057 0.0149 0.0275
Schistosoma mansoni hypothetical protein 0.0044 0.0108 0.0214
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0009 0.0014
Entamoeba histolytica hypothetical protein 0.0025 0.0052 0.0289
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0018 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0037 0.0195
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0024 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Schistosoma mansoni hypothetical protein 0.1589 0.4832 0.9579
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0024 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0199 0.0583 0.0583
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.004 0.0058
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0029 0.015
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0017
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0199 0.0583 0.0852
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0362 0.2228
Onchocerca volvulus AMP deaminase 2 homolog 0.0174 0.0506 0.0967
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0005 0.0007
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0057 0.0149 0.0149
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0057 0.0149 0.0218
Loa Loa (eye worm) G-protein coupled receptor 0.0199 0.0583 0.0852
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0529 0.1048
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0057 0.0149 0.0275
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0005 0.0005
Onchocerca volvulus 0.0199 0.0583 0.1116
Schistosoma mansoni hypothetical protein 0.0313 0.0932 0.1848
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0466 0.1398 0.2036
Echinococcus multilocularis vesicular acetylcholine transporter 0.0885 0.268 0.268
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0362 0.2228
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0281 0.0835 0.1654
Onchocerca volvulus 0.001 0.0005 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0057 0.0083
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0109 0.0308 0.1853
Echinococcus granulosus neuropeptide receptor A26 0.0199 0.0583 0.1076
Mycobacterium ulcerans hypothetical protein 0.0109 0.0306 0.1838
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0013 0.0013 0.0048
Onchocerca volvulus 0.0026 0.0055 0.0096
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0029 0.0029
Brugia malayi hypoxia-induced factor 1 0.0173 0.0502 0.0734
Brugia malayi phosphofructokinase 0.0127 0.0362 0.0529
Echinococcus multilocularis AMP deaminase 2 0.0174 0.0506 0.0506
Echinococcus multilocularis ATP binding cassette sub family B 0.001 0.0005 0.0005
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0005 0.0009
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0035
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0079 0.0458
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0068 0.0344
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0199 0.0583 0.1156
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Schistosoma mansoni cpg binding protein 0.0032 0.0072 0.0142
Schistosoma mansoni bromodomain containing protein 0.0063 0.0168 0.0332
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0037 0.0045
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0024
Schistosoma mansoni amine GPCR 0.0199 0.0583 0.1156
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0024 0.0116
Leishmania major trypanothione reductase 0.0047 0.0118 0.0165
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Plasmodium falciparum AMP deaminase, putative 0.0174 0.0506 0.3127
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Echinococcus multilocularis GPCR, family 2 0.0145 0.0417 0.0417
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0037 0.0148
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0281 0.0835 0.0835
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0196 0.0573 0.1057
Trichomonas vaginalis inositol monophosphatase, putative 0.0122 0.0347 0.2137
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0005 0.000000000087994
Onchocerca volvulus Putative nachr subunit 0.0057 0.0149 0.0278
Onchocerca volvulus 0.0199 0.0583 0.1116
Loa Loa (eye worm) hypothetical protein 0.061 0.1839 0.2688
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.004 0.0073
Onchocerca volvulus 0.061 0.1839 0.3541
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.01 0.0146
Brugia malayi larval opioid receptor 0.0199 0.0583 0.0852
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0013 0.0013 0.0011
Brugia malayi hypothetical protein 0.0029 0.0064 0.0093
Schistosoma mansoni biogenic amine receptor 0.0199 0.0583 0.1156
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0027
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0018 0.0027
Onchocerca volvulus 0.0199 0.0583 0.1116
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.01 0.01
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0024 0.0027
Echinococcus multilocularis cpg binding protein 0.0032 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0046 0.0116 0.0169
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.01 0.0593
Schistosoma mansoni amine GPCR 0.0199 0.0583 0.1156
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0024 0.0116
Brugia malayi nuclear receptor RXR 0.0011 0.0009 0.0012
Trypanosoma cruzi ISWI complex protein 0.0015 0.0019 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.0199 0.0583 0.1076
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0057 0.0149 0.0295
Brugia malayi Tachykinin-like peptides receptor 99D 0.0199 0.0583 0.0852
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0222 0.1352
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0012
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.006 0.0158 0.0231
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.004 0.0078
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0018
Trichomonas vaginalis dullard protein, putative 0.0013 0.0012 0.0042
Brugia malayi ecdysone receptor 0.001 0.0005 0.0007
Plasmodium falciparum adenosine deaminase 0.0534 0.1607 1
Onchocerca volvulus 0.1658 0.5045 0.9727
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0013 0.0013 0.0024
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0199 0.0583 0.0852
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0009 0.0017
Brugia malayi CXXC zinc finger family protein 0.0029 0.0061 0.0089
Brugia malayi Fli-1 protein 0.0214 0.0628 0.0917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Trypanosoma cruzi ISWI complex protein 0.0015 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.036 0.1075 0.1571
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0012 0.0042
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.004 0.004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0079 0.0458
Schistosoma mansoni myo inositol monophosphatase 0.0013 0.0013 0.0026
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0037 0.0199
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0037 0.0148
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0037 0.0148
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni adenoreceptor 0.0199 0.0583 0.1156
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0081
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0021
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Onchocerca volvulus 0.0139 0.0397 0.0758
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0046 0.0046
Echinococcus granulosus transcription factor Dp 1 0.0045 0.011 0.0203
Mycobacterium tuberculosis Conserved protein 0.0041 0.01 0.0593
Onchocerca volvulus 0.0044 0.0108 0.0199
Brugia malayi exodeoxyribonuclease III family protein 0.0081 0.0222 0.0324
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.004 0.0073
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0005 0.0009
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0009 0.0017
Schistosoma mansoni multidrug resistance protein 0.001 0.0005 0.001
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0024 0.0116
Echinococcus granulosus AMP deaminase 2 0.0174 0.0506 0.0933
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0026 0.0055 0.0101
Brugia malayi tailless protein 0.001 0.0005 0.0007
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0079 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Onchocerca volvulus 0.0232 0.0684 0.131
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0024 0.0116
Echinococcus granulosus lamin 0.0027 0.0057 0.0105
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.01 0.0547
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.1658 0.5045 0.7372
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0108 0.064
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0053 0.0136 0.0269
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0037 0.0195
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0009 0.0025
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0127 0.0362 0.219
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0052 0.0062
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.004 0.0058
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.004 0.0073
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0029 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0064 0.0085
Schistosoma mansoni ap endonuclease 0.0081 0.0222 0.044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0081 0.0149
Leishmania major myo-inositol-1 phosphatase, putative 0.0013 0.0013 0.0011
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0005 0.001
Brugia malayi excitatory GABA receptor EXP-1A 0.0057 0.0149 0.0218
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.01 0.0593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0037 0.0195
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0122 0.0347 0.05
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0122 0.0347 0.2137
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0057 0.0149 0.0218
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0193 0.0281
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Plasmodium falciparum glutathione reductase 0.0016 0.0024 0.012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0108 0.0108
Onchocerca volvulus 0.0041 0.01 0.0184
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0059
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0012 0.0009 0.0029
Schistosoma mansoni netrin receptor unc5 0.0017 0.0025 0.005
Schistosoma mansoni biogenic amine receptor 0.0199 0.0583 0.1156
Schistosoma mansoni hypothetical protein 0.0145 0.0417 0.0827
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.004 0.0078
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0123 0.035 0.2156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0199 0.0583 0.1156
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.001 0.0005 0.0009
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0123 0.018
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0108 0.0199
Echinococcus granulosus short transient receptor potential channel 6 0.0067 0.0179 0.033
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0018 0.0081
Echinococcus granulosus sodium and chloride dependent glycine 0.0281 0.0835 0.154
Echinococcus multilocularis neuropeptides capa receptor 0.0199 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0041 0.01 0.0146
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.01 0.0185
Onchocerca volvulus 0.0027 0.0057 0.0101
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0057 0.0149 0.0275
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0005 0.0005
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0029 0.0029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0199 0.0583 0.1076
Echinococcus multilocularis G protein coupled receptor 139 0.0351 0.1047 0.1047
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0199 0.0583 0.0852
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.021 0.1276
Trypanosoma brucei ISWI complex protein 0.0015 0.0019 0.0015
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0081 0.0222 0.0324
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0024 0.012
Schistosoma mansoni myosin xvIII 0.0199 0.0583 0.1156
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0018 0.0018
Loa Loa (eye worm) inositol-1 0.0122 0.0347 0.0508
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0037 0.0148
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0081 0.0222 0.0409
Brugia malayi isocitrate dehydrogenase 0.0018 0.0029 0.0043
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0024 0.0116
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.003 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0149 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0199 0.0583 0.0583
Echinococcus granulosus neuropeptide s receptor 0.0199 0.0583 0.1076
Echinococcus granulosus short transient receptor potential channel 6 0.0067 0.0179 0.033
Brugia malayi mbt repeat family protein 0.0049 0.0123 0.018
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0024 0.0035
Schistosoma mansoni rab6-interacting 0.0044 0.0108 0.0214
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0061 0.016 0.0234
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0014 0.0014
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0057 0.0149 0.0218
Trypanosoma brucei trypanothione reductase 0.0047 0.0118 0.0159
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0005 0.0007
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0057 0.0149 0.0218
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.004 0.0078
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0008
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0018 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0025 0.0025
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0199 0.0583 0.1156
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Loa Loa (eye worm) hypothetical protein 0.0534 0.1607 0.2348
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0093 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0199 0.0583 0.1076
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0022 0.0023
Mycobacterium leprae Possible regulatory protein 0.0015 0.0018 0.0033
Trichomonas vaginalis adenosine deaminase, putative 0.0534 0.1607 1
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0068 0.01
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0304 0.1824
Echinococcus granulosus tm gpcr rhodopsin 0.0199 0.0583 0.1076
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0885 0.268 0.5163
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0058
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.01 0.0199
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.01
Loa Loa (eye worm) neuropeptide F receptor 0.0199 0.0583 0.0852
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0081 0.0222 0.1352
Brugia malayi beta-lactamase family protein 0.0041 0.01 0.0146
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.021 0.0293
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Loa Loa (eye worm) hypothetical protein 0.0145 0.0417 0.061
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Brugia malayi nuclear receptor NHR-67 0.001 0.0005 0.0007
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0021 0.0031
Echinococcus granulosus serine:threonine protein kinase SMG1 0.001 0.0006 0.0011
Echinococcus granulosus geminin 0.1589 0.4832 0.8914
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0024 0.0116
Schistosoma mansoni acetylcholine receptor subunit beta 0.0026 0.0055 0.0108
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0079 0.0531
Schistosoma mansoni lipoxygenase 0.0117 0.0332 0.0658
Trichomonas vaginalis inositol monophosphatase, putative 0.0013 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0057 0.0149 0.0218
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0057 0.0149 0.0149
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0237 0.0237
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.035 0.2153
Loa Loa (eye worm) hypothetical protein 0.0281 0.0835 0.122
Leishmania major adenine aminohydrolase 0.0534 0.1607 0.2342
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0123 0.035 0.0504
Brugia malayi Muscleblind-like protein 0.0153 0.0442 0.0646
Leishmania major C-8 sterol isomerase-like protein 0.2246 0.6843 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.003 0.006
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0037 0.0148
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0199 0.0583 0.1156
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0458
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0024 0.0026
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0025 0.0049
Echinococcus multilocularis ets variant gene 4 0.001 0.0005 0.0005
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0005 0.0009
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0157 0.0157
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0024 0.0021
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0013 0.0013 0.0048
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0057 0.0149 0.0218
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0199 0.0583 0.1156
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0534 0.1607 1
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0108 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.004 0.0058
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0083
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0281 0.0835 0.122
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0122 0.0347 0.0495
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0145 0.0417 0.077
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.0127 0.0362 0.0522
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0199 0.0583 0.0583
Schistosoma mansoni thyroid hormone receptor 0.0022 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.0199 0.0583 0.0852
Leishmania major hypothetical protein, conserved 0.0015 0.0019 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Echinococcus granulosus serotonin transporter 0.1658 0.5045 0.9307
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0037 0.0195
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0033 0.0065
Echinococcus multilocularis RUN 0.0044 0.0108 0.0108
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0005 0.0005
Echinococcus multilocularis multidrug resistance protein 1 0.001 0.0005 0.0005
Echinococcus multilocularis glycine receptor subunit beta 0.0057 0.0149 0.0149
Schistosoma mansoni vesicular amine transporter 0.0217 0.0638 0.1264
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0304 0.1863
Echinococcus granulosus bloom syndrome protein 0.0025 0.0049 0.009
Leishmania major hypothetical protein, conserved 0.0041 0.01 0.0139
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0362 0.2228
Brugia malayi hypothetical protein 0.0199 0.0583 0.0852
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0222 0.1355
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0013 0.0013 0.0011
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.0145 0.0287
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.004 0.0078
Mycobacterium leprae conserved hypothetical protein 0.0041 0.01 0.0547
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0081 0.0081
Echinococcus granulosus nAChR subunit 0.0057 0.0149 0.0275
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0021
Brugia malayi hypothetical protein 0.0026 0.0055 0.008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.01 0.0593
Leishmania major protein kinase, putative 0.0021 0.0039 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0025 0.0049
Schistosoma mansoni ap endonuclease 0.0081 0.0222 0.044
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.01 0.0199
Loa Loa (eye worm) neuropeptide F receptor 0.0199 0.0583 0.0852
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0037 0.0045
Schistosoma mansoni neuropeptide F-like receptor 0.0199 0.0583 0.1156
Echinococcus granulosus adenosine deaminase 0.0534 0.1607 0.2964
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0024 0.0026
Echinococcus multilocularis synaptic vesicular amine transporter 0.0217 0.0638 0.0638
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0123 0.0244
Schistosoma mansoni hypothetical protein 0.0199 0.0583 0.1156
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0024 0.0116
Brugia malayi Calcitonin receptor-like protein seb-1 0.0458 0.1376 0.2011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.008
Loa Loa (eye worm) hypothetical protein 0.0153 0.0442 0.0646
Brugia malayi Death domain containing protein 0.0017 0.0025 0.0037
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0031 0.0068 0.01
Brugia malayi Protein kinase domain containing protein 0.0018 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0012
Echinococcus multilocularis mitogen activated protein kinase 3 0.0123 0.035 0.035
Brugia malayi CCR4 0.0016 0.0024 0.0035
Schistosoma mansoni nAChR subunit 0.0057 0.0149 0.0295
Onchocerca volvulus 0.0139 0.0397 0.0758
Onchocerca volvulus 0.0199 0.0583 0.1116
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0118 0.0706
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0024 0.0116
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0012 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0529 0.0529
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0037 0.0148
Trypanosoma brucei AMP deaminase, putative 0.0174 0.0506 0.0726
Onchocerca volvulus 0.0199 0.0583 0.1116
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0068 0.0099
Loa Loa (eye worm) GABA receptor subunit 0.0031 0.0068 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0006 0.0003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.004 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0359 0.0524
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0004 0.0008
Schistosoma mansoni histamine h1 receptor 0.0199 0.0583 0.1156
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0079 0.0461
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0281 0.0835 0.154
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.01 0.0593
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0024 0.0035
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.003 0.0044
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0037 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0157
Toxoplasma gondii thioredoxin reductase 0.0047 0.0118 0.0709
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.015 0.0904
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0199 0.0583 0.0852
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0281 0.0835 0.1654
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0139 0.0397 0.0788

Activities

Activity type Activity value Assay description Source Reference
DC50 (binding) = 8.7 uM Ability to interact with DNA was assessed by a DNA/ethidium bromide dye displacement assay, expressed as DC50 for polydAdT ChEMBL. 11965367
IC50 (functional) = 4.6 uM Compound was evaluated for cytotoxic activity against human melanoma cell line SK-Mel-5 ChEMBL. 11965367
IC50 (functional) = 4.6 uM Compound was evaluated for cytotoxic activity against human melanoma cell line SK-Mel-5 ChEMBL. 11965367
IC50 (functional) = 5.4 uM Compound was evaluated for cytotoxic activity against human melanoma cell line A375 ChEMBL. 11965367
IC50 (functional) = 5.4 uM Compound was evaluated for cytotoxic activity against human melanoma cell line A375 ChEMBL. 11965367
IC50 (functional) = 6.5 uM Compound was evaluated for cytotoxic activity against the following human cancer cell Breast cancer cell line T47 D ChEMBL. 11965367
IC50 (functional) = 6.5 uM Compound was evaluated for cytotoxic activity against the following human cancer cell Breast cancer cell line T47 D ChEMBL. 11965367
IC50 (functional) = 7.2 uM Compound was evaluated for cytotoxic activity against the following human cancer cell MDR Uterine cancer cell line Mes-SA/Dx5 ChEMBL. 11965367
IC50 (functional) = 7.2 uM Compound was evaluated for cytotoxic activity against the following human cancer cell MDR Uterine cancer cell line Mes-SA/Dx5 ChEMBL. 11965367
IC50 (functional) = 8.5 uM Compound was evaluated for cytotoxic activity against human ovarian cancer cell line SK-OV-3 ChEMBL. 11965367
IC50 (functional) = 8.5 uM Compound was evaluated for cytotoxic activity against human ovarian cancer cell line SK-OV-3 ChEMBL. 11965367
IC50 (functional) = 9.1 uM Compound was evaluated for cytotoxic activity against human breast cancer cell line MDA-MB-231 ChEMBL. 11965367
IC50 (functional) = 9.1 uM Compound was evaluated for cytotoxic activity against human breast cancer cell line MDA-MB-231 ChEMBL. 11965367
IC50 (functional) = 10 uM Compound was evaluated for cytotoxic activity against human prostate cancer cell line PC-3 ChEMBL. 11965367
IC50 (functional) = 10 uM Compound was evaluated for cytotoxic activity against human prostate cancer cell line PC-3 ChEMBL. 11965367
IC50 (functional) = 10.1 uM Compound was evaluated for cytotoxic activity against the following human cancer cell Uterine cancer cell line Mes-SA ChEMBL. 11965367
IC50 (functional) = 10.1 uM Compound was evaluated for cytotoxic activity against the following human cancer cell Uterine cancer cell line Mes-SA ChEMBL. 11965367

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11965367

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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