Detailed information for compound 350641

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 469.813 | Formula: C22H16ClF4NO4
  • H donors: 1 H acceptors: 2 LogP: 4.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1O/C(=C\c2cc(ccc2Cl)C(F)(F)F)/C(=C1c1ccc(c(c1)F)N1CCOCC1)O
  • InChi: 1S/C22H16ClF4NO4/c23-15-3-2-14(22(25,26)27)9-13(15)11-18-20(29)19(21(30)32-18)12-1-4-17(16(24)10-12)28-5-7-31-8-6-28/h1-4,9-11,29H,5-8H2/b18-11-
  • InChiKey: SLEMINBFDUIZIX-WQRHYEAKSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylenolpyruvoylglucosamine reductase Get druggable targets OG5_131886 All targets in OG5_131886
Treponema pallidum UDP-N-acetylenolpyruvoylglucosamine reductase Get druggable targets OG5_131886 All targets in OG5_131886
Mycobacterium leprae PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE) Get druggable targets OG5_131886 All targets in OG5_131886
Mycobacterium ulcerans UDP-N-acetylenolpyruvoylglucosamine reductase Get druggable targets OG5_131886 All targets in OG5_131886
Mycobacterium tuberculosis Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase) Get druggable targets OG5_131886 All targets in OG5_131886
Chlamydia trachomatis UDP-N-acetylenolpyruvoylglucosamine reductase Get druggable targets OG5_131886 All targets in OG5_131886
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0051 0.005
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0023 0.005
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0037 0.0043 0.0041
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0021 0.0018 0.0018
Trichomonas vaginalis set domain proteins, putative 0.08 0.1176 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0112 0.0154 0.0352
Brugia malayi ImpB/MucB/SamB family protein 0.0089 0.0119 0.0271
Entamoeba histolytica hypothetical protein 0.0014 0.0008 0.0103
Echinococcus granulosus peptidase Clp S14 family 0.0099 0.0135 0.0135
Mycobacterium tuberculosis Conserved protein 0.0163 0.0229 0.0526
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0051 0.0119
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0018 0.0018
Leishmania major pantothenate kinase subunit, putative 0.0016 0.001 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0039 0.0045 0.0099
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0021 0.0018 0.0037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0023
Trypanosoma brucei unspecified product 0.0061 0.0078 0.0175
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.012 0.0166 0.0166
Mycobacterium ulcerans esterase/lipase LipP 0.0163 0.0229 0.0526
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0502
Leishmania major inosine-5-monophosphate dehydrogenase 0.2916 0.4318 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.005 0.0062 0.0139
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.013 0.018 0.3175
Trypanosoma brucei unspecified product 0.0061 0.0078 0.0175
Echinococcus granulosus histone lysine methyltransferase setb 0.0101 0.0138 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0191 0.0272 0.027
Echinococcus multilocularis retinol dehydrogenase 13 0.0021 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0042 0.005 0.0848
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Leishmania major guanosine monophosphate reductase 0.2916 0.4318 1
Plasmodium vivax hypothetical protein, conserved 0.0191 0.0272 0.0643
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.001 0.0002 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0002 0.0002
Echinococcus multilocularis integrin beta 2 0.0103 0.0141 0.0141
Echinococcus multilocularis geminin 0.0646 0.0947 0.0947
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0272 0.027
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Echinococcus granulosus hypothetical protein 0.0021 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0078 0.0175
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0062 0.0144
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0038 0.0043 0.0096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0132 0.0183 0.042
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0193 0.0274 0.0631
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0051 0.0119
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0191 0.0272 0.0272
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Mycobacterium tuberculosis Probable oxidoreductase 0.0175 0.0248 0.0569
Entamoeba histolytica sphingomyelinase C precursor, putative 0.001 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0078 0.018
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0018 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0028 0.006
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0002 0.0005
Trypanosoma cruzi FHA domain containing protein, putative 0.0016 0.0011 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0132 0.0183 0.3231
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0103 0.0103
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0042 0.005 0.009
Schistosoma mansoni hypothetical protein 0.0033 0.0036 0.0034
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0039 0.0045 0.0099
Chlamydia trachomatis Mg++ transporter 0.0081 0.0108 0.1124
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0011 0.0078
Leishmania major hypothetical protein, conserved 0.0081 0.0108 0.0246
Trypanosoma cruzi importin beta-1 subunit, putative 0.0014 0.0008 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0158 0.0222 0.0508
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0051 0.005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0051 0.0119
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0012 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.001 0.0002 0.0004
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0021 0.0018 0.0037
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0045 0.01
Brugia malayi Inositol monophosphatase family protein 0.001 0.0002 0.0001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0079 0.0105 0.1828
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0128 0.0177 0.0177
Echinococcus granulosus expressed protein 0.0026 0.0026 0.0026
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0021 0.0018 0.0038
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0213
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.2916 0.4318 0.4318
Brugia malayi jmjC domain containing protein 0.0139 0.0194 0.0446
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0028 0.0061
Echinococcus multilocularis lamin 0.0015 0.0009 0.0009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0038 0.0043 0.0043
Leishmania major acetyl-CoA synthetase, putative 0.0039 0.0045 0.01
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0021 0.0018 0.0016
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0191 0.0272 0.0272
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0089 0.0119 0.027
Brugia malayi beta-lactamase family protein 0.0163 0.0229 0.0527
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0201 0.0286 0.0658
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Brugia malayi Integrin beta pat-3 precursor 0.014 0.0195 0.0447
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trichomonas vaginalis rotamase, putative 0.0026 0.0026 0.0204
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0201 0.0286 0.0658
Loa Loa (eye worm) IMP dehydrogenase 1 0.2916 0.4318 1
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0051 0.0115
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0103 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0051 0.0115
Entamoeba histolytica ubiquitin like protein 0.002 0.0017 0.0276
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0023 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0011 0.0021
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0038 0.0043 0.0096
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0081 0.0108 0.0245
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0021 0.0018 0.0038
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0018 0.0018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0128 0.0177 0.0177
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.001 0.0002 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0043 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0028 0.006
Onchocerca volvulus Sepiapterin reductase homolog 0.0021 0.0018 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0097
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Mycobacterium leprae Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) 0.0081 0.0108 0.0245
Schistosoma mansoni hypothetical protein 0.0136 0.0189 0.0187
Echinococcus multilocularis microtubule associated protein 2 0.6742 1 1
Plasmodium vivax glutathione reductase, putative 0.0069 0.009 0.021
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0021 0.0018 0.0037
Trichomonas vaginalis inositol monophosphatase, putative 0.001 0.0002 0.0004
Loa Loa (eye worm) inositol-1 0.0097 0.0131 0.0303
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0051 0.0115
Loa Loa (eye worm) RNA binding protein 0.0191 0.0272 0.0629
Echinococcus granulosus inositol monophosphatase 0.001 0.0002 0.0002
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0081 0.0108 0.0108
Mycobacterium ulcerans hypothetical protein 0.0163 0.0229 0.0526
Plasmodium vivax JmjC domain containing protein 0.0037 0.0043 0.0097
Leishmania major hypothetical protein, conserved 0.001 0.0002 0.0001
Brugia malayi Dehydrogenases, short chain protein 30 0.0021 0.0018 0.0038
Onchocerca volvulus 0.0015 0.0009 0.0041
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0191 0.0272 0.027
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0002 0.0001
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.005 0.0062 0.0139
Schistosoma mansoni ran 0.0012 0.0006 0.0004
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0081 0.0108 0.0245
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0018 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0128 0.0177 0.0177
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0021 0.0018 0.0038
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.0043 0.0094
Brugia malayi Dehydrogenases, short chain protein 2 0.0021 0.0018 0.0038
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Echinococcus multilocularis sterol regulatory element binding protein 0.0034 0.0038 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Echinococcus granulosus Small ubiquitin modifier 2 0.002 0.0017 0.0017
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0018 0.0037
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0078 0.0103 0.0233
Loa Loa (eye worm) dehydrogenase 0.0021 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0152 0.0213 0.0492
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0018 0.0018
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0002 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0163 0.0229 0.1939
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0051 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0051 0.0115
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0048
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.012 0.0166 0.0384
Toxoplasma gondii CBS domain-containing protein 0.0081 0.0108 0.0246
Leishmania major hypothetical protein, conserved 0.0021 0.0018 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Toxoplasma gondii thioredoxin reductase 0.0069 0.009 0.0204
Plasmodium falciparum DNA repair protein REV1, putative 0.0027 0.0028 0.0063
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0002 0.0005
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0038 0.0044 0.0096
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0087 0.0116 0.0263
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Brugia malayi ancient conserved domain protein 2 0.0081 0.0108 0.0246
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0021 0.0018 0.0042
Trypanosoma cruzi transcription factor btf3, putative 0.0019 0.0016 0.0033
Toxoplasma gondii ABC1 family protein 0.0163 0.0229 0.0527
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0081 0.0108 0.0108
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0023 0.0049
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0039 0.0045 0.0099
Onchocerca volvulus 0.0021 0.0018 0.0089
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1042 0.1534 0.355
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0175 0.0248 0.0569
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0051 0.0269
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0066 0.0146
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Echinococcus granulosus traf and tnf receptor associated protein 0.001 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0276 0.0397 0.0395
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0087 0.0116 0.0263
Mycobacterium tuberculosis Probable reductase 0.0158 0.0222 0.0508
Schistosoma mansoni survival motor neuron protein 0.0136 0.0189 0.0187
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0022 0.0022
Leishmania major endonuclease/exonuclease protein-like protein 0.001 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.031
Echinococcus multilocularis L aminoadipate semialdehyde 0.0149 0.0209 0.0209
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0039 0.0045 0.01
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0021 0.0018 0.0037
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0983 0.1448 0.3353
Leishmania major hypothetical protein, conserved 0.0021 0.0018 0.0038
Schistosoma mansoni niemann-pick C1 (NPC1) 0.008 0.0106 0.0105
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.001 0.0002 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0018 0.0038
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0201 0.0286 0.0286
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0051 0.0051
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.005 0.0062 0.0139
Brugia malayi jmjC domain containing protein 0.0037 0.0043 0.0094
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0158 0.0222 0.0508
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0097 0.0131 0.0299
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0039 0.0045 0.0104
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0163 0.0229 0.0526
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0002 0.001
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0021 0.0018 0.0038
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0012 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0051 0.0115
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0001
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0018 0.0037
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0045 0.0099
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0021 0.0018 0.0089
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0051 0.0269
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0018 0.0041
Onchocerca volvulus 0.006 0.0076 0.0401
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0045 0.0104
Echinococcus granulosus neuropeptide s receptor 0.116 0.171 0.171
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0021 0.0018 0.0017
Trypanosoma brucei trypanothione reductase 0.0069 0.009 0.0203
Echinococcus granulosus GPCR family 2 0.0128 0.0177 0.0177
Brugia malayi Pax transcription activation domain interacting protein 0.0016 0.0011 0.0021
Brugia malayi Niemann-Pick C1 protein precursor 0.0079 0.0105 0.0238
Toxoplasma gondii hypothetical protein 0.0052 0.0065 0.0146
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0021 0.0018 0.0017
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0021 0.0018 0.0038
Echinococcus multilocularis inositol monophosphatase 1 0.0097 0.0131 0.0131
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Schistosoma mansoni thyroid hormone receptor 0.0123 0.017 0.0168
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0097 0.0131 0.0131
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0034 0.0038 0.0087
Mycobacterium leprae Probable lipase LipE 0.0163 0.0229 0.0526
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.2835 0.4197 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.013 0.018 0.3175
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0025 0.0025 0.0053
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0018 0.0018
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0021 0.0018 0.014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0057 0.0072 0.0164
Leishmania major phosphopantetheinyl transferase-like protein 0.0042 0.005 0.011
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0002 0.0002
Chlamydia trachomatis DNA ligase 0.0016 0.0011 0.0092
Trypanosoma cruzi GMP reductase 0.2916 0.4318 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0031 0.0067
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0487
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0103 0.0233
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0051 0.005
Mycobacterium leprae PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE) 0.0643 0.0942 0.2178
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0103 0.0858
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0123 0.017 0.039
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0012 0.0006 0.0008
Mycobacterium ulcerans hypothetical protein 0.0081 0.0108 0.0245
Schistosoma mansoni pap-inositol-14-phosphatase 0.001 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Brugia malayi hypothetical protein 0.002 0.0018 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0272 0.027
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0081 0.0108 0.5937
Echinococcus granulosus integrin beta 2 0.0103 0.0141 0.0141
Leishmania major importin beta-1 subunit, putative 0.0014 0.0008 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0138 0.0136
Echinococcus granulosus steroid dehydrogenase 0.0021 0.0018 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0006 0.0009
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0039 0.0045 0.0103
Onchocerca volvulus 0.0191 0.0272 0.1461
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0081 0.0108 0.0108
Echinococcus granulosus lysine specific demethylase 6a 0.0037 0.0043 0.0043
Loa Loa (eye worm) serotonin transporter b 0.0191 0.0272 0.0629
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Treponema pallidum fructose-bisphosphate aldolase 0.013 0.018 0.1893
Schistosoma mansoni importin beta-1 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Trichomonas vaginalis esterase, putative 0.0163 0.0229 0.1939
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0051 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0132 0.0183 0.042
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0089 0.0119 0.0119
Plasmodium vivax replication factor C subunit 1, putative 0.0016 0.0011 0.0022
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0002 0.0001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.001 0.0002 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Loa Loa (eye worm) cysteine protease 0.001 0.0002 0.0004
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0149 0.0209 0.0479
Brugia malayi loechrig isoform VII 0.0081 0.0108 0.0246
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0018 0.0036
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0123 0.017 0.1437
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0039 0.0045 0.0099
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0132 0.0183 0.042
Brugia malayi hypothetical protein 0.0034 0.0038 0.0083
Leishmania major DNA polymerase kappa, putative 0.0089 0.0119 0.0271
Leishmania major myo-inositol-1 phosphatase, putative 0.001 0.0002 0.0001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0051 0.0051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.001 0.0002 0.0002
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0201 0.0286 0.0284
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0072 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0081 0.0108 0.025
Onchocerca volvulus 0.0021 0.0018 0.0089
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Echinococcus multilocularis cysteine protease 0.001 0.0002 0.0002
Echinococcus granulosus cpg binding protein 0.0017 0.0012 0.0012
Onchocerca volvulus 0.0021 0.0018 0.0089
Schistosoma mansoni jumonji/arid domain-containing protein 0.014 0.0196 0.0194
Plasmodium vivax acetyl-CoA synthetase, putative 0.0039 0.0045 0.0103
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0123 0.017 0.1437
Schistosoma mansoni carbon catabolite repressor protein 0.001 0.0002 0.0001
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0021 0.0018 0.0037
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0018 0.0038
Onchocerca volvulus 0.0039 0.0045 0.0233
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0012 0.0006 0.0189
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0062 0.0514
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0023 0.1155
Loa Loa (eye worm) hypothetical protein 0.0983 0.1448 0.3353
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.1582 0.2337 0.541
Echinococcus granulosus muscleblind protein 0.0343 0.0497 0.0497
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Brugia malayi Nuclear hormone receptor E75 0.002 0.0018 0.0036
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0011 0.0078
Trichomonas vaginalis Phospholipase C precursor, putative 0.001 0.0002 0.0005
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0021 0.0018 0.0038
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0103 0.0233
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0021 0.0018 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0089 0.0119 0.027
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0021 0.0018 0.0038
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0018 0.0018
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Loa Loa (eye worm) dehydrogenase 0.0021 0.0018 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0175 0.0248 0.0569
Loa Loa (eye worm) TAR-binding protein 0.0191 0.0272 0.0629
Trichomonas vaginalis rotamase, putative 0.0025 0.0025 0.0196
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.001 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Echinococcus granulosus replication factor c subunit 1 0.0016 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0132 0.0183 0.042
Brugia malayi oxidoreductase 0.0021 0.0018 0.0038
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.005 0.0062 0.0062
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Echinococcus granulosus thioredoxin glutathione reductase 0.0069 0.009 0.009
Mycobacterium ulcerans hypothetical protein 0.0081 0.0108 0.0245
Leishmania major oxidoreductase-like protein 0.0021 0.0018 0.0038
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Onchocerca volvulus 0.0021 0.0018 0.0089
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0051 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0051 0.0051
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0042 0.005 0.0502
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0018 0.0037
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Giardia lamblia Replication factor C, subunit 1 0.0016 0.0011 0.0483
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0152 0.0213 0.0502
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0103 0.0858
Loa Loa (eye worm) jmjC domain-containing protein 0.014 0.0196 0.0453
Toxoplasma gondii oxidoreductase, putative 0.0021 0.0018 0.0038
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0123 0.017 0.3
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0078 0.0103 0.5628
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.001 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.031
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0023 0.0048
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0021 0.0018 0.0018
Plasmodium vivax exodeoxyribonuclease III, putative 0.001 0.0002 0.0001
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Schistosoma mansoni acetyl-CoA synthetase 0.0039 0.0045 0.0043
Mycobacterium tuberculosis Probable hydrolase 0.0163 0.0229 0.0526
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Leishmania major trypanothione reductase 0.0069 0.009 0.0204
Brugia malayi nuclear hormone receptor 0.002 0.0018 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.012 0.0166 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0103 0.0858
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0021 0.0018 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0132
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0081 0.0108 0.0246
Entamoeba histolytica acyl-coA synthetase, putative 0.0132 0.0183 0.3231
Echinococcus multilocularis cpg binding protein 0.0017 0.0012 0.0012
Brugia malayi beta-NAC-like protein 0.0019 0.0016 0.0033
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0021 0.0049
Plasmodium falciparum small ubiquitin-related modifier 0.002 0.0017 0.0037
Brugia malayi Inositol monophosphatase family protein 0.001 0.0002 0.0001
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0052 0.0065 0.015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0089 0.0119 0.0117
Toxoplasma gondii isocitrate dehydrogenase 0.0021 0.0018 0.0038
Leishmania major short chain dehydrogenase, putative 0.0021 0.0018 0.0038
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.001 0.0002 0.0002
Mycobacterium ulcerans dehydrogenase 0.0021 0.0018 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0051 0.0051
Loa Loa (eye worm) chloride channel protein 7 0.0081 0.0108 0.025
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0408 0.0593 0.1369
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.2916 0.4318 0.4317
Schistosoma mansoni rotamase 0.0026 0.0026 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0045 0.01
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0016 0.0011 0.0078
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0021 0.0018 0.0037
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.005 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0272 0.027
Trypanosoma brucei small ubiquitin-related modifier 0.002 0.0017 0.0035
Toxoplasma gondii NAC domain-containing protein 0.0019 0.0016 0.0033
Trypanosoma brucei DNA polymerase IV, putative 0.0089 0.0119 0.027
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.001 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0033 0.0036 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0703 0.1032 0.2389
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0078 0.0103 0.0101
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0021 0.0018 0.0037
Brugia malayi beta-lactamase family protein 0.0163 0.0229 0.0527
Loa Loa (eye worm) hypothetical protein 0.0343 0.0497 0.1151
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0023 0.0049
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0012 0.0023
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.005 0.0062 0.336
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0081 0.0108 0.0106
Mycobacterium leprae conserved hypothetical protein 0.0042 0.005 0.0109
Echinococcus granulosus H:Cl exchange transporter 4 0.0081 0.0108 0.0108
Mycobacterium tuberculosis Probable dehydrogenase 0.0021 0.0018 0.0037
Echinococcus multilocularis survival motor neuron protein 1 0.0665 0.0974 0.0974
Echinococcus multilocularis cysteine protease 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Echinococcus multilocularis musashi 0.0015 0.0009 0.0009
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0191 0.0272 0.027
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0021 0.0018 0.0038
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0061 0.0078 0.135
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0042 0.005 0.0114
Trypanosoma cruzi chloride channel protein, putative 0.0081 0.0108 0.0246
Trypanosoma cruzi GMP reductase 0.2916 0.4318 1
Mycobacterium tuberculosis Probable lipase LipD 0.0163 0.0229 0.0526
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0081 0.0108 0.5937
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.0155 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0043 0.0095
Loa Loa (eye worm) hypothetical protein 0.0132 0.0183 0.0425
Brugia malayi Ubiquitin-like protein SMT3 0.002 0.0017 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Echinococcus multilocularis muscleblind protein 1 0.0343 0.0497 0.0497
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.001 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Toxoplasma gondii IMP dehydrogenas 0.2916 0.4318 1
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0018 0.0018
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0039 0.0045 0.01
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Loa Loa (eye worm) hypothetical protein 0.0103 0.0141 0.0326
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0081 0.0108 0.0246
Trichomonas vaginalis antibiotic synthetase, putative 0.0039 0.0045 0.0367
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Leishmania major short chain dehydrogenase, putative 0.0021 0.0018 0.0038
Trypanosoma cruzi chloride channel protein, putative 0.0081 0.0108 0.0246
Brugia malayi dehydrogenases, short chain protein 2 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0276 0.0397 0.0919
Brugia malayi CCR4 0.001 0.0002 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0093 0.0126 0.0286
Schistosoma mansoni peptidase Clp (S14 family) 0.0152 0.0213 0.0211
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0121
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0163 0.0229 0.0527
Brugia malayi Nuclear hormone receptor E75 0.002 0.0018 0.0036
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0378 0.0548 0.0548
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2916 0.4318 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0021 0.0018 0.0038
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Echinococcus multilocularis sodium and chloride dependent glycine 0.0983 0.1448 0.1448
Giardia lamblia Reductase, putative 0.0021 0.0018 0.0895
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0038 0.0044 0.0357
Leishmania major mitochondrial DNA polymerase beta 0.0408 0.0593 0.137
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0101 0.0138 0.0138
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0119 0.0271
Leishmania major cathepsin L-like protease 0.0037 0.0043 0.0095
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0051 0.0051
Brugia malayi DKFZp564C0469 protein 0.0016 0.0011 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0051 0.0115
Trichomonas vaginalis penicillin-binding protein, putative 0.0163 0.0229 0.1939
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0021 0.0018 0.0037
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0021 0.0018 0.0038
Brugia malayi Retinol dehydrogenase 12 0.0021 0.0018 0.0038
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0191 0.0272 0.027
Brugia malayi isocitrate dehydrogenase 0.0021 0.0018 0.0038
Leishmania major DNA polymerase eta, putative 0.0173 0.0245 0.0562
Mycobacterium ulcerans DNA polymerase IV 0.0089 0.0119 0.027
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0018 0.0037
Toxoplasma gondii small ubiquitin family modifier, putative 0.002 0.0017 0.0036
Echinococcus granulosus transcription factor btf3 0.0019 0.0016 0.0016
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0018 0.0018
Leishmania major DNA polymerase kappa, putative 0.0027 0.0028 0.0061
Plasmodium vivax importin-beta 2, putative 0.0017 0.0012 0.0025
Trypanosoma cruzi short chain dehydrogenase, putative 0.0021 0.0018 0.0038
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0016 0.0011 0.0021
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.001 0.0002 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0138 0.0136
Brugia malayi CHE-14 protein 0.0034 0.0038 0.0083
Echinococcus granulosus lamin dm0 0.0015 0.0009 0.0009
Onchocerca volvulus 0.001 0.0002 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Loa Loa (eye worm) loechrig isoform VII 0.0081 0.0108 0.025
Treponema pallidum hemolysin (tlyC) 0.0081 0.0108 0.1124
Brugia malayi hypothetical protein 0.0096 0.013 0.0296
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0066 0.0148
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0078 0.0175
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0021 0.0018 0.0016
Schistosoma mansoni retinal dehydrogenase 0.0021 0.0018 0.0016
Plasmodium falciparum glutathione reductase 0.0069 0.009 0.021
Schistosoma mansoni cpg binding protein 0.0016 0.0011 0.0009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0089 0.0119 0.0119
Schistosoma mansoni transcription factor btf3 0.0019 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Toxoplasma gondii ATPase, AAA family protein 0.0016 0.0011 0.0021
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0008 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Brugia malayi jmjC domain containing protein 0.014 0.0196 0.0449
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0039 0.0045 0.01
Toxoplasma gondii carbonyl reductase 1, putative 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0049 0.0113
Toxoplasma gondii hypothetical protein 0.0191 0.0272 0.0625
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0103 0.0232
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0021 0.0018 0.0037
Echinococcus granulosus lysine specific demethylase 5A 0.014 0.0196 0.0196
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0119 0.0271
Brugia malayi Isocitrate dehydrogenase 0.0021 0.0018 0.0038
Leishmania major hypothetical protein, conserved 0.0038 0.0044 0.0097
Toxoplasma gondii histone lysine methyltransferase SET1 0.0033 0.0037 0.0081
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0018 0.0036
Mycobacterium ulcerans acetyl-CoA synthetase 0.0039 0.0045 0.0099
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0051 0.0119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0629
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0039 0.0045 0.0099
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0123 0.017 0.0395
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0021 0.0018 0.0037
Trichomonas vaginalis DNA polymerase eta, putative 0.0089 0.0119 0.0996
Plasmodium falciparum thioredoxin reductase 0.0069 0.009 0.021
Trypanosoma brucei transcription factor BTF3, putative 0.0019 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0043 0.0098
Brugia malayi MH2 domain containing protein 0.0081 0.0107 0.0244
Echinococcus granulosus H:Cl exchange transporter 3 0.0081 0.0108 0.0108
Mycobacterium leprae Probable oxidoreductase 0.0021 0.0018 0.0037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0201 0.0286 0.0657
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0018 0.0037
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0983 0.1448 0.335
Trypanosoma brucei unspecified product 0.0089 0.0119 0.027
Treponema pallidum UDP-N-acetylenolpyruvoylglucosamine reductase 0.0643 0.0942 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0051 0.005
Brugia malayi Pre-SET motif family protein 0.0703 0.1032 0.2386
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0103 0.0103
Brugia malayi CLC chloride channel protein 0.0081 0.0108 0.0246
Echinococcus multilocularis protein dispatched 1 0.0039 0.0045 0.0045
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0012 0.0006 0.0009
Echinococcus multilocularis JmjC domain containing protein 4 0.0037 0.0043 0.0043
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0136 0.0189 0.0433
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0103 0.0233
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0191 0.0272 0.0625
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.001 0.0002 0.0001
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0097 0.0131 0.2297
Onchocerca volvulus 0.0015 0.0009 0.0041
Entamoeba histolytica transcription factor BTF3, putative 0.0019 0.0016 0.0252
Echinococcus multilocularis beta LACTamase domain containing family member 0.0163 0.0229 0.0229
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0123 0.017 0.1437
Brugia malayi Calcitonin receptor-like protein seb-1 0.0404 0.0587 0.1355
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0002 0.0001
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Loa Loa (eye worm) DR-78 0.002 0.0018 0.0041
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0042 0.005 0.0109
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0021 0.0018 0.0018
Echinococcus granulosus nibrin 0.0016 0.0011 0.0011
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0012 0.0006 0.0009
Schistosoma mansoni sodium/chloride dependent transporter 0.0984 0.1448 0.1447
Loa Loa (eye worm) hypothetical protein 0.0081 0.0108 0.025
Plasmodium falciparum glutathione reductase 0.0024 0.0023 0.005
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0051 0.0051
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Onchocerca volvulus 0.001 0.0002 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0016 0.0011 0.0162
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0025 0.0025 0.0052
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0023 0.0048
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0051 0.005
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0018 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0408 0.0593 0.137
Echinococcus multilocularis dna polymerase kappa 0.0089 0.0119 0.0119
Onchocerca volvulus 0.0149 0.0209 0.112
Echinococcus granulosus synaptojanin 1 0.001 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0017 0.0012 0.001
Mycobacterium ulcerans cystathionine beta-synthase 0.0081 0.0108 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0043 0.0351
Brugia malayi AMP-binding enzyme family protein 0.0132 0.0183 0.0421
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.005 0.0062 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0051 0.0115
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0039 0.0045 0.0099
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0132 0.0183 0.042
Plasmodium vivax small ubiquitin-related modifier, putative 0.002 0.0017 0.0037
Entamoeba histolytica hypothetical protein 0.0016 0.0011 0.0162
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0018 0.0293
Brugia malayi hypothetical protein 0.0016 0.0011 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0018 0.0085
Leishmania major hypothetical protein, conserved 0.0053 0.0066 0.0148
Echinococcus multilocularis lysine specific demethylase 6a 0.0037 0.0043 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0018 0.0037
Echinococcus granulosus sterol regulatory element binding protein 0.0034 0.0038 0.0038
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0101 0.0138 0.0314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0021 0.0018 0.0038
Mycobacterium ulcerans oxidoreductase 0.0021 0.0018 0.0037
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0045 0.0099
Toxoplasma gondii hypothetical protein 0.001 0.0002 0.0001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0132 0.0183 0.042
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0081 0.0108 0.0108
Entamoeba histolytica short chain dehydrogenase family protein 0.0021 0.0018 0.0293
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0021 0.0018 0.0895
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.002 0.0017 0.0016
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0002 0.0001
Entamoeba histolytica short chain dehydrogenase family protein 0.0021 0.0018 0.0293
Leishmania major acetyl-CoA synthetase, putative 0.0039 0.0045 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0066 0.0152
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0018 0.0037
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.2916 0.4318 1
Schistosoma mansoni cpg binding protein 0.0017 0.0012 0.001
Brugia malayi exodeoxyribonuclease III family protein 0.005 0.0062 0.014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0123 0.017 0.017
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0039 0.0045 0.0099
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0123 0.017 0.1437
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0213 0.0488
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0191 0.0272 0.0272
Trypanosoma brucei DNA polymerase IV, putative 0.0089 0.0119 0.027
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.012 0.0166 0.0164
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0078 0.0103 0.1791
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0021 0.0018 0.0037
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0018 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Echinococcus multilocularis lamin dm0 0.0015 0.0009 0.0009
Onchocerca volvulus 0.08 0.1176 0.6361
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0021 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0021 0.0018 0.0018
Brugia malayi dehydrogenases, short chain protein 9 0.0021 0.0018 0.0038
Schistosoma mansoni carbonyl reductase 0.0021 0.0018 0.0016
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.1582 0.2337 0.541
Schistosoma mansoni carbonyl reductase 0.0021 0.0018 0.0016
Giardia lamblia DNA damage repair protein 0.0027 0.0028 0.1447
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0272 0.027
Loa Loa (eye worm) papain family cysteine protease containing protein 0.001 0.0002 0.0004
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0021 0.0018 0.0038
Onchocerca volvulus 0.0016 0.0011 0.0049
Trypanosoma brucei oxidoreductase-like protein 0.0021 0.0018 0.0037
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0081 0.0108 0.0245
Echinococcus multilocularis snurportin 1 0.018 0.0255 0.0255
Schistosoma mansoni ap endonuclease 0.005 0.0062 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0045 0.0099
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0012 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0049
Loa Loa (eye worm) integrin beta-2 0.014 0.0195 0.0451
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0021 0.0018 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0121
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0039 0.0045 0.0099
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0193 0.0274 0.0629
Trypanosoma brucei protein kinase, putative 0.0038 0.0043 0.0094
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0023 0.005
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0025 0.0025 0.0053
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Schistosoma mansoni thyroid hormone receptor 0.0123 0.017 0.0168
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0042 0.005 0.0109
Onchocerca volvulus 0.002 0.0018 0.0085
Leishmania major chloride channel protein, putative 0.0081 0.0108 0.0246
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0093 0.0126 0.0286
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0097 0.0131 0.11
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0081 0.0108 0.0108
Giardia lamblia hypothetical protein 0.001 0.0002 0.0003
Brugia malayi nuclear receptor RXR 0.002 0.0018 0.0036
Onchocerca volvulus 0.0132 0.0183 0.0984
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0044 0.0044
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0132 0.0183 0.042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.005 0.0062 0.014
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0051 0.0115
Entamoeba histolytica hypothetical protein 0.0388 0.0564 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0646 0.0947 0.0946
Echinococcus granulosus snurportin 1 0.018 0.0255 0.0255
Loa Loa (eye worm) CXXC zinc finger family protein 0.0016 0.0011 0.0024
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0039 0.0045 0.01
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0132 0.0183 0.042
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0021 0.0018 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0093 0.0126 0.0286
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0039 0.0045 0.0104
Entamoeba histolytica hypothetical protein 0.0388 0.0564 1
Echinococcus granulosus Protein patched homolog 1 0.0034 0.0038 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0066 0.0148
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0028 0.006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0051 0.0115
Trypanosoma brucei hypothetical protein, conserved 0.0163 0.0229 0.0526
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0018 0.0293
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Schistosoma mansoni carbonyl reductase 0.0021 0.0018 0.0016
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0018 0.0018
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0018 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0037 0.0043 0.0094
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.2916 0.4318 1
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.001 0.0002 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0119 0.0271
Brugia malayi topoisomerase 0.0016 0.0011 0.0021
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0149 0.0209 0.0207
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0062 0.0514
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1078 0.1588 0.1588
Schistosoma mansoni intermediate filament proteins 0.0015 0.0009 0.0008
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0193 0.0274 0.0631
Schistosoma mansoni hypothetical protein 0.018 0.0255 0.0253
Echinococcus granulosus WW domain containing oxidoreductase 0.0021 0.0018 0.0018
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0038 0.0043 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0051 0.0119
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0105 0.0242
Loa Loa (eye worm) chloride channel 3 0.0081 0.0108 0.025
Trypanosoma brucei GMP reductase 0.2916 0.4318 1
Brugia malayi Kelch motif family protein 0.0021 0.0019 0.0039
Echinococcus multilocularis oxidoreductase 0.0021 0.0018 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0002 0.0006
Echinococcus granulosus inositol monophosphatase 1 0.0097 0.0131 0.0131
Giardia lamblia Hypothetical protein 0.0021 0.0018 0.0895
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.012 0.0166 0.0166
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0018 0.0037
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0123 0.017 0.0391
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0141 0.0139
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0011 0.0078
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0081 0.0108 0.0225
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0163 0.0229 0.0228
Plasmodium falciparum transporter, putative 0.0191 0.0272 0.0643
Trypanosoma brucei DNA polymerase eta, putative 0.0173 0.0245 0.0561
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0018 0.0018
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0051 0.0051
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0021 0.0019
Plasmodium falciparum replication factor C subunit 1, putative 0.0016 0.0011 0.0022
Schistosoma mansoni hypothetical protein 0.0033 0.0036 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0132 0.0183 0.0421
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0005
Echinococcus granulosus survival motor neuron protein 1 0.0665 0.0974 0.0974
Trypanosoma cruzi cruzipain precursor, putative 0.0037 0.0043 0.0095
Schistosoma mansoni coup transcription factor 0.0043 0.0051 0.005
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0018 0.0037
Echinococcus multilocularis transcription factor btf3 0.0019 0.0016 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0023 0.018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Onchocerca volvulus 0.0096 0.013 0.0693
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0021 0.0018 0.0016
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0002 0.0005
Mycobacterium ulcerans hypothetical protein 0.0027 0.0028 0.006
Entamoeba histolytica exodeoxyribonuclease III, putative 0.005 0.0062 0.1073
Schistosoma mansoni patched 1 0.0034 0.0038 0.0036
Echinococcus granulosus JmjC domain containing protein 4 0.0037 0.0043 0.0043
Loa Loa (eye worm) GMP reductase 0.1252 0.1847 0.4278
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0101 0.0138 0.0136
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0021 0.0018 0.0037
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0033 0.0037 0.008
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Brugia malayi hypothetical protein 0.0191 0.0272 0.0625
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.001 0.0002 0.0001
Mycobacterium tuberculosis Conserved protein 0.0163 0.0229 0.0526
Plasmodium falciparum acyl-CoA synthetase 0.0099 0.0134 0.0315
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0051 0.0051
Echinococcus granulosus cathepsin L cysteine proteinase 0.001 0.0002 0.0002
Trichomonas vaginalis inositol monophosphatase, putative 0.001 0.0002 0.0004
Onchocerca volvulus Putative neutral sphingomyelinase 0.001 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0097
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0023 0.0219
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.001 0.0002 0.0002
Brugia malayi hypothetical protein 0.0021 0.0019 0.0039
Brugia malayi jmjC domain containing protein 0.0037 0.0043 0.0094
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0163 0.0229 0.0526
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0021 0.0018 0.0293
Toxoplasma gondii hypothetical protein 0.0191 0.0272 0.0625
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Brugia malayi Importin beta-1 subunit 0.0017 0.0012 0.0024
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0021 0.0018 0.0038
Leishmania major basic transcription factor 3a, putative 0.0019 0.0016 0.0033
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0081 0.0108 0.0225
Loa Loa (eye worm) intermediate filament protein 0.0015 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0025
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylenolpyruvoylglucosamine reductase 0.0643 0.0942 0.2162
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0018 0.0039
Onchocerca volvulus 0.0021 0.0018 0.0089
Echinococcus multilocularis lysine specific demethylase 5A 0.0139 0.0194 0.0194
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0123 0.017 0.1437
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0404 0.0587 0.1355
Echinococcus multilocularis thioredoxin glutathione reductase 0.0069 0.009 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0066 0.0152
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.001 0.0002 0.0002
Trichomonas vaginalis ran, putative 0.0012 0.0006 0.0033
Schistosoma mansoni lamin 0.0015 0.0009 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.008 0.0106 0.0106
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.1252 0.1847 0.4276
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0052 0.0065 0.015
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0081 0.0108 0.0108
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0097 0.0131 0.0299
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0012 0.0006 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0002 0.0001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0038 0.0043 0.0094
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.005 0.0062 0.0144
Echinococcus granulosus phd:f box containing protein 0.0037 0.0043 0.0043
Brugia malayi Latrophilin receptor protein 2 0.0128 0.0177 0.0406
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0163 0.0229 0.1939
Loa Loa (eye worm) latrophilin receptor protein 2 0.0128 0.0177 0.041
Mycobacterium ulcerans lipase LipD 0.0163 0.0229 0.0526
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Loa Loa (eye worm) glutathione reductase 0.0069 0.009 0.0209
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Toxoplasma gondii exonuclease III APE 0.005 0.0062 0.014
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0099 0.0135 0.0307
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2916 0.4318 1
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0018 0.0018
Plasmodium falciparum DNase I-like protein, putative 0.001 0.0002 0.0001
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0018 0.0018
Echinococcus granulosus tar DNA binding protein 0.0191 0.0272 0.0272
Mycobacterium ulcerans hypothetical protein 0.0081 0.0108 0.0245
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0139 0.0194 0.0194
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Mycobacterium tuberculosis Conserved protein 0.0081 0.0108 0.0245
Toxoplasma gondii peptidylprolyl isomerase 0.0025 0.0025 0.0053
Brugia malayi tailless protein 0.002 0.0018 0.0036
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0201 0.0286 0.0286
Plasmodium falciparum exodeoxyribonuclease III, putative 0.001 0.0002 0.0001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0038 0.0043 0.0096
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0021 0.0018 0.014
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0043 0.0098
Plasmodium falciparum protein MAM3, putative 0.0081 0.0108 0.0253
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0015 0.0009 0.0022
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.001 0.0002 0.0002
Schistosoma mansoni cript-related 0.001 0.0002 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0163 0.0229 0.0531
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0081 0.0108 0.0106
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0042 0.005 0.0501
Echinococcus multilocularis neuropeptide s receptor 0.116 0.171 0.171
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.001 0.0002 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0028 0.0061
Loa Loa (eye worm) MH2 domain-containing protein 0.0081 0.0107 0.0248
Entamoeba histolytica deoxycytidyl transferase, putative 0.0089 0.0119 0.208
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0011 0.0078
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0028 0.0061
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.0272 0.0629
Leishmania major RNA-editing complex protein MP100, putative 0.001 0.0002 0.0001
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0021 0.0018 0.0038
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0018 0.0036
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0468
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.012 0.0166 0.0166
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0018 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni protein kinase subunit gamma 0.0081 0.0108 0.0106
Onchocerca volvulus 0.0136 0.0189 0.1012
Echinococcus multilocularis inositol monophosphatase 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0098
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.001 0.0002 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0049
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Trypanosoma cruzi DNA polymerase eta, putative 0.0112 0.0154 0.0352
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0191 0.0272 0.0272
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0062 0.0144
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0191 0.0272 0.027
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0002 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0021 0.0018 0.0018
Brugia malayi CBS domain containing protein 0.0081 0.0108 0.0246
Brugia malayi Thioredoxin reductase 0.0069 0.009 0.0204
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0051 0.005
Schistosoma mansoni myo inositol monophosphatase 0.001 0.0002 0.0001
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.1334 0.1968 0.4555
Brugia malayi conserved hypotetical protein 0.002 0.0018 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Trichomonas vaginalis steroid dehydrogenase, putative 0.0021 0.0018 0.014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0065
Trichomonas vaginalis D-aminoacylase, putative 0.0163 0.0229 0.1939
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0018 0.0013 0.0027
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0026 0.0026 0.0056
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0039 0.0045 0.0099
Echinococcus multilocularis expressed conserved protein 0.0074 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0128 0.0177 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0038 0.0305
Echinococcus granulosus beta LACTamase domain containing family member 0.0163 0.0229 0.0229
Toxoplasma gondii oxidoreductase, putative 0.0021 0.0018 0.0038
Brugia malayi polk-prov protein 0.0027 0.0028 0.0061
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0018 0.0041
Schistosoma mansoni microtubule-associated protein tau 0.6742 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0043 0.0098
Brugia malayi jmjC domain containing protein 0.0037 0.0043 0.0094
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0002 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0051 0.005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.005 0.0062 0.0119
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0021 0.0018 0.0037
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0018 0.0013 0.0027
Mycobacterium tuberculosis Probable esterase LipL 0.0163 0.0229 0.0526
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.001 0.002
Plasmodium falciparum importin beta, putative 0.0017 0.0012 0.0025
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0099 0.0134 0.1399
Onchocerca volvulus 0.0043 0.0051 0.0269
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0191 0.0272 0.027
Brugia malayi Probable ClpP-like protease 0.0152 0.0213 0.0488
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0018 0.0037
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0367 0.0532 0.1232
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0002 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0023 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0018 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0163 0.0229 0.1939
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.001 0.0002 0.001
Plasmodium vivax hypothetical protein, conserved 0.0163 0.0229 0.0542
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0097 0.0131 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0051 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Echinococcus multilocularis neutral sphingomyelinase 0.001 0.0002 0.0002
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0213
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0023 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0051 0.0051
Mycobacterium ulcerans hypothetical protein 0.0215 0.0306 0.0704
Giardia lamblia Kinase, CMGC MAPK 0.0038 0.0043 0.2289
Plasmodium falciparum thioredoxin reductase 0.0024 0.0023 0.005
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0081 0.0108 0.0245
Onchocerca volvulus Putative GMP reductase 0.1252 0.1847 1
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0001
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.2916 0.4318 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0099 0.0134 0.0305
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0018 0.0293
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0039 0.0045 0.0099
Echinococcus granulosus Niemann Pick C1 protein 0.0079 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0033 0.0036 0.0034
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0123 0.017 0.3
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0018 0.0037
Chlamydia trachomatis UDP-N-acetylenolpyruvoylglucosamine reductase 0.0643 0.0942 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0132 0.0183 0.0421
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0081 0.0108 0.025
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.2237
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0123 0.017 0.1437
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0039 0.0045 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Echinococcus granulosus L aminoadipate semialdehyde 0.0149 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0213 0.0488
Echinococcus multilocularis muscleblind protein 0.0343 0.0497 0.0497
Echinococcus granulosus sodium and chloride dependent glycine 0.0983 0.1448 0.1448
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0051 0.0115
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0601 0.088 0.2034
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.001 0.0002 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Mycobacterium tuberculosis Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase) 0.0643 0.0942 0.2178
Schistosoma mansoni DNA polymerase IV / kappa 0.0027 0.0028 0.0026
Schistosoma mansoni ap endonuclease 0.005 0.0062 0.006
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0018 0.0293
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0039 0.0045 0.0099
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0016 0.0011 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0043 0.0095
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0018 0.0089
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Echinococcus granulosus jumonji domain containing 1A 0.0037 0.0043 0.0043
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.001 0.0002 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.012 0.0166 0.0166
Schistosoma mansoni terminal deoxycytidyl transferase 0.0089 0.0119 0.0117
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0021 0.0018 0.0037
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0023 0.0028
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0016 0.0011 0.002
Brugia malayi nuclear hormone receptor 0.0043 0.0051 0.0115
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.2237
Loa Loa (eye worm) hypothetical protein 0.0132 0.0183 0.0425
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0018 0.0018
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0152 0.0213 0.0487
Schistosoma mansoni ran 0.0012 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Leishmania major DNA damage repair protein, putative 0.0027 0.0028 0.0061
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Echinococcus multilocularis nibrin 0.0016 0.0011 0.0011
Brugia malayi Voltage gated chloride channel family protein 0.0081 0.0108 0.0246
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Toxoplasma gondii CBS domain-containing protein 0.0081 0.0108 0.0246
Schistosoma mansoni phd/f-box containing protein 0.0037 0.0043 0.0041
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0018 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0191 0.0272 0.0272
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0021 0.0018 0.004
Echinococcus multilocularis jumonji domain containing 1A 0.0037 0.0043 0.0043
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Loa Loa (eye worm) thioredoxin reductase 0.0069 0.009 0.0209
Schistosoma mansoni DNA ligase IV 0.0016 0.0011 0.0009
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0081 0.0108 0.5937
Entamoeba histolytica hypothetical protein 0.0019 0.0016 0.0252
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0021
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0038 0.0043 0.0096
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0039 0.0045 0.0099
Echinococcus multilocularis GPCR, family 2 0.0128 0.0177 0.0177
Schistosoma mansoni sodium/chloride dependent transporter 0.0983 0.1448 0.1446
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0078 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0201 0.0286 0.0657
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0022
Entamoeba histolytica hypothetical protein 0.0388 0.0564 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Schistosoma mansoni nocturnin 0.001 0.0002 0.0001
Brugia malayi TAR-binding protein 0.0191 0.0272 0.0625
Onchocerca volvulus 0.0163 0.0229 0.1233
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0038 0.0043 0.0096
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0097 0.0131 0.0299
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Echinococcus multilocularis expressed protein 0.0026 0.0026 0.0026
Leishmania major cathepsin L-like protease 0.0037 0.0043 0.0095
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.012 0.0166 0.038
Schistosoma mansoni hypothetical protein 0.0128 0.0177 0.0175
Echinococcus granulosus hypothetical protein 0.0021 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0096 0.013 0.03
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0023 0.0049
Schistosoma mansoni neutral sphingomyelinase 0.001 0.0002 0.0001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.2236
Schistosoma mansoni DNA polymerase eta 0.0173 0.0245 0.0243
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0099 0.0135 0.0307
Leishmania major DNA polymerase eta, putative 0.0112 0.0154 0.0352
Leishmania major CBS domain protein, conserved 0.0081 0.0108 0.0246
Loa Loa (eye worm) norepinephrine transporter 0.0191 0.0272 0.0629
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0018 0.0018
Chlamydia trachomatis CBS domain-containing protein 0.0081 0.0108 0.1124
Treponema pallidum NADH oxidase 0.0024 0.0023 0.0218
Leishmania major hypothetical protein, conserved 0.0037 0.0043 0.0094
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0191 0.0272 0.0272
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0002 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Giardia lamblia DINP protein human, muc B family 0.0089 0.0119 0.6542
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0191 0.0272 0.0625
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0191 0.0272 0.027
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0042 0.005 0.011
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Leishmania major short chain dehydrogenase/reductase, putative 0.0021 0.0018 0.0038
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Mycobacterium ulcerans DNA polymerase IV 0.0089 0.0119 0.027
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0043 0.0351
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0119
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0018 0.0018
Brugia malayi RNA binding protein 0.0191 0.0272 0.0625
Brugia malayi RNA, U transporter 1 0.0048 0.0058 0.0131
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Echinococcus granulosus serotonin transporter 0.0191 0.0272 0.0272
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.018 0.0255 0.059
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0045 0.0099
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0039 0.0045 0.0099
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0081 0.0108 0.0245
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Brugia malayi photoreceptor-specific nuclear receptor 0.0367 0.0532 0.1228
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0983 0.1448 0.3353
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0081 0.0108 0.0246
Giardia lamblia Hypothetical protein 0.0081 0.0108 0.5937
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0023
Brugia malayi Intermediate filament tail domain containing protein 0.0015 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0051 0.0051
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0069 0.009 0.0203
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Echinococcus granulosus expressed conserved protein 0.0074 0.0097 0.0097
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0081 0.0108 0.0246
Echinococcus multilocularis conserved hypothetical protein 0.0021 0.0018 0.0018
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0081 0.0108 0.0245
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0051 0.0115
Onchocerca volvulus 0.002 0.0018 0.0085
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0057 0.0072 0.0162
Loa Loa (eye worm) beta-lactamase 0.0163 0.0229 0.0531
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0175 0.0248 0.0569
Schistosoma mansoni sodium-dependent amino acid transporter 0.0191 0.0272 0.027
Echinococcus granulosus intermediate filament protein 0.0015 0.0009 0.0009
Leishmania major 3-keto-dihydrosphingosine reductase 0.0021 0.0018 0.0038
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0066 0.0148
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0021 0.0018 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0051 0.0115
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0016 0.0011 0.0021
Onchocerca volvulus 0.0039 0.0045 0.0233
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0098
Plasmodium vivax hypothetical protein, conserved 0.001 0.0002 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0101 0.0138 0.0138
Mycobacterium tuberculosis Conserved hypothetical protein 0.0215 0.0306 0.0704
Onchocerca volvulus 0.0039 0.0045 0.0233
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0293
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0018 0.0036
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0132 0.0183 0.0421
Schistosoma mansoni synaptojanin 0.001 0.0002 0.0001
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0038 0.0044 0.0357
Trichomonas vaginalis inositol monophosphatase, putative 0.0097 0.0131 0.11
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0042 0.005 0.0114
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0039 0.0045 0.0099
Loa Loa (eye worm) fibroinase 0.001 0.0002 0.0004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Brugia malayi MAP kinase sur-1 0.0038 0.0043 0.0096
Onchocerca volvulus 0.0016 0.0011 0.0047
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.2916 0.4318 1
Trichomonas vaginalis CMGC family protein kinase 0.0038 0.0043 0.0351
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0002 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0021 0.0045
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0052 0.0065 0.0145
Trypanosoma cruzi DNA polymerase eta, putative 0.0173 0.0245 0.0562
Echinococcus multilocularis ubiquitin specific protease 41 0.0078 0.0103 0.0103
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni nuclear receptor 0.002 0.0018 0.0016
Echinococcus multilocularis replication factor c subunit 1 0.0016 0.0011 0.0011
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0081 0.0108 0.0108
Trypanosoma cruzi trypanothione reductase, putative 0.0069 0.009 0.0204
Loa Loa (eye worm) transcription factor SMAD2 0.0081 0.0107 0.0248
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.2916 0.4318 0.4318
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0018 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Echinococcus granulosus cathepsin l1 0.001 0.0002 0.0002
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0123 0.017 0.9447
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0051 0.0115
Schistosoma mansoni jumonji domain containing protein 0.0037 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Loa Loa (eye worm) solute carrier family 6 member 4 0.0191 0.0272 0.0629
Loa Loa (eye worm) ctsf protein 0.001 0.0002 0.0004
Echinococcus granulosus lamin 0.0015 0.0009 0.0009
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.001 0.0002 0.0001
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0081 0.0108 0.1124
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0085 0.0114 0.0259
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.0045 0.01
Onchocerca volvulus 0.0021 0.0018 0.0089
Plasmodium vivax DNA repair protein REV1, putative 0.0027 0.0028 0.0063
Echinococcus granulosus ubiquitin specific protease 41 0.0078 0.0103 0.0103
Treponema pallidum DNA ligase (lig) 0.0016 0.0011 0.0091
Loa Loa (eye worm) hypothetical protein 0.0078 0.0103 0.0237
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0128 0.0177 0.0406
Mycobacterium tuberculosis Conserved protein 0.0081 0.0108 0.0245
Trypanosoma cruzi chloride channel protein, putative 0.0081 0.0108 0.0246
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0051 0.005
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0037 0.0043 0.0094
Loa Loa (eye worm) hypothetical protein 0.0132 0.0183 0.0425
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0128 0.0177 0.0177
Schistosoma mansoni integrin beta subunit 0.0082 0.0109 0.0108
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0097 0.0131 0.0298
Schistosoma mansoni phosphatidylserine receptor 0.0037 0.0043 0.0041
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0018 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0045 0.01
Echinococcus multilocularis traf and tnf receptor associated protein 0.001 0.0002 0.0002
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0012 0.0006 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.001 0.0002 0.0001
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.008 0.0106 0.0106
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.012 0.0166 0.0164
Loa Loa (eye worm) hypothetical protein 0.0343 0.0497 0.1151
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0039 0.0045 0.01
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0018 0.0018
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0021 0.0018 0.0038
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0081 0.0108 0.0245
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.005 0.0062 0.014
Onchocerca volvulus 0.0021 0.0018 0.0089
Brugia malayi nuclear receptor RXR 0.0023 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Loa Loa (eye worm) hypothetical protein 0.0404 0.0587 0.1359
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0039 0.0045 0.0045
Giardia lamblia Short-chain dehydrogenase, putative 0.0021 0.0018 0.0895
Leishmania major hypothetical protein, conserved 0.0163 0.0229 0.0527
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0026 0.0026 0.006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0097 0.0131 0.11
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.001 0.0002 0.0009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.018 0.0255 0.059
Onchocerca volvulus 0.0021 0.0018 0.0089
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0132 0.0183 0.042
Echinococcus granulosus oxidoreductase 0.0021 0.0018 0.0018
Treponema pallidum exodeoxyribonuclease (exoA) 0.005 0.0062 0.0636
Schistosoma mansoni chromosome transmission fidelity factor 0.0016 0.0011 0.0009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0028 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0089 0.0119 0.0271
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0021 0.0018 0.0037
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0276 0.0398 0.0921
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0049
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0023 0.0048
Echinococcus multilocularis Niemann Pick C1 protein 0.0079 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.008 0.0106 0.0104
Loa Loa (eye worm) hypothetical protein 0.0128 0.0177 0.041
Leishmania major GTP-binding protein, putative 0.0012 0.0006 0.0009
Trichomonas vaginalis importin beta-1, putative 0.0014 0.0008 0.0049
Echinococcus multilocularis serotonin transporter 0.0191 0.0272 0.0272
Brugia malayi hypothetical protein 0.0053 0.0066 0.0148
Leishmania major hypothetical protein, conserved 0.001 0.0002 0.0001
Trypanosoma cruzi short chain dehydrogenase, putative 0.0021 0.0018 0.0038
Plasmodium vivax thioredoxin reductase, putative 0.0069 0.009 0.021
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0023 0.0049
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0039 0.0045 0.01
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0025 0.041
Trypanosoma brucei importin beta-1 subunit, putative 0.0017 0.0012 0.0023
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0018 0.0018
Onchocerca volvulus 0.0163 0.0229 0.1233
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.2835 0.4197 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Schistosoma mansoni chloride channel protein 0.0081 0.0108 0.0106
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Loa Loa (eye worm) hypothetical protein 0.0081 0.0108 0.025
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0081 0.0108 0.0245
Leishmania major small ubiquitin protein, putative 0.002 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0665 0.0974 0.2256
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Echinococcus multilocularis synaptojanin 1 0.001 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Schistosoma mansoni jumonji/arid domain-containing protein 0.014 0.0196 0.0194
Leishmania major hypothetical protein, conserved 0.0021 0.0018 0.0038
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Schistosoma mansoni sodium/chloride dependent transporter 0.0191 0.0272 0.027
Brugia malayi beta-lactamase 0.0163 0.0229 0.0527
Mycobacterium ulcerans short-chain type oxidoreductase 0.0021 0.0018 0.0037
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0018 0.0018
Echinococcus multilocularis phd:f box containing protein 0.0037 0.0043 0.0043
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0021 0.0018 0.0018
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0018 0.0037
Mycobacterium leprae conserved hypothetical protein 0.0081 0.0108 0.0245
Echinococcus granulosus geminin 0.0646 0.0947 0.0947
Echinococcus granulosus endonuclease exonuclease phosphatase 0.001 0.0002 0.0002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0191 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Brugia malayi jmjC domain containing protein 0.0037 0.0043 0.0094
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0028 0.006
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0021 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0163 0.0229 0.0527
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Leishmania major dehydrogenase-like protein 0.0021 0.0018 0.0038
Schistosoma mansoni hypothetical protein 0.0388 0.0564 0.0562
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0018 0.0018
Echinococcus multilocularis sodium and chloride dependent glycine 0.0983 0.1448 0.1448
Brugia malayi Muscleblind-like protein 0.0343 0.0497 0.1147
Schistosoma mansoni hypothetical protein 0.0646 0.0947 0.0946
Loa Loa (eye worm) hypothetical protein 0.0191 0.0272 0.0629
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0081 0.0108 0.0106
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0021 0.0018 0.0293
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0093 0.0126 0.0286
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2916 0.4318 1
Schistosoma mansoni zinc finger protein 0.002 0.0018 0.0016
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0099 0.0135 0.0307
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0002 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0021 0.0018 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.116 0.171 0.171
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0022 0.0022
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.001 0.0002 0.001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0139 0.0194 0.0194
Schistosoma mansoni transcription factor LCR-F1 0.0388 0.0564 0.0562
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0002 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.005 0.0062 0.014
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.001 0.0002 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0021 0.0018 0.0043
Schistosoma mansoni chloride channel protein 0.0081 0.0108 0.0106
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Echinococcus multilocularis deoxyribonuclease 1 2 0.001 0.0002 0.0002
Giardia lamblia Inositol 5-phosphatase 4 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0039 0.0045 0.0099
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0039 0.0045 0.0099
Brugia malayi ecdysone receptor 0.002 0.0018 0.0036
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0021 0.0018 0.0018
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0061 0.0078 0.135
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0051 0.005
Trypanosoma cruzi small ubiquitin protein, putative 0.002 0.0017 0.0036
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0016 0.0011 0.002
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0002 0.0001
Brugia malayi chloride channel protein 7 0.0081 0.0108 0.0246
Plasmodium vivax amine transporter, putative 0.0191 0.0272 0.0643
Leishmania major 4-coumarate:coa ligase-like protein 0.0132 0.0183 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Mycobacterium ulcerans beta-lactamase 0.0163 0.0229 0.0526
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Mycobacterium ulcerans UDP-N-acetylenolpyruvoylglucosamine reductase 0.0643 0.0942 0.2178
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0052 0.0065 0.0665
Giardia lamblia Fructose-bisphosphate aldolase 0.013 0.018 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Leishmania major hypothetical protein, conserved 0.001 0.0002 0.0001
Toxoplasma gondii hypothetical protein 0.0066 0.0085 0.0193
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0027 0.0028 0.0061
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0034 0.0038 0.0084
Schistosoma mansoni inositol monophosphatase 0.0097 0.0131 0.0129
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0163 0.0229 0.0526
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0002 0.0001
Plasmodium vivax steroid dehydrogenase, putative 0.0021 0.0018 0.0039
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0132 0.0183 0.042
Mycobacterium ulcerans dehydrogenase/reductase 0.0021 0.0018 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0121
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Brugia malayi hypothetical protein 0.0388 0.0564 0.1303
Brugia malayi hypothetical protein 0.0665 0.0974 0.2253
Trypanosoma cruzi small ubiquitin protein, putative 0.002 0.0017 0.0036
Leishmania major cathepsin L-like protease 0.0037 0.0043 0.0095
Schistosoma mansoni lamin 0.0015 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0138 0.0318
Loa Loa (eye worm) ICD-1 protein 0.0019 0.0016 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0037 0.0042 0.004
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0039 0.0045 0.0045
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0408 0.0593 0.137
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0103 0.0103
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0388 0.0564 0.0564
Echinococcus granulosus GTP binding nuclear protein Ran 0.0012 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Schistosoma mansoni protein phosphatase 2C 0.0037 0.0043 0.0041
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0039 0.0045 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0043 0.0041
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0021 0.0018 0.0037
Onchocerca volvulus 0.0191 0.0272 0.1461
Brugia malayi hypothetical protein 0.002 0.0018 0.0036
Brugia malayi nuclear receptor NHR-88 0.0043 0.0051 0.0115
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0006 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0021 0.0018 0.0038
Mycobacterium ulcerans oxidoreductase 0.0021 0.0018 0.0037
Onchocerca volvulus 0.0021 0.0018 0.0089
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0081 0.0108 0.0245
Plasmodium vivax SET domain protein, putative 0.0101 0.0138 0.0323
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0191 0.0272 0.027
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Brugia malayi Inositol-1 0.0097 0.0131 0.0299
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0018 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0011 0.0021
Trichomonas vaginalis replication factor C large subunit, putative 0.0016 0.0011 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Brugia malayi ancient conserved domain protein 4 0.0081 0.0108 0.0246
Leishmania major short chain dehydrogenase/reductase, putative 0.0021 0.0018 0.0038
Leishmania major chloride channel protein, putative 0.0081 0.0108 0.0246
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.001 0.0002 0.0001
Brugia malayi hypothetical protein 0.0023 0.0021 0.0045
Schistosoma mansoni hypothetical protein 0.0128 0.0177 0.0175
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0023 0.0048
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Loa Loa (eye worm) SMO-1 protein 0.002 0.0017 0.004
Onchocerca volvulus 0.0191 0.0272 0.1461
Schistosoma mansoni jumonji domain containing protein 0.0139 0.0194 0.0193
Plasmodium vivax acyl-CoA synthetase, putative 0.0099 0.0134 0.0315
Echinococcus multilocularis dna polymerase eta 0.0173 0.0245 0.0245
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0051 0.0051
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0008 0.0049
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Echinococcus multilocularis protein patched 0.0034 0.0038 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0048
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0021 0.0018 0.0037
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0021 0.0018 0.0037
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0038 0.0043 0.0096
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0163 0.0229 0.0228
Onchocerca volvulus 0.0123 0.017 0.0914
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0039 0.0045 0.01
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0023 0.0028
Brugia malayi latrophilin 2 splice variant baaae 0.0276 0.0397 0.0916
Loa Loa (eye worm) hypothetical protein 0.0163 0.0229 0.0531
Brugia malayi ecdysteroid receptor 0.0043 0.0051 0.0115
Schistosoma mansoni nuclear hormone receptor 0.002 0.0018 0.0016
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0025 0.0025 0.0053
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0021 0.0045
Echinococcus granulosus H:Cl exchange transporter 7 0.0081 0.0108 0.0108
Leishmania major pteridine reductase 1 0.0021 0.0018 0.0038
Onchocerca volvulus 0.0163 0.0229 0.1233
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0018 0.014
Leishmania major hypothetical protein, conserved 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0049
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0089 0.0119 0.0996
Entamoeba histolytica acyl-CoA synthetase, putative 0.0132 0.0183 0.3231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.0043 0.0094
Brugia malayi GMP reductase 0.1252 0.1847 0.4276
Onchocerca volvulus 0.0191 0.0272 0.1461
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0378 0.0548 0.0548
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0023 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.0163 0.0229 0.0526
Leishmania major short chain dehydrogenase-like protein 0.0021 0.0018 0.0038
Giardia lamblia Sentrin 0.002 0.0017 0.0842
Echinococcus multilocularis tumor protein p63 0.0706 0.1035 0.1035
Brugia malayi glutathione reductase 0.0069 0.009 0.0204
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0021 0.0018 0.0037
Brugia malayi hypothetical protein 0.0023 0.0021 0.0045
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0018 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0048
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0149 0.0209 0.0483
Trypanosoma cruzi hypothetical protein, conserved 0.0163 0.0229 0.0527
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Leishmania major hypothetical protein, conserved 0.0021 0.0018 0.0038
Echinococcus granulosus dna polymerase eta 0.0173 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.013 0.018 0.152
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0191 0.0272 0.027
Echinococcus granulosus sodium and chloride dependent glycine 0.0983 0.1448 0.1448
Loa Loa (eye worm) hypothetical protein 0.0173 0.0245 0.0566
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0601 0.088 0.2034
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0097 0.0131 0.0279
Schistosoma mansoni inositol monophosphatase 0.0097 0.0131 0.0129
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0201 0.0286 0.0657
Onchocerca volvulus 0.0103 0.0141 0.0752
Plasmodium falciparum steroid dehydrogenase, putative 0.0021 0.0018 0.0039
Plasmodium falciparum basic transcription factor 3b, putative 0.0019 0.0016 0.0034
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0044 0.0044
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0081 0.0108 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0042
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0021 0.0018 0.0037
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0081 0.0108 0.0108
Brugia malayi nuclear receptor NHR-67 0.002 0.0018 0.0036
Brugia malayi CXXC zinc finger family protein 0.0016 0.0011 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.0173 0.0245 0.0562
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0023 0.0049
Brugia malayi hypothetical protein 0.0016 0.0011 0.0021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0158 0.0222 0.0508
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0002 0.0001
Toxoplasma gondii CBS family protein 0.0081 0.0108 0.0246
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0016 0.0011 0.0021
Brugia malayi follicle stimulating hormone receptor 0.0276 0.0398 0.0917
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.031
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0002 0.0001
Schistosoma mansoni chloride channel protein 0.0081 0.0108 0.0106
Schistosoma mansoni hypothetical protein 0.0128 0.0177 0.0175
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0023 0.0048
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0002 0.0001
Brugia malayi steroid hormone receptor 0.0043 0.0051 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0043 0.0093
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0011 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0132 0.0183 0.0421
Onchocerca volvulus 0.0101 0.0138 0.0735
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.031
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0051 0.0119
Mycobacterium ulcerans transcriptional regulator 0.0081 0.0108 0.0245
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0042 0.005 0.0109
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0028 0.006
Mycobacterium tuberculosis Conserved protein 0.0163 0.0229 0.0526
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0097 0.0131 0.0298
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0037 0.0043 0.0093
Entamoeba histolytica hypothetical protein 0.0388 0.0564 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0021 0.0018 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0051 0.0051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0051 0.0115
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.007 0.0091 0.0207
Brugia malayi Pre-SET motif family protein 0.0101 0.0138 0.0314
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0018 0.0038
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0039 0.0045 0.0099
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0028 0.0061
Brugia malayi nuclear receptor NHR-88 0.002 0.0018 0.0036
Schistosoma mansoni synaptojanin 0.001 0.0002 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0023 0.0049
Onchocerca volvulus 0.0021 0.0018 0.0089
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0023 0.0049
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0021 0.0018 0.0038
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.001 0.0002 0.0001
Plasmodium falciparum amino acid transporter, putative 0.0191 0.0272 0.0643
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Entamoeba histolytica Ran family GTPase 0.0012 0.0006 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0018 0.0037
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0018 0.0293
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0045 0.0099
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0404 0.0587 0.1359
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0039 0.0045 0.0099
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0018 0.0038
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.2916 0.4318 1
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0021 0.0018 0.0037
Echinococcus multilocularis tar DNA binding protein 0.0191 0.0272 0.0272
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0021 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Echinococcus multilocularis importin subunit beta 1 0.0017 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0024 0.0022 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0011 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0101 0.0138 0.0136
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Trypanosoma cruzi transcription factor btf3, putative 0.0019 0.0016 0.0033
Trypanosoma cruzi chloride channel protein, putative 0.0081 0.0108 0.0246
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0016 0.0011 0.002
Echinococcus granulosus dna polymerase kappa 0.0089 0.0119 0.0119
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0018 0.0037
Mycobacterium ulcerans carveol-like dehydrogenase 0.0021 0.0018 0.0037
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0018 0.0037
Onchocerca volvulus 0.0081 0.0108 0.0575
Echinococcus multilocularis neuropeptide receptor A26 0.116 0.171 0.171
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0213 0.0487
Schistosoma mansoni nuclear receptor 0.002 0.0018 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0089 0.0119 0.027
Loa Loa (eye worm) oxidoreductase 0.0039 0.0045 0.0104
Treponema pallidum sodium- and chloride- dependent transporter 0.0191 0.0272 0.2863
Schistosoma mansoni topbp1 0.0016 0.0011 0.0009
Treponema pallidum Mg2+ transport protein (mgtE) 0.0081 0.0108 0.1124
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0039 0.0045 0.0766
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0158 0.0222 0.0508
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.2835 0.4197 0.972
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0023 0.005
Echinococcus granulosus cathepsin l cysteine peptidase 0.001 0.0002 0.0002
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.0272 0.0625
Mycobacterium leprae conserved hypothetical protein 0.0163 0.0229 0.0526
Toxoplasma gondii propionate-CoA ligase 0.0039 0.0045 0.01
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.2916 0.4318 1
Brugia malayi hypothetical protein 0.0021 0.0018 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0132 0.0183 0.042
Brugia malayi hypothetical protein 0.0021 0.0018 0.0038
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0018 0.0018
Echinococcus multilocularis mitogen activated protein kinase 0.0038 0.0043 0.0043
Mycobacterium ulcerans hypothetical protein 0.0132 0.0183 0.042
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0021 0.0019 0.0044
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0021 0.0019
Mycobacterium tuberculosis Probable dehydrogenase 0.0158 0.0222 0.0508
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0272 0.027
Onchocerca volvulus 0.0021 0.0018 0.0089
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0119 0.027
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0057 0.0072 0.0164
Mycobacterium tuberculosis Conserved protein 0.0081 0.0108 0.0245
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0158 0.0222 0.0508
Loa Loa (eye worm) hypothetical protein 0.0053 0.0066 0.0152
Echinococcus granulosus mitogen activated protein kinase 3 0.0038 0.0043 0.0043
Echinococcus granulosus tumor protein p63 0.0706 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0042 0.005 0.011
Plasmodium vivax basic transcription factor 3b, putative 0.0019 0.0016 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0078 0.0175
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0018 0.0018
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0018 0.0018
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0038 0.0043 0.0096
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0099 0.0134 0.0305
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0066 0.0152
Trypanosoma cruzi DNA polymerase kappa, putative 0.0089 0.0119 0.0271
Onchocerca volvulus 0.0021 0.0018 0.0089
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0021 0.0018 0.014
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0039 0.0045 0.0104
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0045 0.0099
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.1252 0.1847 0.4276
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0601 0.088 0.2034
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0051 0.0269
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0043 0.0095
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0018 0.0038
Schistosoma mansoni nuclear hormone receptor 0.002 0.0018 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0388 0.0564 0.0564
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0002 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0049
Echinococcus multilocularis peptidase Clp (S14 family) 0.0099 0.0135 0.0135
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0163 0.0229 0.0526
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0029
Echinococcus multilocularis Small ubiquitin modifier 2 0.002 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0051 0.0119
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.1334 0.1968 0.4555
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0021 0.0018 0.0039
Brugia malayi intermediate filament protein 0.0015 0.0009 0.0018
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0002 0.001
Echinococcus granulosus neutral sphingomyelinase 0.001 0.0002 0.0002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0089 0.0119 0.0275
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0041
Echinococcus granulosus mitogen activated protein kinase 0.0038 0.0043 0.0043
Trypanosoma brucei chrX additional, unordered contigs 0.0027 0.0028 0.006
Echinococcus granulosus importin subunit beta 1 0.0017 0.0012 0.0012
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0191 0.0272 0.2863
Loa Loa (eye worm) oxidoreductase 0.0021 0.0018 0.0042
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0023 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0011 0.0078
Schistosoma mansoni topbp1 0.0016 0.0011 0.0009
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0018 0.0016
Trichomonas vaginalis antibiotic synthetase, putative 0.0039 0.0045 0.0367
Plasmodium falciparum JmjC domain-containing protein, putative 0.0037 0.0043 0.0097

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 10 ug ml-1 Inhibitory activity against MurB in Escherichia coli ChEMBL. 16216496
IC50 (binding) = 10 ug ml-1 Inhibitory activity against MurB in Escherichia coli ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurA in Escherichia coli ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurC in Staphylococccus aureus ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurD in Staphylococccus aureus ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurA in Escherichia coli ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurC in Staphylococccus aureus ChEMBL. 16216496
IC50 (binding) > 25 ug ml-1 Inhibitory activity against MurD in Staphylococccus aureus ChEMBL. 16216496
MIC (functional) = 16 ug ml-1 Antibacterial activity against pencillin resistant Streptococcus pneumoniae ChEMBL. 16216496
MIC (functional) = 64 ug ml-1 Antibacterial activity against methicillin resistant Staphylococcus aureus ChEMBL. 16216496
MIC (functional) = 128 ug ml-1 Antibacterial activity against Staphylococcus aureus ChEMBL. 16216496
MIC (functional) = 128 ug ml-1 Antibacterial activity against vancomycin resistant Enterococcus faecalis ChEMBL. 16216496
MIC (functional) = 128 ug ml-1 Antibacterial activity against Enterococcus faecalis ChEMBL. 16216496

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.