Detailed information for compound 1372712

Basic information

Technical information
  • TDR Targets ID: 1372712
  • Name: [4-[(4-chlorophenyl)sulfanylmethyl]phenyl]-py rrolidin-1-ylmethanone
  • MW: 331.86 | Formula: C18H18ClNOS
  • H donors: 0 H acceptors: 1 LogP: 4.5 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)SCc1ccc(cc1)C(=O)N1CCCC1
  • InChi: 1S/C18H18ClNOS/c19-16-7-9-17(10-8-16)22-13-14-3-5-15(6-4-14)18(21)20-11-1-2-12-20/h3-10H,1-2,11-13H2
  • InChiKey: GUFOXFGOAZJHND-UHFFFAOYSA-N  

Network

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Synonyms

  • [4-[(4-chlorophenyl)sulfanylmethyl]phenyl]-pyrrolidin-1-yl-methanone
  • [4-[[(4-chlorophenyl)thio]methyl]phenyl]-1-pyrrolidinylmethanone
  • [4-[[(4-chlorophenyl)thio]methyl]phenyl]-pyrrolidin-1-yl-methanone
  • Oprea1_455213
  • 1-(4-{[(4-chlorophenyl)thio]methyl}benzoyl)pyrrolidine
  • MLS000684660
  • SMR000268534
  • ZINC00443716

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis mitogen activated protein kinase 0.0292 0.0358 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0371 0.0968
Giardia lamblia Kinase, CAMK CAMKL 0.0337 0.0462 0.2563
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Echinococcus multilocularis roundabout 2 0.0178 0.0099 0.0095
Giardia lamblia Kinase 0.0171 0.0084 0.0393
Echinococcus multilocularis expressed conserved protein 0.0347 0.0484 0.048
Trichomonas vaginalis STE family protein kinase 0.0332 0.045 0.2136
Schistosoma mansoni GTPase activating protein 0.0184 0.0114 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0084 0.0336
Loa Loa (eye worm) TK protein kinase 0.0772 0.1451 0.1617
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0566 0.0984 0.5562
Toxoplasma gondii STE kinase 0.0171 0.0084 0.0141
Echinococcus multilocularis TGF beta receptor type 1 0.0276 0.0322 0.0318
Echinococcus multilocularis heat shock protein 70 0.0171 0.0084 0.008
Entamoeba histolytica hypothetical protein 0.0159 0.0057 0.0257
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0313 0.0407 0.0453
Brugia malayi Protein kinase domain containing protein 0.1529 0.3176 0.3539
Plasmodium falciparum calcium-dependent protein kinase 7 0.0159 0.0057 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0533 0.1391
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0165 0.007 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi Protein kinase domain containing protein 0.0521 0.088 0.0979
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0171 0.0084 0.0336
Echinococcus multilocularis PAK box P21 Rho binding 0.0261 0.0288 0.0284
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Onchocerca volvulus 0.0412 0.0631 0.1398
Trypanosoma cruzi Protein kinase B 0.0566 0.0984 0.5562
Echinococcus multilocularis Immunoglobulin 0.0342 0.0473 0.0469
Echinococcus multilocularis cyclin dependent kinase 19 0.0547 0.0938 0.0935
Echinococcus granulosus neuroglian 0.0178 0.0099 0.0102
Trypanosoma cruzi casein kinase II, putative 0.0346 0.0481 0.2673
Echinococcus granulosus retinal guanylyl cyclase 2 0.0171 0.0084 0.0085
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1235 0.2506 0.2673
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0361 0.0515 0.2871
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0424 0.1105
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0346 0.0481 0.1255
Loa Loa (eye worm) TK/INSR protein kinase 0.1529 0.3176 0.354
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1134 0.2277 0.2428
Plasmodium falciparum tyrosine kinase-like protein, putative 0.023 0.0217 0.1764
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Echinococcus granulosus SH2 motif 0.0184 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0532 0.0904 0.1008
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0412 0.0631 0.0703
Loa Loa (eye worm) hypothetical protein 0.0514 0.0864 0.0963
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0031 0.0035
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0171 0.0084 0.0085
Loa Loa (eye worm) SRC-1 0.0771 0.1449 0.1615
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.134 0.2746 0.293
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Echinococcus granulosus nervana 2 0.0407 0.0621 0.0659
Giardia lamblia Kinase, CAMK CAMKL 0.0337 0.0462 0.2563
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Schistosoma mansoni hypothetical protein 0.0361 0.0515 0.1344
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Entamoeba histolytica casein kinase 1, putative 0.0412 0.0631 0.3063
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis tyrosine protein kinase Blk 0.0642 0.1156 0.1152
Echinococcus granulosus myotubularin protein 13 0.0196 0.014 0.0146
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis myotubularin protein 13 0.0196 0.014 0.0136
Trichomonas vaginalis STE family protein kinase 0.0332 0.045 0.2136
Echinococcus multilocularis tyrosine protein kinase Srms 0.0642 0.1156 0.1152
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0771 0.1449 0.1445
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0963 0.1886 0.2102
Trichomonas vaginalis TKL family protein kinase 0.0174 0.0089 0.0364
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0284 0.0341 0.038
Trichomonas vaginalis AGC family protein kinase 0.0547 0.0939 0.4536
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1559 0.3244 0.3462
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi integrin-linked kinase 0.0171 0.0084 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0296 0.0367 0.2022
Echinococcus granulosus mitogen activated protein kinase 11 0.0806 0.1528 0.1629
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1033 0.2045 0.2181
Loa Loa (eye worm) TK/EGFR protein kinase 0.1771 0.3726 0.4153
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0484 0.1263
Echinococcus multilocularis activated cdc42 kinase 1 0.0521 0.088 0.0876
Onchocerca volvulus 0.1394 0.2868 0.6483
Schistosoma mansoni protein kinase 0.0437 0.0689 0.18
Onchocerca volvulus 0.0749 0.14 0.3145
Entamoeba histolytica ankyrin repeat protein 0.0171 0.0084 0.0389
Echinococcus granulosus tyrosine protein kinase Src42A 0.0476 0.0778 0.0827
Plasmodium falciparum casein kinase 2, alpha subunit 0.0346 0.0481 0.4074
Giardia lamblia Kinase, PLK 0.0906 0.1756 1
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0771 0.1449 0.1445
Loa Loa (eye worm) AGC/PKG protein kinase 0.0347 0.0484 0.0539
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0547 0.0939 0.4566
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Toxoplasma gondii AGC kinase 0.0513 0.0861 0.4199
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0532 0.0904 0.7783
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0171 0.0084 0.0091
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0171 0.0084 0.0091
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Brugia malayi serine/threonine-protein kinase PAK 7 0.1166 0.235 0.2618
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Schistosoma mansoni tyrosine kinase 0.1771 0.3726 0.9754
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0171 0.0084 0.0215
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Brugia malayi probable protein kinase 0.0875 0.1686 0.1878
Echinococcus multilocularis titin 0.024 0.0241 0.0237
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.023 0.0217 0.0836
Entamoeba histolytica cell division protein kinase 2, putative 0.0588 0.1033 0.5024
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0084 0.0336
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis mitogen activated protein kinase 3 0.0292 0.0358 0.0354
Brugia malayi MAP kinase sur-1 0.0292 0.0358 0.0397
Echinococcus multilocularis tyrosine protein kinase csk 0.0171 0.0084 0.008
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0204 0.0159 0.0704
Echinococcus granulosus receptor type guanylyl cyclase 0.0171 0.0084 0.0085
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0292 0.0358 0.203
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi hypothetical protein 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0249 0.0261 0.0288
Brugia malayi Protein kinase domain containing protein 0.1034 0.2048 0.2282
Brugia malayi RhoGAP domain containing protein 0.0346 0.0481 0.0534
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Brugia malayi SH2 domain containing protein 0.0356 0.0504 0.0559
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0184 0.0114 0.011
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0806 0.1528 0.7449
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0304 0.0387 0.0409
Entamoeba histolytica PH domain containing protein kinase, putative 0.0566 0.0984 0.4785
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.0724 0.1891
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0141 0.0015 0.0012
Brugia malayi hypothetical protein 0.0361 0.0515 0.0572
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Schistosoma mansoni protein kinase 0.0322 0.0428 0.1116
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1159 0.2333 0.2601
Entamoeba histolytica hypothetical protein 0.0173 0.0087 0.0407
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0184 0.0114 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0388 0.0577 0.0613
Onchocerca volvulus 0.0369 0.0533 0.1174
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0412 0.0631 0.3538
Echinococcus granulosus cyclin dependent kinase 0.0588 0.1033 0.1099
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0346 0.0481 0.4074
Loa Loa (eye worm) thyroid receptor interactor 0.0299 0.0374 0.0417
Loa Loa (eye worm) casein kinase 0.0328 0.044 0.049
Echinococcus multilocularis twitchin 0.0211 0.0173 0.0169
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Onchocerca volvulus 0.0171 0.0084 0.0153
Plasmodium falciparum calcium-dependent protein kinase 5 0.0378 0.0553 0.4711
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0588 0.1033 0.1151
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0643 0.1158 0.6561
Echinococcus multilocularis tyrosine protein kinase shark 0.0585 0.1027 0.1023
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Giardia lamblia Kinase, CDC7 0.0369 0.0533 0.2973
Trypanosoma cruzi cdc2-related kinase 3 0.0588 0.1033 0.5843
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0579 0.1012 0.1127
Echinococcus granulosus tyrosine protein kinase otk 0.0148 0.0031 0.0029
Schistosoma mansoni atypical protein kinase C 0.1048 0.2079 0.5442
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0579 0.1011 0.1125
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0296 0.0367 0.2022
Trichomonas vaginalis CMGC family protein kinase 0.0641 0.1154 0.5592
Loa Loa (eye worm) hypothetical protein 0.0491 0.0811 0.0904
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0171 0.0084 0.0153
Entamoeba histolytica protein kinase, putative 0.0159 0.0057 0.0257
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0292 0.0358 0.1573
Loa Loa (eye worm) hypothetical protein 0.015 0.0035 0.0039
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) RGC/RGC protein kinase 0.0171 0.0084 0.0093
Echinococcus multilocularis 0.0489 0.0808 0.0804
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0771 0.1449 0.1445
Leishmania major protein kinase, putative 0.0159 0.0057 0.0313
Leishmania major serine/threonine-protein kinase, putative 0.0163 0.0066 0.0365
Trichomonas vaginalis STE family protein kinase 0.0261 0.0288 0.1338
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0451 0.1177
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.0861 0.225
Echinococcus granulosus dual specificity 0.0298 0.0371 0.0393
Trichomonas vaginalis TK family protein kinase 0.0174 0.0089 0.0364
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Brugia malayi Tyrosine-protein kinase abl-1 0.0827 0.1577 0.1756
Brugia malayi protein unc-22 0.024 0.0241 0.0267
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Schistosoma mansoni tyrosine kinase 0.0484 0.0797 0.2082
Brugia malayi C1-like domain containing protein 0.0817 0.1555 0.1732
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Brugia malayi Protein kinase domain containing protein 0.1365 0.2803 0.3123
Brugia malayi SH2 domain containing protein 0.0956 0.1871 0.2084
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0641 0.1154 0.5728
Brugia malayi Protein kinase domain containing protein 0.1035 0.2051 0.2285
Echinococcus granulosus cyclin dependent kinase 1 0.0588 0.1033 0.1099
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0817 0.1555 0.1732
Trypanosoma cruzi NIMA-related kinase, putative 0.0159 0.0057 0.0238
Echinococcus granulosus epidermal growth factor receptor 0.1235 0.2506 0.2673
Brugia malayi Tyrosine-protein kinase abl-1 0.0554 0.0954 0.1062
Trypanosoma cruzi aurora B kinase, putative 0.0547 0.0939 0.5305
Brugia malayi Immunoglobulin I-set domain containing protein 0.1119 0.2241 0.2497
Entamoeba histolytica protein kinase, putative 0.0234 0.0227 0.109
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0817 0.1555 0.1733
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0358 0.1683
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.134 0.2746 0.2743
Plasmodium vivax casein kinase 1, putative 0.0412 0.0631 0.5392
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0171 0.0084 0.0389
Entamoeba histolytica protein kinase, putative 0.0296 0.0367 0.1773
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0368 0.0532 0.0593
Echinococcus multilocularis beta adrenergic receptor kinase 0.0152 0.0039 0.0035
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0284 0.0341 0.036
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0249 0.0261 0.029
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0234 0.0227 0.1285
Loa Loa (eye worm) hypothetical protein 0.0693 0.1271 0.1417
Brugia malayi P38 map kinase family protein 2 0.0806 0.1528 0.1702
Echinococcus multilocularis tyrosine kinase 0.0356 0.0504 0.05
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0593 0.1045 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.014 0.0362
Echinococcus multilocularis mitogen activated protein kinase 14 0.0806 0.1528 0.1525
Giardia lamblia Kinase, CMGC MAPK 0.0292 0.0358 0.1968
Loa Loa (eye worm) hypothetical protein 0.0342 0.0473 0.0527
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Entamoeba histolytica hypothetical protein 0.0795 0.1503 0.7321
Schistosoma mansoni serine/threonine protein kinase 0.1048 0.2079 0.5441
Echinococcus granulosus tyrosine protein kinase Fyn 0.0771 0.1449 0.1544
Schistosoma mansoni nephrin 0.0178 0.0099 0.0256
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) hypothetical protein 0.0392 0.0585 0.0652
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0484 0.0797 0.2082
Echinococcus multilocularis dual specificity 0.0298 0.0371 0.0368
Brugia malayi Protein kinase domain containing protein 0.0234 0.0227 0.0251
Trichomonas vaginalis AGC family protein kinase 0.0284 0.0341 0.16
Echinococcus granulosus dual specificity protein kinase clk2 0.0643 0.1158 0.1233
Toxoplasma gondii histone kinase SNF1, putative 0.0321 0.0424 0.1916
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0292 0.0358 0.1968
Echinococcus granulosus insulin receptor 0.1529 0.3176 0.3389
Schistosoma mansoni serine/threonine protein kinase 0.0853 0.1637 0.4282
Entamoeba histolytica protein kinase, putative 0.0234 0.0227 0.109
Echinococcus granulosus TGF beta receptor type 1 0.0276 0.0322 0.0339
Giardia lamblia Kinase, AGC PKA 0.0532 0.0904 0.5107
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0677 0.1235 0.1377
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0853 0.1637 0.1745
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0368 0.0532 0.0591
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0184 0.0114 0.0125
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0184 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Echinococcus multilocularis cyclin dependent kinase 1 0.0588 0.1033 0.1029
Schistosoma mansoni protein kinase C mu 0.0817 0.1555 0.4068
Echinococcus multilocularis growth factor receptor bound protein 2 0.0313 0.0407 0.0403
Echinococcus granulosus hypothetical protein 0.0184 0.0114 0.0117
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0249 0.0261 0.0257
Schistosoma mansoni protein kinase 0.0296 0.0367 0.0958
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0254 0.0271 0.0302
Entamoeba histolytica protein kinase, putative 0.0296 0.0367 0.1773
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0196 0.014 0.0156
Leishmania major protein kinase A catalytic subunit isoform 2 0.0513 0.0861 0.4897
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0171 0.0084 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.0341 0.0889
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0641 0.1154 0.1286
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0171 0.0084 0.0091
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0031 0.0035
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0184 0.0114 0.0117
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Echinococcus granulosus natriuretic peptide receptor 1 0.0171 0.0084 0.0085
Echinococcus multilocularis 0.0514 0.0864 0.0861
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0588 0.1033 0.1099
Echinococcus multilocularis cyclin dependent kinase 9 0.022 0.0194 0.019
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0159 0.0057 0.0238
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Echinococcus granulosus twitchin 0.0553 0.0952 0.1013
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Echinococcus multilocularis tyrosine kinase 0.0171 0.0084 0.008
Schistosoma mansoni septate junction protein 0.0148 0.0031 0.0078
Echinococcus granulosus protein kinase 0.0171 0.0084 0.0085
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0937 0.1828 0.2038
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus granulosus peroxidasin 0.015 0.0035 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.0861 0.225
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0234 0.0227 0.1217
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trichomonas vaginalis CMGC family protein kinase 0.0588 0.1033 0.4996
Echinococcus granulosus tyrosine protein kinase csk 0.0171 0.0084 0.0085
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0321 0.0424 0.2405
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1196 0.2417 0.2694
Trypanosoma brucei casein kinase I, isoform 2 0.0412 0.0631 0.3077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Plasmodium vivax tyrosine kinase-like protein, putative 0.0171 0.0084 0.0599
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1159 0.2333 0.2489
Entamoeba histolytica tyrosin kinase, putative 0.0171 0.0084 0.0389
Echinococcus granulosus SHC transforming protein 3 0.0184 0.0114 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0853 0.1637 0.1823
Onchocerca volvulus 0.024 0.0241 0.0511
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0383 0.0565 0.0629
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0337 0.0462 0.3907
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0332 0.045 0.0446
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Schistosoma mansoni signal transduction protein lnk-related 0.0184 0.0114 0.0293
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0808 0.1533 0.1529
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0171 0.0084 0.0141
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0642 0.1156 0.1231
Schistosoma mansoni protein tyrosine kinase 0.0171 0.0084 0.0215
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1333 0.2729 0.3042
Loa Loa (eye worm) guanylate kinase 0.0135 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.1159 0.2333 0.26
Echinococcus granulosus casein kinase I delta 0.0412 0.0631 0.067
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0254 0.0271 0.0302
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0089 0.0364
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0298 0.0371 0.2107
Brugia malayi Variant SH3 domain containing protein 0.0313 0.0407 0.0451
Leishmania major protein kinase, putative 0.0547 0.0939 0.5341
Echinococcus multilocularis peroxidasin 0.015 0.0035 0.0031
Entamoeba histolytica SH2 domain containing protein 0.0184 0.0114 0.0535
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Echinococcus granulosus casein kinase I delta 0.0412 0.0631 0.067
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) AGC/PKA protein kinase 0.0513 0.0861 0.0959
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0171 0.0084 0.008
Schistosoma mansoni kinase 0.0966 0.1894 0.4957
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0039 0.0098
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0378 0.0553 0.2593
Brugia malayi SRC-1 0.0771 0.1449 0.1613
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0643 0.1158 0.6561
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0089 0.0364
Brugia malayi intracellular kinase 0.0641 0.1154 0.1284
Echinococcus multilocularis Glutaredoxin protein 5 0.0407 0.0621 0.0617
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Schistosoma mansoni tyrosine kinase 0.1235 0.2506 0.6558
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1159 0.2333 0.26
Leishmania major protein kinase, putative 0.0404 0.0613 0.3483
Giardia lamblia Kinase, CMGC SRPK 0.0234 0.0227 0.1217
Toxoplasma gondii diacylglycerol kinase, putative 0.0161 0.0061 0.0022
Brugia malayi diacylglycerol kinase 0.0161 0.0061 0.0066
Entamoeba histolytica protein kinase, putative 0.0173 0.0087 0.0407
Brugia malayi RhoGAP domain containing protein 0.0161 0.0061 0.0066
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0145 0.0023 0.0025
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0356 0.0504 0.244
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Loa Loa (eye worm) hypothetical protein 0.0491 0.0811 0.0904
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0163 0.0066 0.0365
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0806 0.1528 0.869
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Loa Loa (eye worm) hypothetical protein 0.1343 0.2751 0.3066
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1314 0.2685 0.2865
Echinococcus granulosus Protein kinase C brain isozyme 0.0889 0.1719 0.1833
Echinococcus granulosus activin receptor type 0.1068 0.2126 0.2267
Toxoplasma gondii protein kinase 0.0171 0.0084 0.0141
Brugia malayi Variant SH3 domain containing protein 0.0223 0.0202 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.1159 0.2333 0.6107
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0148 0.0031 0.0027
Echinococcus granulosus serine/threonine protein kinase 0.0566 0.0984 0.1047
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0818 0.087
Entamoeba histolytica protein kinase domain containing protein 0.0547 0.0939 0.4566
Schistosoma mansoni tyrosine kinase 0.1812 0.382 1
Onchocerca volvulus 0.0184 0.0114 0.0221
Echinococcus granulosus unc 13 munc13 0.0165 0.007 0.0071
Brugia malayi Kinase associated domain 1 family protein 0.029 0.0355 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0673 0.1226 0.5948
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0161 0.0061 0.0068
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus granulosus rho-associated protein kinase 1 0.1394 0.2868 0.306
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0806 0.1529 0.4001
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Schistosoma mansoni tyrosine protein kinase 0.0171 0.0084 0.0215
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0171 0.0084 0.0215
Echinococcus granulosus growth factor receptor bound protein 2 0.0319 0.0419 0.0444
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1314 0.2685 0.2682
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0857
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0169 0.0079 0.0314
Entamoeba histolytica serine/threonine protein kinase, putative 0.0906 0.1756 0.8558
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0178 0.0099 0.0095
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0184 0.0114 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Trichomonas vaginalis CAMK family protein kinase 0.0304 0.0387 0.1824
Giardia lamblia Kinase, NEK 0.0464 0.0751 0.4225
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi map kinase activated protein kinase protein 2 0.1314 0.2685 0.2992
Schistosoma mansoni rac gtpase activating protein 0.0161 0.0061 0.0155
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0437 0.0689 0.0766
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0171 0.0084 0.0085
Plasmodium vivax tyrosine kinase-like protein, putative 0.023 0.0217 0.1764
Schistosoma mansoni cell adhesion molecule 0.0178 0.0099 0.0256
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0257 0.0279 0.0294
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0682 0.1247 0.1243
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0963 0.1886 0.2101
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0165 0.007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0208 0.0167 0.0185
Plasmodium falciparum casein kinase 1 0.0412 0.0631 0.5392
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0358 0.1683
Echinococcus granulosus serine:threonine protein kinase N2 0.0877 0.1691 0.1803
Echinococcus multilocularis casein kinase i 0.0412 0.0631 0.0627
Loa Loa (eye worm) TK protein kinase 0.0171 0.0084 0.0093
Onchocerca volvulus 0.0356 0.0504 0.1108
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0296 0.0367 0.1791
Onchocerca volvulus 0.0171 0.0084 0.0153
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1613 0.3367 0.3753
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0493 0.0816 0.0868
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0084 0.0215
Echinococcus granulosus tyrosine protein kinase Fyn 0.0771 0.1449 0.1544
Entamoeba histolytica protein kinase domain containing protein 0.0795 0.1503 0.7321
Trichomonas vaginalis AGC family protein kinase 0.0547 0.0939 0.4536
Echinococcus granulosus calcium dependent protein kinase 0.0253 0.027 0.0284
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0547 0.0938 0.1046
Echinococcus granulosus TGF-beta receptor type-1 0.0276 0.0322 0.0339
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1048 0.2079 0.2076
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0298 0.0371 0.2046
Echinococcus multilocularis cyclin dependent kinase 7 0.0287 0.0347 0.0343
Trichomonas vaginalis AGC family protein kinase 0.0638 0.1147 0.5558
Loa Loa (eye worm) TK protein kinase 0.0171 0.0084 0.0093
Schistosoma mansoni cell adhesion molecule 0.0434 0.0683 0.1784
Giardia lamblia Kinase, STE STE20 0.0437 0.0689 0.387
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0171 0.0084 0.0093
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0437 0.0689 0.387
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0404 0.0613 0.2987
Entamoeba histolytica protein kinase, putative 0.0284 0.0341 0.1646
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0171 0.0084 0.0085
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0906 0.1756 0.1753
Echinococcus granulosus cGMP dependent protein kinase 0.0347 0.0484 0.0513
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0099 0.0109
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1166 0.235 0.2619
Plasmodium falciparum NIMA related kinase 4 0.0163 0.0066 0.0443
Schistosoma mansoni serine/threonine protein kinase 0.0841 0.1608 0.4208
Toxoplasma gondii aurora kinase 0.0547 0.0939 0.4605
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0806 0.1528 0.869
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Echinococcus granulosus integrin linked protein kinase 0.0171 0.0084 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0643 0.1158 0.3027
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0184 0.0114 0.011
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0395 0.0594 0.066
Loa Loa (eye worm) haspin protein kinase 0.0141 0.0015 0.0017
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0638 0.1147 0.1278
Echinococcus granulosus Diacylglycerol kinase theta 0.0161 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0547 0.0939 0.4536
Loa Loa (eye worm) hypothetical protein 0.0518 0.0874 0.0974
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.0938 0.2453
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Onchocerca volvulus 0.0356 0.0504 0.1108
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Plasmodium falciparum protein kinase 5 0.0588 0.1033 0.8906
Schistosoma mansoni tyrosine kinase 0.1064 0.2116 0.5537
Trichomonas vaginalis STE family protein kinase 0.0437 0.0689 0.3309
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0171 0.0084 0.008
Schistosoma mansoni suppressor of cytokine signaling 0.0184 0.0114 0.0293
Entamoeba histolytica hypothetical protein, conserved 0.0142 0.0016 0.006
Entamoeba histolytica receptor protein kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Trichomonas vaginalis protein tyrosine kinase, putative 0.0171 0.0084 0.0336
Echinococcus multilocularis neuroglian 0.0428 0.0669 0.0665
Echinococcus multilocularis calcium activated potassium channel 0.0415 0.0639 0.0635
Giardia lamblia Kinase, CMGC GSK 0.0641 0.1154 0.654
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0378 0.0553 0.2593
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Entamoeba histolytica protein kinase domain containing protein 0.0141 0.0015 0.0055
Echinococcus granulosus protein kinase 0.0514 0.0864 0.0919
Echinococcus multilocularis lachesin 0.0148 0.0031 0.0027
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0513 0.0861 0.4858
Echinococcus multilocularis dual specificity protein kinase clk2 0.0643 0.1158 0.1154
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0595 0.1048 0.1168
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0378 0.0553 0.2698
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0332 0.045 0.0446
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0169 0.0079 0.0314
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0171 0.0084 0.0093
Entamoeba histolytica protein kinase, putative 0.0795 0.1503 0.7321
Schistosoma mansoni protein kinase C mu 0.0161 0.0061 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0877 0.1691 0.4425
Plasmodium falciparum NIMA related kinase 1 0.0464 0.0751 0.6439
Echinococcus granulosus hypothetical protein 0.0518 0.0874 0.0929
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0298 0.0371 0.0412
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0159 0.0057 0.0362
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0057 0.0203
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Onchocerca volvulus 0.0356 0.0504 0.1108
Leishmania major casein kinase, putative 0.0412 0.0631 0.3588
Entamoeba histolytica hypothetical protein 0.0832 0.1588 0.7735
Echinococcus multilocularis nervana 2 0.0407 0.0621 0.0617
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Echinococcus granulosus serine:threonine protein kinase N2 0.0284 0.034 0.0359
Toxoplasma gondii casein kinase I 0.0412 0.0631 0.3
Trichomonas vaginalis STE family protein kinase 0.0171 0.0084 0.0336
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0437 0.0689 0.3917
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Echinococcus granulosus tyrosine protein kinase HCK 0.0458 0.0736 0.0782
Loa Loa (eye worm) TK/ALK protein kinase 0.1763 0.3709 0.4134
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi ephrin receptor 1 precursor 0.0271 0.031 0.0343
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0346 0.0481 0.0536
Onchocerca volvulus 0.0171 0.0084 0.0153
Onchocerca volvulus 0.1037 0.2056 0.4637
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0588 0.1033 0.1151
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi Protein kinase domain containing protein 0.0643 0.1158 0.1289
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Onchocerca volvulus 0.0184 0.0114 0.0221
Loa Loa (eye worm) TK/ROR protein kinase 0.0257 0.0279 0.0311
Loa Loa (eye worm) SH2 domain-containing protein 0.0184 0.0114 0.0126
Loa Loa (eye worm) hypothetical protein 0.035 0.049 0.0546
Schistosoma mansoni diacylglycerol kinase theta 0.0161 0.0061 0.0155
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0171 0.0084 0.008
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0159 0.0057 0.0313
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0332 0.045 0.0477
Brugia malayi Temporarily assigned gene name protein 59 0.0361 0.0515 0.0572
Brugia malayi serine/threonine-protein kinase 6 0.0547 0.0939 0.1045
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.4074 0.897 1
Echinococcus multilocularis unc 13 (munc13) 0.0165 0.007 0.0066
Schistosoma mansoni protein kinase 0.0332 0.045 0.1175
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis Immunoglobulin 0.0342 0.0473 0.0469
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.0937 0.1828 0.4784
Brugia malayi P21-Rho-binding domain containing protein 0.0136 0.0004 0.0002
Plasmodium vivax serine/threonine protein kinase, putative 0.0234 0.0227 0.1855
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.1591 0.4163
Echinococcus granulosus tyrosine protein kinase Srms 0.0795 0.1503 0.1602
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0412 0.0631 0.0703
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0223 0.0202 0.0225
Echinococcus multilocularis serine:threonine protein kinase 0.0392 0.0586 0.0582
Onchocerca volvulus 0.026 0.0286 0.0612
Onchocerca volvulus Serine\/threonine kinase homolog 0.0412 0.0631 0.1397
Loa Loa (eye worm) AUR protein kinase 0.0547 0.0939 0.1046
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0148 0.0031 0.0034
Schistosoma mansoni hypothetical protein 0.029 0.0355 0.0925
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi casein kinase, putative 0.0412 0.0631 0.3538
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0141 0.0015 0.0011
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0171 0.0084 0.008
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0368 0.0532 0.0564
Brugia malayi casein kinase 1, delta 0.0412 0.0631 0.0702
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0159 0.0057 0.0238
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0513 0.0861 0.4199
Schistosoma mansoni vav2 0.0381 0.056 0.1463
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0152 0.0039 0.0043
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0513 0.0861 0.4197
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0392 0.0586 0.0653
Echinococcus granulosus fibroblast growth factor receptor 4 0.1033 0.2045 0.2181
Schistosoma mansoni serine/threonine protein kinase 0.0906 0.1756 0.4595
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0066 0.0248
Brugia malayi Egg laying defective protein 4 0.0347 0.0484 0.0537
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0514 0.0863 0.4165
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0841 0.1608 0.1791
Plasmodium falciparum cGMP-dependent protein kinase 0.0347 0.0484 0.4102
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1365 0.2803 0.3124
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0474 0.0774 0.0862
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0513 0.0861 0.4858
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0641 0.1154 0.1229
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) TK protein kinase 0.1119 0.2241 0.2498
Entamoeba histolytica protein kinase 2, putative 0.0532 0.0904 0.4397
Toxoplasma gondii AGC kinase 0.1001 0.1972 1
Schistosoma mansoni hypothetical protein 0.0171 0.0084 0.0215
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0956 0.1871 0.1995
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Onchocerca volvulus 0.0223 0.0202 0.0422
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0361 0.0515 0.0546
Echinococcus multilocularis raf serine:threonine protein kinase 0.0333 0.0451 0.0447
Echinococcus granulosus roundabout 2 0.0178 0.0099 0.0102
Echinococcus granulosus activated cdc42 kinase 1 0.0521 0.088 0.0936
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0184 0.0114 0.011
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0533 0.2542
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Loa Loa (eye worm) hypothetical protein 0.075 0.1402 0.1563
Echinococcus multilocularis tyrosine protein kinase Abl 0.0827 0.1577 0.1574
Echinococcus granulosus cyclin dependent kinase 19 0.0547 0.0938 0.0998
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0292 0.0358 0.1745
Schistosoma mansoni serine/threonine-protein kinase 0.0566 0.0984 0.2572
Trypanosoma cruzi cdc2-related kinase 1 0.0588 0.1033 0.5843
Leishmania major protein kinase A catalytic subunit isoform 1 0.0513 0.0861 0.4897
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0464 0.0751 0.6439
Schistosoma mansoni hypothetical protein 0.029 0.0355 0.0925
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0321 0.0424 0.2346
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Brugia malayi C-terminal src kinase protein 1 0.0171 0.0084 0.0091
Trypanosoma cruzi polo-like protein kinase, putative 0.0906 0.1756 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Giardia lamblia Kinase, NEK 0.0163 0.0066 0.029
Trypanosoma brucei Pseudokinase, putative 0.0171 0.0084 0.0408
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0342 0.0473 0.1234
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0321 0.0424 0.2405
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi Cell division protein kinase 2 0.0141 0.0015 0.0015
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0641 0.1154 0.1286
Echinococcus multilocularis serine:threonine protein kinase N2 0.0593 0.1045 0.1042
Brugia malayi protein kinase C3,putative 0.0559 0.0966 0.1075
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0171 0.0084 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Echinococcus multilocularis SH2 motif 0.0184 0.0114 0.011
Schistosoma mansoni SH2A 0.0184 0.0114 0.0293
Brugia malayi Prion-like- 0.0148 0.0031 0.0033
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0613 0.1091 0.6206
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni vesicular amine transporter 0.0342 0.0473 0.1234
Brugia malayi Variant SH3 domain containing protein 0.0346 0.0481 0.0534
Trichomonas vaginalis STE family protein kinase 0.0163 0.0066 0.0248
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1373 0.282 0.2818
Echinococcus granulosus neuroglian 0.0428 0.0669 0.071
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.103 0.2039 0.2036
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0771 0.1449 0.1544
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1159 0.2333 0.5268
Trichomonas vaginalis AGC family protein kinase 0.0547 0.0939 0.4536
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0906 0.1756 0.1872
Entamoeba histolytica casein kinase, putative 0.0346 0.0481 0.2328
Schistosoma mansoni hypothetical protein 0.0184 0.0114 0.0293
Brugia malayi Variant SH3 domain containing protein 0.0313 0.0407 0.0451
Schistosoma mansoni cell adhesion molecule 0.0178 0.0099 0.0256
Schistosoma mansoni septate junction protein 0.0148 0.0031 0.0078
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0412 0.0631 0.067
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Brugia malayi P21-Rho-binding domain containing protein 0.0136 0.0004 0.0002
Brugia malayi Protein kinase domain containing protein 0.0474 0.0774 0.0861
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0171 0.0084 0.0093
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0303 0.0383 0.0427
Loa Loa (eye worm) hypothetical protein 0.0372 0.0541 0.0603
Entamoeba histolytica protein kinase, putative 0.0249 0.0261 0.1257
Giardia lamblia Aurora kinase 0.0547 0.0939 0.5305
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0171 0.0084 0.008
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0857
Giardia lamblia Kinase, AGC PKA 0.0513 0.0861 0.4858
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi NIMA-related kinase, putative 0.0159 0.0057 0.0238
Echinococcus multilocularis tyrosine protein kinase otk 0.0148 0.0031 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0241 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0358 0.1683
Loa Loa (eye worm) hypothetical protein 0.0165 0.007 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0532 0.0904 0.7783
Trypanosoma brucei cdc2-related kinase 1 0.0588 0.1033 0.5033
Brugia malayi Doublecortin family protein 0.0383 0.0565 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0643 0.1158 0.129
Loa Loa (eye worm) hypothetical protein 0.0749 0.14 0.156
Brugia malayi protein kinase C II. 0.0759 0.1422 0.1583
Echinococcus granulosus beta-adrenergic receptor kinase 0.0152 0.0039 0.0037
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus multilocularis myosin iiia 0.0404 0.0613 0.0609
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0298 0.0371 0.1643
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0184 0.0114 0.0221
Loa Loa (eye worm) CDC7 protein kinase 0.0369 0.0533 0.0594
Schistosoma mansoni cell adhesion molecule 0.0148 0.0031 0.0078
Brugia malayi Casein kinase II, alpha chain 0.0346 0.0481 0.0534
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0358 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0424 0.1105
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0163 0.0066 0.0321
Entamoeba histolytica hypothetical protein 0.0173 0.0087 0.0407
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0249 0.0261 0.0275
Brugia malayi Fibronectin type III domain containing protein 0.0372 0.0541 0.0601
Echinococcus granulosus protein kinase c epsilon type 0.0759 0.1422 0.1515
Plasmodium falciparum serine/threonine protein kinase KIN 0.0321 0.0424 0.3575
Brugia malayi Protein kinase domain containing protein 0.1365 0.2803 0.3123
Schistosoma mansoni tyrosine kinase 0.1064 0.2116 0.5537
Leishmania major protein kinase, putative 0.0378 0.0553 0.3144
Echinococcus multilocularis epidermal growth factor receptor 0.1235 0.2506 0.2503
Toxoplasma gondii NEK kinase 0.0163 0.0066 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Onchocerca volvulus 0.1269 0.2584 0.5838
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0212 0.0176 0.0196
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0437 0.0689 0.0768
Echinococcus multilocularis tensin 0.0184 0.0114 0.011
Echinococcus multilocularis cyclin dependent kinase 5 0.0588 0.1033 0.1029
Schistosoma mansoni protein kinase 0.0346 0.0481 0.1254
Trypanosoma brucei protein kinase, putative 0.0308 0.0396 0.193
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0159 0.0057 0.0238
Schistosoma mansoni tyrosine kinase 0.1235 0.2506 0.6558
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0643 0.1158 0.6561
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0161 0.0061 0.0068
Brugia malayi Protein kinase domain containing protein 0.0595 0.1048 0.1166
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0718 0.1328 0.1479
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0292 0.0358 0.1968
Entamoeba histolytica protein kinase, putative 0.0458 0.0736 0.3574
Loa Loa (eye worm) hypothetical protein 0.0749 0.14 0.156
Schistosoma mansoni serine/threonine kinase 0.0593 0.1045 0.2733
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Entamoeba histolytica protein kinase, putative 0.1001 0.1972 0.9613
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.103 0.2039 0.2175
Plasmodium falciparum calcium-dependent protein kinase 2 0.0378 0.0553 0.4711
Echinococcus multilocularis mitogen activated protein kinase 14 0.0806 0.1528 0.1525
Schistosoma mansoni protein kinase C 0.0165 0.007 0.018
Trypanosoma brucei aurora B kinase 0.0547 0.0939 0.4576
Loa Loa (eye worm) hypothetical protein 0.0378 0.0553 0.0617
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Echinococcus granulosus serine:threonine protein kinase mig 15 0.075 0.1402 0.1494
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0292 0.0358 0.0399
Brugia malayi WH1 domain containing protein 0.0136 0.0004 0.0002
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0287 0.0348 0.1908
Echinococcus granulosus raf serine:threonine protein kinase 0.0333 0.0451 0.0478
Trypanosoma brucei rac serine-threonine kinase, putative 0.1035 0.2051 1
Loa Loa (eye worm) hypothetical protein 0.1471 0.3044 0.3393
Echinococcus granulosus epidermal growth factor receptor 0.1771 0.3726 0.3977
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Schistosoma mansoni protein kinase 0.0514 0.0864 0.226
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Schistosoma mansoni tyrosine kinase 0.1068 0.2125 0.5561
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0142 0.0016 0.0018
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0795 0.1503 0.8546
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0292 0.0358 0.1968
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Echinococcus granulosus tyrosine protein kinase Src64B 0.0771 0.1449 0.1544
Schistosoma mansoni tyrosine kinase 0.0585 0.1027 0.2685
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Schistosoma mansoni hypothetical protein 0.0136 0.0004 0.0006
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0771 0.1449 0.1445
Loa Loa (eye worm) TK/FER protein kinase 0.0956 0.1871 0.2085
Entamoeba histolytica p21-activated kinase 0.0367 0.053 0.2567
Onchocerca volvulus 0.0171 0.0084 0.0153
Brugia malayi hypothetical protein 0.0171 0.0084 0.0091
Trypanosoma cruzi casein kinase, putative 0.0412 0.0631 0.3538
Trichomonas vaginalis CMGC family protein kinase 0.0641 0.1154 0.5592
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.4246 0.9362 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0806 0.1528 0.1525
Echinococcus granulosus NCK adaptor protein 0.0313 0.0407 0.043
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0159 0.0057 0.0238
Schistosoma mansoni tensin 0.0184 0.0114 0.0293
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0298 0.0371 0.1811
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Schistosoma mansoni diacylglycerol kinase theta 0.0161 0.0061 0.0155
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0378 0.0553 0.4711
Schistosoma mansoni tyrosine kinase 0.032 0.0421 0.1099
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Brugia malayi Tyrosine-protein kinase PR2 0.0171 0.0084 0.0091
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0404 0.0613 0.3432
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Entamoeba histolytica tyrosin kinase, putative 0.0197 0.0142 0.0673
Schistosoma mansoni neuroglian 0.0178 0.0099 0.0256
Schistosoma mansoni tyrosine kinase 0.1529 0.3176 0.8314
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0795 0.1503 0.8557
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Brugia malayi Protein kinase domain containing protein 0.0145 0.0023 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0298 0.0371 0.1795
Giardia lamblia Kinase, CMGC DYRK 0.0298 0.0371 0.2046
Giardia lamblia Kinase, CMGC CK2 0.0346 0.0481 0.2673
Giardia lamblia Kinase, STE STE20 0.0404 0.0613 0.3432
Echinococcus granulosus SH2 domain containing protein 7 0.0184 0.0114 0.0117
Brugia malayi Ras association domain family 1 isoform A 0.0161 0.0061 0.0066
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0937 0.1828 0.1949
Trichomonas vaginalis AGC family protein kinase 0.0513 0.0861 0.4153
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0136 0.0004 0.0004
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0378 0.0553 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0631 0.1648
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0643 0.1158 0.5643
Schistosoma mansoni hypothetical protein 0.0494 0.0818 0.2139
Trypanosoma cruzi cdc2-related kinase 1 0.0588 0.1033 0.5843
Leishmania major protein kinase, putative 0.0171 0.0084 0.0467
Echinococcus granulosus titin 0.024 0.0241 0.0253
Echinococcus granulosus Rac GTPase activating protein 1 0.0161 0.0061 0.0061
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0321 0.0424 0.042
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Brugia malayi cell division control protein 2 homolog 0.0588 0.1033 0.1149
Loa Loa (eye worm) AGC/PKN protein kinase 0.0877 0.1691 0.1885
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0795 0.1503 0.1675
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0276 0.0322 0.0318
Brugia malayi bone morphogenetic protein type 1 receptor 0.0322 0.0428 0.0475
Echinococcus granulosus serine threonine protein kinase nrc 0.0532 0.0904 0.0962
Brugia malayi Fes/CIP4 homology domain containing protein 0.0299 0.0374 0.0415
Loa Loa (eye worm) hypothetical protein 0.0463 0.0749 0.0835
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0167 0.0743
Entamoeba histolytica ankyrin repeat protein 0.0171 0.0084 0.0389
Loa Loa (eye worm) RGC/RGC protein kinase 0.0171 0.0084 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0301 0.0379 0.0422
Onchocerca volvulus Serine\/threonine kinase homolog 0.0906 0.1756 0.3955
Leishmania major serine/threonine kinase-like protein, putative 0.0141 0.0015 0.0077
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0771 0.1449 0.1445
Trichomonas vaginalis protein kinase atn1, putative 0.0171 0.0084 0.0336
Echinococcus granulosus protein kinase c eta type 0.0161 0.0061 0.0061
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0321 0.0424 0.0472
Echinococcus multilocularis 0.0518 0.0874 0.087
Loa Loa (eye worm) TK protein kinase 0.0171 0.0084 0.0093
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0342 0.0473 0.1234
Loa Loa (eye worm) hypothetical protein 0.0178 0.0099 0.011
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Echinococcus multilocularis dual specificity 0.0795 0.1503 0.15
Schistosoma mansoni protein kinase 0.0136 0.0004 0.0006
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0148 0.0031 0.0078
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0493 0.0816 0.0812
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus multilocularis rho associated protein kinase 0.1394 0.2868 0.2865
Loa Loa (eye worm) hypothetical protein 0.0361 0.0515 0.0574
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0163 0.0066 0.029
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0171 0.0084 0.0093
Leishmania major folate/biopterin transporter, putative 0.0159 0.0057 0.0313
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0177 0.0096 0.0099
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0184 0.0114 0.011
Brugia malayi serine/threonine-protein kinase plk-2 0.0906 0.1756 0.1956
Echinococcus multilocularis tyrosine protein kinase HCK 0.0458 0.0736 0.0732
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Onchocerca volvulus 0.0145 0.0023 0.0015
Trypanosoma brucei Flagellum attachment zone protein 20 0.0171 0.0084 0.0408
Loa Loa (eye worm) hypothetical protein 0.067 0.1219 0.1359
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Plasmodium falciparum protein kinase, putative 0.0296 0.0367 0.3082
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0513 0.0861 0.7403
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0141 0.0015 0.0077
Brugia malayi Protein kinase domain containing protein 0.0795 0.1503 0.1674
Echinococcus granulosus suppressor of cytokine signaling 6 0.0184 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0785 0.1481 0.1651
Brugia malayi Protein kinase domain containing protein 0.0638 0.1147 0.1277
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0292 0.0358 0.1968
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0141 0.0015 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Echinococcus granulosus casein kinase I alpha 0.0412 0.0631 0.067
Echinococcus granulosus lachesin 0.0148 0.0031 0.0029
Schistosoma mansoni serine/threonine-protein kinase 0.0566 0.0984 0.2572
Loa Loa (eye worm) TK/FAK protein kinase 0.1831 0.3864 0.4307
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0404 0.0613 0.2974
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Echinococcus granulosus serine:threonine protein kinase 0.0392 0.0586 0.0622
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0346 0.0481 0.0477
Onchocerca volvulus Netrin receptor homolog 0.0149 0.0034 0.0039
Leishmania major hypothetical protein, conserved 0.0171 0.0084 0.0467
Giardia lamblia Kinase, CMGC GSK 0.0641 0.1154 0.654
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1196 0.2417 0.2414
Echinococcus granulosus tyrosine protein kinase csk 0.0171 0.0084 0.0085
Loa Loa (eye worm) hypothetical protein 0.067 0.1219 0.1359
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0593 0.1045 0.1112
Echinococcus granulosus casein kinase i 0.0412 0.0631 0.067
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica PH domain containing protein kinase, putative 0.0547 0.094 0.4573
Trichomonas vaginalis STE family protein kinase 0.0437 0.0689 0.3309
Echinococcus multilocularis casein kinase I alpha 0.0412 0.0631 0.0627
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Loa Loa (eye worm) TK/Met protein kinase 0.0171 0.0084 0.0093
Echinococcus multilocularis rac serine:threonine kinase 0.0566 0.0984 0.098
Loa Loa (eye worm) TK/EPH protein kinase 0.044 0.0695 0.0775
Schistosoma mansoni tyrosine kinase 0.1529 0.3176 0.8314
Echinococcus granulosus nervana 2 0.0407 0.0621 0.0659
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0533 0.2542
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Plasmodium vivax protein kinase, putative 0.021 0.0171 0.1367
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Brugia malayi cytokine inducible SH2-containing protein 5 0.0184 0.0114 0.0125
Echinococcus granulosus tyrosine protein kinase ABL1 0.1252 0.2545 0.2715
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0184 0.0114 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0084 0.0336
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0513 0.0861 0.7403
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0171 0.0084 0.0336
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0378 0.0553 0.055
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Echinococcus multilocularis cyclin dependent kinase 0.0588 0.1033 0.1029
Schistosoma mansoni unc-13 (munc13) 0.0165 0.007 0.018
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Entamoeba histolytica protein kinase domain containing protein 0.0197 0.0142 0.0673
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0163 0.0066 0.029
Echinococcus multilocularis Diacylglycerol kinase theta 0.0161 0.0061 0.0057
Loa Loa (eye worm) hypothetical protein 0.0342 0.0473 0.0527
Echinococcus granulosus cyclin dependent kinase 7 0.0287 0.0347 0.0366
Loa Loa (eye worm) hypothetical protein 0.101 0.1993 0.2221
Onchocerca volvulus 0.0184 0.0114 0.0221
Entamoeba histolytica serine/threonine protein kinase, putative 0.0321 0.0424 0.205
Schistosoma mansoni protein kinase 0.0808 0.1533 0.401
Schistosoma mansoni growth factor receptor-bound protein 0.0313 0.0407 0.106
Schistosoma mansoni serine/threonine protein kinase 0.0395 0.0594 0.155
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0163 0.0066 0.0443
Entamoeba histolytica protein kinase, putative 0.0298 0.0371 0.1795
Trichomonas vaginalis CMGC family protein kinase 0.0588 0.1033 0.4996
Brugia malayi Immunoglobulin I-set domain containing protein 0.024 0.0241 0.0267
Echinococcus multilocularis insulin receptor 0.1529 0.3176 0.3173
Echinococcus multilocularis receptor type guanylyl cyclase 0.0171 0.0084 0.008
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0159 0.0057 0.0276
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1033 0.2045 0.2042
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Entamoeba histolytica protein kinase, putative 0.0309 0.0397 0.1921
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0808 0.1533 0.1634
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis serine:threonine protein kinase 3 0.1333 0.2729 0.2726
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0424 0.1105
Schistosoma mansoni tyrosine kinase 0.0306 0.039 0.1018
Schistosoma mansoni hypothetical protein 0.0161 0.0061 0.0155
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0643 0.1158 0.6561
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Brugia malayi Guanylyl cyclase protein 23 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0188 0.0121 0.0133
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0378 0.0553 0.0587
Echinococcus granulosus signal transduction protein lnk realted 0.0184 0.0114 0.0117
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0178 0.0099 0.0095
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0547 0.0939 0.0999
Entamoeba histolytica protein kinase, putative 0.0159 0.0057 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0347 0.0903
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0249 0.0261 0.0275
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0184 0.0114 0.0221
Trypanosoma brucei cdc2-related kinase 3 0.0588 0.1033 0.5033
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0261 0.068
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.0861 0.225
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0588 0.1033 0.5095
Schistosoma mansoni serine/threonine kinase 0.0611 0.1086 0.284
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus granulosus microtubule associated protein 2 0.0833 0.1591 0.1696
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1034 0.2048 0.2283
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Echinococcus multilocularis mitogen activated protein kinase 11 0.0806 0.1528 0.1525
Trichomonas vaginalis AGC family protein kinase 0.0284 0.0341 0.16
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0378 0.0553 0.0587
Loa Loa (eye worm) AUR protein kinase 0.0547 0.0939 0.1046
Echinococcus multilocularis tyrosine protein kinase csk 0.0171 0.0084 0.008
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1685 0.3531 0.3528
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0853 0.1637 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Onchocerca volvulus 0.0728 0.1351 0.3033
Brugia malayi Stress-activated protein kinase jnk-1 0.1373 0.282 0.3143
Echinococcus granulosus serine:threonine protein kinase 0.0392 0.0586 0.0622
Giardia lamblia Kinase, NEK 0.0464 0.0751 0.4225
Schistosoma mansoni serine/threonine protein kinase 0.0436 0.0687 0.1795
Loa Loa (eye worm) IKK protein kinase 0.2073 0.4415 0.4921
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0057 0.0203
Brugia malayi Pleckstrin Homology Domain 0.0196 0.014 0.0154
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0378 0.0553 0.4711
Brugia malayi hypothetical protein 0.0372 0.0541 0.0601
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0332 0.045 0.0477
Loa Loa (eye worm) SH2 domain-containing protein 0.0184 0.0114 0.0126
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0163 0.0066 0.0062
Brugia malayi serine/threonine protein kinase 6 0.0547 0.0939 0.1045
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Plasmodium falciparum calcium-dependent protein kinase 3 0.0378 0.0553 0.4711
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0806 0.1528 0.87
Onchocerca volvulus 0.0184 0.0114 0.0221
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Echinococcus multilocularis tyrosine protein kinase pr2 0.0171 0.0084 0.008
Echinococcus granulosus SH2 motif 0.0184 0.0114 0.0117
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0171 0.0084 0.0153
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0196 0.014 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Brugia malayi protein-tyrosine kinase 0.0642 0.1156 0.1286
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus granulosus tyrosine protein kinase Lyn 0.0895 0.1732 0.1847
Echinococcus granulosus fch and double sh3 domains protein 2 0.0142 0.0016 0.0013
Schistosoma mansoni tensin-related 0.0184 0.0114 0.0293
Onchocerca volvulus 0.0211 0.0174 0.0357
Entamoeba histolytica protein kinase , putative 0.0547 0.0939 0.4566
Plasmodium falciparum protein kinase, putative 0.0171 0.0084 0.0599
Trypanosoma brucei Casein kinase II 0.0346 0.0481 0.2343
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1159 0.2333 0.2601
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0313 0.0407 0.106
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0412 0.0631 0.0627
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0159 0.0057 0.0238
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0304 0.0387 0.0383
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0066 0.0248
Echinococcus granulosus tyrosine protein kinase Blk 0.0642 0.1156 0.1231
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0404 0.0613 0.3432
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Plasmodium falciparum glycogen synthase kinase 3 0.0641 0.1154 0.9968
Entamoeba histolytica protein kinase, putative 0.0332 0.045 0.218
Echinococcus multilocularis ephrin type A receptor 4 A 0.0382 0.0564 0.056
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1159 0.2333 0.233
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1314 0.2685 0.2993
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0853 0.1637 0.1633
Echinococcus multilocularis dual specificity 0.0298 0.0371 0.0368
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Loa Loa (eye worm) hypothetical protein 0.0292 0.0358 0.0399
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Brugia malayi Protein kinase domain containing protein 0.0356 0.0504 0.0559
Echinococcus multilocularis N chimaerin 0.0346 0.0481 0.0477
Echinococcus granulosus hemicentin 1 0.0148 0.0031 0.0029
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0178 0.0099 0.0102
Entamoeba histolytica cell division protein kinase 2, putative 0.0605 0.107 0.5209
Brugia malayi Protein kinase domain containing protein 0.0356 0.0504 0.0559
Echinococcus granulosus serine:threonine protein kinase NLK 0.0141 0.0015 0.0012
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0437 0.0689 0.3359
Entamoeba histolytica PH domain containing protein kinase, putative 0.0159 0.0057 0.0257
Leishmania major protein kinase, putative 0.0163 0.0066 0.0365
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Entamoeba histolytica PH domain containing protein kinase, putative 0.0547 0.094 0.4573
Leishmania major protein kinase A catalytic subunit 0.0513 0.0861 0.4897
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0547 0.0939 0.8085
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0841 0.1608 0.1714
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0514 0.0864 0.0963
Echinococcus granulosus tyrosine kinase 0.0356 0.0504 0.0534
Trichomonas vaginalis STE family protein kinase 0.0404 0.0613 0.2935
Brugia malayi tRNA modification GTPase TrmE family protein 0.0184 0.0114 0.0125
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0284 0.0341 0.0337
Loa Loa (eye worm) TK/CSK protein kinase 0.0171 0.0084 0.0093
Brugia malayi Protein kinase domain containing protein 0.0677 0.1235 0.1375
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0906 0.1756 1
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0066 0.0248
Echinococcus granulosus dual specificity 0.0298 0.0371 0.0393
Loa Loa (eye worm) CAMK protein kinase 0.024 0.0241 0.0268
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica protein kinase, putative 0.0547 0.0939 0.4566
Trypanosoma cruzi protein kinase, putative 0.0171 0.0084 0.0393
Schistosoma mansoni serine/threonine protein kinase 0.0593 0.1045 0.2733
Schistosoma mansoni serine/threonine protein kinase 0.0759 0.1422 0.372
Trypanosoma cruzi polo-like protein kinase, putative 0.0906 0.1756 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Echinococcus multilocularis serine:threonine protein kinase 38 0.0593 0.1045 0.1042
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni protein kinase 0.134 0.2746 0.7187
Brugia malayi Protein kinase c protein 2 0.0421 0.0651 0.0724
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Entamoeba histolytica protein kinase, putative 0.0261 0.0288 0.1386
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0248 0.0259 0.0273
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0141 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0196 0.014 0.0156
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1559 0.3244 0.3241
Echinococcus multilocularis SH2 motif 0.0184 0.0114 0.011
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni protein kinase 0.0261 0.0288 0.0749
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Echinococcus multilocularis tensin 0.0184 0.0114 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0099 0.0109
Echinococcus granulosus Glutaredoxin protein 5 0.0407 0.0621 0.0659
Plasmodium falciparum serine/threonine protein kinase 0.0234 0.0227 0.1855
Onchocerca volvulus 0.0171 0.0084 0.0153
Echinococcus multilocularis 0.0184 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0356 0.0504 0.0561
Loa Loa (eye worm) AGC/NDR protein kinase 0.0593 0.1045 0.1165
Brugia malayi Protein kinase domain containing protein 0.0356 0.0504 0.0559
Brugia malayi Protein kinase domain containing protein 0.2073 0.4415 0.4921
Giardia lamblia Kinase, NEK 0.0171 0.0084 0.0393
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0404 0.0613 0.2974
Echinococcus granulosus tensin 0.0184 0.0114 0.0117
Echinococcus granulosus cyclin dependent kinase 5 0.0588 0.1033 0.1099
Trypanosoma brucei SNF1-related protein kinases, putative 0.0321 0.0424 0.2065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0176 0.0195
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0171 0.0084 0.0091
Brugia malayi hypothetical protein 0.0356 0.0504 0.0559
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0099 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica PH domain containing protein kinase, putative 0.0159 0.0057 0.0257
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0485 0.0799 0.0849
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0642 0.1156 0.1152
Onchocerca volvulus 0.0171 0.0084 0.0153
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0171 0.0084 0.0336
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Onchocerca volvulus 0.0184 0.0114 0.0221
Echinococcus multilocularis NCK adaptor protein 0.0319 0.0419 0.0415
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0171 0.0084 0.0215
Echinococcus multilocularis cyclin dependent kinase 9 0.0236 0.0232 0.0228
Echinococcus multilocularis casein kinase I alpha 0.0412 0.0631 0.0627
Schistosoma mansoni adapter molecule crk 0.0313 0.0407 0.106
Echinococcus multilocularis Rac GTPase activating protein 1 0.0161 0.0061 0.0057
Echinococcus multilocularis transfer RNA-Thr 0.0521 0.088 0.0876
Schistosoma mansoni serine/threonine protein kinase 0.0682 0.1247 0.3262
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Loa Loa (eye worm) TK protein kinase 0.0458 0.0736 0.082
Schistosoma mansoni protein kinase 0.0332 0.045 0.1175
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0643 0.1158 0.5747
Giardia lamblia Protein 21.1 0.0171 0.0084 0.0393
Schistosoma mansoni tyrosine kinase 0.0401 0.0607 0.1585
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0249 0.0261 0.0257
Toxoplasma gondii CMGC kinase, CK2 family 0.0346 0.0481 0.2214
Plasmodium vivax serine/threonine kinase-1, putative 0.0643 0.1158 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0382 0.0564 0.0598
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0007 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) TK protein kinase 0.0171 0.0084 0.0093
Onchocerca volvulus 0.0361 0.0515 0.1134
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0184 0.0114 0.011
Echinococcus granulosus c-Jun N-terminal kinases 0.1373 0.282 0.301
Trichomonas vaginalis STE family protein kinase 0.0464 0.0751 0.3612
Echinococcus multilocularis hypothetical protein 0.029 0.0355 0.0351
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0378 0.0553 0.0617
Echinococcus multilocularis protein kinase c eta type 0.0161 0.0061 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0175 0.0092 0.0375
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Plasmodium vivax calcium-dependent protein kinase, putative 0.0378 0.0553 0.4711
Onchocerca volvulus 0.0287 0.0348 0.0753
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0298 0.0371 0.0414
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1196 0.2417 0.2578
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0178 0.0099 0.0256
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica receptor protein kinase, putative 0.0171 0.0084 0.0389
Schistosoma mansoni hypothetical protein 0.0136 0.0004 0.0006
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0656 0.1188 0.1324
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.0678 0.3253
Schistosoma mansoni tyrosine kinase 0.1033 0.2045 0.5352
Brugia malayi Protein kinase domain containing protein 0.0547 0.0938 0.1044
Onchocerca volvulus 0.0171 0.0084 0.0153
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1178 0.2375 0.2648
Loa Loa (eye worm) serine/threonine protein kinase 0.0171 0.0084 0.0093
Schistosoma mansoni serine/threonine RGC 0.0171 0.0084 0.0215
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0593 0.1045 0.1112
Schistosoma mansoni tyrosine kinase 0.0771 0.1449 0.379
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0485 0.0799 0.0795
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0916
Loa Loa (eye worm) hypothetical protein 0.0321 0.0424 0.0472
Schistosoma mansoni titin 0.024 0.0241 0.0627
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1373 0.282 0.3144
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1252 0.2545 0.2542
Onchocerca volvulus 0.0532 0.0904 0.2018
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Schistosoma mansoni growth factor receptor-bound protein 0.0319 0.0419 0.1093
Loa Loa (eye worm) TK/DDR protein kinase 0.0171 0.0084 0.0093
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0378 0.0553 0.4711
Brugia malayi STE20-like kinase MST 0.1333 0.2729 0.3041
Brugia malayi Temporarily assigned gene name protein 59 0.0425 0.0661 0.0735
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0916
Loa Loa (eye worm) hypothetical protein 0.0372 0.0541 0.0603
Echinococcus granulosus mitogen activated protein kinase 3 0.0292 0.0358 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0889 0.1719 0.4498
Brugia malayi Receptor family ligand binding region containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Echinococcus granulosus NDR protein kinase 0.0593 0.1045 0.1112
Trypanosoma cruzi casein kinase, putative 0.0412 0.0631 0.3538
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0257 0.0279 0.0276
Loa Loa (eye worm) hypothetical protein 0.0532 0.0904 0.1008
Entamoeba histolytica tyrosin kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0177 0.0096 0.0092
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0906 0.1756 0.1957
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0484 0.1263
Loa Loa (eye worm) RGC/RGC protein kinase 0.0171 0.0084 0.0093
Echinococcus granulosus expressed conserved protein 0.0184 0.0114 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0682 0.1247 0.3262
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.0678 0.3253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Brugia malayi Protein kinase domain containing protein 0.0254 0.0271 0.03
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0682 0.1247 0.1243
Brugia malayi p70 ribosomal S6 kinase beta 0.1001 0.1972 0.2197
Schistosoma mansoni tensin 0.0184 0.0114 0.0293
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0361 0.0515 0.0511
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0309 0.0397 0.1921
Loa Loa (eye worm) AUR protein kinase 0.0547 0.0939 0.1046
Brugia malayi Tensin 0.0184 0.0114 0.0125
Loa Loa (eye worm) hypothetical protein 0.0344 0.0477 0.0531
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0346 0.0481 0.051
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) SH2 domain-containing protein 0.0184 0.0114 0.0126
Trichomonas vaginalis CK1 family protein kinase 0.0412 0.0631 0.3025
Echinococcus multilocularis casein kinase I delta 0.0412 0.0631 0.0627
Echinococcus granulosus suppressor of cytokine signaling 7 0.0184 0.0114 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi casein kinase, putative 0.0412 0.0631 0.3538
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0184 0.0114 0.0126
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Entamoeba histolytica hypothetical protein 0.0173 0.0087 0.0407
Loa Loa (eye worm) hypothetical protein 0.0521 0.088 0.0981
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Echinococcus granulosus plexin a4 0.0138 0.0009 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0173 0.0449
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0084 0.0215
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Brugia malayi cyclin-dependent kinase 7 homolog 0.0303 0.0384 0.0427
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni nck2/grb4 0.0313 0.0407 0.106
Loa Loa (eye worm) raf kinase 0.0161 0.0061 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Giardia lamblia Kinase, CMGC CDK 0.0588 0.1033 0.5843
Echinococcus multilocularis protein kinase 0.0171 0.0084 0.008
Echinococcus multilocularis c src tyrosine kinase 0.0484 0.0797 0.0793
Giardia lamblia Kinase, NEK 0.0464 0.0751 0.4225
Echinococcus granulosus aurora kinase A 0.0547 0.0939 0.0999
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0057 0.0203
Brugia malayi hypothetical protein 0.0196 0.014 0.0154
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.1591 0.1588
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0937 0.1828 0.1825
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.014 0.0362
Echinococcus granulosus activated cdc42 kinase 1 0.0521 0.088 0.0936
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Brugia malayi Protein kinase domain 0.0332 0.045 0.05
Onchocerca volvulus 0.0184 0.0114 0.0221
Schistosoma mansoni protein kinase 0.1196 0.2417 0.6326
Entamoeba histolytica hypothetical protein 0.0159 0.0057 0.0257
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0321 0.0424 0.2346
Echinococcus multilocularis CDC7 cell division cycle 7 0.0369 0.0533 0.0529
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0588 0.1033 0.1151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0372 0.0541 0.0601
Brugia malayi cyclin-dependent kinase 9 0.022 0.0194 0.0214
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0547 0.0939 0.0935
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0084 0.0336
Plasmodium falciparum calcium-dependent protein kinase 4 0.0378 0.0553 0.4711
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Onchocerca volvulus 0.0356 0.0504 0.1108
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0184 0.0114 0.0293
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0795 0.1503 0.8546
Entamoeba histolytica protein kinase, putative 0.0249 0.0261 0.1257
Echinococcus granulosus mitogen activated protein kinase 14 0.0806 0.1528 0.1629
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1134 0.2277 0.2274
Brugia malayi Furin-like cysteine rich region family protein 0.1771 0.3726 0.4152
Echinococcus granulosus casein kinase ii subunit alpha 0.0346 0.0481 0.0509
Plasmodium vivax tyrosine kinase-like protein, putative 0.0171 0.0084 0.0599
Plasmodium falciparum tyrosine kinase-like protein 0.0171 0.0084 0.0599
Schistosoma mansoni protein kinase 0.134 0.2746 0.7187
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0204 0.0159 0.0704
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0171 0.0084 0.008
Trypanosoma cruzi p21-activated kinase 3, putative 0.0196 0.014 0.0716
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1048 0.2079 0.2317
Echinococcus multilocularis FL cytokine receptor 0.0171 0.0084 0.008
Entamoeba histolytica protein kinase, putative 0.0159 0.0057 0.0257
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0513 0.0861 0.0958
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0547 0.0939 0.4566
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0159 0.0057 0.0276
Echinococcus multilocularis protein kinase c epsilon type 0.0759 0.1422 0.1418
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Brugia malayi diacylglycerol kinase 0.0161 0.0061 0.0066
Plasmodium falciparum protein kinase, putative 0.0171 0.0084 0.0599
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0163 0.0066 0.029
Echinococcus multilocularis protein kinase c iota type 0.1028 0.2034 0.2031
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.1033 0.27
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0171 0.0084 0.0215
Echinococcus multilocularis epidermal growth factor receptor 0.1771 0.3726 0.3723
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0332 0.045 0.0446
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0857
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0347 0.0484 0.048
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0227 0.0591
Echinococcus granulosus tyrosine protein kinase Fyn 0.0771 0.1449 0.1544
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0476 0.0778 0.0774
Trypanosoma cruzi cdc2-related kinase 3 0.0588 0.1033 0.5843
Toxoplasma gondii AGC kinase 0.0513 0.0861 0.4199
Echinococcus granulosus protein tyrosine kinase 0.1812 0.382 0.4077
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0321 0.0424 0.2065
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0322 0.0428 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0424 0.1105
Schistosoma mansoni ephrin receptor 0.0201 0.0152 0.0392
Toxoplasma gondii protein kinase domain-containing protein 0.0171 0.0084 0.0141
Schistosoma mansoni ste20-related kinase 0.1054 0.2094 0.5479
Trichomonas vaginalis CMGC family protein kinase 0.0643 0.1158 0.561
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0361 0.0515 0.1344
Schistosoma mansoni tyrosine kinase 0.0484 0.0797 0.2082
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0818 0.0815
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica diacylglycerol kinase, putative 0.0161 0.0061 0.0278
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Trypanosoma brucei polo-like protein kinase 0.0906 0.1756 0.8561
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.1314 0.2685 0.7028
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Echinococcus granulosus casein kinase I alpha 0.0412 0.0631 0.067
Echinococcus granulosus Vam6:Vps39 protein 0.0361 0.0515 0.0546
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0532 0.0904 0.0901
Schistosoma mansoni tyrosine kinase 0.0308 0.0394 0.1027
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0163 0.0066 0.0443
Brugia malayi hypothetical protein 0.0184 0.0114 0.0125
Echinococcus granulosus serine:threonine protein kinase 3 0.1333 0.2729 0.2912
Plasmodium vivax glycogen synthase kinase 3, putative 0.0641 0.1154 0.9968
Echinococcus multilocularis tyrosine protein kinase 0.0429 0.0671 0.0668
Schistosoma mansoni tyrosine kinase 0.1064 0.2116 0.5537
Entamoeba histolytica protein kinase domain containing protein 0.0296 0.0367 0.1775
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0806 0.1529 0.163
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0395 0.0594 0.0662
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0039 0.0098
Echinococcus multilocularis hemicentin 1 0.0148 0.0031 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis AGC family protein kinase 0.0464 0.0751 0.3612
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0169 0.0079 0.0314
Trypanosoma cruzi protein kinase, putative 0.0171 0.0084 0.0393
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0368 0.0532 0.0528
Brugia malayi Protein kinase domain containing protein 0.1196 0.2417 0.2693
Onchocerca volvulus 0.0356 0.0504 0.1108
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus granulosus dual specificity 0.0795 0.1503 0.1602
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0171 0.0084 0.0408
Brugia malayi plexin A 0.0138 0.0009 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Brugia malayi Protein kinase domain containing protein 0.1764 0.371 0.4134
Echinococcus granulosus tyrosine kinase 0.0171 0.0084 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Schistosoma mansoni rap gtpase-activating protein 0.0361 0.0515 0.1344
Brugia malayi hypothetical protein 0.0937 0.1828 0.2036
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0178 0.0099 0.0095
Onchocerca volvulus 0.015 0.0036 0.0045
Giardia lamblia Kinase, CMGC CLK 0.0643 0.1158 0.6561
Entamoeba histolytica cysteine surface protein, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0513 0.0861 0.4858
Schistosoma mansoni protein kinase 0.0276 0.0322 0.0838
Entamoeba histolytica hypothetical protein, conserved 0.0171 0.0084 0.0389
Leishmania major protein kinase, putative 0.0159 0.0057 0.0313
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0171 0.0084 0.0085
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0532 0.0904 0.5107
Schistosoma mansoni hypothetical protein 0.0184 0.0114 0.0293
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0234 0.0227 0.0253
Echinococcus multilocularis kinase suppressor of Ras 1 0.0171 0.0084 0.008
Onchocerca volvulus 0.0165 0.007 0.0123
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0407 0.0621 0.0617
Brugia malayi RhoGEF domain containing protein 0.0161 0.0061 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.0639 0.1668
Echinococcus granulosus tyrosine protein kinase shark 0.0585 0.1027 0.1093
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0296 0.0367 0.1622
Brugia malayi Protein kinase domain containing protein 0.0677 0.1236 0.1376
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.1048 0.5072
Brugia malayi STAT protein, DNA binding domain containing protein 0.0184 0.0114 0.0125
Loa Loa (eye worm) plexin A 0.0138 0.0009 0.001
Echinococcus granulosus tyrosine protein kinase Src42A 0.0771 0.1449 0.1544
Onchocerca volvulus 0.0171 0.0084 0.0153
Entamoeba histolytica hypothetical protein 0.0172 0.0086 0.04
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0171 0.0084 0.0215
Echinococcus granulosus cGMP dependent protein kinase 1 0.0347 0.0484 0.0513
Entamoeba histolytica serine/threonine protein kinase, putative 0.0163 0.0066 0.0302
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0184 0.0114 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi casein kinase I 0.0412 0.0631 0.0702
Echinococcus granulosus calcium activated potassium channel 0.0415 0.0639 0.0678
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0593 0.1045 0.1042
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.024 0.0241 0.0268
Loa Loa (eye worm) hypothetical protein 0.0372 0.0541 0.0603
Schistosoma mansoni shc transforming protein 0.0184 0.0114 0.0293
Echinococcus granulosus tyrosine protein kinase csk 0.0171 0.0084 0.0085
Echinococcus granulosus casein kinase I gamma 0.0452 0.0724 0.0769
Mycobacterium ulcerans hypothetical protein 0.0222 0.02 0.5
Loa Loa (eye worm) hypothetical protein 0.0361 0.0515 0.0574
Trichomonas vaginalis CAMK family protein kinase 0.0378 0.0553 0.2643
Echinococcus granulosus titin 0.024 0.0241 0.0253
Entamoeba histolytica protein kinase, putative 0.0378 0.0553 0.2683
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0759 0.1422 0.1585
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.0639 0.1668
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0641 0.1154 0.3018
Schistosoma mansoni protein kinase 0.0171 0.0084 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis neuroglian 0.0178 0.0099 0.0095
Plasmodium vivax unspecified product 0.0346 0.0481 0.4074
Schistosoma mansoni serine/threonine protein kinase 0.0835 0.1596 0.4175
Echinococcus multilocularis SH2 domain containing protein 7 0.0184 0.0114 0.011
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0173 0.0087 0.0407
Toxoplasma gondii NEK kinase 0.0163 0.0066 0.0048
Trypanosoma brucei protein kinase, putative 0.0296 0.0367 0.1791
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0906 0.1756 0.855
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus granulosus tyrosine kinase 0.0642 0.1156 0.1231
Echinococcus granulosus casein kinase I alpha 0.0412 0.0631 0.067
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Loa Loa (eye worm) hypothetical protein 0.0392 0.0586 0.0653
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0346 0.0481 0.0536
Brugia malayi Protein kinase domain containing protein 0.0392 0.0586 0.0651
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Loa Loa (eye worm) hypothetical protein 0.029 0.0355 0.0395
Echinococcus granulosus intersectin 2 0.0138 0.0009 0.0005
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0234 0.0227 0.0891
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0196 0.014 0.0716
Loa Loa (eye worm) hypothetical protein 0.0219 0.0193 0.0215
Echinococcus granulosus tyrosine protein kinase 0.0429 0.0671 0.0713
Echinococcus multilocularis activin receptor type 0.1068 0.2126 0.2122
Schistosoma mansoni serine/threonine protein kinase 0.1538 0.3195 0.8365
Loa Loa (eye worm) hypothetical protein 0.1365 0.2803 0.3124
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni tensin-related 0.0184 0.0114 0.0293
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0163 0.0066 0.0168
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.022 0.0194 0.0216
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0547 0.0939 0.4566
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0171 0.0084 0.0085
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0412 0.0631 0.0703
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Schistosoma mansoni nephrin 0.0458 0.0737 0.1925
Echinococcus granulosus kinase suppressor of Ras 1 0.0171 0.0084 0.0085
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0682 0.1247 0.1328
Onchocerca volvulus 0.0171 0.0084 0.0153
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Echinococcus multilocularis hemicentin 1 0.0148 0.0031 0.0027
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Echinococcus granulosus cGMP dependent protein kinase 1 0.0347 0.0484 0.0513
Echinococcus multilocularis tyrosine protein kinase csk 0.0171 0.0084 0.008
Brugia malayi Protein kinase domain containing protein 0.0593 0.1045 0.1163
Echinococcus multilocularis protein kinase 0.0171 0.0084 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0593 0.1045 0.2733
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0159 0.0057 0.0238
Brugia malayi Sex muscle abnormal protein 5 0.0313 0.0407 0.0451
Loa Loa (eye worm) hypothetical protein 0.0547 0.0938 0.1046
Loa Loa (eye worm) RGC/RGC protein kinase 0.0171 0.0084 0.0093
Leishmania major protein kinase, putative 0.0643 0.1158 0.6588
Loa Loa (eye worm) RasGEF domain-containing protein 0.0161 0.0061 0.0068
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0378 0.0553 0.0617
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis tyrosine protein kinase csk 0.0171 0.0084 0.008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0178 0.0099 0.011
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0171 0.0084 0.0093
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0916
Brugia malayi Protein kinase domain containing protein 0.0141 0.0015 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0066 0.0248
Echinococcus multilocularis serine threonine protein kinase 0.0728 0.1352 0.1348
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0136 0.0004 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.1503 0.3932
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0171 0.0084 0.0389
Brugia malayi Protein kinase domain containing protein 0.0369 0.0533 0.0592
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Loa Loa (eye worm) TK protein kinase 0.0642 0.1156 0.1288
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0532 0.0904 0.0962
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis SHC transforming protein 3 0.0184 0.0114 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0853 0.1637 0.7974
Echinococcus granulosus c src tyrosine kinase 0.0484 0.0797 0.0847
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Brugia malayi Protein kinase domain containing protein 0.0356 0.0504 0.0559
Trypanosoma brucei protein kinase, putative 0.0641 0.1154 0.5625
Giardia lamblia Kinase, NEK 0.0171 0.0084 0.0393
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0889 0.1719 0.1716
Loa Loa (eye worm) hypothetical protein 0.0196 0.014 0.0156
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Loa Loa (eye worm) TK/ABL protein kinase 0.1252 0.2545 0.2836
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0429 0.0671 0.0747
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0378 0.0553 0.2593
Schistosoma mansoni titin 0.0148 0.0031 0.0078
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0249 0.0261 0.0257
Entamoeba histolytica protein kinase, putative 0.0593 0.1045 0.5085
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.0639 0.1668
Loa Loa (eye worm) hypothetical protein 0.0171 0.0084 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Brugia malayi Protein kinase domain containing protein 0.0452 0.0724 0.0805
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni protein kinase 0.0474 0.0774 0.2022
Plasmodium vivax protein kinase Crk2 0.0588 0.1033 0.8906
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0956 0.1871 0.1868
Onchocerca volvulus 0.0369 0.0533 0.1174
Giardia lamblia Kinase, CMGC CDK 0.0588 0.1033 0.5843
Echinococcus multilocularis plexin a4 0.0138 0.0009 0.0005
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0159 0.0057 0.0276
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0806 0.1528 0.1703
Entamoeba histolytica tyrosin kinase, putative 0.0171 0.0084 0.0389
Echinococcus granulosus contactin 0.0178 0.0099 0.0102
Schistosoma mansoni tyrosine kinase 0.1562 0.325 0.8509
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0641 0.1154 0.654
Echinococcus multilocularis dual specificity 0.0298 0.0371 0.0368
Entamoeba histolytica hypothetical protein 0.0161 0.0061 0.0278
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0361 0.0515 0.1344
Trichomonas vaginalis STE family protein kinase 0.0332 0.045 0.2136
Echinococcus multilocularis casein kinase I alpha 0.0412 0.0631 0.0627
Echinococcus granulosus protein kinase C gamma type 0.0728 0.1352 0.144
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis protein tyrosine kinase 0.1812 0.382 0.3817
Loa Loa (eye worm) hypothetical protein 0.0306 0.039 0.0435
Trichomonas vaginalis STE family protein kinase 0.0437 0.0689 0.3309
Echinococcus multilocularis intersectin 2 0.0138 0.0009 0.0005
Onchocerca volvulus 0.0641 0.1154 0.2586
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0084 0.0336
Entamoeba histolytica protein kinase, putative 0.0641 0.1154 0.5616
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0407 0.0621 0.0659
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.0939 0.2454
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Trichomonas vaginalis AGC family protein kinase 0.061 0.1083 0.5244
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0031 0.0033
Brugia malayi serine/threonine kinase 12 0.0547 0.0939 0.1045
Schistosoma mansoni roundabout 0.0148 0.0031 0.0078
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0313 0.0407 0.0453
Echinococcus granulosus tyrosine protein kinase pr2 0.0171 0.0084 0.0085
Echinococcus granulosus expressed protein 0.0234 0.0227 0.0239
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0361 0.0515 0.2871
Leishmania major casein kinase II, putative 0.0346 0.0481 0.273
Loa Loa (eye worm) STAT protein 0.0184 0.0114 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.1394 0.2868 0.7507
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0412 0.0631 0.0703
Brugia malayi Raf kinase 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0412 0.0631 0.0701
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0771 0.1449 0.1445
Loa Loa (eye worm) hypothetical protein 0.0211 0.0174 0.0193
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0368 0.0532 0.0593
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0347 0.0484 0.048
Schistosoma mansoni protein kinase 0.0808 0.1533 0.401
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0163 0.0066 0.0321
Entamoeba histolytica PH domain containing protein kinase, putative 0.0566 0.0984 0.4785
Leishmania major serine/threonine-protein kinase a, putative 0.0159 0.0057 0.0313
Trypanosoma brucei protein kinase, putative 0.0159 0.0057 0.0276
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Brugia malayi Protein kinase domain containing protein 0.0356 0.0504 0.0559
Loa Loa (eye worm) hypothetical protein 0.0196 0.014 0.0156
Plasmodium falciparum calcium-dependent protein kinase 1 0.0378 0.0553 0.4711
Loa Loa (eye worm) TK/RYK protein kinase 0.0171 0.0084 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Echinococcus multilocularis roundabout 2 0.052 0.0879 0.0875
Loa Loa (eye worm) TK protein kinase 0.0171 0.0084 0.0093
Giardia lamblia Kinase, AGC AKT 0.0579 0.1011 0.5721
Brugia malayi Protein kinase domain containing protein 0.0284 0.0341 0.0378
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0643 0.1158 0.5643
Onchocerca volvulus 0.0693 0.1271 0.2853
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0259 0.0284 0.0316
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1365 0.2803 0.3124
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0347 0.0484 0.223
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0159 0.0057 0.0276
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0771 0.1449 0.1445
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0346 0.0481 0.1255
Echinococcus multilocularis expressed protein 0.0234 0.0227 0.0223
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0022 0.0024
Echinococcus granulosus dual specificity mitogen activated protein 0.0437 0.0689 0.0732
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0378 0.0553 0.055
Echinococcus granulosus serine:threonine kinase SAD 1 0.0321 0.0424 0.0448
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0405 0.0615 0.0653
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0292 0.0358 0.203
Echinococcus multilocularis natriuretic peptide receptor 1 0.0171 0.0084 0.008
Trichomonas vaginalis AGC family protein kinase 0.1035 0.2051 1
Schistosoma mansoni suppressor of cytokine signaling 0.0184 0.0114 0.0293
Entamoeba histolytica protein kinase domain containing protein 0.0346 0.0481 0.2328
Plasmodium falciparum NIMA related kinase 2 0.0163 0.0066 0.0443
Echinococcus granulosus retinal guanylyl cyclase 2 0.0171 0.0084 0.0085
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0841 0.1608 0.1605
Schistosoma mansoni serine/threonine protein kinase 0.1373 0.282 0.7383
Echinococcus multilocularis casein kinase I delta 0.0412 0.0631 0.0627
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0361 0.0515 0.2511
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1048 0.2079 0.2217
Schistosoma mansoni unc-13 (munc13) 0.0165 0.007 0.018
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1033 0.2045 0.2042
Echinococcus multilocularis casein kinase ii subunit alpha 0.0346 0.0481 0.0477
Echinococcus granulosus roundabout 2 0.052 0.0879 0.0935
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0178 0.0099 0.0095
Loa Loa (eye worm) hypothetical protein 0.0513 0.0861 0.0959
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0234 0.0227 0.1108
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0358 0.1683
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0806 0.1529 0.1526
Loa Loa (eye worm) protein kinase domain-containing protein 0.0452 0.0724 0.0806
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0287 0.0347 0.0386
Echinococcus multilocularis serine:threonine protein kinase N2 0.0284 0.034 0.0336
Entamoeba histolytica protein kinase, putative 0.0382 0.0563 0.2729
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0588 0.1033 0.5875
Echinococcus granulosus cyclin dependent kinase 9 0.022 0.0194 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0631 0.1649
Entamoeba histolytica hypothetical protein 0.0163 0.0066 0.0303
Echinococcus multilocularis protein KINase family member (kin 25) 0.0306 0.039 0.0386
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0513 0.0861 0.0857
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0223 0.0202 0.0225
Plasmodium falciparum serine/threonine protein kinase, putative 0.0547 0.0939 0.8085
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0196 0.014 0.0156
Loa Loa (eye worm) hypothetical protein 0.0313 0.0407 0.0453
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0171 0.0084 0.0091
Echinococcus multilocularis integrin linked protein kinase 0.0171 0.0084 0.008
Loa Loa (eye worm) TK protein kinase 0.0429 0.0671 0.0748
Brugia malayi Protein kinase domain containing protein 0.0171 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0749 0.14 0.156
Plasmodium falciparum tyrosine kinase-like protein 0.0171 0.0084 0.0599
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0171 0.0084 0.0215
Entamoeba histolytica protein kinase, putative 0.0171 0.0084 0.0389
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0795 0.1503 0.7327
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0388 0.0577 0.0573
Schistosoma mansoni protein kinase 0.0141 0.0015 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0171 0.0084 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0922 0.1794 0.8736
Loa Loa (eye worm) protein kinase domain-containing protein 0.0171 0.0084 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0171 0.0084 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0513 0.0861 0.4197
Loa Loa (eye worm) TK/ACK protein kinase 0.0171 0.0084 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0015 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0392 0.0586 0.2801
Entamoeba histolytica serine/threonine kinase, putative 0.0171 0.0084 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0194 0.0503
Brugia malayi putative serine/threonine kinase SADA gamma 0.0321 0.0424 0.047
Echinococcus multilocularis protein kinase shaggy 0.0641 0.1154 0.115
Plasmodium falciparum protein serine/threonine kinase-1 0.0643 0.1158 1
Schistosoma mansoni hypothetical protein 0.0136 0.0004 0.0006
Brugia malayi Protein kinase domain containing protein 0.4074 0.897 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0513 0.0861 0.0959
Echinococcus multilocularis calcium dependent protein kinase 0.0253 0.027 0.0266
Schistosoma mansoni protein kinase 0.0412 0.0631 0.1649
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0079 0.0314
Echinococcus multilocularis roundabout 2 0.0178 0.0099 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0066 0.0168
Schistosoma mansoni ephrin receptor 0.0382 0.0564 0.1471
Schistosoma mansoni protein kinase 0.0547 0.0939 0.2454
Brugia malayi Hr1 repeat family protein 0.0877 0.1691 0.1884
Echinococcus multilocularis casein kinase I gamma 0.0452 0.0724 0.072
Schistosoma mansoni tyrosine kinase 0.0771 0.1449 0.379
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0641 0.1154 0.115
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Entamoeba histolytica protein kinase, putative 0.0149 0.0033 0.0142
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0513 0.0861 0.4197
Schistosoma mansoni kinase 0.022 0.0194 0.0503
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0332 0.045 0.0477
Echinococcus granulosus dual specificity 0.0298 0.0371 0.0393
Trypanosoma cruzi NIMA-related kinase, putative 0.0163 0.0066 0.029
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0141 0.0015 0.0075
Echinococcus granulosus retinal guanylyl cyclase 2 0.0171 0.0084 0.0085
Brugia malayi SH2 domain containing protein 0.0184 0.0114 0.0125
Echinococcus granulosus defective proboscis extension response 0.0342 0.0473 0.0501
Brugia malayi Cam kinase protein 1 0.0378 0.0553 0.0615
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1685 0.3531 0.3768
Loa Loa (eye worm) gastrulation defective protein 1 0.0422 0.0655 0.0729
Echinococcus granulosus protein kinase c iota type 0.1028 0.2034 0.2169
Echinococcus multilocularis serine:threonine protein kinase 0.0392 0.0586 0.0582
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Echinococcus granulosus Immunoglobulin 0.0342 0.0473 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0347 0.0903
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.0806 0.1529 0.4001
Entamoeba histolytica protein kinase, putative 0.0547 0.0939 0.4566
Schistosoma mansoni tensin 0.0184 0.0114 0.0293
Echinococcus granulosus mitogen activated protein kinase 0.0292 0.0358 0.0378
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0682 0.1247 0.1328
Entamoeba histolytica protein kinase, putative 0.1035 0.2051 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0031 0.0035
Trichomonas vaginalis STE family protein kinase 0.0332 0.045 0.2136
Entamoeba histolytica protein kinase, putative 0.1035 0.2051 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0159 0.0057 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0196 0.014 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0677 0.1235 0.3231
Trichomonas vaginalis AGC family protein kinase 0.0301 0.0379 0.1786
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Brugia malayi Immunoglobulin I-set domain containing protein 0.1613 0.3367 0.3752
Giardia lamblia Kinase, STE STE20 0.0332 0.045 0.2498
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Echinococcus multilocularis serine:threonine protein kinase N2 0.0877 0.1691 0.1688
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0171 0.0084 0.0336
Onchocerca volvulus 0.0356 0.0504 0.1108
Echinococcus granulosus cyclin dependent kinase 9 0.0236 0.0232 0.0243
Entamoeba histolytica protein kinase domain containing protein 0.022 0.0194 0.0927
Echinococcus multilocularis dual specificity mitogen activated protein 0.0437 0.0689 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0371 0.1749
Trichomonas vaginalis AGC family protein kinase 0.0638 0.1147 0.5558
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0171 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0728 0.1351 0.1505
Trichomonas vaginalis AGC family protein kinase 0.0204 0.0159 0.0704
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0022 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Loa Loa (eye worm) hypothetical protein 0.0184 0.0114 0.0126
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0513 0.0861 0.4858
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0771 0.1449 0.1445
Echinococcus granulosus SH2 domain containing adapter protein F 0.0184 0.0114 0.0117
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0163 0.0066 0.0066
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0378 0.0553 0.0615
Entamoeba histolytica tyrosine kinase, putative 0.0171 0.0084 0.0389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0378 0.0553 0.055
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0159 0.0057 0.0238
Entamoeba histolytica hypothetical protein 0.0171 0.0084 0.0389
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0841 0.1608 0.1793
Entamoeba histolytica protein kinase domain containing protein 0.0641 0.1154 0.5616
Schistosoma mansoni serine/threonine protein kinase 0.0889 0.1719 0.4498
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0533 0.2542
Schistosoma mansoni protein kinase 0.0875 0.1686 0.4411
Echinococcus multilocularis SH2 motif 0.0184 0.0114 0.011
Trypanosoma brucei NIMA-related protein kinase 0.0163 0.0066 0.0321
Trichomonas vaginalis CK1 family protein kinase 0.0412 0.0631 0.3025
Toxoplasma gondii NEK kinase 0.0163 0.0066 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0643 0.1158 0.3027
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0184 0.0114 0.0126
Entamoeba histolytica protein kinase domain containing protein 0.0641 0.1154 0.5616
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Trichomonas vaginalis CAMK family protein kinase 0.0304 0.0387 0.1824
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0464 0.0751 0.3624
Loa Loa (eye worm) TK/FER protein kinase 0.0356 0.0504 0.0561
Trypanosoma cruzi casein kinase, putative 0.0412 0.0631 0.3538
Schistosoma mansoni vam6/vps39 related 0.0361 0.0515 0.1344
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0306 0.039 0.0413
Brugia malayi Protein kinase domain containing protein 0.1831 0.3864 0.4306
Entamoeba histolytica protein kinase, putative 0.0795 0.1503 0.7321
Echinococcus granulosus N chimaerin 0.0346 0.0481 0.051
Entamoeba histolytica diacylglycerol kinase, putative 0.0161 0.0061 0.0278
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1001 0.1972 0.2198
Loa Loa (eye worm) hypothetical protein 0.0161 0.0061 0.0068
Echinococcus granulosus roundabout 2 0.0178 0.0099 0.0102
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0184 0.0114 0.011
Onchocerca volvulus Tyrosine kinase homolog 0.1295 0.2642 0.5968
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.1033 0.27
Echinococcus granulosus mitogen activated protein kinase 15 0.0141 0.0015 0.0012
Brugia malayi Serine/threonine-protein kinase SULU 0.0937 0.1828 0.2036
Echinococcus multilocularis nervana 2 0.0407 0.0621 0.0617
Leishmania major protein kinase, putative 0.0643 0.1158 0.6588
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0342 0.0473 0.0469
Loa Loa (eye worm) AGC/AKT protein kinase 0.1035 0.2051 0.2287
Giardia lamblia Kinase, CK1 Casein kinase 0.0412 0.0631 0.3538
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0641 0.1154 0.6567
Loa Loa (eye worm) hypothetical protein 0.0405 0.0615 0.0685
Entamoeba histolytica casein kinase, putative 0.0412 0.0631 0.3063
Trichomonas vaginalis CMGC family protein kinase 0.0588 0.1033 0.4996
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0142 0.0016 0.0012
Onchocerca volvulus 0.2073 0.4415 1
Brugia malayi MH2 domain containing protein 0.0144 0.0022 0.0022
Echinococcus granulosus protein kinase shaggy 0.0641 0.1154 0.1229
Schistosoma mansoni tyrosine kinase 0.0171 0.0084 0.0215
Loa Loa (eye worm) hypothetical protein 0.0361 0.0515 0.0574
Loa Loa (eye worm) hypothetical protein 0.091 0.1767 0.1969
Schistosoma mansoni protein kinase 0.134 0.2746 0.7187
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Echinococcus multilocularis aurora kinase A 0.0547 0.0939 0.0935
Brugia malayi Protein kinase domain containing protein 0.0588 0.1033 0.1149
Schistosoma mansoni serine/threonine protein kinase 0.0378 0.0553 0.1445
Echinococcus multilocularis signal transduction protein lnk realted 0.0184 0.0114 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0424 0.2005
Leishmania major protein kinase, putative 0.0296 0.0367 0.2084
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0771 0.1449 0.1544
Echinococcus granulosus CDC7 cell division cycle 7 0.0369 0.0533 0.0565
Echinococcus multilocularis cyclin dependent kinase 1 0.0588 0.1033 0.1029
Loa Loa (eye worm) hypothetical protein 0.0258 0.0281 0.0313
Brugia malayi phosphoinositide-dependent protein kinase I 0.0284 0.0341 0.0378
Trichomonas vaginalis CK1 family protein kinase 0.0412 0.0631 0.3025
Brugia malayi Peroxidasin 0.015 0.0035 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0171 0.0084 0.0336
Entamoeba histolytica protein kinase domain containing protein 0.0171 0.0084 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.0346 0.0481 0.2286
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0771 0.1449 0.1445
Loa Loa (eye worm) hypothetical protein 0.0785 0.1481 0.1651
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0588 0.1033 0.5875

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 11.2202 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) = 79.4328 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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