Detailed information for compound 1526176

Basic information

Technical information
  • TDR Targets ID: 1526176
  • Name: 2-[(3R,4R)-4-methyl-2-oxo-1-(phenylmethyl)pyr rolidin-3-yl]-N-(phenylmethyl)acetamide
  • MW: 336.427 | Formula: C21H24N2O2
  • H donors: 1 H acceptors: 2 LogP: 2.5 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C[C@@H]1[C@@H](C)CN(C1=O)Cc1ccccc1)NCc1ccccc1
  • InChi: 1S/C21H24N2O2/c1-16-14-23(15-18-10-6-3-7-11-18)21(25)19(16)12-20(24)22-13-17-8-4-2-5-9-17/h2-11,16,19H,12-15H2,1H3,(H,22,24)/t16-,19+/m0/s1
  • InChiKey: MXZGYHOTWXERIE-QFBILLFUSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[(3R,4R)-4-methyl-2-oxo-1-(phenylmethyl)-3-pyrrolidinyl]-N-(phenylmethyl)acetamide
  • N-(benzyl)-2-[(3R,4R)-1-(benzyl)-2-keto-4-methyl-pyrrolidin-3-yl]acetamide
  • 2-[(3R,4R)-4-methyl-2-oxo-1-(phenylmethyl)pyrrolidin-3-yl]-N-(phenylmethyl)ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) glutathione reductase 0.0046 0.011 0.0286
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Brugia malayi sulfakinin receptor protein 0.0707 0.2297 0.4196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0035 0.0024
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0035 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Onchocerca volvulus 0.0707 0.2297 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Schistosoma mansoni growth hormone secretagogue receptor 0.0707 0.2297 0.4702
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0097 0.028 0.0565
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Schistosoma mansoni hypothetical protein 0.0334 0.1064 0.2179
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0066 0.1356
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi Pre-SET motif family protein 0.0609 0.1975 0.3607
Brugia malayi Thioredoxin reductase 0.0046 0.011 0.0197
Chlamydia trachomatis endonuclease IV 0.0074 0.0205 1
Brugia malayi PXA domain containing protein 0.0037 0.0081 0.0144
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0021 0.0034
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0076 0.0147
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0037 0.0081 0.0157
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0982 0.3209 0.8504
Brugia malayi G-protein coupled receptor 0.0707 0.2297 0.4196
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Echinococcus granulosus tachykinin peptides receptor 99D 0.0707 0.2297 0.4697
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0046 0.0109 0.0098
Echinococcus granulosus orexin receptor type 2 0.0707 0.2297 0.4697
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0189 0.0378
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Onchocerca volvulus Neuropeptide F receptor homolog 0.0707 0.2297 1
Giardia lamblia PHD finger protein 15 0.0029 0.0054 0.4361
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0016 0.0013 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0066 0.0056
Loa Loa (eye worm) melatonin receptor type 1A 0.0707 0.2297 0.6086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium ulcerans oxidoreductase 0.0046 0.0109 0.0098
Echinococcus granulosus neuropeptide receptor 0.0707 0.2297 0.4697
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0011 0.0044
Echinococcus multilocularis neuropeptide receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0021 0.0049
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0205 0.0194
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0081 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0383
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0014 0.0029
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0109 0.5612
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0305 0.0294
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.011 0.4348
Mycobacterium ulcerans short chain dehydrogenase 0.3034 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Schistosoma mansoni zinc finger protein 0.0015 0.0008 0.0017
Toxoplasma gondii ABC1 family protein 0.0036 0.0076 0.0222
Toxoplasma gondii exonuclease III APE 0.0021 0.0029 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis G protein coupled receptor 139 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0081 0.0144
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0076 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus granulosus zinc finger protein 0.0019 0.0022 0.0037
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0033 0.0055
Echinococcus multilocularis microtubule associated protein 2 0.0721 0.2345 0.4796
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Entamoeba histolytica hypothetical protein 0.0046 0.0109 0.5612
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0027 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0013 0.0019
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0033 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0707 0.2297 0.6086
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0087 0.0247 0.0498
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.164
Echinococcus multilocularis g-protein coupled receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Brugia malayi TAR-binding protein 0.019 0.0586 0.1067
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0109 0.0554
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0021 0.005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0087 0.0247 0.075
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0387
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0046 0.0109 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0077 0.0331
Trypanosoma brucei unspecified product 0.0016 0.0009 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0077 0.0331
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0707 0.2297 0.4196
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0077 0.0387
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0037 0.0081 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0033 0.0022
Brugia malayi latrophilin 2 splice variant baaae 0.0204 0.0634 0.1155
Echinococcus granulosus 7tm_1 domain containing protein 0.0707 0.2297 0.4697
Trypanosoma brucei unspecified product 0.0016 0.0009 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0076 0.0065
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0707 0.2297 0.6086
Brugia malayi Bromodomain containing protein 0.0031 0.0061 0.0108
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0046 0.0109 0.0223
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1152 0.3772 1
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0046 0.0109 0.5612
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0707 0.2297 0.4697
Echinococcus multilocularis sex peptide receptor 0.0707 0.2297 0.4697
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0295 0.1523
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0305 0.0294
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0021 0.0049
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0046 0.0109 0.0195
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0189 0.097
Echinococcus granulosus hypothetical protein 0.0046 0.0109 0.0214
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Schistosoma mansoni alpha-1 adrenergic receptor 0.0707 0.2297 0.4702
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Schistosoma mansoni hypothetical protein 0.0204 0.0634 0.1298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0029 1
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0033 0.0022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0029 0.0136
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.0271 0.0546
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Brugia malayi hypothetical protein 0.0046 0.0109 0.0195
Schistosoma mansoni ap endonuclease 0.0021 0.0029 0.0059
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000030315
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0097 0.028 0.0508
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0154 0.0307
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus multilocularis cysteine protease 0.0016 0.0013 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0081 0.0157
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0037 0.0081 0.0157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0046 0.0109 0.0098
Brugia malayi MH2 domain containing protein 0.0144 0.0435 0.0792
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Mycobacterium tuberculosis Probable reductase 0.0105 0.0305 0.0294
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0046 0.0109 0.0323
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0046 0.0109 0.0098
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0013
Onchocerca volvulus 0.0046 0.0109 0.0464
Brugia malayi Latrophilin receptor protein 2 0.0094 0.0271 0.0491
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0076 0.0065
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0079 0.0341
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus multilocularis neuropeptides capa receptor 0.0707 0.2297 0.4697
Echinococcus granulosus biogenic amine 5HT receptor 0.0836 0.2726 0.5576
Brugia malayi oxidoreductase 0.0046 0.0109 0.0195
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0018 0.0392
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0707 0.2297 0.6086
Plasmodium vivax glutathione reductase, putative 0.0046 0.011 0.4348
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Schistosoma mansoni retinal dehydrogenase 0.0046 0.0109 0.0223
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0013
Brugia malayi glutathione reductase 0.0046 0.011 0.0197
Brugia malayi regulator of G-protein signaling rgs-7 0.0037 0.0081 0.0144
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0109 0.0464
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Echinococcus granulosus beta-adrenergic receptor kinase 0.0037 0.0081 0.0157
Schistosoma mansoni biogenic amine (5HT) receptor 0.1489 0.4885 1
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Leishmania major hypothetical protein, conserved 0.0026 0.0043 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0205 0.037
Loa Loa (eye worm) TAR-binding protein 0.019 0.0586 0.1547
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0021 0.0096
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0043 0.1567
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Schistosoma mansoni rab6-interacting 0.0019 0.0021 0.0044
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0046 0.0109 0.0473
Brugia malayi hypothetical protein 0.0026 0.0043 0.0074
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Schistosoma mansoni lipoxygenase 0.0053 0.0135 0.0276
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0076 0.0383
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Schistosoma mansoni cytochrome P450 0.0023 0.0035 0.0071
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0035 0.0024
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0707 0.2297 0.4697
Leishmania major 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0048 0.0037
Plasmodium vivax steroid dehydrogenase, putative 0.0046 0.0109 0.4298
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma brucei trypanothione reductase 0.0046 0.011 0.056
Onchocerca volvulus 0.0046 0.0109 0.0464
Onchocerca volvulus 0.0046 0.0109 0.0464
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0027
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0707 0.2297 0.4702
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0344 0.0333
Trichomonas vaginalis steroid dehydrogenase, putative 0.0046 0.0109 0.0473
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.0021 0.0972
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0046 0.0109 0.0098
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.008 0.0155
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Onchocerca volvulus 0.0019 0.0021 0.0083
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.011 0.0099
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0035 0.0024
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0005 0.001
Echinococcus granulosus neuropeptide FF receptor 2 0.0707 0.2297 0.4697
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0026
Loa Loa (eye worm) PXA domain-containing protein 0.0037 0.0081 0.0209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0048 0.0037
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0109 0.0554
Onchocerca volvulus 0.0016 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Onchocerca volvulus 0.0694 0.2254 0.9813
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0068 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei oxidoreductase-like protein 0.0046 0.0109 0.0554
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0247 0.0506
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0021 0.0096
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.008 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0303 0.0621
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.0271 0.0712
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.008 0.0206
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0013 0.0095
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0189 0.057
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0077 0.0148
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0011 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Toxoplasma gondii thioredoxin reductase 0.0046 0.011 0.0327
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0154 0.0307
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0029 0.0136
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0097 0.028 0.0574
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis RUN 0.0019 0.0021 0.0035
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0005
Echinococcus multilocularis beta adrenergic receptor kinase 0.0037 0.0081 0.0157
Brugia malayi beta-lactamase 0.0036 0.0076 0.0135
Echinococcus granulosus bloom syndrome protein 0.0021 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0081 0.0144
Schistosoma mansoni bromodomain containing protein 0.0063 0.0166 0.0339
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0035 0.0024
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0327
Mycobacterium ulcerans carveol-like dehydrogenase 0.0046 0.0109 0.0098
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Trichomonas vaginalis set domain proteins, putative 0.0693 0.2253 1
Onchocerca volvulus 0.0707 0.2297 1
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0011 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0054 0.202
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0035 0.0024
Plasmodium falciparum steroid dehydrogenase, putative 0.0046 0.0109 0.5064
Echinococcus multilocularis GPCR, family 2 0.0094 0.0271 0.0546
Leishmania major DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.0021 0.0052
Mycobacterium ulcerans short-chain type oxidoreductase 0.0046 0.0109 0.0098
Plasmodium falciparum phd finger protein, putative 0.0029 0.0054 0.2209
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0076 0.0065
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0013 0.0017
Loa Loa (eye worm) inositol-1 0.0037 0.0079 0.0204
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0068 0.0341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0035 0.0024
Mycobacterium leprae putative cytochrome p450 0.0023 0.0035 0.0364
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Echinococcus granulosus geminin 0.0334 0.1064 0.2172
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0035 0.0024
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.011
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0707 0.2297 0.4702
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi Dopamine receptor 0.0707 0.2297 0.4196
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0013 0.0045
Echinococcus granulosus RUN 0.0019 0.0021 0.0035
Onchocerca volvulus 0.0707 0.2297 1
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0035 0.0094
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0076 0.0065
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0048 0.0037
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0068 0.0057
Brugia malayi G-protein coupled receptor 0.0707 0.2297 0.4196
Loa Loa (eye worm) RGS-3 protein 0.0037 0.0081 0.0209
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0048 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0035 0.0024
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0153
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0707 0.2297 0.4697
Echinococcus granulosus GPCR family 2 0.0094 0.0271 0.0546
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0033 0.0058
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0081 0.0166
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0707 0.2297 0.4697
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0707 0.2297 0.4702
Schistosoma mansoni hypothetical protein 0.002 0.0026 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0156
Entamoeba histolytica hypothetical protein 0.0026 0.0044 0.2204
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0068 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0035 0.0024
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.089 0.4612
Loa Loa (eye worm) neuropeptide F receptor 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0032 0.0057
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0074 0.0205 0.0536
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0029 0.0018
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0006 0.0007
Brugia malayi Cytochrome P450 family protein 0.0033 0.0068 0.012
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0033 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0303 0.0621
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0122
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0028
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0021 0.0034
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0035 0.0364
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0046 0.0109 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0011 0.0044
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0035 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0013 0.0543
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0189 0.0387
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0046 0.0109 0.0473
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0081 0.0166
Echinococcus granulosus Regulator of G protein signaling 20 0.0037 0.0081 0.0157
Echinococcus multilocularis Regulator of G protein signaling 20 0.0037 0.0081 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Brugia malayi Bromodomain containing protein 0.0074 0.0204 0.0369
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0081 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0081 0.0157
Brugia malayi jmjC domain containing protein 0.0037 0.008 0.0142
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0027 0.0108
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0013 0.0054
Brugia malayi G protein-coupled receptor 0.0707 0.2297 0.4196
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0029 0.1381
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0435 0.1148
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Loa Loa (eye worm) hypothetical protein 0.007 0.019 0.0498
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.164
Trichomonas vaginalis esterase, putative 0.0036 0.0076 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0407 0.0825
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.011 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0021 0.0096
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0046 0.0109 0.0214
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0011 0.0038
Leishmania major dehydrogenase-like protein 0.0046 0.0109 0.0554
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0109 0.0214
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0707 0.2297 0.4702
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0109 0.5612
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0035 0.0024
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Echinococcus multilocularis cysteine protease 0.0016 0.0013 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0021 0.0043
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1021 0.3339 0.6102
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Onchocerca volvulus Alhambra homolog 0.0029 0.0054 0.0223
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.0711 0.0701
Plasmodium vivax vivapain-2 0.0016 0.0013 0.0335
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Echinococcus multilocularis fmrfamide receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0021 0.0096
Brugia malayi larval opioid receptor 0.0707 0.2297 0.4196
Schistosoma mansoni neuropeptide F-like receptor 0.0707 0.2297 0.4702
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0035 0.0024
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0021 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0076 0.0327
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0081 0.0157
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0012 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0387
Toxoplasma gondii cathepsin CPL 0.0016 0.0013 0.0027
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0014 0.0029
Brugia malayi Serotonin receptor 0.0707 0.2297 0.4196
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0035 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.0299 0.0947 0.1727
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0021 0.0034
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0044 0.0124
Echinococcus granulosus allatostatin A receptor 0.0707 0.2297 0.4697
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0046 0.0109 1
Brugia malayi AKH receptor 0.0707 0.2297 0.4196
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0014 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi Dehydrogenases, short chain protein 2 0.0046 0.0109 0.0195
Echinococcus multilocularis serotonin receptor 0.0836 0.2726 0.5576
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.011 0.056
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0054 0.0101
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Onchocerca volvulus 0.0036 0.0076 0.0321
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0109 0.0464
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Brugia malayi Dehydrogenases, short chain protein 30 0.0046 0.0109 0.0195
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0707 0.2297 0.4702
Onchocerca volvulus 0.0027 0.0048 0.02
Onchocerca volvulus 0.0054 0.0135 0.058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0044 0.0186
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0135 0.0267
Loa Loa (eye worm) beta-lactamase 0.0036 0.0076 0.0195
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0048 0.079
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0076 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0021 0.0096
Giardia lamblia Reductase, putative 0.0046 0.0109 1
Echinococcus multilocularis tar DNA binding protein 0.019 0.0586 0.1191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0048 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0109 0.5612
Schistosoma mansoni lipoxygenase 0.0019 0.0021 0.0044
Onchocerca volvulus 0.0046 0.0109 0.0464
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0054 0.0101
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0079 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Onchocerca volvulus Sepiapterin reductase homolog 0.0046 0.0109 0.0464
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0029 0.0117
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0031
Echinococcus granulosus microtubule associated protein 2 0.0721 0.2345 0.4796
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0044 0.0218
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0707 0.2297 0.4697
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0043 0.0209
Entamoeba histolytica hypothetical protein 0.0071 0.0192 1
Schistosoma mansoni alpha glucosidase 0.0036 0.0077 0.0157
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0006
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0079 0.0068
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0109 0.0098
Brugia malayi A-kinase anchor protein 10, precursor 0.0037 0.0081 0.0144
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0707 0.2297 0.4196
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0035 0.0024
Loa Loa (eye worm) hypothetical protein 0.0049 0.0122 0.0317
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0192 0.0385
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0109 0.0214
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Giardia lamblia GTOR 0.0019 0.0021 0.1017
Brugia malayi Bromodomain containing protein 0.0038 0.0084 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Brugia malayi Tachykinin-like peptides receptor 99D 0.0707 0.2297 0.4196
Onchocerca volvulus 0.0016 0.0013 0.0045
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0081 0.0157
Echinococcus granulosus steroid dehydrogenase 0.0046 0.0109 0.0214
Echinococcus granulosus Ankyrin 0.0014 0.0005 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Echinococcus multilocularis Ankyrin 0.0014 0.0005 0.0001
Mycobacterium ulcerans dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0029 0.005
Mycobacterium ulcerans hypothetical protein 0.0036 0.0076 0.0065
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0109 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0013 0.0543
Onchocerca volvulus 0.0707 0.2297 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0048 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0033 0.1592
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0033 0.008
Echinococcus multilocularis dro:myosuppressin receptor 0.0707 0.2297 0.4697
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0945 0.3085 0.6312
Onchocerca volvulus 0.0046 0.0109 0.0464
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0148 0.0756
Echinococcus granulosus expressed protein 0.0724 0.2353 0.4812
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0074 0.0142
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0013 0.0095
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0707 0.2297 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Onchocerca volvulus 0.0046 0.0109 0.0464
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) ctsf protein 0.0016 0.0013 0.0027
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0595 0.1926 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus jumonji domain containing protein 0.004 0.0091 0.0177
Plasmodium falciparum thioredoxin reductase 0.0046 0.011 0.5127
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0011 0.0044
Echinococcus multilocularis zinc finger protein 0.0019 0.0022 0.0037
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0026
Leishmania major short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0004
Plasmodium vivax vivapain-2 0.0016 0.0013 0.0335
Leishmania major cytochrome p450-like protein 0.0023 0.0035 0.0168
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0035 0.0024
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0235 0.1209
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0136
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0109 0.0214
Schistosoma mansoni myosin xvIII 0.0707 0.2297 0.4702
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0995 0.3251 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0044 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0021 0.0035
Echinococcus granulosus neuropeptide receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0217
Echinococcus multilocularis conserved hypothetical protein 0.0046 0.0109 0.0214
Brugia malayi hypothetical protein 0.0019 0.0021 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus granulosus peregrin 0.0031 0.0061 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0068 0.0174
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0025 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0241 0.0632
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0013 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0192 0.0385
Echinococcus multilocularis allatostatin A receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Brugia malayi dehydrogenases, short chain protein 2 0.0046 0.0109 0.0195
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0011 0.0259
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0037 0.0081 0.035
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni hypothetical protein 0.0071 0.0192 0.0394
Plasmodium vivax SET domain protein, putative 0.0087 0.0247 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0035 0.0024
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0195 0.039
Echinococcus granulosus tar DNA binding protein 0.019 0.0586 0.1191
Toxoplasma gondii endonuclease IV APN 0.0074 0.0205 0.0618
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0068 0.0341
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0305 0.8793
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Brugia malayi hypothetical protein 0.0071 0.0192 0.0347
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0109 0.0554
Onchocerca volvulus 0.0707 0.2297 1
Echinococcus multilocularis peregrin 0.0031 0.0061 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0035 0.0024
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0044 0.0218
Leishmania major short chain dehydrogenase-like protein 0.0046 0.0109 0.0554
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0081 0.0157
Brugia malayi G protein-coupled receptor F59B2.13 0.0707 0.2297 0.4196
Echinococcus granulosus somatostatin receptor 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0118 0.0349 0.0635
Brugia malayi Cytochrome P450 family protein 0.0085 0.0241 0.0436
Schistosoma mansoni histamine h1 receptor 0.0707 0.2297 0.4702
Schistosoma mansoni neuropeptide receptor 0.0707 0.2297 0.4702
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0189 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.0031
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium ulcerans oxidoreductase 0.0046 0.0109 0.0098
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Brugia malayi PXA domain containing protein 0.0037 0.0081 0.0144
Brugia malayi neuropeptide F receptor 0.0707 0.2297 0.4196
Loa Loa (eye worm) TYRA-2 protein 0.0707 0.2297 0.6086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi cytochrome P450 0.0023 0.0035 0.0059
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0054 0.011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus multilocularis neuropeptides capa receptor 0.0707 0.2297 0.4697
Echinococcus granulosus fmrfamide receptor 0.0707 0.2297 0.4697
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.008 0.0164
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0077 0.0331
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0035 0.0024
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0155 0.0406
Leishmania major oxidoreductase-like protein 0.0046 0.0109 0.0554
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0048 0.079
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0046 0.0109 0.0283
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0035 0.0024
Onchocerca volvulus 0.0093 0.0267 0.1155
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0609 0.1975 0.5232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0011 0.0259
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0046 0.0109 0.2681
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0013 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0046 0.0109 0.0473
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0033 0.0134
Onchocerca volvulus 0.0019 0.0021 0.0083
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0076 0.0156
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0013 0.0017
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0037 0.0081 0.0209
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0035 0.0024
Echinococcus granulosus histone lysine methyltransferase setb 0.0104 0.0303 0.0613
Echinococcus granulosus neuropeptide Y receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0033 0.0058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0076 0.0065
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Echinococcus multilocularis orexin receptor type 2 0.0707 0.2297 0.4697
Brugia malayi Retinol dehydrogenase 12 0.0046 0.0109 0.0195
Brugia malayi Serotonin receptor 0.1666 0.547 1
Brugia malayi RNA binding protein 0.019 0.0586 0.1067
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0107
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0029 0.0136
Schistosoma mansoni inositol monophosphatase 0.0037 0.0079 0.0162
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.0104 0.0303 0.0798
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0035 0.0024
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0195
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0081 0.0157
Echinococcus granulosus serotonin receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Onchocerca volvulus 0.0016 0.0013 0.0045
Schistosoma mansoni inositol monophosphatase 0.0037 0.0079 0.0162
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Loa Loa (eye worm) hypothetical protein 0.0836 0.2726 0.7224
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0109 0.0323
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0079 0.0341
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0707 0.2297 0.4702
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0033 0.0067
Mycobacterium ulcerans beta-lactamase 0.0036 0.0076 0.0065
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0707 0.2297 0.4697
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0029 0.099
Loa Loa (eye worm) hypothetical protein 0.0308 0.0978 0.2588
Brugia malayi PHD-finger family protein 0.0029 0.0054 0.0094
Schistosoma mansoni hypothetical protein 0.0707 0.2297 0.4702
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0026 0.0062
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0109 0.0214
Loa Loa (eye worm) G-protein coupled receptor 0.0707 0.2297 0.6086
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.089 0.4612
Echinococcus multilocularis serotonin receptor 0.0836 0.2726 0.5576
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0079 0.4041
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0595 0.1926 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0035 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0035 0.0168
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0097 0.028 0.1444
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0076 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Onchocerca volvulus 0.0707 0.2297 1
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0023 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0005
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0305 0.0294
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0025 0.0015
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0493 0.0897
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0077 0.0331
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0109 0.4298
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0305 0.0294
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0021 0.0096
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0021 0.0096
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.0021 0.0972
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0086 0.0242 0.0636
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0081 0.0157
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Echinococcus granulosus 7TM GPCR rhodopsin 0.0707 0.2297 0.4697
Echinococcus granulosus hypothetical protein 0.0046 0.0109 0.0214
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0223
Brugia malayi follicle stimulating hormone receptor 0.1152 0.3772 0.6895
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0037 0.0081 0.0144
Echinococcus granulosus dro:myosuppressin receptor 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0344 0.0333
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0205 1
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0046 0.0109 0.0223
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0407 0.1074
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0109 0.5612
Echinococcus granulosus hypothetical protein 0.1441 0.4728 0.968
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0048 0.2418
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0043 0.0119
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0081 0.0144
Onchocerca volvulus 0.0016 0.0013 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0707 0.2297 1
Brugia malayi Pre-SET motif family protein 0.0087 0.0247 0.0448
Onchocerca volvulus 0.0087 0.0247 0.1068
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0109 0.5064
Brugia malayi Dopamine receptor protein 2 0.0707 0.2297 0.4196
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0021 0.0097
Echinococcus multilocularis regulator of G protein signaling 0.0037 0.0081 0.0157
Onchocerca volvulus 0.0036 0.0076 0.0321
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus multilocularis neuropeptide receptor A26 0.0707 0.2297 0.4697
Mycobacterium ulcerans endonuclease IV 0.0074 0.0205 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Schistosoma mansoni ap endonuclease 0.0021 0.0029 0.0059
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0035 0.0024
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0046 0.0109 0.5064
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0046 0.0109 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0493 0.1301
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0109 0.0554
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0033 0.0157
Onchocerca volvulus 0.0016 0.0013 0.0045
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0025 0.0757
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.0271 0.0546
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Leishmania major cytochrome p450-like protein 0.0033 0.0068 0.0341
Toxoplasma gondii carbonyl reductase 1, putative 0.0046 0.0109 0.0323
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0195 0.039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0029 0.0136
Toxoplasma gondii hypothetical protein 0.0096 0.0276 0.0836
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.089 0.4612
Echinococcus multilocularis neuropeptide FF receptor 2 0.0707 0.2297 0.4697
Onchocerca volvulus 0.0046 0.0109 0.0464
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Onchocerca volvulus 0.0707 0.2297 1
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0323
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0344 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0027 0.0108
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0011 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Leishmania major cytochrome p450-like protein 0.0023 0.0035 0.0168
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0035 0.0024
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0046 0.0109 0.0195
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0035 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Schistosoma mansoni alpha-glucosidase 0.0139 0.0418 0.0856
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0023 0.009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0037 0.0081 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0036 0.0076 0.0321
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0035 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0166 0.085
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0081 0.0166
Schistosoma mansoni hypothetical protein 0.0023 0.0035 0.0071
Echinococcus multilocularis 0.0023 0.0035 0.0062
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.2681
Schistosoma mansoni DNA polymerase eta 0.0022 0.0033 0.0067
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0029 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Schistosoma mansoni microtubule-associated protein tau 0.0721 0.2345 0.48
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0707 0.2297 0.4196
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0029 0.0916
Brugia malayi jmjC domain containing protein 0.0094 0.0271 0.0491
Onchocerca volvulus 0.0046 0.0109 0.0464
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0299 0.0947 0.1727
Entamoeba histolytica cysteine protease, putative 0.0016 0.0013 0.0543
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0135 0.0267
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0076 0.0135
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0014 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0707 0.2297 0.4697
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.0271 0.0491
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Leishmania major short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0595 0.1926 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0407 0.074
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0046 0.0109 0.0098
Brugia malayi Protein kinase domain containing protein 0.0014 0.0004 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0707 0.2297 0.4697
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0017
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0407 0.0825
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0021 0.0096
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0109 0.0214
Schistosoma mansoni eyes absent homolog 0.0086 0.0242 0.0496
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0109 0.0554
Echinococcus granulosus neuropeptides capa receptor 0.0707 0.2297 0.4697
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0009 0.0037
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.011 0.0286
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0013 0.0054
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.2681
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0035 0.0024
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.0271 0.0546
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0109 0.0323
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0079 0.0341
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Leishmania major DNA polymerase eta, putative 0.0022 0.0033 0.0157
Leishmania major mitochondrial DNA polymerase beta 0.0595 0.1926 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0077 0.0331
Loa Loa (eye worm) hypothetical protein 0.1021 0.3339 0.885
Echinococcus multilocularis neuropeptide receptor 0.0707 0.2297 0.4697
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Onchocerca volvulus 0.0016 0.0013 0.0045
Mycobacterium tuberculosis Conserved protein 0.0036 0.0076 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0407 0.0825
Echinococcus multilocularis conserved hypothetical protein 0.0735 0.239 0.4888
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0076 0.2944
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0104 0.0303 0.0613
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0305 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus granulosus oxidoreductase 0.0046 0.0109 0.0214
Mycobacterium ulcerans epimerase 0.002 0.0023 0.0012
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0707 0.2297 0.4196
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0091 0.0177
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Schistosoma mansoni netrin receptor unc5 0.0014 0.0004 0.0009
Loa Loa (eye worm) cytochrome P450 0.0023 0.0035 0.0086
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.011 0.0217
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0054
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Trypanosoma brucei unspecified product 0.0022 0.0033 0.0157
Onchocerca volvulus 0.0707 0.2297 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0035 0.0024
Loa Loa (eye worm) neuropeptide F receptor 0.0707 0.2297 0.6086
Loa Loa (eye worm) hypothetical protein 0.0042 0.0098 0.0254
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0189 0.0178
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0079 0.6959
Brugia malayi dehydrogenases, short chain protein 9 0.0046 0.0109 0.0195
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0035 0.0024
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0109 0.0214
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0081 0.0157
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0046 0.0109 0.0098
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0029 0.181
Echinococcus granulosus g-protein coupled receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0068 0.0174
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0044 0.0077
Echinococcus multilocularis geminin 0.0334 0.1064 0.2172
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Onchocerca volvulus 0.0046 0.0109 0.0464
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0048 0.2418
Brugia malayi RNA recognition motif domain containing protein 0.019 0.0586 0.1067
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0192 0.0394
Onchocerca volvulus 0.0707 0.2297 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0021 0.0096
Mycobacterium ulcerans dehydrogenase 0.0046 0.0109 0.0098
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0011 0.0021
Schistosoma mansoni amine GPCR 0.0707 0.2297 0.4702
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0048 0.2418
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0076 0.0147
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0021 0.0035
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0021 0.0096
Echinococcus multilocularis retinol dehydrogenase 13 0.0046 0.0109 0.0214
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0048 0.0239
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi putative neuropeptide receptor 0.0707 0.2297 0.4196
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000030315
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0189 0.0378
Mycobacterium leprae Probable oxidoreductase 0.0046 0.0109 0.2681
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.0204 0.0634 0.1675
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Schistosoma mansoni neuropeptide f receptor 76f 0.0707 0.2297 0.4702
Echinococcus multilocularis neuropeptide Y receptor 0.0707 0.2297 0.4697
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0046 0.0109 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0707 0.2297 0.4702
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0076 0.0383
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0079 0.0231
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0109 0.0554
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Brugia malayi GnHR receptor homolog 0.0707 0.2297 0.4196
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0323
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0109 0.0554
Leishmania major hypothetical protein, conserved 0.0036 0.0076 0.0383
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Echinococcus granulosus sex peptide receptor 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0035 0.0024
Brugia malayi RE15519p 0.0707 0.2297 0.4196
Echinococcus multilocularis dna polymerase eta 0.0022 0.0033 0.0058
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0044 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0153
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0016 0.0037
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.0271 0.0546
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0081 0.0166
Echinococcus granulosus cathepsin l1 0.0016 0.0013 0.0017
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0077 0.0148
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0081 0.0166
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0033 0.0022
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0129 0.0337
Brugia malayi hypothetical protein 0.0037 0.0081 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0046 0.0109 0.0464
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Mycobacterium ulcerans hypothetical protein 0.0313 0.0995 0.0985
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0029 0.007
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0013 0.0095
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0299 0.0947 0.2505
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0044 0.0082
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0046 0.0109 0.2681
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0027 0.0045
Echinococcus granulosus peptide allatostatin:somatostatin 0.0707 0.2297 0.4697
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Schistosoma mansoni carbonyl reductase 0.0046 0.0109 0.0223
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0021 0.054
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0109 0.0214
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0109 0.0223
Loa Loa (eye worm) RecQ helicase 0.0021 0.0027 0.0065
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0055
Brugia malayi beta-lactamase family protein 0.0036 0.0076 0.0135
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0084 0.0237 0.0476
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0032 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0035 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0011 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0022 0.0011
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0013 0.0027
Echinococcus granulosus dna polymerase kappa 0.0022 0.0033 0.0058
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus neuropeptide receptor A26 0.0707 0.2297 0.4697
Echinococcus granulosus dna polymerase eta 0.0022 0.0033 0.0058
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Probable dehydrogenase 0.0046 0.0109 0.0098
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0029 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0035 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.0707 0.2297 0.4697
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0707 0.2297 0.4702
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0081 0.0157
Schistosoma mansoni loxhd1 0.0019 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0035 0.0024
Plasmodium falciparum glutathione reductase 0.0046 0.011 0.5127
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0205 0.5664
Brugia malayi Inositol-1 0.0037 0.0079 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Brugia malayi neuropeptide F receptor 0.0707 0.2297 0.4196
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis somatostatin receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) hypothetical protein 0.1021 0.3339 0.885
Schistosoma mansoni biogenic amine receptor 0.0707 0.2297 0.4702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Schistosoma mansoni adenoreceptor 0.0707 0.2297 0.4702
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0032 0.0066
Leishmania major pteridine reductase 1 0.0046 0.0109 0.0554
Onchocerca volvulus 0.0707 0.2297 1
Leishmania major cathepsin L-like protease 0.0063 0.0166 0.085
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0081 0.035
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0109 0.0554
Onchocerca volvulus 0.0046 0.0109 0.0464
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0035 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0086 0.0242 0.0636
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni amine GPCR 0.0883 0.288 0.5896
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0109 0.0098
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0033 0.0055
Schistosoma mansoni opsin-like receptor 0.0707 0.2297 0.4702
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0493 0.1001
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0087 0.0247 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1021 0.3339 0.6835
Leishmania major trypanothione reductase 0.0046 0.011 0.056
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0109 0.0223
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0033 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0109 0.0554
Echinococcus granulosus alpha 1A adrenergic receptor 0.0707 0.2297 0.4697
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0004
Brugia malayi Melatonin receptor type 1A 0.0707 0.2297 0.4196
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0013 0.0017
Brugia malayi Cytochrome P450 family protein 0.0033 0.0068 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0707 0.2297 0.4702
Echinococcus multilocularis neuropeptide Y receptor 0.0707 0.2297 0.4697
Giardia lamblia Short-chain dehydrogenase, putative 0.0046 0.0109 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0023 0.0012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.3921
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0109 0.0098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0029 0.0018
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0046 0.0109 0.2681
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0344 0.0333
Brugia malayi Dopamine receptor protein 1 0.0707 0.2297 0.4196
Echinococcus multilocularis g protein coupled receptor 0.0707 0.2297 0.4697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Onchocerca volvulus 0.0046 0.0109 0.0464
Mycobacterium ulcerans lipase LipD 0.0036 0.0076 0.0065
Schistosoma mansoni biogenic amine (5HT) receptor 0.0836 0.2726 0.558
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0013 0.0046
Echinococcus granulosus tm gpcr rhodopsin 0.0707 0.2297 0.4697
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0109 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.005
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0707 0.2297 0.4702
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0033 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0081 0.0166
Schistosoma mansoni zinc finger protein 0.0019 0.0022 0.0046
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis fmrfamide receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0079 0.0153
Trypanosoma brucei glucosidase, putative 0.0036 0.0077 0.0387
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0205 0.8234
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0707 0.2297 0.4697
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0076 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0076 0.0065
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0109 1
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0076 0.1656
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0076 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0035 0.0024
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0207 0.0423
Brugia malayi ORL1-like opioid receptor 0.0707 0.2297 0.4196
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0044
Loa Loa (eye worm) dehydrogenase 0.0046 0.0109 0.0283
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0025 0.0863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0048 0.0084
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0037 0.0081 0.0209
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Schistosoma mansoni tar DNA-binding protein 0.019 0.0586 0.1199
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.3921
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0035 0.0024
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0021 0.0043
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0271 0.0546
Leishmania major hypothetical protein, conserved 0.0046 0.0109 0.0554
Brugia malayi PHD-finger family protein 0.0025 0.004 0.0069
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0097 0.028 0.0565
Brugia malayi hypothetical protein 0.0086 0.0242 0.0439
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0032 0.0057
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1489 0.4885 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0021 0.0096
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0189 0.0178
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0021 0.0034
Brugia malayi hypothetical protein 0.0016 0.0013 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0121 0.0619
Loa Loa (eye worm) hypothetical protein 0.0836 0.2726 0.7224
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Echinococcus granulosus neuropeptide s receptor 0.0707 0.2297 0.4697
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0109 0.0473
Schistosoma mansoni hypothetical protein 0.0334 0.1064 0.2179
Trypanosoma brucei ISWI complex protein 0.0015 0.0008 0.0031
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0021 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0029 0.0117
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0081 0.0157
Giardia lamblia DINP protein human, muc B family 0.0022 0.0033 0.2217
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0707 0.2297 0.4697
Loa Loa (eye worm) oxidoreductase 0.0046 0.0109 0.0283
Schistosoma mansoni polycystin 1-related 0.0019 0.0021 0.0044
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0707 0.2297 0.4702
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0077 0.0224
Loa Loa (eye worm) hypothetical protein 0.004 0.0092 0.0237
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0076 0.0327
Echinococcus granulosus WW domain containing oxidoreductase 0.0046 0.0109 0.0214
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0435 0.1148
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0021 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0035 0.0024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0029 0.181
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Brugia malayi putative neuropeptide receptor NPR1 0.0707 0.2297 0.4196
Schistosoma mansoni alpha-glucosidase 0.0139 0.0418 0.0856
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0407 0.0825
Entamoeba histolytica hypothetical protein 0.0037 0.0081 0.4149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0013 0.0046
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0004 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0707 0.2297 0.4702
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0283
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0046 0.0109 0.0214
Brugia malayi hypothetical protein 0.0046 0.0109 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0166 0.085
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0046 0.0109 0.0554
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0023 0.0012
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0054 0.0136
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0076 0.0065
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0081 0.0166
Echinococcus granulosus g protein coupled receptor 0.0707 0.2297 0.4697
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0109 0.0214
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0097 0.028 0.027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0021 0.0034
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0033 0.0058
Mycobacterium ulcerans hypothetical protein 0.0027 0.0048 0.0037
Loa Loa (eye worm) hypothetical protein 0.0299 0.0947 0.2505
Loa Loa (eye worm) hypothetical protein 0.0707 0.2297 0.6086
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0046 0.0109 0.0554
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0046 0.0109 0.0214
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0109 0.5612
Echinococcus granulosus G protein coupled receptor 139 0.0707 0.2297 0.4697
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0077 0.0197
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0035 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Mycobacterium ulcerans hypothetical protein 0.002 0.0023 0.0012
Brugia malayi hypothetical protein 0.0707 0.2297 0.4196
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0021 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0035 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.0209
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0046 0.0109 0.0323
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0061
Echinococcus multilocularis expressed protein 0.0724 0.2353 0.4812
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0033 0.0157
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.0209
Brugia malayi Cathepsin L-like precursor 0.0016 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.005
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0166 0.085
Echinococcus granulosus rhodopsin orphan GPCR 0.0707 0.2297 0.4697
Schistosoma mansoni hypothetical protein 0.0094 0.0271 0.0555
Onchocerca volvulus 0.0707 0.2297 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.0712
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0046 0.0109 0.0214
Brugia malayi Cytochrome P450 family protein 0.0023 0.0035 0.0059
Brugia malayi hypothetical protein 0.0019 0.0021 0.0035
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0046 0.0109 0.0214
Echinococcus multilocularis oxidoreductase 0.0046 0.0109 0.0214
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0271 0.0546
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0109 0.5612
Echinococcus granulosus biogenic amine 5HT receptor 0.1489 0.4885 1
Brugia malayi Doublecortin family protein 0.0019 0.0021 0.0035
Loa Loa (eye worm) fibroinase 0.0016 0.0013 0.0027
Schistosoma mansoni rab6-interacting 0.0019 0.0021 0.0044
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0109 0.0214
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0109 0.0554
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0407 0.0833
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0025 0.0757
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0035 0.0024
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0235 0.1209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0209
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0035 0.0168
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0077 0.0136
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0044
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0046 0.0109 0.0214
Mycobacterium leprae Probable lipase LipE 0.0036 0.0076 0.1656
Loa Loa (eye worm) cysteine protease 0.0016 0.0013 0.0027
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0021 0.0689
Giardia lamblia Hypothetical protein 0.0046 0.0109 1
Loa Loa (eye worm) RNA binding protein 0.019 0.0586 0.1547
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0035 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0079 0.0399
Loa Loa (eye worm) dehydrogenase 0.0046 0.0109 0.0283
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.0995 0.0985
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0109 0.0098
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.019 0.0586 0.1547
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0081 0.0157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0109 0.0195

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1312 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.2589 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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