Detailed information for compound 1086844

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 549.703 | Formula: C28H47N5O6
  • H donors: 5 H acceptors: 6 LogP: 3.56 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H]2NC(=O)[C@H](NC1=O)CCCCCCCCCCC2
  • InChi: 1S/C28H47N5O6/c34-24(32-39)18-12-8-11-15-21-25(35)29-20-14-9-6-4-2-1-3-5-7-10-16-22(31-26(20)36)28(38)33-19-13-17-23(33)27(37)30-21/h20-23,39H,1-19H2,(H,29,35)(H,30,37)(H,31,36)(H,32,34)/t20-,21+,22+,23-/m1/s1
  • InChiKey: TVNZWPOEHUTSFV-WZYRSQIMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histone deacetylase 4 Starlite/ChEMBL References
Homo sapiens histone deacetylase 1 Starlite/ChEMBL References
Homo sapiens histone deacetylase 6 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Entamoeba histolytica histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase hda2 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium berghei histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC3 Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase 7A Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Giardia lamblia Histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K06067 histone deacetylase 1/2, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K01463 Hdac3 [EC:3.5.1.-], putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum IPR000286,Histone deacetylase superfamily;IPR013838,Beta tubulin, autoregulation binding site,domain-containing Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi histone deacetylase 1 (HD1) Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium vivax histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi histone deacetylase 3 (HD3) Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma congolense histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei gambiense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum histone deacetylase HDA2/Rpd3p Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 3 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC2 Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC1 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase 2 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium vivax histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum histone deactylase of possible bacterial origin with ankyrin repeats at the N-terminus Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum RPD3/HD1 histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium yoelii Histone deacetylase family, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium falciparum histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium knowlesi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase 1,histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.009 0.0237
Echinococcus multilocularis acetylcholinesterase 0.3769 0.733 0.733
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0397 0.0731 1
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0155 0.0257 0.0281
Plasmodium vivax protein kinase Crk2 0.0048 0.0048 0.0289
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0044 0.0039 0.0239
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0028 0.0038
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0155 0.0212
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.004 0.0031 0.0154
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.008 0.011 0.015
Trypanosoma brucei unspecified product 0.0141 0.023 0.1255
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.0037 0.004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.012 0.0188 0.0188
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Echinococcus granulosus muscleblind protein 0.08 0.152 0.1661
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Brugia malayi Cell division protein ftsZ 0.0156 0.0259 0.0354
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.003 0.0158
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0046 0.0043 0.022
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0024 0.0001 0.0001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Toxoplasma gondii exonuclease III APE 0.0119 0.0188 0.1155
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0081 0.0111 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0081 0.0111 0.0152
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.012 0.0188 0.0206
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0048 0.0256
Loa Loa (eye worm) intermediate filament protein 0.0174 0.0295 0.0402
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0036 0.0025 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0081 0.0111 0.0152
Echinococcus multilocularis 0.0046 0.0043 0.0043
Trypanosoma cruzi ISWI complex protein 0.0038 0.0028 0.015
Loa Loa (eye worm) CYP4Cod1 0.0103 0.0155 0.0212
Brugia malayi ecdysone receptor 0.0038 0.0028 0.0038
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0044 0.0039 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni glutamate receptor NMDA 0.0155 0.0257 0.0281
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.004 0.0031 0.0154
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0081 0.0214
Toxoplasma gondii NAC domain-containing protein 0.0039 0.003 0.0178
Echinococcus granulosus neuropeptide s receptor 0.0978 0.1868 0.2041
Onchocerca volvulus Histone deacetylase 10 homolog 0.0242 0.0427 0.3561
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni flap endonuclease-1 0.0025 0.0003 0.0003
Echinococcus multilocularis glutamate receptor 2 0.0234 0.0412 0.0412
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0003 0.0004
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0018 0.0024
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0081 0.0111 0.0111
Echinococcus multilocularis neutral alpha glucosidase AB 0.008 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Schistosoma mansoni DNA helicase recq1 0.0042 0.0037 0.004
Echinococcus granulosus ras gtpase 0.0142 0.0232 0.0253
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Loa Loa (eye worm) CXXC zinc finger family protein 0.0363 0.0664 0.0906
Echinococcus granulosus sodium channel protein 0.0036 0.0025 0.0027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0112 0.0172 0.0938
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0436 0.0807 0.6723
Schistosoma mansoni acetyl-CoA synthetase 0.0044 0.0039 0.0043
Loa Loa (eye worm) ThiF family protein 0.0034 0.002 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.004 0.0031 0.0081
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.009 0.0487
Trypanosoma brucei histone deacetylase 1 0.0297 0.0535 0.293
Treponema pallidum fructose-bisphosphate aldolase 0.1933 0.3737 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0148 0.0243 0.0648
Schistosoma mansoni survival motor neuron protein 0.0407 0.075 0.0819
Onchocerca volvulus 0.0363 0.0664 0.5532
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.005
Schistosoma mansoni bromodomain containing protein 0.0026 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0022 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0978 0.1868 0.1868
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Chlamydia trachomatis DNA gyrase subunit B 0.0299 0.0539 0.7202
Echinococcus granulosus heat shock protein 0.0065 0.0081 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni rab6-interacting 0.0066 0.0083 0.0091
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0046 0.0043 0.0125
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0008 0.0047
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0637 0.12 0.12
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0028 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Toxoplasma gondii histone deacetylase HDAC1 0.0344 0.0627 0.3875
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0159 0.0265 0.1455
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0081 0.0111 0.0928
Plasmodium vivax histone deacetylase 2, putative 0.0344 0.0627 0.3875
Loa Loa (eye worm) inositol-1 0.0159 0.0265 0.0362
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Schistosoma mansoni bromodomain containing protein 0.0094 0.0137 0.0149
Leishmania major DNA topoisomerase IB, large subunit 0.085 0.1617 0.8867
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.004 0.0031 0.009
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0142 0.0232 0.1274
Onchocerca volvulus 0.0637 0.12 1
Echinococcus granulosus dna polymerase kappa 0.0148 0.0243 0.0266
Onchocerca volvulus 0.0264 0.047 0.3917
Echinococcus multilocularis histone deacetylase 6 0.0344 0.0627 0.0627
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0142 0.0232 0.0687
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0116 0.018 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0081 0.0111 0.0122
Brugia malayi Glutamate receptor 2 precursor 0.0155 0.0257 0.035
Trypanosoma brucei polo-like protein kinase 0.0103 0.0155 0.0848
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0273 0.0488 0.1447
Schistosoma mansoni BC026374 protein (S09 family) 0.0637 0.12 0.1311
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.004 0.0031 0.0154
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0955 0.1823 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0159 0.0265 0.1635
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0003 0.0007
Echinococcus multilocularis histone deacetylase 7 0.0344 0.0627 0.0627
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0046 0.0043 0.022
Mycobacterium ulcerans putative regultory protein 0.004 0.0031 0.0154
Schistosoma mansoni nocturnin 0.0024 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0046 0.0043 0.0125
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.0045 0.0045
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0081 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.004 0.0031 0.0081
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Schistosoma mansoni myst-related protein 0.0045 0.0042 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0071 0.0434
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0149 0.0246 0.1349
Entamoeba histolytica DNA topoisomerase III, putative 0.0034 0.0021 0.0053
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Brugia malayi nuclear receptor RXR 0.0038 0.0028 0.0038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0028 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0273 0.0488 0.0534
Echinococcus multilocularis DNA topoisomerase 1 0.085 0.1617 0.1617
Schistosoma mansoni endoplasmin 0.0065 0.0081 0.0088
Brugia malayi bHLH-PAS transcription factor 0.0081 0.0112 0.0152
Onchocerca volvulus 0.0209 0.0362 0.3015
Toxoplasma gondii hypothetical protein 0.0154 0.0255 0.1574
Plasmodium falciparum DNA topoisomerase 3, putative 0.0034 0.0021 0.0123
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0008 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0046 0.0043 0.0125
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0276 0.0495 0.0541
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0116 0.018 0.048
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0024 0.0001 0.0001
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0071 0.0093 0.0102
Toxoplasma gondii thioredoxin reductase 0.0046 0.0044 0.0266
Onchocerca volvulus 0.0024 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0061 0.0073 0.0099
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0028 0.0031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0028 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0377 0.0692 1
Trypanosoma brucei DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Brugia malayi heat shock protein 90 0.0065 0.0081 0.011
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0452 0.0838 0.4596
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0112 0.0612
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0642 0.121 0.1322
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0044 0.0039 0.02
Echinococcus multilocularis neuropeptide s receptor 0.0978 0.1868 0.1868
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0273 0.0488 0.0666
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0022 0.0029
Trypanosoma brucei chrX additional, unordered contigs 0.0037 0.0026 0.0141
Trypanosoma brucei histone deacetylase 4 0.0344 0.0627 0.3436
Onchocerca volvulus 0.0035 0.0022 0.0179
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0039 0.0103
Brugia malayi glutaminase DH11.1 0.0291 0.0524 0.0715
Toxoplasma gondii DNA topoisomerase 2, putative 0.0642 0.121 0.7482
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Loa Loa (eye worm) DNA topoisomerase III 0.0034 0.0021 0.0028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1933 0.3737 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0071 0.0385
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Plasmodium falciparum endoplasmin, putative 0.0053 0.0057 0.0346
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.0317 0.0346
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0449 0.0612
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.006 0.0066
Brugia malayi ecdysteroid receptor 0.0081 0.0111 0.0152
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Brugia malayi hypothetical protein 0.0305 0.0551 0.0752
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.0093 0.0127
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0044 0.0039 0.02
Toxoplasma gondii propionate-CoA ligase 0.0044 0.0039 0.0239
Brugia malayi PAS domain containing protein 0.0109 0.0167 0.0228
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0079 0.0109 0.0909
Schistosoma mansoni tyrosine kinase 0.0079 0.0109 0.0119
Loa Loa (eye worm) DNA topoisomerase I 0.085 0.1617 0.2206
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0396 0.0729 0.3994
Schistosoma mansoni patched 1 0.0043 0.0038 0.0042
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Trypanosoma cruzi heat shock protein 90, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Schistosoma mansoni tsg101-related 0.0183 0.0312 0.0341
Brugia malayi DNA topoisomerase III beta-1 0.0034 0.0021 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0048 0.0052
Loa Loa (eye worm) hypothetical protein 0.022 0.0384 0.0524
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0008 0.0008
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0111 0.0172 0.0172
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0028 0.0038
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.004 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni hypothetical protein 0.0148 0.0244 0.0266
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0046 0.0043 0.022
Mycobacterium tuberculosis Probable hydrolase 0.0273 0.0488 0.1447
Loa Loa (eye worm) hypothetical protein 0.08 0.152 0.2074
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.003 0.0158
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0035 0.0035
Echinococcus granulosus metabotropic glutamate receptor 5 0.0079 0.0109 0.0119
Trichomonas vaginalis inositol monophosphatase, putative 0.0159 0.0265 0.0707
Schistosoma mansoni synaptojanin 0.0024 0.0001 0.0001
Schistosoma mansoni cell polarity protein 0.0142 0.0232 0.0253
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0149 0.0246 0.0727
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0079 0.0109 0.029
Schistosoma mansoni transcription factor btf3 0.0039 0.003 0.0032
Giardia lamblia Histone deacetylase 0.0297 0.0535 0.1429
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0159 0.0471
Brugia malayi Protein kinase domain containing protein 0.0048 0.0048 0.0065
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0034 0.0021 0.0251
Leishmania major DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0046 0.0043 0.022
Treponema pallidum exodeoxyribonuclease (exoA) 0.0119 0.0188 0.05
Schistosoma mansoni neutral sphingomyelinase 0.0024 0.0001 0.0001
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0079 0.0109 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.011 0.06
Loa Loa (eye worm) carboxylesterase 0.3769 0.733 1
Trypanosoma cruzi DNA topoisomerase II, putative 0.0608 0.1143 0.6267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Loa Loa (eye worm) beta-lactamase 0.0273 0.0488 0.0666
Echinococcus granulosus flap endonuclease 1 0.0028 0.0008 0.0009
Plasmodium vivax vivapain-2 0.0035 0.0022 0.0128
Mycobacterium tuberculosis Probable lipase LipD 0.0273 0.0488 0.1447
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0155 0.0257 0.0257
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0115 0.0179 0.0195
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0119 0.0188 0.1024
Echinococcus multilocularis nmda type glutamate receptor 0.1954 0.3779 0.3779
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0182 0.0539
Loa Loa (eye worm) GTP-binding protein 0.0142 0.0232 0.0316
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0014 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0081 0.0111 0.0152
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0092 0.0135 0.0147
Toxoplasma gondii heat shock protein 90, putative 0.0065 0.0081 0.0496
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0055
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0552 0.1034 0.1034
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0046 0.0043 0.022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0082 0.0115 0.0304
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0141
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0018 0.0018
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Loa Loa (eye worm) RNA binding protein 0.0135 0.0217 0.0296
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0024 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0083 0.0116 0.0629
Loa Loa (eye worm) hypothetical protein 0.0265 0.0472 0.0644
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0116 0.018 0.0246
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.004 0.0031 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Onchocerca volvulus 0.0149 0.0246 0.205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Trichomonas vaginalis endoplasmin, putative 0.0053 0.0057 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0081 0.0111 0.0152
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Brugia malayi hypothetical protein 0.0081 0.0112 0.0153
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0042 0.0037 0.0221
Schistosoma mansoni hypothetical protein 0.0407 0.075 0.0819
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0018 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.0488 0.2675
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Entamoeba histolytica recQ family helicase, putative 0.0042 0.0037 0.0096
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0034 0.002 0.0121
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0317 0.0573 0.1699
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0044 0.0039 0.0115
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0082 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Schistosoma mansoni lamin 0.0174 0.0295 0.0322
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0086 0.0094
Schistosoma mansoni glutamate receptor NMDA 0.1637 0.3157 0.345
Echinococcus multilocularis dnaJ subfamily C 6 0.007 0.0092 0.0092
Schistosoma mansoni loxhd1 0.0066 0.0083 0.0091
Brugia malayi Cytochrome P450 family protein 0.0103 0.0155 0.0212
Schistosoma mansoni hypothetical protein 0.007 0.0092 0.01
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Loa Loa (eye worm) cysteine protease 0.0035 0.0022 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0086 0.0466
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0155 0.0848
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0079 0.0109 0.029
Loa Loa (eye worm) hypothetical protein 0.0097 0.0143 0.0195
Loa Loa (eye worm) hypothetical protein 0.0044 0.0039 0.0054
Echinococcus multilocularis heat shock protein 90 0.0025 0.0003 0.0003
Giardia lamblia Kinase, PLK 0.0103 0.0155 0.0414
Brugia malayi hypothetical protein 0.0079 0.0109 0.0149
Echinococcus granulosus histone deacetylase 0.0344 0.0627 0.0685
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) hypothetical protein 0.0084 0.0118 0.0161
Echinococcus granulosus histone deacetylase 6 0.0344 0.0627 0.0685
Brugia malayi hypothetical protein 0.0132 0.0213 0.029
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0048 0.0052
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0026 0.0141
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0155 0.0212
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0164 0.0274 0.1499
Onchocerca volvulus 0.0044 0.0039 0.0329
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0115 0.0179 0.0179
Plasmodium vivax DNA gyrase subunit A, putative 0.0137 0.0221 0.1363
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Brugia malayi hypothetical protein 0.0043 0.0037 0.005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0116 0.018 0.048
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0081 0.0111 0.0152
Loa Loa (eye worm) carboxylesterase 0.0637 0.12 0.1637
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0079 0.0109 0.0149
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0182 0.0995
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0119 0.0188 0.0205
Echinococcus granulosus inositol monophosphatase 1 0.0159 0.0265 0.029
Mycobacterium leprae Conserved hypothetical protein 0.0046 0.0043 0.022
Plasmodium vivax ubiquitin activating enzyme, putative 0.0052 0.0055 0.0336
Schistosoma mansoni steroid hormone receptor ad4bp 0.0081 0.0111 0.0122
Trypanosoma brucei trypanothione reductase 0.0046 0.0044 0.0236
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0028 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Brugia malayi Endoplasmin precursor 0.0065 0.0081 0.011
Loa Loa (eye worm) ICD-1 protein 0.0039 0.003 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Echinococcus granulosus microtubule associated protein 2 0.455 0.8859 0.968
Schistosoma mansoni heat shock protein 0.0065 0.0081 0.0088
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0028 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0044 0.0039 0.02
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Chlamydia trachomatis DNA gyrase subunit A 0.0137 0.0221 0.2555
Leishmania major mitochondrial DNA polymerase beta 0.0955 0.1823 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Schistosoma mansoni thyroid hormone receptor 0.0081 0.0111 0.0122
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Mycobacterium ulcerans two component regulator - sensor kinase 0.004 0.0031 0.0154
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0397 0.0731 0.1954
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.043 0.0795 0.1085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0081 0.0111 0.0152
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0074 0.0099 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Brugia malayi hypothetical protein 0.0637 0.12 0.1637
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.0009 0.001
Echinococcus granulosus receptor type guanylyl cyclase 0.0079 0.0109 0.0119
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Schistosoma mansoni DNA polymerase IV / kappa 0.0037 0.0026 0.0029
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0155 0.0257 0.0257
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0037 0.005
Brugia malayi Intermediate filament tail domain containing protein 0.0174 0.0295 0.0402
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0155 0.0848
Echinococcus multilocularis protein dispatched 1 0.0049 0.005 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.052 0.0972 0.1326
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0066 0.0083 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Trichomonas vaginalis DNA polymerase eta, putative 0.0148 0.0243 0.0648
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0151 0.0165
Giardia lamblia Telomerase catalytic subunit 0.0092 0.0134 0.0356
Leishmania major DNA topoisomerase ii 0.0608 0.1143 0.6267
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Plasmodium vivax histone deacetylase, putative 0.0242 0.0427 0.2639
Plasmodium vivax endoplasmin, putative 0.0065 0.0081 0.0496
Trypanosoma brucei Heat shock protein 83, putative 0.0065 0.0081 0.044
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0048 0.0125
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0018 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0046 0.0043 0.0125
Echinococcus granulosus histone deacetylase 1 0.0297 0.0535 0.0584
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0131 0.0143
Schistosoma mansoni histone deacetylase 0.0297 0.0535 0.0584
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0081 0.0111 0.0152
Echinococcus granulosus cpg binding protein 0.0386 0.0709 0.0774
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Entamoeba histolytica hypothetical protein 0.0334 0.0607 0.1624
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0022 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0048 0.0289
Schistosoma mansoni hypothetical protein 0.1605 0.3095 0.3382
Echinococcus granulosus neutral alpha glucosidase AB 0.008 0.011 0.012
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.004 0.0031 0.0034
Leishmania major histone deacetylase, putative 0.0344 0.0627 0.3436
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.0522 0.057
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Echinococcus multilocularis dna polymerase kappa 0.0148 0.0243 0.0243
Echinococcus multilocularis histone deacetylase 0.0344 0.0627 0.0627
Onchocerca volvulus 0.0052 0.0056 0.0464
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Schistosoma mansoni protein kinase 0.0079 0.0109 0.0119
Echinococcus granulosus tumor susceptibility gene 101 protein 0.022 0.0384 0.0419
Schistosoma mansoni hypothetical protein 0.0248 0.044 0.0481
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0148 0.0244 0.0244
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0022 0.0022
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0001 0.0001
Echinococcus granulosus mixed lineage leukemia protein mll 0.0092 0.0135 0.0147
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0081 0.0214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus multilocularis ras gtpase 0.0142 0.0232 0.0232
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.004 0.0031 0.0154
Brugia malayi hypothetical protein 0.0066 0.0083 0.0114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0083 0.0083
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0046 0.0043 0.022
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Entamoeba histolytica hypothetical protein 0.0092 0.0134 0.0356
Giardia lamblia DNA topoisomerase III 0.0034 0.0021 0.0053
Trichomonas vaginalis rotamase, putative 0.0066 0.0083 0.0219
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0044 0.0039 0.0043
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0149 0.0246 0.1349
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0086 0.0094
Brugia malayi hypothetical protein 0.0038 0.0028 0.0038
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0046 0.0043 0.022
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0182 0.0539
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0046 0.0043 0.0125
Brugia malayi nuclear receptor NHR-67 0.0038 0.0028 0.0038
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0137 0.0221 0.0654
Echinococcus granulosus traf and tnf receptor associated protein 0.0024 0.0001 0.0001
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0151 0.0206
Mycobacterium leprae cell division protein FtsZ 0.0326 0.0591 0.3267
Schistosoma mansoni nuclear receptor 0.0038 0.0028 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0096 0.0141 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Schistosoma mansoni glutamate receptor AMPA 0.0155 0.0257 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.01 0.011
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0112 0.069
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.009
Loa Loa (eye worm) hypothetical protein 0.0394 0.0724 0.0988
Trypanosoma brucei ISWI complex protein 0.0038 0.0028 0.015
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Schistosoma mansoni retinoic acid receptor RXR 0.0081 0.0111 0.0122
Toxoplasma gondii histone deacetylase HDAC4 0.0242 0.0427 0.2639
Schistosoma mansoni coup transcription factor 0.0081 0.0111 0.0122
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0073 0.0079
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0155 0.0848
Trypanosoma brucei DNA polymerase kappa, putative 0.0127 0.0202 0.1103
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0012 0.0061
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0034 0.0021 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0361 0.0659 0.09
Echinococcus granulosus cytochrome P450 2K1 0.0046 0.0043 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0273 0.0488 0.3017
Trypanosoma cruzi cytochrome P450, putative 0.0103 0.0155 0.0849
Brugia malayi Flap endonuclease-1 0.0028 0.0008 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Entamoeba histolytica histone deacetylase, putative 0.0297 0.0535 0.1429
Trichomonas vaginalis glutaminase, putative 0.0291 0.0524 0.14
Echinococcus multilocularis neutral sphingomyelinase 0.0024 0.0001 0.0001
Echinococcus granulosus histone deacetylase 3 0.0297 0.0535 0.0584
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0149 0.0246 0.0727
Loa Loa (eye worm) hypothetical protein 0.0053 0.0057 0.0078
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Brugia malayi PHD-finger family protein 0.0049 0.005 0.0069
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.0409 0.0559
Echinococcus multilocularis deoxyribonuclease 1 2 0.0024 0.0001 0.0001
Echinococcus granulosus histone deacetylase 8 0.0242 0.0427 0.0467
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0334 0.0607 0.1624
Echinococcus multilocularis transfer RNA-Lys 0.0081 0.0112 0.0112
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Echinococcus granulosus lamin dm0 0.0174 0.0295 0.0322
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0038 0.0038
Toxoplasma gondii histone deacetylase HDAC5 0.0242 0.0427 0.2639
Leishmania major pantothenate kinase subunit, putative 0.003 0.0013 0.0065
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0086 0.0526
Entamoeba histolytica DNA topoisomerase III, putative 0.0034 0.0021 0.0053
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0159 0.0471
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0048 0.0048
Echinococcus granulosus dual specificity 0.0098 0.0145 0.0158
Loa Loa (eye worm) hypothetical protein 0.0074 0.0099 0.0135
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0155 0.0414
Brugia malayi Latrophilin receptor protein 2 0.0115 0.0179 0.0244
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0071 0.0385
Loa Loa (eye worm) histone deacetylase 0.0344 0.0627 0.0855
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Trypanosoma cruzi cruzipain precursor, putative 0.0132 0.0212 0.116
Trypanosoma brucei hypothetical protein, conserved 0.0273 0.0488 0.2675
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0116 0.018 0.048
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.004 0.0031 0.0081
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Echinococcus granulosus neuropeptide receptor A26 0.0978 0.1868 0.2041
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Leishmania major cytochrome p450-like protein 0.0046 0.0043 0.0231
Brugia malayi DNA topoisomerase III 0.0034 0.0021 0.0028
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0155 0.0257 0.0257
Schistosoma mansoni endoplasmin 0.0065 0.0081 0.0088
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0116 0.018 0.0983
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Echinococcus granulosus tar DNA binding protein 0.0135 0.0217 0.0237
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0039 0.0103
Trypanosoma cruzi pantothenate kinase subunit, putative 0.003 0.0013 0.0065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0119 0.0188 0.1024
Schistosoma mansoni pyruvate dehydrogenase 0.004 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0041 0.0034 0.0207
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0064 0.0079 0.0483
Onchocerca volvulus 0.0035 0.0022 0.0179
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Echinococcus granulosus tumor protein p63 0.0661 0.1248 0.1364
Brugia malayi Bromodomain containing protein 0.0107 0.0163 0.0222
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0119 0.0188 0.0188
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0407 0.075 0.1023
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0018 0.0105
Brugia malayi hypothetical protein 0.0043 0.0037 0.005
Schistosoma mansoni glutamate receptor AMPA 0.0155 0.0257 0.0281
Echinococcus multilocularis endoplasmin 0.0025 0.0003 0.0003
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0079 0.0109 0.0149
Schistosoma mansoni polycystin 1-related 0.0066 0.0083 0.0091
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0044 0.0039 0.0039
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0276 0.0495 0.0495
Echinococcus multilocularis lysosomal alpha glucosidase 0.0361 0.0659 0.0659
Mycobacterium ulcerans esterase/lipase LipP 0.0273 0.0488 0.2697
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0086 0.0086
Echinococcus granulosus acetylcholinesterase 0.3769 0.733 0.8009
Brugia malayi N-terminal motif family protein 0.0394 0.0724 0.0988
Leishmania major histone deacetylase, putative 0.0297 0.0535 0.293
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0003 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0022 0.0113
Toxoplasma gondii histone lysine methyltransferase SET1 0.0692 0.1309 0.8096
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0081 0.0111 0.0122
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0012 0.003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0046 0.0043 0.0125
Mycobacterium leprae putative cytochrome p450 0.0046 0.0043 0.022
Trypanosoma cruzi DNA polymerase eta, putative 0.0147 0.0241 0.1317
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Mycobacterium leprae Possible regulatory protein 0.0028 0.0009 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0028 0.0073
Schistosoma mansoni ap endonuclease 0.0119 0.0188 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Brugia malayi TAR-binding protein 0.0135 0.0217 0.0296
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0005
Onchocerca volvulus 0.0044 0.0039 0.0329
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Loa Loa (eye worm) Ulp1 protease 0.0071 0.0093 0.0127
Schistosoma mansoni gliotactin 0.0637 0.12 0.1311
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0081 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0297 0.0535 0.073
Brugia malayi DNA topoisomerase I 0.085 0.1617 0.2206
Plasmodium falciparum heat shock protein 90 0.0065 0.0081 0.0496
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Plasmodium vivax DNA repair protein REV1, putative 0.0037 0.0026 0.0159
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Schistosoma mansoni alpha-glucosidase 0.031 0.0561 0.0613
Loa Loa (eye worm) hypoxia-induced factor 1 0.0338 0.0615 0.0839
Loa Loa (eye worm) hypothetical protein 0.0066 0.0083 0.0114
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Trichomonas vaginalis penicillin-binding protein, putative 0.0273 0.0488 0.1305
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.008 0.011 0.0677
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0064 0.008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0257 0.0457 0.0623
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0028 0.0031
Echinococcus multilocularis transcription factor btf3 0.0039 0.003 0.003
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0022 0.0055
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0044 0.0039 0.0039
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0076
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Echinococcus granulosus DNA topoisomerase 1 0.085 0.1617 0.1767
Loa Loa (eye worm) RecQ helicase 0.0042 0.0037 0.005
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0326 0.0591 0.8539
Echinococcus multilocularis heat shock protein 90 0.0065 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.0045 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Loa Loa (eye worm) hypothetical protein 0.0147 0.0241 0.0329
Schistosoma mansoni zinc finger protein 0.0038 0.0028 0.0031
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.004 0.0031 0.0166
Schistosoma mansoni aryl hydrocarbon receptor 0.0109 0.0167 0.0183
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0086 0.0094
Echinococcus multilocularis expressed conserved protein 0.0095 0.0139 0.0139
Echinococcus granulosus para nitrobenzyl esterase 0.0637 0.12 0.1311
Brugia malayi Protein kinase domain containing protein 0.0098 0.0145 0.0198
Trichomonas vaginalis rotamase, putative 0.0064 0.008 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Leishmania major telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Brugia malayi hypoxia-induced factor 1 0.0338 0.0615 0.0839
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0039 0.0054
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0044 0.0039 0.02
Toxoplasma gondii ThiF family protein 0.0034 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0202 0.035 0.0477
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0155 0.017
Entamoeba histolytica cysteine protease, putative 0.0035 0.0022 0.0055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0361 0.0659 0.09
Brugia malayi nuclear hormone receptor 0.0038 0.0028 0.0038
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Echinococcus granulosus survival motor neuron protein 1 0.1994 0.3857 0.4215
Brugia malayi hypothetical protein 0.0066 0.0083 0.0114
Loa Loa (eye worm) hypothetical protein 0.043 0.0795 0.1085
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0082 0.0115 0.0304
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0217 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0115 0.0179 0.0244
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0024 0.0001 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0081 0.0111 0.0152
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0057 0.015
Mycobacterium ulcerans cell division protein FtsZ 0.0326 0.0591 0.3267
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0377 0.0692 0.1849
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0083 0.0091
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.029 0.0522 0.0712
Onchocerca volvulus 0.0038 0.0028 0.0234
Echinococcus multilocularis dna polymerase eta 0.0147 0.0241 0.0241
Chlamydia trachomatis glutamine binding protein 0.0397 0.0731 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0046 0.0043 0.022
Trichomonas vaginalis sensor histidine kinase, putative 0.004 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.0265 0.0472 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Echinococcus multilocularis cpg binding protein 0.0386 0.0709 0.0709
Trypanosoma brucei cytochrome P450, putative 0.0103 0.0155 0.0849
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0028 0.0038
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0112 0.0172 0.1839
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0055 0.0145
Loa Loa (eye worm) hypothetical protein 0.0081 0.0113 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0038 0.01
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0079 0.0108
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Echinococcus granulosus nmda type glutamate receptor 0.1482 0.2854 0.3118
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0051 0.0054 0.0142
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0637 0.12 0.3559
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0397 0.0731 0.1954
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Echinococcus multilocularis lamin 0.0174 0.0295 0.0295
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0241
Echinococcus granulosus dna polymerase eta 0.0147 0.0241 0.0263
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0022 0.0023
Loa Loa (eye worm) cytochrome P450 0.0046 0.0043 0.0059
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Mycobacterium tuberculosis Probable sensor protein KdpD 0.004 0.0031 0.009
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Echinococcus multilocularis microtubule associated protein 2 0.455 0.8859 0.8859
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Mycobacterium tuberculosis Probable esterase LipL 0.0273 0.0488 0.1447
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0046 0.0043 0.022
Mycobacterium leprae Probable two component sensor kinase MprB 0.004 0.0031 0.0154
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0642 0.121 0.121
Schistosoma mansoni SET domain protein 0.0043 0.0038 0.0042
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Onchocerca volvulus 0.0305 0.0551 0.4594
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0092 0.0135 0.0135
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.004 0.0243
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Schistosoma mansoni cript-related 0.0024 0.0001 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0955 0.1823 1
Echinococcus granulosus expressed protein 0.0066 0.0083 0.009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Leishmania major histone deacetylase, putative 0.0344 0.0627 0.3436
Echinococcus multilocularis histone deacetylase 3 0.0297 0.0535 0.0535
Brugia malayi Muscleblind-like protein 0.08 0.152 0.2074
Entamoeba histolytica hypothetical protein 0.0098 0.0145 0.0386
Entamoeba histolytica protein kinase, putative 0.0098 0.0145 0.0386
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.004 0.0031 0.0154
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0273 0.0488 0.1447
Echinococcus granulosus heat shock protein 90 0.0065 0.0081 0.0088
Toxoplasma gondii cytochrome p450 superfamily protein 0.0046 0.0043 0.0261
Echinococcus multilocularis cysteine protease 0.0035 0.0022 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.012 0.0188 0.0502
Brugia malayi kinase, mitochondrial precursor 0.004 0.0031 0.0042
Plasmodium falciparum acyl-CoA synthetase 0.0112 0.0172 0.106
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0037 0.004
Echinococcus granulosus histone deacetylase 6 0.0359 0.0656 0.0717
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0034 0.0037
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0044 0.0044
Trichomonas vaginalis esterase, putative 0.0273 0.0488 0.1305
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0037 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0081 0.0111 0.0152
Leishmania major DNA polymerase kappa, putative 0.0037 0.0026 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0138
Mycobacterium tuberculosis Probable two component sensor kinase 0.004 0.0031 0.009
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.004 0.0031 0.0154
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0028 0.0234
Echinococcus multilocularis musashi 0.0174 0.0295 0.0295
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0637 0.12 0.321
Onchocerca volvulus 0.0273 0.0488 0.407
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0119 0.0188 0.0256
Echinococcus multilocularis sodium channel protein 0.0036 0.0025 0.0025
Echinococcus granulosus neuroligin 0.0637 0.12 0.1311
Echinococcus multilocularis nmda type glutamate receptor 0.1482 0.2854 0.2854
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0048 0.0065
Toxoplasma gondii DNA topoisomerase family protein 0.0034 0.0021 0.0123
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0235 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.085 0.1617 0.8867
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0099 0.0108
Leishmania major hypothetical protein, conserved 0.004 0.0031 0.0166
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0044 0.0039 0.0054
Onchocerca volvulus 0.0024 0.0001 0.0007
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Trypanosoma brucei developmentally regulated phosphoprotein 0.004 0.0031 0.0166
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0081 0.0111 0.0122
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.004 0.0031 0.0166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0188 0.05
Mycobacterium tuberculosis Possible two component sensor kinase 0.004 0.0031 0.009
Loa Loa (eye worm) heat shock protein 90 0.0065 0.0081 0.011
Loa Loa (eye worm) hypothetical protein 0.0132 0.0213 0.029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0081 0.0111 0.0122
Mycobacterium tuberculosis Carboxylesterase LipT 0.0637 0.12 0.3559
Echinococcus granulosus GPCR family 2 0.0115 0.0179 0.0195
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0028 0.0234
Brugia malayi hypothetical protein 0.0052 0.0056 0.0077
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Plasmodium vivax telomerase reverse transcriptase, putative 0.057 0.107 0.6618
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Mycobacterium tuberculosis Probable reductase 0.0105 0.0159 0.0471
Brugia malayi latrophilin 2 splice variant baaae 0.0248 0.044 0.06
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0131 0.0143
Mycobacterium leprae Probable lipase LipE 0.0273 0.0488 0.2697
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Brugia malayi Bromodomain containing protein 0.0044 0.004 0.0054
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0046 0.0043 0.022
Plasmodium vivax topoisomerase I, putative 0.085 0.1617 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0018 0.0105
Giardia lamblia DNA repair protein RAD52 0.1174 0.2251 0.6024
Loa Loa (eye worm) hypothetical protein 0.0305 0.0551 0.0752
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Echinococcus multilocularis muscleblind protein 1 0.08 0.152 0.152
Brugia malayi jmjC domain containing protein 0.0091 0.0131 0.0179
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0037 0.0096
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0044 0.0039 0.0103
Echinococcus granulosus transcription factor btf3 0.0039 0.003 0.0032
Echinococcus granulosus synaptojanin 1 0.0024 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Leishmania major DNA polymerase eta, putative 0.0064 0.0079 0.0429
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.009 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Leishmania major mitochondrial DNA topoisomerase II 0.072 0.1362 0.747
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Leishmania major DNA polymerase eta, putative 0.0147 0.0241 0.1317
Trypanosoma brucei DNA polymerase eta, putative 0.0147 0.0241 0.1317
Onchocerca volvulus 0.0637 0.12 1
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0028 0.0038
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0955 0.1823 1
Schistosoma mansoni heat shock protein 0.0065 0.0081 0.0088
Schistosoma mansoni cell polarity protein 0.0142 0.0232 0.0253
Loa Loa (eye worm) hypothetical protein 0.0066 0.0083 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0081 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Giardia lamblia DNA topoisomerase II 0.0602 0.1132 0.3029
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0039 0.0029 0.0156
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0029 0.0011 0.0056
Echinococcus granulosus glutamate receptor 2 0.0234 0.0412 0.0451
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Schistosoma mansoni inositol monophosphatase 0.0159 0.0265 0.029
Onchocerca volvulus 0.0034 0.0021 0.0173
Entamoeba histolytica hypothetical protein 0.0079 0.0109 0.029
Brugia malayi steroid hormone receptor 0.0081 0.0111 0.0152
Echinococcus multilocularis ecdysone induced protein 78C 0.0081 0.0111 0.0111
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0098 0.0145 0.0791
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.0522 0.057
Toxoplasma gondii RNA-directed DNA polymerase 0.0092 0.0134 0.0824
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0112 0.069
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0046 0.0043 0.022
Brugia malayi nuclear receptor RXR 0.0043 0.0037 0.005
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0637 0.12 0.1311
Trypanosoma brucei protein kinase, putative 0.006 0.0071 0.0385
Loa Loa (eye worm) hypothetical protein 0.0242 0.0427 0.0583
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0155 0.017
Mycobacterium ulcerans DNA gyrase subunit B 0.0377 0.0692 0.3826
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) glutaminase 2 0.0291 0.0524 0.0715
Brugia malayi nuclear hormone receptor 0.0081 0.0111 0.0152
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0037 0.0221
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0018 0.0093
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Brugia malayi CHE-14 protein 0.0043 0.0038 0.0052
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Mycobacterium ulcerans DNA gyrase subunit A 0.0137 0.0221 0.121
Loa Loa (eye worm) STAT protein 0.0154 0.0255 0.0347
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0042 0.0037 0.0037
Mycobacterium ulcerans DNA polymerase IV 0.0148 0.0243 0.1333
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0044 0.006
Brugia malayi Cytochrome P450 family protein 0.0064 0.0079 0.0108
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0028 0.0028
Echinococcus granulosus acetylcholinesterase 0.3769 0.733 0.8009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0437
Giardia lamblia Fructose-bisphosphate aldolase 0.1933 0.3737 1
Brugia malayi histone deacetylase 1 (HD1) 0.0297 0.0535 0.073
Brugia malayi Doublecortin family protein 0.0066 0.0083 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi nuclear receptor NHR-88 0.0038 0.0028 0.0038
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0081 0.0111 0.0122
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0081 0.044
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.01 0.01
Loa Loa (eye worm) latrophilin receptor protein 2 0.0115 0.0179 0.0244
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0082 0.009
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0112 0.0172 0.0508
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0116 0.018 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0046 0.0043 0.0125
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Leishmania major DNA topoisomerase 1A 0.0034 0.0021 0.0109
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Schistosoma mansoni lipoxygenase 0.0066 0.0083 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0028 0.0073
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0018 0.0018
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.029 0.0522 0.0712
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0397 0.0731 0.4045
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Loa Loa (eye worm) glutaminase 0.0291 0.0524 0.0715
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0159 0.0265 0.0707
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0046 0.0043 0.0125
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0009 0.0012
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.003 0.0012 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0028 0.0038
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0092 0.0135 0.0135
Schistosoma mansoni ap endonuclease 0.0119 0.0188 0.0205
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0066 0.009
Brugia malayi STAT protein, DNA binding domain containing protein 0.0154 0.0255 0.0347
Schistosoma mansoni hypothetical protein 0.0036 0.0025 0.0027
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0032 0.0032
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Mycobacterium ulcerans glutaminase 0.0291 0.0524 0.2893
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0034 0.0021 0.0028
Leishmania major DNA polymerase kappa, putative 0.0127 0.0202 0.1103
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0081 0.0111 0.0152
Brugia malayi ThiF family protein 0.0052 0.0055 0.0075
Schistosoma mansoni rotamase 0.0066 0.0083 0.009
Trichomonas vaginalis hypothetical protein 0.0044 0.004 0.0105
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0363 0.0665 0.0907
Brugia malayi jmjC domain containing protein 0.0068 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.012 0.0188 0.0257
Echinococcus multilocularis glutamate receptor 2 0.0155 0.0257 0.0257
Toxoplasma gondii histone deacetylase HDAC2 0.0297 0.0535 0.3304
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Trypanosoma brucei DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Schistosoma mansoni hypothetical protein 0.0056 0.0063 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0047 0.0046 0.005
Loa Loa (eye worm) hypothetical protein 0.0366 0.067 0.0914
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0246 0.0656
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0081 0.0111 0.0152
Trypanosoma brucei DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Brugia malayi isocitrate dehydrogenase 0.0033 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0944 0.1802 1
Onchocerca volvulus 0.0637 0.12 1
Entamoeba histolytica protein kinase, putative 0.0098 0.0145 0.0386
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.004 0.0031 0.0081
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0115 0.0178 0.0194
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0081 0.0111 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.004 0.0031 0.0154
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0012 0.003
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0155 0.0212
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0034 0.002 0.0121
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0044 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0048 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0046 0.0043 0.0125
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0363 0.0665 0.0907
Plasmodium falciparum glutathione reductase 0.0046 0.0044 0.0266
Plasmodium vivax SET domain protein, putative 0.0041 0.0034 0.0207
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Loa Loa (eye worm) hypothetical protein 0.3769 0.733 1
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0026 0.0141
Loa Loa (eye worm) glutamate receptor 2 0.0155 0.0257 0.035
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0048 0.0256
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0081 0.0111 0.0111
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Loa Loa (eye worm) histone deacetylase 11 0.0242 0.0427 0.0583
Onchocerca volvulus 0.0174 0.0295 0.2457
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.008 0.011 0.0293
Loa Loa (eye worm) hypothetical protein 0.0046 0.0044 0.006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0028 0.0031
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0028 0.0038
Echinococcus multilocularis GPCR, family 2 0.0115 0.0179 0.0179
Brugia malayi MH2 domain containing protein 0.0253 0.0449 0.0612
Echinococcus granulosus histone deacetylase 7 0.0344 0.0627 0.0685
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0155 0.0257 0.0257
Trypanosoma brucei histone deacetylase 3 0.0344 0.0627 0.3436
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.004 0.0105
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0188 0.1155
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0008 0.002
Schistosoma mansoni histone deacetylase 4 5 0.0344 0.0627 0.0685
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0141
Schistosoma mansoni hypothetical protein 0.4699 0.9152 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Plasmodium falciparum telomerase reverse transcriptase 0.057 0.107 0.6618
Leishmania major C-8 sterol isomerase-like protein 0.0396 0.0729 0.3994
Mycobacterium ulcerans hypothetical protein 0.0037 0.0026 0.0128
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Schistosoma mansoni lipoxygenase 0.0185 0.0317 0.0346
Onchocerca volvulus 0.0035 0.0022 0.0179
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0034 0.0034
Echinococcus multilocularis expressed protein 0.0066 0.0083 0.0083
Toxoplasma gondii hypothetical protein 0.0052 0.0055 0.0336
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0112 0.069
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0025 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0079
Treponema pallidum chemotaxis histidine kinase (cheA) 0.004 0.0031 0.0081
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Trypanosoma brucei DNA topoisomerase ii 0.072 0.1362 0.747
Trichomonas vaginalis penicillin-binding protein, putative 0.0273 0.0488 0.1305
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0048 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Schistosoma mansoni alpha-glucosidase 0.031 0.0561 0.0613
Leishmania major trypanothione reductase 0.0046 0.0044 0.0236
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.0111 0.0152
Plasmodium falciparum histone deacetylase 2 0.0344 0.0627 0.3875
Toxoplasma gondii DNA topoisomerase I, putative 0.085 0.1617 1
Schistosoma mansoni tyrosine kinase 0.0079 0.0109 0.0119
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0134 0.0217 0.1183
Mycobacterium tuberculosis Cell division protein FtsZ 0.0326 0.0591 0.1752
Mycobacterium ulcerans beta-lactamase 0.0273 0.0488 0.2697
Trypanosoma brucei glycosyl hydrolase-like protein 0.003 0.0012 0.0061
Schistosoma mansoni cpg binding protein 0.0363 0.0664 0.0725
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0273 0.0488 0.1447
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0035 0.0023 0.012
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0008 0.0012
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0028 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0131 0.0179
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0044 0.0039 0.02
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0081 0.0111 0.0152
Echinococcus granulosus glutamate receptor 2 0.0079 0.0109 0.0119
Echinococcus multilocularis conserved hypothetical protein 0.0742 0.1406 0.1406
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Trypanosoma brucei Vps23 core domain containing protein, putative 0.007 0.0091 0.0496
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Leishmania major hypothetical protein, conserved 0.0273 0.0488 0.2675
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0052
Plasmodium vivax heat shock protein 86, putative 0.0065 0.0081 0.0496
Loa Loa (eye worm) endoplasmin 0.0065 0.0081 0.011
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0028 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.0115 0.0179 0.0245
Echinococcus granulosus bloom syndrome protein 0.0042 0.0037 0.004
Echinococcus granulosus single minded 2 0.0081 0.0112 0.0122
Brugia malayi tailless protein 0.0038 0.0028 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Treponema pallidum heat shock protein 90 0.0025 0.0003 0.0007
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.004 0.0031 0.0188
Toxoplasma gondii cathepsin CPL 0.0035 0.0022 0.0128
Echinococcus granulosus glutamate NMDA receptor subunit 0.0155 0.0257 0.0281
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0079 0.0429
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0071 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0022 0.0022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0115 0.0178 0.0178
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0008 0.002
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0143 0.0156
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0437
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0022 0.0128
Onchocerca volvulus 0.0035 0.0022 0.0179
Brugia malayi Steroid receptor seven-up type 2 0.0081 0.0111 0.0152
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0048 0.0256
Echinococcus multilocularis Polycystic kidney disease protein 0.0066 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0155 0.0257 0.0281
Brugia malayi Glycosyl hydrolases family 31 protein 0.008 0.011 0.015
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0048 0.0125
Loa Loa (eye worm) histone deacetylase 1 0.0297 0.0535 0.073
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0116 0.018 0.0983
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0028 0.0031
Schistosoma mansoni nuclear receptor 0.0038 0.0028 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.072 0.1362 0.747
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.0039 0.02
Schistosoma mansoni cpg binding protein 0.0386 0.0709 0.0774
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Plasmodium falciparum histone deacetylase, putative 0.0344 0.0627 0.3875
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0039 0.0029 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0503 0.0938 0.2783
Onchocerca volvulus 0.0273 0.0488 0.407
Echinococcus multilocularis acetylcholinesterase 0.3769 0.733 0.733
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0449 0.0612
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0141
Plasmodium falciparum flap endonuclease 1 0.0028 0.0008 0.0047
Plasmodium falciparum histone deacetylase 1 0.0297 0.0535 0.3304
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0028 0.0009 0.0022
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Onchocerca volvulus 0.0081 0.0111 0.0928
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0034 0.002 0.0107
Trichomonas vaginalis adenylate cyclase, putative 0.0028 0.0009 0.0022
Trichomonas vaginalis sucrase-isomaltase, putative 0.008 0.011 0.0293
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0944 0.1802 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.0522 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.004 0.0031 0.0154
Treponema pallidum cell division protein FtsZ 0.0326 0.0591 0.158
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0046
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0046 0.0043 0.022
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.1994 0.3857 0.5263
Loa Loa (eye worm) DnaJ domain-containing protein 0.007 0.0092 0.0125
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0111 0.0172 0.0188
Mycobacterium tuberculosis Conserved protein 0.004 0.0031 0.009
Echinococcus multilocularis rho GTPase activating protein 20 0.0034 0.0021 0.0021
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0174 0.0295 0.0402
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Echinococcus multilocularis cysteine protease 0.0035 0.0022 0.0022
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0052 0.0055 0.006
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Trypanosoma cruzi Heat shock protein 83, putative 0.0065 0.0081 0.044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0115 0.0179 0.0195
Echinococcus multilocularis glutamate receptor NMDA 0.1402 0.2698 0.2698
Loa Loa (eye worm) acetylcholinesterase 1 0.3769 0.733 1
Schistosoma mansoni ATP-binding cassette transporter 0.0155 0.0257 0.0281
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Brugia malayi Thioredoxin reductase 0.0046 0.0044 0.006
Plasmodium falciparum DNA topoisomerase 2 0.0642 0.121 0.7482
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0116 0.018 0.018
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0052 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Loa Loa (eye worm) histone deacetylase 7A 0.0344 0.0627 0.0855
Loa Loa (eye worm) hypothetical protein 0.0101 0.0151 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0081 0.0111 0.0152
Mycobacterium tuberculosis Two component sensor kinase MprB 0.004 0.0031 0.009
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.072 0.1362 0.747
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.007 0.0091 0.0496
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Loa Loa (eye worm) hypothetical protein 0.0052 0.0055 0.0075
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0044 0.0039 0.02
Echinococcus granulosus endoplasmin 0.0025 0.0003 0.0004
Onchocerca volvulus 0.0066 0.0083 0.0694
Echinococcus granulosus atrial natriuretic peptide receptor 0.0079 0.0109 0.0119
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0022 0.0023
Brugia malayi Histone deacetylase family protein 0.0344 0.0627 0.0855
Onchocerca volvulus 0.0079 0.0109 0.0909
Onchocerca volvulus Protein ultraspiracle homolog 0.0081 0.0111 0.0928
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0089 0.0129 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Trypanosoma cruzi histone deacetylase 1, putative 0.0297 0.0535 0.293
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.008 0.0433
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0034 0.002 0.002
Echinococcus granulosus ecdysone induced protein 78C 0.0081 0.0111 0.0122
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0048 0.0065
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0217 0.0296
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.003 0.0077
Echinococcus multilocularis lysosomal alpha glucosidase 0.0361 0.0659 0.0659
Brugia malayi Melibiase family protein 0.0074 0.0099 0.0135
Onchocerca volvulus 0.0066 0.0083 0.0694
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0273 0.0488 0.0666
Giardia lamblia Grp94/Hsp90 0.0025 0.0003 0.0007
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.008 0.011 0.0293
Echinococcus granulosus histone deacetylase 6 0.0344 0.0627 0.0685
Echinococcus granulosus sentrin specific protease 8 0.0071 0.0093 0.0102
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0234 0.0412 0.0412
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0044 0.0128
Onchocerca volvulus 0.0097 0.0143 0.1193
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0018 0.0105
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0642 0.121 0.1651
Schistosoma mansoni histone deacetylase 0.0297 0.0535 0.0584
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Brugia malayi GRF zinc finger family protein 0.0034 0.0021 0.0028
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0048 0.0256
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0155 0.1295
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) glutamate receptor 0.0079 0.0109 0.0149
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0071 0.0188
Schistosoma mansoni myst-related protein 0.0045 0.0042 0.0046
Brugia malayi Pre-SET motif family protein 0.0041 0.0034 0.0047
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0039 0.0029 0.0076
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Echinococcus granulosus glutamate receptor subunit protein glur 0.0155 0.0257 0.0281
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0024 0.0001 0.0001
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0234 0.0412 0.0451
Brugia malayi nuclear receptor NHR-88 0.0081 0.0111 0.0152
Trypanosoma brucei histone deacetylase 2 0.0242 0.0427 0.234
Plasmodium vivax DNA topoisomerase 3, putative 0.0034 0.0021 0.0123
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.008 0.0433
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0071 0.0078
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0137 0.0221 0.3163
Brugia malayi MAP kinase sur-1 0.006 0.0071 0.0097
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.008 0.011 0.0293
Echinococcus multilocularis NMDA receptor 0.0155 0.0257 0.0257
Brugia malayi Guanylyl cyclase protein 23 0.0079 0.0109 0.0149
Schistosoma mansoni synaptojanin 0.0024 0.0001 0.0001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0034 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0081 0.0111 0.0152
Schistosoma mansoni rab6-interacting 0.0066 0.0083 0.0091
Onchocerca volvulus 0.0041 0.0034 0.0285
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Echinococcus granulosus neutral sphingomyelinase 0.0024 0.0001 0.0001
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0044 0.0266
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0048 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Onchocerca volvulus 0.0035 0.0022 0.0179
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1933 0.3737 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0009 0.0009
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0127 0.0202 0.1103
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.0317 0.0317
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0154 0.0168
Brugia malayi beta-lactamase family protein 0.0273 0.0488 0.0666
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0083 0.0219
Onchocerca volvulus Bile acid receptor homolog 0.0081 0.0111 0.0928
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Plasmodium vivax vivapain-2 0.0035 0.0022 0.0128
Onchocerca volvulus Huntingtin homolog 0.0257 0.0457 0.3804
Loa Loa (eye worm) hypothetical protein 0.08 0.152 0.2074
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0034 0.0021 0.0123
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.023 0.1255
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0217 0.0217
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0046 0.0043 0.022
Giardia lamblia DNA topoisomerase III 0.0034 0.0021 0.0053
Schistosoma mansoni single-minded 0.0109 0.0167 0.0183
Loa Loa (eye worm) hypothetical protein 0.0257 0.0457 0.0623
Echinococcus granulosus metabotropic glutamate receptor 2 0.0079 0.0109 0.0119
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0394 0.0724 0.6033
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0028 0.0031
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0276 0.0495 0.0541
Echinococcus granulosus hypothetical protein 0.0766 0.1453 0.1587
Echinococcus multilocularis tumor protein p63 0.0661 0.1248 0.1248
Loa Loa (eye worm) hypothetical protein 0.0132 0.0213 0.029
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0084 0.0118 0.0129
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0112 0.0612
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0145 0.0386
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0155 0.0257 0.0281
Echinococcus granulosus transcription factor Dp 1 0.004 0.0032 0.0035
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0044 0.0039 0.0115
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0048 0.0048
Echinococcus multilocularis lamin dm0 0.0174 0.0295 0.0295
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0028 0.0031
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Schistosoma mansoni cpg binding protein 0.0386 0.0709 0.0774
Echinococcus granulosus heat shock protein 90 0.0025 0.0003 0.0004
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0027 0.0007 0.0015
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0079 0.0109 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0188 0.05
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0044 0.0039 0.0115
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0039 0.0029 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0046 0.0043 0.0125
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1174 0.2251 0.6024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Leishmania major DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Trypanosoma cruzi hypothetical protein 0.0071 0.0093 0.0508
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0075 0.01 0.0137
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0377 0.0692 0.205
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0022 0.0029
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0082 0.0446
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Brugia malayi metabotropic glutamate receptor type 2 0.0079 0.0109 0.0149
Loa Loa (eye worm) glutamate receptor 1 0.0155 0.0257 0.035
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Mycobacterium ulcerans carboxylesterase, LipT 0.0637 0.12 0.6653
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0081 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0046 0.0043 0.0125
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0044 0.0039 0.02
Schistosoma mansoni hypothetical protein 0.1605 0.3095 0.3382
Echinococcus multilocularis dnaJ subfamily B 0.4699 0.9152 0.9152
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0026 0.0141
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0048 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0138
Leishmania major cytochrome p450-like protein 0.0103 0.0155 0.0849
Leishmania major histone deacetylase, putative 0.0297 0.0535 0.293
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0073 0.0073
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0098 0.0145 0.0198
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.02
Leishmania major hypothetical protein, conserved 0.007 0.0091 0.0496
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0243 0.1329
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0042 0.0037 0.004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0012 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0081 0.0111 0.0122
Brugia malayi Probable DNA topoisomerase II 0.0642 0.121 0.1651
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.0037 0.004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0037 0.005
Brugia malayi Histone deacetylase 1 0.0297 0.0535 0.073
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0131 0.0143
Schistosoma mansoni DNA topoisomerase II 0.0642 0.121 0.1322
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0046 0.0043 0.0125
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0038 0.0028 0.0038
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0188 0.1155
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.011 0.06
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0048 0.0065
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.012 0.0188 0.0206
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0273 0.0488 0.0534
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0071 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0034 0.002 0.0107
Trichomonas vaginalis set domain proteins, putative 0.0264 0.047 0.1256
Chlamydia trachomatis DNA gyrase subunit B 0.0377 0.0692 0.9425
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0022 0.0179
Trichomonas vaginalis spcc417.12 protein, putative 0.0637 0.12 0.321
Brugia malayi hypothetical protein 0.0366 0.067 0.0914
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0039 0.0029 0.004
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Brugia malayi conserved hypotetical protein 0.0038 0.0028 0.0038
Echinococcus multilocularis carboxylesterase 5A 0.3769 0.733 0.733
Brugia malayi polk-prov protein 0.0065 0.0081 0.0111
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0036 0.0025 0.0131
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0165 0.0277 0.152
Onchocerca volvulus 0.0079 0.0109 0.0909
Echinococcus granulosus geminin 0.1605 0.3095 0.3382
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.009 0.0122
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.022 0.0384 0.0384
Brugia malayi Carboxylesterase family protein 0.3769 0.733 1
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0052 0.0055 0.0336
Treponema pallidum DNA topoisomerase I (topA) 0.0034 0.0021 0.0053
Brugia malayi Histone deacetylase family protein 0.0344 0.0627 0.0855
Trypanosoma cruzi cytochrome P450, putative 0.0103 0.0155 0.0849
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0019
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0081 0.0111 0.0152
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0071 0.0385
Leishmania major protein kinase, putative 0.0039 0.0029 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0055 0.0299
Loa Loa (eye worm) fibroinase 0.0035 0.0022 0.0029
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0064 0.008 0.0433
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0079 0.0109 0.0109
Echinococcus multilocularis histone deacetylase 1 0.0297 0.0535 0.0535
Echinococcus granulosus dnaJ subfamily B 0.4699 0.9152 1
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.003 0.0158
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Echinococcus multilocularis glutamate receptor 2 0.0079 0.0109 0.0109
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Echinococcus granulosus intermediate filament protein 0.0174 0.0295 0.0322
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0155 0.0257 0.0281
Plasmodium vivax hypothetical protein, conserved 0.004 0.0031 0.0188
Onchocerca volvulus 0.0035 0.0022 0.0179
Trichomonas vaginalis helicase, putative 0.0082 0.0115 0.0304
Echinococcus granulosus lamin 0.0174 0.0295 0.0322
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0159 0.0265 0.0707
Brugia malayi Metabotropic glutamate receptor precursor. 0.0079 0.0109 0.0149
Echinococcus granulosus carboxylesterase 5A 0.3769 0.733 0.8009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0103 0.0155 0.0846
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0396 0.0729 0.0994
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0041 0.0034 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0034 0.0037
Schistosoma mansoni DNA helicase recq5 0.0042 0.0037 0.004
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0046 0.0043 0.0125
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0046 0.0043 0.022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0119 0.0188 0.1024
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0149 0.0246 0.1349
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.0221
Echinococcus multilocularis tyrosine kinase 0.0079 0.0109 0.0109
Entamoeba histolytica hypothetical protein 0.0045 0.0042 0.0109
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.009 0.0122
Loa Loa (eye worm) hypothetical protein 0.0115 0.0179 0.0244
Echinococcus granulosus BC026374 protein S09 family 0.0637 0.12 0.1311
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0022 0.0113
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Brugia malayi Cell division protein ftsZ 0.0161 0.0268 0.0366
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0157 0.0856
Onchocerca volvulus 0.0033 0.0019 0.0154
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0034 0.0021 0.0021
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0112 0.0173 0.0462
Mycobacterium ulcerans hypothetical protein 0.0273 0.0488 0.2697
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0159 0.0868
Brugia malayi exodeoxyribonuclease III family protein 0.0119 0.0188 0.0256
Loa Loa (eye worm) glutathione reductase 0.0046 0.0044 0.006
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0046 0.0043 0.0125
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0018 0.0093
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0246 0.1349
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0137 0.0221 0.0589
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0028 0.0031
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0022 0.0023
Plasmodium falciparum protein kinase 5 0.0048 0.0048 0.0289
Echinococcus multilocularis dual specificity 0.0098 0.0145 0.0145
Leishmania major basic transcription factor 3a, putative 0.0039 0.003 0.0158
Toxoplasma gondii histone deacetylase HDAC3 0.0297 0.0535 0.3304
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0064 0.008 0.0433
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Onchocerca volvulus 0.0028 0.0009 0.0076
Plasmodium falciparum DNA repair protein REV1, putative 0.0037 0.0026 0.0159
Echinococcus granulosus lysosomal alpha glucosidase 0.0361 0.0659 0.0721
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0028 0.0028
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0155 0.0155
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0046 0.0043 0.0125
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.0012 0.0016
Loa Loa (eye worm) histone deacetylase 3 0.0297 0.0535 0.073
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0099 0.0108
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.004 0.0031 0.009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0246 0.1349
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0082 0.0082
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0022 0.0179
Brugia malayi GTP-binding protein 0.0142 0.0232 0.0316
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0159 0.0265 0.3803
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.0522 0.0522
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0246 0.0656
Schistosoma mansoni histone deacetylase hda2 0.0359 0.0656 0.0717
Leishmania major ubiquitin-activating enzyme-like protein 0.0034 0.002 0.0107
Onchocerca volvulus Putative neutral sphingomyelinase 0.0024 0.0001 0.0007
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Brugia malayi CXXC zinc finger family protein 0.0363 0.0664 0.0906
Leishmania major hypothetical protein, conserved 0.0081 0.0112 0.0612
Trichomonas vaginalis maltase-glucoamylase, putative 0.008 0.011 0.0293
Plasmodium vivax histone deacetylase 1, putative 0.0297 0.0535 0.3304
Leishmania major developmentally regulated phosphoprotein-like protein 0.004 0.0031 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0092 0.0135 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Plasmodium vivax acetyl-CoA synthetase, putative 0.0044 0.0039 0.0239
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0034 0.002 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0134 0.0183
Schistosoma mansoni tsg101-related 0.0183 0.0312 0.0341
Echinococcus granulosus glutamate receptor NMDA 0.1402 0.2698 0.2948
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.004 0.0031 0.009
Mycobacterium ulcerans putative regulatory protein 0.0081 0.0112 0.0602
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0119 0.0188 0.05
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Schistosoma mansoni zinc finger protein 0.0043 0.0038 0.0042
Schistosoma mansoni alpha glucosidase 0.008 0.011 0.012
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0119 0.0188 0.2675
Echinococcus multilocularis zinc finger protein 0.0043 0.0038 0.0038
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0159 0.0471
Schistosoma mansoni tsg101-related 0.0149 0.0246 0.0269
Plasmodium falciparum DNA gyrase subunit A 0.0137 0.0221 0.1363
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0022 0.0055
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0093 0.0136 0.0186
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0028 0.0028
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0092 0.0134 0.0356
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0086 0.0094
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0071 0.0385
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0079 0.0109 0.0109
Echinococcus multilocularis RUN 0.0066 0.0083 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0079
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0608 0.1143 0.6267
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0071 0.0071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0028 0.0073
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Mycobacterium ulcerans hypothetical protein 0.0503 0.0938 0.5199
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0159 0.0265 0.0707
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0022 0.0179
Brugia malayi ImpB/MucB/SamB family protein 0.0147 0.0241 0.0329
Echinococcus granulosus FTZ F1 alpha 0.0081 0.0111 0.0122
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0038 0.0042
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0137 0.0221 0.1363
Trypanosoma brucei unspecified product 0.0083 0.0116 0.0629
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.004 0.0031 0.009
Brugia malayi hypothetical protein 0.0148 0.0244 0.0332
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0034 0.0021 0.0023
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.004 0.0031 0.0154
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0044 0.0039 0.0115
Loa Loa (eye worm) DR-78 0.0038 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Brugia malayi Inositol-1 0.0159 0.0265 0.0362
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0116 0.018 0.048
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0044 0.0039 0.0239
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Mycobacterium leprae Probable two-component sensor kinase 0.004 0.0031 0.0154
Entamoeba histolytica acyl-coA synthetase, putative 0.0149 0.0246 0.0656
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.009 0.0098
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0115 0.0179 0.0179
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.005
Trypanosoma cruzi DNA topoisomerase II, putative 0.0608 0.1143 0.6267
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0046 0.0043 0.0231
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0081 0.0441
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0046 0.0043 0.022
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0034 0.0021 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0081 0.0111 0.0152
Entamoeba histolytica DNA topoisomerase II, putative 0.0642 0.121 0.3236
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.004 0.0031 0.0188
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0081 0.0111 0.0111
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0044 0.0039 0.0239
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Schistosoma mansoni inositol monophosphatase 0.0159 0.0265 0.029
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Giardia lamblia DNA damage repair protein 0.0037 0.0026 0.0069
Brugia malayi intermediate filament protein 0.0174 0.0295 0.0402
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0052 0.0055 0.006
Schistosoma mansoni SET domain protein 0.0044 0.0039 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Loa Loa (eye worm) carboxylesterase 0.0637 0.12 0.1637
Entamoeba histolytica hypothetical protein 0.0039 0.003 0.0077
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0042 0.0037 0.0037
Trypanosoma brucei C-8 sterol isomerase, putative 0.0396 0.0729 0.3994
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0028 0.0031
Brugia malayi Cytochrome P450 family protein 0.0046 0.0043 0.0059
Loa Loa (eye worm) oxidoreductase 0.0044 0.0039 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0112 0.069
Brugia malayi ThiF family protein 0.0034 0.002 0.0028
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.004 0.0031 0.0166
Mycobacterium ulcerans acetyl-CoA synthetase 0.0044 0.0039 0.02
Echinococcus granulosus zinc finger protein 0.0043 0.0038 0.0042
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0046 0.0043 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0081 0.0111 0.0152
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0012 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0081 0.0111 0.0122
Schistosoma mansoni nuclear hormone receptor 0.0081 0.0111 0.0122
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Loa Loa (eye worm) hypothetical protein 0.0171 0.0289 0.0394
Mycobacterium ulcerans DNA polymerase IV 0.0148 0.0243 0.1333
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.0488 0.2675
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Giardia lamblia Sgs1 DNA helicase, putative 0.0042 0.0037 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0026 0.0066
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0156
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0028 0.0028
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0119 0.0188 0.0554
Brugia malayi histone deacetylase 3 (HD3) 0.0297 0.0535 0.073
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0081 0.0111 0.0122
Loa Loa (eye worm) TOPoisomerase family member 0.0642 0.121 0.1651
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0772 0.1465 0.16
Mycobacterium tuberculosis Probable lipase LipE 0.0273 0.0488 0.1447
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Onchocerca volvulus 0.0174 0.0295 0.2457
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.004 0.0031 0.0188
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Brugia malayi beta-lactamase family protein 0.0273 0.0488 0.0666
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0038 0.0052
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.3769 0.733 0.8009
Onchocerca volvulus 0.0044 0.0039 0.0329
Brugia malayi GTP-binding protein, identical 0.0142 0.0232 0.0316
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0038 0.0028 0.0079
Echinococcus multilocularis traf and tnf receptor associated protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) ctsf protein 0.0035 0.0022 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0016
Echinococcus multilocularis muscleblind protein 0.08 0.152 0.152
Echinococcus multilocularis histone deacetylase 8 0.0242 0.0427 0.0427
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0003 0.0014
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.004 0.0031 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0119 0.0188 0.1024
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0075 0.01 0.0137
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0044 0.0039 0.0115
Trichomonas vaginalis hypothetical protein 0.0107 0.0163 0.0434
Echinococcus granulosus beta LACTamase domain containing family member 0.0273 0.0488 0.0534
Schistosoma mansoni histone deacetylase 1 2 3 0.0242 0.0427 0.0467
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0046 0.0043 0.022
Brugia malayi hypothetical protein 0.022 0.0384 0.0524
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0081 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Plasmodium vivax DNA topoisomerase II, putative 0.0642 0.121 0.7482
Echinococcus multilocularis sentrin specific protease 8 0.0071 0.0093 0.0093
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.004 0.0031 0.009
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Toxoplasma gondii peptidylprolyl isomerase 0.0064 0.008 0.0488
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Schistosoma mansoni microtubule-associated protein tau 0.455 0.8859 0.968
Brugia malayi beta-lactamase 0.0273 0.0488 0.0666
Trypanosoma brucei telomerase reverse transcriptase 0.0092 0.0134 0.073
Onchocerca volvulus 0.0637 0.12 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0068 0.0087 0.0591
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0037 0.0096
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Brugia malayi photoreceptor-specific nuclear receptor 0.0081 0.0111 0.0152
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0066 0.0083 0.0113
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0055 0.0145
Trypanosoma cruzi histone deacetylase, putative 0.0242 0.0427 0.234
Brugia malayi Carboxylesterase family protein 0.3769 0.733 1
Loa Loa (eye worm) hypothetical protein 0.007 0.009 0.0123
Brugia malayi hypothetical protein 0.0038 0.0028 0.0038
Echinococcus granulosus Polycystic kidney disease protein 0.0066 0.0083 0.0091
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.0039 0.02
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0081 0.0111 0.0152
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0044 0.0039 0.0115
Schistosoma mansoni kinase 0.0053 0.0058 0.0063
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0081 0.0111 0.0122
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.004 0.0031 0.0403
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0022 0.0128
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0089 0.0129 0.0129
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0086 0.0086
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0081 0.044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0028 0.0009 0.0022
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0024 0.0001 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0035 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0046 0.0043 0.0125
Loa Loa (eye worm) hypothetical protein 0.0102 0.0153 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0071 0.0078
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Toxoplasma gondii ABC1 family protein 0.0273 0.0488 0.3017
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0034 0.002 0.0022
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0082 0.009
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.085 0.1617 0.8867
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1745 0.337 1
Mycobacterium ulcerans lipase LipD 0.0273 0.0488 0.2697
Brugia malayi SET domain containing protein 0.0033 0.0019 0.0025
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0048 0.0052
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0127 0.0202 0.0597
Brugia malayi histone deacetylase 11 0.0242 0.0427 0.0583
Mycobacterium tuberculosis Conserved hypothetical protein 0.012 0.0188 0.0557
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.003 0.0178
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0608 0.1143 0.6267
Loa Loa (eye worm) histone methyltransferase 0.0115 0.0178 0.0243
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Schistosoma mansoni glutaminase 0.0291 0.0524 0.0572
Schistosoma mansoni carbon catabolite repressor protein 0.0024 0.0001 0.0001
Toxoplasma gondii heat shock protein HSP90 0.0065 0.0081 0.0496
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0642 0.121 0.1651
Echinococcus multilocularis synaptojanin 1 0.0024 0.0001 0.0001
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0018 0.0105
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0026 0.0141
Plasmodium vivax glutathione reductase, putative 0.0046 0.0044 0.0266
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0048 0.0052
Schistosoma mansoni terminal deoxycytidyl transferase 0.012 0.0188 0.0206
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0081 0.0214
Echinococcus multilocularis FTZ F1 alpha 0.0081 0.0111 0.0111
Chlamydia trachomatis DNA gyrase subunit A 0.0137 0.0221 0.2555
Brugia malayi Pre-SET motif family protein 0.0233 0.0409 0.0559
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0046 0.0043 0.022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.004 0.0105
Echinococcus granulosus dnaJ subfamily C 6 0.007 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0065 0.0081 0.0111
Leishmania major protein kinase, putative 0.003 0.0013 0.0065
Loa Loa (eye worm) hypothetical protein 0.0044 0.0039 0.0054
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0436 0.0807 0.6723
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.004 0.0031 0.009
Giardia lamblia DINP protein human, muc B family 0.0127 0.0202 0.0538
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0034 0.0021 0.0096
Plasmodium vivax DNA gyrase subunit B, putative 0.0377 0.0692 0.4274
Trichomonas vaginalis protein kinase inhibitor, putative 0.007 0.0092 0.0243
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0034 0.0021 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0081 0.0111 0.0152
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Echinococcus granulosus expressed conserved protein 0.0095 0.0139 0.0152
Trypanosoma brucei glucosidase, putative 0.008 0.011 0.06
Brugia malayi DnaJ domain containing protein 0.007 0.0092 0.0125
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0026 0.0159
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0044 0.0236
Loa Loa (eye worm) hypothetical protein 0.0276 0.0495 0.0675
Schistosoma mansoni metabotropic glutamate receptor 0.0079 0.0109 0.0119
Onchocerca volvulus Huntingtin homolog 0.0257 0.0457 0.3804
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0048 0.0256
Brugia malayi ImpB/MucB/SamB family protein 0.012 0.0188 0.0257
Trypanosoma cruzi extracellular receptor, putative 0.0079 0.0109 0.0594
Mycobacterium ulcerans DNA topoisomerase I 0.0034 0.0021 0.0096
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0048 0.0125
Echinococcus granulosus nmda type glutamate receptor 0.1954 0.3779 0.4129
Schistosoma mansoni neuroligin 3 (S09 family) 0.0637 0.12 0.1311
Echinococcus multilocularis BC026374 protein (S09 family) 0.0637 0.12 0.12
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0377 0.0692 0.4274
Leishmania major DNA damage repair protein, putative 0.0037 0.0026 0.0141
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.004 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.3769 0.733 1
Schistosoma mansoni lamin 0.0174 0.0295 0.0322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Brugia malayi cytoplasmic intermediate filament protein 0.0093 0.0136 0.0186
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Mycobacterium ulcerans epoxide hydrolase EphA 0.0317 0.0573 0.3169
Schistosoma mansoni histone deacetylase hda2 0.0242 0.0427 0.0467
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0149 0.0246 0.0657
Onchocerca volvulus 0.0273 0.0488 0.407
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0235 0.0257
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0066 0.0083 0.0113
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Loa Loa (eye worm) steroid hormone receptor 0.0081 0.0111 0.0152
Brugia malayi beta-NAC-like protein 0.0039 0.003 0.004
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0048 0.0256
Echinococcus multilocularis histone deacetylase 6 0.0359 0.0656 0.0656
Loa Loa (eye worm) hypothetical protein 0.0117 0.0183 0.0249
Echinococcus multilocularis receptor type guanylyl cyclase 0.0079 0.0109 0.0109
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0042 0.0037 0.004
Trichomonas vaginalis DNA topoisomerase II, putative 0.0642 0.121 0.3236
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0084 0.0118 0.0118
Brugia malayi Glutamate receptor 1 precursor 0.0155 0.0257 0.035
Loa Loa (eye worm) doublecortin family protein 0.0066 0.0083 0.0114
Brugia malayi hypothetical protein 0.1994 0.3857 0.5263
Mycobacterium ulcerans two component sensor kinase MprB 0.004 0.0031 0.0154
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.004 0.0031 0.009
Brugia malayi cell division control protein 2 homolog 0.0048 0.0048 0.0065
Schistosoma mansoni acetylcholinesterase 0.0637 0.12 0.1311
Mycobacterium leprae conserved hypothetical protein 0.0273 0.0488 0.2697
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0119 0.0188 0.1024
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0029
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0042 0.0037 0.005
Trypanosoma cruzi histone deacetylase 1, putative 0.0297 0.0535 0.293
Trypanosoma cruzi histone deacetylase, putative 0.0242 0.0427 0.234
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0452 0.0838 0.4596
Trichomonas vaginalis receptor histidine kinase, putative 0.004 0.0031 0.0081
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0048 0.0256
Mycobacterium ulcerans hypothetical protein 0.0149 0.0246 0.1349
Brugia malayi RNA binding protein 0.0135 0.0217 0.0296
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0159 0.0471
Brugia malayi follicle stimulating hormone receptor 0.052 0.0972 0.1326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0071 0.0385
Schistosoma mansoni cytochrome P450 0.0046 0.0043 0.0047
Echinococcus multilocularis beta LACTamase domain containing family member 0.0273 0.0488 0.0488
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0026 0.0066
Onchocerca volvulus 0.0081 0.0112 0.0931
Schistosoma mansoni thyroid hormone receptor 0.0081 0.0111 0.0122
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0092 0.0134 0.1116
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Giardia lamblia Pms1-like protein 0.004 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.0096 0.0141 0.0193
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0071 0.0385
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0046 0.0043 0.0231
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Brugia malayi Calcitonin receptor-like protein seb-1 0.0363 0.0665 0.0907
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0034 0.0021 0.0023
Schistosoma mansoni histone deacetylase 4 5 0.0344 0.0627 0.0685
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0046 0.0043 0.0125
Schistosoma mansoni intermediate filament proteins 0.0174 0.0295 0.0322
Onchocerca volvulus 0.0035 0.0022 0.0179
Plasmodium falciparum zinc finger protein, putative 0.0045 0.0042 0.0253
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0044 0.0039 0.0115
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0046 0.0043 0.0125
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0018 0.0019
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0034 0.0021 0.0053
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.0093 0.0248
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0637 0.12 0.3559
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0037 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0081 0.0111 0.0152
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0022 0.0029
Toxoplasma gondii melibiase subfamily protein 0.0111 0.0172 0.1058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.004 0.0031 0.0403
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.0221
Leishmania major glycosyl hydrolase-like protein 0.003 0.0012 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.0081 0.0111 0.0122
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis geminin 0.1605 0.3095 0.3095
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Leishmania major extracellular receptor, putative 0.0079 0.0109 0.0594
Giardia lamblia Heat shock protein HSP 90-alpha 0.0065 0.0081 0.0214
Echinococcus multilocularis heat shock protein 0.0065 0.0081 0.0081
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0003 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0046 0.0043 0.022
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0148 0.0244 0.0266
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0273 0.0488 0.2697
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0046 0.0043 0.0125
Echinococcus granulosus tyrosine kinase 0.0079 0.0109 0.0119
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0452 0.0838 0.4596
Echinococcus multilocularis para nitrobenzyl esterase 0.0637 0.12 0.12
Echinococcus multilocularis neuroligin 0.0637 0.12 0.12
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.004 0.0031 0.0081
Leishmania major cytochrome p450-like protein 0.0046 0.0043 0.0231
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0056 0.0063 0.0166
Plasmodium falciparum topoisomerase I 0.085 0.1617 1
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0436 0.0807 0.6723
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0071 0.0385
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Loa Loa (eye worm) hypothetical protein 0.0396 0.0729 0.0994
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0009 0.0022
Brugia malayi CCR4 0.0024 0.0001 0.0001
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0217 0.0296
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0397 0.0731 0.2167
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0111 0.0172 0.0172
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0046 0.0043 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Plasmodium falciparum thioredoxin reductase 0.0046 0.0044 0.0266
Schistosoma mansoni metabotropic glutamate receptor 0.0079 0.0109 0.0119
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.009 0.0098
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis Sentrin-specific protease, putative 0.0071 0.0093 0.0248
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0039 0.0029 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0081 0.0441
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0038 0.0042
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Schistosoma mansoni transcription factor LCR-F1 0.0148 0.0244 0.0266
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.019 0.1037
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0048 0.0052
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Echinococcus granulosus cathepsin l1 0.0035 0.0022 0.0023
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Trypanosoma brucei histone deacetylase, putative 0.0344 0.0627 0.3436
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0174 0.0295 0.0402
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0086 0.0094
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0046 0.0043 0.022
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0044 0.0039 0.0043
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.008 0.011 0.0293
Echinococcus multilocularis histone deacetylase 6 0.0344 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0047 0.0045 0.0062
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0112 0.0612
Loa Loa (eye worm) hypothetical protein 0.0248 0.044 0.06
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0151 0.0401
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0159 0.0471
Schistosoma mansoni DNA polymerase eta 0.0147 0.0241 0.0263
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0151 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Plasmodium vivax multidomain scavenger receptor, putative 0.0066 0.0083 0.051
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0182 0.0539
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Echinococcus multilocularis survival motor neuron protein 1 0.1994 0.3857 0.3857
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0047
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0149 0.0246 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0145 0.0158
Brugia malayi Cytochrome P450 family protein 0.0103 0.0155 0.0212
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0022 0.0128
Plasmodium vivax acyl-CoA synthetase, putative 0.0112 0.0172 0.106
Echinococcus granulosus RUN 0.0066 0.0083 0.0091
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.0012 0.003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0086 0.0252
Echinococcus multilocularis thyroid hormone receptor alpha 0.0081 0.0111 0.0111
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Onchocerca volvulus 0.0038 0.0028 0.0234
Onchocerca volvulus 0.0407 0.075 0.6249
Plasmodium falciparum DNA gyrase subunit B 0.0377 0.0692 0.4274
Leishmania major alpha glucosidase II subunit, putative 0.008 0.011 0.06
Echinococcus multilocularis inositol monophosphatase 1 0.0159 0.0265 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0363 0.0665 0.0907
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0023 0.0031
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Brugia malayi hypothetical protein 0.0257 0.0457 0.0623
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0083 0.0091
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0944 0.1802 0.5345
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Plasmodium vivax histone deacetylase, putative 0.0344 0.0627 0.3875
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0119 0.0188 0.05
Trichomonas vaginalis receptor histidine kinase, putative 0.004 0.0031 0.0081
Plasmodium falciparum LCCL domain-containing protein 0.0066 0.0083 0.051
Echinococcus multilocularis protein patched 0.0043 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Brugia malayi glutathione reductase 0.0046 0.0044 0.006
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.0045 0.0049
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0155 0.0212
Onchocerca volvulus 0.0637 0.12 1
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.003 0.0178
Brugia malayi cytochrome P450 0.0046 0.0043 0.0059

Activities

Activity type Activity value Assay description Source Reference
EC1000 (binding) = 2.6 nM Inhibition of HDAC4 assessed as induction of p21 promotor activity by cell based assay ChEMBL. 20045316
IC50 (binding) = 4.5 nM Inhibition of HDAC4 ChEMBL. 20045316
IC50 (binding) = 11 nM Inhibition of HDAC1 ChEMBL. 20045316
IC50 (binding) = 280 nM Inhibition of HDAC6 ChEMBL. 20045316

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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