Detailed information for compound 1213540

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 537.692 | Formula: C27H47N5O6
  • H donors: 5 H acceptors: 6 LogP: 3.23 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCC[C@H]1NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@@H]2N(C(=O)[C@@H](NC1=O)CCCCC)CCC2
  • InChi: 1S/C27H47N5O6/c1-3-5-8-13-19-25(35)30-21(15-9-6-4-2)27(37)32-18-12-16-22(32)26(36)29-20(24(34)28-19)14-10-7-11-17-23(33)31-38/h19-22,38H,3-18H2,1-2H3,(H,28,34)(H,29,36)(H,30,35)(H,31,33)/t19-,20+,21+,22-/m1/s1
  • InChiKey: IYOLVIFIJXUYFW-CLAROIROSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histone deacetylase 6 Starlite/ChEMBL References
Mus musculus histone deacetylase 6 Starlite/ChEMBL References
Homo sapiens histone deacetylase 4 Starlite/ChEMBL References
Homo sapiens histone deacetylase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K01463 Hdac3 [EC:3.5.1.-], putative Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi histone deacetylase 1 (HD1) Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum histone deacetylase HDA2/Rpd3p Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium falciparum histone deacetylase 2 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium parvum histone deactylase of possible bacterial origin with ankyrin repeats at the N-terminus Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi Histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi histone deacetylase 3 (HD3) Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC1 Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei gambiense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Entamoeba histolytica histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase 1,histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium vivax histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium falciparum histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum ko:K06067 histone deacetylase 1/2, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Giardia lamblia Histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase hda2 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei histone deacetylase 3 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase 7A Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum RPD3/HD1 histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium knowlesi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC2 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii Histone deacetylase family, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium berghei histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum IPR000286,Histone deacetylase superfamily;IPR013838,Beta tubulin, autoregulation binding site,domain-containing Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC3 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cruzipain precursor, putative 0.0132 0.0212 0.116
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0039 0.0029 0.0032
Leishmania major hypothetical protein, conserved 0.007 0.0091 0.0496
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0003 0.0007
Echinococcus multilocularis synaptojanin 1 0.0024 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Onchocerca volvulus Bile acid receptor homolog 0.0081 0.0111 0.0928
Echinococcus granulosus intermediate filament protein 0.0174 0.0295 0.0322
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0022 0.0029
Echinococcus multilocularis heat shock protein 90 0.0065 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Echinococcus granulosus lysosomal alpha glucosidase 0.0361 0.0659 0.0721
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0038 0.0052
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0273 0.0488 0.1447
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0044 0.0048
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0046 0.0043 0.022
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0955 0.1823 1
Echinococcus granulosus hypothetical protein 0.0766 0.1453 0.1587
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0003 0.0014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0018 0.0093
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0234 0.0412 0.0451
Trichomonas vaginalis receptor histidine kinase, putative 0.004 0.0031 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.0111 0.0152
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Loa Loa (eye worm) cytochrome P450 0.0046 0.0043 0.0059
Echinococcus multilocularis cysteine protease 0.0035 0.0022 0.0022
Leishmania major mitochondrial DNA topoisomerase II 0.072 0.1362 0.747
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.003 0.0178
Loa Loa (eye worm) hypothetical protein 0.08 0.152 0.2074
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0081 0.0111 0.0122
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0089 0.0129 0.0141
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0038 0.0038
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0064 0.008 0.0433
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0044 0.0039 0.02
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0115 0.0179 0.0244
Loa Loa (eye worm) hypothetical protein 0.0394 0.0724 0.0988
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0086 0.0094
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0044 0.0039 0.0239
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Schistosoma mansoni thyroid hormone receptor 0.0081 0.0111 0.0122
Brugia malayi nuclear receptor NHR-88 0.0081 0.0111 0.0152
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.004 0.0031 0.0031
Echinococcus multilocularis histone deacetylase 8 0.0242 0.0427 0.0427
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi Thioredoxin reductase 0.0046 0.0044 0.006
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0083 0.0091
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0044 0.0039 0.0239
Onchocerca volvulus 0.0035 0.0022 0.0179
Echinococcus granulosus lamin 0.0174 0.0295 0.0322
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0028 0.0031
Trypanosoma brucei DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Trypanosoma cruzi DNA topoisomerase II, putative 0.0608 0.1143 0.6267
Onchocerca volvulus 0.0149 0.0246 0.205
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.004 0.0031 0.009
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0046 0.0043 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Giardia lamblia Sgs1 DNA helicase, putative 0.0042 0.0037 0.0096
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0086 0.0086
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0009 0.0012
Brugia malayi heat shock protein 90 0.0065 0.0081 0.011
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0079 0.0109 0.0149
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0079 0.0109 0.0909
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0149 0.0246 0.0657
Brugia malayi nuclear receptor NHR-88 0.0038 0.0028 0.0038
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0034 0.002 0.0107
Leishmania major cytochrome p450-like protein 0.0046 0.0043 0.0231
Brugia malayi Cytochrome P450 family protein 0.0064 0.0079 0.0108
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Echinococcus multilocularis histone deacetylase 1 0.0297 0.0535 0.0535
Schistosoma mansoni cpg binding protein 0.0386 0.0709 0.0774
Loa Loa (eye worm) hypothetical protein 0.0061 0.0073 0.0099
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.004 0.0031 0.0154
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0157 0.0856
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0363 0.0665 0.0907
Brugia malayi Pre-SET motif family protein 0.0233 0.0409 0.0559
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0079
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Schistosoma mansoni hypothetical protein 0.007 0.0092 0.01
Brugia malayi Metabotropic glutamate receptor precursor. 0.0079 0.0109 0.0149
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.009 0.0122
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0079 0.0109 0.029
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0145 0.0158
Trypanosoma brucei histone deacetylase 3 0.0344 0.0627 0.3436
Loa Loa (eye worm) hypothetical protein 0.0257 0.0457 0.0623
Plasmodium vivax glutathione reductase, putative 0.0046 0.0044 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Loa Loa (eye worm) histone deacetylase 0.0344 0.0627 0.0855
Loa Loa (eye worm) TOPoisomerase family member 0.0642 0.121 0.1651
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0048 0.0256
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0317 0.0573 0.1699
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0086 0.0086
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.01 0.011
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Trichomonas vaginalis DNA polymerase eta, putative 0.0148 0.0243 0.0648
Schistosoma mansoni SET domain protein 0.0044 0.0039 0.0043
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0116 0.018 0.048
Brugia malayi Steroid receptor seven-up type 2 0.0081 0.0111 0.0152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0394 0.0724 0.6033
Schistosoma mansoni metabotropic glutamate receptor 0.0079 0.0109 0.0119
Loa Loa (eye worm) hypothetical protein 0.0276 0.0495 0.0675
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0074 0.0099 0.0263
Echinococcus granulosus glutamate receptor subunit protein glur 0.0155 0.0257 0.0281
Brugia malayi Doublecortin family protein 0.0066 0.0083 0.0114
Loa Loa (eye worm) hypothetical protein 0.0363 0.0665 0.0907
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0082 0.0112
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0642 0.121 0.1651
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Echinococcus multilocularis neuropeptide receptor A26 0.0978 0.1868 0.1868
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0044 0.0039 0.02
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Brugia malayi hypothetical protein 0.0079 0.0109 0.0149
Leishmania major cytochrome p450-like protein 0.0103 0.0155 0.0849
Schistosoma mansoni zinc finger protein 0.0043 0.0038 0.0042
Onchocerca volvulus 0.0079 0.0109 0.0909
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Echinococcus granulosus histone deacetylase 6 0.0359 0.0656 0.0717
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Schistosoma mansoni survival motor neuron protein 0.0407 0.075 0.0819
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0044 0.0039 0.0115
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0075 0.01 0.0137
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0137 0.0221 0.1363
Treponema pallidum exodeoxyribonuclease (exoA) 0.0119 0.0188 0.05
Onchocerca volvulus 0.0052 0.0056 0.0464
Schistosoma mansoni bromodomain containing protein 0.0094 0.0137 0.0149
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0772 0.1465 0.16
Echinococcus multilocularis musashi 0.0174 0.0295 0.0295
Plasmodium falciparum DNA repair protein REV1, putative 0.0037 0.0026 0.0159
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0377 0.0692 0.205
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Echinococcus multilocularis lysosomal alpha glucosidase 0.0361 0.0659 0.0659
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0182 0.0995
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0056 0.0063 0.0166
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0276 0.0495 0.0541
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0044 0.0039 0.0115
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Loa Loa (eye worm) hypothetical protein 0.0074 0.0099 0.0135
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0159 0.0265 0.1455
Echinococcus granulosus dnaJ subfamily C 6 0.007 0.0092 0.01
Brugia malayi Cell division protein ftsZ 0.0156 0.0259 0.0354
Trypanosoma brucei glucosidase, putative 0.008 0.011 0.06
Schistosoma mansoni bromodomain containing protein 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0046
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0079 0.0109 0.0109
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0032 0.0032
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0273 0.0488 0.0666
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Chlamydia trachomatis DNA gyrase subunit A 0.0137 0.0221 0.2555
Mycobacterium ulcerans two component sensor kinase MprB 0.004 0.0031 0.0154
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0083 0.0083
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0188 0.1155
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.003 0.0178
Leishmania major C-8 sterol isomerase-like protein 0.0396 0.0729 0.3994
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0009 0.0009
Leishmania major extracellular receptor, putative 0.0079 0.0109 0.0594
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0145 0.0386
Schistosoma mansoni transcription factor LCR-F1 0.0148 0.0244 0.0266
Loa Loa (eye worm) hypothetical protein 0.1994 0.3857 0.5263
Schistosoma mansoni zinc finger protein 0.0038 0.0028 0.0031
Mycobacterium ulcerans cell division protein FtsZ 0.0326 0.0591 0.3267
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0046 0.0043 0.022
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Plasmodium falciparum histone deacetylase, putative 0.0344 0.0627 0.3875
Echinococcus granulosus dna polymerase eta 0.0147 0.0241 0.0263
Echinococcus granulosus sodium channel protein 0.0036 0.0025 0.0027
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0944 0.1802 0.5345
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0012 0.003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Plasmodium vivax DNA gyrase subunit A, putative 0.0137 0.0221 0.1363
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0008 0.0012
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0082 0.009
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Echinococcus multilocularis protein dispatched 1 0.0049 0.005 0.005
Echinococcus multilocularis sentrin specific protease 8 0.0071 0.0093 0.0093
Echinococcus multilocularis neuroligin 0.0637 0.12 0.12
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0028 0.0028
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0046 0.0043 0.022
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0046 0.0043 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0081 0.0111 0.0152
Leishmania major cytochrome p450-like protein 0.0046 0.0043 0.0231
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0046 0.0043 0.022
Echinococcus multilocularis histone deacetylase 6 0.0359 0.0656 0.0656
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.085 0.1617 0.8867
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0452 0.0838 0.4596
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0048 0.0052
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0081 0.0111 0.0111
Schistosoma mansoni RAR-like nuclear receptor 0.0081 0.0111 0.0122
Schistosoma mansoni histone deacetylase hda2 0.0359 0.0656 0.0717
Chlamydia trachomatis glutamine binding protein 0.0397 0.0731 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0944 0.1802 1
Toxoplasma gondii DNA topoisomerase 2, putative 0.0642 0.121 0.7482
Schistosoma mansoni synaptojanin 0.0024 0.0001 0.0001
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1174 0.2251 0.6024
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Schistosoma mansoni polycystin 1-related 0.0066 0.0083 0.0091
Trypanosoma brucei DNA topoisomerase ii 0.072 0.1362 0.747
Schistosoma mansoni cytochrome P450 0.0046 0.0043 0.0047
Schistosoma mansoni tsg101-related 0.0183 0.0312 0.0341
Leishmania major DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.004 0.0105
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0052 0.0055 0.006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.3769 0.733 0.8009
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0159 0.0265 0.3803
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0028 0.0028
Echinococcus multilocularis histone deacetylase 3 0.0297 0.0535 0.0535
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0028 0.0009 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0044 0.0044
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0024 0.0001 0.0001
Echinococcus multilocularis conserved hypothetical protein 0.0742 0.1406 0.1406
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0066 0.0083 0.0113
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0119 0.0188 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0026 0.0066
Giardia lamblia DNA damage repair protein 0.0037 0.0026 0.0069
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0048 0.0065
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0034 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0102 0.0153 0.0209
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Leishmania major DNA polymerase kappa, putative 0.0037 0.0026 0.0141
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0035 0.0023 0.012
Echinococcus granulosus dna polymerase kappa 0.0148 0.0243 0.0266
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trypanosoma brucei protein kinase, putative 0.006 0.0071 0.0385
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Brugia malayi hypothetical protein 0.0132 0.0213 0.029
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0044 0.0039 0.0054
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0151 0.0165
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0637 0.12 0.12
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi nuclear receptor NHR-67 0.0038 0.0028 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0042 0.0037 0.0037
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Echinococcus multilocularis GPCR, family 2 0.0115 0.0179 0.0179
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Brugia malayi hypoxia-induced factor 1 0.0338 0.0615 0.0839
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.0522 0.057
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0048 0.0125
Mycobacterium leprae Probable lipase LipE 0.0273 0.0488 0.2697
Brugia malayi exodeoxyribonuclease III family protein 0.0119 0.0188 0.0256
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Schistosoma mansoni heat shock protein 0.0065 0.0081 0.0088
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0149 0.0246 0.1349
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.0037 0.004
Trypanosoma cruzi pantothenate kinase subunit, putative 0.003 0.0013 0.0065
Schistosoma mansoni DNA helicase recq5 0.0042 0.0037 0.004
Trichomonas vaginalis adenylate cyclase, putative 0.0028 0.0009 0.0022
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Toxoplasma gondii thioredoxin reductase 0.0046 0.0044 0.0266
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0046 0.0043 0.0125
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0046 0.0043 0.0125
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0155 0.0257 0.0257
Schistosoma mansoni histone deacetylase 0.0297 0.0535 0.0584
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0044 0.0039 0.0103
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0137 0.0221 0.0589
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Mycobacterium ulcerans DNA polymerase IV 0.0148 0.0243 0.1333
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0034 0.0037
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0452 0.0838 0.4596
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Onchocerca volvulus 0.0305 0.0551 0.4594
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0159 0.0265 0.1635
Brugia malayi cytoplasmic intermediate filament protein 0.0093 0.0136 0.0186
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0034 0.002 0.0121
Loa Loa (eye worm) inositol-1 0.0159 0.0265 0.0362
Echinococcus granulosus nmda type glutamate receptor 0.1954 0.3779 0.4129
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0028 0.0028
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Loa Loa (eye worm) fibroinase 0.0035 0.0022 0.0029
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0046 0.0043 0.0231
Leishmania major protein kinase, putative 0.003 0.0013 0.0065
Loa Loa (eye worm) carboxylesterase 0.0637 0.12 0.1637
Leishmania major histone deacetylase, putative 0.0344 0.0627 0.3436
Loa Loa (eye worm) acetylcholinesterase 1 0.3769 0.733 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0141 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.0488 0.2675
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0044 0.0039 0.0054
Plasmodium vivax endoplasmin, putative 0.0065 0.0081 0.0496
Onchocerca volvulus 0.0024 0.0001 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0273 0.0488 0.2675
Brugia malayi hypothetical protein 0.0081 0.0112 0.0153
Chlamydia trachomatis DNA gyrase subunit B 0.0299 0.0539 0.7202
Mycobacterium tuberculosis Carboxylesterase LipT 0.0637 0.12 0.3559
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0075 0.01 0.01
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0048 0.0125
Brugia malayi ImpB/MucB/SamB family protein 0.012 0.0188 0.0257
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Echinococcus granulosus glutamate NMDA receptor subunit 0.0155 0.0257 0.0281
Toxoplasma gondii peptidylprolyl isomerase 0.0064 0.008 0.0488
Schistosoma mansoni myst-related protein 0.0045 0.0042 0.0046
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0022 0.0179
Mycobacterium ulcerans epoxide hydrolase EphA 0.0317 0.0573 0.3169
Echinococcus multilocularis neuropeptide s receptor 0.0978 0.1868 0.1868
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0119 0.0188 0.1024
Onchocerca volvulus 0.0044 0.0039 0.0329
Loa Loa (eye worm) hypothetical protein 0.0132 0.0213 0.029
Brugia malayi hypothetical protein 0.0043 0.0037 0.005
Giardia lamblia Kinase, PLK 0.0103 0.0155 0.0414
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Schistosoma mansoni ATP-binding cassette transporter 0.0155 0.0257 0.0281
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0119 0.0188 0.1024
Schistosoma mansoni lipoxygenase 0.0185 0.0317 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0048 0.0256
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0092 0.0135 0.0147
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0044 0.0039 0.0115
Schistosoma mansoni steroid hormone receptor ad4bp 0.0081 0.0111 0.0122
Trypanosoma cruzi cytochrome P450, putative 0.0103 0.0155 0.0849
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0092 0.0135 0.0135
Echinococcus multilocularis tumor protein p63 0.0661 0.1248 0.1248
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0039 0.0103
Plasmodium vivax multidomain scavenger receptor, putative 0.0066 0.0083 0.051
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Echinococcus multilocularis histone deacetylase 0.0344 0.0627 0.0627
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0022 0.0055
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0044 0.0266
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0028 0.0038
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.0093 0.0127
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.0317 0.0346
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Echinococcus granulosus traf and tnf receptor associated protein 0.0024 0.0001 0.0001
Brugia malayi hypothetical protein 0.0043 0.0037 0.005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1933 0.3737 1
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0159 0.0471
Loa Loa (eye worm) glutamate receptor 2 0.0155 0.0257 0.035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0028 0.0234
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Echinococcus granulosus transcription factor Dp 1 0.004 0.0032 0.0035
Trypanosoma brucei DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Mycobacterium leprae Possible regulatory protein 0.0028 0.0009 0.0032
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.0012 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.004 0.0031 0.009
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0048 0.0052
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0436 0.0807 0.6723
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0003 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.011 0.06
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0081 0.0111 0.0152
Trypanosoma brucei telomerase reverse transcriptase 0.0092 0.0134 0.073
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0064 0.008 0.0433
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0035 0.0038
Brugia malayi Calcitonin receptor-like protein seb-1 0.0363 0.0665 0.0907
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0044 0.0039 0.02
Echinococcus multilocularis geminin 0.1605 0.3095 0.3095
Onchocerca volvulus 0.0637 0.12 1
Toxoplasma gondii ABC1 family protein 0.0273 0.0488 0.3017
Echinococcus granulosus flap endonuclease 1 0.0028 0.0008 0.0009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Echinococcus granulosus histone deacetylase 8 0.0242 0.0427 0.0467
Brugia malayi hypothetical protein 0.0637 0.12 0.1637
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0174 0.0295 0.0402
Echinococcus granulosus DNA topoisomerase 1 0.085 0.1617 0.1767
Schistosoma mansoni lamin 0.0174 0.0295 0.0322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni cpg binding protein 0.0363 0.0664 0.0725
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.0037 0.004
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0048 0.0125
Schistosoma mansoni alpha glucosidase 0.008 0.011 0.012
Brugia malayi CXXC zinc finger family protein 0.0363 0.0664 0.0906
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0037 0.0096
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0148 0.0243 0.0648
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.009 0.0122
Echinococcus granulosus metabotropic glutamate receptor 2 0.0079 0.0109 0.0119
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0037 0.0096
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0023 0.0031
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Brugia malayi beta-NAC-like protein 0.0039 0.003 0.004
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Plasmodium vivax vivapain-2 0.0035 0.0022 0.0128
Schistosoma mansoni alpha-glucosidase 0.031 0.0561 0.0613
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0026 0.0141
Echinococcus multilocularis neutral sphingomyelinase 0.0024 0.0001 0.0001
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0642 0.121 0.121
Onchocerca volvulus 0.0035 0.0022 0.0179
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0041 0.0034 0.0207
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0028 0.0038
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.022 0.0384 0.0384
Brugia malayi Guanylyl cyclase protein 23 0.0079 0.0109 0.0149
Trichomonas vaginalis esterase, putative 0.0273 0.0488 0.1305
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0148 0.0244 0.0266
Schistosoma mansoni nuclear receptor 0.0038 0.0028 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0081 0.0111 0.0152
Echinococcus multilocularis deoxyribonuclease 1 2 0.0024 0.0001 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0115 0.0179 0.0195
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0028 0.0031
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0044 0.0039 0.0039
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0066 0.0083 0.0113
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.022 0.0384 0.0524
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0008 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.0522 0.057
Plasmodium falciparum flap endonuclease 1 0.0028 0.0008 0.0047
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.004 0.0031 0.009
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0012 0.0061
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0159 0.0471
Loa Loa (eye worm) hypothetical protein 0.0202 0.035 0.0477
Leishmania major pantothenate kinase subunit, putative 0.003 0.0013 0.0065
Trypanosoma brucei histone deacetylase 2 0.0242 0.0427 0.234
Brugia malayi intermediate filament protein 0.0174 0.0295 0.0402
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0081 0.0111 0.0111
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0361 0.0659 0.09
Brugia malayi Cytochrome P450 family protein 0.0103 0.0155 0.0212
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0034 0.0021 0.0023
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0142 0.0232 0.1274
Echinococcus multilocularis 0.0046 0.0043 0.0043
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0009 0.0022
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.072 0.1362 0.747
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0081 0.0111 0.0152
Trichomonas vaginalis rotamase, putative 0.0064 0.008 0.0211
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0081 0.044
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) histone deacetylase 11 0.0242 0.0427 0.0583
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0116 0.018 0.018
Brugia malayi Bromodomain containing protein 0.0044 0.004 0.0054
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0081 0.0111 0.0928
Giardia lamblia Telomerase catalytic subunit 0.0092 0.0134 0.0356
Trypanosoma cruzi ISWI complex protein 0.0038 0.0028 0.015
Trypanosoma brucei Heat shock protein 83, putative 0.0065 0.0081 0.044
Echinococcus granulosus glutamate receptor 2 0.0079 0.0109 0.0119
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Schistosoma mansoni protein kinase 0.0079 0.0109 0.0119
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.007 0.009 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0046 0.0043 0.0125
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.003 0.0158
Echinococcus granulosus BC026374 protein S09 family 0.0637 0.12 0.1311
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0092 0.0135 0.0147
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0103 0.0155 0.0846
Brugia malayi hypothetical protein 0.0052 0.0056 0.0077
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0151 0.0206
Echinococcus multilocularis muscleblind protein 1 0.08 0.152 0.152
Loa Loa (eye worm) hypothetical protein 0.3769 0.733 1
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0046 0.0043 0.022
Loa Loa (eye worm) hypothetical protein 0.0396 0.0729 0.0994
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0086 0.0094
Echinococcus multilocularis traf and tnf receptor associated protein 0.0024 0.0001 0.0001
Onchocerca volvulus Histone deacetylase 10 homolog 0.0242 0.0427 0.3561
Schistosoma mansoni rab6-interacting 0.0066 0.0083 0.0091
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Leishmania major developmentally regulated phosphoprotein-like protein 0.004 0.0031 0.0166
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0119 0.0188 0.1024
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0064 0.0079 0.0483
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0046 0.0043 0.022
Schistosoma mansoni endoplasmin 0.0065 0.0081 0.0088
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Trypanosoma cruzi DNA topoisomerase II, putative 0.0608 0.1143 0.6267
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0039 0.0054
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0048 0.0256
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1933 0.3737 1
Echinococcus multilocularis protein patched 0.0043 0.0038 0.0038
Plasmodium vivax histone deacetylase 2, putative 0.0344 0.0627 0.3875
Echinococcus granulosus neutral alpha glucosidase AB 0.008 0.011 0.012
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.008 0.011 0.0293
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0016
Loa Loa (eye worm) beta-lactamase 0.0273 0.0488 0.0666
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.4699 0.9152 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0081 0.0111 0.0928
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0022 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0081 0.0111 0.0152
Giardia lamblia Heat shock protein HSP 90-alpha 0.0065 0.0081 0.0214
Brugia malayi Histone deacetylase family protein 0.0344 0.0627 0.0855
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0112 0.0173 0.0462
Schistosoma mansoni hypothetical protein 0.0036 0.0025 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0081 0.0111 0.0122
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0081 0.0111 0.0152
Leishmania major trypanothione reductase 0.0046 0.0044 0.0236
Plasmodium falciparum DNA topoisomerase 3, putative 0.0034 0.0021 0.0123
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0188 0.05
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0037 0.0096
Mycobacterium leprae cell division protein FtsZ 0.0326 0.0591 0.3267
Echinococcus multilocularis zinc finger protein 0.0043 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0046 0.0043 0.0125
Brugia malayi hypothetical protein 0.022 0.0384 0.0524
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0037 0.0221
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0018 0.0093
Leishmania major histone deacetylase, putative 0.0297 0.0535 0.293
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0155 0.0848
Onchocerca volvulus 0.0637 0.12 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0028 0.0031
Brugia malayi Cytochrome P450 family protein 0.0046 0.0043 0.0059
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.043 0.0795 0.1085
Brugia malayi Probable DNA topoisomerase II 0.0642 0.121 0.1651
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Brugia malayi GRF zinc finger family protein 0.0034 0.0021 0.0028
Plasmodium vivax histone deacetylase, putative 0.0344 0.0627 0.3875
Loa Loa (eye worm) hypothetical protein 0.0044 0.0039 0.0054
Echinococcus granulosus atrial natriuretic peptide receptor 0.0079 0.0109 0.0119
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Echinococcus multilocularis para nitrobenzyl esterase 0.0637 0.12 0.12
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0112 0.0172 0.0938
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0028 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Echinococcus granulosus lamin dm0 0.0174 0.0295 0.0322
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Brugia malayi histone deacetylase 1 (HD1) 0.0297 0.0535 0.073
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0022 0.0128
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0034 0.002 0.002
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Loa Loa (eye worm) carboxylesterase 0.3769 0.733 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0024 0.0001 0.0001
Brugia malayi TAR-binding protein 0.0135 0.0217 0.0296
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0092 0.0135 0.0135
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0052 0.0055 0.0336
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Schistosoma mansoni DNA topoisomerase type I 0.085 0.1617 0.1767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium leprae Conserved hypothetical protein 0.0046 0.0043 0.022
Mycobacterium tuberculosis Probable lipase LipD 0.0273 0.0488 0.1447
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Echinococcus granulosus metabotropic glutamate receptor 5 0.0079 0.0109 0.0119
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Brugia malayi Protein kinase domain containing protein 0.0098 0.0145 0.0198
Schistosoma mansoni cell polarity protein 0.0142 0.0232 0.0253
Onchocerca volvulus 0.0273 0.0488 0.407
Plasmodium vivax histone deacetylase 1, putative 0.0297 0.0535 0.3304
Schistosoma mansoni single-minded 0.0109 0.0167 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0048 0.0125
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.009 0.0487
Trypanosoma cruzi histone deacetylase 1, putative 0.0297 0.0535 0.293
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0081 0.0111 0.0152
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Loa Loa (eye worm) DNA topoisomerase I 0.085 0.1617 0.2206
Echinococcus granulosus nmda type glutamate receptor 0.1482 0.2854 0.3118
Entamoeba histolytica DNA topoisomerase II, putative 0.0642 0.121 0.3236
Loa Loa (eye worm) hypothetical protein 0.0115 0.0179 0.0244
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0012 0.003
Loa Loa (eye worm) ctsf protein 0.0035 0.0022 0.0029
Loa Loa (eye worm) doublecortin family protein 0.0066 0.0083 0.0114
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.085 0.1617 0.8867
Mycobacterium tuberculosis Probable reductase 0.0105 0.0159 0.0471
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0038 0.0042
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0437
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Brugia malayi DNA topoisomerase I 0.085 0.1617 0.2206
Loa Loa (eye worm) hypothetical protein 0.0065 0.0081 0.0111
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0012 0.0061
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.004 0.0031 0.0403
Mycobacterium ulcerans hypothetical protein 0.0149 0.0246 0.1349
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.004 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.08 0.152 0.2074
Schistosoma mansoni glutaminase 0.0291 0.0524 0.0572
Loa Loa (eye worm) hypothetical protein 0.0265 0.0472 0.0644
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Schistosoma mansoni carbon catabolite repressor protein 0.0024 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Mycobacterium ulcerans DNA gyrase subunit A 0.0137 0.0221 0.121
Echinococcus granulosus inositol monophosphatase 1 0.0159 0.0265 0.029
Giardia lamblia Pms1-like protein 0.004 0.0031 0.0081
Leishmania major basic transcription factor 3a, putative 0.0039 0.003 0.0158
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.012 0.0188 0.0206
Plasmodium falciparum DNA gyrase subunit A 0.0137 0.0221 0.1363
Schistosoma mansoni intermediate filament proteins 0.0174 0.0295 0.0322
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0119 0.0188 0.1024
Giardia lamblia Fructose-bisphosphate aldolase 0.1933 0.3737 1
Leishmania major protein kinase, putative 0.0039 0.0029 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0116 0.018 0.0246
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0084 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0029
Trichomonas vaginalis penicillin-binding protein, putative 0.0273 0.0488 0.1305
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.0045 0.0045
Echinococcus granulosus ecdysone induced protein 78C 0.0081 0.0111 0.0122
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0034 0.0021 0.0123
Schistosoma mansoni histone deacetylase 4 5 0.0344 0.0627 0.0685
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0073 0.0073
Echinococcus multilocularis histone deacetylase 7 0.0344 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Echinococcus granulosus receptor type guanylyl cyclase 0.0079 0.0109 0.0119
Entamoeba histolytica DNA topoisomerase III, putative 0.0034 0.0021 0.0053
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0436 0.0807 0.6723
Brugia malayi Carboxylesterase family protein 0.3769 0.733 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.0317 0.0317
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0022 0.0179
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0119 0.0188 0.0256
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.003 0.0158
Echinococcus granulosus cathepsin l1 0.0035 0.0022 0.0023
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0046 0.0043 0.022
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0048 0.0052
Onchocerca volvulus 0.0024 0.0001 0.0007
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.003 0.0012 0.01
Loa Loa (eye worm) GTP-binding protein 0.0142 0.0232 0.0316
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0071 0.0071
Mycobacterium tuberculosis Conserved hypothetical protein 0.0503 0.0938 0.2783
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0003 0.0014
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0047 0.0046 0.005
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Brugia malayi glutaminase DH11.1 0.0291 0.0524 0.0715
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Toxoplasma gondii propionate-CoA ligase 0.0044 0.0039 0.0239
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0246 0.1349
Echinococcus multilocularis neutral alpha glucosidase AB 0.008 0.011 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0081 0.0111 0.0122
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0149 0.0246 0.0727
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.004 0.0031 0.0081
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0025 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Brugia malayi cell division control protein 2 homolog 0.0048 0.0048 0.0065
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.003 0.0158
Echinococcus multilocularis histone deacetylase 6 0.0344 0.0627 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0028 0.0073
Onchocerca volvulus 0.0035 0.0022 0.0179
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0008 0.002
Onchocerca volvulus 0.0034 0.0021 0.0173
Schistosoma mansoni hypothetical protein 0.0148 0.0244 0.0266
Loa Loa (eye worm) hypothetical protein 0.0046 0.0044 0.006
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0155 0.0257 0.0281
Brugia malayi GTP-binding protein 0.0142 0.0232 0.0316
Onchocerca volvulus 0.0081 0.0111 0.0928
Echinococcus multilocularis Polycystic kidney disease protein 0.0066 0.0083 0.0083
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0044 0.0039 0.0239
Toxoplasma gondii NAC domain-containing protein 0.0039 0.003 0.0178
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Onchocerca volvulus 0.0081 0.0112 0.0931
Leishmania major hypothetical protein, conserved 0.004 0.0031 0.0166
Toxoplasma gondii ThiF family protein 0.0034 0.002 0.0121
Onchocerca volvulus 0.0407 0.075 0.6249
Trypanosoma brucei histone deacetylase 1 0.0297 0.0535 0.293
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Mycobacterium ulcerans glutaminase 0.0291 0.0524 0.2893
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0086 0.0526
Plasmodium falciparum glutathione reductase 0.0046 0.0044 0.0266
Loa Loa (eye worm) hypothetical protein 0.0248 0.044 0.06
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0112 0.069
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0036 0.0025 0.0027
Echinococcus granulosus transcription factor btf3 0.0039 0.003 0.0032
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0396 0.0729 0.3994
Brugia malayi histone deacetylase 11 0.0242 0.0427 0.0583
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0081 0.0111 0.0152
Trypanosoma cruzi hypothetical protein 0.0071 0.0093 0.0508
Loa Loa (eye worm) histone deacetylase 7A 0.0344 0.0627 0.0855
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0116 0.018 0.048
Trichomonas vaginalis spcc417.12 protein, putative 0.0637 0.12 0.321
Mycobacterium ulcerans hypothetical protein 0.0503 0.0938 0.5199
Schistosoma mansoni DNA polymerase IV / kappa 0.0037 0.0026 0.0029
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Loa Loa (eye worm) hypothetical protein 0.0097 0.0143 0.0195
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0143 0.0156
Plasmodium falciparum DNA gyrase subunit B 0.0377 0.0692 0.4274
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Leishmania major DNA polymerase eta, putative 0.0147 0.0241 0.1317
Echinococcus granulosus glutamate receptor NMDA 0.1402 0.2698 0.2948
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0044 0.0039 0.0043
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0642 0.121 0.1651
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0273 0.0488 0.0534
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0407 0.075 0.1023
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.004 0.0031 0.0034
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Loa Loa (eye worm) glutamate receptor 0.0079 0.0109 0.0149
Giardia lamblia DNA topoisomerase III 0.0034 0.0021 0.0053
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Brugia malayi ecdysone receptor 0.0038 0.0028 0.0038
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0022 0.0023
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0001 0.0001
Trypanosoma brucei polo-like protein kinase 0.0103 0.0155 0.0848
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0046 0.0043 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0115 0.0179 0.0195
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0246 0.1349
Schistosoma mansoni patched 1 0.0043 0.0038 0.0042
Trichomonas vaginalis receptor histidine kinase, putative 0.004 0.0031 0.0081
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0034 0.0021 0.0021
Chlamydia trachomatis DNA gyrase subunit B 0.0377 0.0692 0.9425
Plasmodium falciparum LCCL domain-containing protein 0.0066 0.0083 0.051
Leishmania major DNA topoisomerase ii 0.0608 0.1143 0.6267
Schistosoma mansoni loxhd1 0.0066 0.0083 0.0091
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.019 0.1037
Echinococcus granulosus histone deacetylase 6 0.0344 0.0627 0.0685
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0116 0.018 0.048
Echinococcus multilocularis inositol monophosphatase 1 0.0159 0.0265 0.0265
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0119 0.0188 0.0554
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.0093 0.0248
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0003 0.0014
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0081 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Trypanosoma brucei glycosyl hydrolase-like protein 0.003 0.0012 0.0061
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0042 0.0037 0.0037
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0084 0.0118 0.0129
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0071 0.0093 0.0102
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Echinococcus multilocularis glutamate receptor 2 0.0234 0.0412 0.0412
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0028 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.029 0.0522 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0028 0.0073
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0071 0.0385
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0044 0.0039 0.02
Trypanosoma brucei Vps23 core domain containing protein, putative 0.007 0.0091 0.0496
Toxoplasma gondii hypothetical protein 0.0052 0.0055 0.0336
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Mycobacterium ulcerans hypothetical protein 0.0037 0.0026 0.0128
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0022 0.0023
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0028 0.0038
Echinococcus multilocularis dual specificity 0.0098 0.0145 0.0145
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0155 0.0212
Echinococcus multilocularis lamin 0.0174 0.0295 0.0295
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0112 0.0612
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0008 0.002
Onchocerca volvulus 0.0038 0.0028 0.0234
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0112 0.069
Echinococcus multilocularis dnaJ subfamily B 0.4699 0.9152 0.9152
Schistosoma mansoni pyruvate dehydrogenase 0.004 0.0031 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0082 0.0115 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0046 0.0043 0.0125
Loa Loa (eye worm) hypothetical protein 0.0366 0.067 0.0914
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0188 0.1155
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.0009 0.0009
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Leishmania major glycosyl hydrolase-like protein 0.003 0.0012 0.0061
Onchocerca volvulus 0.0079 0.0109 0.0909
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0024 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Trichomonas vaginalis hypothetical protein 0.0044 0.004 0.0105
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0137 0.0221 0.3163
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.004 0.0031 0.0188
Echinococcus multilocularis carboxylesterase 5A 0.3769 0.733 0.733
Schistosoma mansoni cell polarity protein 0.0142 0.0232 0.0253
Trypanosoma brucei trypanothione reductase 0.0046 0.0044 0.0236
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Loa Loa (eye worm) latrophilin receptor protein 2 0.0115 0.0179 0.0244
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0081 0.0111 0.0122
Brugia malayi nuclear hormone receptor 0.0081 0.0111 0.0152
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Entamoeba histolytica hypothetical protein 0.0039 0.003 0.0077
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.004 0.0031 0.0081
Trypanosoma brucei C-8 sterol isomerase, putative 0.0396 0.0729 0.3994
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0036 0.0025 0.0131
Trypanosoma brucei histone deacetylase, putative 0.0344 0.0627 0.3436
Trypanosoma cruzi DNA polymerase eta, putative 0.0147 0.0241 0.1317
Loa Loa (eye worm) STAT protein 0.0154 0.0255 0.0347
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Leishmania major alpha glucosidase II subunit, putative 0.008 0.011 0.06
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0012 0.003
Schistosoma mansoni myst-related protein 0.0045 0.0042 0.0046
Entamoeba histolytica protein kinase, putative 0.0098 0.0145 0.0386
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0041 0.0034 0.0034
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Echinococcus granulosus p2X purinoceptor 4 0.0133 0.0214 0.0234
Schistosoma mansoni thyroid hormone receptor 0.0081 0.0111 0.0122
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0034 0.002 0.0022
Plasmodium falciparum acyl-CoA synthetase 0.0112 0.0172 0.106
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Leishmania major DNA topoisomerase 1A 0.0034 0.0021 0.0109
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0246 0.1345
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0273 0.0488 0.1447
Treponema pallidum DNA topoisomerase I (topA) 0.0034 0.0021 0.0053
Mycobacterium ulcerans lipase LipD 0.0273 0.0488 0.2697
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0159 0.0265 0.0707
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.004 0.0031 0.009
Echinococcus multilocularis sodium channel protein 0.0036 0.0025 0.0025
Entamoeba histolytica hypothetical protein 0.0098 0.0145 0.0386
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.004 0.0105
Loa Loa (eye worm) hypothetical protein 0.0171 0.0289 0.0394
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0149 0.0246 0.0727
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0081 0.0111 0.0122
Brugia malayi MH2 domain containing protein 0.0253 0.0449 0.0612
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0642 0.121 0.1322
Brugia malayi RNA binding protein 0.0135 0.0217 0.0296
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0028 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0081 0.0441
Brugia malayi DNA topoisomerase III 0.0034 0.0021 0.0028
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0098 0.0145 0.0791
Brugia malayi nuclear receptor RXR 0.0043 0.0037 0.005
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0182 0.0539
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.011 0.06
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.004 0.0031 0.009
Echinococcus granulosus mixed lineage leukemia protein mll 0.0092 0.0135 0.0147
Brugia malayi ThiF family protein 0.0052 0.0055 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0022 0.0022
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0081 0.0111 0.0122
Echinococcus granulosus tyrosine kinase 0.0079 0.0109 0.0119
Plasmodium falciparum zinc finger protein, putative 0.0045 0.0042 0.0253
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0141
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0112 0.069
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0086 0.0252
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Schistosoma mansoni hypothetical protein 0.0155 0.0257 0.0281
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0449 0.0612
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0028 0.0234
Brugia malayi F/Y-rich N-terminus family protein 0.0115 0.0179 0.0245
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.004 0.0031 0.0154
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0273 0.0488 0.1447
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0009 0.001
Toxoplasma gondii histone deacetylase HDAC3 0.0297 0.0535 0.3304
Leishmania major histone deacetylase, putative 0.0297 0.0535 0.293
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0046 0.0043 0.022
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.004 0.0031 0.009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0081 0.0111 0.0111
Schistosoma mansoni aryl hydrocarbon receptor 0.0109 0.0167 0.0183
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0159 0.0265 0.0707
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Schistosoma mansoni neutral sphingomyelinase 0.0024 0.0001 0.0001
Brugia malayi hypothetical protein 0.0038 0.0028 0.0038
Leishmania major DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.004 0.0031 0.0188
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0022 0.0055
Schistosoma mansoni cript-related 0.0024 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0046 0.0043 0.0125
Onchocerca volvulus 0.0044 0.0039 0.0329
Schistosoma mansoni coup transcription factor 0.0081 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0131 0.0143
Loa Loa (eye worm) endoplasmin 0.0065 0.0081 0.011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0452 0.0838 0.4596
Giardia lamblia Grp94/Hsp90 0.0025 0.0003 0.0007
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0022 0.0179
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Plasmodium falciparum protein kinase 5 0.0048 0.0048 0.0289
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Echinococcus multilocularis rho GTPase activating protein 20 0.0034 0.0021 0.0021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0148 0.0244 0.0244
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0034 0.0037
Echinococcus granulosus heat shock protein 90 0.0065 0.0081 0.0088
Echinococcus multilocularis cysteine protease 0.0035 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0092 0.0134 0.0356
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.004 0.0031 0.0081
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0273 0.0488 0.2697
Schistosoma mansoni BC026374 protein (S09 family) 0.0637 0.12 0.1311
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0026 0.0141
Echinococcus granulosus geminin 0.1605 0.3095 0.3382
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0217 0.0217
Treponema pallidum cell division protein FtsZ 0.0326 0.0591 0.158
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0028 0.0038
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0159 0.0265 0.0707
Echinococcus granulosus tumor protein p63 0.0661 0.1248 0.1364
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.004 0.0031 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0138
Trichomonas vaginalis helicase, putative 0.0082 0.0115 0.0304
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Loa Loa (eye worm) hypothetical protein 0.0257 0.0457 0.0623
Brugia malayi steroid hormone receptor 0.0081 0.0111 0.0152
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0044 0.0236
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0034 0.002 0.0121
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0047
Trichomonas vaginalis maltase-glucoamylase, putative 0.008 0.011 0.0293
Schistosoma mansoni lamin 0.0174 0.0295 0.0322
Schistosoma mansoni hypothetical protein 0.0056 0.0063 0.0069
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0363 0.0665 0.0907
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Toxoplasma gondii histone deacetylase HDAC2 0.0297 0.0535 0.3304
Schistosoma mansoni metabotropic glutamate receptor 0.0079 0.0109 0.0119
Brugia malayi Cell division protein ftsZ 0.0161 0.0268 0.0366
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0246 0.0656
Trypanosoma cruzi histone deacetylase, putative 0.0242 0.0427 0.234
Schistosoma mansoni tsg101-related 0.0183 0.0312 0.0341
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0081 0.0111 0.0152
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Schistosoma mansoni DNA polymerase eta 0.0147 0.0241 0.0263
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0055
Loa Loa (eye worm) hypothetical protein 0.043 0.0795 0.1085
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0046 0.0043 0.0125
Loa Loa (eye worm) follicle stimulating hormone receptor 0.052 0.0972 0.1326
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0039 0.0029 0.0076
Mycobacterium ulcerans carboxylesterase, LipT 0.0637 0.12 0.6653
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0155 0.0257 0.0281
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0044 0.0039 0.0039
Schistosoma mansoni lipoxygenase 0.0066 0.0083 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.0009 0.001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0046 0.0043 0.0125
Onchocerca volvulus 0.0637 0.12 1
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0048 0.0256
Echinococcus granulosus endoplasmin 0.0025 0.0003 0.0004
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0155 0.0257 0.0257
Plasmodium falciparum endoplasmin, putative 0.0053 0.0057 0.0346
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0159 0.0868
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0044 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi hypothetical protein 0.0366 0.067 0.0914
Trypanosoma cruzi Heat shock protein 83, putative 0.0065 0.0081 0.044
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0608 0.1143 0.6267
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0046 0.0043 0.0125
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0155 0.0257 0.0257
Plasmodium vivax acetyl-CoA synthetase, putative 0.0044 0.0039 0.0239
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0083 0.0114
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0034 0.0021 0.0053
Echinococcus multilocularis FTZ F1 alpha 0.0081 0.0111 0.0111
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0046 0.0043 0.022
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trichomonas vaginalis sensor histidine kinase, putative 0.004 0.0031 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0081 0.0111 0.0152
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0038 0.0028 0.0079
Entamoeba histolytica recQ family helicase, putative 0.0042 0.0037 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0164 0.0274 0.1499
Loa Loa (eye worm) hypothetical protein 0.0147 0.0241 0.0329
Mycobacterium ulcerans DNA polymerase IV 0.0148 0.0243 0.1333
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0127 0.0202 0.1103
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0071 0.0078
Mycobacterium tuberculosis Conserved hypothetical protein 0.012 0.0188 0.0557
Echinococcus multilocularis endoplasmin 0.0025 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0034 0.0037
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0079 0.0429
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0071 0.0385
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0048 0.0065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Echinococcus multilocularis glutamate receptor 2 0.0155 0.0257 0.0257
Brugia malayi Pre-SET motif family protein 0.0041 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0096 0.0141 0.0193
Schistosoma mansoni hypothetical protein 0.0407 0.075 0.0819
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.008 0.0433
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.004 0.0031 0.0154
Brugia malayi DnaJ domain containing protein 0.007 0.0092 0.0125
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0022 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0081 0.0214
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Schistosoma mansoni heat shock protein 0.0065 0.0081 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0082 0.0115 0.0304
Brugia malayi Glutamate receptor 2 precursor 0.0155 0.0257 0.035
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0131 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0079 0.0109 0.029
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0397 0.0731 0.1954
Trichomonas vaginalis hypothetical protein 0.0107 0.0163 0.0434
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0046 0.0043 0.0231
Trichomonas vaginalis set domain proteins, putative 0.0264 0.047 0.1256
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0046 0.0043 0.0125
Loa Loa (eye worm) hypothetical protein 0.0087 0.0125 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0155 0.0257 0.0281
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.007 0.0091 0.0496
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0009 0.0022
Schistosoma mansoni SET domain protein 0.0043 0.0038 0.0042
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0048 0.0052
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0243 0.1329
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0081 0.0111 0.0122
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0086 0.0466
Schistosoma mansoni hypothetical protein 0.1605 0.3095 0.3382
Schistosoma mansoni acetylcholinesterase 0.0637 0.12 0.1311
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0081 0.044
Treponema pallidum heat shock protein 90 0.0025 0.0003 0.0007
Echinococcus granulosus heat shock protein 90 0.0025 0.0003 0.0004
Loa Loa (eye worm) glutamate receptor 1 0.0155 0.0257 0.035
Plasmodium vivax topoisomerase I, putative 0.085 0.1617 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.004 0.0031 0.0154
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0089 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0243 0.1329
Plasmodium vivax acyl-CoA synthetase, putative 0.0112 0.0172 0.106
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0955 0.1823 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0018 0.0105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.004 0.0031 0.0154
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0028 0.0031
Echinococcus multilocularis lamin dm0 0.0174 0.0295 0.0295
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0637 0.12 0.321
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Trichomonas vaginalis glutaminase, putative 0.0291 0.0524 0.14
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0046 0.0043 0.022
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0039 0.0029 0.0076
Echinococcus multilocularis muscleblind protein 0.08 0.152 0.152
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Loa Loa (eye worm) hypothetical protein 0.0265 0.0472 0.0644
Entamoeba histolytica hypothetical protein 0.0334 0.0607 0.1624
Onchocerca volvulus 0.0044 0.0039 0.0329
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0083 0.0083
Mycobacterium tuberculosis Possible two component sensor kinase 0.004 0.0031 0.009
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0034 0.0034
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0034 0.0021 0.0053
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0057 0.015
Brugia malayi Flap endonuclease-1 0.0028 0.0008 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0235 0.0235
Schistosoma mansoni hypothetical protein 0.1605 0.3095 0.3382
Onchocerca volvulus 0.0041 0.0034 0.0285
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0048 0.0125
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0071 0.0188
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Echinococcus granulosus muscleblind protein 0.08 0.152 0.1661
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0046 0.0043 0.022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.008 0.011 0.0293
Echinococcus multilocularis receptor type guanylyl cyclase 0.0079 0.0109 0.0109
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0112 0.0172 0.0508
Brugia malayi PHD-finger family protein 0.0049 0.005 0.0069
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0235 0.0257
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0155 0.0848
Plasmodium falciparum thioredoxin reductase 0.0046 0.0044 0.0266
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0038 0.0028 0.0038
Echinococcus multilocularis DNA topoisomerase 1 0.085 0.1617 0.1617
Loa Loa (eye worm) hypothetical protein 0.0047 0.0045 0.0062
Echinococcus granulosus histone deacetylase 7 0.0344 0.0627 0.0685
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0098 0.0145 0.0198
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.004 0.0031 0.0166
Echinococcus multilocularis acetylcholinesterase 0.3769 0.733 0.733
Brugia malayi isocitrate dehydrogenase 0.0033 0.0018 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Giardia lamblia DNA topoisomerase III 0.0034 0.0021 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0038 0.01
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Onchocerca volvulus 0.0637 0.12 1
Brugia malayi Cytochrome P450 family protein 0.0103 0.0155 0.0212
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0071 0.0434
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0141
Echinococcus multilocularis NMDA receptor 0.0155 0.0257 0.0257
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Plasmodium vivax hypothetical protein, conserved 0.0273 0.0488 0.3017
Loa Loa (eye worm) RNA binding protein 0.0135 0.0217 0.0296
Leishmania major mitochondrial DNA polymerase beta 0.0955 0.1823 1
Schistosoma mansoni DNA topoisomerase II 0.0642 0.121 0.1322
Schistosoma mansoni tyrosine kinase 0.0079 0.0109 0.0119
Leishmania major histone deacetylase, putative 0.0344 0.0627 0.3436
Leishmania major ubiquitin-activating enzyme-like protein 0.0034 0.002 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Brugia malayi CCR4 0.0024 0.0001 0.0001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0182 0.0539
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0042 0.0037 0.0221
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0155 0.0414
Brugia malayi hypothetical protein 0.0148 0.0244 0.0332
Plasmodium vivax telomerase reverse transcriptase, putative 0.057 0.107 0.6618
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.004 0.0031 0.0154
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0044 0.0039 0.02
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0022 0.0128
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0944 0.1802 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0046 0.0043 0.0125
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0027 0.0007 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0212 0.116
Echinococcus multilocularis expressed protein 0.0066 0.0083 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Trypanosoma cruzi histone deacetylase, putative 0.0242 0.0427 0.234
Echinococcus multilocularis dna polymerase kappa 0.0148 0.0243 0.0243
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0334 0.0607 0.1624
Echinococcus granulosus acetylcholinesterase 0.3769 0.733 0.8009
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0246 0.1349
Brugia malayi bHLH-PAS transcription factor 0.0081 0.0112 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0081 0.0111 0.0152
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0112 0.069
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0018 0.0105
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trichomonas vaginalis DNA topoisomerase II, putative 0.0642 0.121 0.3236
Echinococcus granulosus cytochrome P450 2K1 0.0046 0.0043 0.0047
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0039 0.0212
Mycobacterium tuberculosis Probable lipase LipE 0.0273 0.0488 0.1447
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0048 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Schistosoma mansoni histone deacetylase hda2 0.0242 0.0427 0.0467
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0046 0.0043 0.022
Loa Loa (eye worm) hypothetical protein 0.3769 0.733 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0081 0.0111 0.0152
Trypanosoma cruzi DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0093 0.0136 0.0186
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0637 0.12 0.3559
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0028 0.0031
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0149 0.0246 0.1349
Brugia malayi Histone deacetylase 1 0.0297 0.0535 0.073
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0022 0.0029
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.005
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Trypanosoma brucei histone deacetylase 4 0.0344 0.0627 0.3436
Plasmodium falciparum DNA topoisomerase 2 0.0642 0.121 0.7482
Echinococcus granulosus acetylcholinesterase 0.3769 0.733 0.8009
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0131 0.0143
Loa Loa (eye worm) glutathione reductase 0.0046 0.0044 0.006
Giardia lamblia DNA repair protein RAD52 0.1174 0.2251 0.6024
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0048 0.0048
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0028 0.0038
Onchocerca volvulus 0.0066 0.0083 0.0694
Brugia malayi Muscleblind-like protein 0.08 0.152 0.2074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Loa Loa (eye worm) hypothetical protein 0.0052 0.0055 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0081 0.0111 0.0152
Schistosoma mansoni rotamase 0.0066 0.0083 0.009
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0111 0.0172 0.0172
Schistosoma mansoni glutamate receptor NMDA 0.0155 0.0257 0.0281
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0234 0.0412 0.0412
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0115 0.0178 0.0194
Mycobacterium leprae Probable two component sensor kinase MprB 0.004 0.0031 0.0154
Entamoeba histolytica protein kinase, putative 0.0098 0.0145 0.0386
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0042 0.0037 0.005
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0081 0.0214
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.009 0.0487
Schistosoma mansoni histone deacetylase 4 5 0.0344 0.0627 0.0685
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0119 0.0188 0.05
Trypanosoma brucei hypothetical protein, conserved 0.0273 0.0488 0.2675
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Brugia malayi beta-lactamase family protein 0.0273 0.0488 0.0666
Brugia malayi ecdysteroid receptor 0.0081 0.0111 0.0152
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Toxoplasma gondii histone lysine methyltransferase SET1 0.0692 0.1309 0.8096
Echinococcus multilocularis cpg binding protein 0.0386 0.0709 0.0709
Plasmodium falciparum topoisomerase I 0.085 0.1617 1
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Mycobacterium leprae Probable two-component sensor kinase 0.004 0.0031 0.0154
Brugia malayi ThiF family protein 0.0034 0.002 0.0028
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0397 0.0731 0.2167
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0048 0.0048
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Echinococcus multilocularis heat shock protein 0.0065 0.0081 0.0081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0082 0.0437
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.072 0.1362 0.747
Loa Loa (eye worm) hypothetical protein 0.0081 0.0113 0.0154
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0081 0.0111 0.0111
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.012 0.0188 0.0188
Echinococcus multilocularis lysosomal alpha glucosidase 0.0361 0.0659 0.0659
Loa Loa (eye worm) histone methyltransferase 0.0115 0.0178 0.0243
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0003 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0055 0.0145
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0071 0.0097
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.008 0.0433
Brugia malayi nuclear receptor RXR 0.0038 0.0028 0.0038
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0028 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0081 0.0111 0.0122
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0081 0.044
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Echinococcus multilocularis transcription factor btf3 0.0039 0.003 0.003
Brugia malayi hypothetical protein 0.1994 0.3857 0.5263
Echinococcus granulosus cpg binding protein 0.0386 0.0709 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Treponema pallidum chemotaxis histidine kinase (cheA) 0.004 0.0031 0.0081
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0637 0.12 0.1311
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1745 0.337 1
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0116 0.018 0.0983
Giardia lamblia Histone deacetylase 0.0297 0.0535 0.1429
Loa Loa (eye worm) RecQ helicase 0.0042 0.0037 0.005
Trypanosoma cruzi heat shock protein 90, putative 0.0065 0.0081 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus multilocularis dna polymerase eta 0.0147 0.0241 0.0241
Echinococcus granulosus microtubule associated protein 2 0.455 0.8859 0.968
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0112 0.0612
Brugia malayi PAS domain containing protein 0.0109 0.0167 0.0228
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0112 0.0172 0.1839
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0071 0.0188
Loa Loa (eye worm) intermediate filament protein 0.0174 0.0295 0.0402
Trypanosoma brucei chrX additional, unordered contigs 0.0037 0.0026 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0046 0.0043 0.0125
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0046 0.0043 0.022
Echinococcus multilocularis dnaJ subfamily C 6 0.007 0.0092 0.0092
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0449 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0055 0.0145
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0149 0.0246 0.1349
Loa Loa (eye worm) DnaJ domain-containing protein 0.007 0.0092 0.0125
Mycobacterium tuberculosis Probable two component sensor kinase 0.004 0.0031 0.009
Toxoplasma gondii histone deacetylase HDAC4 0.0242 0.0427 0.2639
Mycobacterium ulcerans beta-lactamase 0.0273 0.0488 0.2697
Mycobacterium ulcerans DNA gyrase subunit B 0.0377 0.0692 0.3826
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0046 0.0043 0.022
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Brugia malayi Histone deacetylase family protein 0.0344 0.0627 0.0855
Echinococcus granulosus para nitrobenzyl esterase 0.0637 0.12 0.1311
Loa Loa (eye worm) hypothetical protein 0.0075 0.01 0.0137
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Schistosoma mansoni DNA helicase recq1 0.0042 0.0037 0.004
Schistosoma mansoni nuclear hormone receptor 0.0081 0.0111 0.0122
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0955 0.1823 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0026 0.0066
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Mycobacterium ulcerans putative regulatory protein 0.0081 0.0112 0.0602
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.0037 0.0037
Plasmodium vivax heat shock protein 86, putative 0.0065 0.0081 0.0496
Brugia malayi cytochrome P450 0.0046 0.0043 0.0059
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0073 0.0079
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0048 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0081 0.0111 0.0122
Echinococcus granulosus neutral sphingomyelinase 0.0024 0.0001 0.0001
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0182 0.0539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0081 0.0111 0.0152
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.0012 0.003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.008 0.011 0.0293
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0008 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0138
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0028 0.0009 0.0022
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.009 0.009
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Schistosoma mansoni synaptojanin 0.0024 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.003 0.0077
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Toxoplasma gondii cathepsin CPL 0.0035 0.0022 0.0128
Brugia malayi conserved hypotetical protein 0.0038 0.0028 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0081 0.0111 0.0152
Brugia malayi Glycosyl hydrolases family 31 protein 0.0361 0.0659 0.09
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0111 0.0172 0.0188
Echinococcus granulosus single minded 2 0.0081 0.0112 0.0122
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0234 0.0412 0.0412
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0028 0.0028
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Loa Loa (eye worm) DR-78 0.0038 0.0028 0.0038
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0079 0.0109 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0082 0.0115 0.0304
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0052 0.0055 0.006
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Onchocerca volvulus 0.0363 0.0664 0.5532
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0081 0.0111 0.0122
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0155 0.0257 0.0257
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0112 0.0612
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.0522 0.0522
Echinococcus granulosus ras gtpase 0.0142 0.0232 0.0253
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0117 0.0183 0.0249
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.0522 0.0522
Entamoeba histolytica hypothetical protein 0.0092 0.0134 0.0356
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.009 0.0098
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.004 0.0031 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0009 0.0022
Schistosoma mansoni acetyl-CoA synthetase 0.0044 0.0039 0.0043
Brugia malayi CHE-14 protein 0.0043 0.0038 0.0052
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0037 0.0037
Plasmodium vivax ubiquitin activating enzyme, putative 0.0052 0.0055 0.0336
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0068 0.0087 0.0591
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0044 0.006
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.012 0.0188 0.0257
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0081 0.0111 0.0152
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0073 0.0079
Brugia malayi glutathione reductase 0.0046 0.0044 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0083 0.0219
Loa Loa (eye worm) hypothetical protein 0.0242 0.0427 0.0583
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0081 0.0111 0.0152
Loa Loa (eye worm) CYP4Cod1 0.0103 0.0155 0.0212
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0051 0.0054 0.0142
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.004 0.0031 0.0403
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Entamoeba histolytica hypothetical protein 0.0148 0.0244 0.065
Brugia malayi beta-lactamase 0.0273 0.0488 0.0666
Schistosoma mansoni nuclear receptor 0.0038 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0053 0.0057 0.0078
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0018 0.0105
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0044 0.0039 0.0043
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0052 0.0055 0.0055
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0119 0.0188 0.1024
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0055 0.0299
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0151 0.0151
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0028 0.0031
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0019
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0155 0.1295
Brugia malayi hypothetical protein 0.0257 0.0457 0.0623
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0188 0.05
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.005
Schistosoma mansoni microtubule-associated protein tau 0.455 0.8859 0.968
Onchocerca volvulus 0.0028 0.0009 0.0076
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0046 0.0043 0.0125
Schistosoma mansoni inositol monophosphatase 0.0159 0.0265 0.029
Brugia malayi follicle stimulating hormone receptor 0.052 0.0972 0.1326
Trypanosoma cruzi histone deacetylase 1, putative 0.0297 0.0535 0.293
Onchocerca volvulus 0.0273 0.0488 0.407
Onchocerca volvulus 0.0035 0.0022 0.0179
Onchocerca volvulus Huntingtin homolog 0.0257 0.0457 0.3804
Echinococcus granulosus neuropeptide receptor A26 0.0978 0.1868 0.2041
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0042
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.0093 0.0248
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.009 0.0237
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0046 0.0043 0.0125
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0134 0.0217 0.1183
Echinococcus granulosus synaptojanin 1 0.0024 0.0001 0.0001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0071 0.0385
Echinococcus multilocularis nmda type glutamate receptor 0.1954 0.3779 0.3779
Brugia malayi polk-prov protein 0.0065 0.0081 0.0111
Entamoeba histolytica DNA topoisomerase III, putative 0.0034 0.0021 0.0053
Brugia malayi kinase, mitochondrial precursor 0.004 0.0031 0.0042
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0046 0.0043 0.022
Echinococcus granulosus sentrin specific protease 8 0.0071 0.0093 0.0102
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0071 0.0385
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0026 0.0159
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0552 0.1034 0.1034
Brugia malayi Glycosyl hydrolases family 31 protein 0.008 0.011 0.015
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0086 0.0094
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0082 0.0082
Brugia malayi SET domain containing protein 0.0033 0.0019 0.0025
Plasmodium vivax hypothetical protein, conserved 0.004 0.0031 0.0188
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0246 0.0336
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0377 0.0692 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0154 0.0168
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0119 0.0188 0.0188
Onchocerca volvulus Putative neutral sphingomyelinase 0.0024 0.0001 0.0007
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0052
Loa Loa (eye worm) histone deacetylase 3 0.0297 0.0535 0.073
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0099 0.0108
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.004 0.0031 0.009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0022 0.0022
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0109 0.0149
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0071 0.0385
Trichomonas vaginalis alpha-glucosidase, putative 0.008 0.011 0.0293
Trypanosoma brucei unspecified product 0.0083 0.0116 0.0629
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0155 0.0155
Onchocerca volvulus 0.0035 0.0022 0.0179
Echinococcus multilocularis beta LACTamase domain containing family member 0.0273 0.0488 0.0488
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0048 0.0256
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0008 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0155 0.0212
Leishmania major DNA damage repair protein, putative 0.0037 0.0026 0.0141
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0137 0.0221 0.0654
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0034 0.002 0.0022
Onchocerca volvulus 0.0174 0.0295 0.2457
Entamoeba histolytica acyl-coA synthetase, putative 0.0149 0.0246 0.0656
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0037 0.004
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0159 0.0265 0.145
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0115 0.0179 0.0179
Echinococcus multilocularis acetylcholinesterase 0.3769 0.733 0.733
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0134 0.0217 0.1183
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0018 0.0018
Loa Loa (eye worm) carboxylesterase 0.0637 0.12 0.1637
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0116 0.018 0.048
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0044 0.0039 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0042 0.0037 0.004
Loa Loa (eye worm) hypothetical protein 0.0079 0.0109 0.0149
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0022 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Schistosoma mansoni tsg101-related 0.0149 0.0246 0.0269
Echinococcus granulosus expressed protein 0.0066 0.0083 0.009
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.008 0.011 0.0677
Leishmania major hypothetical protein, conserved 0.0081 0.0112 0.0612
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Toxoplasma gondii DNA topoisomerase family protein 0.0034 0.0021 0.0123
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Echinococcus granulosus dnaJ subfamily B 0.4699 0.9152 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0018 0.005
Loa Loa (eye worm) glutaminase 2 0.0291 0.0524 0.0715
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0009 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Trichomonas vaginalis protein kinase inhibitor, putative 0.007 0.0092 0.0243
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0397 0.0731 0.4045
Brugia malayi Protein kinase domain containing protein 0.0048 0.0048 0.0065
Trypanosoma cruzi DNA damage repair protein, putative 0.0037 0.0026 0.0141
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Onchocerca volvulus 0.0174 0.0295 0.2457
Loa Loa (eye worm) hypoxia-induced factor 1 0.0338 0.0615 0.0839
Trypanosoma brucei unspecified product 0.0141 0.023 0.1255
Giardia lamblia DNA topoisomerase II 0.0602 0.1132 0.3029
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0039 0.0029 0.0076
Schistosoma mansoni transcription factor btf3 0.0039 0.003 0.0032
Mycobacterium ulcerans putative regultory protein 0.004 0.0031 0.0154
Schistosoma mansoni endoplasmin 0.0065 0.0081 0.0088
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0081 0.0111 0.0122
Mycobacterium tuberculosis Probable sensor protein KdpD 0.004 0.0031 0.009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0246 0.0656
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0034 0.0021 0.0023
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0116 0.018 0.0197
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0039 0.0103
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0081 0.0111 0.0152
Echinococcus granulosus Polycystic kidney disease protein 0.0066 0.0083 0.0091
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Brugia malayi Endoplasmin precursor 0.0065 0.0081 0.011
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0046 0.0043 0.0125
Loa Loa (eye worm) hypothetical protein 0.0081 0.0112 0.0153
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0028 0.0038
Schistosoma mansoni histone deacetylase 0.0297 0.0535 0.0584
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.0045 0.0049
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0046 0.0043 0.022
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0046 0.0043 0.0125
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0217 0.0296
Loa Loa (eye worm) oxidoreductase 0.0044 0.0039 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0115 0.0179 0.0244
Toxoplasma gondii histone deacetylase HDAC1 0.0344 0.0627 0.3875
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0077
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0034 0.0021 0.0023
Echinococcus multilocularis glutamate receptor 2 0.0079 0.0109 0.0109
Brugia malayi Melibiase family protein 0.0074 0.0099 0.0135
Schistosoma mansoni hypothetical protein 0.0115 0.0179 0.0195
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0083 0.0091
Brugia malayi latrophilin 2 splice variant baaae 0.0248 0.044 0.06
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0081 0.0111 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Schistosoma mansoni rab6-interacting 0.0066 0.0083 0.0091
Trichomonas vaginalis inositol monophosphatase, putative 0.0159 0.0265 0.0707
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0637 0.12 0.1637
Trypanosoma brucei unspecified product 0.0083 0.0116 0.0629
Brugia malayi STAT protein, DNA binding domain containing protein 0.0154 0.0255 0.0347
Echinococcus granulosus zinc finger protein 0.0043 0.0038 0.0042
Plasmodium vivax protein kinase Crk2 0.0048 0.0048 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0086 0.0458
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0079 0.0109 0.0149
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.023 0.1255
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0131 0.0179
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0141
Plasmodium vivax DNA gyrase subunit B, putative 0.0377 0.0692 0.4274
Schistosoma mansoni glutamate receptor NMDA 0.1637 0.3157 0.345
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Entamoeba histolytica deoxycytidyl transferase, putative 0.012 0.0188 0.0502
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0155 0.0848
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0637 0.12 0.3559
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0028 0.0028
Schistosoma mansoni glutamate receptor AMPA 0.0155 0.0257 0.0281
Toxoplasma gondii histone deacetylase HDAC5 0.0242 0.0427 0.2639
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.004 0.0031 0.0154
Echinococcus granulosus neuropeptide s receptor 0.0978 0.1868 0.2041
Brugia malayi metabotropic glutamate receptor type 2 0.0079 0.0109 0.0149
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.006 0.0066
Schistosoma mansoni retinoic acid receptor RXR 0.0081 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0159 0.0471
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0326 0.0591 0.8539
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.0409 0.0559
Trypanosoma brucei DNA polymerase kappa, putative 0.0127 0.0202 0.1103
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0079 0.0109 0.0109
Loa Loa (eye worm) Ulp1 protease 0.0071 0.0093 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0129 0.0704
Echinococcus granulosus bloom syndrome protein 0.0042 0.0037 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Echinococcus multilocularis histone deacetylase 6 0.0344 0.0627 0.0627
Plasmodium falciparum histone deacetylase 1 0.0297 0.0535 0.3304
Schistosoma mansoni hypothetical protein 0.0248 0.044 0.0481
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0234 0.0412 0.0451
Loa Loa (eye worm) hypothetical protein 0.0132 0.0213 0.029
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0119 0.0188 0.0205
Brugia malayi beta-lactamase family protein 0.0273 0.0488 0.0666
Echinococcus multilocularis microtubule associated protein 2 0.455 0.8859 0.8859
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0034 0.0021 0.0096
Echinococcus granulosus beta LACTamase domain containing family member 0.0273 0.0488 0.0534
Trypanosoma cruzi DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0046 0.0043 0.022
Plasmodium falciparum telomerase reverse transcriptase 0.057 0.107 0.6618
Echinococcus granulosus histone deacetylase 6 0.0344 0.0627 0.0685
Brugia malayi Carboxylesterase family protein 0.3769 0.733 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0025 0.0025
Brugia malayi jmjC domain containing protein 0.0091 0.0131 0.0179
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0022 0.0113
Echinococcus multilocularis BC026374 protein (S09 family) 0.0637 0.12 0.12
Schistosoma mansoni kinase 0.0053 0.0058 0.0063
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0048 0.0256
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0608 0.1143 0.6267
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0034 0.0021 0.0023
Leishmania major DNA topoisomerase IB, large subunit 0.085 0.1617 0.8867
Schistosoma mansoni histone deacetylase 1 2 3 0.0242 0.0427 0.0467
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0115 0.0304
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.0522 0.057
Echinococcus granulosus neuroligin 0.0637 0.12 0.1311
Schistosoma mansoni ap endonuclease 0.0119 0.0188 0.0205
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0127 0.0202 0.0597
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0377 0.0692 0.4274
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0397 0.0731 0.1954
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Brugia malayi N-terminal motif family protein 0.0394 0.0724 0.0988
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0159 0.0471
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0071 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Leishmania major DNA polymerase kappa, putative 0.0127 0.0202 0.1103
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0042 0.0037 0.004
Echinococcus multilocularis heat shock protein 90 0.0025 0.0003 0.0003
Trichomonas vaginalis penicillin-binding protein, putative 0.0273 0.0488 0.1305
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0276 0.0495 0.0541
Brugia malayi MAP kinase sur-1 0.006 0.0071 0.0097
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0081 0.0111 0.0111
Brugia malayi ImpB/MucB/SamB family protein 0.0147 0.0241 0.0329
Loa Loa (eye worm) hypothetical protein 0.0101 0.0151 0.0206
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0155 0.017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0081 0.0111 0.0111
Echinococcus multilocularis p2X purinoceptor 4 0.0133 0.0214 0.0214
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.004 0.0031 0.0154
Mycobacterium tuberculosis Two component sensor kinase MprB 0.004 0.0031 0.009
Loa Loa (eye worm) hypothetical protein 0.0149 0.0246 0.0336
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0071 0.0078
Brugia malayi hypothetical protein 0.0305 0.0551 0.0752
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0079 0.0108
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0037 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0115 0.0179 0.0179
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0111 0.0172 0.0172
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0037 0.005
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.004 0.0031 0.0166
Echinococcus granulosus dual specificity 0.0098 0.0145 0.0158
Echinococcus granulosus RUN 0.0066 0.0083 0.0091
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0086 0.0094
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.008 0.011 0.0293
Mycobacterium ulcerans esterase/lipase LipP 0.0273 0.0488 0.2697
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0012 0.003
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0217 0.0237
Brugia malayi hypothetical protein 0.0038 0.0028 0.0038
Echinococcus granulosus histone deacetylase 3 0.0297 0.0535 0.0584
Echinococcus multilocularis RUN 0.0066 0.0083 0.0083
Schistosoma mansoni flap endonuclease-1 0.0025 0.0003 0.0003
Brugia malayi DNA topoisomerase III beta-1 0.0034 0.0021 0.0028
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.004 0.0031 0.0154
Echinococcus multilocularis transfer RNA-Lys 0.0081 0.0112 0.0112
Loa Loa (eye worm) histone deacetylase 1 0.0297 0.0535 0.073
Echinococcus granulosus survival motor neuron protein 1 0.1994 0.3857 0.4215
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0081 0.0111 0.0152
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0071 0.0385
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0024 0.0001 0.0001
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0098 0.0145 0.0791
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0396 0.0729 0.0994
Plasmodium falciparum histone deacetylase 2 0.0344 0.0627 0.3875
Brugia malayi Inositol-1 0.0159 0.0265 0.0362
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0081 0.0214
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Entamoeba histolytica hypothetical protein 0.0079 0.0109 0.029
Brugia malayi Carboxylesterase family protein 0.0637 0.12 0.1637
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0081 0.0111 0.0152
Trypanosoma brucei DNA topoisomerase III, putative 0.0034 0.0021 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0022 0.0055
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0637 0.12 0.1311
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trichomonas vaginalis sucrase-isomaltase, putative 0.008 0.011 0.0293
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0048 0.0256
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0001 0.0001
Loa Loa (eye worm) ICD-1 protein 0.0039 0.003 0.004
Plasmodium vivax SET domain protein, putative 0.0041 0.0034 0.0207
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0039 0.0029 0.004
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0046 0.0043 0.0125
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0009 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Plasmodium vivax DNA topoisomerase 3, putative 0.0034 0.0021 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0018 0.0018
Entamoeba histolytica histone deacetylase, putative 0.0297 0.0535 0.1429
Plasmodium vivax DNA repair protein REV1, putative 0.0037 0.0026 0.0159
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0028 0.0038
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0151 0.0401
Onchocerca volvulus 0.0273 0.0488 0.407
Loa Loa (eye worm) steroid hormone receptor 0.0081 0.0111 0.0152
Entamoeba histolytica cysteine protease, putative 0.0035 0.0022 0.0055
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0076
Brugia malayi Glutamate receptor 1 precursor 0.0155 0.0257 0.035
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.029 0.0522 0.0712
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0008 0.0008
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0018 0.0024
Schistosoma mansoni neuroligin 3 (S09 family) 0.0637 0.12 0.1311
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0046 0.0043 0.0231
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0022 0.0113
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0044 0.0039 0.0115
Schistosoma mansoni terminal deoxycytidyl transferase 0.012 0.0188 0.0206
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0039 0.02
Brugia malayi GTP-binding protein, identical 0.0142 0.0232 0.0316
Trichomonas vaginalis histone deacetylase, putative 0.0297 0.0535 0.1429
Entamoeba histolytica hypothetical protein 0.0045 0.0042 0.0109
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.0221
Leishmania major cathepsin L-like protease 0.0035 0.0022 0.0113
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0028 0.0031
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0034 0.0021 0.0109
Mycobacterium tuberculosis Probable esterase LipL 0.0273 0.0488 0.1447
Brugia malayi tailless protein 0.0038 0.0028 0.0038
Echinococcus granulosus expressed conserved protein 0.0095 0.0139 0.0152
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0079 0.0109 0.0149
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0116 0.018 0.0983
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0156
Loa Loa (eye worm) hypothetical protein 0.0084 0.0118 0.0161
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0086 0.0086
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0034 0.0021 0.0028
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0217 0.0296
Trichomonas vaginalis rotamase, putative 0.0066 0.0083 0.0219
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trypanosoma brucei developmentally regulated phosphoprotein 0.004 0.0031 0.0166
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.0039 0.02
Loa Loa (eye worm) heat shock protein 90 0.0065 0.0081 0.011
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Echinococcus multilocularis nmda type glutamate receptor 0.1482 0.2854 0.2854
Treponema pallidum fructose-bisphosphate aldolase 0.1933 0.3737 1
Plasmodium vivax DNA topoisomerase II, putative 0.0642 0.121 0.7482
Schistosoma mansoni nocturnin 0.0024 0.0001 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0082 0.009
Schistosoma mansoni inositol monophosphatase 0.0159 0.0265 0.029
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0377 0.0692 0.1849
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0092 0.0134 0.1116
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0048 0.0289
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0048 0.0065
Trichomonas vaginalis endoplasmin, putative 0.0053 0.0057 0.015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0035 0.0035
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0026 0.0138
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0436 0.0807 0.6723
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0044 0.0039 0.02
Trypanosoma cruzi extracellular receptor, putative 0.0079 0.0109 0.0594
Mycobacterium tuberculosis Conserved protein 0.0273 0.0488 0.1447
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0116 0.018 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0071 0.0078
Leishmania major cathepsin L-like protease 0.0132 0.0212 0.116
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.0115
Leishmania major DNA polymerase eta, putative 0.0064 0.0079 0.0429
Brugia malayi Bromodomain containing protein 0.0107 0.0163 0.0222
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0086 0.0094
Schistosoma mansoni hypothetical protein 0.0066 0.0083 0.0091
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0142 0.0232 0.0687
Brugia malayi jmjC domain containing protein 0.0068 0.0086 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0155 0.0414
Toxoplasma gondii melibiase subfamily protein 0.0111 0.0172 0.1058
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.0235
Brugia malayi histone deacetylase 3 (HD3) 0.0297 0.0535 0.073
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0046 0.0043 0.022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0273 0.0488 0.0534
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.004 0.0031 0.009
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0109 0.0149
Echinococcus granulosus tumor susceptibility gene 101 protein 0.022 0.0384 0.0419
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0066
Mycobacterium tuberculosis Probable hydrolase 0.0273 0.0488 0.1447
Trypanosoma brucei heat shock protein, putative 0.0065 0.0081 0.044
Loa Loa (eye worm) hypothetical protein 0.0297 0.0535 0.073
Mycobacterium tuberculosis Cell division protein FtsZ 0.0326 0.0591 0.1752
Loa Loa (eye worm) DNA topoisomerase III 0.0034 0.0021 0.0028
Echinococcus multilocularis expressed conserved protein 0.0095 0.0139 0.0139
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0028 0.0031
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0046 0.0043 0.022
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0048 0.0048
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0064 0.008 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0026 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0028 0.0073
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Onchocerca volvulus Huntingtin homolog 0.0257 0.0457 0.3804
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0044 0.0039 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Loa Loa (eye worm) cysteine protease 0.0035 0.0022 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0048 0.0052
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0276 0.0495 0.0495
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0149 0.0246 0.1349
Onchocerca volvulus 0.0066 0.0083 0.0694
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0044 0.0039 0.02
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0039 0.0212
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0022 0.0023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0099 0.0108
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0038 0.0042
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0038
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0081 0.0441
Brugia malayi hypothetical protein 0.0066 0.0083 0.0114
Schistosoma mansoni glutamate receptor kainate 0.0155 0.0257 0.0281
Toxoplasma gondii exonuclease III APE 0.0119 0.0188 0.1155
Onchocerca volvulus 0.0038 0.0028 0.0234
Brugia malayi nuclear hormone receptor 0.0038 0.0028 0.0038
Toxoplasma gondii hypothetical protein 0.0154 0.0255 0.1574
Onchocerca volvulus 0.0097 0.0143 0.1193
Trichomonas vaginalis Sentrin-specific protease, putative 0.0071 0.0093 0.0248
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0297 0.0535 0.1429
Echinococcus multilocularis glutamate receptor NMDA 0.1402 0.2698 0.2698
Onchocerca volvulus 0.0209 0.0362 0.3015
Echinococcus multilocularis tyrosine kinase 0.0079 0.0109 0.0109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0039 0.0029 0.0076
Loa Loa (eye worm) glutaminase 0.0291 0.0524 0.0715
Plasmodium vivax vivapain-2 0.0035 0.0022 0.0128
Loa Loa (eye worm) hypothetical protein 0.0305 0.0551 0.0752
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0134 0.0183
Chlamydia trachomatis DNA gyrase subunit A 0.0137 0.0221 0.2555
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0034 0.0021 0.0251
Brugia malayi hypothetical protein 0.0066 0.0083 0.0114
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0018 0.0105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0081 0.0111 0.0122
Schistosoma mansoni ap endonuclease 0.0119 0.0188 0.0205
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0111 0.0172 0.0188
Schistosoma mansoni gliotactin 0.0637 0.12 0.1311
Onchocerca volvulus 0.0033 0.0019 0.0154
Echinococcus granulosus heat shock protein 0.0065 0.0081 0.0088
Trypanosoma brucei ISWI complex protein 0.0038 0.0028 0.015
Schistosoma mansoni tyrosine kinase 0.0079 0.0109 0.0119
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0083 0.0114
Schistosoma mansoni alpha-glucosidase 0.031 0.0561 0.0613
Trypanosoma brucei DNA damage repair protein, putative 0.0037 0.0026 0.0141
Leishmania major telomerase reverse transcriptase, putative 0.0092 0.0134 0.073
Loa Loa (eye worm) CXXC zinc finger family protein 0.0363 0.0664 0.0906
Trypanosoma brucei cytochrome P450, putative 0.0103 0.0155 0.0849
Brugia malayi Intermediate filament tail domain containing protein 0.0174 0.0295 0.0402
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0022 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0022 0.0055
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0155 0.0212
Mycobacterium leprae putative cytochrome p450 0.0046 0.0043 0.022
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0039 0.0029 0.0156
Echinococcus granulosus GPCR family 2 0.0115 0.0179 0.0195
Toxoplasma gondii heat shock protein 90, putative 0.0065 0.0081 0.0496
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0038
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0044 0.0039 0.0115
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0044 0.0039 0.0115
Trypanosoma cruzi cytochrome P450, putative 0.0103 0.0155 0.0849
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0082 0.0446
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1933 0.3737 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0071 0.0385
Toxoplasma gondii RNA-directed DNA polymerase 0.0092 0.0134 0.0824
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0046 0.0043 0.0125
Giardia lamblia DINP protein human, muc B family 0.0127 0.0202 0.0538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0212 0.116
Mycobacterium ulcerans DNA topoisomerase I 0.0034 0.0021 0.0096
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0217 0.0296
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0008 0.0047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0273 0.0488 0.0666
Trichomonas vaginalis D-aminoacylase, putative 0.0273 0.0488 0.1305
Plasmodium falciparum heat shock protein 90 0.0065 0.0081 0.0496
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0165 0.0277 0.152
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0119 0.0188 0.2675
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0013 0.0065
Mycobacterium ulcerans hypothetical protein 0.0273 0.0488 0.2697
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0174 0.0295 0.0402
Loa Loa (eye worm) hypothetical protein 0.0081 0.0111 0.0152
Onchocerca volvulus 0.0035 0.0022 0.0179
Trypanosoma cruzi histone deacetylase, putative 0.0344 0.0627 0.3436
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0029
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0048 0.0256
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0039 0.0054
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.008 0.011 0.015
Echinococcus multilocularis survival motor neuron protein 1 0.1994 0.3857 0.3857
Mycobacterium leprae conserved hypothetical protein 0.0273 0.0488 0.2697
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0022 0.0128
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.012 0.0188 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0155 0.017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0081 0.0111 0.0152
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Echinococcus granulosus histone deacetylase 1 0.0297 0.0535 0.0584
Echinococcus multilocularis ecdysone induced protein 78C 0.0081 0.0111 0.0111
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.004 0.0031 0.0166
Echinococcus granulosus carboxylesterase 5A 0.3769 0.733 0.8009
Toxoplasma gondii DNA topoisomerase I, putative 0.085 0.1617 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0115 0.0178 0.0178
Toxoplasma gondii cytochrome p450 superfamily protein 0.0046 0.0043 0.0261
Echinococcus granulosus tar DNA binding protein 0.0135 0.0217 0.0237
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.009 0.0098
Onchocerca volvulus 0.0035 0.0022 0.0179
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.004 0.0031 0.0154
Schistosoma mansoni P2X receptor subunit 0.0133 0.0214 0.0234
Onchocerca volvulus 0.0264 0.047 0.3917
Echinococcus multilocularis ras gtpase 0.0142 0.0232 0.0232
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0028 0.0031
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.004 0.0031 0.0031
Mycobacterium ulcerans two component regulator - sensor kinase 0.004 0.0031 0.0154
Trypanosoma brucei DNA polymerase eta, putative 0.0147 0.0241 0.1317
Plasmodium vivax histone deacetylase, putative 0.0242 0.0427 0.2639
Onchocerca volvulus 0.0637 0.12 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.004 0.0243
Loa Loa (eye worm) ThiF family protein 0.0034 0.002 0.0028
Echinococcus granulosus glutamate receptor 2 0.0234 0.0412 0.0451
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.016 0.0473
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0066 0.009
Echinococcus granulosus FTZ F1 alpha 0.0081 0.0111 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0148 0.0243 0.1329
Schistosoma mansoni cpg binding protein 0.0386 0.0709 0.0774
Loa Loa (eye worm) cytochrome P450 family protein 0.0103 0.0155 0.0212
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0018 0.0024
Mycobacterium tuberculosis Conserved protein 0.004 0.0031 0.009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0037 0.005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0273 0.0488 0.0666
Toxoplasma gondii heat shock protein HSP90 0.0065 0.0081 0.0496
Leishmania major heat shock protein 83-1 0.0065 0.0081 0.044
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0397 0.0731 1
Echinococcus granulosus histone deacetylase 0.0344 0.0627 0.0685
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0018 0.0093
Mycobacterium ulcerans acetyl-CoA synthetase 0.0044 0.0039 0.02
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0159 0.0471
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0044 0.0039 0.0115
Leishmania major hypothetical protein, conserved 0.0273 0.0488 0.2675
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0001 0.0001
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0029 0.0011 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.0039 0.02
Schistosoma mansoni glutamate receptor AMPA 0.0155 0.0257 0.0281

Activities

Activity type Activity value Assay description Source Reference
EC1000 (binding) = 13 nM Inhibition of HDAC4 assessed as induction of p21 promotor activity by cell based assay ChEMBL. 20045316
IC50 (binding) = 12 nM Inhibition of HDAC4 ChEMBL. 20045316
IC50 (binding) = 12 nM Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIPR method ChEMBL. 25022972
IC50 (binding) = 25 nM Inhibition of HDAC1 ChEMBL. 20045316
IC50 (binding) = 25 nM Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIPR method ChEMBL. 25022972
IC50 (binding) = 340 nM Inhibition of HDAC6 ChEMBL. 20045316
IC50 (binding) = 340 nM Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIPR method ChEMBL. 25022972

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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