Detailed information for compound 402275

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 3554.07 | Formula: C157H262N50O44
  • H donors: 51 H acceptors: 46 LogP: -16.85 Rotable bonds: 142
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCC[C@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H]1CCC(=O)NCCCC[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)CCCC)CCC(=O)O)C(=O)N[C@H]([C@H](CC)C)C(=O)N)CCCCN)CCCN=C(N)N)CC(=O)N)CO)Cc1nc[nH]c1)C)CCC(=O)N)CCC(=O)N)C)CC(C)C)CCC(=O)N)CCC(=O)O)C)CCCN=C(N)N)C)NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC([C@H](NC(=O)[C@H](Cc1ccccc1)N)Cc1nc[nH]c1)O)CC(C)C)CC(C)C)CCCN=C(N)N)CCC(=O)O)CC(C)C)CCC(=O)O
  • InChi: 1S/C157H262N50O44/c1-19-22-36-91(186-142(239)104(49-57-121(218)219)197-148(245)109(67-80(10)11)204-154(251)123(81(12)13)206-145(242)105(50-58-122(220)221)196-137(234)97(42-33-63-176-157(169)170)190-147(244)107(65-78(6)7)201-149(246)108(66-79(8)9)202-150(247)111(70-89-73-172-76-178-89)199-130(227)90(159)68-87-34-25-24-26-35-87)131(228)179-83(15)126(223)183-95(40-31-61-174-155(165)166)132(229)180-84(16)127(224)185-102(47-55-119(214)215)140(237)193-100(45-53-116(162)211)143(240)200-106(64-77(4)5)146(243)182-85(17)128(225)184-99(44-52-115(161)210)138(235)192-98(43-51-114(160)209)133(230)181-86(18)129(226)198-110(69-88-72-171-75-177-88)151(248)205-113(74-208)153(250)203-112(71-117(163)212)152(249)191-96(41-32-62-175-156(167)168)136(233)188-93(38-27-29-59-158)135(232)194-101-46-54-118(213)173-60-30-28-39-94(144(241)207-124(125(164)222)82(14)21-3)189-141(238)103(48-56-120(216)217)195-134(231)92(37-23-20-2)187-139(101)236/h24-26,34-35,72-73,75-86,90-113,123-124,150,202,208,247H,19-23,27-33,36-71,74,158-159H2,1-18H3,(H2,160,209)(H2,161,210)(H2,162,211)(H2,163,212)(H2,164,222)(H,171,177)(H,172,178)(H,173,213)(H,179,228)(H,180,229)(H,181,230)(H,182,243)(H,183,223)(H,184,225)(H,185,224)(H,186,239)(H,187,236)(H,188,233)(H,189,238)(H,190,244)(H,191,249)(H,192,235)(H,193,237)(H,194,232)(H,195,231)(H,196,234)(H,197,245)(H,198,226)(H,199,227)(H,200,240)(H,201,246)(H,203,250)(H,204,251)(H,205,248)(H,206,242)(H,207,241)(H,214,215)(H,216,217)(H,218,219)(H,220,221)(H4,165,166,174)(H4,167,168,175)(H4,169,170,176)/t82-,83-,84-,85-,86-,90+,91-,92+,93-,94+,95-,96-,97-,98-,99-,100-,101+,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,123-,124-,150?/m0/s1
  • InChiKey: PGBBXVOOJOOHFT-NIFRNNIESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0758 0.0641 0.0641
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0001 0.0004
Brugia malayi Cation transporter family protein 0.0063 0.0038 0.004
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0029 0.0029
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0264 0.0212 0.0739
Brugia malayi cathepsin Z-like cysteine proteinase 0.0426 0.0353 0.0374
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Entamoeba histolytica calmodulin, putative 0.0029 0.0008 0.0048
Mycobacterium tuberculosis Probable peptidase 0.0592 0.0497 0.457
Brugia malayi mbt repeat family protein 0.0053 0.0029 0.0031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0021 0.0022
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0015 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0013 0.0078
Onchocerca volvulus 0.1915 0.1647 1
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0073 0.0046 0.0049
Loa Loa (eye worm) hypothetical protein 0.0574 0.0481 0.051
Brugia malayi beta-lactamase family protein 0.0035 0.0013 0.0014
Echinococcus granulosus cathepsin l1 0.1915 0.1647 0.2717
Trichomonas vaginalis centrin, putative 0.0029 0.0008 0.0048
Onchocerca volvulus 0.0024 0.0003 0.0018
Leishmania major protein kinase, putative 0.0035 0.0013 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0001 0.0003
Trypanosoma cruzi oligopeptidase b 0.0592 0.0497 0.1731
Echinococcus multilocularis neuropeptide s receptor 0.0758 0.0641 0.1058
Brugia malayi photoreceptor-specific nuclear receptor 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.002 0 0.000009889
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.2752 0.2375 0.2516
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Onchocerca volvulus 0.0093 0.0064 0.0385
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0029 0.0008 0.0027
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0015 0.009
Echinococcus granulosus cysteine protease 0.103 0.0878 0.1448
Brugia malayi Pleckstrin Homology Domain 0.0054 0.003 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1915 0.1647 1
Schistosoma mansoni cathepsin F (C01 family) 0.1311 0.1123 0.1123
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0061 0.0035 0.0037
Echinococcus multilocularis Regulator of G protein signaling 20 0.0037 0.0015 0.0025
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.0086 0.0522
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0003 0.0005
Schistosoma mansoni reticulocalbin 0.0029 0.0008 0.0008
Echinococcus granulosus cathepsin L cysteine protease 0.103 0.0878 0.1448
Entamoeba histolytica diacylglycerol kinase, putative 0.0054 0.003 0.018
Trypanosoma brucei oligopeptidase b 0.0592 0.0497 0.2876
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0081 0.0053 0.1041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0006 0.0006
Onchocerca volvulus 0.0029 0.0008 0.0048
Brugia malayi calcium-binding protein 0.0029 0.0008 0.0008
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0029 0.01
Trypanosoma cruzi cruzipain precursor, putative 0.2007 0.1727 0.6011
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0031 0.005
Trypanosoma cruzi ISWI complex protein 0.0035 0.0013 0.0044
Echinococcus granulosus myotubularin protein 13 0.0054 0.003 0.0049
Loa Loa (eye worm) hypothetical protein 0.3325 0.2873 0.3043
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0592 0.0497 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0015 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.103 0.0878 0.5329
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0007
Toxoplasma gondii EF hand domain-containing protein 0.0029 0.0008 0.0048
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0426 0.0353 0.0353
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0073 0.0046 0.028
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.0064 0.0105
Loa Loa (eye worm) glutaminase 0.026 0.0209 0.0221
Loa Loa (eye worm) TK/ROR protein kinase 0.0029 0.0008 0.0008
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.0475
Echinococcus granulosus peptide allatostatin:somatostatin 0.0758 0.0641 0.1058
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0004 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0084 0.1662
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0758 0.0641 0.1058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Schistosoma mansoni hypothetical protein 0.0076 0.0049 0.0049
Echinococcus granulosus jun protein 0.0081 0.0053 0.0088
Brugia malayi Cytochrome P450 family protein 0.0083 0.0055 0.0058
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0001 0.0007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0758 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Loa Loa (eye worm) cathepsin B 0.1323 0.1132 0.12
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0081 0.0053 0.0184
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0001 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.1915 0.1647 0.1647
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0244 0.0195 0.0677
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Trypanosoma brucei hypothetical protein 0.0073 0.0046 0.0263
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0101 0.0071 0.0075
Echinococcus granulosus geminin 0.0355 0.0292 0.0481
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0263
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0001 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.103 0.0878 0.093
Leishmania major hypothetical protein, conserved 0.0021 0.0001 0.0001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0001 0.0004
Brugia malayi steroid hormone receptor 0.005 0.0026 0.0027
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0001 0.0006
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0426 0.0353 0.2144
Giardia lamblia Cathepsin B precursor 0.0426 0.0353 0.3119
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.0475
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0081 0.0053 0.0184
Loa Loa (eye worm) hypothetical protein 0.0106 0.0074 0.0079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0081 0.0053 0.0053
Onchocerca volvulus 0.0758 0.0641 0.3893
Brugia malayi RhoGAP domain containing protein 0.0054 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0005
Echinococcus granulosus G protein coupled receptor 139 0.0758 0.0641 0.1058
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0008 0.0012
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0007 0.0058
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0007 0.0039
Echinococcus granulosus transient receptor potential gamma protein 0.0101 0.0071 0.0116
Brugia malayi hypothetical protein 0.0076 0.0049 0.0052
Entamoeba histolytica calcium binding family protein 0.0029 0.0008 0.0048
Loa Loa (eye worm) hypothetical protein 0.0357 0.0293 0.031
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0063 0.0038 0.0062
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0039 0.0016 0.0027
Brugia malayi Calmodulin-like protein 0.0029 0.0008 0.0008
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0026 0.0026
Echinococcus multilocularis transient receptor potential gamma protein 0.0101 0.0071 0.0116
Trypanosoma brucei proteasome beta 6 subunit 0.0063 0.0037 0.021
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0031 0.005
Mycobacterium ulcerans beta-lactamase 0.0035 0.0013 0.0255
Toxoplasma gondii thioredoxin reductase 0.0046 0.0022 0.0135
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0013 0.0078
Echinococcus multilocularis EF hand domain containing family member A2 0.0029 0.0008 0.0013
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0035 0.0013 0.0022
Schistosoma mansoni cellular tumor antigen P53 0.0147 0.0111 0.0111
Brugia malayi prolyl oligopeptidase family protein 0.0176 0.0136 0.0144
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0029 0.0574
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1271 0.1088 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0007 0.0126
Brugia malayi Bromodomain containing protein 0.017 0.013 0.0138
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0039 0.0016 0.0027
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0015 0.0052
Schistosoma mansoni protein kinase C mu 0.0054 0.003 0.003
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0008 0.0047
Toxoplasma gondii exonuclease III APE 0.0021 0.0001 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.2007 0.1727 0.6011
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.103 0.0878 0.0878
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0006 0.0055
Brugia malayi Variant SH3 domain containing protein 0.0054 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Trypanosoma cruzi calmodulin, putative 0.0029 0.0008 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Schistosoma mansoni reticulocalbin 0.0029 0.0008 0.0008
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0015 0.009
Brugia malayi cathepsin L precursor 0.0426 0.0353 0.0374
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0084 0.0767
Brugia malayi Protein kinase domain containing protein 0.006 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0073 0.0046 0.0263
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0054 0.003 0.0031
Schistosoma mansoni retinoic acid receptor RXR 0.005 0.0026 0.0026
Plasmodium falciparum glutathione reductase 0.0046 0.0022 0.0135
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0063 0.0104
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Brugia malayi Serotonin receptor 0.5061 0.4382 0.4642
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0007 0.0126
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0015 0.0052
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.006 0.0035 0.0058
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0063 0.0038 0.004
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.0249 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0068 0.0068
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0015 0.0016
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0015 0.0025
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0357 0.0293 0.102
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0063 0.0038 0.0062
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0029 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Echinococcus granulosus Transglutaminase 0.0034 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0012 0.0019
Giardia lamblia PHD finger protein 15 0.0033 0.0011 0.0095
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.005 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Echinococcus multilocularis acylamino acid releasing enzyme 0.0176 0.0136 0.0224
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0029 0.0008 0.0048
Leishmania major centrin, putative,caltractin, putative 0.0029 0.0008 0.0041
Loa Loa (eye worm) neuropeptide F receptor 0.0758 0.0641 0.0679
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0001 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0013 0.0013
Leishmania major i/6 autoantigen-like protein 0.0029 0.0008 0.0041
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0015 0.0016
Plasmodium falciparum amino acid transporter, putative 0.0536 0.0448 0.272
Trichomonas vaginalis centrin, putative 0.0029 0.0008 0.0048
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0097 0.0067 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0022 0.0135
Brugia malayi Protein kinase c protein 2 0.006 0.0035 0.0037
Brugia malayi hypothetical protein 0.0536 0.0448 0.0475
Trypanosoma cruzi cysteine proteinase, putative 0.103 0.0878 0.3055
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Echinococcus granulosus g-protein coupled receptor 0.0758 0.0641 0.1058
Echinococcus multilocularis raf serine:threonine protein kinase 0.1558 0.1337 0.2205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0001 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0006 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Echinococcus multilocularis 0.0028 0.0007 0.001
Schistosoma mansoni neuronal calcium sensor 0.0029 0.0008 0.0008
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0176 0.0136 0.0823
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1323 0.1132 0.3942
Schistosoma mansoni hypothetical protein 0.0047 0.0023 0.0023
Onchocerca volvulus 0.0093 0.0063 0.0383
Brugia malayi Transient-receptor-potential like protein 0.0042 0.0019 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0021 0.0021
Leishmania major hypothetical protein, conserved 0.0029 0.0008 0.0041
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0005 0.0047
Schistosoma mansoni memapsin-2 (A01 family) 0.042 0.0348 0.0348
Echinococcus multilocularis biogenic amine (5HT) receptor 0.3081 0.2661 0.4389
Mycobacterium ulcerans hypothetical protein 0.0035 0.0013 0.0255
Echinococcus granulosus Regulator of G protein signaling 20 0.0037 0.0015 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0758 0.0641 0.0679
Brugia malayi RhoGAP domain containing protein 0.0054 0.003 0.0031
Brugia malayi follicle stimulating hormone receptor 0.0981 0.0835 0.0885
Echinococcus granulosus FTZ F1 alpha 0.005 0.0026 0.0043
Entamoeba histolytica calcium-binding protein, putative 0.0029 0.0008 0.0048
Echinococcus granulosus calpain 0.0244 0.0195 0.0321
Echinococcus granulosus sodium and chloride dependent glycine 0.2752 0.2375 0.3918
Trichomonas vaginalis calcium binding protein, putative 0.0029 0.0008 0.0048
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Schistosoma mansoni cathepsin C 0.0426 0.0353 0.0353
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0003 0.0005
Echinococcus multilocularis unc 13 (munc13) 0.0054 0.003 0.0049
Onchocerca volvulus Putative nachr subunit 0.0063 0.0038 0.0228
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0244 0.0195 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.005 0.0026 0.0027
Echinococcus granulosus ecdysone induced protein 78C 0.005 0.0026 0.0043
Onchocerca volvulus 0.0758 0.0641 0.3893
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0007 0.0058
Giardia lamblia Alanyl dipeptidyl peptidase 0.0176 0.0136 0.1197
Schistosoma mansoni adenoreceptor 0.0758 0.0641 0.0641
Brugia malayi C1-like domain containing protein 0.006 0.0035 0.0037
Brugia malayi RNA, U transporter 1 0.0081 0.0053 0.0056
Echinococcus granulosus raf serine:threonine protein kinase 0.1558 0.1337 0.2205
Brugia malayi hypothetical protein 0.0064 0.0038 0.004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0758 0.0641 0.0641
Brugia malayi nuclear hormone receptor 0.005 0.0026 0.0027
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0004 0.0004
Brugia malayi cathepsin B-like cysteine proteinase 0.3325 0.2873 0.3043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0031 0.0184
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0074 0.0674
Echinococcus multilocularis G-protein coupled receptor, putative 0.0758 0.0641 0.1058
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0013 0.0255
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Brugia malayi ecdysteroid receptor 0.005 0.0026 0.0027
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Onchocerca volvulus 0.0758 0.0641 0.3893
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0244 0.0195 0.0677
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0021 0.0021
Onchocerca volvulus 0.0027 0.0006 0.0035
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0005 0.0032
Toxoplasma gondii hypothetical protein 0.0536 0.0448 0.272
Onchocerca volvulus 0.0758 0.0641 0.3893
Schistosoma mansoni unc-13 (munc13) 0.0057 0.0032 0.0032
Echinococcus multilocularis nibrin 0.0021 0.0001 0.0002
Brugia malayi diacylglycerol kinase 0.0054 0.003 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0007 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0008
Trypanosoma cruzi cruzipain precursor, putative 0.0603 0.0507 0.1765
Trypanosoma brucei trypanothione reductase 0.0046 0.0022 0.0125
Trypanosoma brucei I/6 autoantigen 0.0029 0.0008 0.0041
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0015 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.103 0.0878 0.5081
Echinococcus granulosus proteasome prosome macropain 0.0081 0.0053 0.0087
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.006 0.0035 0.0037
Trypanosoma brucei Calpain-like protein CALP1.3 0.0073 0.0046 0.0263
Trypanosoma cruzi oligopeptidase b 0.0592 0.0497 0.1731
Schistosoma mansoni biogenic amine receptor 0.0758 0.0641 0.0641
Leishmania major importin beta-1 subunit, putative 0.0023 0.0003 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0035 0.0013 0.0046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0086 0.1728
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0005 0.0031
Schistosoma mansoni neuronal calcium sensor 0.0029 0.0008 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0086 0.1728
Brugia malayi Cathepsin L-like precursor 0.1311 0.1123 0.1189
Schistosoma mansoni calpain-2 (C02 family) 0.0073 0.0046 0.0046
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0029 0.0031
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0015 0.0016
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0012 0.002
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0013 0.0014
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0029 0.0008 0.0027
Brugia malayi Cytochrome P450 family protein 0.0028 0.0007 0.0007
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0315 0.0257 0.0257
Echinococcus multilocularis sodium and chloride dependent glycine 0.2752 0.2375 0.3918
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0015 0.0016
Onchocerca volvulus 0.0063 0.0038 0.0228
Echinococcus granulosus survival motor neuron protein 1 0.0749 0.0634 0.1046
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0029 0.0048
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0054 0.003 0.003
Schistosoma mansoni microtubule-associated protein tau 0.1347 0.1153 0.1153
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0063 0.0038 0.004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0003 0.0003
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0536 0.0448 0.0739
Trypanosoma brucei mitochondrial calcium uptake 1 0.0029 0.0008 0.0041
Toxoplasma gondii cathepsin B 0.1323 0.1132 0.6875
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0426 0.0353 0.0374
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus granulosus biogenic amine 5HT receptor 0.5549 0.4806 0.7929
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0038 0.0062
Entamoeba histolytica cysteine proteinase 1, putative 0.103 0.0878 0.5329
Brugia malayi GPI-anchor transamidase 0.0034 0.0012 0.0013
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Echinococcus granulosus protein kinase c iota type 0.006 0.0035 0.0058
Brugia malayi hypothetical protein 0.0037 0.0015 0.0016
Brugia malayi PXA domain containing protein 0.0037 0.0015 0.0016
Echinococcus granulosus methyl CpG binding domain protein 2 0.0039 0.0016 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0005 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0758 0.0641 0.0641
Echinococcus granulosus neuropeptide receptor A26 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Echinococcus granulosus calcium uptake protein 1 0.0029 0.0008 0.0013
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0039 0.0017 0.0017
Plasmodium falciparum centrin-1 0.0029 0.0008 0.0047
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0376 0.031 0.031
Brugia malayi Cation transporter family protein 0.0063 0.0038 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Entamoeba histolytica hypothetical protein 0.0076 0.0049 0.0295
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0006 0.0006
Brugia malayi RhoGEF domain containing protein 0.0054 0.003 0.0031
Echinococcus granulosus somatostatin receptor 0.0758 0.0641 0.1058
Leishmania major cathepsin L-like protease 0.1915 0.1647 0.9538
Giardia lamblia GTOR 0.0035 0.0013 0.0117
Schistosoma mansoni hypothetical protein 0.0758 0.0641 0.0641
Brugia malayi Dopamine receptor protein 1 0.0758 0.0641 0.0679
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0006 0.012
Brugia malayi Serotonin receptor 0.0758 0.0641 0.0679
Echinococcus granulosus calpain 7 C02 family 0.0244 0.0195 0.0321
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Echinococcus multilocularis Transglutaminase 0.0034 0.0013 0.002
Brugia malayi hypothetical protein 0.0088 0.0059 0.0063
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0176 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0749 0.0634 0.0672
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0015 0.009
Echinococcus multilocularis allatostatin A receptor 0.0758 0.0641 0.1058
Entamoeba histolytica cysteine proteinase, putative 0.103 0.0878 0.5329
Onchocerca volvulus 0.1915 0.1647 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0012 0.0019
Onchocerca volvulus 0.1915 0.1647 1
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0035 0.0013 0.0073
Brugia malayi Tachykinin-like peptides receptor 99D 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0093 0.0064 0.0067
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0426 0.0353 0.2144
Leishmania major calmodulin, putative 0.0029 0.0008 0.0041
Onchocerca volvulus 0.0029 0.0008 0.0048
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0068 0.0072
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0003 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.103 0.0878 0.5329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0005 0.0005
Trichomonas vaginalis calmodulin-2, putative 0.0029 0.0008 0.0048
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.0329 0.0269 0.0269
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0007 0.0058
Echinococcus multilocularis protein kinase c epsilon type 0.006 0.0035 0.0058
Brugia malayi G-protein coupled receptor 0.0758 0.0641 0.0679
Plasmodium vivax glutathione reductase, putative 0.0046 0.0022 0.0135
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.005 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Brugia malayi hypothetical protein 0.0024 0.0004 0.0004
Echinococcus multilocularis protein dispatched 1 0.0152 0.0115 0.0189
Entamoeba histolytica hypothetical protein 0.0426 0.0353 0.2144
Plasmodium falciparum serine repeat antigen 7 0.0426 0.0353 0.2144
Trypanosoma brucei caltractin, putative 0.0029 0.0008 0.0041
Echinococcus granulosus single minded 2 0.0035 0.0013 0.0021
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Giardia lamblia Hypothetical protein 0.0029 0.0008 0.007
Schistosoma mansoni RAR-like nuclear receptor 0.005 0.0026 0.0026
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0112 0.008 0.046
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0026 0.0043
Echinococcus multilocularis calpain 0.0244 0.0195 0.0321
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0015 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0063 0.0038 0.0062
Schistosoma mansoni transient receptor potential channel 0.007 0.0043 0.0043
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0012 0.0012
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0007 0.0126
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0029 0.0008 0.0013
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0006 0.0055
Toxoplasma gondii hypothetical protein 0.0176 0.0136 0.0823
Onchocerca volvulus 0.0758 0.0641 0.3893
Schistosoma mansoni mitochondrial solute carrier 0.0029 0.0008 0.0008
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0376 0.031 0.0511
Onchocerca volvulus 0.0758 0.0641 0.3893
Onchocerca volvulus Cathepsin L homolog 0.1915 0.1647 1
Leishmania major centrin, putative 0.0029 0.0008 0.0041
Schistosoma mansoni thyroid hormone receptor 0.005 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0006 0.012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0008
Echinococcus granulosus transient receptor potential ion channel A 0.0091 0.0062 0.0102
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.016 0.0122 0.1116
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0008
Schistosoma mansoni pyruvate kinase 0.0037 0.0015 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0068 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Trypanosoma brucei ISWI complex protein 0.0035 0.0013 0.0069
Brugia malayi diacylglycerol kinase 0.0054 0.003 0.0031
Mycobacterium leprae Conserved hypothetical protein 0.0034 0.0013 0.0228
Brugia malayi hypothetical protein 0.0026 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Brugia malayi topoisomerase 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Onchocerca volvulus 0.1915 0.1647 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0758 0.0641 0.0679
Giardia lamblia Proteasome subunit beta type 2 0.0039 0.0016 0.0144
Leishmania major hypothetical protein, conserved 0.0185 0.0143 0.0825
Echinococcus granulosus dro:myosuppressin receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis esterase, putative 0.0035 0.0013 0.0078
Brugia malayi cathepsin L-like cysteine proteinase 0.0426 0.0353 0.0374
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0029 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0021 0.0021
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.272
Mycobacterium ulcerans putative transglutaminase-like protein 0.0034 0.0013 0.0247
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Echinococcus granulosus importin subunit beta 1 0.0029 0.0008 0.0012
Echinococcus multilocularis calpain 5 0.0244 0.0195 0.0321
Echinococcus multilocularis microtubule associated protein 2 0.1347 0.1153 0.1903
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0135 0.01 0.0165
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0006 0.0006
Plasmodium falciparum calpain 0.0073 0.0046 0.028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0013 0.0117
Loa Loa (eye worm) hypothetical protein 0.0603 0.0507 0.0537
Giardia lamblia Pyruvate kinase 0.0037 0.0015 0.0132
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.0086 0.0142
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0029 0.0008 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0014 0.0075
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Plasmodium vivax proteasome subunit beta type-2, putative 0.0039 0.0016 0.0098
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0426 0.0353 0.3119
Trypanosoma brucei C-8 sterol isomerase, putative 0.0357 0.0293 0.1693
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0001 0.0013
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0014 0.0022
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.0064 0.0067
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0005 0.0031
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Echinococcus granulosus pyruvate kinase 0.0037 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.005 0.0026 0.0043
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0264 0.0212 0.1226
Brugia malayi hypothetical protein 0.0026 0.0006 0.0006
Plasmodium vivax proteasome subunit beta type-1, putative 0.0063 0.0037 0.0224
Mycobacterium tuberculosis Conserved protein 0.0034 0.0013 0.0113
Echinococcus granulosus orexin receptor type 2 0.0758 0.0641 0.1058
Brugia malayi hypothetical protein 0.0749 0.0634 0.0672
Brugia malayi Nuclear hormone receptor family member nhr-3 0.005 0.0026 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0013 0.0044
Plasmodium falciparum pyruvate kinase 0.0037 0.0015 0.009
Echinococcus multilocularis survival motor neuron protein 1 0.0749 0.0634 0.1046
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0013 0.0021
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0647 0.0545 0.0545
Entamoeba histolytica grainin, putative 0.0029 0.0008 0.0048
Schistosoma mansoni hypothetical protein 0.0758 0.0641 0.0641
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0509 0.0425 0.0701
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0476 0.0397 0.042
Echinococcus multilocularis programmed cell death protein 0.0029 0.0008 0.0013
Schistosoma mansoni nAChR subunit 0.0024 0.0004 0.0004
Trypanosoma brucei protein I/6 0.0029 0.0008 0.0041
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0001 0.0004
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0084 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) hypothetical protein 0.0176 0.0136 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0007
Echinococcus granulosus neuropeptide receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3325 0.2873 0.2873
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0029 0.0008 0.0048
Entamoeba histolytica grainin 2 0.0029 0.0008 0.0048
Loa Loa (eye worm) hypothetical protein 0.0033 0.0012 0.0012
Plasmodium falciparum cysteine proteinase falcipain 1 0.103 0.0878 0.5329
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.0353 0.0353
Schistosoma mansoni methyl-cpg binding protein mbd 0.0039 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.005 0.0026 0.0027
Plasmodium falciparum serine repeat antigen 9 0.0426 0.0353 0.2144
Entamoeba histolytica prolyl oligopeptidase family protein 0.0176 0.0136 0.0823
Giardia lamblia Fructose-bisphosphate aldolase 0.0327 0.0267 0.2358
Trypanosoma brucei calpain-like protein, putative 0.0244 0.0195 0.1123
Entamoeba histolytica hypothetical protein 0.0037 0.0015 0.0091
Schistosoma mansoni methyl-cpg binding protein mbd 0.0039 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.0136 0.0472
Loa Loa (eye worm) hypothetical protein 1.0878 0.9439 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0014 0.0047
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0215 0.0169 0.0279
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0038 0.004
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0038 0.0062
Schistosoma mansoni neuropeptide receptor 0.0758 0.0641 0.0641
Loa Loa (eye worm) PXA domain-containing protein 0.0037 0.0015 0.0016
Echinococcus multilocularis sex peptide receptor 0.0758 0.0641 0.1058
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0426 0.0353 0.0353
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426 0.0353 0.3119
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0215 0.0169 0.0279
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0426 0.0353 0.2144
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Leishmania major hypothetical protein, unknown function 0.0073 0.0046 0.0263
Echinococcus multilocularis mitogen activated protein kinase 14 0.1175 0.1004 0.1657
Mycobacterium ulcerans hypothetical protein 0.0034 0.0013 0.0247
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0647 0.0545 0.0577
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0676 0.057 0.057
Giardia lamblia Cathepsin L-like protease 0.0426 0.0353 0.3119
Loa Loa (eye worm) hypothetical protein 0.0092 0.0063 0.0066
Plasmodium falciparum serine repeat antigen 3 0.0426 0.0353 0.2144
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0006 0.0037
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0035 0.0013 0.0022
Giardia lamblia GPI-anchor transamidase, putative 0.0034 0.0012 0.0106
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0426 0.0353 0.2144
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0244 0.0195 0.1123
Trypanosoma brucei calpain-like protein, putative 0.0244 0.0195 0.1123
Trichomonas vaginalis set domain proteins, putative 0.0737 0.0623 0.3781
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.0027 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Echinococcus granulosus microtubule associated protein 2 0.1347 0.1153 0.1903
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0022 0.0037
Loa Loa (eye worm) glutaminase 2 0.026 0.0209 0.0221
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0049 0.008
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0013 0.0078
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis neuropeptide FF receptor 2 0.0758 0.0641 0.1058
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Leishmania major C-8 sterol isomerase-like protein 0.0357 0.0293 0.1693
Loa Loa (eye worm) hypothetical protein 0.0163 0.0124 0.0132
Schistosoma mansoni unc-13 (munc13) 0.0054 0.003 0.003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0001 0.0001
Trichomonas vaginalis hypothetical protein 0.0073 0.0046 0.028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0004 0.0004
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0008 0.0048
Toxoplasma gondii calmodulin CAM1 0.0029 0.0008 0.0048
Brugia malayi Cytochrome P450 family protein 0.0053 0.0029 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Echinococcus multilocularis serotonin receptor 0.5549 0.4806 0.7929
Brugia malayi hypothetical protein 0.0024 0.0004 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0647 0.0545 0.0577
Echinococcus multilocularis short transient receptor potential channel 6 0.007 0.0043 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0008 0.0048
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0013 0.008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.0677
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0592 0.0497 0.1731
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0007 0.0126
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0006 0.012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0014 0.0083
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3325 0.2873 0.2873
Echinococcus granulosus Rac GTPase activating protein 1 0.0054 0.003 0.0049
Onchocerca volvulus 0.1915 0.1647 1
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0012 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0603 0.0507 0.1765
Brugia malayi G-protein coupled receptor 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Toxoplasma gondii hypothetical protein 0.0536 0.0448 0.272
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0013 0.0014
Brugia malayi calpain 5 0.0171 0.0131 0.0139
Entamoeba histolytica calpain family cysteine protease, putative 0.0073 0.0046 0.028
Brugia malayi Papain family cysteine protease containing protein 0.0426 0.0353 0.0374
Toxoplasma gondii EFHC1, putative 0.0029 0.0008 0.0048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.0475
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0035 0.0013 0.0046
Schistosoma mansoni thyroid hormone receptor 0.005 0.0026 0.0026
Entamoeba histolytica cysteine proteinase 2 0.103 0.0878 0.5329
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0068 0.0072
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0005
Echinococcus granulosus calbindin 32 0.0029 0.0008 0.0013
Giardia lamblia Cysteine protease 0.0426 0.0353 0.3119
Brugia malayi ecdysone receptor 0.0024 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0132 0.0097 0.016
Leishmania major cathepsin L-like protease 0.2007 0.1727 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0518 0.0433 0.1507
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0758 0.0641 0.1058
Brugia malayi proteasome subunit beta type 1 0.0063 0.0037 0.0039
Echinococcus multilocularis sodium channel protein 0.0112 0.008 0.0132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3325 0.2873 0.2873
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0007 0.0126
Schistosoma mansoni calpain-7 (C02 family) 0.0247 0.0197 0.0197
Trichomonas vaginalis calcineurin B subunit, putative 0.0029 0.0008 0.0048
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.006 0.0035 0.0058
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1448 0.1241 0.7185
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0007 0.0126
Echinococcus multilocularis geminin 0.0355 0.0292 0.0481
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0001 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0083 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2438 0.2102 0.3468
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1915 0.1647 0.2717
Onchocerca volvulus 0.0536 0.0448 0.272
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.005 0.0026 0.0027
Mycobacterium tuberculosis Long conserved protein 0.0034 0.0013 0.0113
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0758 0.0641 0.1058
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Plasmodium vivax vivapain-2 0.1915 0.1647 1
Echinococcus granulosus unc 13 munc13 0.0054 0.003 0.0049
Leishmania major cathepsin L-like protease 0.1915 0.1647 0.9538
Leishmania major cathepsin L-like protease 0.2007 0.1727 1
Loa Loa (eye worm) hypothetical protein 0.0603 0.0507 0.0537
Brugia malayi hypoxia-induced factor 1 0.0146 0.011 0.0116
Echinococcus multilocularis nAChR subunit 0.0039 0.0017 0.0027
Schistosoma mansoni calmodulin 0.0029 0.0008 0.0008
Schistosoma mansoni calmodulin 0.0029 0.0008 0.0008
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0001 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1915 0.1647 0.1745
Schistosoma mansoni lipoxygenase 0.008 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0003 0.0005
Loa Loa (eye worm) MBCTL1 0.0061 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0001 0.0003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0031 0.0106
Brugia malayi Cathepsin L-like cysteine proteinase 0.1311 0.1123 0.1189
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0003 0.0016
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0054 0.003 0.0031
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.0177 0.1621
Echinococcus multilocularis orexin receptor type 2 0.0758 0.0641 0.1058
Echinococcus multilocularis vesicular acetylcholine transporter 0.0214 0.0169 0.0279
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0038 0.004
Echinococcus granulosus histone lysine methyltransferase setb 0.0132 0.0097 0.016
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0003 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0029 0.003
Schistosoma mansoni opsin-like receptor 0.0758 0.0641 0.0641
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0031 0.0184
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.1123
Onchocerca volvulus 0.1915 0.1647 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0038 0.004
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.031 0.0252 0.1532
Loa Loa (eye worm) beta-lactamase 0.0035 0.0013 0.0014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0536 0.0448 0.0739
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0758 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Onchocerca volvulus 0.0758 0.0641 0.3893
Brugia malayi protein kinase C II. 0.006 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Schistosoma mansoni zinc finger protein 0.0024 0.0003 0.0003
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0426 0.0353 0.0353
Loa Loa (eye worm) LGC-31 protein 0.0063 0.0038 0.004
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0004 0.0004
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0426 0.0353 0.2144
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0038 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0007
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0063 0.0038 0.0038
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0007 0.0126
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0021 0.0021
Brugia malayi Thioredoxin reductase 0.0046 0.0022 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0015 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0758 0.0641 0.0679
Schistosoma mansoni patched 1 0.0133 0.0098 0.0098
Entamoeba histolytica hypothetical protein 0.0039 0.0017 0.01
Mycobacterium leprae Probable lipase LipE 0.0035 0.0013 0.0236
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0001 0.0007
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.272
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Brugia malayi hypothetical protein 0.0024 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0054 0.003 0.018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.005 0.0026 0.0157
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Onchocerca volvulus 0.0758 0.0641 0.3893
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Schistosoma mansoni hypothetical protein 0.0066 0.004 0.004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0007 0.0022
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0647 0.0545 0.0577
Echinococcus multilocularis dro:myosuppressin receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0013 0.0078
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0012 0.0012
Echinococcus multilocularis snurportin 1 0.0306 0.0249 0.041
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1915 0.1647 0.1745
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.0064 0.0105
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0074 0.0674
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0004 0.0006
Trypanosoma cruzi centrin, putative 0.0029 0.0008 0.0027
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0007 0.0022
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0063 0.0037 0.0061
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Toxoplasma gondii proteasome subunit beta type, putative 0.0081 0.0053 0.032
Echinococcus multilocularis ecdysone induced protein 78C 0.005 0.0026 0.0043
Echinococcus multilocularis expressed conserved protein 0.0292 0.0236 0.0389
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0004 0.0006
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0007 0.0058
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0029 0.0008 0.0013
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0081 0.0053 0.032
Loa Loa (eye worm) proteasome subunit beta type 2 0.0039 0.0016 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0006 0.0006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0018
Giardia lamblia Hypothetical protein 0.0034 0.0013 0.0109
Echinococcus granulosus nAChR subunit 0.0063 0.0038 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1403 0.1202 0.4185
Toxoplasma gondii troponin c, isotype gamma, putative 0.0029 0.0008 0.0048
Mycobacterium ulcerans lipase LipD 0.0035 0.0013 0.0255
Chlamydia trachomatis pyruvate kinase 0.0037 0.0015 0.0331
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0264 0.0212 0.1289
Loa Loa (eye worm) hypothetical protein 1.0878 0.9439 1
Onchocerca volvulus Protein ultraspiracle homolog 0.005 0.0026 0.0157
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0426 0.0353 0.2144
Echinococcus granulosus expressed conserved protein 0.0292 0.0236 0.0389
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0063 0.0038 0.004
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0001 0.001
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0063 0.0038 0.0062
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0029 0.0008 0.0048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.0027 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0038 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Plasmodium falciparum transporter, putative 0.0536 0.0448 0.272
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0426 0.0353 0.2144
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0054 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Echinococcus granulosus Protein patched homolog 1 0.0133 0.0098 0.0162
Trypanosoma brucei Component of motile flagella 41 0.0029 0.0008 0.0041
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0021 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0026 0.0043
Schistosoma mansoni lamin 0.0027 0.0006 0.0006
Echinococcus granulosus EF HAND 1 calcium binding site 0.0029 0.0008 0.0013
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426 0.0353 0.3119
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426 0.0353 0.3119
Schistosoma mansoni calpain (C02 family) 0.0244 0.0195 0.0195
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0073 0.0046 0.0263
Onchocerca volvulus 0.0758 0.0641 0.3893
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0007 0.0126
Echinococcus multilocularis pyruvate kinase 0.0037 0.0015 0.0025
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0536 0.0448 0.0739
Schistosoma mansoni neuropeptide receptor 0.0758 0.0641 0.0641
Entamoeba histolytica prolyl oligopeptidase family protein 0.0176 0.0136 0.0823
Plasmodium falciparum peptidase, putative 0.0176 0.0136 0.0823
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0007 0.0126
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0004 0.0006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0037 0.0015 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0013 0.0013
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0015 0.0015
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0002 0.0006
Echinococcus granulosus sodium channel protein 0.0112 0.008 0.0132
Leishmania major calcineurin B subunit, putative 0.0029 0.0008 0.0041
Echinococcus granulosus sterol regulatory element binding protein 0.0133 0.0098 0.0162
Trypanosoma cruzi centrin-3 0.0029 0.0008 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0426 0.0353 0.2144
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.005 0.0026 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0031 0.0184
Echinococcus multilocularis g protein coupled receptor 0.0758 0.0641 0.1058
Echinococcus granulosus histone acetyltransferase MYST2 0.0061 0.0035 0.0058
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0022 0.0204
Schistosoma mansoni hypothetical protein 0.0128 0.0094 0.0094
Schistosoma mansoni biogenic amine receptor 0.0758 0.0641 0.0641
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0035 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0158 0.012 0.0127
Echinococcus multilocularis cathepsin L cysteine protease 0.1915 0.1647 0.2717
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Schistosoma mansoni hypothetical protein 0.0072 0.0045 0.0045
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0005 0.0026
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase 11 0.1175 0.1004 0.1657
Brugia malayi Proteasome A-type and B-type family protein 0.0081 0.0053 0.0056
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0006 0.01
Echinococcus granulosus neuropeptide Y receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0042 0.0019 0.0031
Entamoeba histolytica hypothetical protein 0.0076 0.0049 0.0295
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Entamoeba histolytica prolyl oligopeptidase family protein 0.0176 0.0136 0.0823
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0536 0.0448 0.0739
Schistosoma mansoni sodium-dependent amino acid transporter 0.0536 0.0448 0.0448
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0013 0.0078
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0041 0.0043
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0054 0.003 0.0049
Leishmania major hypothetical protein, conserved 0.0035 0.0013 0.007
Echinococcus multilocularis neuropeptide Y receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) glutathione reductase 0.0046 0.0022 0.0024
Brugia malayi putative neuropeptide receptor NPR1 0.0758 0.0641 0.0679
Giardia lamblia Hypothetical protein 0.0426 0.0353 0.3119
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2557 0.2205 0.3638
Schistosoma mansoni neurotransmitter gated ion channel 0.0039 0.0017 0.0017
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0063 0.0038 0.0038
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0015 0.0025
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0063 0.0038 0.004
Brugia malayi hypothetical protein 0.0147 0.0111 0.0117
Toxoplasma gondii centrin, putative 0.0029 0.0008 0.0048
Echinococcus multilocularis musashi 0.0027 0.0006 0.0009
Entamoeba histolytica cysteine protease, putative 0.1915 0.1647 1
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0098 0.0596
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.0353 0.0353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0029 0.0008 0.0008
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0017 0.0017
Loa Loa (eye worm) cytochrome P450 0.0028 0.0007 0.0007
Schistosoma mansoni neuropeptide receptor 0.0758 0.0641 0.0641
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0063 0.0038 0.0038
Toxoplasma gondii hypothetical protein 0.0073 0.0046 0.028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0013 0.0113
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1175 0.1004 0.3496
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0029 0.0048
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0176 0.0136 0.0823
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0013 0.0072
Schistosoma mansoni amine GPCR 0.0758 0.0641 0.0641
Giardia lamblia Cysteine protease 0.0426 0.0353 0.3119
Echinococcus granulosus retinoic acid receptor rxr beta a 0.005 0.0026 0.0043
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0176 0.0136 0.0823
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0107 0.0076 0.0124
Echinococcus granulosus short transient receptor potential channel 6 0.0069 0.0043 0.007
Brugia malayi nuclear receptor NHR-67 0.0024 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0758 0.0641 0.1058
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0003 0.0005
Schistosoma mansoni neuropeptide F-like receptor 0.0758 0.0641 0.0641
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0038 0.0062
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Brugia malayi intermediate filament protein 0.0027 0.0006 0.0006
Echinococcus granulosus cathepsin b 0.3325 0.2873 0.4739
Giardia lamblia Alanyl dipeptidyl peptidase 0.0176 0.0136 0.1197
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0046 0.028
Schistosoma mansoni centrin 0.0029 0.0008 0.0008
Mycobacterium tuberculosis Hypothetical protein 0.0034 0.0013 0.0113
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Brugia malayi putative neuropeptide receptor 0.0758 0.0641 0.0679
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.005 0.0026 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0007 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Onchocerca volvulus 0.005 0.0026 0.0157
Plasmodium falciparum importin beta, putative 0.0029 0.0008 0.0044
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Giardia lamblia Proteasome subunit beta type 1 0.0063 0.0037 0.0327
Echinococcus multilocularis Niemann Pick C1 protein 0.0444 0.0368 0.0607
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Schistosoma mansoni hypothetical protein 0.0128 0.0094 0.0094
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0376 0.031 0.0511
Echinococcus multilocularis neurocalcin 0.0029 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0 0.000009889
Onchocerca volvulus 0.1311 0.1123 0.6815
Brugia malayi Cathepsin L-like precursor 0.1311 0.1123 0.1189
Echinococcus granulosus 7TM GPCR rhodopsin 0.0758 0.0641 0.1058
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0426 0.0353 0.2144
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0008 0.0038
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0063 0.0038 0.004
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0006 0.0009
Trypanosoma cruzi prolyl endopeptidase 0.1448 0.1241 0.432
Schistosoma mansoni hypothetical protein 0.0034 0.0013 0.0013
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0038 0.0062
Plasmodium vivax unspecified product 0.0426 0.0353 0.2144
Loa Loa (eye worm) fibroinase 0.1915 0.1647 0.1745
Schistosoma mansoni neuropeptide F-like receptor 0.0758 0.0641 0.0641
Brugia malayi prolyl oligopeptidase family protein 0.0176 0.0136 0.0144
Mycobacterium leprae putative cytochrome p450 0.0028 0.0007 0.0106
Trypanosoma brucei calpain-like protein, putative 0.0244 0.0195 0.1123
Echinococcus granulosus g protein coupled receptor 0.0758 0.0641 0.1058
Brugia malayi Niemann-Pick C1 protein precursor 0.031 0.0252 0.0267
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0004 0.0004
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0034 0.0012 0.0065
Schistosoma mansoni hypothetical protein 0.0758 0.0641 0.0641
Leishmania major cytochrome p450-like protein 0.0028 0.0007 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Leishmania major trypanothione reductase 0.0046 0.0022 0.0125
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0005 0.0031
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0007 0.0033
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0426 0.0353 0.2144
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.011 0.011
Echinococcus multilocularis neuropeptide receptor A26 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Brugia malayi ORL1-like opioid receptor 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0007 0.0058
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0015 0.0025
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0015 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Brugia malayi cytochrome P450 0.0028 0.0007 0.0007
Echinococcus multilocularis hypothetical protein 0.0244 0.0195 0.0321
Brugia malayi nuclear receptor NHR-88 0.0024 0.0003 0.0003
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0054 0.003 0.0049
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1175 0.1004 0.1064
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0592 0.0497 0.2876
Loa Loa (eye worm) programmed cell death protein 6 0.0029 0.0008 0.0008
Onchocerca volvulus 0.0063 0.0038 0.0228
Loa Loa (eye worm) steroid hormone receptor 0.005 0.0026 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0063 0.0063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1915 0.1647 0.2717
Schistosoma mansoni topbp1 0.0021 0.0001 0.0001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0013 0.007
Loa Loa (eye worm) hypothetical protein 0.002 0 0.000009889
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0003 0.0003
Giardia lamblia Encystation-specific protease 0.0426 0.0353 0.3119
Onchocerca volvulus 0.0536 0.0448 0.272
Brugia malayi G protein-coupled receptor 0.0758 0.0641 0.0679
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0054 0.003 0.0031
Plasmodium vivax GPI-anchor transamidase, putative 0.0034 0.0012 0.0072
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0015 0.0015
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0063 0.0037 0.0224
Entamoeba histolytica hypothetical protein 0.0037 0.0015 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0026 0.0027
Echinococcus granulosus tachykinin peptides receptor 99D 0.0758 0.0641 0.1058
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.016 0.0122 0.2427
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Loa Loa (eye worm) GABA receptor subunit 0.0039 0.0017 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Echinococcus granulosus prolyl endopeptidase 0.1448 0.1241 0.2047
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0004 0.0004
Toxoplasma gondii peptidase c13 family protein 0.0034 0.0012 0.0073
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0676 0.057 0.0941
Leishmania major pyruvate kinase 0.0037 0.0015 0.0082
Onchocerca volvulus 0.0063 0.0038 0.0228
Echinococcus multilocularis neuropeptide receptor 0.0758 0.0641 0.1058
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0037 0.0015 0.0025
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0001 0.0006
Trypanosoma brucei prolyl oligopeptidase, putative 0.0592 0.0497 0.2876
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0029 0.0008 0.0041
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 1.0878 0.9439 0.9439
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0049 0.008
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0008 0.0041
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0063 0.0038 0.004
Echinococcus granulosus lamin dm0 0.0027 0.0006 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus granulosus serotonin receptor 0.0758 0.0641 0.1058
Entamoeba histolytica hypothetical protein 0.0026 0.0005 0.0032
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0176 0.0136 0.0823
Brugia malayi Nuclear hormone receptor family member nhr-1 0.005 0.0026 0.0027
Brugia malayi glutathione reductase 0.0046 0.0022 0.0024
Chlamydia trachomatis DNA ligase 0.0021 0.0001 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0 0.000009889
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0003 0.0005
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0492 0.0411 0.0411
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0011 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0758 0.0641 0.0641
Onchocerca volvulus 0.0758 0.0641 0.3893
Schistosoma mansoni Tr4/Tr2 (homologue) 0.005 0.0026 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0004 0.0004
Echinococcus granulosus neurocalcin 0.0029 0.0008 0.0013
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0001 0.0002
Onchocerca volvulus Cathepsin L homolog 0.0426 0.0353 0.2144
Schistosoma mansoni coup transcription factor 0.005 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0002 0.0011
Schistosoma mansoni histamine h1 receptor 0.0758 0.0641 0.0641
Onchocerca volvulus Bile acid receptor homolog 0.005 0.0026 0.0157
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0038 0.004
Schistosoma mansoni hypothetical protein 0.0033 0.0012 0.0012
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1175 0.1004 0.5813
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.0475
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0004 0.0004
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0357 0.0293 0.031
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Onchocerca volvulus 0.0536 0.0448 0.272
Trichomonas vaginalis conserved hypothetical protein 0.0426 0.0353 0.2144
Leishmania major cathepsin L-like protease 0.1915 0.1647 0.9538
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0039 0.0016 0.0026
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0492 0.0411 0.2492
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Brugia malayi Kringle domain containing protein 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0024 0.0004 0.0022
Trypanosoma cruzi ISWI complex protein 0.0035 0.0013 0.0044
Echinococcus multilocularis serotonin receptor 0.5549 0.4806 0.7929
Schistosoma mansoni hypothetical protein 0.0128 0.0094 0.0094
Brugia malayi AKH receptor 0.0758 0.0641 0.0679
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.103 0.0878 0.5329
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-31 0.005 0.0026 0.0027
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0007 0.0126
Onchocerca volvulus Alhambra homolog 0.0033 0.0011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0133 0.0098 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Mycobacterium ulcerans hypothetical protein 0.0034 0.0013 0.0247
Trichomonas vaginalis calpain, putative 0.0073 0.0046 0.028
Schistosoma mansoni DNA ligase IV 0.0021 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0001 0.0005
Echinococcus multilocularis calumenin 0.0029 0.0008 0.0013
Echinococcus multilocularis EF hand domain containing family member A2 0.0029 0.0008 0.0013
Trypanosoma brucei protein kinase, putative 0.0055 0.0031 0.0172
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0244 0.0195 0.0677
Loa Loa (eye worm) hypothetical protein 0.2752 0.2375 0.2516
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0006 0.0006
Echinococcus multilocularis protein kinase c eta type 0.0054 0.003 0.0049
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.005 0.0026 0.0026
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Brugia malayi hypothetical protein 0.0037 0.0015 0.0016
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0063 0.0037 0.0129
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0426 0.0353 0.2144
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0758 0.0641 0.0679
Schistosoma mansoni hypothetical protein 0.0355 0.0292 0.0292
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0014 0.0022
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0244 0.0195 0.0677
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Brugia malayi Papain family cysteine protease containing protein 0.103 0.0878 0.093
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0015 0.0082
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0426 0.0353 0.0374
Onchocerca volvulus 0.0758 0.0641 0.3893
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0007 0.0126
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0035 0.0013 0.0013
Brugia malayi RE15519p 0.0758 0.0641 0.0679
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0082 0.0053 0.0088
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0006 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Echinococcus multilocularis proteasome (prosome, macropain) 0.0081 0.0053 0.0087
Plasmodium falciparum thioredoxin reductase 0.0046 0.0022 0.0135
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0007 0.0126
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0035 0.0013 0.0013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0014 0.0014
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0426 0.0353 0.0353
Schistosoma mansoni myelin transcription factor 1 myt1 0.0061 0.0035 0.0035
Trichomonas vaginalis calcium binding protein, putative 0.0029 0.0008 0.0048
Loa Loa (eye worm) calpain family protein 1 0.0647 0.0545 0.0577
Schistosoma mansoni amine GPCR 0.0758 0.0641 0.0641
Loa Loa (eye worm) calpain family protein 1 0.0476 0.0397 0.042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0758 0.0641 0.0679
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0035 0.0013 0.0072
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0758 0.0641 0.0679
Trichomonas vaginalis myosin light chain 1, putative 0.0029 0.0008 0.0048
Schistosoma mansoni protein kinase C 0.0054 0.003 0.003
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0001 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0536 0.0448 0.0739
Echinococcus multilocularis cathepsin L 0.0426 0.0353 0.0583
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Echinococcus granulosus Niemann Pick C1 protein 0.031 0.0252 0.0416
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0003 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0018
Trypanosoma brucei calpain, putative 0.0073 0.0046 0.0263
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0007 0.0033
Giardia lamblia Cathepsin B precursor 0.0426 0.0353 0.3119
Brugia malayi Papain family cysteine protease containing protein 0.0426 0.0353 0.0374
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus calpain 5 0.0244 0.0195 0.0321
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Probable reductase 0.0105 0.0074 0.0674
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0021 0.0034
Schistosoma mansoni ef hand domain family member A2 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0758 0.0641 0.1058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0012 0.0073
Leishmania major calpain family cysteine protease-like protein 0.0073 0.0046 0.0263
Giardia lamblia Cathepsin B precursor 0.0426 0.0353 0.3119
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0007 0.0126
Brugia malayi vesicular acetylcholine transporter unc-17 0.0214 0.0169 0.0179
Echinococcus granulosus biogenic amine 5HT receptor 0.3081 0.2661 0.4389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Echinococcus granulosus calumenin 0.0029 0.0008 0.0013
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0063 0.0037 0.0037
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Onchocerca volvulus 0.0536 0.0448 0.272
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor 0.005 0.0026 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0426 0.0353 0.2144
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0037 0.0015 0.0091
Schistosoma mansoni single-minded 0.0047 0.0024 0.0024
Brugia malayi beta-lactamase 0.0035 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Schistosoma mansoni growth hormone secretagogue receptor 0.0758 0.0641 0.0641
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0011 0.0065
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0008 0.0044
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0758 0.0641 0.0641
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0035 0.0013 0.008
Brugia malayi beta-lactamase family protein 0.0035 0.0013 0.0014
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0264 0.0212 0.0739
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0758 0.0641 0.1058
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0034 0.0036
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Schistosoma mansoni ran 0.0021 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.0053 0.0029 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0021 0.0021
Entamoeba histolytica Ran family GTPase 0.0021 0.0001 0.0005
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0015 0.0015
Echinococcus granulosus programmed cell death protein 0.0029 0.0008 0.0013
Brugia malayi PXA domain containing protein 0.0037 0.0015 0.0016
Echinococcus multilocularis histone acetyltransferase MYST2 0.0061 0.0035 0.0058
Brugia malayi nuclear hormone receptor 0.0024 0.0003 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0981 0.0835 0.0885
Trypanosoma cruzi cysteine peptidase, putative 0.1915 0.1647 0.5734
Schistosoma mansoni cathepsin B (C01 family) 0.0426 0.0353 0.0353
Echinococcus granulosus neuropeptides capa receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0063 0.0038 0.004
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0007 0.0058
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0014 0.012
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0035 0.0013 0.0072
Onchocerca volvulus 0.0035 0.0013 0.0078
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0264 0.0212 0.1226
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0007 0.0058
Schistosoma mansoni importin beta-1 0.0029 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0013 0.0072
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Loa Loa (eye worm) hypothetical protein 0.5549 0.4806 0.5092
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0013 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0013 0.0014
Schistosoma mansoni amine GPCR 0.0758 0.0641 0.0641
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0005 0.0082
Echinococcus granulosus cathepsin l cysteine peptidase 0.1915 0.1647 0.2717
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus centrin 2 0.0029 0.0008 0.0013
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0001 0.0003
Trypanosoma brucei cysteine peptidase C (CPC) 0.1323 0.1132 0.6556
Onchocerca volvulus 0.0153 0.0115 0.07
Onchocerca volvulus 0.0027 0.0006 0.0037
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0007 0.0058
Echinococcus granulosus Diacylglycerol kinase theta 0.0054 0.003 0.0049
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0031 0.0184
Loa Loa (eye worm) hypoxia-induced factor 1 0.0146 0.011 0.0116
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1915 0.1647 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0003 0.0016
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0063 0.0038 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0014 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.1558 0.1337 0.1337
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0536 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Trypanosoma brucei centrin, putative 0.0029 0.0008 0.0041
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0024 0.0024
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1311 0.1123 0.6815
Brugia malayi regulator of G-protein signaling rgs-7 0.0037 0.0015 0.0016
Brugia malayi cathepsin F-like cysteine proteinase 0.0426 0.0353 0.0374
Echinococcus multilocularis programmed cell death protein 0.0029 0.0008 0.0013
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0074 0.0674
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0536 0.0448 0.0739
Onchocerca volvulus 0.0039 0.0017 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Toxoplasma gondii centrin 0.0029 0.0008 0.0048
Echinococcus granulosus zinc finger protein 0.0044 0.0021 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0001 0.0007
Schistosoma mansoni lamin 0.0027 0.0006 0.0006
Plasmodium vivax unspecified product 0.103 0.0878 0.5329
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0074 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0758 0.0641 0.1058
Brugia malayi P38 map kinase family protein 2 0.1175 0.1004 0.1064
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0007 0.0058
Onchocerca volvulus 0.0054 0.003 0.018
Onchocerca volvulus 0.0021 0.0001 0.0006
Giardia lamblia Hypothetical protein 0.0426 0.0353 0.3119
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0426 0.0353 0.2144
Echinococcus multilocularis N chimaerin 0.0054 0.003 0.0049
Onchocerca volvulus 0.0024 0.0004 0.0022
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0001 0.0825
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Leishmania major proteasome beta 5 subunit, putative 0.0081 0.0053 0.0301
Schistosoma mansoni amine GPCR 0.0758 0.0641 0.0641
Echinococcus granulosus cathepsin L 0.103 0.0878 0.1448
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.0064 0.0064
Leishmania major programmed cell death 6 protein-like protein 0.0029 0.0008 0.0041
Leishmania major cathepsin L-like protease 0.2007 0.1727 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.0027 0.0027
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0758 0.0641 0.0679
Echinococcus multilocularis nAChR subunit 0.0063 0.0038 0.0062
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0022 0.0002 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0068 0.0112
Loa Loa (eye worm) hypothetical protein 0.016 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.1196 0.1023 0.1083
Schistosoma mansoni sodium/chloride dependent transporter 0.2752 0.2375 0.2375
Onchocerca volvulus 0.0024 0.0003 0.0018
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0176 0.0136 0.0781
Brugia malayi hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni glutaminase 0.026 0.0209 0.0209
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Schistosoma mansoni jun-related protein 0.0066 0.004 0.004
Plasmodium vivax SET domain protein, putative 0.0093 0.0063 0.0383
Schistosoma mansoni cytochrome P450 0.0028 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0003 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.103 0.0878 0.5081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0097 0.0097
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Trypanosoma brucei Calpain-like protein 1.1 0.0073 0.0046 0.0263
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.1196 0.1023 0.1083
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0006 0.0031
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0758 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trypanosoma cruzi cysteine protease, putative 0.103 0.0878 0.3055
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0063 0.0038 0.004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Echinococcus granulosus pyruvate kinase 0.0037 0.0015 0.0025
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0676 0.057 0.0941
Echinococcus granulosus fmrfamide receptor 0.0758 0.0641 0.1058
Plasmodium falciparum proteasome subunit beta type-5 0.0081 0.0053 0.032
Echinococcus multilocularis protein kinase c iota type 0.006 0.0035 0.0058
Loa Loa (eye worm) bromodomain containing protein 0.004 0.0017 0.0018
Onchocerca volvulus 0.0027 0.0006 0.0035
Schistosoma mansoni cathepsin s 0.0603 0.0507 0.0507
Brugia malayi EF hand family protein 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0031 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus multilocularis Rac GTPase activating protein 1 0.0054 0.003 0.0049
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis expressed protein 0.0728 0.0616 0.1016
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1448 0.1241 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Loa Loa (eye worm) transcription factor SMAD2 0.0233 0.0185 0.0196
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Giardia lamblia Cathepsin B precursor 0.0426 0.0353 0.3119
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0026 0.0027
Onchocerca volvulus 0.0039 0.0017 0.01
Loa Loa (eye worm) prolyl oligopeptidase 0.0176 0.0136 0.0144
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0029 0.01
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0026 0.0043
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.011 0.011
Brugia malayi MH2 domain containing protein 0.0233 0.0185 0.0196
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Echinococcus multilocularis calpain family protein 1, d 0.0476 0.0397 0.0654
Schistosoma mansoni hypothetical protein 0.0054 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus granulosus cathepsin L cysteine proteinase 0.1915 0.1647 0.2717
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0012 0.0012
Schistosoma mansoni cathepsin F (C01 family) 0.1915 0.1647 0.1647
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0003 0.0003
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0002 0.0011
Schistosoma mansoni opsin-like receptor 0.0758 0.0641 0.0641
Echinococcus multilocularis lamin dm0 0.0027 0.0006 0.0009
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0135 0.01 0.0165
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0049 0.0049
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0006 0.01
Loa Loa (eye worm) hypothetical protein 0.1311 0.1123 0.1189
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0039 0.0016 0.009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0161
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Plasmodium vivax vivapain-2 0.1915 0.1647 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0264 0.0212 0.1226
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Loa Loa (eye worm) ctsf protein 0.1915 0.1647 0.1745
Brugia malayi calpain 7 0.0244 0.0195 0.0206
Entamoeba histolytica hypothetical protein 0.0076 0.0049 0.0295
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.0006
Onchocerca volvulus 0.0054 0.003 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0068 0.0112
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Giardia lamblia Cysteine protease 0.0426 0.0353 0.3119
Plasmodium falciparum serine repeat antigen 6 0.0426 0.0353 0.2144
Brugia malayi protein kinase C3,putative 0.006 0.0035 0.0037
Schistosoma mansoni calpain C (C02 family) 0.0244 0.0195 0.0195
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.0086 0.0142
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0536 0.0448 0.0739
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.103 0.0878 0.0878
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.0086 0.0789
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.1915 0.1647 1
Leishmania major kinesin, putative 0.0171 0.0131 0.0753
Brugia malayi Importin beta-1 subunit 0.0029 0.0008 0.0008
Onchocerca volvulus 0.0403 0.0333 0.202
Brugia malayi calpain 5 0.0073 0.0046 0.0049
Giardia lamblia Cathepsin L-like protease 0.0426 0.0353 0.3119
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0011 0.0018
Echinococcus granulosus TRP transient receptor potential channel 0.0042 0.0019 0.0031
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0758 0.0641 0.0641
Leishmania major calmodulin-like protein 0.0029 0.0008 0.0041
Loa Loa (eye worm) TYRA-2 protein 0.0758 0.0641 0.0679
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0592 0.0497 0.457
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Schistosoma mansoni transient receptor potential channel 0.0101 0.0071 0.0071
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0015 0.0025
Brugia malayi neuropeptide F receptor 0.0758 0.0641 0.0679
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0014 0.0083
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0007 0.0126
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0001 0.0004
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0001 0.002
Schistosoma mansoni hypothetical protein 0.0113 0.0081 0.0081
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0007 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0029 0.0029
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0022 0.0037
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0081 0.0053 0.0056
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0176 0.0136 0.0136
Brugia malayi Cathepsin L-like precursor 0.0603 0.0507 0.0537
Trypanosoma cruzi I/6 autoantigen, putative 0.0029 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.103 0.0878 0.3055
Echinococcus multilocularis fmrfamide receptor 0.0758 0.0641 0.1058
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0029 0.0008 0.0027
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.103 0.0878 0.3055
Brugia malayi Steroid receptor seven-up type 2 0.005 0.0026 0.0027
Schistosoma mansoni neuronal calcium sensor 0.0029 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0114 0.0082 0.0082
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0061 0.0035 0.0058
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.0677
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0176 0.0136 0.0823
Trypanosoma brucei calmodulin, putative 0.0029 0.0008 0.0041
Schistosoma mansoni steroid hormone receptor ad4bp 0.005 0.0026 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0013 0.0077
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0017 0.0017
Mycobacterium ulcerans proteasome PrcB 0.0081 0.0053 0.1059
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0014 0.0047
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0015 0.0025
Onchocerca volvulus 0.0758 0.0641 0.3893
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0053 0.0088
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0007 0.0126
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) PHD-finger family protein 0.0047 0.0023 0.0024
Echinococcus multilocularis sterol regulatory element binding protein 0.0133 0.0098 0.0162
Echinococcus granulosus EF hand domain containing family member A2 0.0029 0.0008 0.0013
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0153 0.0115 0.0122
Trypanosoma cruzi conserved protein 0.0073 0.0046 0.0161
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0026 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.0136 0.0472
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0006 0.012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.0353 0.0353
Plasmodium vivax hypothetical protein, conserved 0.0176 0.0136 0.0823
Brugia malayi Nuclear hormone receptor family member nhr-40 0.005 0.0026 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Toxoplasma gondii cathepsin CPC1 0.0426 0.0353 0.2144
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.005 0.0026 0.0043
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0013 0.0255
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0107 0.0076 0.0124
Onchocerca volvulus 0.0737 0.0623 0.3782
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0426 0.0353 0.2144
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis calcium binding protein, putative 0.0029 0.0008 0.0048
Brugia malayi G protein-coupled receptor F59B2.13 0.0758 0.0641 0.0679
Brugia malayi excitatory GABA receptor EXP-1A 0.0063 0.0038 0.004
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Echinococcus multilocularis cysteine protease 0.1915 0.1647 0.2717
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0012 0.0019
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.1123
Schistosoma mansoni intermediate filament proteins 0.0027 0.0006 0.0006
Echinococcus multilocularis cathepsin b 0.3325 0.2873 0.4739
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0015 0.0278
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0244 0.0195 0.0677
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Echinococcus multilocularis sodium and chloride dependent glycine 0.2752 0.2375 0.3918
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1323 0.1132 0.6556
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0004 0.0004
Brugia malayi hypothetical protein 0.0024 0.0004 0.0004
Trypanosoma cruzi centrin, putative 0.0029 0.0008 0.0027
Loa Loa (eye worm) RasGEF domain-containing protein 0.0054 0.003 0.0031
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0005 0.0103
Trypanosoma brucei kinesin, putative 0.0171 0.0131 0.0753
Brugia malayi PHD-finger family protein 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.1311 0.1123 0.1189
Onchocerca volvulus Legumain homolog 0.0147 0.011 0.0667
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0003 0.0016
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0758 0.0641 0.0679
Onchocerca volvulus 0.0758 0.0641 0.3893
Leishmania major proteasome beta 2 subunit, putative 0.0039 0.0016 0.009
Brugia malayi Thioredoxin family protein 0.0034 0.0013 0.0013
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0592 0.0497 1
Schistosoma mansoni diacylglycerol kinase theta 0.0054 0.003 0.003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0183 0.0141 0.015
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0016 0.0099
Onchocerca volvulus 0.0147 0.0111 0.0672
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0013 0.0046
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Echinococcus multilocularis cathepsin L 0.103 0.0878 0.1448
Schistosoma mansoni hypothetical protein 0.0758 0.0641 0.0641
Brugia malayi nuclear receptor RXR 0.0024 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Echinococcus granulosus protein kinase c epsilon type 0.006 0.0035 0.0058
Leishmania major hypothetical protein, conserved 0.0029 0.0008 0.0041
Plasmodium vivax importin-beta 2, putative 0.0029 0.0008 0.0044
Onchocerca volvulus 0.0035 0.0013 0.0078
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0074 0.0674
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0676 0.057 0.057
Loa Loa (eye worm) cysteine protease 0.1915 0.1647 0.1745
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0035 0.0013 0.0022
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0015 0.0016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0003 0.0005
Trichomonas vaginalis calcium binding protein, putative 0.0029 0.0008 0.0048
Loa Loa (eye worm) hypothetical protein 0.0061 0.0035 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0068 0.0112
Giardia lamblia Transglutaminase/protease, putative 0.0034 0.0013 0.0109
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0013 0.0014
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0007 0.001
Loa Loa (eye worm) EF hand family protein 0.0029 0.0008 0.0008
Echinococcus multilocularis tumor protein p63 0.1007 0.0858 0.1416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Schistosoma mansoni vesicular acetylcholine transporter 0.0214 0.0169 0.0169
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Schistosoma mansoni hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0015 0.0015
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0426 0.0353 0.2144
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0013 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Brugia malayi conserved hypotetical protein 0.0024 0.0003 0.0003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.2752 0.2375 0.2516
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis myotubularin protein 13 0.0054 0.003 0.0049
Toxoplasma gondii cathepsin CPL 0.1915 0.1647 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0426 0.0353 0.0374
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0603 0.0507 0.0537
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0016 0.0099
Leishmania major cysteine peptidase A (CPA) 0.1915 0.1647 0.9538
Loa Loa (eye worm) calmodulin-like protein 0.0029 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0027 0.0006 0.012
Schistosoma mansoni hypothetical protein 0.0073 0.0046 0.0046
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.005 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0014 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Leishmania major cathepsin L-like protease 0.1915 0.1647 0.9538
Brugia malayi nuclear receptor RXR 0.0026 0.0006 0.0006
Trypanosoma brucei centrin, putative 0.0029 0.0008 0.0041
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.006 0.0035 0.0037
Onchocerca volvulus 0.0024 0.0004 0.0022
Trypanosoma cruzi kinesin, putative 0.0171 0.0131 0.0455
Brugia malayi neuropeptide F receptor 0.0758 0.0641 0.0679
Schistosoma mansoni calmodulin related calcium binding protein 0.0029 0.0008 0.0008
Echinococcus multilocularis neuronal calcium sensor 0.0029 0.0008 0.0013
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0013 0.0014
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0536 0.0448 0.0448
Echinococcus granulosus g protein coupled receptor 0.0758 0.0641 0.1058
Brugia malayi glutaminase DH11.1 0.026 0.0209 0.0221
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0068 0.0112
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0007 0.0058
Loa Loa (eye worm) solute carrier family 6 member 4 0.0536 0.0448 0.0475
Loa Loa (eye worm) hypothetical protein 0.0132 0.0097 0.0102
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0029 0.0008 0.0048
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.2752 0.2375 0.2516
Loa Loa (eye worm) RGS-3 protein 0.0037 0.0015 0.0016
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3325 0.2873 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0426 0.0353 0.2144
Trichomonas vaginalis ran, putative 0.0021 0.0001 0.0005
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0034 0.0012 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.005 0.0026 0.0027
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0007 0.0022
Giardia lamblia Cathepsin B precursor 0.1323 0.1132 1
Brugia malayi Raf kinase 0.1503 0.1289 0.1366
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0031 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Echinococcus multilocularis thyroid hormone receptor alpha 0.005 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Onchocerca volvulus 0.0034 0.0013 0.0075
Onchocerca volvulus 0.0147 0.0111 0.0671
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0013 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426 0.0353 0.2144
Brugia malayi hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0013 0.0255
Brugia malayi MAP kinase sur-1 0.0055 0.0031 0.0032
Echinococcus granulosus g protein coupled receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0133 0.0098 0.0104
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0038 0.004
Brugia malayi hypothetical protein 0.0118 0.0085 0.009
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0007 0.0126
Brugia malayi Serotonin/octopamine receptor family protein 7 1.0878 0.9439 1
Leishmania major cytochrome p450-like protein 0.0028 0.0007 0.0033
Onchocerca volvulus 0.0035 0.0013 0.0078
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0112 0.008 0.0132
Schistosoma mansoni sodium/chloride dependent transporter 0.2758 0.238 0.238
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0029 0.0048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0603 0.0507 0.0537
Trypanosoma cruzi major cysteine proteinase, putative 0.0426 0.0353 0.1229
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426 0.0353 0.2144
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0003 0.0005
Schistosoma mansoni nAChR subunit 0.0063 0.0038 0.0038
Echinococcus granulosus lamin 0.0027 0.0006 0.0009
Toxoplasma gondii prolyl endopeptidase 0.1448 0.1241 0.7534
Leishmania major phosphatidylinositol 3-kinase, putative 0.0035 0.0013 0.0072
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0054 0.003 0.0049
Onchocerca volvulus 0.0063 0.0038 0.0228
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0031 0.0106
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Loa Loa (eye worm) raf kinase 0.155 0.133 0.1409
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Giardia lamblia Cathepsin B precursor 0.1323 0.1132 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0008 0.0048
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Echinococcus multilocularis conserved hypothetical protein 0.14 0.12 0.1979
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0031 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Brugia malayi Dopamine receptor 0.0758 0.0641 0.0679
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0015 0.0298
Trypanosoma cruzi cysteine proteinase, putative 0.103 0.0878 0.3055
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) melatonin receptor type 1A 0.0758 0.0641 0.0679
Echinococcus multilocularis calpain A 0.0676 0.057 0.0941
Entamoeba histolytica hypothetical protein 0.0023 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus Protein kinase C brain isozyme 0.006 0.0035 0.0058
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0214 0.0169 0.1025
Loa Loa (eye worm) neuropeptide F receptor 0.0758 0.0641 0.0679
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0074 0.0079
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0031 0.0268
Loa Loa (eye worm) calpain 5 0.0171 0.0131 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0758 0.0641 0.1058
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0509 0.0425 0.0701
Trichomonas vaginalis calcineurin B subunit, putative 0.0029 0.0008 0.0048
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0035 0.0013 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0758 0.0641 0.1058
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0015 0.0016
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0063 0.0038 0.004
Schistosoma mansoni Mername-AA248 (C02 family) 0.0244 0.0195 0.0195
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0056 0.0031 0.0033
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0038 0.0038
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0035 0.0013 0.008
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0039 0.0016 0.0016
Leishmania major oligopeptidase b 0.0592 0.0497 0.2876
Echinococcus granulosus neuronal calcium sensor 0.0029 0.0008 0.0013
Leishmania major pyruvate kinase 0.0037 0.0015 0.0082
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0426 0.0353 0.0374
Brugia malayi GnHR receptor homolog 0.0758 0.0641 0.0679
Schistosoma mansoni rac gtpase activating protein 0.0054 0.003 0.003
Trypanosoma brucei calpain, putative 0.0073 0.0046 0.0263
Echinococcus multilocularis neuropeptide receptor 0.0758 0.0641 0.1058
Echinococcus multilocularis calbindin 32 0.0029 0.0008 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Plasmodium vivax calpain, putative 0.0244 0.0195 0.1181
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.002
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.016 0.0122 0.2442
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0084 0.0767
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Entamoeba histolytica GPI-anchor transamidase, putative 0.0034 0.0012 0.0073
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.011 0.011
Echinococcus multilocularis neuropeptides capa receptor 0.0758 0.0641 0.1058
Schistosoma mansoni calpain-7 (C02 family) 0.0247 0.0197 0.0197
Echinococcus multilocularis g-protein coupled receptor 0.0758 0.0641 0.1058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Brugia malayi Peptidase C13 family protein 0.0147 0.011 0.0116
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0012 0.002
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0001 0.0001
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0004 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0758 0.0641 0.1058
Plasmodium vivax amine transporter, putative 0.0536 0.0448 0.272
Onchocerca volvulus Neuropeptide F receptor homolog 0.0758 0.0641 0.3893
Mycobacterium ulcerans glutaminase 0.026 0.0209 0.4189
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus multilocularis regulator of G protein signaling 0.0037 0.0015 0.0025
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0022 0.0002 0.001
Loa Loa (eye worm) DR-78 0.0024 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0426 0.0353 0.2144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.103 0.0878 0.5329
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0035 0.0013 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1311 0.1123 0.6815
Echinococcus granulosus nAChR subunit 0.0039 0.0017 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0015 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0006 0.0037
Echinococcus multilocularis pyruvate kinase 0.0029 0.0008 0.0013
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0031 0.0106
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0081 0.0053 0.0301
Echinococcus granulosus Niemann Pick C1 protein 0.0444 0.0368 0.0607
Brugia malayi programmed cell death protein 6 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Loa Loa (eye worm) norepinephrine transporter 0.0536 0.0448 0.0475
Echinococcus multilocularis somatostatin receptor 0.0758 0.0641 0.1058
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0013 0.0046
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0013 0.0021
Trypanosoma brucei calpain-like protein, putative 0.0244 0.0195 0.1123
Schistosoma mansoni ran 0.0021 0.0001 0.0001
Entamoeba histolytica hypothetical protein, conserved 0.0176 0.0136 0.0823
Trypanosoma cruzi calmodulin, putative 0.0029 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1915 0.1647 1
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0081 0.0053 0.032
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0081 0.0053 0.0484
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Plasmodium vivax centrin-1, putative 0.0029 0.0008 0.0047
Echinococcus multilocularis jun protein 0.0081 0.0053 0.0088
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0022 0.0036
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.011 0.0116
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Brugia malayi prolyl oligopeptidase family protein 0.1448 0.1241 0.1315
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0039 0.0016 0.0099
Echinococcus granulosus N chimaerin 0.0054 0.003 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0013 0.0117
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0039 0.0017 0.0017
Giardia lamblia Cathepsin B precursor 0.1323 0.1132 1
Schistosoma mansoni hypothetical protein 0.0355 0.0292 0.0292
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0003 0.0005
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0015 0.0025
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1175 0.1004 0.3496
Echinococcus granulosus 7tm_1 domain containing protein 0.0758 0.0641 0.1058
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Plasmodium vivax hypothetical protein, conserved 0.0536 0.0448 0.272
Brugia malayi calpain family protein 1 0.0647 0.0545 0.0577
Echinococcus multilocularis cysteine protease 0.1915 0.1647 0.2717
Giardia lamblia Cathepsin B precursor 0.0426 0.0353 0.3119
Leishmania major hypothetical protein, conserved 0.0035 0.0013 0.0069
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0017 0.0017
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0007 0.0126
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0063 0.0038 0.004
Echinococcus granulosus acylamino acid releasing enzyme 0.0176 0.0136 0.0224
Brugia malayi Cathepsin L-like precursor 0.1915 0.1647 0.1745
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Trypanosoma brucei antigen, putative 0.0244 0.0195 0.1123
Entamoeba histolytica hypothetical protein 0.0037 0.0015 0.0091
Schistosoma mansoni protein kinase C mu 0.006 0.0035 0.0035
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0001 0.0007
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0035 0.0013 0.0072
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.005 0.0026 0.0043
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0015 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0176 0.0136 0.0144
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0001 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0035 0.0035
Echinococcus granulosus Dipeptidyl peptidase 9 0.0264 0.0212 0.035
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0007 0.0058
Schistosoma mansoni hypothetical protein 0.0033 0.0012 0.0012
Brugia malayi hypothetical protein 0.0158 0.012 0.0127
Brugia malayi mbt repeat family protein 0.0053 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Toxoplasma gondii diacylglycerol kinase, putative 0.0054 0.003 0.018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0045 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1915 0.1647 1
Onchocerca volvulus 0.0021 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.5549 0.4806 0.5092
Trypanosoma cruzi kinesin, putative 0.0171 0.0131 0.0455
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0007 0.0106
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0003 0.0003
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0004 0.0004
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0592 0.0497 0.1731
Loa Loa (eye worm) hypothetical protein 0.0054 0.003 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.2007 0.1727 0.6011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Echinococcus multilocularis prolyl endopeptidase 0.1448 0.1241 0.2047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Echinococcus multilocularis FTZ F1 alpha 0.005 0.0026 0.0043
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0013 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0758 0.0641 0.3893
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0013 0.0117
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0063 0.0037 0.0225
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0012 0.0073
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0011 0.0066
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0017 0.0028
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Leishmania major cytochrome p450-like protein 0.0053 0.0029 0.0162
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.005 0.0026 0.0027
Echinococcus multilocularis pyruvate kinase 0.0037 0.0015 0.0025
Loa Loa (eye worm) CAMK/PKD protein kinase 0.006 0.0035 0.0037
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0536 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0061 0.0035 0.0058
Loa Loa (eye worm) proteasome subunit beta type 1 0.0063 0.0037 0.0039
Toxoplasma gondii calcium-dependent protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0021 0.0022
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0074 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Brugia malayi Papain family cysteine protease containing protein 0.1915 0.1647 0.1745
Loa Loa (eye worm) hypothetical protein 0.031 0.0252 0.0267
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Leishmania major centrin, putative 0.0029 0.0008 0.0041
Echinococcus multilocularis lamin 0.0027 0.0006 0.0009
Trichomonas vaginalis peptide N-glycanase, putative 0.0034 0.0013 0.0075
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0021 0.0033
Echinococcus multilocularis peregrin 0.0038 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0 0.000009889
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.006 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0007 0.0058
Trichomonas vaginalis calpain, putative 0.0073 0.0046 0.028
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.005 0.0026 0.0043
Schistosoma mansoni neuropeptide f receptor 76f 0.0758 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0758 0.0641 0.1058
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0015 0.0015
Onchocerca volvulus 0.0758 0.0641 0.3893
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426 0.0353 0.2144
Brugia malayi prolyl oligopeptidase family protein 0.0492 0.0411 0.0435
Echinococcus granulosus calmodulin 0.0029 0.0008 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0233 0.0185 0.0196
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0603 0.0507 0.0537
Loa Loa (eye worm) hypothetical protein 0.0147 0.0111 0.0117
Treponema pallidum DNA ligase (lig) 0.0021 0.0001 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0536 0.0448 0.0475
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0063 0.0038 0.004
Echinococcus granulosus hypothetical protein 0.2158 0.1859 0.3066
Trypanosoma brucei cysteine peptidase, putative 0.0073 0.0046 0.0263
Onchocerca volvulus 0.0758 0.0641 0.3893
Plasmodium falciparum serine repeat antigen 4 0.0426 0.0353 0.2144
Trypanosoma cruzi calmodulin, putative 0.0029 0.0008 0.0027
Onchocerca volvulus 0.0426 0.0353 0.2144
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0063 0.0383
Echinococcus granulosus neuropeptide Y receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) calpain 0.0244 0.0195 0.0206
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0005 0.0032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1323 0.1132 0.6875
Loa Loa (eye worm) hypothetical protein 0.0079 0.0051 0.0054
Brugia malayi DKFZp564C0469 protein 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0027
Brugia malayi jmjC domain containing protein 0.0044 0.0021 0.0022
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0008
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0029 0.0008 0.0013
Plasmodium falciparum serine repeat antigen 5 0.0426 0.0353 0.2144
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0045 0.0048
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0536 0.0448 0.0448
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0004 0.0006
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0012 0.0073
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0031 0.0172
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0005 0.0026
Onchocerca volvulus 0.0053 0.0029 0.0175
Echinococcus multilocularis short transient receptor potential channel 6 0.0069 0.0043 0.007
Trypanosoma cruzi I/6 autoantigen, putative 0.0029 0.0008 0.0027
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1448 0.1241 0.1241
Echinococcus multilocularis mitogen activated protein kinase 11 0.1175 0.1004 0.1657
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0001 0.0001
Echinococcus multilocularis Niemann Pick C1 protein 0.031 0.0252 0.0416
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.005 0.0026 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0536 0.0448 0.0475
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0014 0.0083
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0214 0.0169 0.0179
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0063 0.0037 0.0225
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0013 0.0014
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0006 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Echinococcus granulosus peregrin 0.0038 0.0016 0.0026
Schistosoma mansoni neuropeptide receptor 0.0758 0.0641 0.0641
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0063 0.0038 0.004
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0006 0.0006
Echinococcus granulosus mitogen activated protein kinase 14 0.1175 0.1004 0.1657
Echinococcus granulosus expressed protein 0.0728 0.0616 0.1016
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0082 0.0135
Onchocerca volvulus Prolyl endopeptidase homolog 0.1448 0.1241 0.7534
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0035 0.0013 0.0072
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0039 0.0016 0.0016
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0063 0.0038 0.0062
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0492 0.0411 0.0677
Brugia malayi PHD-finger family protein 0.0057 0.0032 0.0033
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0046 0.0263
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0006 0.0006
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0081 0.0053 0.0466
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0039 0.0017 0.0017
Echinococcus granulosus protein kinase c eta type 0.0054 0.003 0.0049
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0063 0.0037 0.021
Schistosoma mansoni biogenic amine (5HT) receptor 0.3081 0.2661 0.2661
Brugia malayi larval opioid receptor 0.0758 0.0641 0.0679
Echinococcus multilocularis g protein coupled receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.006 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0001 0.0002
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.0353 0.0353
Echinococcus granulosus alpha 1A adrenergic receptor 0.0758 0.0641 0.1058
Schistosoma mansoni hypothetical protein 0.0033 0.0011 0.0011
Echinococcus multilocularis calmodulin 0.0029 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0033 0.0012 0.0012
Brugia malayi proteasome subunit beta type 2 0.0039 0.0016 0.0017
Schistosoma mansoni hypothetical protein 0.0306 0.0249 0.0249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Entamoeba histolytica calpain large subunit domain III containing protein 0.0171 0.0131 0.0794
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0046 0.0161
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0031 0.0032
Schistosoma mansoni bromodomain containing protein 0.0144 0.0107 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0001 0.0003
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0029 0.0175
Brugia malayi EF hand family protein 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0022 0.0036
Schistosoma mansoni biogenic amine receptor 0.0758 0.0641 0.0641
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Toxoplasma gondii ABC1 family protein 0.0035 0.0013 0.0078
Schistosoma mansoni topbp1 0.0021 0.0001 0.0001
Brugia malayi PAS domain containing protein 0.0047 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0014 0.0083
Loa Loa (eye worm) hypothetical protein 0.0087 0.0058 0.0062
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0013 0.008
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0015 0.0025
Echinococcus granulosus short transient receptor potential channel 6 0.007 0.0043 0.0071
Schistosoma mansoni survival motor neuron protein 0.0153 0.0115 0.0115
Plasmodium vivax vivapain-1 0.103 0.0878 0.5329
Onchocerca volvulus Cathepsin L homolog 0.1915 0.1647 1
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0147 0.0111 0.0117
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0015 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0097 0.0097
Echinococcus multilocularis cathepsin L cysteine protease 0.1915 0.1647 0.2717
Plasmodium vivax vivapain-3 0.103 0.0878 0.5329
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0013 0.0117
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Trypanosoma brucei calmodulin, putative 0.0029 0.0008 0.0041
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.011 0.0667
Entamoeba histolytica calmodulin, putative 0.0029 0.0008 0.0048
Echinococcus multilocularis GPCR, family 2 0.0033 0.0012 0.0019
Echinococcus granulosus sodium and chloride dependent glycine 0.2752 0.2375 0.3918
Echinococcus granulosus EF hand domain containing family member A2 0.0029 0.0008 0.0013
Loa Loa (eye worm) G-protein coupled receptor 0.0758 0.0641 0.0679
Trypanosoma brucei Calpain-like protein 1.2 0.0073 0.0046 0.0263
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0038 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Brugia malayi Bromodomain containing protein 0.0087 0.0058 0.0061
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0038 0.0062
Trypanosoma cruzi cysteine peptidase, putative 0.2007 0.1727 0.6011
Entamoeba histolytica diacylglycerol kinase, putative 0.0054 0.003 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426 0.0353 0.2144
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0063 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Entamoeba histolytica hypothetical protein 0.0076 0.0049 0.0295
Brugia malayi cathepsin F-like cysteine proteinase 0.0603 0.0507 0.0537
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426 0.0353 0.2144
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Echinococcus granulosus tm gpcr rhodopsin 0.6993 0.6061 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0006 0.0006
Echinococcus multilocularis Protein kinase C, brain isozyme 0.006 0.0035 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0758 0.0641 0.1058
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0015 0.0015
Echinococcus granulosus cathepsin b 0.3325 0.2873 0.4739
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0001 0.0002
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1175 0.1004 0.5813
Loa Loa (eye worm) hypothetical protein 0.1915 0.1647 0.1745
Trypanosoma cruzi caltractin, putative 0.0029 0.0008 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-49 0.005 0.0026 0.0027
Onchocerca volvulus 0.0064 0.0038 0.0231
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0015 0.009
Plasmodium falciparum serine repeat antigen 8 0.0426 0.0353 0.2144
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.103 0.0878 0.0878
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0038 0.0062
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.0677
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0086 0.0086
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0264 0.0212 0.035
Echinococcus multilocularis G protein coupled receptor 139 0.0758 0.0641 0.1058
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0035 0.0035
Brugia malayi cathepsin L-like precursor 0.1311 0.1123 0.1189
Plasmodium falciparum cysteine proteinase falcipain 3 0.1915 0.1647 1
Schistosoma mansoni ap endonuclease 0.0021 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0007 0.0058
Schistosoma mansoni opsin-like receptor 0.0758 0.0641 0.0641
Entamoeba histolytica cysteine protease, putative 0.0426 0.0353 0.2144
Entamoeba histolytica cysteine proteinase, putative 0.1915 0.1647 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0035 0.0013 0.0022
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0001 0.0004
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Echinococcus multilocularis calmodulin 0.0029 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1915 0.1647 1
Brugia malayi Pre-SET motif family protein 0.0093 0.0063 0.0067
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0264 0.0212 0.0212
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.1311 0.1123 0.1189
Echinococcus multilocularis calcium uptake protein 1 0.0029 0.0008 0.0013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0758 0.0641 0.0641
Brugia malayi hypothetical protein 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0086 0.1728
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0005 0.01
Brugia malayi Melatonin receptor type 1A 0.0758 0.0641 0.0679
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0001 0.0004
Leishmania major calpain protease-like protein 0.0073 0.0046 0.0263
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0073 0.0046 0.0161
Trypanosoma cruzi 20S proteasome subunit 0.0039 0.0016 0.0057
Trichomonas vaginalis glutaminase, putative 0.026 0.0209 0.1265
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0015 0.0091
Echinococcus multilocularis serotonin transporter 0.0536 0.0448 0.0739
Trypanosoma brucei centrin-3 0.0029 0.0008 0.0041
Brugia malayi jmjC domain containing protein 0.0107 0.0076 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.0758 0.0641 0.1058
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0063 0.0037 0.0061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426 0.0353 0.2144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0426 0.0353 0.0374
Mycobacterium tuberculosis Conserved protein 0.0035 0.0013 0.0117
Brugia malayi calpain family protein 1 0.0647 0.0545 0.0577
Echinococcus multilocularis zinc finger protein 0.0044 0.0021 0.0035
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.0086 0.0494
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0014 0.0022
Echinococcus granulosus neuropeptide s receptor 0.0758 0.0641 0.1058
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0758 0.0641 0.0641
Schistosoma mansoni neuronal calcium sensor 0.0029 0.0008 0.0008
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0022 0.0078
Schistosoma mansoni sodium/chloride dependent transporter 0.0536 0.0448 0.0448
Brugia malayi prolyl oligopeptidase family protein 0.0264 0.0212 0.0225
Echinococcus granulosus mitogen activated protein kinase 11 0.1175 0.1004 0.1657
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0014 0.0022
Leishmania major cathepsin L-like protease 0.1915 0.1647 0.9538
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0426 0.0353 0.2144
Schistosoma mansoni biogenic amine (5HT) receptor 0.5549 0.4806 0.4806
Entamoeba histolytica cysteine proteinase, putative 0.103 0.0878 0.5329
Onchocerca volvulus Cathepsin F homolog 0.1915 0.1647 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0007 0.0058
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0013 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0013 0.0044
Onchocerca volvulus 0.0035 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.1448 0.1241 0.1315
Schistosoma mansoni diacylglycerol kinase theta 0.0054 0.003 0.003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.6993 0.6061 1
Toxoplasma gondii cathepsin CPC2 0.0426 0.0353 0.2144
Echinococcus granulosus cathepsin L 0.0426 0.0353 0.0583
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.005 0.0026 0.0027
Echinococcus multilocularis calpain 7 (C02 family) 0.0244 0.0195 0.0321
Onchocerca volvulus 0.0029 0.0008 0.0048
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0053 0.0088
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0082 0.0053 0.0088
Echinococcus granulosus tumor protein p63 0.1007 0.0858 0.1416
Brugia malayi sulfakinin receptor protein 0.0758 0.0641 0.0679
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0074 0.1457
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0005 0.0103
Loa Loa (eye worm) hypothetical protein 0.0403 0.0333 0.0352
Treponema pallidum fructose-bisphosphate aldolase 0.0327 0.0267 0.5954
Schistosoma mansoni ap endonuclease 0.0021 0.0001 0.0001
Plasmodium vivax serine-repeat antigen (SERA) 0.0426 0.0353 0.2144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0014 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.2438 0.2102 0.3468
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Treponema pallidum sodium- and chloride- dependent transporter 0.0536 0.0448 1
Echinococcus granulosus vesicular acetylcholine transporter 0.0214 0.0169 0.0279
Schistosoma mansoni centrin-related 0.0029 0.0008 0.0008
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0003 0.0003
Onchocerca volvulus 0.0758 0.0641 0.3893
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0592 0.0497 0.2876
Echinococcus multilocularis neuropeptides capa receptor 0.0758 0.0641 0.1058
Brugia malayi Papain family cysteine protease containing protein 0.0426 0.0353 0.0374
Schistosoma mansoni hypothetical protein 0.0128 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0006 0.012
Brugia malayi bZIP transcription factor family protein 0.0081 0.0053 0.0056
Schistosoma mansoni jumonji domain containing protein 0.0085 0.0056 0.0056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0758 0.0641 0.0679
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0073 0.0046 0.0161
Brugia malayi nuclear receptor NHR-88 0.005 0.0026 0.0027
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0031 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0035 0.0035
Echinococcus multilocularis protein patched 0.0133 0.0098 0.0162
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0031 0.0106
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0006 0.0031
Trichomonas vaginalis calmodulin, putative 0.0029 0.0008 0.0048
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0046 0.0161
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0015 0.0016
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0037 0.0015 0.0015
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Mycobacterium tuberculosis Conserved protein 0.0035 0.0013 0.0117
Giardia lamblia Cysteine protease 0.0426 0.0353 0.3119
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0001 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.1311 0.1123 0.6815
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0536 0.0448 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0883 0.075 0.0795
Schistosoma mansoni myosin xvIII 0.0758 0.0641 0.0641
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0013 0.0113
Brugia malayi fibroinase precursor 0.0426 0.0353 0.0374
Leishmania major calmodulin, putative 0.0029 0.0008 0.0041
Onchocerca volvulus 0.0054 0.003 0.018
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0034 0.0012 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0006 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0178 0.0137 0.0478
Echinococcus granulosus calpain A 0.0676 0.057 0.0941
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.005 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0014
Brugia malayi tailless protein 0.0024 0.0003 0.0003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0082 0.0135
Giardia lamblia Cathepsin L precursor 0.0426 0.0353 0.3119
Onchocerca volvulus 0.1915 0.1647 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0059 0.0063
Entamoeba histolytica protein kinase, putative 0.0177 0.0136 0.0827
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3325 0.2873 0.2873
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426 0.0353 0.2144
Entamoeba histolytica hypothetical protein 0.0021 0.0001 0.0007
Leishmania major phospholipase c-like protein 0.0029 0.0008 0.0041
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.005 0.0026 0.0026
Plasmodium falciparum phd finger protein, putative 0.0033 0.0011 0.0065
Entamoeba histolytica cysteine protease, putative 0.103 0.0878 0.5329
Echinococcus granulosus cathepsin l1 0.1311 0.1123 0.1852
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0063 0.0037 0.0129
Loa Loa (eye worm) calpain D 0.0073 0.0046 0.0049
Brugia malayi Bromodomain containing protein 0.0038 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0308 0.025 0.0265
Trypanosoma brucei prolyl endopeptidase 0.1448 0.1241 0.7185
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0536 0.0448 0.272
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0007 0.0126
Mycobacterium ulcerans transglutaminase family protein 0.0034 0.0013 0.0247
Brugia malayi Ras association domain family 1 isoform A 0.0054 0.003 0.0031
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0001 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0758 0.0641 0.1058
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0015 0.0016
Echinococcus granulosus serotonin transporter 0.0536 0.0448 0.0739
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0004 0.0004
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0001 0.0001
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0039 0.0016 0.0099
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0007 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0267 0.1622
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0426 0.0353 0.2144
Trichomonas vaginalis conserved hypothetical protein 0.0176 0.0136 0.0823
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0039 0.0016 0.0057
Trichomonas vaginalis calpain, putative 0.0073 0.0046 0.028
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0758 0.0641 0.0641
Echinococcus multilocularis cathepsin b 0.3325 0.2873 0.4739
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0074 0.0674
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0038 0.0062
Echinococcus granulosus allatostatin A receptor 0.0758 0.0641 0.1058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0758 0.0641 0.1058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0022 0.0024
Leishmania major calmodulin-like protein 0.0029 0.0008 0.0041
Loa Loa (eye worm) serotonin transporter b 0.0536 0.0448 0.0475
Schistosoma mansoni cathepsin S (C01 family) 0.0426 0.0353 0.0353
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0758 0.0641 0.1058
Echinococcus granulosus neuropeptide receptor 0.0758 0.0641 0.1058
Plasmodium vivax serine-repeat antigen (SERA) 0.0426 0.0353 0.2144
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0063 0.0038 0.0062
Plasmodium falciparum serine repeat antigen 2 0.0426 0.0353 0.2144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Schistosoma mansoni zinc finger protein 0.0035 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0031 0.005
Echinococcus granulosus snurportin 1 0.0306 0.0249 0.041
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0007
Brugia malayi calpain D 0.0073 0.0046 0.0049
Brugia malayi hypothetical protein 0.0758 0.0641 0.0679
Echinococcus multilocularis centrin 2 0.0029 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0033 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Plasmodium falciparum GPI-anchor transamidase, putative 0.0034 0.0012 0.0072
Echinococcus granulosus calpain A 0.0244 0.0195 0.0321
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0011 0.0011
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0007 0.0058
Toxoplasma gondii preprocathepsin c precursor, putative 0.0426 0.0353 0.2144
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0153 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0758 0.0641 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.1123
Trichomonas vaginalis calcium binding proteins, putative 0.0029 0.0008 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.005 0.0026 0.0027
Plasmodium vivax proteasome subunit beta type-5, putative 0.0081 0.0053 0.032
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0029 0.0162
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0015 0.0025
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0001 0.0007
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0063 0.0037 0.0225
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Onchocerca volvulus 0.0758 0.0641 0.3893
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0026 0.0027
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0073 0.0046 0.028
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0015 0.0016
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0035 0.0013 0.0072
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0063 0.0038 0.0062
Plasmodium falciparum serine repeat antigen 1 0.0426 0.0353 0.2144
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0029 0.003
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0063 0.0038 0.004
Echinococcus granulosus neuropeptide FF receptor 2 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0758 0.0641 0.0679
Loa Loa (eye worm) prolyl oligopeptidase 0.0492 0.0411 0.0435
Schistosoma mansoni transient receptor potential channel 4 0.0101 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Schistosoma mansoni vav2 0.0054 0.003 0.003
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0035 0.0035
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.0677
Loa Loa (eye worm) hypothetical protein 0.0034 0.0012 0.0013
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0021 0.0033
Echinococcus granulosus sex peptide receptor 0.0758 0.0641 0.1058
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0492 0.0411 0.0677
Brugia malayi Dopamine receptor protein 2 0.0758 0.0641 0.0679
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0073 0.0046 0.0161
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0073 0.0046 0.0263
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0054 0.003 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426 0.0353 0.2144
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0426 0.0353 0.2144
Trypanosoma brucei Calpain-like protein 2 0.0073 0.0046 0.0263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0758 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.004
Echinococcus granulosus nibrin 0.0021 0.0001 0.0002
Schistosoma mansoni atypical protein kinase C 0.006 0.0035 0.0035
Onchocerca volvulus 0.0063 0.0038 0.0228
Echinococcus multilocularis mitogen activated protein kinase 14 0.1175 0.1004 0.1657
Echinococcus granulosus intermediate filament protein 0.0027 0.0006 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1323 0.1132 0.1132
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.005 0.0026 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0013 0.0117
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0005 0.0114
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0001 0.0007
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0007 0.0126
Brugia malayi A-kinase anchor protein 10, precursor 0.0037 0.0015 0.0016
Echinococcus multilocularis transient receptor potential ion channel A 0.0091 0.0062 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2007 0.1727 1
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0039 0.0016 0.0098
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0013 0.0117
Loa Loa (eye worm) hypothetical protein 0.0053 0.0029 0.0031
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0001 0.0004
Schistosoma mansoni transient receptor potential channel 0.0069 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0244 0.0195 0.1123
Echinococcus granulosus neuropeptides capa receptor 0.0758 0.0641 0.1058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0016
Mycobacterium tuberculosis Conserved protein 0.0035 0.0013 0.0117
Brugia malayi Cation transporter family protein 0.0063 0.0038 0.004
Echinococcus multilocularis Diacylglycerol kinase theta 0.0054 0.003 0.0049
Schistosoma mansoni hypothetical protein 0.0028 0.0007 0.0007
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0008 0.0038
Schistosoma mansoni rab 0.0029 0.0008 0.0008
Brugia malayi CHE-14 protein 0.0133 0.0098 0.0104
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0758 0.0641 0.1058
Schistosoma mansoni pyruvate kinase 0.0037 0.0015 0.0015
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0426 0.0353 0.0374
Brugia malayi hypothetical protein 0.0024 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1915 0.1647 1
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0029 0.0008 0.0008
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0035 0.0013 0.0072
Echinococcus granulosus GPCR family 2 0.0033 0.0012 0.0019
Plasmodium vivax unspecified product 0.0603 0.0507 0.3078
Mycobacterium leprae Conserved hypothetical protein 0.0034 0.0013 0.0228
Onchocerca volvulus 0.0063 0.0038 0.0228
Brugia malayi hypothetical protein 0.0024 0.0004 0.0004

Activities

Activity type Activity value Assay description Source Reference
IA (functional) = 8 % The percent intrinsic activity, determined by level of antagonist induced secretion ChEMBL. 9357532
Relative potency (functional) = 0.12 In vitro relative potency versus [DPhe12,Nle21,38]-hCRF(12-41), using rat pituitary culture assay ChEMBL. 9357532

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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