Detailed information for compound 505605

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1646.73 | Formula: C78H95N13O25S
  • H donors: 14 H acceptors: 20 LogP: 1.12 Rotable bonds: 46
    Rule of 5 violations (Lipinski): 4
  • SMILES: COc1ccc(cc1OC)/C=N\O[C@@H]1C[C@H](N(C1)C(=O)C1CCCCN1C(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CCCCNC(=S)Nc1ccc2c(c1)C1(OC2=O)c2ccc(cc2Oc2c1ccc(c2)O)O)CCC(=O)O)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)O)CCC(=O)O
  • InChi: 1S/C78H95N13O25S/c1-40(73(108)90-30-8-6-11-56(90)75(110)91-39-46(116-81-38-42-15-25-58(112-3)61(33-42)113-4)37-57(91)71(106)85-52(23-27-64(98)99)68(103)84-51(67(79)102)22-26-63(96)97)82-72(107)66(41(2)92)87-70(105)55-13-10-32-89(55)74(109)53(24-28-65(100)101)86-69(104)54-12-9-31-88(54)62(95)14-5-7-29-80-77(117)83-43-16-19-47-50(34-43)78(115-76(47)111)48-20-17-44(93)35-59(48)114-60-36-45(94)18-21-49(60)78/h15-21,25,33-36,38,40-41,46,51-57,66,92-94H,5-14,22-24,26-32,37,39H2,1-4H3,(H2,79,102)(H,82,107)(H,84,103)(H,85,106)(H,86,104)(H,87,105)(H,96,97)(H,98,99)(H,100,101)(H2,80,83,117)/b81-38-/t40-,41+,46+,51-,52-,53-,54-,55-,56?,57-,66-/m0/s1
  • InChiKey: RAWJUEVVOMFGJB-VBSWMEIHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tumor susceptibility 101 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tumor susceptibility gene 101 protein Get druggable targets OG5_128950 All targets in OG5_128950
Echinococcus multilocularis tumor susceptibility gene 101 protein Get druggable targets OG5_128950 All targets in OG5_128950
Candida albicans weak similarity to S. cerevisiae STP22 putative ubiquitin receptor, and to mouse tumor susceiptibility protein TSG101 Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Entamoeba histolytica tumor susceptibility gene 101 protein, putative Get druggable targets OG5_128950 All targets in OG5_128950
Candida albicans weak similarity to S. cerevisiae STP22 putative ubiquitin receptor, and to mouse tumor susceiptibility protein TSG101 Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma japonicum Tumor susceptibility gene 101 protein, putative Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma mansoni tsg101-related Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma japonicum ko:K01931 tumor suppressor protein 101 [EC:6.3.2.19], putative Get druggable targets OG5_128950 All targets in OG5_128950
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
Brugia malayi hypothetical protein Get druggable targets OG5_128950 All targets in OG5_128950
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus neuropeptide receptor 0.0025 0.0059 0.0059
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0104 0.0868
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0132 0.0534 0.0534
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0025 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0035 0.0103 0.0103
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0035 0.0103 0.1622
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0009 0.0012
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0154 0.0632 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0025 0.0059 0.011
Giardia lamblia Kinase, PLK 0.0432 0.1872 1
Plasmodium falciparum glutathione reductase 0.0132 0.0534 0.2205
Echinococcus multilocularis zinc finger protein 0.0015 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0281 0.1198 0.1957
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0031 0.0084 0.0156
Entamoeba histolytica serine/threonine protein kinase, putative 0.0432 0.1872 1
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Plasmodium falciparum DNA mismatch repair protein PMS1, putative 0.0012 0 0.0002
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0112 0.0208
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0073 0.0272 0.0445
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0104 0.0412 0.0412
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0065 0.0238 0.0444
Echinococcus granulosus neuropeptide receptor A26 0.0654 0.2863 0.2863
Mycobacterium ulcerans acyl-CoA synthetase 0.0068 0.0248 0.2071
Loa Loa (eye worm) hypothetical protein 0.0058 0.0206 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0209 0.1118
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.0049 0.026
Schistosoma mansoni growth hormone secretagogue receptor 0.0025 0.0059 0.0078
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0049 0.0204
Trypanosoma cruzi cytochrome P450, putative 0.0065 0.0236 0.1262
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0035 0.0103 0.055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0128 0.0516 0.0516
Schistosoma mansoni DNA topoisomerase II 0.0026 0.0061 0.0081
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0159 0.0847
Echinococcus granulosus Smad4 0.0017 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.012 0.0159
Onchocerca volvulus 0.0025 0.0059 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Onchocerca volvulus 0.0227 0.0957 0.1563
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0014 0.0008 0.0113
Schistosoma mansoni rab6-interacting 0.0013 0.0005 0.0007
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0272 0.0507
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0008 0.0041
Toxoplasma gondii phosphofructokinase PFKII 0.0076 0.0285 0.1177
Toxoplasma gondii heat shock protein 75, putative 0.0105 0.0416 0.1718
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0076 0.0285 0.0603
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0032 0.0089 0.0366
Trypanosoma brucei polo-like protein kinase 0.0432 0.1872 1
Brugia malayi Bromodomain containing protein 0.0027 0.0068 0.0126
Onchocerca volvulus 0.0025 0.0059 0.0097
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0867 0.3811 0.8982
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0104 0.0556
Schistosoma mansoni ap endonuclease 0.004 0.0124 0.0165
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0209 0.0864
Brugia malayi hypothetical protein 0.0384 0.1659 0.3087
Onchocerca volvulus 0.0015 0.0013 0.0022
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0035 0.0103 0.0548
Schistosoma mansoni ap endonuclease 0.004 0.0124 0.0165
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0026 0.0061 0.009
Brugia malayi TAR-binding protein 0.017 0.0707 0.1315
Entamoeba histolytica heat shock transcription factor, putative 0.0015 0.0014 0.0076
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0035 0.0103 0.0103
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0059 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0029 0.0156
Entamoeba histolytica phosphofructokinase, putative 0.0281 0.1198 0.6402
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0025 0.0059 0.0097
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0035 0.0103 0.0103
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0059 0.0059
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0104 0.0868
Brugia malayi regulator of G-protein signaling rgs-7 0.0037 0.0112 0.0208
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Onchocerca volvulus 0.0025 0.0059 0.0097
Plasmodium falciparum ferrodoxin reductase-like protein 0.0035 0.0103 0.0425
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Trichomonas vaginalis mismatch repair protein Mlh3 (mutL homolog) 0.0012 0 0.0001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0017 0.0092
Brugia malayi Isocitrate dehydrogenase 0.005 0.0168 0.0313
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0134 0.0249
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0026 0.0061 0.01
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.008 0.0303 0.0303
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0045 0.0374
Loa Loa (eye worm) hypothetical protein 0.0189 0.0788 0.1467
Trypanosoma cruzi NADH dehydrogenase, putative 0.0035 0.0103 0.055
Brugia malayi Nuclear hormone receptor E75 0.006 0.0215 0.0401
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0111 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0016
Brugia malayi Niemann-Pick C1 protein precursor 0.0136 0.0551 0.1026
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0104 0.0868
Loa Loa (eye worm) phosphofructokinase 0.0281 0.1198 0.2229
Mycobacterium leprae conserved hypothetical protein 0.0064 0.0231 0.0528
Brugia malayi AMP-binding enzyme family protein 0.002 0.0036 0.0066
Brugia malayi glutathione reductase 0.038 0.1641 0.3054
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0037 0.0111 0.0927
Brugia malayi hypothetical protein 0.0144 0.0589 0.1096
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0209 0.0209
Echinococcus multilocularis pyruvate kinase 0.0024 0.0052 0.0052
Onchocerca volvulus 0.0025 0.0059 0.0097
Echinococcus granulosus survival motor neuron protein 1 0.1031 0.4543 0.4543
Echinococcus granulosus expressed protein 0.0031 0.0084 0.0084
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0036 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0048
Plasmodium falciparum replication factor C subunit 1, putative 0.0014 0.0008 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0128 0.0516 0.0959
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0168 0.0694
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0209 0.1118
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0035 0.0103 0.055
Echinococcus granulosus flap endonuclease 1 0.0032 0.0089 0.0089
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0142 0.0579 0.0579
Onchocerca volvulus 0.0042 0.0134 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Brugia malayi sulfakinin receptor protein 0.0025 0.0059 0.011
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0059 0.0059
Toxoplasma gondii microneme protein MIC17B 0.0015 0.0013 0.0055
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Loa Loa (eye worm) hypothetical protein 0.1031 0.4543 0.8452
Schistosoma mansoni tsg101-related 0.007 0.0259 0.0343
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0035 0.0103 0.0225
Onchocerca volvulus 0.002 0.0036 0.0058
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0085 0.045
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0059 0.0078
Leishmania major pyruvate kinase 0.0046 0.0152 0.0812
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0026 0.0061 0.009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0128 0.0519 0.0519
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0272 0.1455
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0112 0.0112
Schistosoma mansoni sulfide quinone reductase 0.0035 0.0103 0.0136
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0064 0.0231 0.0954
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0128 0.0516 0.0683
Brugia malayi AMP-binding enzyme family protein 0.0068 0.0248 0.0462
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0104 0.0191
Echinococcus multilocularis sodium channel protein 0.0029 0.0074 0.0074
Mycobacterium tuberculosis Probable dehydrogenase 0.0867 0.3811 0.8978
Loa Loa (eye worm) hypothetical protein 0.0073 0.0272 0.0507
Entamoeba histolytica elongation factor-2 kinase, putative 0.0042 0.0134 0.0715
Toxoplasma gondii pyruvate kinase PyK1 0.0046 0.0152 0.0627
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0052
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.008 0.0303 0.0401
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0032
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Brugia malayi hypothetical protein 0.0031 0.0084 0.0156
Loa Loa (eye worm) endoplasmin 0.0167 0.0693 0.1289
Echinococcus granulosus alkaline phosphatase 0.0104 0.0412 0.0412
Schistosoma mansoni methyl-cpg binding protein mbd 0.0012 0.0001 0.0001
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0067 0.0247 0.046
Onchocerca volvulus Pyruvate kinase homolog 0.0046 0.0152 0.0248
Trichomonas vaginalis heat shock protein, putative 0.0119 0.0477 0.0779
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0124 0.0203
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0076 0.0285 0.1177
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0061 0.0061
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Giardia lamblia Pyruvate kinase 0.0046 0.0152 0.0809
Trypanosoma cruzi heat shock protein 85, putative 0.0142 0.0579 0.3094
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.002 0.0036 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.0281 0.1198 0.6402
Toxoplasma gondii NAC domain-containing protein 0.0023 0.005 0.0207
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0105 0.0414 0.0414
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0042 0.0134 0.0552
Trichomonas vaginalis mercuric reductase, putative 0.0132 0.0534 0.0872
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.014 0.014
Trichomonas vaginalis glutamate synthase, putative 0.0035 0.0103 0.0168
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0048 0.0199
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0128 0.0516 0.0683
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0064 0.0231 0.1929
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0128 0.0519 0.0519
Brugia malayi hypothetical protein 0.0037 0.0112 0.0208
Echinococcus granulosus methyl CpG binding domain protein 2 0.0012 0.0001 0.0001
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0032 0.0059
Onchocerca volvulus Heat shock factor protein 2 homolog 0.024 0.1016 0.1659
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0059 0.0059
Echinococcus multilocularis serotonin receptor 0.0025 0.0059 0.0059
Schistosoma mansoni DNA helicase recq1 0.0031 0.0085 0.0112
Onchocerca volvulus Pyruvate kinase homolog 0.0046 0.0152 0.0248
Echinococcus granulosus heat shock transcription factor 0.0015 0.0014 0.0014
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0035 0.0103 0.055
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0763 0.101
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.019 0.0792 0.1049
Schistosoma mansoni amine GPCR 0.0025 0.0059 0.0078
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0005 0.0005
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0984 0.4333 0.5737
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0032 0.0042
Plasmodium vivax ataxin-2 like protein, putative 0.0047 0.0159 0.0654
Plasmodium vivax multidomain scavenger receptor, putative 0.0013 0.0005 0.0022
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0026 0.0063 0.0117
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0009 0.0015
Brugia malayi tailless protein 0.006 0.0215 0.0401
Brugia malayi heat shock protein 90 0.0167 0.0693 0.1289
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0124 0.1038
Loa Loa (eye worm) hypothetical protein 0.0384 0.1659 0.3087
Schistosoma mansoni cytochrome P450 0.0035 0.0104 0.0138
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0059 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.0052 0.018 0.0334
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.016 0.0324
Mycobacterium tuberculosis Conserved protein 0.0037 0.0111 0.0208
Echinococcus granulosus G protein coupled receptor 139 0.0025 0.0059 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.016 0.0324
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0005 0.0005
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.002 0.0036 0.0029
Onchocerca volvulus 0.0014 0.0008 0.0012
Plasmodium falciparum pyruvate kinase 2 0.0024 0.0052 0.0216
Trichomonas vaginalis apoptosis inducing factor, putative 0.0035 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0022 0.0022
Leishmania major ornithine decarboxylase, putative 0.0061 0.0219 0.1169
Echinococcus granulosus transcription factor Dp 1 0.0085 0.0324 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0014 0.0008 0.0041
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0035 0.0103 0.086
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0128 0.0516 0.0516
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0036 0.0058
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0044 0.0142 0.0757
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0035 0.0103 0.0189
Plasmodium falciparum acyl-CoA synthetase 0.005 0.0172 0.071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0025 0.0059 0.0078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0124 0.0665
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0025 0.0059 0.0078
Schistosoma mansoni heat shock protein 0.0167 0.0693 0.0918
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.002 0.0036 0.0036
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0026 0.0061 0.0128
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0128 0.0516 0.0683
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0048
Onchocerca volvulus Neuropeptide F receptor homolog 0.0025 0.0059 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Schistosoma mansoni hypothetical protein 0.0054 0.0189 0.025
Trichomonas vaginalis DNA polymerase eta, putative 0.0073 0.0272 0.0445
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0208
Loa Loa (eye worm) abnormal epIthelia family member 0.0052 0.018 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0128 0.0516 0.0959
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0009 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0036 0.019
Mycobacterium ulcerans acetyl-CoA synthetase 0.002 0.0036 0.0297
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0272 0.0272
Loa Loa (eye worm) pyruvate kinase-PB 0.0032 0.009 0.0167
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0104 0.0868
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0112 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0052 0.0085
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Toxoplasma gondii hypothetical protein 0.0015 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.0024 0.0053 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0059 0.0059
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0035 0.0103 0.055
Treponema pallidum heat shock protein 90 0.0154 0.0632 0.1339
Trichomonas vaginalis pyruvate kinase, putative 0.0046 0.0152 0.0248
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0318 0.0734
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0029 0.0074 0.0074
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0031 0.0084 0.0345
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0037 0.0111 0.0927
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0045 0.0073
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0055 0.0192 0.1024
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0048 0.0199
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0035 0.0103 0.055
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0318 0.0593
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.014 0.014
Echinococcus multilocularis ubiquitin specific protease 41 0.008 0.0303 0.0303
Onchocerca volvulus 0.0065 0.0238 0.0389
Schistosoma mansoni hypothetical protein 0.0026 0.0063 0.0084
Schistosoma mansoni biogenic amine receptor 0.0025 0.0059 0.0078
Entamoeba histolytica thioredoxin reductase, putative 0.0035 0.0103 0.055
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Onchocerca volvulus 0.0019 0.0032 0.0052
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0112 0.0112
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0064 0.0231 0.0489
Loa Loa (eye worm) glutaminase 0.0215 0.0904 0.1681
Plasmodium falciparum DNA mismatch repair protein MLH 0.0012 0 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Echinococcus multilocularis dna polymerase eta 0.0073 0.0272 0.0272
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0326 0.0532
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0227 0.0957 0.178
Trypanosoma brucei transcription factor BTF3, putative 0.0023 0.005 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Entamoeba histolytica hypothetical protein 0.0014 0.0009 0.0049
Plasmodium falciparum pyruvate kinase 0.0046 0.0152 0.0627
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0152
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0061 0.0326
Mycobacterium ulcerans epimerase 0.0022 0.0045 0.0374
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0272 0.0272
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0017 0.0092
Echinococcus multilocularis amyloid beta A4 protein 0.0048 0.0162 0.0162
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0059 0.0059
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0048 0.0257
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0172 0.1436
Toxoplasma gondii DNA mismatch repair protein, C-terminal domain-containing protein 0.0012 0 0.0002
Toxoplasma gondii NADPH-glutathione reductase 0.0132 0.0534 0.2205
Brugia malayi photoreceptor-specific nuclear receptor 0.0128 0.0516 0.0959
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0076 0.0285 0.0466
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0104 0.0868
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0035 0.0103 0.0192
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0073 0.0272 0.1455
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0215 0.0352
Echinococcus granulosus leukotriene A 4 hydrolase 0.0223 0.0942 0.0942
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0128 0.0516 0.0516
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Brugia malayi acetyl-Coenzyme A synthetase 2 0.002 0.0036 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0104 0.0191
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0035 0.0103 0.055
Schistosoma mansoni RAR-like nuclear receptor 0.0128 0.0516 0.0683
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0068 0.0248 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0012
Echinococcus multilocularis orexin receptor type 2 0.0025 0.0059 0.0059
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0318 0.1314
Loa Loa (eye worm) hypothetical protein 0.0227 0.0957 0.178
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Trypanosoma cruzi heat shock protein 90, putative 0.0142 0.0579 0.3094
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0104 0.0191
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0076 0.0285 0.1177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0092 0.015
Loa Loa (eye worm) hypothetical protein 0.0231 0.0975 0.1814
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0066
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0209 0.0209
Trypanosoma cruzi heat shock protein 85, putative 0.0167 0.0693 0.3702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0059 0.0059
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0035 0.0103 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0049 0.0264
Echinococcus granulosus pyruvate kinase 0.0024 0.0052 0.0052
Brugia malayi Smad1 0.0017 0.0022 0.0041
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0026 0.0061 0.0326
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0042 0.0134 0.0552
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Trypanosoma cruzi heat shock protein 90, putative 0.0167 0.0693 0.3702
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Trichomonas vaginalis ornithine decarboxylase, putative 0.0061 0.0219 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Schistosoma mansoni tyrosine kinase 0.0105 0.0414 0.0548
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0026 0.0061 0.0114
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0032 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0104 0.0191
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0104 0.0191
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0025 0.0059 0.0078
Brugia malayi N-terminal motif family protein 0.0129 0.0523 0.0973
Entamoeba histolytica DNA mismatch repair protein PMS1, putative 0.0012 0 0.0003
Echinococcus granulosus g protein coupled receptor 0.0025 0.0059 0.0059
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0059 0.0059
Treponema pallidum thioredoxin reductase (trxB) 0.0035 0.0103 0.0217
Echinococcus granulosus replication factor c subunit 1 0.0014 0.0008 0.0008
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0209 0.1118
Echinococcus multilocularis GPCR, family 3, C terminal 0.0015 0.0014 0.0014
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0009 0.0012
Trypanosoma cruzi heat shock protein 85, putative 0.0167 0.0693 0.3702
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0104 0.0191
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0136 0.0554 0.0733
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0128 0.0519 0.0965
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0146 0.0598 0.3197
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0159 0.0654
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0076 0.0285 0.1523
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0035 0.0103 0.0103
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0107 0.0569
Plasmodium falciparum thioredoxin reductase 0.038 0.1641 0.6773
Schistosoma mansoni thyroid hormone receptor 0.0253 0.1076 0.1425
Schistosoma mansoni neuropeptide receptor 0.0025 0.0059 0.0078
Echinococcus multilocularis neuropeptide s receptor 0.0654 0.2863 0.2863
Schistosoma mansoni tyrosine kinase 0.0105 0.0414 0.0548
Loa Loa (eye worm) pyridoxal-dependent decarboxylase 0.0061 0.0219 0.0407
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Trichomonas vaginalis heat shock protein, putative 0.0154 0.0632 0.1033
Onchocerca volvulus Pyruvate kinase homolog 0.0046 0.0152 0.0248
Echinococcus granulosus transcription factor btf3 0.0023 0.005 0.005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.0098 0.0406
Echinococcus granulosus pyruvate kinase 0.0046 0.0152 0.0152
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0035 0.0103 0.0103
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0128 0.0516 0.0516
Loa Loa (eye worm) nuclear receptor nhr-7B 0.006 0.0215 0.0401
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0067 0.0247 0.0247
Entamoeba histolytica acyl-CoA synthetase, putative 0.0068 0.0248 0.1326
Leishmania major hypothetical protein, conserved 0.0023 0.0049 0.0264
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0015 0.0014 0.0023
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0026 0.0061 0.01
Brugia malayi G-protein coupled receptor 0.0025 0.0059 0.011
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0215 0.0215
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0073 0.0272 0.0272
Echinococcus multilocularis flap endonuclease 1 0.0032 0.0089 0.0089
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0064 0.0231 0.0954
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni hypothetical protein 0.0144 0.0589 0.078
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0035 0.0103 0.0425
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Schistosoma mansoni biogenic amine receptor 0.0025 0.0059 0.0078
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0005 0.0005
Giardia lamblia Flap structure-specific endonuclease 0.0032 0.0089 0.0472
Loa Loa (eye worm) hypothetical protein 0.0071 0.0265 0.0493
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0132 0.0534 0.2205
Onchocerca volvulus 0.0015 0.0013 0.0022
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0085 0.0349
Brugia malayi Pax transcription activation domain interacting protein 0.0014 0.0008 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0048 0.0257
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0035 0.0103 0.0103
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0077 0.0292 0.0292
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Echinococcus multilocularis pikachurin 0.0052 0.018 0.018
Schistosoma mansoni amine GPCR 0.0025 0.0059 0.0078
Mycobacterium ulcerans ferredoxin reductase 0.0035 0.0103 0.086
Echinococcus granulosus pyruvate kinase 0.0046 0.0152 0.0152
Schistosoma mansoni Microrchidia 2a 0.0012 0 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0231 0.0975 0.1814
Brugia malayi Muscleblind-like protein 0.0096 0.0374 0.0697
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Loa Loa (eye worm) glutathione reductase 0.038 0.1641 0.3054
Echinococcus multilocularis lamin 0.0065 0.0238 0.0238
Toxoplasma gondii exonuclease III APE 0.004 0.0124 0.0513
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0068 0.0248 0.2071
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0272 0.2273
Brugia malayi Protein cec-1. 0.0014 0.0009 0.0017
Trypanosoma cruzi mismatch repair protein PMS1, putative 0.0012 0 0.0003
Toxoplasma gondii ATPase, AAA family protein 0.0014 0.0008 0.0031
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0035 0.0103 0.0192
Mycobacterium tuberculosis Conserved protein 0.0026 0.0061 0.009
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0105 0.0416 0.0416
Schistosoma mansoni heat shock protein 0.0167 0.0693 0.0918
Mycobacterium leprae Probable two component sensor kinase MprB 0.0026 0.0061 0.0126
Brugia malayi Calcitonin receptor-like protein seb-1 0.0231 0.0975 0.1814
Echinococcus granulosus intestinal type alkaline phosphatase 0.0104 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.002 0.0036 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0013 0.0021
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0053 0.0098
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0124 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0519 0.0687
Trypanosoma brucei hypothetical protein, conserved 0.0064 0.0231 0.1235
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0112 0.0112
Toxoplasma gondii microneme protein MIC17C 0.0015 0.0013 0.0055
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0272 0.1455
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.021 0.0885 0.1646
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.017 0.0707 0.1315
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.001 0.0052
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0496 0.2158 0.2857
Echinococcus multilocularis 6 phosphofructokinase 0.0281 0.1198 0.1198
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0128 0.0516 0.0959
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0009 0.0015
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.002 0.0036 0.0036
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0032 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.002 0.0032
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0037 0.0112 0.0112
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0059 0.0059
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.016 0.0261
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0035 0.0103 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0048 0.0257
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0031 0.0084 0.0111
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0124 0.0665
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0042 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0784 0.1038
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.137 0.732
Echinococcus multilocularis epidermal growth factor receptor 0.0175 0.0729 0.0729
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.006 0.0215 0.0285
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0049 0.0049
Echinococcus multilocularis epidermal growth factor receptor 0.0326 0.1398 0.1398
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Schistosoma mansoni tar DNA-binding protein 0.017 0.0707 0.0936
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0132 0.0534 0.2854
Trypanosoma cruzi heat shock protein 85, putative 0.0167 0.0693 0.3702
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.014 0.014
Onchocerca volvulus 0.006 0.0215 0.0352
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.014 0.014
Echinococcus multilocularis transcription factor eb 0.019 0.0792 0.0792
Echinococcus granulosus L aminoadipate semialdehyde 0.0227 0.0957 0.0957
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0022 0.0022
Echinococcus granulosus RUN 0.0013 0.0005 0.0005
Treponema pallidum 76K protein 0.0042 0.0134 0.0283
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0026 0.0061 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Trypanosoma brucei ornithine decarboxylase 0.0061 0.0219 0.1169
Schistosoma mansoni hypothetical protein 0.0035 0.0104 0.0138
Loa Loa (eye worm) heterochromatin protein 1 0.0085 0.0326 0.0607
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0022 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0784 0.1038
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0076 0.0285 0.1521
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0104 0.0412 0.0412
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0209 0.1118
Mycobacterium ulcerans hypothetical protein 0.0035 0.0103 0.086
Echinococcus multilocularis Niemann Pick C1 protein 0.0194 0.0811 0.0811
Schistosoma mansoni microrchidia 2a 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0042 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Plasmodium vivax basic transcription factor 3b, putative 0.0023 0.005 0.0207
Trypanosoma cruzi polo-like protein kinase, putative 0.0432 0.1872 1
Onchocerca volvulus 0.0061 0.0219 0.0357
Onchocerca volvulus 0.0042 0.0134 0.0219
Toxoplasma gondii pyruvate kinase PyKII 0.0024 0.0052 0.0216
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0176 0.0287
Echinococcus granulosus Polycystic kidney disease protein 0.0013 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0073 0.0272 0.0361
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0067 0.0247 0.0247
Loa Loa (eye worm) PHD-finger family protein 0.0015 0.0012 0.0023
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0104 0.0868
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0044 0.0142 0.0757
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Onchocerca volvulus 0.0025 0.0059 0.0097
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Brugia malayi nuclear receptor NHR-67 0.006 0.0215 0.0401
Schistosoma mansoni hypothetical protein 0.0025 0.0059 0.0078
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.0303 0.1618
Trichomonas vaginalis DNA helicase recq, putative 0.0036 0.0107 0.0174
Onchocerca volvulus 0.1386 0.6124 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0046 0.0152 0.0283
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.016 0.0324
Leishmania major DNA polymerase kappa, putative 0.0023 0.0048 0.0257
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.002 0.0036 0.0029
Brugia malayi Cation transporter family protein 0.0019 0.0032 0.0059
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0097 0.0378 0.0704
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0103 0.055
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0128 0.0516 0.0516
Loa Loa (eye worm) hypothetical protein 0.0106 0.0419 0.0779
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0124 0.0263
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Schistosoma mansoni nuclear receptor nhr-48 0.006 0.0215 0.0285
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0048 0.0064
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0059 0.0059
Leishmania major heat shock protein, putative 0.0105 0.0416 0.2224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0128 0.0516 0.0959
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0022 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0059 0.0078
Echinococcus multilocularis pyruvate kinase 0.0036 0.0109 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Echinococcus multilocularis serotonin receptor 0.0025 0.0059 0.0059
Leishmania major phosphopantetheinyl transferase-like protein 0.0064 0.0231 0.1235
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0025 0.0059 0.0059
Brugia malayi MAP kinase sur-1 0.0059 0.0209 0.0389
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Echinococcus multilocularis pyruvate kinase 0.0046 0.0152 0.0152
Schistosoma mansoni tyrosine kinase 0.0172 0.0716 0.0948
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.0589 0.078
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0124 0.0231
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0026 0.0061 0.0958
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0153
Loa Loa (eye worm) hypothetical protein 0.0158 0.0652 0.1212
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.006 0.0215 0.0401
Echinococcus multilocularis tar DNA binding protein 0.017 0.0707 0.0707
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0132 0.0534 0.2205
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0103 0.055
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0015 0.0013 0.0055
Brugia malayi G protein-coupled receptor 0.0025 0.0059 0.011
Schistosoma mansoni amyloid beta A4 protein related 0.0048 0.0162 0.0214
Echinococcus granulosus g-protein coupled receptor 0.0025 0.0059 0.0059
Entamoeba histolytica hypothetical protein 0.0144 0.0589 0.3148
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus granulosus g protein coupled receptor 0.0025 0.0059 0.0059
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0208
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.001 0.001
Brugia malayi Bloom's syndrome protein homolog 0.0055 0.019 0.0354
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0168 0.0899
Echinococcus multilocularis chromobox protein 2 0.0014 0.0009 0.0009
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0035 0.0103 0.0168
Schistosoma mansoni smad 0.0017 0.0022 0.0029
Echinococcus granulosus 6 phosphofructokinase 0.0281 0.1198 0.1198
Echinococcus granulosus expressed conserved protein 0.0127 0.0515 0.0515
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0867 0.3811 0.8978
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0189 0.0788 0.1467
Treponema pallidum NADH oxidase 0.0132 0.0534 0.1131
Loa Loa (eye worm) TOPoisomerase family member 0.0026 0.0061 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0128 0.0516 0.0959
Entamoeba histolytica hypothetical protein 0.0042 0.0134 0.0715
Entamoeba histolytica DNA topoisomerase II, putative 0.0026 0.0061 0.0326
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0272 0.1455
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0128 0.0516 0.0959
Echinococcus granulosus tachykinin peptides receptor 99D 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Toxoplasma gondii TIM10 family protein, putative 0.0031 0.0084 0.0345
Brugia malayi laminin alpha chain 0.0052 0.018 0.0334
Brugia malayi SET domain containing protein 0.0022 0.0043 0.008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0124 0.0513
Echinococcus multilocularis protein patched 0.0058 0.0206 0.0206
Echinococcus multilocularis smad 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0208
Trichomonas vaginalis pyruvate kinase, putative 0.0046 0.0152 0.0248
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.1048 0.1949
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0001 0.0001
Echinococcus granulosus fmrfamide receptor 0.0025 0.0059 0.0059
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0114 0.0454 0.0454
Trypanosoma brucei NADH dehydrogenase 0.0035 0.0103 0.055
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Mycobacterium ulcerans NADH dehydrogenase 0.0035 0.0103 0.086
Echinococcus granulosus nibrin 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.009 0.0167
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0105 0.0416 0.068
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0124 0.0662
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0104 0.0429
Loa Loa (eye worm) hypothetical protein 0.0027 0.0068 0.0126
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0029 0.0029
Trichomonas vaginalis ornithine decarboxylase, putative 0.0061 0.0219 0.0357
Loa Loa (eye worm) hypothetical protein 0.0022 0.0045 0.0083
Echinococcus multilocularis tumor protein p63 0.0723 0.317 0.317
Leishmania major mismatch repair protein, putative 0.0012 0 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0008 0.0041
Trypanosoma brucei heat shock protein 90, putative 0.0167 0.0693 0.3702
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0129 0.0523 0.0854
Brugia malayi Nuclear hormone receptor E75 0.006 0.0215 0.0401
Schistosoma mansoni DNA mismatch repair protein MLH1 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0085 0.0158
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0009 0.0038
Loa Loa (eye worm) ICD-1 protein 0.0023 0.005 0.0093
Toxoplasma gondii microneme protein MIC4 0.0015 0.0013 0.0055
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0272 0.0361
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0025 0.0059 0.011
Echinococcus granulosus endoplasmin 0.0154 0.0632 0.0632
Schistosoma mansoni chromobox protein 0.0085 0.0326 0.0432
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.006 0.0215 0.0285
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.002 0.0036 0.0297
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Echinococcus granulosus GPCR family 2 0.0073 0.0272 0.0272
Brugia malayi Cation transporter family protein 0.0019 0.0032 0.0059
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Loa Loa (eye worm) cytochrome P450 0.0035 0.0104 0.0193
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0272 0.1455
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.0589 0.0589
Brugia malayi Pyruvate kinase, muscle isozyme 0.0046 0.0152 0.0283
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.1048 0.1949
Mycobacterium ulcerans pyruvate kinase 0.0046 0.0152 0.1268
Schistosoma mansoni heat shock transcription factor 0.0015 0.0014 0.0019
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0036 0.019
Onchocerca volvulus 0.0019 0.0032 0.0052
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0064 0.0231 0.0493
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0247 0.046
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0168 0.0899
Schistosoma mansoni tyrosine kinase 0.0175 0.0729 0.0965
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0112 0.0148
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.003 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0064 0.0231 0.0954
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0112 0.0112
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0025 0.0059 0.0059
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0867 0.3811 0.8978
Schistosoma mansoni opsin-like receptor 0.0025 0.0059 0.0078
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0209 0.1118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0018 0.003
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0055 0.0192 0.0192
Plasmodium falciparum heterochromatin protein 1 0.0014 0.0009 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0026 0.0061 0.009
Giardia lamblia Heat shock protein HSP 90-alpha 0.0167 0.0693 0.37
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0132 0.0534 0.2854
Onchocerca volvulus 0.0025 0.0059 0.0097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi Dopamine receptor protein 1 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0084 0.0321 0.0598
Mycobacterium ulcerans acyl-CoA synthetase 0.0068 0.0248 0.2071
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0132 0.0534 0.4458
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni chromobox protein 0.0085 0.0326 0.0432
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0901 0.1471
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0032 0.0032
Brugia malayi hypothetical protein 0.0042 0.0134 0.0249
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0025 0.0059 0.011
Toxoplasma gondii 6-phosphofructokinase 0.0076 0.0285 0.1177
Entamoeba histolytica pyruvate kinase, putative 0.0032 0.009 0.0481
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0059 0.0059
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0035 0.0103 0.086
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0065 0.0236 0.1972
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0052
Schistosoma mansoni hypothetical protein 0.0056 0.0197 0.0261
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0067 0.0247 0.0247
Toxoplasma gondii diaminopimelate decarboxylase 0.0061 0.0219 0.0903
Brugia malayi Hsp90 protein 0.0105 0.0416 0.0774
Brugia malayi A-kinase anchor protein 10, precursor 0.0037 0.0112 0.0208
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0104 0.0868
Leishmania major DNA damage repair protein, putative 0.0023 0.0048 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0128 0.0516 0.0959
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0049 0.0049
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) nuclear hormone receptor 0.006 0.0215 0.0401
Loa Loa (eye worm) RNA binding protein 0.017 0.0707 0.1315
Schistosoma mansoni metabotropic glutamate receptor 0.0045 0.0148 0.0195
Echinococcus granulosus lamin 0.0065 0.0238 0.0238
Schistosoma mansoni myosin xvIII 0.0025 0.0059 0.0078
Schistosoma mansoni histamine h1 receptor 0.0025 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.005 0.0172 0.032
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0014 0.0008 0.0012
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0104 0.0868
Brugia malayi glutamate synthase 0.0035 0.0103 0.0192
Echinococcus granulosus tar DNA binding protein 0.017 0.0707 0.0707
Onchocerca volvulus 0.0065 0.0238 0.0389
Schistosoma mansoni cpg binding protein 0.0022 0.0046 0.0061
Brugia malayi polk-prov protein 0.0023 0.0048 0.009
Mycobacterium ulcerans monoxygenase 0.0035 0.0103 0.086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0158 0.065 0.1209
Mycobacterium ulcerans putative regultory protein 0.0026 0.0061 0.051
Schistosoma mansoni hypothetical protein 0.0012 0 0.0001
Brugia malayi DKFZp564C0469 protein 0.0014 0.0008 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0035 0.0103 0.1622
Echinococcus multilocularis dro:myosuppressin receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Trypanosoma brucei pyruvate kinase 1, putative 0.0046 0.0152 0.0812
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0025 0.0059 0.0059
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0025 0.0059 0.0059
Plasmodium falciparum glutathione reductase 0.038 0.1641 0.6773
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0053 0.0098
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0035 0.0103 0.055
Loa Loa (eye worm) flap endonuclease-1 0.0032 0.0089 0.0165
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) glutamate receptor 0.0036 0.0109 0.0203
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0059 0.0059
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0281 0.1198 0.2811
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0026 0.0061 0.0958
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0076 0.0285 0.1177
Mycobacterium ulcerans 6-phosphofructokinase 0.0281 0.1198 1
Schistosoma mansoni nuclear hormone receptor 0.006 0.0215 0.0285
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0026 0.0061 0.051
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0055 0.0192 0.1024
Schistosoma mansoni hypothetical protein 0.0021 0.0042 0.0056
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.002 0.002
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0009 0.0017
Schistosoma mansoni smad1 5 8 and 0.0017 0.0022 0.0029
Schistosoma mansoni SET domain protein 0.0017 0.0023 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1218 0.5375 1
Trichomonas vaginalis hypothetical protein 0.0014 0.0009 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0048 0.0257
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0035 0.0103 0.0103
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0026 0.0061 0.01
Plasmodium vivax pyruvate kinase, putative 0.0046 0.0152 0.0627
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0059 0.0078
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0029 0.0029
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0188 0.0784 0.1459
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0104 0.0191
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0035 0.0103 0.086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0086 0.0161
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0036 0.0297
Loa Loa (eye worm) TYRA-2 protein 0.0025 0.0059 0.011
Plasmodium vivax ferrodoxin reductase, putative 0.0035 0.0103 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0048 0.0257
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0032 0.0059
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0026 0.0061 0.0061
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Entamoeba histolytica heat shock transcription factor, putative 0.0015 0.0014 0.0076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Echinococcus multilocularis endoplasmin 0.0154 0.0632 0.0632
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0026 0.0061 0.0061
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0281 0.1198 0.6402
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0025 0.006 0.006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.008 0.0303 0.0303
Echinococcus granulosus fetal alzheimer antigen falz 0.0017 0.0023 0.0023
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0025 0.0059 0.0059
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0026 0.0061 0.009
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0012 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0059 0.0059
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Schistosoma mansoni 6-phosphofructokinase 0.0281 0.1198 0.1587
Onchocerca volvulus 0.0025 0.0059 0.0097
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0168 0.0696 0.0696
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0132 0.0534 0.2205
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0029 0.0156
Mycobacterium ulcerans dehydrogenase 0.0035 0.0103 0.086
Brugia malayi hypothetical protein 0.0067 0.0247 0.046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0146 0.0598 0.3197
Loa Loa (eye worm) hypothetical protein 0.0068 0.0248 0.0462
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0153
Echinococcus multilocularis nuclear receptor nhr 48 0.006 0.0215 0.0215
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0132 0.0534 0.0534
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0104 0.0868
Onchocerca volvulus 0.002 0.0035 0.0057
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Onchocerca volvulus 0.0384 0.1659 0.2709
Echinococcus multilocularis heat shock protein 0.0167 0.0693 0.0693
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0104 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0104 0.0191
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.002 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Echinococcus multilocularis transcription factor Dp 1 0.0085 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0104 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0128 0.0516 0.0959
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0037 0.0111 0.0927
Echinococcus multilocularis somatostatin receptor 0.0025 0.0059 0.0059
Echinococcus granulosus neuropeptide FF receptor 2 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0063 0.0116
Schistosoma mansoni topbp1 0.0014 0.0008 0.001
Schistosoma mansoni alkaline phosphatase 0.0104 0.0412 0.0546
Schistosoma mansoni alkaline phosphatase 0.0104 0.0412 0.0546
Loa Loa (eye worm) TAR-binding protein 0.017 0.0707 0.1315
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Schistosoma mansoni intermediate filament proteins 0.0065 0.0238 0.0316
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0154 0.0632 0.1444
Echinococcus multilocularis sex peptide receptor 0.0025 0.0059 0.0059
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0036 0.019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0132 0.0534 0.0707
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.006 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0052 0.018 0.0334
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0026 0.0063 0.026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0052 0.018 0.0238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0215 0.0215
Toxoplasma gondii propionate-CoA ligase 0.002 0.0036 0.0147
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0076 0.0285 0.5334
Echinococcus multilocularis tyrosine protein kinase shark 0.0174 0.0723 0.0723
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0168 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0192 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0068 0.0248 0.0462
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Mycobacterium tuberculosis Possible two component sensor kinase 0.0026 0.0061 0.009
Echinococcus multilocularis pyruvate kinase 0.0046 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Echinococcus granulosus sex peptide receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Echinococcus granulosus geminin 0.0651 0.2847 0.2847
Entamoeba histolytica hypothetical protein 0.0144 0.0589 0.3148
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0067 0.0247 0.0247
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0132 0.0534 0.2854
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0005 0.0005
Schistosoma mansoni endoplasmin 0.0167 0.0693 0.0918
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0272 0.0361
Schistosoma mansoni tyrosine kinase 0.0172 0.0716 0.0948
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0009 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.016 0.0261
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.002 0.0036 0.0147
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0009 0.0038
Schistosoma mansoni hypothetical protein 0.0023 0.0049 0.0065
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0209 0.0209
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni DNA ligase IV 0.0014 0.0008 0.001
Brugia malayi RNA binding protein 0.017 0.0707 0.1315
Brugia malayi CHD4 protein 0.0016 0.002 0.0038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0059 0.0059
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0124 0.0124
Plasmodium falciparum LCCL domain-containing protein 0.0013 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0052 0.018 0.0334
Toxoplasma gondii heat shock protein HSP90 0.0167 0.0693 0.286
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0964 0.4243 1
Toxoplasma gondii hypothetical protein 0.0015 0.0013 0.0055
Echinococcus granulosus Chromobox protein 3 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0238 0.0444
Entamoeba histolytica recQ family helicase, putative 0.0036 0.0107 0.0569
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0061 0.01
Schistosoma mansoni hypothetical protein 0.0158 0.065 0.086
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0032 0.0059
Mycobacterium ulcerans two component regulator - sensor kinase 0.0026 0.0061 0.051
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.002 0.0036 0.0297
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0146 0.0598 0.3197
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Schistosoma mansoni nuclear receptor 0.006 0.0215 0.0285
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.001 0.0052
Brugia malayi Heterochromatin protein 1 0.0085 0.0326 0.0607
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.002 0.0036 0.019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni coup transcription factor 0.0128 0.0516 0.0683
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Loa Loa (eye worm) hypothetical protein 0.024 0.1016 0.189
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.014 0.014
Brugia malayi Cytochrome P450 family protein 0.0065 0.0236 0.044
Leishmania major mismatch repair protein PMS1, putative,mismatch repair protein 0.0012 0 0.0003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.006 0.0215 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Brugia malayi larval opioid receptor 0.0025 0.0059 0.011
Leishmania major 4-coumarate:coa ligase-like protein 0.0068 0.0248 0.1326
Trypanosoma brucei cytochrome P450, putative 0.0065 0.0236 0.1262
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0192
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0059 0.0059
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0035 0.0103 0.0425
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0055 0.0192 0.1024
Plasmodium falciparum DNA topoisomerase 2 0.0026 0.0061 0.0252
Brugia malayi PHD-finger family protein 0.0019 0.0031 0.0057
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.002 0.0036 0.0147
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.002 0.0036 0.0297
Plasmodium falciparum endoplasmin, putative 0.0119 0.0477 0.1968
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.002 0.0036 0.019
Brugia malayi chromobox protein homolog 3 0.0048 0.016 0.0297
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0032 0.0032
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0026 0.0061 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.012 0.0159
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0026 0.0061 0.0252
Entamoeba histolytica ornithine decarboxylase, putative 0.0061 0.0219 0.1169
Trypanosoma brucei PAB1-binding protein , putative 0.0047 0.0159 0.0847
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0009 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0012 0.0001 0.0001
Trypanosoma brucei trypanothione reductase 0.038 0.1641 0.8768
Echinococcus multilocularis sterol regulatory element binding protein 0.0058 0.0206 0.0206
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0059 0.0078
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0014 0.0008 0.0014
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0128 0.0516 0.0683
Echinococcus multilocularis FTZ F1 alpha 0.0128 0.0516 0.0516
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0128 0.0516 0.0959
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0026 0.0061 0.051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0026 0.0061 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Schistosoma mansoni amine GPCR 0.0025 0.0059 0.0078
Brugia malayi Pyridoxal-dependent decarboxylase, pyridoxal binding domain containing protein 0.0061 0.0219 0.0407
Plasmodium falciparum basic transcription factor 3b, putative 0.0023 0.005 0.0207
Trichomonas vaginalis glutamate synthase, putative 0.0035 0.0103 0.0168
Leishmania major cytochrome p450-like protein 0.0035 0.0104 0.0556
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0042 0.0134 0.0249
Schistosoma mansoni lipoxygenase 0.0055 0.019 0.0252
Giardia lamblia Glutamate synthase 0.0035 0.0103 0.0548
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0042 0.0134 0.0249
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0104 0.0868
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0061 0.0252
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0146 0.0598 0.1113
Brugia malayi MH2 domain containing protein 0.0247 0.1048 0.1949
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0035 0.0103 0.0225
Mycobacterium ulcerans hypothetical protein 0.0068 0.0248 0.2071
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.012 0.0224
Plasmodium vivax flap endonuclease 1, putative 0.0032 0.0089 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0092 0.015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0128 0.0516 0.0683
Trypanosoma cruzi polo-like protein kinase, putative 0.0432 0.1872 1
Loa Loa (eye worm) heat shock protein 90 0.0167 0.0693 0.1289
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0128 0.0516 0.0516
Plasmodium vivax acyl-CoA synthetase, putative 0.005 0.0172 0.071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Brugia malayi Serotonin receptor 0.0025 0.0059 0.011
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0064 0.0231 0.3651
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0132 0.0534 0.2854
Loa Loa (eye worm) doublecortin family protein 0.0013 0.0005 0.001
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0061 0.0326
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0032 0.0032
Schistosoma mansoni neuropeptide f receptor 76f 0.0025 0.0059 0.0078
Trichomonas vaginalis DNA topoisomerase II, putative 0.0026 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.0294 0.1258 0.2341
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0041 0.013 0.0693
Loa Loa (eye worm) latrophilin receptor protein 2 0.0073 0.0272 0.0507
Schistosoma mansoni nuclear hormone receptor 0.0128 0.0516 0.0683
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0208
Giardia lamblia NADH oxidase lateral transfer candidate 0.0132 0.0534 0.2852
Toxoplasma gondii microneme protein, putative 0.0015 0.0013 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0128 0.0516 0.0959
Onchocerca volvulus 0.0014 0.0009 0.0015
Echinococcus granulosus alpha 1A adrenergic receptor 0.0025 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Loa Loa (eye worm) CUTiclin family member 0.0042 0.0134 0.0249
Brugia malayi RNA recognition motif domain containing protein 0.017 0.0707 0.1315
Echinococcus multilocularis 0.0035 0.0104 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0013 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0059 0.011
Brugia malayi hypothetical protein 0.0014 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0076 0.0285 0.5334
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Echinococcus granulosus expressed protein 0.0719 0.3152 0.3152
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0048 0.0257
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0026 0.0061 0.0126
Onchocerca volvulus 0.021 0.0885 0.1444
Echinococcus granulosus lamin dm0 0.0065 0.0238 0.0238
Echinococcus granulosus Niemann Pick C1 protein 0.0194 0.0811 0.0811
Onchocerca volvulus 0.0042 0.0134 0.0219
Schistosoma mansoni adenoreceptor 0.0025 0.0059 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Entamoeba histolytica hypothetical protein 0.0014 0.0009 0.0049
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0215 0.0352
Leishmania major DNA polymerase eta, putative 0.0023 0.0048 0.0257
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0176 0.073 0.073
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0272 0.2273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0192 0.0313
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0268
Treponema pallidum hypothetical protein 0.0042 0.0134 0.0283
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0209 0.0342
Loa Loa (eye worm) glutamate receptor 0.0092 0.0358 0.0667
Leishmania major DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Leishmania major hypothetical protein, conserved 0.0027 0.0067 0.0357
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0112 0.0148
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Plasmodium falciparum thrombospondin-related anonymous protein 0.0042 0.0134 0.0552
Leishmania major 4-coumarate:coa ligase-like protein 0.0068 0.0248 0.1326
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0026 0.0061 0.051
Leishmania major DNA polymerase eta, putative 0.0073 0.0272 0.1455
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.014 0.014
Brugia malayi Metabotropic glutamate receptor precursor. 0.0092 0.0358 0.0667
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0032 0.0059
Entamoeba histolytica Flap nuclease, putative 0.0032 0.0089 0.0474
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.0192 0.0356
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0032 0.0032
Echinococcus multilocularis pyruvate kinase 0.0024 0.0052 0.0052
Leishmania major NADH dehydrogenase, putative 0.0035 0.0103 0.055
Echinococcus multilocularis RUN 0.0013 0.0005 0.0005
Onchocerca volvulus 0.0023 0.0048 0.0078
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0124 0.0124
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.0303 0.1618
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0176 0.073 0.3014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0519 0.0687
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0168 0.0168
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0014 0.0008 0.0012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0964 0.4243 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0085 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.0128 0.0516 0.0516
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.0763 0.4076
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0026 0.0061 0.0326
Schistosoma mansoni disulfide oxidoreductase 0.0035 0.0103 0.0136
Echinococcus multilocularis G protein coupled receptor 139 0.0025 0.0059 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Echinococcus granulosus g protein coupled receptor 0.0025 0.0059 0.0059
Echinococcus granulosus voltage dependent calcium channel 0.0067 0.0247 0.0247
Loa Loa (eye worm) helicase 0.0014 0.0009 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0068 0.0248 0.1326
Echinococcus granulosus pyruvate kinase 0.0024 0.0052 0.0052
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0022 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0763 0.6367
Brugia malayi putative neuropeptide receptor NPR1 0.0025 0.0059 0.011
Trypanosoma cruzi Heat shock protein 83, putative 0.0167 0.0693 0.3702
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0035 0.0103 0.0103
Schistosoma mansoni Smad4 0.0017 0.0022 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0124 0.024
Echinococcus multilocularis lamin dm0 0.0065 0.0238 0.0238
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Toxoplasma gondii hypothetical protein 0.0012 0.0002 0.001
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0176 0.0287
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0055 0.0192 0.0192
Echinococcus granulosus insulin receptor 0.0105 0.0414 0.0414
Schistosoma mansoni hypothetical protein 0.0042 0.0134 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0128 0.0516 0.0516
Trichomonas vaginalis pyridoxal-dependent decarboxylase, putative 0.0061 0.0219 0.0357
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0035 0.0103 0.086
Schistosoma mansoni amine GPCR 0.0025 0.0059 0.0078
Leishmania major DNA topoisomerase ii 0.0026 0.0061 0.0326
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Giardia lamblia DNA damage repair protein 0.0023 0.0048 0.0254
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0247 0.046
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0128 0.0519 0.0965
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0035 0.0103 0.055
Schistosoma mansoni bromodomain containing protein 0.0046 0.0151 0.02
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0014 0.0008 0.0063
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0231 0.0975 0.1814
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0073 0.0272 0.0272
Schistosoma mansoni voltage-gated cation channel 0.0067 0.0247 0.0327
Brugia malayi AMP-binding enzyme family protein 0.002 0.0036 0.0066
Giardia lamblia Grp94/Hsp90 0.0154 0.0632 0.3377
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0059 0.0059
Echinococcus granulosus epidermal growth factor receptor 0.0326 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0031 0.0085 0.0158
Brugia malayi hypothetical protein 0.0047 0.0159 0.0295
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0132 0.0534 0.8446
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0085 0.0158
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.014 0.0261
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0032 0.0059
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.0763 0.0763
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0104 0.0191
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0026 0.0063 0.0335
Onchocerca volvulus 0.0023 0.0049 0.0081
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0013 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Loa Loa (eye worm) cytochrome P450 family protein 0.0117 0.0468 0.087
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0035 0.0103 0.0425
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0132 0.0534 0.2854
Echinococcus granulosus citrate lyase subunit beta protein 0.0037 0.0111 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0103 0.055
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0032 0.0089 0.0474
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Schistosoma mansoni tyrosine kinase 0.0172 0.0716 0.0948
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0112 0.0148
Onchocerca volvulus 0.0015 0.0013 0.0022
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Onchocerca volvulus 0.0053 0.0182 0.0297
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0014 0.0008 0.0012
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0037 0.0112 0.0148
Echinococcus granulosus mixed lineage leukemia protein mll 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.002 0.0036 0.0066
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0223 0.0942 0.0942
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0032 0.0059
Echinococcus granulosus dna polymerase eta 0.0073 0.0272 0.0272
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0064 0.0231 0.4322
Brugia malayi latrophilin 2 splice variant baaae 0.0158 0.065 0.1209
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0029 0.0156
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0022 0.0022
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.002 0.0036 0.0297
Loa Loa (eye worm) X11 protein 0.0048 0.0162 0.0301
Brugia malayi Furin-like cysteine rich region family protein 0.0326 0.1398 0.2601
Onchocerca volvulus 0.0015 0.0013 0.0022
Brugia malayi Protein kinase domain containing protein 0.0026 0.0063 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0012
Echinococcus granulosus Chromo domain 0.0014 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0303 0.0494
Echinococcus granulosus muscleblind protein 0.0096 0.0374 0.0374
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Schistosoma mansoni cpg binding protein 0.002 0.0035 0.0046
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0035 0.0103 0.0168
Echinococcus multilocularis ecdysone induced protein 78C 0.0128 0.0516 0.0516
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0084 0.032 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0916
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0025 0.0059 0.0078
Mycobacterium ulcerans hypothetical protein 0.0022 0.0045 0.0374
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0085 0.0085
Schistosoma mansoni sulfide quinone reductase 0.0035 0.0103 0.0136
Entamoeba histolytica DNA mismatch repair protein MLH1, putative 0.0012 0 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0025 0.0059 0.011
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0049 0.0204
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0867 0.3811 0.8978
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0166 0.0219
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0432 0.1872 0.3483
Onchocerca volvulus 0.0019 0.0032 0.0052
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0035 0.0103 0.0425
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Onchocerca volvulus 0.0068 0.0248 0.0405
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0281 0.1198 0.2785
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0117
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0014 0.0012 0.0012
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Trypanosoma cruzi FHA domain containing protein, putative 0.0014 0.0008 0.0041
Echinococcus granulosus pyruvate kinase 0.0024 0.0052 0.0052
Brugia malayi Melatonin receptor type 1A 0.0025 0.0059 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0128 0.0516 0.0516
Schistosoma mansoni hypothetical protein 0.0024 0.0053 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.012 0.0159
Plasmodium vivax 6-phosphofructokinase, putative 0.0076 0.0285 0.1177
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0027 0.0067 0.0357
Trichomonas vaginalis set domain proteins, putative 0.1386 0.6124 1
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0042 0.0134 0.0552
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0085 0.0349
Onchocerca volvulus Protein ultraspiracle homolog 0.0128 0.0516 0.0842
Echinococcus granulosus microtubule associated protein 2 0.1706 0.7552 0.7552
Plasmodium vivax DNA mismatch repair protein PMS1, putative 0.0012 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) thioredoxin reductase 0.038 0.1641 0.3054
Trichomonas vaginalis hypothetical protein 0.0041 0.0129 0.0211
Trypanosoma cruzi mismatch repair protein MLH1, putative 0.0012 0 0.0003
Schistosoma mansoni glutamate synthase 0.0035 0.0103 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0032 0.0088 0.0088
Schistosoma mansoni regulator of G protein signaling 0.0043 0.014 0.0186
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0025 0.0059 0.011
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0175 0.0729 0.0729
Toxoplasma gondii selenide, water dikinase 0.0035 0.0103 0.0425
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0059 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0104 0.0191
Brugia malayi Intermediate filament tail domain containing protein 0.0065 0.0238 0.0444
Mycobacterium ulcerans glutamate synthase subunit beta 0.0035 0.0103 0.086
Leishmania major hypothetical protein, conserved 0.0035 0.0103 0.055
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0037 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.005 0.017 0.0316
Treponema pallidum oxidoreductase 0.0035 0.0103 0.0217
Brugia malayi nuclear hormone receptor family member odr-7 0.006 0.0215 0.0401
Trypanosoma cruzi NADH dehydrogenase, putative 0.0035 0.0103 0.055
Schistosoma mansoni hypothetical protein 0.0056 0.0197 0.0261
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0009 0.0009
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0128 0.0516 0.0683
Echinococcus granulosus sterol regulatory element binding protein 0.0058 0.0206 0.0206
Brugia malayi Cytochrome P450 family protein 0.0065 0.0236 0.044
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0016 0.002 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Brugia malayi AMP-binding enzyme family protein 0.002 0.0036 0.0066
Echinococcus granulosus pikachurin 0.0052 0.018 0.018
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0104 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0152
Mycobacterium tuberculosis Diaminopimelate decarboxylase LysA (DAP decarboxylase) 0.0061 0.0219 0.0463
Echinococcus multilocularis allatostatin A receptor 0.0025 0.0059 0.0059
Trypanosoma cruzi mismatch repair protein MLH1, putative 0.0012 0 0.0003
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1026 0.4519 0.4519
Loa Loa (eye worm) voltage-dependent calcium channel 0.0014 0.001 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0068 0.0248 0.0462
Brugia malayi DNA mismatch repair protein MutL containing protein 0.0012 0 0.0001
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0048 0.0257
Schistosoma mansoni neuropeptide receptor 0.0025 0.0059 0.0078
Brugia malayi hypothetical protein 0.0013 0.0005 0.001
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0064 0.0231 0.1929
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0067 0.0247 0.0247
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0061 0.0219 0.0903
Onchocerca volvulus 0.002 0.0036 0.0058
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.006 0.0215 0.0215
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0138 0.0561 0.0743
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0025 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0035 0.0103 0.0136
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0025 0.0059 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0916
Toxoplasma gondii PAN/Apple domain-containing protein 0.0015 0.0013 0.0055
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0272 0.059
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0134 0.0715
Brugia malayi topoisomerase 0.0014 0.0008 0.0014
Onchocerca volvulus 0.0015 0.0013 0.0022
Loa Loa (eye worm) pyruvate kinase 0.0046 0.0152 0.0283
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0025 0.006 0.006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0035 0.0103 0.0192
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.0763 0.3149
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0035 0.0103 0.086
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0146 0.0598 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0901 0.1471
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0223 0.0942 0.1752
Loa Loa (eye worm) PXA domain-containing protein 0.0037 0.0112 0.0208
Plasmodium vivax glutathione reductase, putative 0.038 0.1641 0.6773
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0026 0.0061 0.009
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0009 0.0038
Plasmodium vivax heterochromatin protein 1, putative 0.0014 0.0009 0.0038
Brugia malayi Thioredoxin reductase 0.038 0.1641 0.3054
Plasmodium vivax heat shock protein, putative 0.0556 0.2423 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0112 0.0148
Brugia malayi MH1 domain containing protein 0.0017 0.0022 0.0041
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0026 0.0061 0.009
Echinococcus granulosus FTZ F1 alpha 0.0128 0.0516 0.0516
Onchocerca volvulus 0.0015 0.0013 0.0022
Onchocerca volvulus 0.0025 0.0059 0.0097
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0209 0.1116
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0016
Echinococcus multilocularis L aminoadipate semialdehyde 0.0227 0.0957 0.0957
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.1872 0.2479
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0026 0.0061 0.051
Brugia malayi CHE-14 protein 0.0058 0.0206 0.0384
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.002 0.0027
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0032 0.0059
Giardia lamblia Pms1-like protein 0.0026 0.0061 0.0324
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0015 0.0078
Toxoplasma gondii endonuclease IV APN 0.0083 0.0318 0.1314
Echinococcus granulosus X box binding protein 1 0.0191 0.0796 0.0796
Schistosoma mansoni cell polarity protein 0.0052 0.018 0.0238
Brugia malayi ORL1-like opioid receptor 0.0025 0.0059 0.011
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0104 0.0191
Schistosoma mansoni slit 0.0052 0.018 0.0238
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0041 0.013 0.0693
Brugia malayi metabotropic glutamate receptor type 2 0.0045 0.0148 0.0275
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0035 0.0103 0.0425
Schistosoma mansoni opsin-like receptor 0.0025 0.0059 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Echinococcus granulosus ubiquitin specific protease 41 0.008 0.0303 0.0303
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0035 0.0103 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Schistosoma mansoni axis inhibition protein axin 0.0037 0.0112 0.0148
Loa Loa (eye worm) pyruvate kinase 0.0046 0.0152 0.0283
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0061 0.0326
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Echinococcus multilocularis nAChR subunit 0.0019 0.0032 0.0032
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Leishmania major trypanothione reductase 0.038 0.1641 0.8768
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0209 0.0342
Plasmodium vivax DNA topoisomerase II, putative 0.0026 0.0061 0.0252
Echinococcus granulosus thyroid hormone receptor alpha 0.006 0.0215 0.0215
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0049 0.0204
Trichomonas vaginalis heat shock protein, putative 0.0093 0.0363 0.0593
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.012 0.012
Brugia malayi conserved hypotetical protein 0.006 0.0215 0.0401
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0107 0.0569
Leishmania major hypothetical protein, conserved 0.0026 0.0061 0.0326
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.002 0.0036 0.0297
Schistosoma mansoni biogenic amine receptor 0.0025 0.0059 0.0078
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.012 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0176 0.073 0.0967
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Brugia malayi hypothetical protein 0.0037 0.0112 0.0208
Toxoplasma gondii DNA topoisomerase 2, putative 0.0026 0.0061 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Brugia malayi HSF-type DNA-binding domain containing protein 0.024 0.1016 0.189
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0036 0.0029
Entamoeba histolytica heat shock transcription factor, putative 0.0015 0.0014 0.0076
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Echinococcus granulosus axis inhibition protein axin 0.0037 0.0112 0.0112
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0031 0.0084 0.0156
Trypanosoma brucei unspecified product 0.005 0.0171 0.0916
Loa Loa (eye worm) bromodomain containing protein 0.0012 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) melatonin receptor type 1A 0.0025 0.0059 0.011
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0073 0.0272 0.059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0019
Echinococcus granulosus dna polymerase kappa 0.0073 0.0272 0.0272
Schistosoma mansoni pyruvate dehydrogenase 0.0026 0.0061 0.0081
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2255 1 1
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0007
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0104 0.0556
Entamoeba histolytica acyl-coA synthetase, putative 0.0068 0.0248 0.1326
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Brugia malayi Serotonin receptor 0.0025 0.0059 0.011
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0105 0.0414 0.0414
Brugia malayi hypothetical protein 0.006 0.0215 0.0401
Trypanosoma cruzi transcription factor btf3, putative 0.0023 0.005 0.0268
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0132 0.0534 0.2854
Schistosoma mansoni DNA mismatch repair protein PMS2 0.0012 0 0.0001
Mycobacterium leprae Probable pyruvate kinase PykA 0.0046 0.0152 0.0341
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0104 0.0412 0.0412
Schistosoma mansoni tar DNA-binding protein 0.017 0.0707 0.0936
Echinococcus multilocularis geminin 0.0651 0.2847 0.2847
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0025 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.001 0.0041
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.038 0.1641 0.3835
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0035 0.0103 0.0103
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0032 0.0032
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0055 0.0192 0.1024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0068 0.0248 0.0533
Echinococcus granulosus allatostatin A receptor 0.0025 0.0059 0.0059
Schistosoma mansoni tar DNA-binding protein 0.017 0.0707 0.0936
Brugia malayi nuclear receptor RXR 0.006 0.0215 0.0401
Plasmodium falciparum heat shock protein 90, putative 0.0556 0.2423 1
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0026 0.0061 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0093 0.0152
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0168 0.0899
Schistosoma mansoni SET domain protein 0.003 0.0082 0.0109
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0061 0.1135
Entamoeba histolytica phosphofructokinase, putative 0.0281 0.1198 0.6402
Loa Loa (eye worm) hypothetical protein 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.0192 0.0356
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Plasmodium vivax replication factor C subunit 1, putative 0.0014 0.0008 0.0031
Plasmodium falciparum thioredoxin reductase 0.0132 0.0534 0.2205
Onchocerca volvulus 0.0015 0.0013 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0236 0.044
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0032 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0272 0.0507
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0551 0.0551
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0009 0.0017
Schistosoma mansoni glutamate synthase 0.0035 0.0103 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0209 0.0342
Onchocerca volvulus 0.0042 0.0134 0.0219
Mycobacterium ulcerans DNA gyrase subunit B 0.0026 0.0061 0.051
Loa Loa (eye worm) 6-phosphofructokinase 0.0281 0.1198 0.2229
Echinococcus granulosus slit 2 protein 0.0052 0.018 0.018
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0061 0.0252
Trypanosoma cruzi pyruvate kinase 2, putative 0.0046 0.0152 0.0812
Schistosoma mansoni endoplasmin 0.0167 0.0693 0.0918
Chlamydia trachomatis thioredoxin reductase 0.0035 0.0103 0.1921
Entamoeba histolytica hypothetical protein 0.0014 0.0008 0.0041
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Echinococcus multilocularis neuropeptide FF receptor 2 0.0025 0.0059 0.0059
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0126 0.0508 0.0508
Loa Loa (eye worm) TK/INSR protein kinase 0.0105 0.0414 0.0771
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0916
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Echinococcus multilocularis survival motor neuron protein 1 0.1031 0.4543 0.4543
Echinococcus granulosus 7tm_1 domain containing protein 0.0025 0.0059 0.0059
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0084 0.0321 0.0321
Brugia malayi hypothetical protein 0.0046 0.0153 0.0285
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0035 0.0101 0.0417
Trypanosoma cruzi pyruvate kinase 2, putative 0.0046 0.0152 0.0812
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0085 0.0349
Brugia malayi nuclear hormone receptor 0.006 0.0215 0.0401
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0134 0.0552
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1821 0.8064 0.8064
Schistosoma mansoni tsg101-related 0.007 0.0259 0.0343
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0061 0.0252
Loa Loa (eye worm) heat shock protein 75 0.0105 0.0416 0.0774
Echinococcus granulosus glutamate synthase 0.0035 0.0103 0.0103
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0073 0.0272 0.0272
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0036 0.0029
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0026 0.0061 0.051
Brugia malayi Dopamine receptor protein 2 0.0025 0.0059 0.011
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0037 0.0111 0.0593
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0059 0.0059
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0014 0.0008 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Brugia malayi isocitrate dehydrogenase 0.005 0.0168 0.0313
Loa Loa (eye worm) Smad1 0.0017 0.0022 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Schistosoma mansoni smad1 5 8 and 0.0017 0.0022 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0078 0.0295 0.0295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0059 0.0078
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0026 0.0061 0.009
Brugia malayi EGF-like domain containing protein 0.0052 0.018 0.0334
Onchocerca volvulus 0.0015 0.0013 0.0022
Schistosoma mansoni tyrosine kinase 0.0326 0.1398 0.1851
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0373 0.1611 0.2997
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0128 0.0516 0.0959
Echinococcus multilocularis heat shock protein 90 0.0167 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0068 0.0248 0.0462
Trichomonas vaginalis diaminopimelate decarboxylase, putative 0.0061 0.0219 0.0357
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0032 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0128 0.0516 0.0959
Schistosoma mansoni opsin-like receptor 0.0025 0.0059 0.0078
Echinococcus multilocularis Polycystic kidney disease protein 0.0013 0.0005 0.0005
Schistosoma mansoni tsg101-related 0.0057 0.0202 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Echinococcus multilocularis chromobox protein 1 0.0085 0.0326 0.0326
Onchocerca volvulus 0.0015 0.0013 0.0022
Toxoplasma gondii DNA mismatch repair protein, C-terminal domain-containing protein 0.0012 0 0.0002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.008 0.0303 0.0303
Onchocerca volvulus 0.002 0.0036 0.0058
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0168 0.0899
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0017 0.0023
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0035 0.0103 0.0168
Echinococcus multilocularis musashi 0.0065 0.0238 0.0238
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0026 0.0061 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.0763 0.1753
Brugia malayi Nuclear hormone receptor-like 1 0.0128 0.0516 0.0959
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0104 0.0191
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0061 0.0326
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0009 0.0009
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0026 0.0061 0.009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0029 0.0048
Schistosoma mansoni heat shock transcription factor 0.0015 0.0014 0.0019
Plasmodium vivax 6-phosphofructokinase, putative 0.0076 0.0285 0.1177
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0036 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0209 0.0342
Loa Loa (eye worm) hypothetical protein 0.0114 0.0454 0.0844
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0068 0.0248 0.2071
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0104 0.0104
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0015 0.0015 0.006
Onchocerca volvulus 0.0037 0.0114 0.0186
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0026 0.0061 0.0252
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi Regulator of G protein signaling domain containing protein 0.0037 0.0112 0.0208
Trichomonas vaginalis glutaminase, putative 0.0215 0.0904 0.1475
Toxoplasma gondii microneme protein MIC17A 0.0015 0.0013 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0012 0.0023
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0078 0.0295 0.0295
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.012 0.012
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0013 0.0025
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0035 0.0103 0.055
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0168 0.0168
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0025 0.0059 0.0078
Trypanosoma brucei Heat shock protein 83, putative 0.0167 0.0693 0.3702
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.002 0.0036 0.0029
Brugia malayi MH2 domain containing protein 0.0017 0.0022 0.0041
Brugia malayi cytochrome P450 0.0035 0.0104 0.0193
Echinococcus multilocularis Smad4 0.0017 0.0022 0.0022
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.003 0.0082 0.0082
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0009 0.0015
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0104 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0082
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0163
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0055 0.0192 0.1024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.008 0.0303 0.1618
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0132 0.0534 0.0994
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.107 0.4718 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0037 0.0112 0.0112
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0026 0.0061 0.051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0032 0.0032
Trypanosoma brucei protein kinase, putative 0.0059 0.0209 0.1118
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0176 0.0287
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0035 0.0103 0.055
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.005 0.0172 0.0353
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0035 0.0103 0.0225
Loa Loa (eye worm) hypothetical protein 0.0073 0.0272 0.0507
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0432 0.1872 0.1872
Trichomonas vaginalis glutathione reductase, putative 0.0132 0.0534 0.0872
Plasmodium vivax DNA mismatch repair protein MLH, putative 0.0012 0 0.0002
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Toxoplasma gondii LsmAD domain-containing protein 0.0047 0.0159 0.0654
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0014 0.0008 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.016 0.0324
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0148
Trichomonas vaginalis endoplasmin, putative 0.0119 0.0477 0.0779
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0168 0.0694
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Onchocerca volvulus 0.0025 0.0059 0.0097
Brugia malayi serine/threonine-protein kinase plk-2 0.0432 0.1872 0.3483
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Schistosoma mansoni nuclear hormone receptor 0.006 0.0215 0.0285
Echinococcus granulosus heat shock protein 90 0.0167 0.0693 0.0693
Echinococcus granulosus neurogenic locus notch protein 0.0052 0.018 0.018
Echinococcus multilocularis expressed conserved protein 0.0127 0.0515 0.0515
Onchocerca volvulus 0.0128 0.0516 0.0842
Schistosoma mansoni hypothetical protein 0.0042 0.0134 0.0177
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0026 0.0063 0.026
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0009 0.0015
Leishmania major cytochrome p450-like protein 0.0065 0.0236 0.1262
Mycobacterium ulcerans diaminopimelate decarboxylase LysA 0.0061 0.0219 0.1825
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0029 0.0039
Mycobacterium tuberculosis Probable reductase 0.0867 0.3811 0.8978
Toxoplasma gondii heat shock protein 90, putative 0.0167 0.0693 0.286
Brugia malayi AKH receptor 0.0025 0.0059 0.011
Brugia malayi nuclear receptor NHR-88 0.006 0.0215 0.0401
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0104 0.0412 0.0412
Mycobacterium ulcerans glutaminase 0.0215 0.0904 0.7541
Echinococcus multilocularis voltage dependent calcium channel 0.0067 0.0247 0.0247
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0168 0.0168
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0032 0.0042
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0032 0.0059
Echinococcus granulosus cpg binding protein 0.0022 0.0046 0.0046
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0026 0.0061 0.0061
Entamoeba histolytica transcription factor BTF3, putative 0.0023 0.005 0.0268
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0551 0.0551
Echinococcus granulosus epidermal growth factor receptor 0.0175 0.0729 0.0729
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0059 0.0059
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.012 0.0224
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0032 0.0059
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Echinococcus granulosus amyloid beta A4 protein 0.0048 0.0162 0.0162
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0067 0.0247 0.0328
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0209 0.0389
Loa Loa (eye worm) hypothetical protein 0.005 0.0172 0.032
Loa Loa (eye worm) hypothetical protein 0.005 0.0172 0.032
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0009 0.0015
Plasmodium falciparum acetyl-CoA synthetase, putative 0.002 0.0036 0.0147
Brugia malayi Cytochrome P450 family protein 0.0035 0.0104 0.0193
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0058 0.0206 0.0384
Echinococcus multilocularis axis inhibition protein axin 0.0037 0.0112 0.0112
Echinococcus granulosus dro:myosuppressin receptor 0.0025 0.0059 0.0059
Brugia malayi hypothetical protein 0.0025 0.0059 0.011
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0017 0.0023 0.0031
Loa Loa (eye worm) hypothetical protein 0.0112 0.0447 0.0832
Toxoplasma gondii thioredoxin reductase 0.038 0.1641 0.6773
Loa Loa (eye worm) oxidoreductase 0.002 0.0036 0.0066
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0215 0.0215
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0124 0.0665
Brugia malayi Kringle domain containing protein 0.0023 0.0049 0.0092
Trypanosoma brucei pyruvate kinase 1 0.0046 0.0152 0.0812
Echinococcus granulosus GPCR family 3 C terminal 0.0015 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0281 0.1198 0.1957
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0281 0.1198 0.6402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0129 0.0211
Schistosoma mansoni pyruvate kinase 0.0046 0.0152 0.0201
Echinococcus multilocularis X box binding protein 1 0.0191 0.0796 0.0796
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.008 0.0303 0.0494
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0035 0.0103 0.0189
Echinococcus granulosus tumor protein p63 0.0723 0.317 0.317
Echinococcus granulosus Regulator of G protein signaling 20 0.0037 0.0112 0.0112
Loa Loa (eye worm) DR-78 0.006 0.0215 0.0401
Brugia malayi PXA domain containing protein 0.0037 0.0112 0.0208
Schistosoma mansoni tyrosine kinase 0.0175 0.0729 0.0965
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.137 0.732
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0128 0.0516 0.0959
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Loa Loa (eye worm) steroid hormone receptor 0.0128 0.0516 0.0959
Trichomonas vaginalis DNA helicase recq, putative 0.0055 0.019 0.0311
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0037 0.0112 0.0182
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0026 0.0063 0.0063
Onchocerca volvulus 0.0042 0.0134 0.0219
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0124 0.1961
Brugia malayi hypothetical protein 0.0014 0.0009 0.0017
Schistosoma mansoni nuclear receptor 0.006 0.0215 0.0285
Mycobacterium ulcerans acyl-CoA synthetase 0.0068 0.0248 0.2071
Giardia lamblia Heat shock protein HSP 90-alpha 0.0142 0.0579 0.3092
Trypanosoma cruzi heat shock protein 90, putative 0.0074 0.0277 0.1481
Brugia malayi GnHR receptor homolog 0.0025 0.0059 0.011
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0059 0.0059
Toxoplasma gondii target of rapamycin (TOR), putative 0.0041 0.0129 0.0532
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0014 0.0008 0.0012
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0031 0.0084 0.0345
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Echinococcus granulosus histone lysine methyltransferase setb 0.0188 0.0784 0.0784
Brugia malayi neuropeptide F receptor 0.0025 0.0059 0.011
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0231
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0067 0.0247 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0104 0.0191
Giardia lamblia Replication factor C, subunit 1 0.0014 0.0008 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0032 0.0059
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0035 0.0103 0.055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Toxoplasma gondii Hsp90 domain-containing protein 0.0556 0.2423 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0209 0.0209
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0059 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0128 0.0516 0.0842
Trichomonas vaginalis heat shock protein, putative 0.0142 0.0579 0.0946
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Brugia malayi 6-phosphofructokinase 0.0281 0.1198 0.2229
Toxoplasma gondii microneme protein MIC2 0.0042 0.0134 0.0552
Onchocerca volvulus 0.0025 0.0059 0.0097
Echinococcus granulosus peptide allatostatin:somatostatin 0.0025 0.0059 0.0059
Giardia lamblia Ornithine decarboxylase 0.0061 0.0219 0.1166
Onchocerca volvulus 0.0025 0.0059 0.0097
Entamoeba histolytica heat shock transcription factor, putative 0.024 0.1016 0.5427
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0032 0.0059
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0026 0.0063 0.0117
Loa Loa (eye worm) TK/ALK protein kinase 0.0014 0.0012 0.0022
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0032 0.0032
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0029 0.0156
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0048 0.0199
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0035 0.0103 0.0192
Loa Loa (eye worm) RecQ helicase 0.0055 0.019 0.0354
Echinococcus multilocularis citrate lyase subunit beta protein 0.0037 0.0111 0.0111
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0035 0.0103 0.0225
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Brugia malayi Cytochrome P450 family protein 0.0117 0.0468 0.087
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0209 0.1118
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0096 0.0374 0.0697
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0026 0.0061 0.0326
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0136 0.0551 0.1026
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0068 0.0248 0.2071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0159 0.0847
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0104 0.0868
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0059 0.0078
Schistosoma mansoni neuropeptide receptor 0.0025 0.0059 0.0078
Brugia malayi cytoplasmic intermediate filament protein 0.0035 0.0103 0.0192
Schistosoma mansoni DNA helicase recq5 0.0031 0.0085 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0519 0.0687
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.008 0.0303 0.0563
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0029 0.0054
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0128 0.0516 0.0516
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0097 0.0378 0.0704
Chlamydia trachomatis DNA gyrase subunit B 0.0026 0.0061 0.1135
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0064 0.0231 0.0954
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0104 0.0556
Echinococcus multilocularis nibrin 0.0014 0.0008 0.0008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0025 0.0059 0.0059
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0132 0.0534 1
Schistosoma mansoni heat shock protein 0.0105 0.0416 0.0551
Brugia malayi Protein kinase domain containing protein 0.0105 0.0414 0.0771
Onchocerca volvulus Serine\/threonine kinase homolog 0.0432 0.1872 0.3057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0048
Plasmodium vivax DNA gyrase subunit B, putative 0.0026 0.0061 0.0252
Brugia malayi kinase, mitochondrial precursor 0.0026 0.0061 0.0114
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0022 0.0041
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0124 0.0231
Trypanosoma cruzi heat shock protein, putative 0.0105 0.0416 0.2224
Brugia malayi laminin-like protein K08C7.3 precursor 0.0052 0.018 0.0334
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0025 0.0059 0.011
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0026 0.0061 0.0114
Echinococcus multilocularis bloom syndrome protein 0.0055 0.019 0.019
Echinococcus multilocularis heat shock transcription factor 0.0015 0.0014 0.0014
Onchocerca volvulus 0.0025 0.0059 0.0097
Loa Loa (eye worm) hypothetical protein 0.0046 0.0152 0.0283
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1872 0.3057
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0025 0.0059 0.0078
Echinococcus multilocularis protein dispatched 1 0.0066 0.0243 0.0243
Brugia malayi Dopamine receptor 0.0025 0.0059 0.011
Leishmania major ATP-dependent phosphofructokinase 0.0281 0.1198 0.6402
Echinococcus multilocularis pyruvate kinase 0.0024 0.0052 0.0052
Entamoeba histolytica hypothetical protein 0.0144 0.0589 0.3148
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0104 0.0412 0.0412
Brugia malayi Pre-SET motif family protein 0.0176 0.073 0.1359
Schistosoma mansoni alpha-1 adrenergic receptor 0.0025 0.0059 0.0078
Treponema pallidum DNA ligase (lig) 0.0014 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0129 0.0523 0.0973
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0032 0.0089 0.0474
Schistosoma mansoni DNA polymerase eta 0.0073 0.0272 0.0361
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0067 0.0247 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0036 0.0297
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0059 0.0078
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0025 0.0059 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.008 0.0303 0.1618
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Schistosoma mansoni chromosome transmission fidelity factor 0.0014 0.0008 0.001
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0055 0.0192 0.1024
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0136 0.0551 0.2946
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.008 0.0303 0.0303
Schistosoma mansoni hypothetical protein 0.0025 0.0059 0.0078
Leishmania major pyruvate kinase 0.0046 0.0152 0.0812
Brugia malayi Doublecortin family protein 0.0013 0.0005 0.001
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0104 0.0868
Mycobacterium ulcerans heat shock protein 90 0.0154 0.0632 0.5278
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0124 0.0665
Loa Loa (eye worm) RGS-3 protein 0.0037 0.0112 0.0208
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0215 0.0215
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0009 0.0038
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Onchocerca volvulus 0.0106 0.0419 0.0684
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0128 0.0516 0.0959
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Brugia malayi hypothetical protein 0.1031 0.4543 0.8452
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0106 0.0173
Trichomonas vaginalis mismatch repair protein Mlh1B (mutL homolog) 0.0012 0 0.0001
Plasmodium falciparum flap endonuclease 1 0.0032 0.0089 0.0366
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0014 0.0009 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Schistosoma mansoni smad1 5 8 and 0.0017 0.0022 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0015
Schistosoma mansoni microtubule-associated protein tau 0.1706 0.7552 1
Echinococcus granulosus neuropeptide s receptor 0.0654 0.2863 0.2863
Toxoplasma gondii corepressor complex CRC230 0.0012 0 0.0002
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.014 0.0261
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Brugia malayi Cache domain containing protein 0.0454 0.1971 0.3668
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0035 0.0103 0.0103
Brugia malayi Latrophilin receptor protein 2 0.0073 0.0272 0.0507
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0128 0.0516 0.0516
Echinococcus multilocularis heat shock protein 90 0.0142 0.0579 0.0579
Trypanosoma brucei heat shock protein 84, putative 0.0105 0.0416 0.2224
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0104 0.0868
Loa Loa (eye worm) hypothetical protein 0.0083 0.0318 0.0593
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0128 0.0516 0.0959
Echinococcus multilocularis g-protein coupled receptor 0.0025 0.0059 0.0059
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0032 0.0032
Loa Loa (eye worm) programmed cell death 8 0.0035 0.0103 0.0192
Brugia malayi orphan nuclear receptor NR2E1 0.006 0.0215 0.0401
Echinococcus multilocularis regulator of G protein signaling 0.0037 0.0112 0.0112
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0035 0.0103 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0272 0.0507
Brugia malayi Probable DNA topoisomerase II 0.0026 0.0061 0.0114
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0029 0.0054
Plasmodium vivax thrombospondin-related anonymous protein 0.0042 0.0134 0.0552
Onchocerca volvulus Putative nachr subunit 0.0019 0.0032 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0104 0.0191
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0104 0.0868
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0059 0.0059
Brugia malayi hypothetical protein 0.0103 0.0404 0.0752
Loa Loa (eye worm) hypothetical protein 0.0012 0 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0146 0.0598 0.3197
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0052
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0132 0.0534 0.1211
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0048 0.0199
Trichomonas vaginalis diaminopimelate decarboxylase, putative 0.0061 0.0219 0.0357
Plasmodium vivax acetyl-CoA synthetase, putative 0.002 0.0036 0.0147
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Entamoeba histolytica acyl-CoA synthetase, putative 0.0068 0.0248 0.1326
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0032 0.0032
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0105 0.0416 0.2224
Schistosoma mansoni pyruvate kinase 0.0046 0.0152 0.0201
Trypanosoma cruzi target of rapamycin kinase 3 0.0044 0.0142 0.0757
Trypanosoma brucei heat shock protein 90, putative 0.0167 0.0693 0.3702
Brugia malayi AMP-binding enzyme family protein 0.002 0.0036 0.0066
Leishmania major mitochondrial DNA topoisomerase II 0.0026 0.0061 0.0326
Mycobacterium ulcerans hypothetical protein 0.0037 0.0111 0.0927
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0037 0.0111 0.0181
Schistosoma mansoni chromobox protein 0.0014 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0012 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0032 0.0059
Brugia malayi beta-NAC-like protein 0.0023 0.005 0.0093
Trichomonas vaginalis mismatch repair protein Mlh2 (mutL homolog) 0.0012 0 0.0001
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0104 0.0868
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0128 0.0516 0.0959
Schistosoma mansoni hypothetical protein 0.021 0.0885 0.1171
Schistosoma mansoni tar DNA-binding protein 0.017 0.0707 0.0936
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0132 0.0534 0.2854
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0059 0.0078
Echinococcus multilocularis Regulator of G protein signaling 20 0.0037 0.0112 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0209 0.0277
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0035 0.0103 0.055
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0026 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Onchocerca volvulus 0.0042 0.0134 0.0219
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0026 0.0061 0.009
Schistosoma mansoni transcription factor btf3 0.0023 0.005 0.0067
Echinococcus multilocularis voltage dependent calcium channel 0.0067 0.0247 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0048
Trichomonas vaginalis replication factor C large subunit, putative 0.0014 0.0008 0.0012
Trichomonas vaginalis flap endonuclease-1, putative 0.0032 0.0089 0.0145
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Plasmodium vivax pyruvate kinase 2, putative 0.0024 0.0052 0.0216
Entamoeba histolytica hypothetical protein 0.0064 0.0231 0.1235
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0098 0.0159
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0036 0.0029
Schistosoma mansoni loxhd1 0.0013 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0096 0.0374 0.0697
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0318 0.1314
Trypanosoma brucei unspecified product 0.0073 0.0272 0.1455
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.002 0.0036 0.0029
Schistosoma mansoni kinase 0.022 0.0926 0.1227
Echinococcus granulosus hypothetical protein 0.0025 0.0059 0.0059
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.005 0.0168 0.0695
Echinococcus granulosus orexin receptor type 2 0.0025 0.0059 0.0059
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0154 0.0632 0.3379
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0035 0.0103 0.055
Giardia lamblia DINP protein human, muc B family 0.0073 0.0272 0.1453
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0009 0.0012
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0318 0.07
Onchocerca volvulus 0.0025 0.0059 0.0097
Echinococcus multilocularis 0.01 0.0395 0.0395
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0029 0.0156
Loa Loa (eye worm) calcium channel 0.0067 0.0247 0.046
Entamoeba histolytica hypothetical protein 0.0037 0.0112 0.0597
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0013 0.0025
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0061 0.1135
Loa Loa (eye worm) CYP4Cod1 0.0065 0.0236 0.044
Loa Loa (eye worm) hypothetical protein 0.0029 0.0075 0.014
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0036 0.0058
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Brugia malayi 6-phosphofructokinase 0.0281 0.1198 0.2229
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0236 0.044
Trypanosoma cruzi trypanothione reductase, putative 0.038 0.1641 0.8768
Echinococcus granulosus transcription factor eb 0.019 0.0792 0.0792
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0114
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0067 0.0247 0.046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium ulcerans endonuclease IV 0.0083 0.0318 0.2658
Onchocerca volvulus 0.0015 0.0013 0.0022
Giardia lamblia Thioredoxin reductase 0.0035 0.0103 0.0548
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0029 0.0048
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0231
Onchocerca volvulus 0.0019 0.0032 0.0052
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0046 0.0152 0.0305
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0035 0.0065
Entamoeba histolytica hypothetical protein 0.0014 0.0009 0.0049
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0104 0.0556
Loa Loa (eye worm) hypothetical protein 0.0046 0.0153 0.0285
Trichomonas vaginalis ornithine decarboxylase, putative 0.0022 0.0044 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0763 0.101
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0032 0.0059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0128 0.0516 0.0516
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0104 0.0191
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0146 0.0598 0.0598
Plasmodium vivax heat shock protein 86, putative 0.0167 0.0693 0.286
Loa Loa (eye worm) 6-phosphofructokinase 0.0281 0.1198 0.2229
Schistosoma mansoni pyruvate kinase 0.0024 0.0052 0.0069
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0132 0.0534 0.4458
Brugia malayi RE15519p 0.0025 0.0059 0.011
Echinococcus granulosus smad 0.0017 0.0022 0.0022
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0134 0.0219
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0104 0.0868
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0048
Schistosoma mansoni neuropeptide receptor 0.0025 0.0059 0.0078
Echinococcus granulosus thioredoxin glutathione reductase 0.0381 0.1648 0.1648
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0035 0.0103 0.0189
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0026 0.0061 0.051
Echinococcus multilocularis thioredoxin glutathione reductase 0.0381 0.1648 0.1648
Brugia malayi ecdysone receptor 0.006 0.0215 0.0401
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0132 0.0534 0.2205
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.002 0.0036 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.019 0.0792 0.1474
Echinococcus granulosus chromobox protein 1 0.0085 0.0326 0.0326
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.002 0.0036 0.0297
Chlamydia trachomatis DNA ligase 0.0014 0.0008 0.0133
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0046 0.0153 0.0632
Brugia malayi Zona pellucida-like domain containing protein 0.0042 0.0134 0.0249
Brugia malayi von Willebrand factor type A domain containing protein 0.0042 0.0134 0.0249
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0128 0.0516 0.0842
Schistosoma mansoni flap endonuclease-1 0.0029 0.0075 0.01
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0012
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0227 0.0957 0.1267
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0025 0.0059 0.0059
Echinococcus multilocularis muscleblind protein 1 0.0096 0.0374 0.0374
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0085 0.0085
Echinococcus multilocularis slit 2 protein 0.0052 0.018 0.018
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0035 0.0103 0.0425
Echinococcus multilocularis expressed protein 0.0031 0.0084 0.0084
Echinococcus multilocularis chromobox protein 1 0.0085 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Schistosoma mansoni regulator of G protein signaling 0.0039 0.012 0.0159
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0032 0.0042
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0104 0.0868
Treponema pallidum ATP-dependent DNA helicase 0.0016 0.0017 0.0036
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0326 0.0532
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0036 0.0029
Trichomonas vaginalis DNA helicase recq1, putative 0.0055 0.019 0.0311
Trypanosoma brucei heat shock protein, putative 0.0167 0.0693 0.3702
Echinococcus multilocularis microtubule associated protein 2 0.1706 0.7552 0.7552
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0128 0.0519 0.0519
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0009 0.0038
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0032 0.0089 0.0474
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0026 0.0061 0.009
Echinococcus granulosus heat shock protein 90 0.0142 0.0579 0.0579
Echinococcus multilocularis dna polymerase kappa 0.0073 0.0272 0.0272
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0035 0.0103 0.0425
Brugia malayi Pre-SET motif family protein 0.1218 0.5375 1
Trichomonas vaginalis mismatch repair protein Pms1 (mutL homolog) 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.001
Loa Loa (eye worm) intermediate filament protein 0.0065 0.0238 0.0444
Brugia malayi von Willebrand Factor 0.0042 0.0134 0.0249
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0035 0.0103 0.055
Trypanosoma brucei unspecified product 0.005 0.0171 0.0916
Schistosoma mansoni rab6-interacting 0.0013 0.0005 0.0007
Echinococcus granulosus bloom syndrome protein 0.0055 0.019 0.019
Echinococcus multilocularis replication factor c subunit 1 0.0014 0.0008 0.0008
Onchocerca volvulus 0.006 0.0215 0.0352
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0048 0.0257
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0048 0.0257
Brugia malayi nuclear hormone receptor 0.0128 0.0516 0.0959
Entamoeba histolytica disulphide oxidoreductase, putative 0.0035 0.0103 0.055
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0223 0.0942 0.1247
Loa Loa (eye worm) pyruvate kinase 0.0046 0.0152 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0128 0.0516 0.0959
Entamoeba histolytica heat shock transcription factor, putative 0.0015 0.0014 0.0076
Plasmodium vivax endoplasmin, putative 0.0167 0.0693 0.286
Leishmania major hypothetical protein, conserved 0.0035 0.0103 0.055
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0037 0.0112 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0156 0.0254
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Brugia malayi Bromodomain containing protein 0.0054 0.0188 0.035
Toxoplasma gondii subtilisin SUB12 0.0015 0.0013 0.0055
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0867 0.3811 0.8978
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0045 0.0088
Echinococcus granulosus Protein patched homolog 1 0.0058 0.0206 0.0206
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0168 0.0694
Brugia malayi DNA mismatch repair protein MutL containing protein 0.0012 0 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0511 0.2227 0.4143
Loa Loa (eye worm) hypothetical protein 0.008 0.0303 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0029 0.0048
Brugia malayi hypothetical protein 0.0013 0.0005 0.001
Schistosoma mansoni metabotropic glutamate receptor 0.0077 0.0292 0.0386
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0048 0.0257
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.0763 0.0763
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0128 0.0516 0.0959
Schistosoma mansoni hypothetical protein 0.0651 0.2847 0.377
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0067 0.0247 0.0327
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0014 0.0009 0.0038
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0048 0.0199
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0009 0.0049
Echinococcus multilocularis transcription factor btf3 0.0023 0.005 0.005
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0042 0.0134 0.0249
Trichomonas vaginalis heat shock protein, putative 0.0154 0.0632 0.1033
Onchocerca volvulus 0.0013 0.0005 0.0009
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0146 0.0598 0.3197
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0126 0.0508 0.0508
Brugia malayi Protein kinase domain containing protein 0.0014 0.0012 0.0022
Plasmodium vivax thioredoxin reductase, putative 0.038 0.1641 0.6773
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0059 0.0059
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0057 0.0202 0.1078
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0042 0.0134 0.0552
Loa Loa (eye worm) TK/EGFR protein kinase 0.0326 0.1398 0.2601
Schistosoma mansoni glutaminase 0.0215 0.0904 0.1196
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0025 0.0059 0.011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0066
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0067 0.0247 0.0247
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0025 0.0059 0.011
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0035 0.0103 0.0189
Echinococcus granulosus regulator of G protein signaling 3 0.0037 0.0112 0.0112
Loa Loa (eye worm) nuclear receptor NHR-67 0.006 0.0215 0.0401
Leishmania major cytochrome p450-like protein 0.0035 0.0104 0.0556
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0037 0.0111 0.0593
Onchocerca volvulus 0.0019 0.0032 0.0052
Brugia malayi hypothetical protein 0.0084 0.0321 0.0598
Onchocerca volvulus 0.0013 0.0005 0.0009
Entamoeba histolytica recQ family DNA helicase 0.0016 0.0017 0.0092
Schistosoma mansoni heat shock transcription factor 0.0015 0.0014 0.0019
Schistosoma mansoni hypothetical protein 0.0191 0.0796 0.1055
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.0419 0.0555
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0132 0.0534 0.4458
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0035 0.0103 0.0103
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0048 0.0257
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0124 0.0665
Mycobacterium ulcerans two component sensor kinase MprB 0.0026 0.0061 0.051
Brugia malayi follicle stimulating hormone receptor 0.0511 0.2227 0.4143
Schistosoma mansoni topbp1 0.0014 0.0008 0.001
Echinococcus granulosus intermediate filament protein 0.0065 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Echinococcus granulosus voltage dependent calcium channel subunit 0.1026 0.4519 0.4519
Mycobacterium tuberculosis Probable oxidoreductase 0.0964 0.4243 1
Echinococcus granulosus neuropeptide receptor 0.0025 0.0059 0.0059
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0045 0.0083
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0037 0.0111 0.0593
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0085 0.0158
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0188 0.0784 0.0784
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Loa Loa (eye worm) hypothetical protein 0.0128 0.0516 0.0959
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0026 0.0061 0.0958
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0068 0.0248 0.0568
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0035 0.0103 0.086
Schistosoma mansoni hypothetical protein 0.0025 0.0059 0.0078
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.0454 0.1971 0.3668
Brugia malayi MH2 domain containing protein 0.0017 0.0022 0.0041
Echinococcus granulosus nAChR subunit 0.0019 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0026
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0168 0.0344
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0059 0.0059
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.002 0.0036 0.0066
Plasmodium falciparum DNA gyrase subunit B 0.0026 0.0061 0.0252
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0014 0.001 0.0052
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Brugia malayi steroid hormone receptor 0.0128 0.0516 0.0959
Leishmania major hypothetical protein, conserved 0.0047 0.0159 0.0847
Schistosoma mansoni serine-rich repeat protein 0.053 0.2309 0.3057
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0132 0.0534 0.2205
Echinococcus multilocularis expressed protein 0.0719 0.3152 0.3152
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.002 0.0036 0.0297
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0026 0.0063 0.0117
Brugia malayi CXXC zinc finger family protein 0.002 0.0035 0.0065
Brugia malayi Zona pellucida-like domain containing protein 0.0042 0.0134 0.0249
Schistosoma mansoni thyroid hormone receptor 0.0253 0.1076 0.1425
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0045 0.0051
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0281 0.1198 0.2539
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0026 0.0061 0.051
Brugia malayi hypothetical protein 0.006 0.0215 0.0401
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Brugia malayi hypothetical protein 0.0023 0.0052 0.0096
Trypanosoma cruzi transcription factor btf3, putative 0.0023 0.005 0.0268
Brugia malayi PXA domain containing protein 0.0037 0.0112 0.0208
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0132 0.0534 0.2854
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0114
Echinococcus granulosus serotonin receptor 0.0025 0.0059 0.0059
Brugia malayi nuclear receptor NHR-88 0.0128 0.0516 0.0959
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0104 0.0868
Plasmodium falciparum heat shock protein 90 0.0167 0.0693 0.286
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.008 0.0303 0.0494
Echinococcus granulosus chromobox protein 1 0.0085 0.0326 0.0326
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0059 0.011
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.008 0.0303 0.1615
Entamoeba histolytica hypothetical protein 0.0144 0.0589 0.3148
Brugia malayi Cation transporter family protein 0.0019 0.0032 0.0059
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0134 0.0715
Mycobacterium leprae Probable two-component sensor kinase 0.0026 0.0061 0.0126
Schistosoma mansoni 6-phosphofructokinase 0.0281 0.1198 0.1587
Echinococcus multilocularis glutamate synthase 0.0035 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0206 0.0337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Entamoeba histolytica hypothetical protein 0.0037 0.0112 0.0597
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0035 0.0103 0.1622
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0043 0.0139 0.0259
Schistosoma mansoni blooms syndrome DNA helicase 0.0039 0.012 0.0159
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0025 0.0059 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0159 0.0654
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0272 0.1455
Brugia malayi G protein-coupled receptor F59B2.13 0.0025 0.0059 0.011
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0107 0.0569
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0013 0.0055
Schistosoma mansoni hypothetical protein 0.0126 0.0508 0.0673
Giardia lamblia GTOR 0.0055 0.0192 0.1021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0168 0.0223
Echinococcus granulosus nuclear receptor nhr 48 0.006 0.0215 0.0215
Trichomonas vaginalis sensor histidine kinase, putative 0.0026 0.0061 0.01
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0036 0.019
Mycobacterium ulcerans hypothetical protein 0.0037 0.0111 0.0927
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Brugia malayi MH1 domain containing protein 0.0017 0.0022 0.0041
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Brugia malayi Flap endonuclease-1 0.0032 0.0089 0.0165
Echinococcus granulosus collagen alpha 1VII chain 0.0042 0.0134 0.0134
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0036 0.0066
Trypanosoma brucei developmentally regulated phosphoprotein 0.0026 0.0061 0.0326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0128 0.0516 0.0959
Loa Loa (eye worm) hypothetical protein 0.0037 0.0114 0.0212
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0114
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0128 0.0516 0.0516
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.002 0.0038
Mycobacterium leprae PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE) 0.0024 0.0052 0.0105
Schistosoma mansoni chromobox protein 0.0014 0.0009 0.0012
Entamoeba histolytica heat shock protein 90, putative 0.0167 0.0693 0.3702
Schistosoma mansoni polycystin 1-related 0.0013 0.0005 0.0007
Schistosoma mansoni tar DNA-binding protein 0.017 0.0707 0.0936
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0032 0.0059
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0037 0.0111 0.0208
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0168 0.0168
Onchocerca volvulus 0.0025 0.0059 0.0097
Brugia malayi hypothetical protein 0.0023 0.0052 0.0096
Onchocerca volvulus 0.0025 0.0059 0.0097
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0035 0.0103 0.086
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0035 0.0103 0.055
Schistosoma mansoni hypothetical protein 0.053 0.2309 0.3057
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0297
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0085 0.0085
Brugia malayi glutaminase DH11.1 0.0215 0.0904 0.1681
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Schistosoma mansoni hypothetical protein 0.0025 0.0059 0.0078
Schistosoma mansoni hypothetical protein 0.0056 0.0197 0.0261
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0032 0.0059
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0036 0.0066
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0098 0.0159
Trichomonas vaginalis heat shock protein, putative 0.0167 0.0693 0.1132
Trypanosoma brucei mismatch repair protein MLH1 0.0012 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.014 0.0261
Onchocerca volvulus 0.0025 0.0059 0.0097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0073 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0023 0.0049 0.0092
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0104 0.0868
Echinococcus granulosus somatostatin receptor 0.0025 0.0059 0.0059
Echinococcus granulosus metabotropic glutamate receptor 5 0.0114 0.0454 0.0454
Schistosoma mansoni glutamate synthase 0.0035 0.0103 0.0136
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0763 0.6367
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0168 0.0694
Schistosoma mansoni survival motor neuron protein 0.021 0.0885 0.1171
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0132 0.0534 0.2854
Brugia malayi Endoplasmin precursor 0.0167 0.0693 0.1289
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.016 0.0261
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0009 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0285 0.0466
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0146 0.0598 0.1113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0035 0.0103 0.0168
Onchocerca volvulus 0.0014 0.0009 0.0015
Brugia malayi neuropeptide F receptor 0.0025 0.0059 0.011
Echinococcus multilocularis muscleblind protein 0.0096 0.0374 0.0374
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0009 0.0049
Echinococcus granulosus metabotropic glutamate receptor 2 0.0077 0.0292 0.0292
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0017 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0432 0.1872 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0025
Schistosoma mansoni retinoic acid receptor RXR 0.0128 0.0516 0.0683
Schistosoma mansoni zinc finger protein 0.0015 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Trypanosoma cruzi cytochrome P450, putative 0.0065 0.0236 0.1262
Brugia malayi G-protein coupled receptor 0.0025 0.0059 0.011
Leishmania major heat shock protein 83-1 0.0167 0.0693 0.3702
Brugia malayi hypothetical protein 0.0149 0.0609 0.1133
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0209 0.1118
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0035 0.0103 0.0425
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0105 0.0416 0.0416
Schistosoma mansoni hypothetical protein 0.0651 0.2847 0.377
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0067 0.0247 0.0247
Mycobacterium tuberculosis Probable two component sensor kinase 0.0026 0.0061 0.009
Echinococcus multilocularis cpg binding protein 0.0022 0.0046 0.0046
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0026 0.0061 0.01
Echinococcus multilocularis GPCR, family 2 0.0073 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) glutaminase 2 0.0215 0.0904 0.1681
Schistosoma mansoni hypothetical protein 0.0073 0.0272 0.0361
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Schistosoma mansoni patched 1 0.0058 0.0206 0.0273
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0032 0.0059
Schistosoma mansoni laminin gamma-3 chain 0.0052 0.018 0.0238
Echinococcus multilocularis thyroid hormone receptor alpha 0.0253 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0052 0.018 0.0334
Brugia malayi intermediate filament protein 0.0065 0.0238 0.0444
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0032 0.0059
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0027 0.0067 0.0357
Trichomonas vaginalis receptor histidine kinase, putative 0.0026 0.0061 0.01
Trypanosoma brucei mismatch repair protein PMS1, putative 0.0012 0 0.0003
Echinococcus granulosus chromobox protein 2 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0032 0.0042
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0128 0.0516 0.0959
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0059 0.0078
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0168 0.0313
Leishmania major developmentally regulated phosphoprotein-like protein 0.0026 0.0061 0.0326
Loa Loa (eye worm) hypothetical protein 0.005 0.0172 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Loa Loa (eye worm) hypothetical protein 0.005 0.0172 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0032 0.0032
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0059 0.0059
Mycobacterium ulcerans hypothetical protein 0.0023 0.0048 0.0402
Entamoeba histolytica hypothetical protein 0.0037 0.0112 0.0597
Plasmodium vivax SET domain protein, putative 0.0176 0.073 0.3014
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.002 0.0036 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0281 0.1198 0.1957
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0128 0.0516 0.0683
Schistosoma mansoni heat shock transcription factor 0.0015 0.0014 0.0019
Schistosoma mansoni amine GPCR 0.0025 0.0059 0.0078
Echinococcus multilocularis neurogenic locus notch protein 0.0052 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0233 0.0434
Schistosoma mansoni cpg binding protein 0.0022 0.0046 0.0061
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0032 0.0032
Mycobacterium leprae putative cytochrome p450 0.0035 0.0104 0.0228
Plasmodium vivax heat shock protein 90, putative 0.0105 0.0416 0.1718
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0036 0.019
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0146 0.0598 0.0792
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.014 0.0186
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0168 0.0168
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0012 0.0001 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.0303 0.1618
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0248 0.0533
Echinococcus granulosus heat shock protein 0.0167 0.0693 0.0693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0192 0.0313
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0154 0.0632 0.1475
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0025 0.0059 0.0059
Schistosoma mansoni zinc finger protein 0.006 0.0215 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0059
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0048 0.0257
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0132 0.0534 0.8446
Brugia malayi PAN domain containing protein 0.0015 0.0013 0.0025
Schistosoma mansoni lamin 0.0065 0.0238 0.0316
Brugia malayi putative neuropeptide receptor 0.0025 0.0059 0.011
Echinococcus granulosus tyrosine protein kinase shark 0.0174 0.0723 0.0723
Brugia malayi phosphofructokinase 0.0281 0.1198 0.2229
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0272 0.1455
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0079 0.0299 0.0556
Trypanosoma brucei DNA polymerase eta, putative 0.0073 0.0272 0.1455
Onchocerca volvulus Poor gastrulation protein homolog 0.0015 0.0014 0.0023
Schistosoma mansoni tyrosine kinase 0.017 0.0706 0.0934
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0009 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0059 0.0059
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0168 0.0899
Entamoeba histolytica heat shock transcription factor, putative 0.024 0.1016 0.5427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0059 0.0059
Brugia malayi ecdysteroid receptor 0.0128 0.0516 0.0959
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0026 0.0061 0.01
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0032 0.0042
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0026 0.0061 0.01
Leishmania major hypothetical protein, conserved 0.0035 0.0103 0.055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0763 0.6367
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0104 0.0868
Brugia malayi hypothetical protein 0.0014 0.0008 0.0014
Schistosoma mansoni hypothetical protein 0.0056 0.0197 0.0261
Loa Loa (eye worm) hypothetical protein 0.0047 0.0159 0.0295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.011
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0128 0.0516 0.0959
Loa Loa (eye worm) CUTiclin-Like family member 0.0042 0.0134 0.0249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0059 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0068 0.0248 0.0462
Echinococcus multilocularis Chromo domain 0.0014 0.0009 0.0009
Brugia malayi nuclear hormone receptor family member nhr-6 0.006 0.0215 0.0401
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0042 0.0134 0.0552
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0124 0.0513
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.002 0.0032
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0073 0.0272 0.0507
Brugia malayi nuclear receptor RXR 0.0067 0.0247 0.046
Onchocerca volvulus 0.0019 0.0032 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0128 0.0516 0.0516
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0964 0.4243 1
Trypanosoma brucei DNA topoisomerase ii 0.0026 0.0061 0.0326
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0042 0.0134 0.0552
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0129
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.005 0.0172 0.3215
Echinococcus multilocularis insulin receptor 0.0105 0.0414 0.0414
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0032 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.008 0.0303 0.0401
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0247 0.0328
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0084 0.0321 0.0321
Giardia lamblia Pyruvate kinase 0.0024 0.0052 0.0277
Onchocerca volvulus 0.0025 0.0059 0.0097
Loa Loa (eye worm) hypothetical protein 0.0067 0.0247 0.046
Entamoeba histolytica heat shock transcription factor, putative 0.024 0.1016 0.5427
Schistosoma mansoni lamin 0.0065 0.0238 0.0316
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0026 0.0063 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0142 0.0231
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0104 0.0556
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0104 0.0228
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0104 0.0191
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0055 0.0192 0.1024
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0432 0.1872 0.1872
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus granulosus zinc finger protein 0.0015 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0281 0.1198 0.1957
Schistosoma mansoni hypothetical protein 0.0073 0.0272 0.0361
Onchocerca volvulus 0.019 0.0792 0.1294
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0032 0.0059
Chlamydia trachomatis endonuclease IV 0.0083 0.0318 0.5958
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0128 0.0519 0.0519
Entamoeba histolytica hypothetical protein 0.0014 0.001 0.0052
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0014 0.0008 0.0031
Onchocerca volvulus 0.0015 0.0013 0.0022
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0068 0.0248 0.2071
Brugia malayi hypothetical protein 0.0067 0.0247 0.046
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0067 0.0247 0.0327
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0055 0.0192 0.1024
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0035 0.0103 0.0425
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0029 0.0156
Schistosoma mansoni hypothetical protein 0.0073 0.0272 0.0361
Schistosoma mansoni tyrosine kinase 0.0174 0.0723 0.0958
Schistosoma mansoni nAChR subunit 0.0019 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0387 0.1673 0.3112
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0082
Trypanosoma brucei acetyl-CoA synthetase, putative 0.002 0.0036 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0012
Leishmania major hypothetical protein, conserved 0.0319 0.137 0.732
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0053 0.0098
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0132 0.0534 0.2854
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0401
Schistosoma mansoni acetyl-CoA synthetase 0.002 0.0036 0.0047
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0061 0.0219 0.0903
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0249
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0032 0.0032
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0035 0.0103 0.0192
Plasmodium falciparum heat shock protein 90, putative 0.0093 0.0363 0.1498
Echinococcus multilocularis alkaline phosphatase 0.0104 0.0412 0.0412
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0026 0.0061 0.0326
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0031 0.0084 0.0345
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0032 0.0032
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0014 0.0012 0.0012
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0035 0.0103 0.055
Leishmania major basic transcription factor 3a, putative 0.0023 0.005 0.0268
Echinococcus multilocularis neuropeptide receptor A26 0.0654 0.2863 0.2863
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0013 0.0025
Entamoeba histolytica heat shock protein 90, putative 0.0167 0.0693 0.3702
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0055 0.0192 0.0254
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0032 0.0088 0.0088
Onchocerca volvulus 0.0035 0.0103 0.0168
Schistosoma mansoni lipoxygenase 0.0078 0.0295 0.039
Chlamydia trachomatis pyruvate kinase 0.0046 0.0152 0.2837
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0105 0.0415 0.0549
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0015 0.0014 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0319 0.137 0.732

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 16 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557
IC50 (binding) = 16 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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